CuGenDBv2

Gene ID	CSPI03G29600
Organism	Cucumis sativus L. var. sativus cv. PI 183967 (Cucumber (PI 183967) v1)
Description	DNA topoisomerase 2
Genome location	Chr3:27144208..27151229
RNA-Seq Expression	CSPI03G29600
Synteny	CSPI03G29600
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0043231 - intracellular membrane-bounded organelle (cellular component) GO:0003677 - DNA binding (molecular function) GO:0046872 - metal ion binding (molecular function) GO:0005524 - ATP binding (molecular function) GO:0003918 - DNA topoisomerase type II (ATP-hydrolyzing) activity (molecular function)
InterPro domains	IPR013506 - DNA topoisomerase, type IIA, subunit B, domain 2 IPR036890 - Histidine kinase/HSP90-like ATPase superfamily IPR034157 - DNA topoisomerase 2, TOPRIM domain IPR031660 - C-terminal associated domain of TOPRIM IPR020568 - Ribosomal protein S5 domain 2-type fold IPR018522 - DNA topoisomerase, type IIA, conserved site IPR014721 - Ribosomal protein S5 domain 2-type fold, subgroup IPR013760 - DNA topoisomerase, type IIA-like domain superfamily IPR013759 - DNA topoisomerase, type IIA, subunit B, C-terminal IPR013758 - DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta IPR013757 - Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily IPR006171 - TOPRIM domain IPR003594 - Histidine kinase/HSP90-like ATPase IPR002205 - DNA topoisomerase, type IIA, subunit A/C-terminal IPR001241 - DNA topoisomerase, type IIA IPR001154 - DNA topoisomerase II, eukaryotic-type

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0048368.1 DNA topoisomerase 2 [Cucumis melo var. makuwa]

0.0e+00

96.2

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Query:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MVVEKKRPLQNSN ANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEN+KMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFS+EFVIETADGRRLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVV
        PIITKCK+GDNWTRVTFKPDL KFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPV+SFQDYVDLYLKSASS QAEPPKRYHI+PNERWEIVV
Subjt:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIAN+VMTAVNKKNKNANVKAHNVK+YLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLR
        ENKEIQYIKQILGLQQGKEYNNA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYE+WKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
        RFLFP+DDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRML+GETMLPMDPWYRGFSGTIEKTATKEGGTTYT+S
Subjt:  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKH  DKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPK
        TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELC+DRDKLKGEVDDLRKATPKSLWLNDLD LEKELDE+DRNDAQTMELRKQQR+KAN DLKPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPK

Query:  VSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETEV
        +SRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAV D+D+DDEVLELKDRLAAYKIESSPEPSEVSAMETEV
Subjt:  VSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETEV

Query:  QEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSGI
        QEV  QAAKKKEPSKRAPAKKKTTAKSAQISISDD++D DFEIKEVDP AAKKGGGR   GGRKAAA N KTTK PAAG KLGQKLITQMLEP AENSGI
Subjt:  QEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSGI

Query:  SPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEV---QLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASLDED
        SPEKKVRKIRASPFNKKSGSLLGR I EEEED  +DEGK+MGSAS ETSEEV   Q A GRSRRANR TQVRYVLSDSD E  SQDSDFDEDEASLDED
Subjt:  SPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEV---QLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASLDED

KAG7018075.1 DNA topoisomerase 2 [Cucurbita argyrosperma subsp. argyrosperma]

0.0e+00

90.22

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Query:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSNAANVDS+PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYEN+KMVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFS+EFVIETADGRRLKKYKQVF+DNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVV
        PIITKCK+GDNWT+VTFKPDL KFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPV+SFQDYVD YLKSA++ Q EPPKRYHIRPNERWEIVV
Subjt:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHV+YITNQIAN+VMT VNKKNKNANVKAHNVKSYLWVFINALIDNP+FDSQTKETLT R +SFGSACELTPDFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLR
        ENKEIQYIKQILGLQQGKEYNNA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYEAWK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD++DGEAIELAFSKKKIE+RKNWLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
        RFLFP+DDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRNVRRML GE MLPMDPWYRGFSGTIEKTATKEGGT+YTVS
Subjt:  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRI ELPVRRWT+DYKDFLDSVTRV++K+DKDKEKAAKDPFIEQADHHSDDK VSIDVHLTEENM+LA+QEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEF+EKRKR LL+NLE ELLKLENKVRFILAVVN EI VSNR++VDLFHELQ KGFTPFPKKTKSVEPE+AGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPK
        TDEAEESPEVVKGER+SDYEYLLAL IGTLTIEKVQELC++RDK KGEV++LRKATPKSLWL DLDYLEKELDEMDRNDAQ  E+RKQQR K N D+KPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPK

Query:  VSRNAPKAPRNSKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETE
        +SRNAPKAPRNSKKTSN ET+TESMD TT SSTTTEVANNPVVKPKGKAAPRKAPAKK+GKAAVLDDD+DDEVLELKDRLAAYK+ESSPEPSEVSAMETE
Subjt:  VSRNAPKAPRNSKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETE

Query:  VQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSG
        V +V Q AAKKKEPSKRA AKKKTTAKSAQ  ISDD +DGDFEIKE+ PPAAKKGGGR      K     +KTTK     A+LGQKLITQMLEP  ENSG
Subjt:  VQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSG

Query:  ISPEKKVRKIRASPFNKKSGSLLGRTIGEEEE--DENDDEGKLMGSASFETSEE----VQLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASL
        ISPEKKVRKIR SPFNKKSGS+LGR IGEEEE  +E  +EGK+MGSAS ET++E    V LARGRS+R NR TQVRYV+SDSD E   +DSDFDE EA+L
Subjt:  ISPEKKVRKIRASPFNKKSGSLLGRTIGEEEE--DENDDEGKLMGSASFETSEE----VQLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASL

Query:  DED
        DED
Subjt:  DED

XP_008461811.1 PREDICTED: DNA topoisomerase 2 [Cucumis melo]

0.0e+00

96.2

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Query:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MVVEKKRPLQNSN ANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEN+KMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFS+EFVIETADGRRLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVV
        PIITKCK+GDNWTRVTFKPDL KFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPV+SFQDYVDLYLKSASS QAEPPKRYHI+PNERWEIVV
Subjt:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIAN+VMTAVNKKNKNANVKAHNVK+YLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLR
        ENKEIQYIKQILGLQQGKEYNNA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYE+WKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
        RFLFP+DDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRML+GETMLPMDPWYRGFSGTIEKTATKEGGTTYT+S
Subjt:  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKH  DKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPK
        TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELC+DRDKLKGEVDDLRKATPKSLWLNDLD LEKELDE+DRNDAQTMELRKQQR+KAN DLKPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPK

Query:  VSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETEV
        +SRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAV D+D+DDEVLELKDRLAAYKIESSPEPSEVSAMETEV
Subjt:  VSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETEV

Query:  QEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSGI
        QEV  QAAKKKEPSKRAPAKKKTTAKSAQISISDD++D DFEIKEVDP AAKKGGGR   GGRKAAA N KTTK PAAG KLGQKLITQMLEP AENSGI
Subjt:  QEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSGI

Query:  SPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEV---QLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASLDED
        SPEKKVRKIRASPFNKKSGSLLGR I EEEED  +DEGK+MGSAS ETSEEV   Q A GRSRRANR TQVRYVLSDSD E  SQDSDFDEDEASLDED
Subjt:  SPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEV---QLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASLDED

XP_011651769.2 DNA topoisomerase 2 [Cucumis sativus]

0.0e+00

99.67

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Query:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVV
        PIITKCK GDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVV
Subjt:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLR
        ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
        RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
Subjt:  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPK
        TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPK

Query:  VSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLD---DDEDDEVLELKDRLAAYKIESSPEPSEVSAME
        VSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLD   DDEDDEVLELKDRLAAYKIESSPEPSEVSAME
Subjt:  VSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLD---DDEDDEVLELKDRLAAYKIESSPEPSEVSAME

Query:  TEVQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAEN
        TEVQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGR GGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAEN
Subjt:  TEVQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAEN

Query:  SGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEVQLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASLDED
        SGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEVQLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASLDED
Subjt:  SGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEVQLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASLDED

XP_038905935.1 DNA topoisomerase 2 [Benincasa hispida]

0.0e+00

91.21

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Query:  MVVEKKRPLQNSNAANVDSNP-AGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSM
        M VEKKRPLQNSNAANVDS+P AGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEN+KMVHRS+SYVPGLYKIFDEILVNAADNKQRDPSM
Subjt:  MVVEKKRPLQNSNAANVDSNP-AGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSM

Query:  DSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKS
        DSVKV+IDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFS+EFVIETADG+R+KKYKQVFNDNMGKKS
Subjt:  DSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKS

Query:  EPIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIV
        EPIITKCK GDNWT+VTFKPDL KFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVP++SFQDYVDLYLKSAS+ Q EPPKRYHI+PN+RWEIV
Subjt:  EPIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKN
        VTLSEGQFQQVSFVNGI+TIKGGTHV+YITNQI+N+VMTAVNKKNKNANVKAHNVK+YLWVFINALIDNPSFDSQTKETLTKR+NSFGS CELTP+FLKN
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKN

Query:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA+SKQI
Subjt:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESL
        TENKEIQYIKQILGLQQGKEYNNA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYE+WKESL
Subjt:  TENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESL

Query:  RGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQR
        RGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQT KLIKYSDFVNKELILFSMADLQR
Subjt:  RGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQR

Query:  SIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNV
        SIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRN GGKDHASSRYIYTKLSNV
Subjt:  SIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNV

Query:  TRFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTV
        TRFLFP+DDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDII+NVRRML+G TMLPMDPWYRGFSGTIEKTATKEGGT+YTV
Subjt:  TRFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTV

Query:  SGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMH
        SGIIEEVSDT LRIVELPVRRWT+DYKDFLDSVT+VA+KHDKDKEKAAK+PFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMH
Subjt:  SGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMH

Query:  LFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASN
        LFDANGVIKKYDTPEQILEEFFPLRL+FYEKRKR LL+NLEMELLKLENKVRFIL VVNEEI V NR+KVDLFHELQAKGFTPFPKK KSVEPE+AGAS+
Subjt:  LFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASN

Query:  ETDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKP
        E DEAEESPEVVK  R+SDYEYLL+L IGTLTIEKVQELC++RDKLKGEVDDLRKATPK+LWLNDLD LEKELDEMD NDAQ ME RK+QR+K N DLKP
Subjt:  ETDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKP

Query:  KVSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETE
        K+SRNAPKAPRN KKTSN E VTESMDTT+SSTT EVANNPVVKPKGKAAPRKAPA KKGKAAVLDDD DDEVLELKDRLAAYKIESSPEPSEVS METE
Subjt:  KVSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETE

Query:  VQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISIS---DDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAE
        V +V  QAAKKKEP+KRA AKKKTTAKSAQ+S+S   DDD+D DFE+KEV PPA KKGGGR  GGGRKAAA N+KTTKPPAA AKLGQKLIT+MLEP AE
Subjt:  VQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISIS---DDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAE

Query:  NSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDD-----EGKLMGSASFETSEE----VQLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFD
        NSGISPEKKVRKIRASPFNKKSGS+LGRTIGEE+E+E ++     E K+MGSAS ET++E    V  ARGRS RANR TQVRYV+SD D E  S+DSD D
Subjt:  NSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDD-----EGKLMGSASFETSEE----VQLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFD

Query:  ED
        ED
Subjt:  ED

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LEU2 DNA topoisomerase 2

0.0e+00

98.5

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Query:  MYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQNCISVFNNGDGVPVEIHQEE
        MYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQNCISVFNNGDGVPVEIHQEE
Subjt:  MYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQNCISVFNNGDGVPVEIHQEE

Query:  KVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSEPIITKCKDGDNWTRVTFKPDLEKFNMTHLE
        KVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSEPIITKCK GDNWTRVTFKPDLEKFNMTHLE
Subjt:  KVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSEPIITKCKDGDNWTRVTFKPDLEKFNMTHLE

Query:  DDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVEYITN
        DDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVEYITN
Subjt:  DDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVEYITN

Query:  QIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKT
        QIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKT
Subjt:  QIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKT

Query:  EKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNARALRYGH
        EKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNARALRYGH
Subjt:  EKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNARALRYGH

Query:  LMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLT
        LMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLT
Subjt:  LMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLT

Query:  KHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKV
        KHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFE         KL    + +  ELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKV
Subjt:  KHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKV

Query:  SQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPRDDDKLLNYLNEDGQSIEPTWYMPI
        SQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPRDDDKLLNYLNEDGQSIEPTWYMPI
Subjt:  SQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPRDDDKLLNYLNEDGQSIEPTWYMPI

Query:  IPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLD
        IPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLD
Subjt:  IPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLD

Query:  SVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEK
        SVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEK
Subjt:  SVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEK

Query:  RKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETDEAEESPEVVKGERISDYEYLLALPIGTL
        RKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETDEAEESPEVVKGERISDYEYLLALPIGTL
Subjt:  RKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETDEAEESPEVVKGERISDYEYLLALPIGTL

Query:  TIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPKVSRNAPKAPRNSKKTSNVETVTESMDTTYS
        TIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPKVSRNAPKAPRNSKKTSNVETVTESMDTTYS
Subjt:  TIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPKVSRNAPKAPRNSKKTSNVETVTESMDTTYS

Query:  STTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLD---DDEDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQEVQQQAAKKKEPSKRAPAKKKTTAKS
        STTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLD   DDEDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQEVQQQAAKKKEPSKRAPAKKKTTAKS
Subjt:  STTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLD---DDEDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQEVQQQAAKKKEPSKRAPAKKKTTAKS

Query:  AQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSGISPEKKVRKIRASPFNKKSGSLLGRTIG
        AQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSGISPEKKVRKIRASPFNKKSGSLLGRTIG
Subjt:  AQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSGISPEKKVRKIRASPFNKKSGSLLGRTIG

Query:  EEEEDENDDEGKLMGSASFETSEEVQLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASLDED
        EEEEDENDDEGKLMGSASFETSEEVQLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASLDED
Subjt:  EEEEDENDDEGKLMGSASFETSEEVQLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASLDED

A0A1S3CFK5 DNA topoisomerase 2

0.0e+00

96.2

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Query:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MVVEKKRPLQNSN ANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEN+KMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFS+EFVIETADGRRLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVV
        PIITKCK+GDNWTRVTFKPDL KFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPV+SFQDYVDLYLKSASS QAEPPKRYHI+PNERWEIVV
Subjt:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIAN+VMTAVNKKNKNANVKAHNVK+YLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLR
        ENKEIQYIKQILGLQQGKEYNNA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYE+WKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
        RFLFP+DDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRML+GETMLPMDPWYRGFSGTIEKTATKEGGTTYT+S
Subjt:  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKH  DKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPK
        TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELC+DRDKLKGEVDDLRKATPKSLWLNDLD LEKELDE+DRNDAQTMELRKQQR+KAN DLKPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPK

Query:  VSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETEV
        +SRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAV D+D+DDEVLELKDRLAAYKIESSPEPSEVSAMETEV
Subjt:  VSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETEV

Query:  QEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSGI
        QEV  QAAKKKEPSKRAPAKKKTTAKSAQISISDD++D DFEIKEVDP AAKKGGGR   GGRKAAA N KTTK PAAG KLGQKLITQMLEP AENSGI
Subjt:  QEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSGI

Query:  SPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEV---QLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASLDED
        SPEKKVRKIRASPFNKKSGSLLGR I EEEED  +DEGK+MGSAS ETSEEV   Q A GRSRRANR TQVRYVLSDSD E  SQDSDFDEDEASLDED
Subjt:  SPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEV---QLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASLDED

A0A5A7TZH5 DNA topoisomerase 2

0.0e+00

96.2

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Query:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MVVEKKRPLQNSN ANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEN+KMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFS+EFVIETADGRRLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVV
        PIITKCK+GDNWTRVTFKPDL KFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPV+SFQDYVDLYLKSASS QAEPPKRYHI+PNERWEIVV
Subjt:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIAN+VMTAVNKKNKNANVKAHNVK+YLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLR
        ENKEIQYIKQILGLQQGKEYNNA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYE+WKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
        RFLFP+DDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRML+GETMLPMDPWYRGFSGTIEKTATKEGGTTYT+S
Subjt:  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKH  DKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPK
        TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELC+DRDKLKGEVDDLRKATPKSLWLNDLD LEKELDE+DRNDAQTMELRKQQR+KAN DLKPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPK

Query:  VSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETEV
        +SRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAV D+D+DDEVLELKDRLAAYKIESSPEPSEVSAMETEV
Subjt:  VSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETEV

Query:  QEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSGI
        QEV  QAAKKKEPSKRAPAKKKTTAKSAQISISDD++D DFEIKEVDP AAKKGGGR   GGRKAAA N KTTK PAAG KLGQKLITQMLEP AENSGI
Subjt:  QEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSGI

Query:  SPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEV---QLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASLDED
        SPEKKVRKIRASPFNKKSGSLLGR I EEEED  +DEGK+MGSAS ETSEEV   Q A GRSRRANR TQVRYVLSDSD E  SQDSDFDEDEASLDED
Subjt:  SPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEV---QLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASLDED

A0A6J1F3D6 DNA topoisomerase 2

0.0e+00

90.22

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Query:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSNAANVDS+PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYEN+KMVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFS+EFVIETADGRRLKKYKQVF+DNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVV
        PIITKCK+GDNWT+VTFKPDL KFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPV+SFQDYVD YLKSA++ Q EPPKRYHIRPNERWEIVV
Subjt:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHV+YITNQIAN+VMT VNKKNKNANVKAHNVKSYLWVFINALIDNP+FDSQTKETLT R +SFGSACELTPDFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLR
        ENKEIQYIKQILGLQQGKEYNNA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYEAWK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD++DGEAIELAFSKKKIE+RKNWLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
        RFLFP+DDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRNVRRML GE MLPMDPWYRGFSGTIEKTATKEGGT+YTVS
Subjt:  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRI ELPVRRWT+DYKDFLDSVTRV++K+DKDKEKAAKDPFIEQADHHSDDK VSIDVHLTEENM+LA+QEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEF+EKRKR LL+NLE ELLKLENKVRFILAVVN EI VSNR++VDLFHELQ KGFTPFPKKTKSVEPE+AGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPK
        TDEAEESPEVVKGER+SDYEYLLAL IGTLTIEKVQELC++RDK KGEV++LRKATPKSLWL DLDYLEKELDEMDRNDAQ  E+RKQQR K N D+KPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPK

Query:  VSRNAPKAPRNSKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETE
        +SRNAPKAPRNSKKTSN ET+TESMD TT SSTTTEVANNPVVKPKGKAAPRKAPA KKGK AVLDDD+DDEVLELKDRLAAYK+ESSPEPSEVSAMETE
Subjt:  VSRNAPKAPRNSKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETE

Query:  VQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSG
        V +V Q AAKKKEPSKRA AKKKTTAKSAQ  ISDD +DGDFEIKE+ PPAAKKGGGR       A A  +KTTK     A+LGQKLITQMLEP  ENSG
Subjt:  VQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSG

Query:  ISPEKKVRKIRASPFNKKSGSLLGRTIGEEEE--DENDDEGKLMGSASFETSEE----VQLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASL
        ISPEKKVRKIR SPFNKKSGS+LGR IGEEEE  +E  +EGK+MGSAS ET++E    V LARGRS+R NR TQVRYV+SDSD E   +DSDFDE EA+L
Subjt:  ISPEKKVRKIRASPFNKKSGSLLGRTIGEEEE--DENDDEGKLMGSASFETSEE----VQLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASL

Query:  DED
        DED
Subjt:  DED

A0A6J1F9E0 DNA topoisomerase 2

0.0e+00

90.22

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Query:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSNAANVDS+PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYEN+KMVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFS+EFVIETADGRRLKKYKQVF+DNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVV
        PIITKCK+GDNWT+VTFKPDL KFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPV+SFQDYVD YLKSA++ Q EPPKRYHIRPNERWEIVV
Subjt:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHV+YITNQIAN+VMT VNKKNKNANVKAHNVKSYLWVFINALIDNP+FDSQTKETLT R +SFGSACELTPDFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLR
        ENKEIQYIKQILGLQQGKEYNNA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYEAWK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD++DGEAIELAFSKKKIE+RKNWLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
        RFLFP+DDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRNVRRML GE MLPMDPWYRGFSGTIEKTATKEGGT+YTVS
Subjt:  RFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRI ELPVRRWT+DYKDFLDSVTRV++K+DKDKEKAAKDPFIEQADHHSDDK VSIDVHLTEENM+LA+QEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEF+EKRKR LL+NLE ELLKLENKVRFILAVVN EI VSNR++VDLFHELQ KGFTPFPKKTKSVEPE+AGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPK
        TDEAEESPEVVKGER+SDYEYLLAL IGTLTIEKVQELC++RDK KGEV++LRKATPKSLWL DLDYLEKELDEMDRNDAQ  E+RKQQR K N D+KPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPK

Query:  VSRNAPKAPRNSKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETE
        +SRNAPKAPRNSKKTSN ET+TESMD TT SSTTTEVANNPVVKPKGKAAPRKAPAKK+GK AVLDDD+DDEVLELKDRLAAYK+ESSPEPSEVSAMETE
Subjt:  VSRNAPKAPRNSKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETE

Query:  VQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSG
        V +V Q AAKKKEPSKRA AKKKTTAKSAQ  ISDD +DGDFEIKE+ PPAAKKGGGR       A A  +KTTK     A+LGQKLITQMLEP  ENSG
Subjt:  VQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSG

Query:  ISPEKKVRKIRASPFNKKSGSLLGRTIGEEEE--DENDDEGKLMGSASFETSEE----VQLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASL
        ISPEKKVRKIR SPFNKKSGS+LGR IGEEEE  +E  +EGK+MGSAS ET++E    V LARGRS+R NR TQVRYV+SDSD E   +DSDFDE EA+L
Subjt:  ISPEKKVRKIRASPFNKKSGSLLGRTIGEEEE--DENDDEGKLMGSASFETSEE----VQLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASL

Query:  DED
        DED
Subjt:  DED

SwissProt top hits

e value

%identity

Alignment

O24308 DNA topoisomerase 2

0.0e+00

62.27

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Query:  KKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKV
        +KRPLQ SNAAN+      P KTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYEN++MVHR++SYVPGLYKIFDEILVNAADNKQRDPSMDS+KV
Subjt:  KKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKV

Query:  NIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSEPIIT
         ID E N +SV+NNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFS+EF+IETADGRRLKKYKQVF++NMG K EP+IT
Subjt:  NIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSEPIIT

Query:  KCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVVTLSE
        KCK  +NWT+VTFKPDLEKF M +LE+DVVALMKKRVLD+AGC GKTVKVELNG  +  +SF+DY DL+LK A   +  P  R H +  +RWEI ++LS+
Subjt:  KCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVVTLSE

Query:  GQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNVATKS
        GQFQQVSFVN IATIKGGTHV+YITNQI  ++M  VNKK K+ANVKAH VK++LWVF+N+LIDNP+FDSQTKETLT R  SFGS C++    LK+V  KS
Subjt:  GQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNVATKS

Query:  GIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKE
        GI+D++LSW +FKQSKDLKKTDG KT+++ G  K EDAN AGG+NSEKCTLILTEGDSAKALAMAGL VVGRD YGVFPLRGKLLNVREASSKQI +N+E
Subjt:  GIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKE

Query:  IQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLRGNAS
        IQ IK+ILGLQQ KEY N ++LRYGHLMIM DQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEF TP+++A+H N T+ SFY+MPEYEAWKE L  +A+
Subjt:  IQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLRGNAS

Query:  GWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSM
         W IKYYKGLGTST +EGREYF  L +H+KDFIW D+ DG AIELAFSKKK E RK W+R FEPGT  D   KLI Y DFVNKELILFS AD        
Subjt:  GWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSM

Query:  VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLF
                   LF SFK+   KE KV+QF GYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL PNGQFGT N GGKDHAS+RYIYT+LS VTR LF
Subjt:  VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLF

Query:  PRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVSGIIE
           DDKLL YLNEDG+SIEP WYMPIIP VLVNGSEGIGTGWSSY+PNYNPR+II NVRR+L GE ++PMDPWY+GF GTIEK+A KEGG  Y V+G + 
Subjt:  PRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVSGIIE

Query:  EVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDAN
        E+ + T RI ELP+R+WT DYK FL+S+T        D     KDP IE    + DD IV I++ +  E +   +QEGL KKFKLT+T+STSNMHLFDA 
Subjt:  EVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDAN

Query:  GVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETDEA
        G  KK+DTPEQILEEFFPLRL++YEK K  +L NL   LL L+NKVRFIL VVN EI VSNRKK +L  EL+ KGFTP P+K KS +P++AGA+++  E 
Subjt:  GVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETDEA

Query:  EESPE--------VVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANID
        +E  E         V+G    DY+ LL+LPIGTLT+E VQ+L  ++ + + E + L      SLWL DLD  EK+LDE+D   A+    R  Q  K    
Subjt:  EESPE--------VVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANID

Query:  LKPKVSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAM
           K ++  P+  +N+KK  +VE   ++      +         V KPKG+AAP+K           +  + +D++  L++RLAAY IESS E S+  AM
Subjt:  LKPKVSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAM

Query:  ETEVQEVQQQAAKKKEPSKRAPAKKKTTA----KSAQISISD-DDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSK------TTKPPAAGAK----
        E+E  EVQQ+AA KK+ +KR  AKKK++       +   ++D DD+D DFE  +      KK       GGRK AA N+K        K PAA  K    
Subjt:  ETEVQEVQQQAAKKKEPSKRAPAKKKTTA----KSAQISISD-DDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSK------TTKPPAAGAK----

Query:  ----LGQKLITQMLEPAAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEV-----QLARGRSRRANRTTQVRYVL
             GQKL+T ML+P AE +G SPEKKVRK+R SPFNKKSGS+LGR    ++     D      S +  + +EV     Q AR R +RANR TQ++Y L
Subjt:  ----LGQKLITQMLEPAAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEV-----QLARGRSRRANRTTQVRYVL

Query:  SDSDGEVASQDSDFDEDEASLDED
        S+S+ E   +DSD D + +  +ED
Subjt:  SDSDGEVASQDSDFDEDEASLDED

P08096 DNA topoisomerase 2

0.0e+00

47.57

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Query:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENE--KMVHRSISYVPGLYKIFDEILVNAADNKQRDPS
        M   ++ PL  +N  N +SN       +   YQ+ +  EH+L RPDTY+GSIE  T  +WV+++E  K+ +++++YVPGLYKIFDEI+VNAADNK RDP+
Subjt:  MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENE--KMVHRSISYVPGLYKIFDEILVNAADNKQRDPS

Query:  MDSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKK
        M+++KV +D E N IS++NNG G+P+EIH +EK+Y+PELIFG+LLTSSNYDD +KK TGGRNGYGAKL NIFS+EFV+ETAD  R+KKYKQ + DNM +K
Subjt:  MDSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKK

Query:  SEPIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEI
        SEP+IT  K  D +T++TFKPDL KF M  ++DD+V+++K+R+ D+AG + +T KV LN +R+ +  F+ YV++YL S +    EPP+  +   N+RW++
Subjt:  SEPIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEI

Query:  VVTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLK
           +S+GQF+QVSFVN I+TI+GGTHV Y+ N+I + +   V K+NK A VKA  +K+Y+ VF+N  I+NPSFDSQTKETLT + ++FGS C L+  FLK
Subjt:  VVTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLK

Query:  NVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ
         +  KS +++ VL +   K  + L K DG    +I+G+ KLEDAN AG K S KC LILTEGDSAK+LA++GL VVGRD+YGVFPLRGKLLNVREAS  Q
Subjt:  NVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ

Query:  ITENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKES
        I  NKEIQ IK+I+G    K Y + + LRYGHLMIMTDQDHDGSHIKGL+IN++ S +PSLL++P FL++FITPI+K T  N  V +FYT+PEYE WKE+
Subjt:  ITENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKES

Query:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQ
           N  GW IKYYKGLGTS   + + YF  L +H K F    + D E IE+AF+KKK + RK WLR + PG ++D T   I   DF+N+ELI FSMAD  
Subjt:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQ

Query:  RSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN
        RSIPS+VDGLKPGQRK+++  FKRN + E KVS+ +GYV+  +AYHHGE S+  TI+ +AQ+FVGSNNINLL+PNGQFGTR+ GGK+ ++SRY+ T LS 
Subjt:  RSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN

Query:  VTRFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYT
        + R LF  +DD+LLNY N++GQ IEP +Y+PI+P VLVNG+EGIGTGWS+++PNYNP+DI  N+R ML GE +  M PWYRGF G+I K A       Y 
Subjt:  VTRFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYT

Query:  VSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNM
        +SGII ++ +  + I ELP+R WT D K++L++      K  K         FI   + H  +  V  +V LTE  M  A+ E L+ KFKL+ T +TSNM
Subjt:  VSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNM

Query:  HLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPF--PKKTKSVEPEIAG
          FDA+G IKKYD+ E IL EF+ +RL  Y++RK  +++ LE    +  N+ RFI  ++  E+ VS +KK DL  EL+ K F P   PKK   V+ E+  
Subjt:  HLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPF--PKKTKSVEPEIAG

Query:  ASNETDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDE-MDRNDAQTMELRKQQREKAN-
          N   E E+S +V + E    Y YLL++P+ +LT E+  EL   +D++  E+D L K TPK LWL+DLD  E   ++ MD    + +E  +  R+  N 
Subjt:  ASNETDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDE-MDRNDAQTMELRKQQREKAN-

Query:  IDLKPKVSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSP--EPSE
           KP+      + PR    +S+   V +   +    +TT      ++    + A  K P +K     ++  +++   L +++     +I  SP  + S+
Subjt:  IDLKPKVSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSP--EPSE

Query:  VSAMETEVQEVQQQAAKKKEPSKR----APAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAA
                Q V  + A  K+P K+    A  + + T K    +I   D++ D     + P             G+KA++
Subjt:  VSAMETEVQEVQQQAAKKKEPSKR----APAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAA

P11388 DNA topoisomerase 2-alpha

0.0e+00

46.83

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Query:  MVVEKKRPL-QNSNAANVDSNPAGPKK-TIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMV-HRSISYVPGLYKIFDEILVNAADNKQRDP
        M V   +P+ +N     +  N    K+ ++E +YQKK+QLEHILLRPDTY+GS+E  TQ +WVY+ +  + +R +++VPGLYKIFDEILVNAADNKQRDP
Subjt:  MVVEKKRPL-QNSNAANVDSNPAGPKK-TIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMV-HRSISYVPGLYKIFDEILVNAADNKQRDP

Query:  SMDSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGK
         M  ++V ID E N IS++NNG G+PV  H+ EK+YVP LIFG LLTSSNYDD EKK TGGRNGYGAKL NIFS++F +ETA     K +KQ + DNMG+
Subjt:  SMDSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGK

Query:  KSEPIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWE
          E +  K  +G+++T +TF+PDL KF M  L+ D+VALM +R  D+AG   K VKV LNG ++PV+ F+ YVD+YLK          K  H + N RWE
Subjt:  KSEPIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWE

Query:  IVVTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNK-NANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDF
        + +T+SE  FQQ+SFVN IAT KGG HV+Y+ +QI   ++  V KKNK    VKAH VK+++W+F+NALI+NP+FDSQTKE +T +  SFGS C+L+  F
Subjt:  IVVTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNK-NANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDF

Query:  LKNVATKSGIMDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREAS
        +K  A   GI++S+L+WV FK    L KK    K  +I GI KL+DAN AGG+NS +CTLILTEGDSAK LA++GLGVVGRD YGVFPLRGK+LNVREAS
Subjt:  LKNVATKSGIMDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREAS

Query:  SKQITENKEIQYIKQILGLQQGKEY---NNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEY
         KQI EN EI  I +I+GLQ  K Y   ++ + LRYG +MIMTDQD DGSHIKGLLINFIH  WPSLLR   FL EFITPIVK + KN   ++FY++PE+
Subjt:  SKQITENKEIQYIKQILGLQQGKEY---NNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEY

Query:  EAWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFE-----------PGTHL-DQTGKLIK
        E WK S   N   W +KYYKGLGTSTSKE +EYF  + +H+  F +    D  AI LAFSKK+I+DRK WL  F            P  +L  QT   + 
Subjt:  EAWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFE-----------PGTHL-DQTGKLIK

Query:  YSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRN
        Y+DF+NKELILFS +D +RSIPSMVDGLKPGQRK+LF  FKRN  +E KV+Q +G V+E S+YHHGE SL  TII +AQ+FVGSNN+NLL P GQFGTR 
Subjt:  YSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRN

Query:  HGGKDHASSRYIYTKLSNVTRFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRG
        HGGKD AS RYI+T LS++ R LFP  DD  L +L +D Q +EP WY+PIIP VL+NG+EGIGTGWS  +PN++ R+I+ N+RR+++GE  LPM P Y+ 
Subjt:  HGGKDHASSRYIYTKLSNVTRFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRG

Query:  FSGTIEKTATKEGGTTYTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQ
        F GTIE+ A  +    Y +SG +  ++ TT+ I ELPVR WT  YK+      +V        EK    P I     +  D  V   V +TEE +  A +
Subjt:  FSGTIEKTATKEGGTTYTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQ

Query:  EGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGF
         GL K FKL T+++ ++M LFD  G +KKYDT   IL +FF LRL++Y  RK  LL  L  E  KL N+ RFIL  ++ +I + N+ K +L   L  +G+
Subjt:  EGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGF

Query:  TPFPKKTKSVEPEIAGASNETDEAEESPEVVKGERISD----YEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMD
           P K      +      E +E++   E  K + ++D    + YLL +P+  LT EK  ELC  R++ + E+D L++ +P  LW  DL    +EL+ ++
Subjt:  TPFPKKTKSVEPEIAGASNETDEAEESPEVVKGERISD----YEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMD

Query:  RNDAQTMEL---------RKQQREKANIDLKPKVSRNAPK---------APRNSKKTSNVETVTE------SMDTTYSSTTTEVANNPVVKPKGKAAPRK
          + Q  ++         + ++ + A +   P+  R  P+           +N KK  N  T          ++        +    P  K K +     
Subjt:  RNDAQTMEL---------RKQQREKANIDLKPKVSRNAPK---------APRNSKKTSNVETVTE------SMDTTYSSTTTEVANNPVVKPKGKAAPRK

Query:  APAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDD---NDGDFEIKEVDPP
         P KK  K     D E D               S     +V   ET             EP + A   K T    +    SD D   +D DF   +  PP
Subjt:  APAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDD---NDGDFEIKEVDPP

Query:  AAK
          K
Subjt:  AAK

P30182 DNA topoisomerase 2

0.0e+00

63.23

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Query:  KRPLQNSNAANVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNAANV   PA  +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ LWVYE ++MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNAANVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFS+EF+IETADG+RLKKYKQVF +NMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPP-KRYHIRPNERWEIV
        P+ITKC   +NWT+VTFKPDL+KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PV+SF DYVDLYL +A+  + E P  R   + N+RWE+ 
Subjt:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPP-KRYHIRPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKN
        V+LSEGQFQQVSFVN IATIKGGTHV+Y+T+QI N ++ AVNKKNKNANVKAHNVK++LWVF+NALIDNP+FDSQTKETLT R +SFGS CEL+ DFLK 
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKN

Query:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYEAWKE
        T NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT K GT  VLSFY+MPEYE WKE
Subjt:  TENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYEAWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADL
        SL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ    + YSDFVNKELILFSMADL
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADL

Query:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTY
         VTR LFP+DDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I+ NVRR+L GE+M+PMDPWYRGF GTIEKTA+KEGG TY
Subjt:  NVTRFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTY

Query:  TVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSN
        T++G+ EEV +TT+RI ELP+RRW  DYK+FL S+     K D         PF +    ++D+K V  D+ L+EENML A QEG  KKFKLTTT++TSN
Subjt:  TVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSN

Query:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGA
        MHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  ++ N+E+ELLKLENK RFILAV++ EI V+ RKK D+  +L+ KGFTPFP+K +SVE  IAGA
Subjt:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGA

Query:  SNETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMEL--RKQ
         ++ D AEE  E++            S+Y+YLLA+ I +LTIEKV+EL +DRDK+   V D++K TPKSLWL+DL+ L+KEL+++D  DAQ  +     Q
Subjt:  SNETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMEL--RKQ

Query:  QREKANIDLKPKVSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGK-AAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESS
        ++ +A      KV R APK P   KKT+   + +E+ + +YS+  T+     VVKPK +  A +KA   +  +A+    D D+ V E+         +  
Subjt:  QREKANIDLKPKVSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGK-AAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESS

Query:  PEPSEVSAMETEVQEVQQQAAKKKEPSKRAPAKKKTTAKSAQ-ISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKL
           +     E E+ ++ Q+ A+    S  APA    TA++++ I++ DDD+D   E+  V     KK       GGRK AA  +K  KPPAA  K G++ 
Subjt:  PEPSEVSAMETEVQEVQQQAAKKKEPSKRAPAKKKTTAKSAQ-ISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKL

Query:  I--TQMLEPAAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEVQLARGRSRRANRTTQVRYVLSDSDGEVASQDS
        +  T++L       G+SPEKKVRK+R+SPFNKKS S++ R    +EE+ +++   + G++S E S     A  R +RANR  ++ YVLSDS+ E A+ DS
Subjt:  I--TQMLEPAAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEVQLARGRSRRANRTTQVRYVLSDSDGEVASQDS

Query:  DFDEDEASLDED
        +FD+ E   D++
Subjt:  DFDEDEASLDED

Q55BP5 Probable DNA topoisomerase 2

0.0e+00

47.03

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Query:  EKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVK
        +K     N N     ++ A   K+IEE+YQKK  L+ ILLRPDTY+GS E+  + LWV+E+++MVHR +S+VPG+YKIFDEILVNAADNKQR+ +M  +K
Subjt:  EKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVK

Query:  VNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSEPII
        V ID E+  ISV N+G G+P+++H E K+Y+PELIFG+LLTSS+YDD+EK+ TGGRNG+GAKL NIFS++F++E AD +  K YKQ F +NM  K +P I
Subjt:  VNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSEPII

Query:  TKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVVTLS
        T  ++  ++T++TF P+L++F M   +DD+VAL+ KRV D+AGC   T+KV LN + + +RSF+ Y++LY       +   PK Y+ + ++RWE+ VTLS
Subjt:  TKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVVTLS

Query:  -EGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNK-NANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNVA
         E QF QVSFVN I T+KGGTHV +  + I   +   VNKKNK +A++K   +K++L VF+N LI+NP FDSQTKETLT + +SFGS CE +  F+K V 
Subjt:  -EGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNK-NANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNVA

Query:  -TKSGIMDSVLSWVNFKQSKDLKK--TDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ
         +KSGI+ S+L +  FK    LK+  + G K  K+S I KL+DAN AGG  SE CTLILTEGDSAK+LA AG+ VVG+D YG FPL+GKLLNVR+ S+K 
Subjt:  -TKSGIMDSVLSWVNFKQSKDLKK--TDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ

Query:  ITENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKES
        +  N EI  I  ILGL+ GK Y     LRYGHLMIMTDQDHDGSHIKGL+IN +H FWP+LLR+P FLVEFITPIVK    N   +SFYTMPE+  W+E+
Subjt:  ITENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKES

Query:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTG-KLIKYSDFVNKELILFSMADL
           N  GW +KYYKGLGTST  EG+EYF  L +HK DF W D+   + IELAFSK + +DRK W+ +   GT L+Q G K + YSDF+NKEL+LFS+AD 
Subjt:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTG-KLIKYSDFVNKELILFSMADL

Query:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        +RSIP++VDGLK   RK L+  FKRN  KE KV+Q  GYVSEHSAYHHGE SL STI+GMAQ+FVGSNNINLL P G +GTR  GGKD +S+RYI+T+L+
Subjt:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIE-KTATKEGGTT
        ++ R ++  DDD +L+ + +DG+ ++P +Y+P+IP +LVNG  GIGTGWSS +PNYNPRD+I+N+R  ++G+ + P+ PWYRGF G+IE    +K  G  
Subjt:  NVTRFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIE-KTATKEGGTT

Query:  YTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSV----TRVASKHDKDKEKA------AKDPFIEQADHHSDD----KIVSIDV------------HL
        Y   GI +++SD    I ELP+  WT DY++ LD +    TR   K +K+K+ A      AK    +++    DD    K+    V            H 
Subjt:  YTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSV----TRVASKHDKDKEKA------AKDPFIEQADHHSDD----KIVSIDV------------HL

Query:  TEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVD
          + +    +  ++K FKL +T++ +NM +FD  G I+++ T   + E FFPLR++ Y+ RK  L + L  E  +L NK RFILAVVN+E+ +SN KKVD
Subjt:  TEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVD

Query:  LFHELQAKGFTPFPKK--TKSVEPEIAGASNETDE------AEESPEVVKGERISD---YEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKS
        L ++L+   F     K   KS   +I    N  DE      ++E  +  + E+  D   Y+YLL+LP+ +LT+E+V++L  +RD  K E D L     + 
Subjt:  LFHELQAKGFTPFPKK--TKSVEPEIAGASNETDE------AEESPEVVKGERISD---YEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKS

Query:  LWLNDLDYLEKELDEMDRNDA----QTMELRKQQREKA---NIDLKPKVSRNAPKAPRNS--KKTSNVETVTESM----------DTTYSSTTTEVANN-
        ++  DLD LEK LD+ D  D     QT  L+K+ + KA      +  KV ++  +AP     K T  + T T+S           DTT +ST+T  ++N 
Subjt:  LWLNDLDYLEKELDEMDRNDA----QTMELRKQQREKA---NIDLKPKVSRNAPKAPRNS--KKTSNVETVTESM----------DTTYSSTTTEVANN-

Query:  -PVVKPKGKAAPRKAPAKKKGKAAVLDDD---EDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQEVQQQAAKKKEPSKRAPAKKKTT-----AKSAQI
         P+     K   +  PA KK     LD D   +DD V+  K +    K     E S+ S  E++ +  Q    +      +AP KK TT     A +++ 
Subjt:  -PVVKPKGKAAPRKAPAKKKGKAAVLDDD---EDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQEVQQQAAKKKEPSKRAPAKKKTT-----AKSAQI

Query:  SISDDDNDGDFEIK
         + DD +  D  IK
Subjt:  SISDDDNDGDFEIK

Arabidopsis top hits

e value

%identity

Alignment

AT3G10270.1 DNA GYRASE B1

8.8e-24

24.26

Show/hide

Query:  GLYKIFDEILVNAADNKQRDPSMDSVKVNIDV---EQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFS
        GL+ +  EIL NA D  Q           IDV     + +S+ +NG G+P ++H        E +   L     +         +GG +G G  + N  S
Subjt:  GLYKIFDEILVNAADNKQRDPSMDSVKVNIDV---EQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFS

Query:  SEF-VIETADGRRLKKYKQVFNDNMGKKSEPIIT-KC------KDGDNWTRVTFKPDLEKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVP
            VI   DG    +++Q ++     + +P+ T  C        G   T + F PD E F      + + +A   + +  L   +  ++K E +     
Subjt:  SEF-VIETADGRRLKKYKQVFNDNMGKKSEPIIT-KC------KDGDNWTRVTFKPDLEKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVP

Query:  VRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVVTLSEGQFQ---------QVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHN
        V S   Y     +  S +  +  K  H     R EI  +  +   Q          + + N I TI GGTH+E +   +    + ++ KK K   VK + 
Subjt:  VRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVVTLSEGQFQ---------QVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHN

Query:  VKSYLWV-------------------------------------FINALIDNPSFDSQTKETL----------TKRANSFGSACELTPDFLKNVATKSGI
        + S  W+                                      ++  + NP F+ QTK  L                     EL PD L+++ +KS  
Subjt:  VKSYLWV-------------------------------------FINALIDNPSFDSQTKETL----------TKRANSFGSACELTPDFLKNVATKSGI

Query:  MDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEI
        +++  + +  K++++L ++    K+  + G  KL D +      SE   + + EGDSA   A  G     R F  + PLRGK+LN+       + +N+EI
Subjt:  MDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEI

Query:  QYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLRGNASG
        Q +   LGL    E  N   LRY  ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K   +       Y     +    S  GNAS 
Subjt:  QYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLRGNASG

Query:  WSIKYYKGLG
        ++I+ +KGLG
Subjt:  WSIKYYKGLG

AT3G23890.1 topoisomerase II

0.0e+00

63.23

Show/hide

Query:  KRPLQNSNAANVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNAANV   PA  +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ LWVYE ++MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNAANVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFS+EF+IETADG+RLKKYKQVF +NMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPP-KRYHIRPNERWEIV
        P+ITKC   +NWT+VTFKPDL+KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PV+SF DYVDLYL +A+  + E P  R   + N+RWE+ 
Subjt:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPP-KRYHIRPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKN
        V+LSEGQFQQVSFVN IATIKGGTHV+Y+T+QI N ++ AVNKKNKNANVKAHNVK++LWVF+NALIDNP+FDSQTKETLT R +SFGS CEL+ DFLK 
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKN

Query:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYEAWKE
        T NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT K GT  VLSFY+MPEYE WKE
Subjt:  TENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYEAWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADL
        SL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ    + YSDFVNKELILFSMADL
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADL

Query:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTY
         VTR LFP+DDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I+ NVRR+L GE+M+PMDPWYRGF GTIEKTA+KEGG TY
Subjt:  NVTRFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTY

Query:  TVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSN
        T++G+ EEV +TT+RI ELP+RRW  DYK+FL S+     K D         PF +    ++D+K V  D+ L+EENML A QEG  KKFKLTTT++TSN
Subjt:  TVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSN

Query:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGA
        MHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  ++ N+E+ELLKLENK RFILAV++ EI V+ RKK D+  +L+ KGFTPFP+K +SVE  IAGA
Subjt:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGA

Query:  SNETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMEL--RKQ
         ++ D AEE  E++            S+Y+YLLA+ I +LTIEKV+EL +DRDK+   V D++K TPKSLWL+DL+ L+KEL+++D  DAQ  +     Q
Subjt:  SNETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMEL--RKQ

Query:  QREKANIDLKPKVSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGK-AAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESS
        ++ +A      KV R APK P   KKT+   + +E+ + +YS+  T+     VVKPK +  A +KA   +  +A+    D D+ V E+         +  
Subjt:  QREKANIDLKPKVSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGK-AAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESS

Query:  PEPSEVSAMETEVQEVQQQAAKKKEPSKRAPAKKKTTAKSAQ-ISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKL
           +     E E+ ++ Q+ A+    S  APA    TA++++ I++ DDD+D   E+  V     KK       GGRK AA  +K  KPPAA  K G++ 
Subjt:  PEPSEVSAMETEVQEVQQQAAKKKEPSKRAPAKKKTTAKSAQ-ISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKL

Query:  I--TQMLEPAAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEVQLARGRSRRANRTTQVRYVLSDSDGEVASQDS
        +  T++L       G+SPEKKVRK+R+SPFNKKS S++ R    +EE+ +++   + G++S E S     A  R +RANR  ++ YVLSDS+ E A+ DS
Subjt:  I--TQMLEPAAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEVQLARGRSRRANRTTQVRYVLSDSDGEVASQDS

Query:  DFDEDEASLDED
        +FD+ E   D++
Subjt:  DFDEDEASLDED

AT3G23890.2 topoisomerase II

0.0e+00

63.53

Show/hide

Query:  KRPLQNSNAANVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNAANV   PA  +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ LWVYE ++MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNAANVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFS+EF+IETADG+RLKKYKQVF +NMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPP-KRYHIRPNERWEIV
        P+ITKC   +NWT+VTFKPDL+KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PV+SF DYVDLYL +A+  + E P  R   + N+RWE+ 
Subjt:  PIITKCKDGDNWTRVTFKPDLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPP-KRYHIRPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKN
        V+LSEGQFQQVSFVN IATIKGGTHV+Y+T+QI N ++ AVNKKNKNANVKAHNVK++LWVF+NALIDNP+FDSQTKETLT R +SFGS CEL+ DFLK 
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKN

Query:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYEAWKE
        T NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT K GT  VLSFY+MPEYE WKE
Subjt:  TENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYEAWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADL
        SL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ    + YSDFVNKELILFSMADL
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADL

Query:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTY
         VTR LFP+DDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I+ NVRR+L GE+M+PMDPWYRGF GTIEKTA+KEGG TY
Subjt:  NVTRFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTY

Query:  TVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSN
        T++G+ EEV +TT+RI ELP+RRW  DYK+FL S+     K D         PF +    ++D+K V  D+ L+EENML A QEG  KKFKLTTT++TSN
Subjt:  TVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSN

Query:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGA
        MHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  ++ N+E+ELLKLENK RFILAV++ EI V+ RKK D+  +L+ KGFTPFP+K +SVE  IAGA
Subjt:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGA

Query:  SNETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMEL--RKQ
         ++ D AEE  E++            S+Y+YLLA+ I +LTIEKV+EL +DRDK+   V D++K TPKSLWL+DL+ L+KEL+++D  DAQ  +     Q
Subjt:  SNETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMEL--RKQ

Query:  QREKANIDLKPKVSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGK-AAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESS
        ++ +A      KV R APK P   KKT+   + +E+ + +YS+  T+     VVKPKG+  A +KAPA  K       + E+DE+L+L  RLA Y   S+
Subjt:  QREKANIDLKPKVSRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGK-AAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESS

Query:  PEPSEVSAMETEVQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLI
        P  S                              KT   S  I++ DDD+D   E+  V     KK       GGRK AA  +K  KPPAA  K G++ +
Subjt:  PEPSEVSAMETEVQEVQQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLI

Query:  --TQMLEPAAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEVQLARGRSRRANRTTQVRYVLSDSDGEVASQDSD
          T++L       G+SPEKKVRK+R+SPFNKKS S++ R    +EE+ +++   + G++S E S     A  R +RANR  ++ YVLSDS+ E A+ DS+
Subjt:  --TQMLEPAAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEDENDDEGKLMGSASFETSEEVQLARGRSRRANRTTQVRYVLSDSDGEVASQDSD

Query:  FDEDEASLDED
        FD+ E   D++
Subjt:  FDEDEASLDED

AT5G04130.1 DNA GYRASE B2

1.6e-28

24.84

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Query:  EMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVE-QNCISVFNNGDGVPVEIHQ
        E  Q    L+ +  RP  Y+GS                         GL+ +  EIL NA D  Q   +    KV++ +     +SV +NG G+P ++H 
Subjt:  EMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVE-QNCISVFNNGDGVPVEIHQ

Query:  EEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSEPIIT-KCK------DGDNWTRVTFKP
          K    E +   L     +  T      +GG +G G  + N  S    +E +  R   ++KQ ++     + +PI T  C+       G   T + F P
Subjt:  EEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSEPIIT-KCK------DGDNWTRVTFKP

Query:  DLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQ-----------DYVDLYLKSASSIQAEPPKRYHIRPNERWEIVVTLSEGQFQ
        D E F  T +E D   +   R+ +LA  L   V + L  +       Q           +YV       + I      R  I      ++ +      + 
Subjt:  DLEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQ-----------DYVDLYLKSASSIQAEPPKRYHIRPNERWEIVVTLSEGQFQ

Query:  --QVSFVNGIATIKGGTHVEYITNQIANFVMTAVNK----KNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETL----------TKRANSFGSACEL
           + + N I TI GGTH+E +   +   + T   K    K K+ ++   +V+  L   ++  + NP F+ QTK  L                     EL
Subjt:  --QVSFVNGIATIKGGTHVEYITNQIANFVMTAVNK----KNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETL----------TKRANSFGSACEL

Query:  TPDFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNV
         PD L+++ +KS  +++  + +  K++++L ++    K+  + G  KL D +    + SE   + + EGDSA   A  G     R F  + PLRGK+LN+
Subjt:  TPDFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNV

Query:  REASSKQITENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPE
               + +N+EIQ +   LGL    E      LRY  ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K   +       Y   +
Subjt:  REASSKQITENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPE

Query:  YEAWKESLRGNASGWSIKYYKGLG
         +    +   NAS ++I+ +KGLG
Subjt:  YEAWKESLRGNASGWSIKYYKGLG

Sequences

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CDS sequence

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ATGGTTGTCGAAAAGAAACGGCCACTTCAGAACAGCAACGCCGCCAATGTCGACTCCAATCCGGCAGGTCCAAAGAAAACAATCGAAGAAATGTACCAAAAGAAGTCTCA
GCTCGAGCACATTCTTCTCAGGCCCGATACCTATGTCGGATCTATTGAAAAGCATACCCAAAACCTCTGGGTTTACGAGAATGAAAAAATGGTCCACCGATCAATCTCTT
ACGTGCCTGGTCTTTACAAGATCTTTGATGAAATCTTGGTCAATGCCGCAGATAATAAGCAGAGAGACCCTTCCATGGATTCTGTCAAGGTCAATATTGATGTCGAACAG
AACTGTATCAGTGTTTTCAACAATGGAGATGGAGTTCCGGTTGAAATTCATCAGGAAGAGAAGGTTTATGTGCCTGAGTTGATCTTTGGACATTTGTTGACTAGTAGTAA
CTACGATGATACCGAAAAGAAAACCACTGGTGGACGGAATGGGTATGGTGCGAAACTTACCAATATTTTTTCTTCTGAATTTGTGATCGAAACGGCTGATGGAAGGCGCC
TGAAGAAGTATAAGCAGGTATTCAATGATAACATGGGTAAAAAATCAGAGCCGATTATAACAAAGTGCAAGGATGGTGACAATTGGACCAGAGTAACTTTTAAACCAGAC
CTGGAAAAATTTAACATGACCCATCTTGAAGATGATGTTGTTGCACTGATGAAAAAGAGAGTCTTGGATTTGGCTGGATGCCTTGGTAAAACCGTGAAGGTTGAGCTGAA
TGGACAAAGGGTCCCTGTAAGATCATTTCAAGATTATGTAGATCTCTACCTCAAATCAGCATCCTCAATCCAGGCGGAACCTCCCAAAAGGTATCACATTAGGCCTAATG
AGAGATGGGAAATTGTGGTGACCTTAAGTGAGGGCCAGTTCCAACAGGTCAGCTTTGTGAACGGGATTGCAACAATCAAGGGTGGGACTCATGTTGAATACATCACTAAT
CAAATAGCAAATTTTGTGATGACTGCTGTAAATAAGAAGAACAAAAATGCTAACGTGAAGGCTCATAATGTGAAGAGCTATTTGTGGGTTTTTATCAATGCTCTCATTGA
TAATCCATCCTTCGACTCCCAAACCAAGGAAACTTTGACAAAACGTGCAAACAGTTTCGGTTCTGCATGTGAACTTACGCCAGATTTTTTGAAGAATGTGGCCACAAAAT
CTGGAATTATGGACAGCGTTCTCTCATGGGTTAATTTCAAGCAAAGCAAAGATTTGAAGAAAACGGATGGAGCAAAAACAGAAAAGATTAGTGGTATCGAAAAGTTGGAG
GACGCCAATTGTGCTGGAGGGAAGAACTCAGAAAAATGTACCTTAATTTTGACGGAAGGAGATTCGGCTAAGGCCCTTGCAATGGCTGGGCTCGGTGTAGTAGGACGAGA
CTTTTATGGTGTATTCCCACTCAGAGGTAAATTGCTCAATGTGAGGGAAGCAAGTAGTAAACAAATCACAGAGAATAAAGAAATTCAGTACATCAAGCAAATTCTTGGAC
TTCAGCAAGGGAAGGAATACAACAATGCTAGGGCTTTGAGATACGGTCATTTGATGATTATGACCGATCAGGACCACGATGGCTCACACATTAAAGGACTCTTGATCAAC
TTTATTCATTCTTTTTGGCCTTCTCTCCTAAGAGTGCCATCGTTCTTGGTTGAATTCATAACGCCAATTGTCAAGGCTACTCATAAGAATGGAACTGTTTTATCTTTCTA
TACCATGCCCGAGTACGAAGCCTGGAAAGAGAGCTTGAGGGGCAATGCAAGTGGCTGGTCAATCAAGTACTATAAGGGGTTGGGAACAAGCACATCAAAAGAAGGAAGAG
AGTACTTTGAACAGCTGACAAAGCACAAGAAAGATTTTATTTGGCAAGATGATAATGACGGGGAGGCCATTGAGCTTGCTTTCAGTAAGAAGAAGATTGAAGATAGAAAG
AATTGGCTCCGTCAATTTGAGCCTGGTACCCATCTAGATCAGACAGGAAAATTGATAAAATACAGTGACTTCGTTAACAAGGAGCTTATATTATTTTCAATGGCTGATTT
ACAAAGGTCTATTCCGTCAATGGTTGATGGCCTTAAGCCTGGCCAAAGGAAGATCCTTTTCTGTTCTTTCAAGAGGAACTTTATCAAAGAAGCAAAGGTTTCACAATTTT
CCGGTTACGTATCTGAGCACTCTGCTTATCATCATGGTGAGCAGAGTCTTGCTAGTACCATCATTGGAATGGCACAGGACTTTGTTGGCAGTAACAACATTAATCTTCTT
CTACCAAATGGACAGTTTGGCACACGGAACCATGGAGGCAAAGATCATGCAAGTTCTAGGTACATTTACACTAAACTTTCAAATGTCACACGGTTCCTTTTCCCGAGAGA
TGATGACAAGCTTCTTAACTACTTAAATGAAGATGGCCAGTCGATTGAACCAACCTGGTATATGCCTATCATCCCAACCGTTCTTGTCAATGGAAGTGAAGGAATTGGAA
CTGGTTGGAGTTCATACGTTCCAAACTATAATCCTAGAGACATCATTAGAAATGTCAGACGCATGTTGGAGGGAGAAACGATGTTGCCAATGGATCCGTGGTATAGAGGT
TTTTCAGGAACTATAGAGAAAACTGCCACTAAAGAAGGAGGTACTACTTACACTGTTAGTGGAATTATAGAGGAAGTCAGCGATACGACGTTGAGAATAGTTGAATTGCC
AGTCCGCCGATGGACTAGTGACTACAAGGACTTTCTTGACTCTGTCACAAGAGTTGCATCAAAGCATGACAAAGATAAAGAAAAAGCAGCAAAAGATCCTTTTATTGAGC
AAGCTGATCACCACAGCGATGACAAAATTGTTTCCATTGATGTTCACTTAACAGAGGAAAACATGTTATTGGCCATCCAGGAAGGTTTGAAGAAGAAATTCAAACTAACT
ACAACTGTCAGCACTAGCAACATGCACCTGTTTGATGCAAATGGCGTCATTAAGAAATATGACACCCCAGAACAAATTCTTGAGGAATTTTTCCCCCTTAGACTTGAATT
CTACGAGAAAAGAAAGAGAATTCTTTTGGATAACCTTGAAATGGAGTTGCTTAAACTGGAAAACAAGGTGAGGTTCATTCTTGCTGTTGTGAATGAAGAGATAAAAGTAA
GCAATAGAAAAAAGGTTGATTTGTTCCACGAGCTTCAAGCGAAAGGCTTTACACCCTTTCCAAAGAAGACTAAATCTGTTGAGCCGGAGATTGCTGGGGCATCTAATGAA
ACTGATGAAGCAGAGGAGAGCCCGGAAGTGGTAAAAGGGGAACGAATTAGTGATTATGAGTATCTACTAGCTCTGCCAATTGGAACCTTGACCATCGAGAAGGTTCAGGA
GCTATGTAGTGATAGAGACAAGCTGAAAGGAGAAGTGGACGATTTGAGGAAGGCAACCCCCAAGTCTTTGTGGCTGAATGACCTTGATTATCTTGAGAAAGAGCTTGATG
AGATGGATAGAAATGATGCTCAGACAATGGAGTTAAGAAAACAACAGCGAGAGAAAGCAAATATCGATTTAAAGCCAAAAGTGTCAAGAAATGCACCAAAAGCTCCACGT
AACAGTAAGAAAACCAGCAATGTGGAAACTGTCACCGAAAGTATGGACACAACATATAGTTCTACAACAACTGAAGTTGCAAATAACCCGGTGGTGAAGCCGAAAGGCAA
AGCAGCTCCAAGAAAAGCTCCTGCTAAAAAGAAGGGTAAAGCAGCAGTTCTTGACGATGACGAAGATGACGAAGTCCTCGAGCTTAAAGATCGTCTTGCTGCCTATAAAA
TTGAGTCATCTCCTGAACCATCAGAAGTTTCAGCCATGGAAACTGAAGTGCAGGAAGTACAACAACAAGCGGCCAAGAAGAAAGAACCTAGCAAGAGAGCACCTGCCAAG
AAGAAAACTACTGCAAAGTCAGCTCAGATCTCCATTAGCGACGACGACAACGACGGAGATTTCGAAATAAAGGAAGTAGACCCTCCGGCAGCCAAGAAGGGAGGAGGAAG
AGGAGGAGGAGGAGGAAGAAAGGCAGCTGCAGGAAATAGCAAAACAACCAAGCCCCCTGCTGCAGGAGCGAAGTTGGGGCAGAAACTGATAACTCAAATGCTAGAACCAG
CAGCAGAGAACTCCGGCATCTCACCAGAGAAGAAAGTGAGGAAGATAAGAGCATCACCTTTCAACAAGAAAAGTGGCTCTTTATTGGGAAGAACAATAGGGGAAGAAGAA
GAGGATGAAAACGACGATGAAGGGAAGTTGATGGGTTCTGCTTCTTTCGAGACTAGTGAAGAAGTTCAGCTGGCGAGAGGGAGATCTCGGAGAGCAAACAGAACAACACA
GGTCAGGTATGTGCTTAGTGATTCAGATGGTGAGGTAGCTTCTCAGGATTCAGACTTCGATGAAGACGAAGCCAGCCTTGATGAAGATTGA

mRNA sequence

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Protein sequence

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MVVEKKRPLQNSNAANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENEKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQ
NCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSSEFVIETADGRRLKKYKQVFNDNMGKKSEPIITKCKDGDNWTRVTFKPD
LEKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSASSIQAEPPKRYHIRPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVEYITN
QIANFVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPDFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLE
DANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLIN
FIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYEAWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRK
NWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL
LPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPRDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRG
FSGTIEKTATKEGGTTYTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLT
TTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCSDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKANIDLKPKVSRNAPKAPR
NSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQEVQQQAAKKKEPSKRAPAK
KKTTAKSAQISISDDDNDGDFEIKEVDPPAAKKGGGRGGGGGRKAAAGNSKTTKPPAAGAKLGQKLITQMLEPAAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEE
EDENDDEGKLMGSASFETSEEVQLARGRSRRANRTTQVRYVLSDSDGEVASQDSDFDEDEASLDED

CSPI03G29600 (gene) of Cucumber (PI 183967) v1 genome