CuGenDBv2

Gene ID	CSPI03G37060
Organism	Cucumis sativus L. var. sativus cv. PI 183967 (Cucumber (PI 183967) v1)
Description	DNA topoisomerase
Genome location	Chr3:32120395..32133307
RNA-Seq Expression	CSPI03G37060
Synteny	CSPI03G37060
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0005634 - nucleus (cellular component) GO:0005694 - chromosome (cellular component) GO:0003677 - DNA binding (molecular function) GO:0008270 - zinc ion binding (molecular function) GO:0003917 - DNA topoisomerase type I activity (molecular function)
InterPro domains	IPR003602 - DNA topoisomerase, type IA, DNA-binding domain IPR034144 - DNA topoisomerase 3-like, TOPRIM domain IPR023406 - DNA topoisomerase, type IA, active site IPR023405 - DNA topoisomerase, type IA, core domain IPR013826 - DNA topoisomerase, type IA, central region, subdomain 3 IPR013825 - DNA topoisomerase, type IA, central region, subdomain 2 IPR013824 - DNA topoisomerase, type IA, central region, subdomain 1 IPR013497 - DNA topoisomerase, type IA, central IPR006171 - TOPRIM domain IPR003601 - DNA topoisomerase, type IA, domain 2 IPR000380 - DNA topoisomerase, type IA

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAA0043680.1 DNA topoisomerase 3-alpha isoform X1 [Cucumis melo var. makuwa]

0.0e+00

94.66

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Query:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK
        MSGGR ITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKW+SCDPVQLFHAPVHKFVPEDK
Subjt:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK

Query:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDAR-------------------
        LDIKRTLEQE+RR+QWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIH+AVQNLVQPNKWFADAVDAR                   
Subjt:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDAR-------------------

Query:  -------QEIDLRIGASFTRFQTLLLKDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCA
               QEIDLRIGASFTRFQTLLLKDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQ+HEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCA
Subjt:  -------QEIDLRIGASFTRFQTLLLKDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCA

Query:  VVFYEMCVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRL
        VVFYEMCVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRL
Subjt:  VVFYEMCVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRL

Query:  LDPESRLWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGST
        LDPES LWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGST
Subjt:  LDPESRLWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGST

Query:  IPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEH
        IPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPT+LGEALVMGYDDMGYNLWKP+LRAIMEH
Subjt:  IPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEH

Query:  EMKAVSEGTKRKDEVLASCLQQMKTCFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ
        EMKAVSEGTKRKDEVLASCLQQMK CFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQ+SDMVLKRNRDGNYMVGCLAFPQ
Subjt:  EMKAVSEGTKRKDEVLASCLQQMKTCFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ

XP_008443145.1 PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Cucumis melo]

0.0e+00

98.35

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Query:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK
        MSGGR ITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKW+SCDPVQLFHAPVHKFVPEDK
Subjt:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK

Query:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL
        LDIKRTLEQE+RR+QWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIH+AVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL
Subjt:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL

Query:  KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY
        KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQ+HEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY
Subjt:  KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPES LWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPT+LGEALVMGYDDMGYNLWKP+LRAIMEHEMKAVSEGTKRKDEVLASCLQQMK C
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC

Query:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ
        FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQ+SDMVLKRNRDGNYMVGCLAFPQ
Subjt:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ

XP_011652135.2 DNA topoisomerase 3-alpha isoform X1 [Cucumis sativus]

0.0e+00

99.85

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Query:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK
        MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK
Subjt:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK

Query:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL
        LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL
Subjt:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL

Query:  KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY
        KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY
Subjt:  KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLG+ALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC

Query:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ
        FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ
Subjt:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ

XP_016899727.1 PREDICTED: DNA topoisomerase 3-alpha isoform X2 [Cucumis melo]

0.0e+00

98.35

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Query:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK
        MSGGR ITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKW+SCDPVQLFHAPVHKFVPEDK
Subjt:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK

Query:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL
        LDIKRTLEQE+RR+QWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIH+AVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL
Subjt:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL

Query:  KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY
        KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQ+HEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY
Subjt:  KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPES LWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPT+LGEALVMGYDDMGYNLWKP+LRAIMEHEMKAVSEGTKRKDEVLASCLQQMK C
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC

Query:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ
        FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQ+SDMVLKRNRDGNYMVGCLAFPQ
Subjt:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ

XP_038904101.1 DNA topoisomerase 3-alpha isoform X1 [Benincasa hispida]

0.0e+00

96.7

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Query:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK
        MSGGR ITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMEL FEERYRKWHSCDPVQLFHAPV K VPEDK
Subjt:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK

Query:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL
        +DIKRTLEQE+RR QWL+LWLDCDREGENIAFEVVEVCTAVN HLNIKRAHFSALIERDIH+AVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQT+LL
Subjt:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL

Query:  KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY
        KDAFNIDSV DDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNS DGISTFSWTRGNLFDYTCAVVFYEMCVQE TATVVNVRRQETLKY
Subjt:  KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIV+EQQEHQIWGAYAQRLLDP S LWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKP+LRAIMEHEMKAVSEGTKRKDEVLA+CLQQMK+C
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC

Query:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ
        FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQ CGLCQDS+MVLKRNRDGNYMVGCLAFPQ
Subjt:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LBG7 DNA topoisomerase

0.0e+00

99.85

Show/hide

Query:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK
        MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK
Subjt:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK

Query:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL
        LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL
Subjt:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL

Query:  KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY
        KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY
Subjt:  KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC

Query:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ
        FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCL FPQ
Subjt:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ

A0A1S3B7B9 DNA topoisomerase

0.0e+00

98.35

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Query:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK
        MSGGR ITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKW+SCDPVQLFHAPVHKFVPEDK
Subjt:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK

Query:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL
        LDIKRTLEQE+RR+QWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIH+AVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL
Subjt:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL

Query:  KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY
        KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQ+HEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY
Subjt:  KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPES LWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPT+LGEALVMGYDDMGYNLWKP+LRAIMEHEMKAVSEGTKRKDEVLASCLQQMK C
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC

Query:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ
        FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQ+SDMVLKRNRDGNYMVGCLAFPQ
Subjt:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ

A0A1S4DUQ9 DNA topoisomerase

0.0e+00

98.35

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Query:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK
        MSGGR ITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKW+SCDPVQLFHAPVHKFVPEDK
Subjt:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK

Query:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL
        LDIKRTLEQE+RR+QWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIH+AVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL
Subjt:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL

Query:  KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY
        KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQ+HEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY
Subjt:  KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPES LWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPT+LGEALVMGYDDMGYNLWKP+LRAIMEHEMKAVSEGTKRKDEVLASCLQQMK C
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC

Query:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ
        FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQ+SDMVLKRNRDGNYMVGCLAFPQ
Subjt:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ

A0A5A7TKA3 DNA topoisomerase

0.0e+00

94.66

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Query:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK
        MSGGR ITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKW+SCDPVQLFHAPVHKFVPEDK
Subjt:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK

Query:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDAR-------------------
        LDIKRTLEQE+RR+QWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIH+AVQNLVQPNKWFADAVDAR                   
Subjt:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDAR-------------------

Query:  -------QEIDLRIGASFTRFQTLLLKDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCA
               QEIDLRIGASFTRFQTLLLKDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQ+HEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCA
Subjt:  -------QEIDLRIGASFTRFQTLLLKDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCA

Query:  VVFYEMCVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRL
        VVFYEMCVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRL
Subjt:  VVFYEMCVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRL

Query:  LDPESRLWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGST
        LDPES LWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGST
Subjt:  LDPESRLWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGST

Query:  IPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEH
        IPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPT+LGEALVMGYDDMGYNLWKP+LRAIMEH
Subjt:  IPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEH

Query:  EMKAVSEGTKRKDEVLASCLQQMKTCFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ
        EMKAVSEGTKRKDEVLASCLQQMK CFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQ+SDMVLKRNRDGNYMVGCLAFPQ
Subjt:  EMKAVSEGTKRKDEVLASCLQQMKTCFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ

A0A6J1IXM8 DNA topoisomerase

0.0e+00

94.3

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Query:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK
        M+GGR ITVLNVAEKPSVAKSVATILSRNQGLRVR+GRSRYNKIFEFNYAIRGQSCNM+VTSVTGHLMEL FEERYRKWHSCDPV+LF+APV K VPEDK
Subjt:  MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDK

Query:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL
        +DIKRTLEQE+RR QWLVLWLDCDREGENIAFEVVEVCT VN HLNIKRAHFSALIERDIH+AVQNLVQPNK+FADAVDARQEIDLRIGASFTRFQT+LL
Subjt:  LDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLL

Query:  KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY
        KDAFNIDSV DDRN+VLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNS DGISTFSWTRGNLFDYTCAVV YEMCV+ESTATVVNVRRQETLKY
Subjt:  KDAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIV+EQQEHQIWGAYAQRLLDP S LWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTY SGQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGY LWKP+LRA+MEHEMKAVSEG KRKDEVLA+CLQQMK+C
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTC

Query:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ
        FLDAR NKQKL EAMEVFFERSNGSGGDEN AVGEVVQ C LCQDSDMVLKRNRDGNYMVGCL FPQ
Subjt:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ

SwissProt top hits

e value

%identity

Alignment

C7J0A2 DNA topoisomerase 3-alpha

1.9e-305

74.17

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Query:  GGRSITVLNVAEKPSVAKSVATILSR-NQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDKL
        GG +I VLNVAEKPSVAKSVA ILSR + G+R R+GRSRYN++FEF+Y+I G++C+M+VTSVTGHLMEL F++R+R+WHSCDP  LFHAPV K VP+DK 
Subjt:  GGRSITVLNVAEKPSVAKSVATILSR-NQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDKL

Query:  DIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLK
        DIKRTLE+E+R+ QWLVLWLDCDREGENIA+EV+++C   N  LNI RA FSALI+R+IH+AVQ+L +PNK FADAVDARQEIDLRIGASFTRFQT+LLK
Subjt:  DIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLK

Query:  DAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKYP
        DAF +D   DDRNI+LSYGPCQFPTLGF+VER+WEIQ+HEPEEFWTINCSH SD+G ++F W RG+LFDY+ AVV YEMCV+E  ATV NVR QE LKYP
Subjt:  DAFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKYP

Query:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHPT
        P+PL+TIEL+KRASRYFRMSSEHTMKVAE+LYQAGFISYPRTETD FS  TDLH IV EQ  H  WG YAQRLLDPE+RLWRNPS GGHDDKAHPPIHPT
Subjt:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHPT

Query:  KFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPL
        KFSAGE  W+ +H +LYELVVRHFLAC SQPAVGA TTVEIDIAGE F+ SGR++LA+NYLDVYRF+SWGG+ +PTY+ GQQFVPTTLTLDSG+TRPPPL
Subjt:  KFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPL

Query:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTCF
        L+EADLL CMDK GIGTDATMHDHIKKLLDR YATKDANTRF+PTNLGEALVMGYD+MGY LWKP LR++ME +MK+VS GTK K EVL +CLQQMK CF
Subjt:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTCF

Query:  LDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ
        LDAR NK KL +AM  FF RS+    +   ++ E V+ C  C +S+M LK+   G +MVGC  FPQ
Subjt:  LDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ

O70157 DNA topoisomerase 3-alpha

6.1e-171

47.05

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Query:  VLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDKLDIKRTLE
        VL VAEK   AK +A +LS N  +R ++G S++NKI+EF+Y + GQ+  MI+TSV+GHL+   F+ ++RKW SC+P+ LF A + K+ PE+ +DIK+TLE
Subjt:  VLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDKLDIKRTLE

Query:  QESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLKDAFNIDS
        +E+   Q LV+W DCDREGENI FE++ VC AV  +L + RA FS +    +  A +NL +P++  +DAVD RQE+DLRIGA+FTRFQTL L+  F    
Subjt:  QESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLKDAFNIDS

Query:  VTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKYPPHPLNTI
        V  ++  ++SYG CQFPTLGFVVER+  IQ+  PE F  I  +H+  DG   F+W R  LF++T  +V Y++C+++  ATVV VR +   K+ P  L+T+
Subjt:  VTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKYPPHPLNTI

Query:  ELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHPTKFSAGER
        ELEK ASR  R++++ TM++AE LY  G+ISYPRTET+ F +  +L  +V +Q     WGA+AQ +L+   R    P  G   D+AHPPIHPTK+++G +
Subjt:  ELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHPTKFSAGER

Query:  GWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLL
        G   D  RLYE +VRHFLAC SQ A G  TTVEIDIA E F   G +ILARNYLDVY ++ W    +P Y  G  F P+T+ +  G T PP LL+EADL+
Subjt:  GWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLL

Query:  SCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTCFLDARVNK
        + M+K GIGTDAT  +HI+ +  R Y    ++ RF P +LG  LV GYD MGY + KP+LRA +E ++K + EG K K +VL   +Q+ K  F++A    
Subjt:  SCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTCFLDARVNK

Query:  QKLLEAMEVFF-ERSNGSGGDE-NRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ
        +KL EA+  +  ER+  +  +E   A+ E V+ C  C + DMVLK  + G + + C+ FP+
Subjt:  QKLLEAMEVFF-ERSNGSGGDE-NRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ

Q13472 DNA topoisomerase 3-alpha

1.6e-171

47.05

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Query:  VLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDKLDIKRTLE
        VL VAEK   AK +A +LS N  +R R+G S++NKI+EF+Y + GQ+  M++TSV+GHL+   F+ ++RKW SC+P+ LF A + K+ PE+ +DIK+TLE
Subjt:  VLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDKLDIKRTLE

Query:  QESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLKDAFNIDS
        +E+R+ Q LV+W DCDREGENI FE++ VC AV  +L + RA FS +    +  A +NL +P++  +DAVD RQE+DLRIGA+FTRFQTL L+  F    
Subjt:  QESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLKDAFNIDS

Query:  VTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKYPPHPLNTI
        V  ++  ++SYG CQFPTLGFVVER+  IQ+  PE F  I  +H+  DGI  F+W R  LF++T  +V Y++CV++  ATVV VR +   K+ P  L+T+
Subjt:  VTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKYPPHPLNTI

Query:  ELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHPTKFSAGER
        ELEK ASR  R++++ TM++AE LY  G+ISYPRTET+ F +  +L  +V +Q     WGA+AQ +L+   R    P  G   D+AHPPIHPTK++   +
Subjt:  ELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHPTKFSAGER

Query:  GWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLL
        G   D  RLYE +VRHFLAC SQ A G  TTVEIDIA E F   G MILARNYLDVY ++ W    +P Y  G  F P+T+ +  G T PP LL+EADL+
Subjt:  GWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLL

Query:  SCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTCFLDARVNK
        + M+K GIGTDAT  +HI+ +  R Y     + RF P +LG  LV GYD MGY + KP+LRA +E ++K + +G K K  VL   +Q+ K  F++A    
Subjt:  SCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTCFLDARVNK

Query:  QKLLEAMEVFFERSNGSGGDEN--RAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ
        +KL EA+  +F         E+   A+ E ++ C  C + DMVLK  ++G + + C+ FP+
Subjt:  QKLLEAMEVFFERSNGSGGDEN--RAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ

Q8T2T7 DNA topoisomerase 3

1.4e-164

47.21

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Query:  VLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRG-QSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDKLDIKRTL
        +LNVAEKPS AK +A ILS N+   VR+G S+YNK+++F Y I     C M  TSVTGHLME+   E+++ W SCDP+QLF AP+ K VP DK  +K+TL
Subjt:  VLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRG-QSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDKLDIKRTL

Query:  EQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLKDAFNID
        E+E ++A  L+LWLDCDREGENIAFEV+EVC          RAHFSA+I R+I  A +NL +PN+  + AVD R EIDLRIGA+FTRFQTL LK  F I 
Subjt:  EQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLKDAFNID

Query:  SVTDDR---------NI------------VLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGIS------TFSWTRGNLFDYTCAVVFYEM
        S +D++         NI            ++SYGPCQFPTLGFVVERY+ I + +PE+FW ++  H   D  S      TFSW R  LFDYT A + YE 
Subjt:  SVTDDR---------NI------------VLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGIS------TFSWTRGNLFDYTCAVVFYEM

Query:  CVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESR
        C+  + ATVV+V  +E+ +Y P PL TIEL+K AS+  R+SS  TM+ AE+LY  G ISYPRTETD F   TDL G++  Q  +  WGAYA RL++    
Subjt:  CVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESR

Query:  LWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVS
        ++  P  G ++D +HPPIHPT  + G  G   +  ++Y+ + R FLAC S+ +V A TTV IDI GE FS +G M+L   YL+VY F+      IPTY  
Subjt:  LWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVS

Query:  GQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVS
        G++F P  + L  G T  P  ++EA+LL+ MD   IGTDATM  HI+ + DRFY  K+ + +F P+NLG +LV  Y+ MG+   KPNLRA +E ++  +S
Subjt:  GQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVS

Query:  EGTKRKDEVLASCLQQMKTCFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLC
         G K K EVL S +++ K  +  A  N      +   ++E ++  GG E R +      CG C
Subjt:  EGTKRKDEVLASCLQQMKTCFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLC

Q9LVP1 DNA topoisomerase 3-alpha

8.7e-311

75.68

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Query:  GGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDKLD
        GG  +TVLNVAEKPSVAKSVA ILSR    R R+GRSRYNKIFEF+YAI GQ C M++TSV GHLMEL F +RYRKWHSCDP  L+ APV K VPEDK D
Subjt:  GGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDKLD

Query:  IKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLKD
        IK+TLE+E+R++ WLVLWLDCDREGENIAFEVV+VC AV H+L I+RAHFSALI+RDIH+AVQNL  PN+ FA+AVDARQEIDLRIGASFTRFQT+LL+D
Subjt:  IKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLKD

Query:  AFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNV-RRQETLKYP
         F IDS  ++R+ V+SYGPCQFPTLGF+VERYWEIQ+HEPEEFWTINCSH S++G++TF+W RG+LFDY  AV+ YEMCV+E TATV+NV   +E  KYP
Subjt:  AFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNV-RRQETLKYP

Query:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHPT
        P+PLNTIELEKRASRYFR+SSEHTMKVAE+LYQAGFISYPRTETD FS RTDL  +V EQ  H  WG+YAQRLL+PE  LWRNP+ GGHDDKAHPPIHPT
Subjt:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHPT

Query:  KFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPL
        KFS+GE  WS+DH  +YELVVRH+LACVSQPAV A TTVEIDIAGE FS SGR ILA+NYL+VYRFESWGGS IP Y  GQQF+PTTLTLD+ VTRPPPL
Subjt:  KFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPL

Query:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTCF
        L EADLLSCMDK GIGTDATMHDHIKKLLDR YATKDANTRF+PTNLGEALVMGYDDMGY LWKPNLRA+MEH+M  VS G K K EVL +CLQQMK CF
Subjt:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTCF

Query:  LDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ
        LDARV K KLLEAM +FFERSN +   E++  GEVV+ C LC +SDM L++NRDGN+MVGC+ +PQ
Subjt:  LDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ

Arabidopsis top hits

e value

%identity

Alignment

AT2G32000.1 DNA topoisomerase, type IA, core

3.6e-110

36.88

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Query:  ITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDKLDIKRT
        + VL VAEKPS+A S+A++LS  Q +  R G +   ++ EF+   RG   +  VTSV GH+  + F E+Y+ W + DP  LF AP+ K     K  I R 
Subjt:  ITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDKLDIKRT

Query:  LEQESRRAQWLVLWLDCDREGENIAFEVVEVC--TAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLKDAF
        L  E+R   ++VLWLDCDREGENI FEV+E       +    + RA FS++ E+DI  A+ NLV+PN+  A AVDARQEIDL++G +F+RFQT   +  +
Subjt:  LEQESRRAQWLVLWLDCDREGENIAFEVVEVC--TAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLKDAF

Query:  -NIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKYPPH
         N+D        V+SYGPCQ PTLGF V+RY  I + +PE+FW +      D       W R  LFD   A VF ++ V+  TA V++V  ++ +K  P 
Subjt:  -NIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKYPPH

Query:  PLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHPTKF
         LNT+ L K AS       +  M +AE LY  GFISYPRTE+  +    D    +R Q  + +WG Y QRLL     + ++    G D   HPPI P + 
Subjt:  PLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHPTKF

Query:  SAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLS
        +A E     D  RLY+ V +HFL  VS       T VE+ I GE F  +G+ +  + +  +  + +     +P+++ G++     + L  G T PP  L+
Subjt:  SAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLS

Query:  EADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTCFLD
        E++L+S M+K GIGTDA++  HI  + +R Y    +  +  PT LG  L+ GY  +  +L  P++R+ +E ++  V++G      V+   +QQ +  F  
Subjt:  EADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTCFLD

Query:  ARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLC
              + +E M+  FE       D  RA+ +    CG C
Subjt:  ARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLC

AT2G32000.2 DNA topoisomerase, type IA, core

8.3e-99

36.3

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Query:  HLMELAFE---ERYRKWHSCDPVQLFHAPVHKFVPEDKLDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVC--TAVNHHLNIKRAHFSALIERDI
        HL+ + F    E+Y+ W + DP  LF AP+ K     K  I R L  E+R   ++VLWLDCDREGENI FEV+E       +    + RA FS++ E+DI
Subjt:  HLMELAFE---ERYRKWHSCDPVQLFHAPVHKFVPEDKLDIKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVC--TAVNHHLNIKRAHFSALIERDI

Query:  HDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLKDAF-NIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGIS
          A+ NLV+PN+  A AVDARQEIDL++G +F+RFQT   +  + N+D        V+SYGPCQ PTLGF V+RY  I + +PE+FW +      D    
Subjt:  HDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLKDAF-NIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGIS

Query:  TFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVR
           W R  LFD   A VF ++ V+  TA V++V  ++ +K  P  LNT+ L K AS       +  M +AE LY  GFISYPRTE+  +    D    +R
Subjt:  TFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVR

Query:  EQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILAR
         Q  + +WG Y QRLL     + ++    G D   HPPI P + +A E     D  RLY+ V +HFL  VS       T VE+ I GE F  +G+ +  +
Subjt:  EQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILAR

Query:  NYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDM
         +  +  + +     +P+++ G++     + L  G T PP  L+E++L+S M+K GIGTDA++  HI  + +R Y    +  +  PT LG  L+ GY  +
Subjt:  NYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDM

Query:  GYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTCFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLC
          +L  P++R+ +E ++  V++G      V+   +QQ +  F        + +E M+  FE       D  RA+ +    CG C
Subjt:  GYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTCFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLC

AT4G31210.1 DNA topoisomerase, type IA, core

2.2e-19

24.47

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Query:  AQWLVLWLDCDREGENIAFEVVEVCT---AVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLKDAFNIDSVT
        A+ L+L  D DREGE IA+ ++E+     A++  + + R  F  + E  I  A+Q+  + +     A  AR+ +D  IG + +    LL +      S  
Subjt:  AQWLVLWLDCDREGENIAFEVVEVCT---AVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLKDAFNIDSVT

Query:  DDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNL---------FDYTCAVVFYEMCVQESTATVVNVRRQETLKYP
                 G  Q   L  V +R  EI   +P+E+WT+       D  +TFS    +L                   E  ++     V   +   T K P
Subjt:  DDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNL---------FDYTCAVVFYEMCVQESTATVVNVRRQETLKYP

Query:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQ---------AGFISYPRTETDCFSQRT--DLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGH
        P P  T  L++ A+     S+ HTMK+A+ LY+         AG I+Y RT+    +     D+  +V E+        Y +       R +        
Subjt:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQ---------AGFISYPRTETDCFSQRT--DLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGH

Query:  DDKAHPPIHPTKF----SAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGE--LFSTSGRMILARNYLDVY------------------R
        +  AH  I PT      S        D  +LY L+    +AC  +PA  A   ++I  A E  +F +S   +    Y  VY                  R
Subjt:  DDKAHPPIHPTKF----SAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGE--LFSTSGRMILARNYLDVY------------------R

Query:  FESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYAT
         E++   T+ +   G       + L    T+ PP  SE  L+  +++ GIG  +T     + L  R Y T
Subjt:  FESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYAT

AT5G63920.1 topoisomerase 3alpha

6.2e-312

75.68

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Query:  GGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDKLD
        GG  +TVLNVAEKPSVAKSVA ILSR    R R+GRSRYNKIFEF+YAI GQ C M++TSV GHLMEL F +RYRKWHSCDP  L+ APV K VPEDK D
Subjt:  GGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDKLD

Query:  IKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLKD
        IK+TLE+E+R++ WLVLWLDCDREGENIAFEVV+VC AV H+L I+RAHFSALI+RDIH+AVQNL  PN+ FA+AVDARQEIDLRIGASFTRFQT+LL+D
Subjt:  IKRTLEQESRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLKD

Query:  AFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNV-RRQETLKYP
         F IDS  ++R+ V+SYGPCQFPTLGF+VERYWEIQ+HEPEEFWTINCSH S++G++TF+W RG+LFDY  AV+ YEMCV+E TATV+NV   +E  KYP
Subjt:  AFNIDSVTDDRNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNV-RRQETLKYP

Query:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHPT
        P+PLNTIELEKRASRYFR+SSEHTMKVAE+LYQAGFISYPRTETD FS RTDL  +V EQ  H  WG+YAQRLL+PE  LWRNP+ GGHDDKAHPPIHPT
Subjt:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHPT

Query:  KFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPL
        KFS+GE  WS+DH  +YELVVRH+LACVSQPAV A TTVEIDIAGE FS SGR ILA+NYL+VYRFESWGGS IP Y  GQQF+PTTLTLD+ VTRPPPL
Subjt:  KFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPL

Query:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTCF
        L EADLLSCMDK GIGTDATMHDHIKKLLDR YATKDANTRF+PTNLGEALVMGYDDMGY LWKPNLRA+MEH+M  VS G K K EVL +CLQQMK CF
Subjt:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTCF

Query:  LDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ
        LDARV K KLLEAM +FFERSN +   E++  GEVV+ C LC +SDM L++NRDGN+MVGC+ +PQ
Subjt:  LDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMVGCLAFPQ

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGTCCGGCGGCCGTTCGATTACCGTCCTCAATGTGGCAGAGAAGCCATCGGTGGCAAAATCTGTCGCTACCATACTCTCCAGGAACCAGGGTCTACGAGTTCGCGATGG
TCGCTCTCGCTACAACAAGATTTTCGAGTTCAACTACGCCATTCGAGGCCAGTCTTGTAATATGATCGTCACTTCTGTCACTGGCCACCTCATGGAGCTTGCTTTCGAAG
AACGGTACCGCAAATGGCATTCCTGCGACCCAGTCCAGCTCTTCCACGCTCCCGTCCACAAATTTGTCCCCGAGGACAAGTTGGATATAAAGAGGACTTTGGAACAAGAA
TCTAGAAGGGCTCAATGGCTTGTCCTTTGGCTTGATTGTGATAGAGAAGGAGAGAATATTGCATTCGAAGTGGTGGAAGTTTGCACAGCAGTAAATCATCATCTTAACAT
TAAGAGAGCTCACTTCTCTGCTTTGATTGAAAGGGATATTCACGATGCTGTTCAAAATCTTGTCCAACCAAATAAATGGTTTGCTGATGCAGTTGATGCTAGACAAGAAA
TTGATCTAAGAATTGGAGCTTCTTTCACTAGGTTCCAAACTCTGCTGTTGAAAGATGCATTTAATATTGATTCTGTCACAGATGACAGAAATATTGTTTTGAGTTATGGG
CCATGTCAGTTTCCTACTCTTGGCTTTGTTGTTGAGCGGTACTGGGAGATTCAATCCCATGAGCCAGAAGAATTTTGGACAATCAACTGTTCACACAATTCTGATGATGG
GATTTCTACGTTTAGTTGGACAAGAGGGAATCTATTTGATTATACCTGTGCTGTTGTATTCTATGAAATGTGTGTACAAGAATCCACTGCTACAGTTGTAAATGTTAGAC
GACAAGAGACATTAAAGTACCCTCCTCATCCATTGAATACAATTGAGCTTGAAAAACGAGCTTCACGGTACTTCCGAATGAGTTCTGAACACACCATGAAGGTGGCCGAA
GATCTATACCAAGCAGGTTTCATTAGTTATCCTCGTACAGAGACTGATTGCTTTTCTCAAAGGACTGATCTTCATGGTATTGTGCGAGAACAACAAGAACACCAAATATG
GGGAGCATATGCACAGAGGTTGCTAGATCCGGAATCAAGACTTTGGAGGAATCCTAGTGGTGGGGGGCATGATGACAAAGCTCATCCACCTATTCACCCAACAAAGTTCT
CGGCTGGGGAACGTGGATGGAGCCAGGATCACCATAGATTATATGAGCTAGTCGTTCGTCATTTCCTTGCATGTGTATCACAGCCAGCTGTAGGTGCTGTAACTACGGTT
GAAATTGATATTGCTGGTGAATTGTTTTCTACGTCTGGGAGGATGATACTAGCAAGAAATTACCTGGATGTTTACCGCTTTGAATCATGGGGAGGTTCAACTATTCCAAC
CTACGTTTCTGGGCAACAGTTTGTTCCAACAACATTAACCCTTGATTCGGGTGTCACTAGACCACCTCCCCTTCTGAGTGAAGCTGATTTGCTTTCTTGTATGGATAAGG
AGGGAATTGGTACAGATGCAACAATGCATGACCATATCAAGAAGCTGTTGGATAGATTTTATGCAACGAAGGATGCAAACACTCGGTTCACACCAACTAACCTTGGTGAG
GCTCTGGTTATGGGATATGACGACATGGGGTATAATCTGTGGAAGCCAAACCTTAGAGCAATCATGGAGCATGAGATGAAAGCAGTTAGTGAGGGCACTAAGCGAAAAGA
TGAAGTGTTGGCTTCATGCTTGCAGCAGATGAAAACTTGCTTCTTAGATGCAAGGGTCAATAAGCAAAAACTTCTTGAAGCAATGGAGGTTTTCTTTGAGAGATCTAATG
GTTCTGGCGGGGATGAAAATCGTGCAGTTGGAGAAGTTGTTCAGCTGTGTGGGCTGTGTCAGGACTCAGATATGGTGCTTAAAAGAAACAGGGATGGAAATTACATGGTT
GGATGTTTGGCCTTTCCCCAGGTGTGA

mRNA sequence

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Protein sequence

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MSGGRSITVLNVAEKPSVAKSVATILSRNQGLRVRDGRSRYNKIFEFNYAIRGQSCNMIVTSVTGHLMELAFEERYRKWHSCDPVQLFHAPVHKFVPEDKLDIKRTLEQE
SRRAQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHDAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTLLLKDAFNIDSVTDDRNIVLSYG
PCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFSWTRGNLFDYTCAVVFYEMCVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAE
DLYQAGFISYPRTETDCFSQRTDLHGIVREQQEHQIWGAYAQRLLDPESRLWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHRLYELVVRHFLACVSQPAVGAVTTV
EIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVSGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGE
ALVMGYDDMGYNLWKPNLRAIMEHEMKAVSEGTKRKDEVLASCLQQMKTCFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQLCGLCQDSDMVLKRNRDGNYMV
GCLAFPQV

CSPI03G37060 (gene) of Cucumber (PI 183967) v1 genome