CuGenDBv2

Gene ID	CSPI03G38290
Organism	Cucumis sativus L. var. sativus cv. PI 183967 (Cucumber (PI 183967) v1)
Description	Ribonucleoside-diphosphate reductase
Genome location	Chr3:33135133..33135737
RNA-Seq Expression	CSPI03G38290
Synteny	CSPI03G38290
Gene Ontology terms	GO:0006260 - DNA replication (biological process) GO:0009263 - deoxyribonucleotide biosynthetic process (biological process) GO:0005971 - ribonucleoside-diphosphate reductase complex (cellular component) GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (molecular function) GO:0005524 - ATP binding (molecular function)
InterPro domains	IPR000788 - Ribonucleotide reductase large subunit, C-terminal IPR039718 - Ribonucleoside-diphosphate reductase large subunit

Homology

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GenBank top hits

e value

%identity

Alignment

KAG7033727.1 Ribonucleoside-diphosphate reductase large subunit [Cucurbita argyrosperma subsp. argyrosperma]

5.7e-24

63.46

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Query:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH
        SKLIG RDSKN                   ++ IDVNYYPV+TA   NLRHRPIG+GVQ LADTFILLGM FDSPEAQ+LNKDIFEAIYYHAL +   + 
Subjt:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH

Query:  AVEG
        AVEG
Subjt:  AVEG

TYK12445.1 ribonucleoside-diphosphate reductase large subunit-like isoform X3 [Cucumis melo var. makuwa]

4.3e-24

63.46

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Query:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH
        SKL+G RDSKN                   ++ IDVNYYPV+TA   NLRHRPIG+GVQ LADTFILLGM FDSPEAQ+LNKDIFEAIYYHAL +   L 
Subjt:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH

Query:  AVEG
        AVEG
Subjt:  AVEG

XP_004141975.1 ribonucleoside-diphosphate reductase large subunit [Cucumis sativus]

4.3e-24

63.46

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Query:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH
        SKL+G RDSKN                   ++ IDVNYYPV+TA   NLRHRPIG+GVQ LADTFILLGM FDSPEAQ+LNKDIFEAIYYHAL +   L 
Subjt:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH

Query:  AVEG
        AVEG
Subjt:  AVEG

XP_008440987.1 PREDICTED: ribonucleoside-diphosphate reductase large subunit [Cucumis melo]

4.3e-24

63.46

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Query:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH
        SKL+G RDSKN                   ++ IDVNYYPV+TA   NLRHRPIG+GVQ LADTFILLGM FDSPEAQ+LNKDIFEAIYYHAL +   L 
Subjt:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH

Query:  AVEG
        AVEG
Subjt:  AVEG

XP_022949664.1 ribonucleoside-diphosphate reductase large subunit-like [Cucurbita moschata]

5.7e-24

63.46

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Query:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH
        SKLIG RDSKN                   ++ IDVNYYPV+TA   NLRHRPIG+GVQ LADTFILLGM FDSPEAQ+LNKDIFEAIYYHAL +   + 
Subjt:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH

Query:  AVEG
        AVEG
Subjt:  AVEG

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KJ45 Ribonucleoside-diphosphate reductase

2.1e-24

63.46

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Query:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH
        SKL+G RDSKN                   ++ IDVNYYPV+TA   NLRHRPIG+GVQ LADTFILLGM FDSPEAQ+LNKDIFEAIYYHAL +   L 
Subjt:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH

Query:  AVEG
        AVEG
Subjt:  AVEG

A0A1S3B2F2 Ribonucleoside-diphosphate reductase

2.1e-24

63.46

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Query:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH
        SKL+G RDSKN                   ++ IDVNYYPV+TA   NLRHRPIG+GVQ LADTFILLGM FDSPEAQ+LNKDIFEAIYYHAL +   L 
Subjt:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH

Query:  AVEG
        AVEG
Subjt:  AVEG

A0A5A7SMV6 Ribonucleoside-diphosphate reductase

2.1e-24

63.46

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Query:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH
        SKL+G RDSKN                   ++ IDVNYYPV+TA   NLRHRPIG+GVQ LADTFILLGM FDSPEAQ+LNKDIFEAIYYHAL +   L 
Subjt:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH

Query:  AVEG
        AVEG
Subjt:  AVEG

A0A5D3CLK7 Ribonucleoside-diphosphate reductase

2.1e-24

63.46

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Query:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH
        SKL+G RDSKN                   ++ IDVNYYPV+TA   NLRHRPIG+GVQ LADTFILLGM FDSPEAQ+LNKDIFEAIYYHAL +   L 
Subjt:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH

Query:  AVEG
        AVEG
Subjt:  AVEG

A0A6J1GDH5 Ribonucleoside-diphosphate reductase

2.7e-24

63.46

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Query:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH
        SKLIG RDSKN                   ++ IDVNYYPV+TA   NLRHRPIG+GVQ LADTFILLGM FDSPEAQ+LNKDIFEAIYYHAL +   + 
Subjt:  SKLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVSL--LH

Query:  AVEG
        AVEG
Subjt:  AVEG

SwissProt top hits

e value

%identity

Alignment

P07742 Ribonucleoside-diphosphate reductase large subunit

9.1e-17

66.67

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Query:  IDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHAL
        ID+NYYP+  A++ N RHRPIG+GVQ LAD FIL+   F+SPEAQ LNK IFE IYY AL
Subjt:  IDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHAL

P12848 Ribonucleoside-diphosphate reductase large subunit

9.1e-17

68.33

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Query:  IDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHAL
        ID+NYYP+  A + N RHRPIG+GVQ LAD FILL   FDS EAQ+LNK IFE IYY AL
Subjt:  IDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHAL

P20503 Ribonucleoside-diphosphate reductase large subunit

9.1e-17

68.33

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Query:  IDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHAL
        ID+NYYP+  A + N RHRPIG+GVQ LAD FILL   FDS EAQ+LNK IFE IYY AL
Subjt:  IDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHAL

Q76RD8 Ribonucleoside-diphosphate reductase large subunit

9.1e-17

68.33

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Query:  IDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHAL
        ID+NYYP+  A + N RHRPIG+GVQ LAD FILL   FDS EAQ+LNK IFE IYY AL
Subjt:  IDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHAL

Q9SJ20 Ribonucleoside-diphosphate reductase large subunit

6.5e-23

60.87

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Query:  KLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHAL
        KL G  DSKN                   ++ IDVNYYPV+TA   N+RHRPIG+GVQ LAD FILLGM FDSPEAQ+LNKDIFE IYYHAL
Subjt:  KLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHAL

Arabidopsis top hits

e value

%identity

Alignment

AT2G21790.1 ribonucleotide reductase 1

4.6e-24

60.87

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Query:  KLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHAL
        KL G  DSKN                   ++ IDVNYYPV+TA   N+RHRPIG+GVQ LAD FILLGM FDSPEAQ+LNKDIFE IYYHAL
Subjt:  KLIGGRDSKN-------------------HEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHAL

Sequences

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CDS sequence

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ATGATATTAAATTTTCATCCATCCAGGAGGTTAAAGCTTTTAGATCAATATGCAATTTTAAGATCTATTACCTTACTGCAGGGTTCCAACCAAGTCTCAGCATCTAAGCT
TATTGGTGGCAGAGATTCCAAGAATCATGAGAAAATTGATGTCAACTATTACCCTGTTGATACTGCCAACATGTGTAATCTAAGACATAGACCCATTGGTGTTGGGGTGC
AAGATCTTGCAGATACTTTCATTTTACTGGGGATGTTCTTTGATTCACCTGAGGCCCAAGAACTGAACAAGGATATATTTGAGGCCATATATTACCATGCTCTTGTGAGC
TTGCTGCATGCTGTGGAAGGCCGGCCCCTATGA

mRNA sequence

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Protein sequence

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MILNFHPSRRLKLLDQYAILRSITLLQGSNQVSASKLIGGRDSKNHEKIDVNYYPVDTANMCNLRHRPIGVGVQDLADTFILLGMFFDSPEAQELNKDIFEAIYYHALVS
LLHAVEGRPL

CSPI03G38290 (gene) of Cucumber (PI 183967) v1 genome