CuGenDBv2

Gene ID	CSPI04G17570
Organism	Cucumis sativus L. var. sativus cv. PI 183967 (Cucumber (PI 183967) v1)
Description	DNA topoisomerase 2-binding protein 1 isoform X2
Genome location	Chr4:15050158..15050950
RNA-Seq Expression	CSPI04G17570
Synteny	CSPI04G17570
Gene Ontology terms	GO:0016853 - isomerase activity (molecular function)
InterPro domains	IPR001357 - BRCT domain IPR036420 - BRCT domain superfamily

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0052213.1 DNA topoisomerase 2-binding protein 1 isoform X2 [Cucumis melo var. makuwa]

7.3e-72

89.81

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Query:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH
        M+KIVNMILRGGGSRYM+FNDKLTHIIVG+ SEMEKKEVRDIA SGVVHVVR+NWLEDCDRQKKEIPILGRHMAYDE+IPKASSKMSTIV+D++KVPNVH
Subjt:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH

Query:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS
        PIVPS V EGNIHVS GKTS+ VERIEEKSETKVNGDRKMKLSQKSQQCV NGTNKS
Subjt:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS

TYK01780.1 DNA topoisomerase 2-binding protein 1 isoform X2 [Cucumis melo var. makuwa]

7.3e-72

89.81

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Query:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH
        M+KIVNMILRGGGSRYM+FNDKLTHIIVG+ SEMEKKEVRDIA SGVVHVVR+NWLEDCDRQKKEIPILGRHMAYDE+IPKASSKMSTIV+D++KVPNVH
Subjt:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH

Query:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS
        PIVPS V EGNIHVS GKTS+ VERIEEKSETKVNGDRKMKLSQKSQQCV NGTNKS
Subjt:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS

XP_031739847.1 uncharacterized protein LOC116403316 [Cucumis sativus]

4.7e-79

98.09

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Query:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH
        M+KIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLE+CDRQKKEIPILGRHMAYDE+IPKASSKMSTIVMDQNKVPNVH
Subjt:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH

Query:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS
        PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS
Subjt:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS

XP_031740436.1 LOW QUALITY PROTEIN: DNA topoisomerase 2-binding protein 1 [Cucumis sativus]

4.7e-79

98.09

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Query:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH
        M+KIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLE+CDRQKKEIPILGRHMAYDE+IPKASSKMSTIVMDQNKVPNVH
Subjt:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH

Query:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS
        PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS
Subjt:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS

XP_031745859.1 LOW QUALITY PROTEIN: DNA topoisomerase 2-binding protein 1-A [Cucumis sativus]

4.7e-79

98.09

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Query:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH
        M+KIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLE+CDRQKKEIPILGRHMAYDE+IPKASSKMSTIVMDQNKVPNVH
Subjt:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH

Query:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS
        PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS
Subjt:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS

TrEMBL top hits

e value

%identity

Alignment

A0A1S3BAL1 DNA topoisomerase 2-binding protein 1 isoform X3

3.5e-72

89.81

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Query:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH
        M+KIVNMILRGGGSRYM+FNDKLTHIIVG+ SEMEKKEVRDIA SGVVHVVR+NWLEDCDRQKKEIPILGRHMAYDE+IPKASSKMSTIV+D++KVPNVH
Subjt:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH

Query:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS
        PIVPS V EGNIHVS GKTS+ VERIEEKSETKVNGDRKMKLSQKSQQCV NGTNKS
Subjt:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS

A0A1S4DV57 DNA topoisomerase 2-binding protein 1 isoform X1

3.5e-72

89.81

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Query:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH
        M+KIVNMILRGGGSRYM+FNDKLTHIIVG+ SEMEKKEVRDIA SGVVHVVR+NWLEDCDRQKKEIPILGRHMAYDE+IPKASSKMSTIV+D++KVPNVH
Subjt:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH

Query:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS
        PIVPS V EGNIHVS GKTS+ VERIEEKSETKVNGDRKMKLSQKSQQCV NGTNKS
Subjt:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS

A0A1S4DV59 DNA topoisomerase 2-binding protein 1 isoform X2

3.5e-72

89.81

Show/hide

Query:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH
        M+KIVNMILRGGGSRYM+FNDKLTHIIVG+ SEMEKKEVRDIA SGVVHVVR+NWLEDCDRQKKEIPILGRHMAYDE+IPKASSKMSTIV+D++KVPNVH
Subjt:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH

Query:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS
        PIVPS V EGNIHVS GKTS+ VERIEEKSETKVNGDRKMKLSQKSQQCV NGTNKS
Subjt:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS

A0A5A7U8G5 DNA topoisomerase 2-binding protein 1 isoform X2

3.5e-72

89.81

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Query:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH
        M+KIVNMILRGGGSRYM+FNDKLTHIIVG+ SEMEKKEVRDIA SGVVHVVR+NWLEDCDRQKKEIPILGRHMAYDE+IPKASSKMSTIV+D++KVPNVH
Subjt:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH

Query:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS
        PIVPS V EGNIHVS GKTS+ VERIEEKSETKVNGDRKMKLSQKSQQCV NGTNKS
Subjt:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS

A0A5D3BRP8 DNA topoisomerase 2-binding protein 1 isoform X2

3.5e-72

89.81

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Query:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH
        M+KIVNMILRGGGSRYM+FNDKLTHIIVG+ SEMEKKEVRDIA SGVVHVVR+NWLEDCDRQKKEIPILGRHMAYDE+IPKASSKMSTIV+D++KVPNVH
Subjt:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVH

Query:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS
        PIVPS V EGNIHVS GKTS+ VERIEEKSETKVNGDRKMKLSQKSQQCV NGTNKS
Subjt:  PIVPSNVSEGNIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS

SwissProt top hits	e value	%identity	Alignment
No hits found

Arabidopsis top hits

e value

%identity

Alignment

AT1G77320.1 transcription coactivators

9.6e-22

40.69

Show/hide

Query:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKAS--------SKMSTIVMD
        M+K+  ++ RGGGSRYM+ N+++THI+VG  SE EK+E R +A SGV+ VV  +WLEDCDR+KKEIP+   + A   I+P+ S        ++MS+  M+
Subjt:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKAS--------SKMSTIVMD

Query:  QNKVPNVHPIVPSNVSEGNIHVS------IGKTSIAVERIEEKSE
        Q K  +   +V  + S  +I+VS      +GK   A++    K E
Subjt:  QNKVPNVHPIVPSNVSEGNIHVS------IGKTSIAVERIEEKSE

AT1G77320.2 transcription coactivators

9.6e-22

40.69

Show/hide

Query:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKAS--------SKMSTIVMD
        M+K+  ++ RGGGSRYM+ N+++THI+VG  SE EK+E R +A SGV+ VV  +WLEDCDR+KKEIP+   + A   I+P+ S        ++MS+  M+
Subjt:  MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKAS--------SKMSTIVMD

Query:  QNKVPNVHPIVPSNVSEGNIHVS------IGKTSIAVERIEEKSE
        Q K  +   +V  + S  +I+VS      +GK   A++    K E
Subjt:  QNKVPNVHPIVPSNVSEGNIHVS------IGKTSIAVERIEEKSE

Sequences

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CDS sequence

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ATGCAGAAGATTGTAAATATGATTCTCAGAGGTGGAGGCTCCCGATACATGGTTTTCAATGACAAATTAACACACATAATAGTTGGAGATTCGTCAGAAATGGAGAAAAA
GGAGGTTAGAGATATTGCTACTTCAGGAGTTGTTCATGTGGTTAGATCCAACTGGCTTGAAGATTGTGATCGTCAGAAGAAGGAGATCCCTATTCTTGGTAGACACATGG
CATATGATGAAATTATTCCTAAAGCATCTAGTAAAATGAGCACCATTGTTATGGATCAAAATAAAGTTCCAAATGTTCATCCAATCGTGCCATCAAATGTGTCAGAAGGA
AATATTCATGTTAGCATTGGAAAGACGTCAATAGCAGTGGAAAGAATTGAAGAAAAAAGTGAAACAAAAGTGAATGGAGACAGGAAAATGAAATTATCCCAGAAAAGCCA
ACAATGTGTAGCAAATGGTACAAACAAGAGTTGA

mRNA sequence

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Protein sequence

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MQKIVNMILRGGGSRYMVFNDKLTHIIVGDSSEMEKKEVRDIATSGVVHVVRSNWLEDCDRQKKEIPILGRHMAYDEIIPKASSKMSTIVMDQNKVPNVHPIVPSNVSEG
NIHVSIGKTSIAVERIEEKSETKVNGDRKMKLSQKSQQCVANGTNKS

CSPI04G17570 (gene) of Cucumber (PI 183967) v1 genome