CuGenDBv2

Gene ID	CaUC05G087480
Organism	Citrullus amarus (Watermelon (USVL246-FR2) v1)
Description	DNA topoisomerase
Genome location	Ciama_Chr05:7661498..7687128
RNA-Seq Expression	CaUC05G087480
Synteny	CaUC05G087480
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0005634 - nucleus (cellular component) GO:0003677 - DNA binding (molecular function) GO:0003917 - DNA topoisomerase type I activity (molecular function)
InterPro domains	IPR000380 - DNA topoisomerase, type IA IPR003601 - DNA topoisomerase, type IA, domain 2 IPR003602 - DNA topoisomerase, type IA, DNA-binding domain IPR006171 - TOPRIM domain IPR013497 - DNA topoisomerase, type IA, central IPR013824 - DNA topoisomerase, type IA, central region, subdomain 1 IPR013825 - DNA topoisomerase, type IA, central region, subdomain 2 IPR013826 - DNA topoisomerase, type IA, central region, subdomain 3 IPR023405 - DNA topoisomerase, type IA, core domain IPR023406 - DNA topoisomerase, type IA, active site IPR034144 - DNA topoisomerase 3-like, TOPRIM domain

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAG6582102.1 DNA topoisomerase 3-beta, partial [Cucurbita argyrosperma subsp. sororia]

0.0e+00

95.64

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL
        MVAS+VLMVAEKPSIALSIASALSHGQMSTRKGST+VHEFDGRFLGHHAHYKVTSVIGHVFSIDFPA FQDWK TDPLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNE RKKVYRARFSSVTEKDILKALDNLV+PNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERG+LFD DV  MFQKRVMEDGIAEVT+ISEKQE+KVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW
        LKVASSALG+GPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPM LATEDM+GRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKY+RTKIQFSIAGEIFNCTGS VMVKGFTSIMPWLAVNEKKLPQFLKG+KIEVA+V+LYQGNT+PPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQIT VAKGQADH SVVQNVLQQFKQKYSYFVKKIDHMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA
        EAQFSPLA+SGRALSKCGKCLRYMKFISSQPQRLYC TCEEVYYLPQ+GAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGI+TLYGA
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP
        AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPV APNWKLNCNKCNCLVFLPQGAHRI+TTNEKCA+CDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP

Query:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF
        LE GATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGR     GRGRGR+SGKLMDPKMSFRDF
Subjt:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF

XP_022955609.1 DNA topoisomerase 3-beta isoform X1 [Cucurbita moschata]

0.0e+00

95.52

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL
        MVAS+VLMVAEKPSIALSIASALSHGQMSTRKGST+VHEFDGRFLGHHAHYKVTSVIGHVFSIDFPA FQDWK TDPLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNE RKKVYRARFSSVTEKDILKALDNLV+PNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERG+LFD DV  MFQKRVMEDGIAEVT+ISEKQE+KVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW
        LKVASSALG+GPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVR+LLSDGYSKPRSGTDVGDHPPITPM LATEDM+GRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKY+RTKIQFSIAGEIFNCTGS VMVKGFTSIMPWLAVNEKKLPQFLKG+KIEVA+V+LYQGNT+PPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQIT VAKGQADH SVVQNVLQQFKQKYSYFVKKIDHMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA
        EAQFSPLA+SGRALSKCGKCLRYMKFISSQPQRLYC TCEEVYYLPQ+GAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGI+TLYGA
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP
        AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPV APNWKLNCNKCNCLVFLPQGAHRI+TTNEKCA+CDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP

Query:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF
        LE GATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGR     GRGRGR+SGKLMDPKMSFRDF
Subjt:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF

XP_022979706.1 DNA topoisomerase 3-beta isoform X1 [Cucurbita maxima]

0.0e+00

95.52

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL
        MVAS+VLMVAEKPSIALSIASALSHGQMSTRKGST+VHEFDGRFLGHHAHYKVTSVIGHVFSIDFPA FQDWK TDPLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNE RKKVYRARFSSVTEKDILKALDNLV+PNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERG+LFD DV  MFQKRVMEDGIAEVT+ISEKQE+KVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW
        LKVASSALG+GPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPM LATEDM+GRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGS V+VKGFTSIMPWLAVNEKKLPQFLKG+KIEVA+V+LYQGNT+PPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQIT VAKGQADH SVVQNVLQQFKQKYSYFVKKIDHMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA
        EAQFSPLA+SGRALSKCGKCLRYMKFISSQPQRLYC TCEEVYYLPQ+GAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGI+ LYGA
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP
        AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPV APNWKLNCNKCNCLVFLPQGAHRI+TTNEKCA+CDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP

Query:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF
        LE GATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGR     GRGRGR+SGKLMDPKMSFRDF
Subjt:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF

XP_023528530.1 DNA topoisomerase 3-beta isoform X1 [Cucurbita pepo subsp. pepo]

0.0e+00

95.75

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL
        MVAS+VLMVAEKPSIALSIASALSHGQMSTRKGST+VHEFDGRFLGHHAHYKVTSVIGHVFSIDFPA FQDWK TDPLDLFQASVIK ESNPKAHIRQHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGN+ RKKVYRARFSSVTEKDILKALDNLV+PNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERG+LFD DV  MFQKRVMEDGIAEVT+ISEKQE+KVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW
        LKVASSALG+GPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPM LATEDM+GRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGS VMVKGFTSIMPWLAVNEKKLPQFLKG+KIEVA+V+LYQGNT+PPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQIT VAKGQADH SVVQNVLQQFKQKYSYFVKKIDHMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA
        EAQFSPLA+SGRALSKCGKCLRYMKFISSQPQRLYC TCEEVYYLPQ+GAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGI+TLYGA
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP
        AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPV APNWKLNCNKCNCLVFLPQGAHRI+TTNEKCA+CDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP

Query:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF
        LE GATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGR   GRGRGR+SGKLMDPKMSFRDF
Subjt:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF

XP_038891105.1 DNA topoisomerase 3-beta isoform X1 [Benincasa hispida]

0.0e+00

96.67

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL
        MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWK+TDPLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPN+NEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTF PEKFWSVCPYIMQNGYELNLDWERGKLFD DVTAMFQKRV+EDGIAEVTEISEKQENKVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW
        LKVASSALGFGPQ+AMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLH+L+KN EWGDYVRMLLSDGYSKPRSGTDVGDHPPITPM LATEDMLGRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGE+FNCTGSRV+VKGFTSIMPWLAVNEKKLPQFLKGEKIEVARV+LYQGNTTPPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRL PTNLGITL+RGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKY YFVKKIDHMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA
        EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYC  CEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGI+TLYGA
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP
        AKTNPSSGASSKGMGMPCFLC HPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRIST NEKCADCDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP

Query:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF
        LE GATLFVGCILCDEFLHSLLEMKHGKS FRGRGS    RGRGRGRGRGGRGRGRNSG+ MDPKMSFRDF
Subjt:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF

TrEMBL top hits

e value

%identity

Alignment

A0A0A0L9C7 DNA topoisomerase

0.0e+00

95.52

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL
        MVA TVLMVAEKPSIALSIASALSHGQMSTRKGST+VHEFDGRFLGHHA+YKVTSVIGHVFSIDF AGFQDWK+TDPLDLFQASVIKTESNPKAHI QHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGN  RKKVYRARFSSVTEKDILKALDNLV+PNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYI+Q GYELNLDWERGKLFD DVTAMFQKRV+EDGIAEVTEISEKQENKVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW
        LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLH+LVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPM LATEDMLGRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRV VKGFTSIMPWLAVNEKKLPQFLKGEKIEVARV+LYQGNTTPPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIE QITLVAKGQADHSSVVQ+VLQQF+QKYSYFVKKIDHMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA
        EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYC  CEEVYYLPQKG IKLYKELTCPLDNFELLI+SLPGPEGKSFPLCPYCYNSPPFEGINTLYGA
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP
        +K NPSSG SSKGMGMPCF+CPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLP+GAHRISTT +KCADCDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP

Query:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF
        LEDGATLFVGCILCDEFLHSLLEMKHGKSF R RGSRGRGRGRGRGRG    GRGR+SGK MDPKMSFRDF
Subjt:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF

A0A1S3AYH7 DNA topoisomerase

0.0e+00

95.98

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL
        MVASTVLMVAEKPSIALSIASALSHGQMSTRKGST+VHEFDGRFLGHHA+YKVTSVIGH+FSIDF AGFQDWKTT+PLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGN  RKKVYRARFSSVTEKDILKALDNLV+PNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFD DVTAMFQKRV+EDGIAEVTEISEKQENKVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW
        LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLH+LVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPM  ATEDMLGRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRV VKGFTSIMPWLAVNEKKLPQFLKGEKIEVARV+LYQGNTTPPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIE QITLVAKGQADHSSVV++VLQQFKQKYSYFVKKID MDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA
        EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYC  CEEVYYLPQKG IKLYKELTCPLDNFELLI SLPGPEGKSFPLCPYCYNSPPFEGI+TLYGA
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP
        +KTNPSSG SSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTT++KCADCDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP

Query:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF
        LEDGATLFVGCILCDEFLHSLLEMKHG SF R R SRGRGRGRGRGRGRG  GRGRNSGK MDPKMSFRDF
Subjt:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF

A0A5A7VKD3 DNA topoisomerase

0.0e+00

95.98

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL
        MVASTVLMVAEKPSIALSIASALSHGQMSTRKGST+VHEFDGRFLGHHA+YKVTSVIGH+FSIDF AGFQDWKTT+PLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGN  RKKVYRARFSSVTEKDILKALDNLV+PNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFD DVTAMFQKRV+EDGIAEVTEISEKQENKVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW
        LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLH+LVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPM  ATEDMLGRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRV VKGFTSIMPWLAVNEKKLPQFLKGEKIEVARV+LYQGNTTPPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIE QITLVAKGQADHSSVV++VLQQFKQKYSYFVKKID MDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA
        EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYC  CEEVYYLPQKG IKLYKELTCPLDNFELLI SLPGPEGKSFPLCPYCYNSPPFEGI+TLYGA
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP
        +KTNPSSG SSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTT++KCADCDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP

Query:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF
        LEDGATLFVGCILCDEFLHSLLEMKHG SF R R SRGRGRGRGRGRGRG  GRGRNSGK MDPKMSFRDF
Subjt:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF

A0A6J1GWS0 DNA topoisomerase

0.0e+00

95.52

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL
        MVAS+VLMVAEKPSIALSIASALSHGQMSTRKGST+VHEFDGRFLGHHAHYKVTSVIGHVFSIDFPA FQDWK TDPLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNE RKKVYRARFSSVTEKDILKALDNLV+PNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERG+LFD DV  MFQKRVMEDGIAEVT+ISEKQE+KVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW
        LKVASSALG+GPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVR+LLSDGYSKPRSGTDVGDHPPITPM LATEDM+GRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKY+RTKIQFSIAGEIFNCTGS VMVKGFTSIMPWLAVNEKKLPQFLKG+KIEVA+V+LYQGNT+PPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQIT VAKGQADH SVVQNVLQQFKQKYSYFVKKIDHMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA
        EAQFSPLA+SGRALSKCGKCLRYMKFISSQPQRLYC TCEEVYYLPQ+GAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGI+TLYGA
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP
        AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPV APNWKLNCNKCNCLVFLPQGAHRI+TTNEKCA+CDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP

Query:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF
        LE GATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGR     GRGRGR+SGKLMDPKMSFRDF
Subjt:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF

A0A6J1IRJ0 DNA topoisomerase

0.0e+00

95.52

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL
        MVAS+VLMVAEKPSIALSIASALSHGQMSTRKGST+VHEFDGRFLGHHAHYKVTSVIGHVFSIDFPA FQDWK TDPLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNE RKKVYRARFSSVTEKDILKALDNLV+PNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERG+LFD DV  MFQKRVMEDGIAEVT+ISEKQE+KVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW
        LKVASSALG+GPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPM LATEDM+GRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGS V+VKGFTSIMPWLAVNEKKLPQFLKG+KIEVA+V+LYQGNT+PPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQIT VAKGQADH SVVQNVLQQFKQKYSYFVKKIDHMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA
        EAQFSPLA+SGRALSKCGKCLRYMKFISSQPQRLYC TCEEVYYLPQ+GAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGI+ LYGA
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP
        AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPV APNWKLNCNKCNCLVFLPQGAHRI+TTNEKCA+CDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTP

Query:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF
        LE GATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGR     GRGRGR+SGKLMDPKMSFRDF
Subjt:  LEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF

SwissProt top hits

e value

%identity

Alignment

F4ISQ7 DNA topoisomerase 3-beta

0.0e+00

76.44

Show/hide

Query:  VLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHLSREAR
        VLMVAEKPSIALSIAS LSHGQMSTR+GST+VHEFDG F G  AHY+VTSVIGHVFS+DFP  +Q+W T DP DLF A +IK ESNPKAHI +HLS EAR
Subjt:  VLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHLSREAR

Query:  GCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSR
        GC  +VLWLDCDREGENICFEVIE TGF   + ++KVYRARFSSVTEKDI KA+DNLV+PNR+EALAVDARQEIDLKVGVAF+RFQT++FQGKY NLD R
Subjt:  GCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSR

Query:  LISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNLLKVAS
        +ISYGPCQTPTLGFCVQR++ I TFKPEKFW++ PYI ++GYEL L+WER +LFD +   +FQK V+E   A+V ++SEKQE K RP+GLNTVNLLKVAS
Subjt:  LISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNLLKVAS

Query:  SALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAWRLYQY
        SALGFGPQ AM LAERLYTQGFISYPRTESTAYPSSFDF  TL + V NP WG YV+ LLSDG+  P+SGTD GDHPPITPM  ATE M+G DAWRLYQY
Subjt:  SALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAWRLYQY

Query:  VCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHGIGTDA
        VCQHF+G++S +CKYIRTK++ SI GE F+CTG RV  KGFT+IMPW AV+EKKLP FLKGE+IEV RVELY+GNT PPDYL+ESELISLMEKHGIGTDA
Subjt:  VCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHGIGTDA

Query:  SIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALFEAQFS
        SI VHINNIGERNYVQVQ+GR++VPT LGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHS VVQ+V+QQF++K+SYFV++I+HMDALFEAQFS
Subjt:  SIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALFEAQFS

Query:  PLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGAAKTNP
        PLADSGRALSKCGKCLRYMK I++ P RL+C TCEEVYYLPQKG +KLYKELTCPLDNFEL+I+S+PGPEGKSFPLCPYCYNSPPFEGI+TL+GA+KT  
Subjt:  PLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGAAKTNP

Query:  SSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTPLEDGA
        +   +  G GMPC LCPHPTC+HS+  QGVCACPEC GTLVLDPVS P WKLNCN C+C+V LP+GAHRI+TT+ +C +CDS IIE+DFNKKTTPLE+GA
Subjt:  SSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTPLEDGA

Query:  TLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF
        TL  GC+LCDE L SL+E+KHG+SF R RG RGRGRGRGRGRG      GR   K +DPKMSFRDF
Subjt:  TLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF

O95985 DNA topoisomerase 3-beta-1

6.1e-264

52.1

Show/hide

Query:  TVLMVAEKPSIALSIASALSHGQMSTRK---GSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLF-QASVIKTESNPKAHIRQHL
        TVLMVAEKPS+A SIA  LS G +S+ K   G+  VHE+ G F G    +K+TSV GHV ++DF   +  W   DP +LF QA   K E+NPK ++ + L
Subjt:  TVLMVAEKPSIALSIASALSHGQMSTRK---GSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLF-QASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECT------GFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTF
          E RGCD +VLWLDCD+EGENICFEV++          GG    K V+RARFSS+T+ DI  A+  L +P+ NEAL+VDARQE+DL++G AFTRFQT +
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECT------GFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTF

Query:  FQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYI-MQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPS
        FQGKYG+LDS LIS+GPCQTPTLGFCV+RH +I +FKPE +W +   +       L LDW+R ++FD ++  MF      +  A+V   S K++ K RP 
Subjt:  FQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYI-MQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPS

Query:  GLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATED
         LNTV +L+VASS+LG GPQ AMQ AERLYTQG+ISYPRTE+T YP +FD KG+L     +P W D V+ LL++G ++PR G D GDHPPITPM  ATE 
Subjt:  GLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATED

Query:  MLGRDAWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVN-EKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESEL
         LG DAWRLY+Y+ +HFI ++S DCKY+++ I F I  E+F C+G  V+  GFT +MPW +V  E+ LP   +G+   V  V++ +  T PPDYL+E+EL
Subjt:  MLGRDAWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVN-EKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESEL

Query:  ISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKK
        I+LMEKHGIGTDASIPVHINNI +RNYV V++GRRL PTNLGI L+ GY  ID +L LP IRS +E+Q+ L+A+G+AD+  V+ + L  FK+K+ YFV  
Subjt:  ISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKK

Query:  IDHMDALFEAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFE
        I  MD L E  FSPLA +G+ LS+CGKC R+MK+I ++P RL+CS C+E Y LPQ G IKLYKEL CPLD+FEL+++S  G  GKS+PLCPYCYN PPF 
Subjt:  IDHMDALFEAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFE

Query:  GINTLYGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPEC-SGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIE
         +                 KGMG  C  C HP+C+HSL   G+  C EC SG LVLDP S P WK+ CNKCN +    + AHR+  + + C+ C++ +++
Subjt:  GINTLYGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPEC-SGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIE

Query:  VDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKHGKS---FFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMS
        VDFNK  +PL    T  +GC+ CD     L+E+KH  S     RG    G GR +GRGRGR  R  G+ + +    KMS
Subjt:  VDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKHGKS---FFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMS

O96651 DNA topoisomerase 3-beta

2.1e-240

48.77

Show/hide

Query:  TVLMVAEKPSIALSIASALSHGQMSTRKGS---TDVHEFDGRFLGH-HAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL
        +VLMVAEKPS+A S+A  LS+G+ + ++G+      HE+ G F      H+++TSV GHV S+DF   +  W   DP+ LF  +  K E+NPK ++R+ L
Subjt:  TVLMVAEKPSIALSIASALSHGQMSTRKGS---TDVHEFDGRFLGH-HAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEI--RKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGK
        + EARGCD LVLWLDCD+EGENICFEV++      N +   +  YRA FS++TEKDI KA++ L  PN NEA +VDARQE+DL++G AFTRFQT FFQ +
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEI--RKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGK

Query:  YGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTV
        YG+LDS LISYGPCQTPTLGFCV+RH  I TFKPE FW +   ++    E+ L+W RG++F  D+  M   RV E   A V  ++ K+  K +P  LNTV
Subjt:  YGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTV

Query:  NLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRD
         L+++ SS LG GP  AMQ+AERLYTQG+ISYPRTE+  YP++FD    LH L  + ++G+  R +L D    PR G D GDHPPITPM L       RD
Subjt:  NLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRD

Query:  AWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAV-NEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLME
         WR+Y+++C+HF+G++S D KY  T  + S+  E F+CT S ++  GFT +M W A   ++  P F++G ++ +  V L +  T PPDYL+ESELI+LME
Subjt:  AWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAV-NEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLME

Query:  KHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMD
        +HGIGTDASIPVHINNI +RNYV ++ GR+L+PT LGI L+ GYQ IDP+L LP +R+ +E+ +TL+A+G A+   V+++ ++ FK K+ YFVK ID MD
Subjt:  KHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMD

Query:  ALFEAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTL
        ALFE  FSPLA+SG+A S+CGKC RYMK+I ++P RL+CS C+E Y LP  G +K+Y+E  CPLD+F+LL FS  G +G+S+P CPYCYN PPF  +  L
Subjt:  ALFEAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTL

Query:  YGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPEC-SGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNK
         G                  C  C +  C HSL T G+ +C EC +G LVLD   AP WKL CN+C+ ++   +GA +I+    KC +C +  + V +  
Subjt:  YGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPEC-SGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNK

Query:  KTTPLEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRG
          +  +DG+    GCI C      L+E KH     R   S G  RG   GRG GG G
Subjt:  KTTPLEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRG

Q0J0S6 DNA topoisomerase 3-beta

0.0e+00

73.62

Show/hide

Query:  VASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHLS
        +A TVLMVAEKPSIALSIASALS G+MSTRKGSTDVHEFDG F G HA +KVTSVIGHV S+DFP  +Q+W+ TDP+DLF A V+++E NPKAHIR+HL+
Subjt:  VASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHLS

Query:  REARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGN
        +EARGC  LVLWLDCDREGENIC+EVI+CTG   +E+ ++++RA+FSSVTEKDI+ A++NLV P+++EALAVDARQEIDLKVGVAFTRFQT +FQGKYGN
Subjt:  REARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGN

Query:  LDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNLL
        LDSR+ISYGPCQTPTLGFCVQR+ QITTFKPEKFWS+  Y++++G E+ L+W+R KLFD DVT MFQK V  DGI +VT+IS K+E K RP GLNTVNLL
Subjt:  LDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNLL

Query:  KVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAWR
        KVASSALG GPQ AM LAERLYTQGFISYPRTESTAYPSSFDF+  L +L  NP W + VR LL  G+ KP+ G D GDHPPITPM LATE+ LG DAWR
Subjt:  KVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAWR

Query:  LYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHGI
        LYQY+CQHFIG++S DC+Y RT I+F+  GE F+C G+RV  KGFTSIMPWLAV+E  +P + KG+ + + +V++Y+G+TTPPDYLSESELISLMEK+GI
Subjt:  LYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHGI

Query:  GTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALFE
        GTDASIPVH+NNI ERNYVQV +GRRLVPT LG TLIRGYQCID DLCLPDIR FIEQQITL+AKG+ADH  VVQ+VLQQF +KYSYFVKKI++MDALFE
Subjt:  GTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALFE

Query:  AQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGAA
        AQFSPLADSGR LSKCGKC RYMK+IS+QP RLYC TCEEVYYLPQ G+IKLYKE+ CPLD FELL+FS+ GP+ KSFPLCP+CYNSPPFEGI+ L+GA 
Subjt:  AQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGAA

Query:  KTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTPL
        K +  +G   KG GMPCFLC HPTC+ S+ITQGVCACPEC+GTL+LDPVSAP W+L CN+CNC+V LP  AH+ISTT++KC  C+STIIEVDFNKKTTPL
Subjt:  KTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTPL

Query:  EDGATLFVGCILCDEFLHSLLEMKHGKSFF--RGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF
        +DGATL  GCILCDE LHSL+EMKHGKSFF  RGRG RGRGRGRGRG  RG RG  R+     DPKMSFRDF
Subjt:  EDGATLFVGCILCDEFLHSLLEMKHGKSFF--RGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF

Q9Z321 DNA topoisomerase 3-beta-1

7.2e-265

52.74

Show/hide

Query:  TVLMVAEKPSIALSIASALSHGQMSTRK---GSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLF-QASVIKTESNPKAHIRQHL
        TVLMVAEKPS+A SIA  LS G MS+ K   G+  VH++ G F G   H+K+TSV GHV ++DF   +  W   DP +LF QA   K E+NPK ++ + L
Subjt:  TVLMVAEKPSIALSIASALSHGQMSTRK---GSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLF-QASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIEC---TGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQG
          E RGCD +VLWLDCD+EGENICFEV++         +   K V+RARFSS+T+ DI  A+  L +P+ NEAL+VDARQE+DL++G AFTRFQT +FQG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIEC---TGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQG

Query:  KYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYE-LNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLN
        KYG+LDS LIS+GPCQTPTLGFCV+RH +I +FKPE +W +   +  +  E L LDW+R ++FD ++  MF      +  A V   S K++ K RP  LN
Subjt:  KYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYE-LNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLN

Query:  TVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLG
        TV +L+VASSALG GPQ AMQ+AERLYTQG+ISYPRTE+T YP +FD KG+L     +P W D V+ LL++G ++PR G D GDHPPITPM  ATE  LG
Subjt:  TVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLG

Query:  RDAWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVN-EKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISL
         DAWRLY+Y+ +HFI ++S DCKY+++ I F I  E F C G  V+  GFT IMPW +V  E+ LP   KG+   V  V++ +  T+PPDYL+E+ELI+L
Subjt:  RDAWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVN-EKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISL

Query:  MEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDH
        MEKHGIGTDASIPVHINNI +RNYV V++GRRL PTNLGI L+ GY  ID +L LP IRS +E+Q+ L+A+G+AD+  V+ + L  FK+K+ YFV  I  
Subjt:  MEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDH

Query:  MDALFEAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIN
        MD L E  FSPLA +G+ LS+CGKC R+MK+I ++P RL+CS C+E Y LPQ G IKLYKEL CPLD+FEL+++S  G  GKS+PLCPYCYN PPF  + 
Subjt:  MDALFEAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIN

Query:  TLYGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPEC-SGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDF
                        KGMG  C  C HPTC+HSL   G+  C EC +G LVLDP S P WK+ CN CN +    + AHR+  + + C  C++ +++VDF
Subjt:  TLYGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPEC-SGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDF

Query:  NKKTTPLEDGATLFVGCILCDEFLHSLLEMKHGKS---FFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMS
        NK  +PL    T   GCI CD     L+E+KH  S     RG    G GR +GRGRGRG R  G+ + +    KMS
Subjt:  NKKTTPLEDGATLFVGCILCDEFLHSLLEMKHGKS---FFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMS

Arabidopsis top hits

e value

%identity

Alignment

AT2G32000.1 DNA topoisomerase, type IA, core

0.0e+00

76.44

Show/hide

Query:  VLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHLSREAR
        VLMVAEKPSIALSIAS LSHGQMSTR+GST+VHEFDG F G  AHY+VTSVIGHVFS+DFP  +Q+W T DP DLF A +IK ESNPKAHI +HLS EAR
Subjt:  VLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHLSREAR

Query:  GCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSR
        GC  +VLWLDCDREGENICFEVIE TGF   + ++KVYRARFSSVTEKDI KA+DNLV+PNR+EALAVDARQEIDLKVGVAF+RFQT++FQGKY NLD R
Subjt:  GCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSR

Query:  LISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNLLKVAS
        +ISYGPCQTPTLGFCVQR++ I TFKPEKFW++ PYI ++GYEL L+WER +LFD +   +FQK V+E   A+V ++SEKQE K RP+GLNTVNLLKVAS
Subjt:  LISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNLLKVAS

Query:  SALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAWRLYQY
        SALGFGPQ AM LAERLYTQGFISYPRTESTAYPSSFDF  TL + V NP WG YV+ LLSDG+  P+SGTD GDHPPITPM  ATE M+G DAWRLYQY
Subjt:  SALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAWRLYQY

Query:  VCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHGIGTDA
        VCQHF+G++S +CKYIRTK++ SI GE F+CTG RV  KGFT+IMPW AV+EKKLP FLKGE+IEV RVELY+GNT PPDYL+ESELISLMEKHGIGTDA
Subjt:  VCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHGIGTDA

Query:  SIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALFEAQFS
        SI VHINNIGERNYVQVQ+GR++VPT LGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHS VVQ+V+QQF++K+SYFV++I+HMDALFEAQFS
Subjt:  SIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALFEAQFS

Query:  PLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGAAKTNP
        PLADSGRALSKCGKCLRYMK I++ P RL+C TCEEVYYLPQKG +KLYKELTCPLDNFEL+I+S+PGPEGKSFPLCPYCYNSPPFEGI+TL+GA+KT  
Subjt:  PLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGAAKTNP

Query:  SSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTPLEDGA
        +   +  G GMPC LCPHPTC+HS+  QGVCACPEC GTLVLDPVS P WKLNCN C+C+V LP+GAHRI+TT+ +C +CDS IIE+DFNKKTTPLE+GA
Subjt:  SSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTPLEDGA

Query:  TLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF
        TL  GC+LCDE L SL+E+KHG+SF R RG RGRGRGRGRGRG      GR   K +DPKMSFRDF
Subjt:  TLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF

AT2G32000.2 DNA topoisomerase, type IA, core

0.0e+00

75.37

Show/hide

Query:  HVFSI---DFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDI
        H+ S+   DFP  +Q+W T DP DLF A +IK ESNPKAHI +HLS EARGC  +VLWLDCDREGENICFEVIE TGF   + ++KVYRARFSSVTEKDI
Subjt:  HVFSI---DFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDI

Query:  LKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWER
         KA+DNLV+PNR+EALAVDARQEIDLKVGVAF+RFQT++FQGKY NLD R+ISYGPCQTPTLGFCVQR++ I TFKPEKFW++ PYI ++GYEL L+WER
Subjt:  LKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWER

Query:  GKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNP
         +LFD +   +FQK V+E   A+V ++SEKQE K RP+GLNTVNLLKVASSALGFGPQ AM LAERLYTQGFISYPRTESTAYPSSFDF  TL + V NP
Subjt:  GKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNP

Query:  EWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAV
         WG YV+ LLSDG+  P+SGTD GDHPPITPM  ATE M+G DAWRLYQYVCQHF+G++S +CKYIRTK++ SI GE F+CTG RV  KGFT+IMPW AV
Subjt:  EWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAV

Query:  NEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRS
        +EKKLP FLKGE+IEV RVELY+GNT PPDYL+ESELISLMEKHGIGTDASI VHINNIGERNYVQVQ+GR++VPT LGITLIRGYQCIDPDLCLPDIRS
Subjt:  NEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRS

Query:  FIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYK
        FIEQQITLVAKGQADHS VVQ+V+QQF++K+SYFV++I+HMDALFEAQFSPLADSGRALSKCGKCLRYMK I++ P RL+C TCEEVYYLPQKG +KLYK
Subjt:  FIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYK

Query:  ELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNW
        ELTCPLDNFEL+I+S+PGPEGKSFPLCPYCYNSPPFEGI+TL+GA+KT  +   +  G GMPC LCPHPTC+HS+  QGVCACPEC GTLVLDPVS P W
Subjt:  ELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNW

Query:  KLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRG
        KLNCN C+C+V LP+GAHRI+TT+ +C +CDS IIE+DFNKKTTPLE+GATL  GC+LCDE L SL+E+KHG+SF R RG RGRGRGRGRGRG      G
Subjt:  KLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGGRGRG

Query:  RNSGKLMDPKMSFRDF
        R   K +DPKMSFRDF
Subjt:  RNSGKLMDPKMSFRDF

AT5G63920.1 topoisomerase 3alpha

1.7e-107

31.61

Show/hide

Query:  TVLMVAEKPSIALSIASALSHGQMSTRKGST---DVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHLS
        TVL VAEKPS+A S+A  LS G   TR+G +    + EFD    G      +TSVIGH+  ++F   ++ W + DP DL+QA V+K     K  I++ L 
Subjt:  TVLMVAEKPSIALSIASALSHGQMSTRKGST---DVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHLS

Query:  REARGCDCLVLWLDCDREGENICFEVIE-CTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKY-
         EAR  D LVLWLDCDREGENI FEV++ C     N     + RA FS++ ++DI +A+ NL  PN+  A AVDARQEIDL++G +FTRFQT   + ++ 
Subjt:  REARGCDCLVLWLDCDREGENICFEVIE-CTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKY-

Query:  ----GNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSV-CPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQEN-KVRPS
            G   SR+ISYGPCQ PTLGF V+R+ +I   +PE+FW++ C +  + G     +W RG LFD     +  +  +E+  A V  +   +E  K  P 
Subjt:  ----GNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSV-CPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQEN-KVRPS

Query:  GLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSD----GYSKPRSGTDVGDHPPITPMGL
         LNT+ L K AS       +  M++AE LY  GFISYPRTE+ ++ S  D +  +    ++P WG Y + LL        +    G D   HPPI P   
Subjt:  GLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSD----GYSKPRSGTDVGDHPPITPMGL

Query:  AT-EDMLGRDAWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLS
        ++ E    RD   +Y+ V +H++  +S       T ++  IAGE F+ +G  ++ K +  +  + +     +P + KG++     + L    T PP  L 
Subjt:  AT-EDMLGRDAWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLS

Query:  ESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKY-S
        E++L+S M+K GIGTDA++  HI  + +R Y    A  R  PTNLG  L+ GY  +  +L  P++R+ +E  +  V+ G+   + V++  LQQ K  +  
Subjt:  ESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKY-S

Query:  YFVKK---IDHMDALFE----AQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFP
          VKK   ++ M   FE       S    +G  + +C  C      +       +   C  + Y   + A+                   LPGP  ++  
Subjt:  YFVKK---IDHMDALFE----AQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFP

Query:  LCPYCYNSPPFEGINTLYGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKL---NCNKCNCLVFLPQGAHRIST
            C +  P      L+   +     G     +G  C        +  +   G  +  +   T    P +AP+  +   N  + N  +   Q  H  ++
Subjt:  LCPYCYNSPPFEGINTLYGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVSAPNWKL---NCNKCNCLVFLPQGAHRIST

Query:  TNEKCADCDSTIIEVDFNK--KTTPLEDGATLFVGCILCDE---FLHSLLEMKHGKSFF------------------------RGRGSRGRGRGRGRGRG
        TN     C S +     ++   T P  D +T  V C  C        +  E   G+ FF                         G  S G GR   RGRG
Subjt:  TNEKCADCDSTIIEVDFNK--KTTPLEDGATLFVGCILCDE---FLHSLLEMKHGKSFF------------------------RGRGSRGRGRGRGRGRG

Query:  RGGRGRGRNSG
        RGGRG G++SG
Subjt:  RGGRGRGRNSG

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGGTTGCTTCAACGGTTCTTATGGTGGCAGAGAAGCCTAGCATTGCGCTCTCAATTGCTTCTGCACTCTCCCATGGCCAAATGTCTACAAGAAAGGGTAGCACA
GATGTACATGAATTTGATGGGAGATTTCTTGGGCATCATGCTCATTATAAAGTGACATCAGTTATCGGACATGTTTTCAGTATAGATTTCCCTGCTGGATTTCAA
GATTGGAAGACCACTGATCCTTTGGATCTTTTTCAAGCTTCAGTAATTAAGACAGAGTCAAACCCAAAGGCGCACATACGTCAACATTTAAGTAGAGAAGCGCGT
GGTTGTGATTGTTTGGTTTTATGGTTGGATTGTGATCGTGAAGGAGAAAATATATGTTTTGAAGTTATTGAGTGCACCGGATTTGGTGGCAATGAAATTAGGAAA
AAAGTGTATCGTGCAAGGTTTTCTTCTGTTACTGAAAAAGATATTCTGAAGGCTTTGGATAACCTTGTTCAACCTAATAGAAATGAGGCACTGGCTGTTGATGCT
CGACAAGAGATAGATTTGAAAGTTGGAGTAGCCTTTACACGATTTCAAACTACCTTTTTTCAGGGAAAATATGGAAACCTTGATTCCAGACTCATCTCCTATGGG
CCATGCCAAACTCCCACGCTTGGGTTTTGTGTACAGCGTCATTTGCAAATAACTACCTTTAAGCCAGAAAAATTTTGGTCTGTGTGCCCTTATATTATGCAGAAC
GGCTATGAACTTAATCTGGACTGGGAACGGGGCAAGTTATTCGACTCTGATGTTACTGCAATGTTTCAAAAGCGAGTAATGGAAGATGGAATTGCAGAAGTAACA
GAAATATCAGAGAAGCAAGAAAACAAAGTTCGACCTTCTGGACTAAATACAGTTAACCTTCTGAAGGTTGCTTCAAGCGCACTAGGATTTGGACCTCAAATGGCA
ATGCAACTAGCTGAACGATTGTATACGCAAGGGTTCATCAGCTATCCACGTACAGAAAGTACGGCTTATCCTTCTTCGTTTGACTTCAAAGGCACTCTACATTCC
CTAGTGAAAAATCCAGAATGGGGTGATTATGTACGGATGCTTCTATCTGATGGATACAGTAAACCACGATCAGGAACTGACGTAGGTGATCATCCTCCTATTACT
CCAATGGGTTTGGCAACTGAAGATATGCTAGGGAGAGATGCTTGGAGATTGTACCAATACGTGTGTCAACACTTCATTGGGTCTCTGTCTTCTGACTGCAAGTAT
ATTAGGACGAAGATACAGTTTTCAATAGCTGGAGAAATATTCAATTGTACTGGGTCACGTGTTATGGTAAAAGGATTCACCTCCATTATGCCATGGTTGGCAGTA
AATGAAAAAAAACTACCTCAGTTTCTGAAGGGAGAGAAAATAGAAGTTGCAAGAGTGGAACTTTATCAGGGGAACACCACGCCTCCAGATTATTTGAGTGAGAGT
GAGTTGATTTCTCTCATGGAGAAGCATGGAATTGGCACAGATGCATCGATACCTGTACACATTAACAACATAGGCGAGCGCAACTATGTTCAGGTTCAAGCTGGG
AGGAGGTTGGTCCCAACTAACTTGGGCATCACCTTAATCAGAGGTTATCAATGCATTGATCCAGATCTCTGTTTACCTGATATTCGAAGTTTCATTGAGCAACAG
ATCACTCTCGTTGCCAAAGGTCAAGCAGACCATTCTAGTGTTGTGCAGAATGTATTGCAACAGTTCAAGCAAAAGTATAGCTACTTCGTTAAGAAGATTGATCAT
ATGGATGCTCTATTTGAAGCGCAATTTTCTCCCCTTGCCGATTCAGGACGTGCTTTGAGCAAATGTGGCAAATGCCTACGGTATATGAAGTTTATTTCTTCCCAA
CCACAGCGTCTGTACTGCAGTACATGTGAGGAGGTTTATTATCTTCCTCAAAAGGGAGCAATAAAGCTGTACAAGGAACTTACATGCCCTTTGGACAACTTCGAG
CTTTTGATTTTTTCCTTACCTGGCCCAGAAGGCAAGTCATTTCCTCTTTGTCCATACTGCTACAATAGTCCTCCATTTGAGGGTATTAACACATTATATGGTGCT
GCTAAAACCAATCCAAGTTCCGGAGCATCGAGCAAGGGAATGGGCATGCCATGCTTCCTGTGTCCGCACCCAACATGTCGACATTCTTTAATAACCCAAGGAGTT
TGCGCTTGCCCGGAATGTAGTGGGACACTTGTCCTAGATCCAGTGAGTGCACCCAACTGGAAACTCAACTGCAACAAGTGCAATTGTCTTGTCTTCCTTCCTCAG
GGTGCACATAGGATTTCCACCACAAATGAGAAGTGTGCTGATTGTGACTCTACAATTATAGAAGTGGACTTCAACAAGAAAACAACACCATTGGAGGATGGAGCT
ACATTGTTTGTTGGCTGCATTCTTTGTGATGAGTTTCTCCATTCACTTCTGGAAATGAAACATGGAAAATCATTTTTCAGAGGCAGAGGTTCTAGAGGAAGGGGA
AGGGGAAGGGGAAGGGGAAGGGGAAGAGGAGGAAGAGGAAGAGGACGAAATTCAGGGAAACTGATGGACCCGAAAATGAGTTTCCGAGATTTCTGA

mRNA sequence

Show/hide mRNA sequence

Protein sequence

Show/hide protein sequence

MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTDVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPAGFQDWKTTDPLDLFQASVIKTESNPKAHIRQHLSREAR
GCDCLVLWLDCDREGENICFEVIECTGFGGNEIRKKVYRARFSSVTEKDILKALDNLVQPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYG
PCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDSDVTAMFQKRVMEDGIAEVTEISEKQENKVRPSGLNTVNLLKVASSALGFGPQMA
MQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMGLATEDMLGRDAWRLYQYVCQHFIGSLSSDCKY
IRTKIQFSIAGEIFNCTGSRVMVKGFTSIMPWLAVNEKKLPQFLKGEKIEVARVELYQGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAG
RRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITLVAKGQADHSSVVQNVLQQFKQKYSYFVKKIDHMDALFEAQFSPLADSGRALSKCGKCLRYMKFISSQ
PQRLYCSTCEEVYYLPQKGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGINTLYGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGV
CACPECSGTLVLDPVSAPNWKLNCNKCNCLVFLPQGAHRISTTNEKCADCDSTIIEVDFNKKTTPLEDGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRG
RGRGRGRGRGGRGRGRNSGKLMDPKMSFRDF

CaUC05G087480 (gene) of Watermelon (USVL246-FR2) v1 genome