CuGenDBv2

Gene ID	CaUC10G192430
Organism	Citrullus amarus (Watermelon (USVL246-FR2) v1)
Description	DNA topoisomerase 2
Genome location	Ciama_Chr10:26984848..26991685
RNA-Seq Expression	CaUC10G192430
Synteny	CaUC10G192430
Gene Ontology terms	GO:0000819 - sister chromatid segregation (biological process) GO:0000712 - resolution of meiotic recombination intermediates (biological process) GO:0006265 - DNA topological change (biological process) GO:0005634 - nucleus (cellular component) GO:0046872 - metal ion binding (molecular function) GO:0005524 - ATP binding (molecular function) GO:0003918 - DNA topoisomerase type II (ATP-hydrolyzing) activity (molecular function) GO:0003677 - DNA binding (molecular function)
InterPro domains	IPR036890 - Histidine kinase/HSP90-like ATPase superfamily IPR034157 - DNA topoisomerase 2, TOPRIM domain IPR031660 - C-terminal associated domain of TOPRIM IPR020568 - Ribosomal protein S5 domain 2-type fold IPR018522 - DNA topoisomerase, type IIA, conserved site IPR014721 - Ribosomal protein S5 domain 2-type fold, subgroup IPR013760 - DNA topoisomerase, type IIA-like domain superfamily IPR013759 - DNA topoisomerase, type IIA, subunit B, C-terminal IPR013758 - DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta IPR013757 - Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily IPR013506 - DNA topoisomerase, type IIA, subunit B, domain 2 IPR006171 - TOPRIM domain IPR003594 - Histidine kinase/HSP90-like ATPase IPR002205 - DNA topoisomerase, type IIA, subunit A/C-terminal IPR001241 - DNA topoisomerase, type IIA IPR001154 - DNA topoisomerase II, eukaryotic-type

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0048368.1 DNA topoisomerase 2 [Cucumis melo var. makuwa]

0.0e+00

91.41

Show/hide

Query:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSN  NVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VFNDNMGKKSEPIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P+KSFQDYVDLYLKSAS+FQ EPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVK+YLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNPSFDSQTKETLTKR NSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATH+NGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPS+VDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRML+GE MLPMDPWYRGFSGTIEKT+TK+GGT+YT+SGIIEEVSDTTLRI+ELPVRRWT+DYKDFLDSVTRVA+KH  DKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKR LL+NLEMELLKLENKVRFILAVVN EI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
         VSNR++VDLFHELQAKGFTPFPKKTKSVEPE+AGASNETDEAEESPE VKGER+SDYEYLLAL IGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA
        LNDLD+LEKELDE+DRNDAQ ME+RKQQR+K+NNDLKPKISRNAPKAPRNSKKT N ETVTESMDTT SS+TTEVANNPVVKPKGKAAPRKAPA KKGKA
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA

Query:  AVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS--EDDDDLEIKEVAPPAAKKGGGRGGGRKA
        AV D+DD+DE+LELKDRLAAYKIESSPEPSEVSAMETEV +VQAAKKKEPSKRA  KKKTTAKSAQISIS  EDDDD EIKEV P AAKKGGGR GGRKA
Subjt:  AVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS--EDDDDLEIKEVAPPAAKKGGGRGGGRKA

Query:  AAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRS
        AAAN KTTK PAAG KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGS+LGR I EEEE+  E+E     K+MGSASSET+EEVAGF+PA GRS
Subjt:  AAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRS

Query:  QRANRTQVKYVVSDSESEAVSEDSDFDE-EASLDEE
        +RANRTQV+YV+SDS+ EAVS+DSDFDE EASLDE+
Subjt:  QRANRTQVKYVVSDSESEAVSEDSDFDE-EASLDEE

XP_008461811.1 PREDICTED: DNA topoisomerase 2 [Cucumis melo]

0.0e+00

91.41

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Query:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSN  NVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VFNDNMGKKSEPIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P+KSFQDYVDLYLKSAS+FQ EPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVK+YLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNPSFDSQTKETLTKR NSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATH+NGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPS+VDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRML+GE MLPMDPWYRGFSGTIEKT+TK+GGT+YT+SGIIEEVSDTTLRI+ELPVRRWT+DYKDFLDSVTRVA+KH  DKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKR LL+NLEMELLKLENKVRFILAVVN EI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
         VSNR++VDLFHELQAKGFTPFPKKTKSVEPE+AGASNETDEAEESPE VKGER+SDYEYLLAL IGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA
        LNDLD+LEKELDE+DRNDAQ ME+RKQQR+K+NNDLKPKISRNAPKAPRNSKKT N ETVTESMDTT SS+TTEVANNPVVKPKGKAAPRKAPA KKGKA
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA

Query:  AVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS--EDDDDLEIKEVAPPAAKKGGGRGGGRKA
        AV D+DD+DE+LELKDRLAAYKIESSPEPSEVSAMETEV +VQAAKKKEPSKRA  KKKTTAKSAQISIS  EDDDD EIKEV P AAKKGGGR GGRKA
Subjt:  AVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS--EDDDDLEIKEVAPPAAKKGGGRGGGRKA

Query:  AAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRS
        AAAN KTTK PAAG KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGS+LGR I EEEE+  E+E     K+MGSASSET+EEVAGF+PA GRS
Subjt:  AAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRS

Query:  QRANRTQVKYVVSDSESEAVSEDSDFDE-EASLDEE
        +RANRTQV+YV+SDS+ EAVS+DSDFDE EASLDE+
Subjt:  QRANRTQVKYVVSDSESEAVSEDSDFDE-EASLDEE

XP_011651769.2 DNA topoisomerase 2 [Cucumis sativus]

0.0e+00

90.28

Show/hide

Query:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSN  NVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEN++MVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFS+EFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VFNDNMGKKSEPIITKCK GDNWT+VTFKPDL KFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P++SFQDYVDLYLKSAS+ Q EPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHV+YITNQIAN+VMT VNKKNKNANVKAHNVKSYLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNPSFDSQTKETLTKR NSFGSACELTP+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATH+NGTVLSFYTMPEYE+WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPS+VDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFP+DDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRMLEGE MLPMDPWYRGFSGTIEKT+TK+GGT+YTVSGIIEEVSDTTLRI+ELPVRRWT+DYKDFLDSVTRVA+KHDKDKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKR LL+NLEMELLKLENKVRFILAVVN EI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
         VSNR++VDLFHELQAKGFTPFPKKTKSVEPE+AGASNETDEAEESPE VKGER+SDYEYLLAL IGTLTIEKVQELC+DRDKLKGEVDDLRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA
        LNDLD LEKELDEMDRNDAQ ME+RKQQREK+N DLKPK+SRNAPKAPRNSKKT N ETVTESMDTT SS+TTEVANNPVVKPKGKAAPRKAPA KKGKA
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA

Query:  AVLD---DDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQV--QAAKKKEPSKRAAPKKKTTAKSAQISISEDDD--DLEIKEVAPPAAKKGGGR-
        AVLD   DD++DE+LELKDRLAAYKIESSPEPSEVSAMETEV +V  QAAKKKEPSKRA  KKKTTAKSAQISIS+DD+  D EIKEV PPAAKKGGGR 
Subjt:  AVLD---DDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQV--QAAKKKEPSKRAAPKKKTTAKSAQISISEDDD--DLEIKEVAPPAAKKGGGR-

Query:  GGGRKAAAANAKTTKPPAAGVKLGQKLITQMLEP-AENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETTEEVAGF
        GGGRKAAA N+KTTKPPAAG KLGQKLITQMLEP AENSGISPEKKVRKIRASPFNKKSGS+LGRTIGEEEE+E ++E     KLMGSAS ET+EEV   
Subjt:  GGGRKAAAANAKTTKPPAAGVKLGQKLITQMLEP-AENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETTEEVAGF

Query:  RPARGRSQRANR-TQVKYVVSDSESEAVSEDSDFDE-EASLDEE
        + ARGRS+RANR TQV+YV+SDS+ E  S+DSDFDE EASLDE+
Subjt:  RPARGRSQRANR-TQVKYVVSDSESEAVSEDSDFDE-EASLDEE

XP_022935016.1 DNA topoisomerase 2 isoform X2 [Cucurbita moschata]

0.0e+00

89.42

Show/hide

Query:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSN  NVDS+PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VF+DNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P+KSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNP+FDSQTKETLT R +SFGSACELTP+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD++DGEAIELAFSKKKIE+RKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMADLQRSIPS+VDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRML GE MLPMDPWYRGFSGTIEKT+TK+GGTSYTVSGIIEEVSDTTLRI ELPVRRWTNDYKDFLDSVTRV+TK+DKDKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        K VSIDVHLTEENM+LA+QEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKVRFILAVVNGEI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
        IVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNETDEAEESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEV++LRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMD--TTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKA
        L DLD LEKELDEMDRNDAQA E+RKQQR K NND+KPKISRNAPKAPRNSKKT N+ET+TESMD  T+SS+TTEVANNPVVKPKGKAAPRKAPAKKGK 
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMD--TTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKA

Query:  AVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQ-AAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAA
        AVLDDDD+DE+LELKDRLAAYK+ESSPEPSEVSAMETEVP+VQ AAKKKEPSKRAA KKKTTAKSAQIS   DD D EIKE+APPAAKKGGGR      A
Subjt:  AVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQ-AAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAA

Query:  AANAKTTK-----PPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETT-EEVAGFRP
        AANAKTTK      P A  +LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR IG  EEEEE EEAGNE K+MGSASSETT EEVA    
Subjt:  AANAKTTK-----PPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETT-EEVAGFRP

Query:  ARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEE
        ARGRSQR NRTQV+YVVSDS+SE V EDSDFDEEA+LDE+
Subjt:  ARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEE

XP_038905935.1 DNA topoisomerase 2 [Benincasa hispida]

0.0e+00

91.46

Show/hide

Query:  MAVEKKRPLQNSNVTNVDSNP-AGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSM
        MAVEKKRPLQNSN  NVDS+P AGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHRS+SYVPGLYKIFDEILVNAADNKQRDPSM
Subjt:  MAVEKKRPLQNSNVTNVDSNP-AGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSM

Query:  DSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTN
        DSVKV+IDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQ          
Subjt:  DSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTN

Query:  CSVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQR
                                     VFNDNMGKKSEPIITKCK GDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQR
Subjt:  CSVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQR

Query:  VPIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWV
        VPIKSFQDYVDLYLKSASTFQTEPPKRYHIKPN+RWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQI+NYVMT VNKKNKNANVKAHNVK+YLWV
Subjt:  VPIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWV

Query:  FINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG
        FINALIDNPSFDSQTKETLTKR NSFGS CELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG
Subjt:  FINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG

Query:  DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL
        DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA+SKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL
Subjt:  DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL

Query:  KVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRK
        +VPSFLVEFITPIVKATH+NGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRK
Subjt:  KVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRK

Query:  NWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQD
        NWLRQFEPGTHLDQT KLIKYSDFVNKELILFSMADLQRSIPS+VDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQD
Subjt:  NWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQD

Query:  FVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIR
        FVGSNNINLLLPNGQFGTRN GGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDII+
Subjt:  FVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIR

Query:  NVRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSD
        NVRRML+G  MLPMDPWYRGFSGTIEKT+TK+GGTSYTVSGIIEEVSDT LRI+ELPVRRWTNDYKDFLDSVT+VATKHDKDKEKAAK+PFIEQADHHSD
Subjt:  NVRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSD

Query:  DKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGE
        DKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRL+FYEKRKRNLLENLEMELLKLENKVRFIL VVN E
Subjt:  DKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGE

Query:  IIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSL
        IIV NRR+VDLFHELQAKGFTPFPKK KSVEPEVAGAS+E DEAEESPE VK  RVSDYEYLL+L IGTLTIEKVQELCN+RDKLKGEVDDLRKATPK+L
Subjt:  IIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSL

Query:  WLNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSSSTT-EVANNPVVKPKGKAAPRKAPAKKGKA
        WLNDLD+LEKELDEMD NDAQAME RK+QR+K NNDLKPKISRNAPKAPRN KKT NAE VTESMDTT SSTT EVANNPVVKPKGKAAPRKAPAKKGKA
Subjt:  WLNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSSSTT-EVANNPVVKPKGKAAPRKAPAKKGKA

Query:  AVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS-----EDDDDLEIKEVAPPAAKKGGGRGGG
        AVLDDDD DE+LELKDRLAAYKIESSPEPSEVS METEVPQVQAAKKKEP+KRAA KKKTTAKSAQ+S+S     +DDDD E+KEVAPPA KKGGGRGGG
Subjt:  AVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS-----EDDDDLEIKEVAPPAAKKGGGRGGG

Query:  RKAAAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEE-EEEEEEEEAGNEEKLMGSASSETT-EEVAGFRP
        RKAAA NAKTTKPPAA  KLGQKLIT+MLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEE EEEEEEEE+G EEK+MGSASSETT EEVAG  P
Subjt:  RKAAAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEE-EEEEEEEEAGNEEKLMGSASSETT-EEVAGFRP

Query:  ARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEE
        ARGRS RANRTQV+YVVSD +SE VSEDSD DE+
Subjt:  ARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEE

TrEMBL top hits

e value

%identity

Alignment

A0A1S3CFK5 DNA topoisomerase 2

0.0e+00

91.41

Show/hide

Query:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSN  NVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VFNDNMGKKSEPIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P+KSFQDYVDLYLKSAS+FQ EPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVK+YLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNPSFDSQTKETLTKR NSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATH+NGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPS+VDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRML+GE MLPMDPWYRGFSGTIEKT+TK+GGT+YT+SGIIEEVSDTTLRI+ELPVRRWT+DYKDFLDSVTRVA+KH  DKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKR LL+NLEMELLKLENKVRFILAVVN EI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
         VSNR++VDLFHELQAKGFTPFPKKTKSVEPE+AGASNETDEAEESPE VKGER+SDYEYLLAL IGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA
        LNDLD+LEKELDE+DRNDAQ ME+RKQQR+K+NNDLKPKISRNAPKAPRNSKKT N ETVTESMDTT SS+TTEVANNPVVKPKGKAAPRKAPA KKGKA
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA

Query:  AVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS--EDDDDLEIKEVAPPAAKKGGGRGGGRKA
        AV D+DD+DE+LELKDRLAAYKIESSPEPSEVSAMETEV +VQAAKKKEPSKRA  KKKTTAKSAQISIS  EDDDD EIKEV P AAKKGGGR GGRKA
Subjt:  AVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS--EDDDDLEIKEVAPPAAKKGGGRGGGRKA

Query:  AAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRS
        AAAN KTTK PAAG KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGS+LGR I EEEE+  E+E     K+MGSASSET+EEVAGF+PA GRS
Subjt:  AAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRS

Query:  QRANRTQVKYVVSDSESEAVSEDSDFDE-EASLDEE
        +RANRTQV+YV+SDS+ EAVS+DSDFDE EASLDE+
Subjt:  QRANRTQVKYVVSDSESEAVSEDSDFDE-EASLDEE

A0A5A7TZH5 DNA topoisomerase 2

0.0e+00

91.41

Show/hide

Query:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSN  NVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VFNDNMGKKSEPIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P+KSFQDYVDLYLKSAS+FQ EPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVK+YLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNPSFDSQTKETLTKR NSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATH+NGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPS+VDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRML+GE MLPMDPWYRGFSGTIEKT+TK+GGT+YT+SGIIEEVSDTTLRI+ELPVRRWT+DYKDFLDSVTRVA+KH  DKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKR LL+NLEMELLKLENKVRFILAVVN EI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
         VSNR++VDLFHELQAKGFTPFPKKTKSVEPE+AGASNETDEAEESPE VKGER+SDYEYLLAL IGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA
        LNDLD+LEKELDE+DRNDAQ ME+RKQQR+K+NNDLKPKISRNAPKAPRNSKKT N ETVTESMDTT SS+TTEVANNPVVKPKGKAAPRKAPA KKGKA
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA

Query:  AVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS--EDDDDLEIKEVAPPAAKKGGGRGGGRKA
        AV D+DD+DE+LELKDRLAAYKIESSPEPSEVSAMETEV +VQAAKKKEPSKRA  KKKTTAKSAQISIS  EDDDD EIKEV P AAKKGGGR GGRKA
Subjt:  AVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS--EDDDDLEIKEVAPPAAKKGGGRGGGRKA

Query:  AAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRS
        AAAN KTTK PAAG KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGS+LGR I EEEE+  E+E     K+MGSASSET+EEVAGF+PA GRS
Subjt:  AAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRS

Query:  QRANRTQVKYVVSDSESEAVSEDSDFDE-EASLDEE
        +RANRTQV+YV+SDS+ EAVS+DSDFDE EASLDE+
Subjt:  QRANRTQVKYVVSDSESEAVSEDSDFDE-EASLDEE

A0A6J1F3D6 DNA topoisomerase 2

0.0e+00

89.42

Show/hide

Query:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSN  NVDS+PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VF+DNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P+KSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNP+FDSQTKETLT R +SFGSACELTP+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD++DGEAIELAFSKKKIE+RKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMADLQRSIPS+VDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRML GE MLPMDPWYRGFSGTIEKT+TK+GGTSYTVSGIIEEVSDTTLRI ELPVRRWTNDYKDFLDSVTRV+TK+DKDKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        K VSIDVHLTEENM+LA+QEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKVRFILAVVNGEI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
        IVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNETDEAEESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEV++LRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMD--TTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKA
        L DLD LEKELDEMDRNDAQA E+RKQQR K NND+KPKISRNAPKAPRNSKKT N+ET+TESMD  T+SS+TTEVANNPVVKPKGKAAPRKAPAKKGK 
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMD--TTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKA

Query:  AVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQ-AAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAA
        AVLDDDD+DE+LELKDRLAAYK+ESSPEPSEVSAMETEVP+VQ AAKKKEPSKRAA KKKTTAKSAQIS   DD D EIKE+APPAAKKGGGR      A
Subjt:  AVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQ-AAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAA

Query:  AANAKTTK-----PPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETT-EEVAGFRP
        AANAKTTK      P A  +LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR IG  EEEEE EEAGNE K+MGSASSETT EEVA    
Subjt:  AANAKTTK-----PPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETT-EEVAGFRP

Query:  ARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEE
        ARGRSQR NRTQV+YVVSDS+SE V EDSDFDEEA+LDE+
Subjt:  ARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEE

A0A6J1F9E0 DNA topoisomerase 2

0.0e+00

89.36

Show/hide

Query:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSN  NVDS+PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VF+DNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P+KSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNP+FDSQTKETLT R +SFGSACELTP+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD++DGEAIELAFSKKKIE+RKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMADLQRSIPS+VDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRML GE MLPMDPWYRGFSGTIEKT+TK+GGTSYTVSGIIEEVSDTTLRI ELPVRRWTNDYKDFLDSVTRV+TK+DKDKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        K VSIDVHLTEENM+LA+QEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKVRFILAVVNGEI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
        IVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNETDEAEESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEV++LRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMD--TTSSSTTEVANNPVVKPKGKAAPRKAPAKK-GK
        L DLD LEKELDEMDRNDAQA E+RKQQR K NND+KPKISRNAPKAPRNSKKT N+ET+TESMD  T+SS+TTEVANNPVVKPKGKAAPRKAPAKK GK
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMD--TTSSSTTEVANNPVVKPKGKAAPRKAPAKK-GK

Query:  AAVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQ-AAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKA
         AVLDDDD+DE+LELKDRLAAYK+ESSPEPSEVSAMETEVP+VQ AAKKKEPSKRAA KKKTTAKSAQIS   DD D EIKE+APPAAKKGGGR      
Subjt:  AAVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQ-AAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKA

Query:  AAANAKTTK-----PPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETT-EEVAGFR
        AAANAKTTK      P A  +LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR IG  EEEEE EEAGNE K+MGSASSETT EEVA   
Subjt:  AAANAKTTK-----PPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETT-EEVAGFR

Query:  PARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEE
         ARGRSQR NRTQV+YVVSDS+SE V EDSDFDEEA+LDE+
Subjt:  PARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEE

A0A6J1J555 DNA topoisomerase 2

0.0e+00

89.29

Show/hide

Query:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVE KRPLQNSN  NVDS+PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLW+YEND+MVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        S+KV ID EQNCISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VF+DNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P+KSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNP+FDSQTKETLT R +SFGSACELTP+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD++DGEAIELAFSKKKIE+RKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMADLQRSIPS+VDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRML+GE MLPMDPWYRGFSGTIEKT+TK+GGTSYTVSGIIEEVSDTTLRI ELPVRRWTNDYKDFLDSVTRV+TK+DKDKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        K VSI+VHLTEENM+LA+QEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKVRFILAVVNGEI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
        IVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNETDEAEESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEV++LRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMD--TTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKA
        L DLD LEKELDEMDRNDAQA E+RKQQR K NND+KPKISRNAPKAPRNSKKT N+ET+TESMD  T+SS+TTEVANNPVVKPKGKAAPRKAPAKKGKA
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMD--TTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKA

Query:  AVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQ-AAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAA
        AVLDDD +DE+LELKDRLAAYK+ESSPEPSEVSAMETEVP+VQ AAKKKEPSKRAA KKKTTAKSAQIS   DD D EIKE+APPAAKKGGGR      A
Subjt:  AVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQ-AAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAA

Query:  AANAKTTK-----PPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETT-EEVAGFRP
        AANAKTTK      P A  +LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR IG  EEEEE EEAGNE K+MGSASSETT EEVA    
Subjt:  AANAKTTK-----PPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETT-EEVAGFRP

Query:  ARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEE
        ARGRSQR NRTQV+YVVSDS+SE V EDSDFDEEA LDE+
Subjt:  ARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEE

SwissProt top hits

e value

%identity

Alignment

O24308 DNA topoisomerase 2

0.0e+00

61.47

Show/hide

Query:  KKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKV
        +KRPLQ SN  N+      P KTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYEND MVHR++SYVPGLYKIFDEILVNAADNKQRDPSMDS+KV
Subjt:  KKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKV

Query:  NIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNCSVDF
         ID E N +SV+NNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADG+R+KKYKQ               
Subjt:  NIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNCSVDF

Query:  ELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIKS
                                VF++NMG K EP+ITKCK  +NWTKVTFKPDL KF M +LE+DVVALMKKRVLD+AGC GKTVKVELNG  +  KS
Subjt:  ELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIKS

Query:  FQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINAL
        F+DY DL+LK A   +  P  R H K  +RWEI ++LS+GQFQQVSFVN I+TIKGGTHVDYITNQI  Y+M  VNKK K+ANVKAH VK++LWVF+N+L
Subjt:  FQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINAL

Query:  IDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKA
        IDNP+FDSQTKETLT R  SFGS C++    LK+V  KSGI+D++LSW +FKQSKDLKKTDG KT+++ G  K EDAN AGG+NSEKCTLILTEGDSAKA
Subjt:  IDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKA

Query:  LAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSF
        LAMAGL VVGRD YGVFPLRGKLLNVREASSKQI +N+EIQ IK+ILGLQQ KEY+N K+LRYGHLMIM DQDHDGSHIKGLLINFIHSFWPSLLKVPSF
Subjt:  LAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSF

Query:  LVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQ
        LVEF TP+++A+H N T+ SFY+MPEYE+WKE L  +A+ W IKYYKGLGTST +EGREYF  L +H+KDFIW D+ DG AIELAFSKKK E RK W+R 
Subjt:  LVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQ

Query:  FEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSN
        FEPGT  D   KLI Y DFVNKELILFS AD                   LF SFK+   KE KV+QF GYVSEHSAYHHGEQSLASTIIGMAQDFVGSN
Subjt:  FEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSN

Query:  NINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRM
        NINLL PNGQFGT N GGKDHAS+RYIYT+LS VTR LF + DDKLL YLNEDG+SIEP WYMPIIP VLVNGSEGIGTGWSSY+PNYNPR+II NVRR+
Subjt:  NINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRM

Query:  LEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDDKIVS
        L GE ++PMDPWY+GF GTIEK S K+GG  Y V+G + E+ + T RI ELP+R+WT DYK FL+S+T        D     KDP IE    + DD IV 
Subjt:  LEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDDKIVS

Query:  IDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSN
        I++ +  E +   +QEGL KKFKLT+T+STSNMHLFDA G  KK+DTPEQILEEFFPLRL++YEK K  +L NL   LL L+NKVRFIL VVNGEIIVSN
Subjt:  IDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSN

Query:  RRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPE--------AVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATP
        R++ +L  EL+ KGFTP P+K KS +P+VAGA+++  E +E  E        +V+G    DY+ LL+L IGTLT+E VQ+L +++ + + E + L     
Subjt:  RRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPE--------AVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATP

Query:  KSLWLNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSSSTTEVAN-NPVVKPKGKAAPRKAPAKK
         SLWL DLD  EK+LDE+D   A+    R  Q  K  N    K ++  P+  +N+KK  + E   ++      +  E A    V KPKG+AAP+K     
Subjt:  KSLWLNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSSSTTEVAN-NPVVKPKGKAAPRKAPAKK

Query:  GKAAVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTT-------AKSAQISISEDDDDL-EIKEVAPPAAKKG
             +  + ED+I  L++RLAAY IESS E S+  AME+E  Q +AA KK+ +KR   KKK++       + +    + +DDDD  E+++ A P  K  
Subjt:  GKAAVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTT-------AKSAQISISEDDDDL-EIKEVAPPAAKKG

Query:  GGRGGGRKAAAANAK------TTKPPAAGVK--------LGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEE-EAGNEE
            GGRK AA NAK        K PAA  K         GQKL+T ML+PAE +G SPEKKVRK+R SPFNKKSGSILGR    ++     +  AG+  
Subjt:  GGRGGGRKAAAANAK------TTKPPAAGVK--------LGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEE-EAGNEE

Query:  KLMGSASSETTEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED
              S +   E+A  +PAR R QRANRTQ+KY +S+SESE   EDSD D E S  EED
Subjt:  KLMGSASSETTEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED

O42131 DNA topoisomerase 2-beta

0.0e+00

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Query:  NVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEND-RMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQNCIS
        +V+ N    K ++E +YQKK+QLEHILLRPDTY+GS+E  TQ +WVY+ D  M  R +++VPGLYKIFDEILVNAADNKQRD +M  +K++ID E N IS
Subjt:  NVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEND-RMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQNCIS

Query:  VFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNCSVDFELILSCMFDS
        ++NNG G+PV  H+ EKVYVP LIFG LLTSSNYDD EKK TGGRNGYGAKL NIFST+F +ETA     K+YK                          
Subjt:  VFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNCSVDFELILSCMFDS

Query:  YSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIKSFQDYVDLYLK
        +SF +          + +NM K SEP I K  EGD++T +TF+PDL+KF M +L+ D+V+LM +R  DLAG   K VKV LNG+++P+  F+ YVDLY+K
Subjt:  YSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIKSFQDYVDLYLK

Query:  SASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNK-NANVKAHNVKSYLWVFINALIDNPSFDSQ
                  K  H   NERW++ +TLSE  FQQ+SFVN I+T KGG HVDY+ +Q+   ++ VV KKNK   +VK   VK+++WVF+N LI+NPSFDSQ
Subjt:  SASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNK-NANVKAHNVKSYLWVFINALIDNPSFDSQ

Query:  TKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGV
        TKE +T +P SFGS C+L+ +F K  A+  GI++S+L+WV FK    L KK    K  KI GI KL+DAN AGGK+S  CTLILTEGDSAK+LA++GLGV
Subjt:  TKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGV

Query:  VGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY---SNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFI
        +GRD YGVFPLRGK+LNVREAS KQI EN EI  I +I+GLQ  K Y    + K+LRYG +MIMTDQD DGSHIKGLLINFIH  WPSLLK   FL EFI
Subjt:  VGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY---SNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFI

Query:  TPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFE---
        TPIVKA+ +N   LSFY++PE++ WK+ +  N   W IKYYKGLGTST+KE +EYF  + +H+  F +    D  AI LAFSKKKI+DRK WL  F    
Subjt:  TPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFE---

Query:  --------PGTHLDQTG-KLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA
                P   L  T  K + Y+DF+NKELILFS +D +RSIPS+VDGLKPGQRK+LF  FKRN  +E KV+Q +G V+E SAYHHGEQ+L  TI+ +A
Subjt:  --------PGTHLDQTG-KLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA

Query:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI
        Q+FVGSNN+NLL P GQFGTR HGGKD AS RYI+T LS + R LFP  DD LL +L +D Q +EP WY+PIIP VLVNG+EGIGTGW+  +PNY+ R+I
Subjt:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI

Query:  IRNVRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHH
        + NVRRML+G    PM P Y+ F GTI++     G   Y VSG I  V   T+ I ELPVR WT  YK+      +V        EK      I     +
Subjt:  IRNVRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHH

Query:  SDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVN
          D  V   V +TEE +  A   GL K FKL T+++ ++M LFD  G +KKY+T + IL+EFF LRL +Y  RK  L+  L  E  KL N+ RFIL  + 
Subjt:  SDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVN

Query:  GEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVS-DYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATP
        G+I + NR + DL   L  +G+   P K      E A    +   A +   +  G     D+ Y+L +++ +LT EKV+EL   RD  + E++DL++ + 
Subjt:  GEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVS-DYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATP

Query:  KSLWLNDLDALEKELDEM---DRNDAQAMEIRKQQREKSNNDLKPKISR
          LW  DL A  +EL+++   +R D  A  + K  + K     KPK+ +
Subjt:  KSLWLNDLDALEKELDEM---DRNDAQAMEIRKQQREKSNNDLKPKISR

P08096 DNA topoisomerase 2

0.0e+00

46.43

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Query:  SNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVY--ENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQNCISVF
        +N       +   YQ+ +  EH+L RPDTY+GSIE  T  +WV+  E +++ +++++YVPGLYKIFDEI+VNAADNK RDP+M+++KV +D E N IS++
Subjt:  SNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVY--ENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQNCISVF

Query:  NNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNCSVDFELILSCMFDSYS
        NNG G+P+EIH +EK+Y+PELIFG+LLTSSNYDD +KK TGGRNGYGAKL NIFSTEFV+ETAD +RMKKYKQ                           
Subjt:  NNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNCSVDFELILSCMFDSYS

Query:  FAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIKSFQDYVDLYLKSA
                     + DNM +KSEP+IT  K+ D +TK+TFKPDLAKF M  ++DD+V+++K+R+ D+AG + +T KV LN +R+ I  F+ YV++YL S 
Subjt:  FAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIKSFQDYVDLYLKSA

Query:  STFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKE
        +    EPP+  +   N+RW++   +S+GQF+QVSFVN ISTI+GGTHV+Y+ N+I + +  VV K+NK A VKA  +K+Y+ VF+N  I+NPSFDSQTKE
Subjt:  STFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKE

Query:  TLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRD
        TLT + ++FGS C L+ +FLK +  KS +++ VL +   K  + L K DG    +I+G+ KLEDAN AG K S KC LILTEGDSAK+LA++GL VVGRD
Subjt:  TLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRD

Query:  FYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKAT
        +YGVFPLRGKLLNVREAS  QI  NKEIQ IK+I+G    K Y++ K LRYGHLMIMTDQDHDGSHIKGL+IN++ S +PSLL++P FL++FITPI+K T
Subjt:  FYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKAT

Query:  HRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGK
         R   V +FYT+PEYE WKE+   N  GW IKYYKGLGTS   + + YF  L +H K F    + D E IE+AF+KKK + RK WLR + PG ++D T  
Subjt:  HRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGK

Query:  LIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFG
         I   DF+N+ELI FSMAD  RSIPSVVDGLKPGQRK+++  FKRN V E KVS+ +GYV+  +AYHHGE S+  TI+ +AQ+FVGSNNINLL+PNGQFG
Subjt:  LIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFG

Query:  TRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGEMMLPMDPW
        TR+ GGK+ ++SRY+ T LS + R LF  +DD+LLNY N++GQ IEP +Y+PI+P VLVNG+EGIGTGWS+++PNYNP+DI  N+R ML GE +  M PW
Subjt:  TRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGEMMLPMDPW

Query:  YRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLL
        YRGF G+I    TK     Y +SGII ++ +  + I ELP+R WT D K++L++   V T      EK  K  FI   + H  +  V  +V LTE  M  
Subjt:  YRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLL

Query:  AIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQA
        A+ E L+ KFKL+ T +TSNM  FDA+G IKKYD+ E IL EF+ +RL  Y++RK +++  LE    +  N+ RFI  ++ GE++VS +++ DL  EL+ 
Subjt:  AIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQA

Query:  KGFTPF--PKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDALEKELDEM
        K F P   PKK   V+ EV    N   E E+S +  + E    Y YLL++ + +LT E+  EL   +D++  E+D L K TPK LWL+DLDA E   +++
Subjt:  KGFTPF--PKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDALEKELDEM

Query:  DRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKAAVLDDDDEDEILELKD
          +D Q   + ++Q  +   +   K  R      R  +    + + T      SS +     N   +   + A  K P K     ++  +D    L +++
Subjt:  DRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKAAVLDDDDEDEILELKD

Query:  RLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAP------KKKTTAKSAQISISEDDDDLEIKEVAPP--AAKKGGGRGGGRKAAAANAKTTKP
           +         S  S   ++    + A  K+P K+ A       +K     +  I  S+D+DDL    + P    + K   +  G+KA++   ++ + 
Subjt:  RLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAP------KKKTTAKSAQISISEDDDDLEIKEVAPP--AAKKGGGRGGGRKAAAANAKTTKP

Query:  P-----AAGVKLGQKLITQMLEPAENSGISPEKKVRKIRAS
                G     K  +   EP E+S  SP +K    RA+
Subjt:  P-----AAGVKLGQKLITQMLEPAENSGISPEKKVRKIRAS

P30182 DNA topoisomerase 2

0.0e+00

61.06

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Query:  KRPLQNSNVTNVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSN  NV   PA  +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ LWVYE D MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNVTNVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADGKR+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VF +NMGKKSEP+ITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWV
        P+KSF DYVDLYL +A+  +TE P  R   K N+RWE+ V+LSEGQFQQVSFVN I+TIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWV
Subjt:  PIKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWV

Query:  FINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG
        F+NALIDNP+FDSQTKETLT R +SFGS CEL+ +FLK V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEG
Subjt:  FINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG

Query:  DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL
        DSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QIT NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL
Subjt:  DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL

Query:  KVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIED
        +VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WKESL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE 
Subjt:  KVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIED

Query:  RKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA
        RKNWL  + PG HLDQ    + YSDFVNKELILFSMADLQRSIPS+VDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMA
Subjt:  RKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA

Query:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI
        QD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I
Subjt:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI

Query:  IRNVRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHH
        + NVRR+L GE M+PMDPWYRGF GTIEKT++K+GG +YT++G+ EEV +TT+RI ELP+RRW +DYK+FL S+     K D         PF +    +
Subjt:  IRNVRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHH

Query:  SDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVN
        +D+K V  D+ L+EENML A QEG  KKFKLTTT++TSNMHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  +++N+E+ELLKLENK RFILAV++
Subjt:  SDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVN

Query:  GEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERV--------SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVD
        GEIIV+ R++ D+  +L+ KGFTPFP+K +SVE  +AGA +  D+A E PE +  +          S+Y+YLLA+AI +LTIEKV+EL  DRDK+   V 
Subjt:  GEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERV--------SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVD

Query:  DLRKATPKSLWLNDLDALEKELDEMDRNDAQAMEI--RKQQREKSNNDLKPKISRNAPKAP---RNSKKTINAETVTES---MDT---------------
        D++K TPKSLWL+DL++L+KEL+++D  DAQ  +     Q++ ++ +    K+ R APK P   + +KK   +ET   S   MDT               
Subjt:  DLRKATPKSLWLNDLDALEKELDEMDRNDAQAMEI--RKQQREKSNNDLKPKISRNAPKAP---RNSKKTINAETVTES---MDT---------------

Query:  -----TSSSTTEVANN---------PVVKPKGKAAPRKAPAKKGKAAVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRA
             + S TTE +++          VVKPKG+       AKK   A   + +EDE+L+L  RLA Y   S+P                           
Subjt:  -----TSSSTTEVANN---------PVVKPKGKAAPRKAPAKKGKAAVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRA

Query:  APKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAAAANAKTTKPPAAGVKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPFNKKSGS
        A   KT   S  I++ +DDDD+ + EVAP   KK     GGRK AA   K  KPPAA  K G++ +  T++L      G+SPEKKVRK+R+SPFNKKS S
Subjt:  APKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAAAANAKTTKPPAAGVKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPFNKKSGS

Query:  ILGRTIGEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED
        ++ R    +EEE  E  AGN           ++E+  G   A  R QRANR ++ YV+SDSESE+ + DS+FD+    DE+D
Subjt:  ILGRTIGEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED

Q55BP5 Probable DNA topoisomerase 2

0.0e+00

45.69

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Query:  EKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVK
        +K     N NV    ++ A   K+IEE+YQKK  L+ ILLRPDTY+GS E+  + LWV+E+ RMVHR +S+VPG+YKIFDEILVNAADNKQR+ +M  +K
Subjt:  EKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVK

Query:  VNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNCSVD
        V ID E+  ISV N+G G+P+++H E K+Y+PELIFG+LLTSS+YDD+EK+ TGGRNG+GAKL NIFST+F++E AD K  K YKQ              
Subjt:  VNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNCSVD

Query:  FELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIK
                                  F +NM  K +P IT  +   ++TK+TF P+L +F M   +DD+VAL+ KRV D+AGC   T+KV LN + + I+
Subjt:  FELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIK

Query:  SFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLS-EGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNK-NANVKAHNVKSYLWVFI
        SF+ Y++LY       +   PK Y+ K ++RWE+ VTLS E QF QVSFVN I T+KGGTHV +  + I   +   VNKKNK +A++K   +K++L VF+
Subjt:  SFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLS-EGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNK-NANVKAHNVKSYLWVFI

Query:  NALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVA-TKSGIMDSVLSWVNFKQSKDLKK--TDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTE
        N LI+NP FDSQTKETLT + +SFGS CE + +F+K V  +KSGI+ S+L +  FK    LK+  + G K  K+S I KL+DAN AGG  SE CTLILTE
Subjt:  NALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVA-TKSGIMDSVLSWVNFKQSKDLKK--TDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTE

Query:  GDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSL
        GDSAK+LA AG+ VVG+D YG FPL+GKLLNVR+ S+K +  N EI  I  ILGL+ GK Y     LRYGHLMIMTDQDHDGSHIKGL+IN +H FWP+L
Subjt:  GDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSL

Query:  LKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDR
        L++P FLVEFITPIVK    N   +SFYTMPE+  W+E+   N  GW +KYYKGLGTST  EG+EYF  L +HK DF W D+   + IELAFSK + +DR
Subjt:  LKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDR

Query:  KNWLRQFEPGTHLDQTG-KLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA
        K W+ +   GT L+Q G K + YSDF+NKEL+LFS+AD +RSIP++VDGLK   RK L+  FKRN  KE KV+Q  GYVSEHSAYHHGE SL STI+GMA
Subjt:  KNWLRQFEPGTHLDQTG-KLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA

Query:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI
        Q+FVGSNNINLL P G +GTR  GGKD +S+RYI+T+L+++ R ++  DDD +L+ + +DG+ ++P +Y+P+IP +LVNG  GIGTGWSS +PNYNPRD+
Subjt:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI

Query:  IRNVRRMLEGEMMLPMDPWYRGFSGTIE-KTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSV----TRVATKHDKDKEKA------A
        I+N+R  ++G+ + P+ PWYRGF G+IE    +K  G  Y   GI +++SD    I ELP+  WT DY++ LD +    TR   K +K+K+ A      A
Subjt:  IRNVRRMLEGEMMLPMDPWYRGFSGTIE-KTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSV----TRVATKHDKDKEKA------A

Query:  KDPFIEQADHHSDD----KIVSIDV------------HLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKR
        K    +++    DD    K+    V            H   + +    +  ++K FKL +T++ +NM +FD  G I+++ T   + E FFPLR++ Y+ R
Subjt:  KDPFIEQADHHSDD----KIVSIDV------------HLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKR

Query:  KRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKK--TKSVEPEVAGASNETDE------AEESPEAVKGERVSD---YE
        K  L E L  E  +L NK RFILAVVN E+++SN ++VDL ++L+   F     K   KS   ++    N  DE      ++E  +  + E+  D   Y+
Subjt:  KRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKK--TKSVEPEVAGASNETDE------AEESPEAVKGERVSD---YE

Query:  YLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDALEKELDEMDRNDA----QAMEIRKQQREKS---NNDLKPKISRNAPKAPRNS-
        YLL+L + +LT+E+V++L  +RD  K E D L     + ++  DLDALEK LD+ D  D     Q   ++K+ + K+      +  K+ ++  +AP    
Subjt:  YLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDALEKELDEMDRNDA----QAMEIRKQQREKS---NNDLKPKISRNAPKAPRNS-

Query:  -KKTINAETVTESM----------DTTSSSTTEVANN---PVVKPKGKAAPRKAPA-KKGKAAVLDDD---DEDEILELKDRLAAYKIESSPEPSEVSAM
         K T+   T T+S           DTTS+ST+   ++   P+     K   +  PA KK     LD D   D+D ++  K +    K     E S+ S  
Subjt:  -KKTINAETVTESM----------DTTSSSTTEVANN---PVVKPKGKAAPRKAPA-KKGKAAVLDDD---DEDEILELKDRLAAYKIESSPEPSEVSAM

Query:  ETEVPQVQAAKKKEPSKRA----------APKKKTTAKSAQISISEDDDDL
        E++    Q +  + P KR+          A KK TT+KS  I     DD++
Subjt:  ETEVPQVQAAKKKEPSKRA----------APKKKTTAKSAQISISEDDDDL

Arabidopsis top hits

e value

%identity

Alignment

AT3G10270.1 DNA GYRASE B1

3.5e-20

23.2

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Query:  GLYKIFDEILVNAADNKQRDPSMDSVKVNIDV---EQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFS
        GL+ +  EIL NA D  Q           IDV     + +S+ +NG G+P ++H        E +   L     +         +GG +G G  + N  S
Subjt:  GLYKIFDEILVNAADNKQRDPSMDSVKVNIDV---EQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFS

Query:  TEF-VIETADGKRMKKYKQKEVISISSTNCSV-----------------DFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTK
            VI   DG   ++ K      +++  C V                 D E+  + +   ++     ++  +F      +  K E       E D +++
Subjt:  TEF-VIETADGKRMKKYKQKEVISISSTNCSV-----------------DFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTK

Query:  VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIK---SFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVS
          +   L ++ ++ L  D     KK + D+ G      + E+NG  V +        Y D  L  A++ +T      HI+   +  +  TL+       S
Subjt:  VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIK---SFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVS

Query:  FVNGISTIKGGTHVDY----------ITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETL----------TKRPNSFGSACE
            +  IK   ++ Y           ++ +  + +  +N + K+ ++   +V+  L   ++  + NP F+ QTK  L                     E
Subjt:  FVNGISTIKGGTHVDY----------ITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETL----------TKRPNSFGSACE

Query:  LTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
        L P+ L+++ +KS  +++  + +  K++++L ++    K+  + G  KL D +      SE   + + EGDSA   A  G     R F  + PLRGK+LN
Subjt:  LTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN

Query:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMP
        +       + +N+EIQ +   LGL    E  N + LRY  ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K   R       Y   
Subjt:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMP

Query:  EYESWKESLRGNASGWSIKYYKGLG
          +    S  GNAS ++I+ +KGLG
Subjt:  EYESWKESLRGNASGWSIKYYKGLG

AT3G10690.1 DNA GYRASE A

9.7e-10

27.54

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Query:  LQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSE--HSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT
        L R++P V DGLKP  R+ILF   +     +    + +  V E     + HG+ ++  +++ MAQ F  S    L+  +G FG+ +      A+ RY   
Subjt:  LQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSE--HSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYT

Query:  KLSNVTR--FLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDII
        +L  +     L   D D +    N D    EP      +P +L+NG+ GI  G ++ +P +N  +++
Subjt:  KLSNVTR--FLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDII

AT3G23890.1 topoisomerase II

0.0e+00

61.06

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Query:  KRPLQNSNVTNVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSN  NV   PA  +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ LWVYE D MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNVTNVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADGKR+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VF +NMGKKSEP+ITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWV
        P+KSF DYVDLYL +A+  +TE P  R   K N+RWE+ V+LSEGQFQQVSFVN I+TIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWV
Subjt:  PIKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWV

Query:  FINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG
        F+NALIDNP+FDSQTKETLT R +SFGS CEL+ +FLK V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEG
Subjt:  FINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG

Query:  DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL
        DSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QIT NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL
Subjt:  DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL

Query:  KVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIED
        +VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WKESL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE 
Subjt:  KVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIED

Query:  RKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA
        RKNWL  + PG HLDQ    + YSDFVNKELILFSMADLQRSIPS+VDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMA
Subjt:  RKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA

Query:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI
        QD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I
Subjt:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI

Query:  IRNVRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHH
        + NVRR+L GE M+PMDPWYRGF GTIEKT++K+GG +YT++G+ EEV +TT+RI ELP+RRW +DYK+FL S+     K D         PF +    +
Subjt:  IRNVRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHH

Query:  SDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVN
        +D+K V  D+ L+EENML A QEG  KKFKLTTT++TSNMHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  +++N+E+ELLKLENK RFILAV++
Subjt:  SDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVN

Query:  GEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERV--------SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVD
        GEIIV+ R++ D+  +L+ KGFTPFP+K +SVE  +AGA +  D+A E PE +  +          S+Y+YLLA+AI +LTIEKV+EL  DRDK+   V 
Subjt:  GEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERV--------SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVD

Query:  DLRKATPKSLWLNDLDALEKELDEMDRNDAQAMEI--RKQQREKSNNDLKPKISRNAPKAP---RNSKKTINAETVTES---MDT---------------
        D++K TPKSLWL+DL++L+KEL+++D  DAQ  +     Q++ ++ +    K+ R APK P   + +KK   +ET   S   MDT               
Subjt:  DLRKATPKSLWLNDLDALEKELDEMDRNDAQAMEI--RKQQREKSNNDLKPKISRNAPKAP---RNSKKTINAETVTES---MDT---------------

Query:  -----TSSSTTEVANN---------PVVKPKGKAAPRKAPAKKGKAAVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRA
             + S TTE +++          VVKPKG+       AKK   A   + +EDE+L+L  RLA Y   S+P                           
Subjt:  -----TSSSTTEVANN---------PVVKPKGKAAPRKAPAKKGKAAVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRA

Query:  APKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAAAANAKTTKPPAAGVKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPFNKKSGS
        A   KT   S  I++ +DDDD+ + EVAP   KK     GGRK AA   K  KPPAA  K G++ +  T++L      G+SPEKKVRK+R+SPFNKKS S
Subjt:  APKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAAAANAKTTKPPAAGVKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPFNKKSGS

Query:  ILGRTIGEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED
        ++ R    +EEE  E  AGN           ++E+  G   A  R QRANR ++ YV+SDSESE+ + DS+FD+    DE+D
Subjt:  ILGRTIGEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED

AT3G23890.2 topoisomerase II

0.0e+00

62.19

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Query:  KRPLQNSNVTNVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSN  NV   PA  +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ LWVYE D MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNVTNVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADGKR+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VF +NMGKKSEP+ITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWV
        P+KSF DYVDLYL +A+  +TE P  R   K N+RWE+ V+LSEGQFQQVSFVN I+TIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWV
Subjt:  PIKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWV

Query:  FINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG
        F+NALIDNP+FDSQTKETLT R +SFGS CEL+ +FLK V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEG
Subjt:  FINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG

Query:  DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL
        DSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QIT NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL
Subjt:  DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL

Query:  KVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIED
        +VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WKESL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE 
Subjt:  KVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIED

Query:  RKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA
        RKNWL  + PG HLDQ    + YSDFVNKELILFSMADLQRSIPS+VDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMA
Subjt:  RKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA

Query:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI
        QD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I
Subjt:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI

Query:  IRNVRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHH
        + NVRR+L GE M+PMDPWYRGF GTIEKT++K+GG +YT++G+ EEV +TT+RI ELP+RRW +DYK+FL S+     K D         PF +    +
Subjt:  IRNVRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHH

Query:  SDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVN
        +D+K V  D+ L+EENML A QEG  KKFKLTTT++TSNMHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  +++N+E+ELLKLENK RFILAV++
Subjt:  SDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVN

Query:  GEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERV--------SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVD
        GEIIV+ R++ D+  +L+ KGFTPFP+K +SVE  +AGA +  D+A E PE +  +          S+Y+YLLA+AI +LTIEKV+EL  DRDK+   V 
Subjt:  GEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERV--------SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVD

Query:  DLRKATPKSLWLNDLDALEKELDEMDRNDAQAMEI--RKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSS-STTEVANN--PVVKPKG
        D++K TPKSLWL+DL++L+KEL+++D  DAQ  +     Q++ ++ +    K+ R APK P   K T  A   +ES  T +S S  +  NN   VVKPKG
Subjt:  DLRKATPKSLWLNDLDALEKELDEMDRNDAQAMEI--RKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSS-STTEVANN--PVVKPKG

Query:  KAAPRKAPAKKGKAAVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAA
        +       AKK   A   + +EDE+L+L  RLA Y   S+P                           A   KT   S  I++ +DDDD+ + EVAP   
Subjt:  KAAPRKAPAKKGKAAVLDDDDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAA

Query:  KKGGGRGGGRKAAAANAKTTKPPAAGVKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSET
        KK     GGRK AA   K  KPPAA  K G++ +  T++L      G+SPEKKVRK+R+SPFNKKS S++ R    +EEE  E  AGN           +
Subjt:  KKGGGRGGGRKAAAANAKTTKPPAAGVKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSET

Query:  TEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED
        +E+  G   A  R QRANR ++ YV+SDSESE+ + DS+FD+    DE+D
Subjt:  TEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED

AT5G04130.1 DNA GYRASE B2

6.5e-22

27.41

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Query:  VSFVNGISTIKGGTHVDYITNQIANYVMTVVNK----KNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETL----------TKRPNSFGSACELTPE
        + + N I TI GGTH++ +   +   + T+  K    K K+ ++   +V+  L   ++  + NP F+ QTK  L                     EL P+
Subjt:  VSFVNGISTIKGGTHVDYITNQIANYVMTVVNK----KNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETL----------TKRPNSFGSACELTPE

Query:  FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
         L+++ +KS  +++  + +  K++++L ++    K+  + G  KL D +    + SE   + + EGDSA   A  G     R F  + PLRGK+LN+   
Subjt:  FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA

Query:  SSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES
            + +N+EIQ +   LGL    E    + LRY  ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K   R       Y   + + 
Subjt:  SSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES

Query:  WKESLRGNASGWSIKYYKGLG
           +   NAS ++I+ +KGLG
Subjt:  WKESLRGNASGWSIKYYKGLG

Sequences

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CDS sequence

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ATGGCTGTCGAGAAGAAACGCCCACTGCAGAACAGCAACGTCACCAATGTCGACTCCAATCCGGCAGGTCCAAAGAAAACAATCGAAGAGATGTACCAGAAGAAGTCTCA
GCTCGAGCACATTCTCCTCAGACCCGATACCTATGTCGGATCTATTGAAAAGCACACCCAAAACCTCTGGGTTTACGAGAACGACAGAATGGTTCACCGATCCATCTCCT
ACGTGCCTGGTCTTTACAAGATCTTTGATGAAATTTTGGTCAATGCTGCAGATAATAAGCAGAGAGACCCTTCGATGGATTCAGTCAAGGTAAATATTGACGTCGAACAG
AACTGTATCAGCGTGTTCAACAATGGAGATGGAGTTCCGGTTGAAATTCATCAGGAAGAGAAGGTTTATGTGCCTGAGTTGATCTTTGGACATCTCTTGACTAGTAGTAA
CTATGATGATACTGAAAAGAAAACCACTGGTGGGCGCAATGGCTATGGTGCGAAACTTACCAATATTTTTTCCACTGAATTTGTGATCGAGACGGCTGATGGAAAACGCA
TGAAGAAGTATAAGCAGAAGGAAGTGATTAGCATCTCTTCGACTAATTGTTCGGTGGACTTTGAACTGATTTTATCTTGTATGTTTGATTCATACTCTTTTGCTGAGCCT
CATTTGAAAAATTACTCTTTCGATGTTTTCAATGATAACATGGGGAAAAAATCTGAGCCGATTATAACAAAGTGCAAGGAGGGTGATAATTGGACCAAGGTAACTTTTAA
GCCAGACTTGGCAAAGTTCAACATGACTCATCTTGAAGATGATGTTGTTGCCCTGATGAAAAAGAGAGTGTTGGATTTGGCCGGATGTCTTGGTAAAACCGTGAAGGTTG
AGCTGAATGGACAAAGGGTCCCTATTAAATCATTTCAAGATTATGTAGATCTTTACCTCAAATCAGCATCCACATTTCAGACGGAACCTCCGAAAAGGTATCACATTAAG
CCTAACGAGAGATGGGAAATTGTGGTGACCTTAAGTGAGGGCCAGTTCCAGCAGGTCAGCTTTGTGAACGGGATTTCAACTATTAAGGGTGGGACTCATGTTGATTACAT
CACTAATCAAATAGCAAATTATGTGATGACTGTTGTAAATAAGAAGAACAAAAATGCTAACGTGAAGGCCCACAATGTGAAGAGTTATTTATGGGTTTTTATCAACGCTC
TCATTGATAATCCATCCTTCGACTCCCAAACTAAGGAAACTTTGACAAAACGTCCAAACAGTTTTGGTTCTGCATGCGAACTTACGCCAGAGTTTTTGAAGAATGTGGCC
ACGAAATCTGGAATTATGGACAGCGTTCTCTCATGGGTTAATTTCAAGCAAAGCAAAGACCTGAAGAAAACAGATGGAGCAAAAACAGAAAAGATTAGTGGTATAGAAAA
GTTGGAGGATGCAAATTGCGCTGGAGGGAAGAACTCGGAAAAATGTACCTTAATTTTGACGGAAGGAGATTCAGCTAAGGCCCTTGCAATGGCTGGGCTTGGTGTAGTAG
GACGAGATTTTTATGGTGTATTCCCACTAAGAGGTAAATTGCTAAATGTGAGGGAAGCAAGTAGTAAACAGATCACAGAGAATAAAGAAATTCAATACATCAAACAAATT
CTTGGACTTCAGCAAGGGAAGGAATACAGCAATGCTAAGGCTTTGAGATATGGTCATTTGATGATTATGACCGATCAGGATCATGATGGTTCACACATTAAAGGACTTTT
GATCAATTTTATTCATTCTTTCTGGCCTTCTCTCCTAAAAGTGCCGTCGTTCTTGGTTGAATTCATAACGCCTATTGTCAAGGCTACTCATAGGAATGGAACTGTTTTGT
CATTCTATACCATGCCCGAGTACGAGTCTTGGAAAGAGAGCTTGAGAGGCAATGCAAGTGGCTGGTCAATCAAGTACTATAAGGGGTTGGGAACGAGCACATCAAAAGAA
GGAAGAGAGTACTTTGAACAGCTGACAAAGCACAAGAAAGATTTTATTTGGCAAGATGATAATGATGGGGAGGCCATTGAGCTTGCTTTCAGTAAGAAGAAGATTGAAGA
TAGAAAGAACTGGCTCCGTCAATTTGAGCCTGGTACCCATCTAGATCAGACAGGAAAATTGATAAAGTACAGTGACTTCGTCAACAAGGAGCTTATATTATTTTCAATGG
CTGATTTACAAAGGTCTATTCCCTCAGTGGTTGATGGCCTTAAGCCTGGCCAAAGGAAGATCCTTTTCTGTTCTTTCAAGAGGAACTTTGTCAAAGAAGCAAAGGTTTCT
CAATTTTCCGGTTATGTATCTGAGCACTCTGCATATCATCATGGTGAGCAGAGTCTTGCTAGTACCATCATTGGAATGGCACAGGACTTCGTTGGCAGCAACAACATTAA
TCTTCTTCTACCAAATGGACAGTTTGGCACACGGAACCATGGAGGCAAAGATCATGCAAGTTCTAGGTACATTTACACTAAACTTTCAAATGTCACACGGTTCCTTTTCC
CAAAAGACGACGACAAACTTCTTAACTACTTAAATGAAGACGGCCAGTCGATTGAACCAACCTGGTATATGCCTATCATACCAACTGTTCTTGTCAATGGAAGTGAAGGA
ATTGGAACCGGGTGGAGTTCGTACGTTCCAAATTATAATCCTAGAGACATCATTAGAAACGTAAGACGTATGTTGGAAGGTGAAATGATGTTGCCAATGGATCCCTGGTA
TAGAGGTTTTTCAGGAACTATAGAGAAAACTTCCACTAAAGACGGAGGCACTAGTTACACTGTTAGTGGAATTATAGAGGAAGTCAGTGATACGACGTTGAGAATAATTG
AATTGCCAGTCCGCCGATGGACTAATGACTACAAGGACTTTCTGGACTCTGTCACAAGAGTTGCAACAAAGCATGACAAAGATAAAGAAAAAGCAGCGAAGGATCCTTTT
ATTGAGCAAGCTGATCACCACAGCGATGACAAAATTGTTTCCATTGATGTTCACTTAACGGAGGAAAACATGTTATTGGCCATCCAAGAAGGTTTGAAGAAGAAATTCAA
ATTAACTACAACTGTCAGCACTAGCAACATGCACTTGTTTGATGCAAATGGCGTGATTAAGAAATATGACACCCCAGAACAAATTCTTGAGGAATTTTTTCCCCTGAGAC
TTGAATTCTACGAGAAAAGAAAGAGGAATCTTTTGGAAAACCTTGAAATGGAGTTGCTTAAACTGGAAAACAAGGTGAGGTTTATCCTTGCTGTTGTGAATGGAGAGATA
ATAGTAAGCAATAGAAGAAGGGTTGATTTGTTCCATGAGCTTCAAGCGAAAGGCTTTACACCCTTTCCGAAGAAGACTAAATCTGTTGAGCCAGAAGTTGCTGGGGCATC
TAATGAAACAGATGAAGCAGAGGAGAGTCCGGAAGCAGTAAAAGGCGAAAGAGTTAGTGATTACGAGTATTTACTAGCCCTGGCAATTGGAACCTTGACCATTGAGAAGG
TTCAGGAGCTATGTAATGATAGAGACAAGTTGAAAGGGGAAGTGGACGATCTGAGGAAGGCAACCCCCAAGTCTTTGTGGCTGAATGACCTTGATGCTCTTGAGAAAGAA
CTTGATGAGATGGATAGAAATGATGCTCAGGCAATGGAGATAAGAAAACAGCAGAGAGAAAAATCAAATAACGATTTAAAGCCAAAAATCTCTAGAAATGCTCCAAAAGC
TCCACGTAACAGTAAGAAAACCATCAATGCAGAAACTGTCACGGAAAGTATGGACACAACATCTAGTTCTACAACGGAAGTTGCAAATAATCCGGTGGTGAAGCCCAAAG
GCAAAGCAGCTCCAAGAAAAGCTCCCGCTAAGAAGGGTAAAGCTGCAGTTCTTGATGACGACGACGAAGACGAAATCCTCGAGCTTAAAGACCGTCTTGCTGCCTACAAA
ATTGAGTCATCTCCTGAACCATCAGAAGTTTCAGCCATGGAAACTGAAGTGCCGCAAGTACAAGCGGCCAAGAAGAAAGAACCCAGCAAGAGAGCAGCTCCCAAGAAGAA
AACTACTGCAAAGTCTGCTCAGATCTCCATTAGCGAGGACGATGACGACTTGGAAATAAAGGAGGTAGCCCCTCCGGCAGCCAAGAAGGGAGGAGGAAGAGGAGGAGGAA
GAAAGGCGGCTGCTGCAAATGCCAAAACAACCAAGCCCCCTGCTGCAGGAGTGAAGTTGGGACAGAAACTGATAACTCAAATGCTGGAACCAGCAGAGAACTCCGGCATC
TCACCGGAGAAGAAAGTGAGGAAGATAAGAGCATCACCTTTCAATAAGAAAAGTGGCTCTATATTGGGAAGAACAATTGGGGAAGAGGAAGAAGAAGAAGAAGAAGAAGA
AGCTGGAAATGAAGAGAAGTTGATGGGTTCTGCTTCTTCTGAGACCACTGAAGAAGTTGCCGGATTTCGGCCGGCGAGAGGAAGATCACAGAGAGCAAACAGAACACAGG
TGAAATATGTGGTTAGTGATTCAGAGAGTGAGGCAGTTTCTGAGGATTCGGACTTTGATGAAGAAGCCAGCCTTGATGAAGAAGATTGA

mRNA sequence

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Protein sequence

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MAVEKKRPLQNSNVTNVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQ
NCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNCSVDFELILSCMFDSYSFAEP
HLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIKSFQDYVDLYLKSASTFQTEPPKRYHIK
PNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVA
TKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQI
LGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKE
GREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSVVDGLKPGQRKILFCSFKRNFVKEAKVS
QFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEG
IGTGWSSYVPNYNPRDIIRNVRRMLEGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPF
IEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPEAVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDALEKE
LDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKAAVLDDDDEDEILELKDRLAAYK
IESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAAAANAKTTKPPAAGVKLGQKLITQMLEPAENSGI
SPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED

CaUC10G192430 (gene) of Watermelon (USVL246-FR2) v1 genome