CuGenDBv2

Gene ID	Carg00490
Organism	Cucurbita argyrosperma subsp. argyrosperma cv. SMH-JMG-627 (Silver-seed gourd (SMH-JMG-627) v2)
Description	alkaline ceramidase
Genome location	Carg_Chr03:5295909..5296375
RNA-Seq Expression	Carg00490
Synteny	Carg00490
Gene Ontology terms	GO:0006665 - sphingolipid metabolic process (biological process) GO:0006914 - autophagy (biological process) GO:0009651 - response to salt stress (biological process) GO:0098542 - defense response to other organism (biological process) GO:0110165 - cellular anatomical structure (cellular component)
InterPro domains	IPR044219 - Alkaline ceramidase, plant

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6603812.1 Alkaline ceramidase, partial [Cucurbita argyrosperma subsp. sororia]

4.9e-50

99.03

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Query:  MILAIGSMFFHATLQKVWFLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAKRLAKLYSSTFLLGIFCWVIDRGTARRYQIGSS
        MILAIGSMFFHATLQKV FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAKRLAKLYSSTFLLGIFCWVIDRGTARRYQIGSS
Subjt:  MILAIGSMFFHATLQKVWFLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAKRLAKLYSSTFLLGIFCWVIDRGTARRYQIGSS

Query:  ILK
        ILK
Subjt:  ILK

KAG7033992.1 Alkaline ceramidase, partial [Cucurbita argyrosperma subsp. argyrosperma]

8.9e-68

100

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Query:  MILAIGSMFFHATLQKVWFLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAKRLAKLYSSTFLLGIFCWVIDRGTARRYQIGSS
        MILAIGSMFFHATLQKVWFLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAKRLAKLYSSTFLLGIFCWVIDRGTARRYQIGSS
Subjt:  MILAIGSMFFHATLQKVWFLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAKRLAKLYSSTFLLGIFCWVIDRGTARRYQIGSS

Query:  ILKQRGWAPQVLHLMGILPSVKIEKPKTQ
        ILKQRGWAPQVLHLMGILPSVKIEKPKTQ
Subjt:  ILKQRGWAPQVLHLMGILPSVKIEKPKTQ

XP_008440061.1 PREDICTED: alkaline ceramidase 3 [Cucumis melo]

1.7e-39

52.94

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Query:  MILAIGSMFFHATLQKV------------------------W--------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK
        MILAIGSMF+HATLQKV                        W        FLF YG MFAVAHSILRYDIGFKVHYV LCLLC+PRMYKYY+ T+D SAK
Subjt:  MILAIGSMFFHATLQKV------------------------W--------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK

Query:  RLAKLYSSTFLLGIFCWVIDRGTARR----------------------YQIGSSIL----KQRGWAPQVLHLMGILPSVKIEKPKTQ
        RLA+LYS T LLG FCWV DRG   +                      Y   + ++    +QRGW+P+VLHLMG+LP VKIEKPKTQ
Subjt:  RLAKLYSSTFLLGIFCWVIDRGTARR----------------------YQIGSSIL----KQRGWAPQVLHLMGILPSVKIEKPKTQ

XP_023003815.1 alkaline ceramidase [Cucurbita maxima]

2.3e-39

53.48

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Query:  MILAIGSMFFHATLQKV------------------------W--------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK
        MILAIGSMF+HATLQKV                        W        FLF YG +FAVAHSILRYDIGFK+HYV LCLLC+PRMYKYY+ T+D SAK
Subjt:  MILAIGSMFFHATLQKV------------------------W--------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK

Query:  RLAKLYSSTFLLGIFCWVIDRGTARR----------------------YQIGSSIL----KQRGWAPQVLHLMGILPSVKIEKPKTQ
        RLA+LY  T LLGIFCWVIDRG   +                      Y   + ++    +QRGWAP+VLHLMGILP VKIEKPKTQ
Subjt:  RLAKLYSSTFLLGIFCWVIDRGTARR----------------------YQIGSSIL----KQRGWAPQVLHLMGILPSVKIEKPKTQ

XP_038882449.1 alkaline ceramidase [Benincasa hispida]

7.8e-40

53.48

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Query:  MILAIGSMFFHATLQKV------------------------W--------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK
        MILAIGSMF+HATLQKV                        W        FLF YG MFAVAHSILRYDIGFKVHYV LCLLC+PRMYKYY+ T+D SAK
Subjt:  MILAIGSMFFHATLQKV------------------------W--------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK

Query:  RLAKLYSSTFLLGIFCWVIDRGTARR----------------------YQIGSSIL----KQRGWAPQVLHLMGILPSVKIEKPKTQ
        RLA+LYS T LLGIFCWV+D+G   +                      Y   + ++    +QRGWAP+VLHLMG+LP VKIEKPKTQ
Subjt:  RLAKLYSSTFLLGIFCWVIDRGTARR----------------------YQIGSSIL----KQRGWAPQVLHLMGILPSVKIEKPKTQ

TrEMBL top hits

e value

%identity

Alignment

A0A1S3B0Z4 alkaline ceramidase 3

8.5e-40

52.94

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Query:  MILAIGSMFFHATLQKV------------------------W--------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK
        MILAIGSMF+HATLQKV                        W        FLF YG MFAVAHSILRYDIGFKVHYV LCLLC+PRMYKYY+ T+D SAK
Subjt:  MILAIGSMFFHATLQKV------------------------W--------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK

Query:  RLAKLYSSTFLLGIFCWVIDRGTARR----------------------YQIGSSIL----KQRGWAPQVLHLMGILPSVKIEKPKTQ
        RLA+LYS T LLG FCWV DRG   +                      Y   + ++    +QRGW+P+VLHLMG+LP VKIEKPKTQ
Subjt:  RLAKLYSSTFLLGIFCWVIDRGTARR----------------------YQIGSSIL----KQRGWAPQVLHLMGILPSVKIEKPKTQ

A0A5D3CM37 Alkaline ceramidase 3

5.7e-36

59.85

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Query:  FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAKRLAKLYSSTFLLGIFCWVIDRGTARR----------------------YQ
        FLF YG MFAVAHSILRYDIGFKVHYV LCLLC+PRMYKYY+ T+D SAKRLA+LYS T LLG FCWV DRG   +                      Y 
Subjt:  FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAKRLAKLYSSTFLLGIFCWVIDRGTARR----------------------YQ

Query:  IGSSIL----KQRGWAPQVLHLMGILPSVKIEKPKTQ
          + ++    +QRGW+P+VLHLMG+LP VKIEKPKTQ
Subjt:  IGSSIL----KQRGWAPQVLHLMGILPSVKIEKPKTQ

A0A6J1BUA9 alkaline ceramidase

3.6e-38

52.41

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Query:  MILAIGSMFFHATLQK----------VW----------------------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK
        MILAIGSMF+HATLQK          +W                      FLF YG +FAVAHSILRY IGFKVHYV LCLLC+PRMYKYY+ T+D SAK
Subjt:  MILAIGSMFFHATLQK----------VW----------------------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK

Query:  RLAKLYSSTFLLGIFCWVIDRGTARRYQ-----------------IGSSI---------LKQRGWAPQVLHLMGILPSVKIEKPKTQ
        RLA+LY  T  LGI CWVIDRG   +                   +GS            +QRGWAP+VLHLMGILP VKIEKPKTQ
Subjt:  RLAKLYSSTFLLGIFCWVIDRGTARRYQ-----------------IGSSI---------LKQRGWAPQVLHLMGILPSVKIEKPKTQ

A0A6J1EME1 alkaline ceramidase

9.3e-39

52.94

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Query:  MILAIGSMFFHATLQKV------------------------W--------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK
        MILAIGSMF+HATLQKV                        W        FLF YG +FAVAHSILRYDIGFK+HYV LCLLC+PRMYKYY+ T+D SAK
Subjt:  MILAIGSMFFHATLQKV------------------------W--------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK

Query:  RLAKLYSSTFLLGIFCWVIDRGTARR----------------------YQIGSSIL----KQRGWAPQVLHLMGILPSVKIEKPKTQ
        RLA+LY  T LLGIFCWVIDR    +                      Y   + ++    +QRGWAP+VLHLMGILP VKIEKPKTQ
Subjt:  RLAKLYSSTFLLGIFCWVIDRGTARR----------------------YQIGSSIL----KQRGWAPQVLHLMGILPSVKIEKPKTQ

A0A6J1KSV2 alkaline ceramidase

1.1e-39

53.48

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Query:  MILAIGSMFFHATLQKV------------------------W--------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK
        MILAIGSMF+HATLQKV                        W        FLF YG +FAVAHSILRYDIGFK+HYV LCLLC+PRMYKYY+ T+D SAK
Subjt:  MILAIGSMFFHATLQKV------------------------W--------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK

Query:  RLAKLYSSTFLLGIFCWVIDRGTARR----------------------YQIGSSIL----KQRGWAPQVLHLMGILPSVKIEKPKTQ
        RLA+LY  T LLGIFCWVIDRG   +                      Y   + ++    +QRGWAP+VLHLMGILP VKIEKPKTQ
Subjt:  RLAKLYSSTFLLGIFCWVIDRGTARR----------------------YQIGSSIL----KQRGWAPQVLHLMGILPSVKIEKPKTQ

SwissProt top hits

e value

%identity

Alignment

Q94IB9 Alkaline ceramidase

5.3e-31

43.32

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Query:  MILAIGSMFFHATLQKV------------------------W--------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK
        MILAIGSM +HATLQ V                        W        FLF YG  FA+ H+ LR+ IGFKVHYV LCLLC+PRMYKYY+ T+DT+AK
Subjt:  MILAIGSMFFHATLQKV------------------------W--------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK

Query:  RLAKLYSSTFLLGIFCWVIDR---GTARRYQI---GSSI--------------------LKQRGWAPQVLHLMGILPSVKIEKPKTQ
        R+AK Y +T L+G  CW  DR    T  ++ +   G ++                     +QRGW P+V + +G+LP VKIEKPKTQ
Subjt:  RLAKLYSSTFLLGIFCWVIDR---GTARRYQI---GSSI--------------------LKQRGWAPQVLHLMGILPSVKIEKPKTQ

Arabidopsis top hits

e value

%identity

Alignment

AT4G22330.1 Alkaline phytoceramidase (aPHC)

3.8e-32

43.32

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Query:  MILAIGSMFFHATLQKV------------------------W--------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK
        MILAIGSM +HATLQ V                        W        FLF YG  FA+ H+ LR+ IGFKVHYV LCLLC+PRMYKYY+ T+DT+AK
Subjt:  MILAIGSMFFHATLQKV------------------------W--------FLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAK

Query:  RLAKLYSSTFLLGIFCWVIDR---GTARRYQI---GSSI--------------------LKQRGWAPQVLHLMGILPSVKIEKPKTQ
        R+AK Y +T L+G  CW  DR    T  ++ +   G ++                     +QRGW P+V + +G+LP VKIEKPKTQ
Subjt:  RLAKLYSSTFLLGIFCWVIDR---GTARRYQI---GSSI--------------------LKQRGWAPQVLHLMGILPSVKIEKPKTQ

Sequences

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CDS sequence

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ATGATACTGGCCATTGGCAGTATGTTCTTCCATGCCACATTGCAAAAAGTTTGGTTCCTCTTCCCCTATGGAGTCATGTTCGCCGTGGCTCACTCGATTCTTCGTTATGA
CATTGGTTTCAAGGTGCACTATGTGAATCTTTGCCTCCTCTGCGTACCTCGGATGTACAAGTATTATATGTGCACACAAGATACCTCGGCTAAGCGGTTAGCAAAGCTGT
ACTCGTCGACGTTTCTCTTAGGCATTTTCTGTTGGGTCATCGATCGGGGTACTGCAAGAAGATATCAGATTGGATCATCAATCCTTAAGCAAAGAGGATGGGCCCCTCAA
GTTCTTCATTTAATGGGAATTCTCCCCTCCGTGAAGATTGAGAAACCAAAAACCCAGTAA

mRNA sequence

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Protein sequence

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MILAIGSMFFHATLQKVWFLFPYGVMFAVAHSILRYDIGFKVHYVNLCLLCVPRMYKYYMCTQDTSAKRLAKLYSSTFLLGIFCWVIDRGTARRYQIGSSILKQRGWAPQ
VLHLMGILPSVKIEKPKTQ

Carg00490 (gene) of Silver-seed gourd (SMH-JMG-627) v2 genome