CuGenDBv2

Gene ID	Carg05551
Organism	Cucurbita argyrosperma subsp. argyrosperma cv. SMH-JMG-627 (Silver-seed gourd (SMH-JMG-627) v2)
Description	HYPK_UBA domain-containing protein
Genome location	Carg_Chr17:2162391..2164816
RNA-Seq Expression	Carg05551
Synteny	Carg05551
Gene Ontology terms	GO:0043066 - negative regulation of apoptotic process (biological process) GO:0050821 - protein stabilization (biological process) GO:0110165 - cellular anatomical structure (cellular component)
InterPro domains	IPR038922 - Huntingtin-interacting protein K, UBA-like domain IPR044034 - Nascent polypeptide-associated complex subunit alpha-like, UBA domain

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6575116.1 Huntingtin-interacting protein K, partial [Cucurbita argyrosperma subsp. sororia]

3.0e-48

100

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Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLLR
        AVAAIRYLLR
Subjt:  AVAAIRYLLR

XP_004148802.1 huntingtin-interacting protein K [Cucumis sativus]

1.5e-47

98.18

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Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDG+E LVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLLR
        AVAAIRYLLR
Subjt:  AVAAIRYLLR

XP_008458350.1 PREDICTED: huntingtin-interacting protein K [Cucumis melo]

4.3e-47

98.17

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Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDG+E LVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLL
        AVAAIRYLL
Subjt:  AVAAIRYLL

XP_022958793.1 huntingtin-interacting protein K [Cucurbita moschata]

3.0e-48

100

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Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLLR
        AVAAIRYLLR
Subjt:  AVAAIRYLLR

XP_038906945.1 huntingtin-interacting protein K [Benincasa hispida]

1.1e-47

99.09

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Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDGVE LVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLLR
        AVAAIRYLLR
Subjt:  AVAAIRYLLR

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KI65 HYPK_UBA domain-containing protein

7.2e-48

98.18

Show/hide

Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDG+E LVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLLR
        AVAAIRYLLR
Subjt:  AVAAIRYLLR

A0A1S3C895 huntingtin-interacting protein K

2.1e-47

98.17

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Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDG+E LVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLL
        AVAAIRYLL
Subjt:  AVAAIRYLL

A0A6J1CC39 huntingtin-interacting protein K

1.0e-46

97.25

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Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        ME GDDGVE LVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAAD+DIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLL
        AVAAIRYLL
Subjt:  AVAAIRYLL

A0A6J1H656 huntingtin-interacting protein K

1.4e-48

100

Show/hide

Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLLR
        AVAAIRYLLR
Subjt:  AVAAIRYLLR

A0A6J1L4Y3 huntingtin-interacting protein K

1.4e-48

100

Show/hide

Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLLR
        AVAAIRYLLR
Subjt:  AVAAIRYLLR

SwissProt top hits

e value

%identity

Alignment

Q2PFU1 Huntingtin-interacting protein K

5.4e-08

37.04

Show/hide

Query:  DKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAVAAI
        +++TD  E++++ S+ ++ AM+ I      +  A   REKELA V I   D+++I  E+E+ +  AER+LREH G+ V A+
Subjt:  DKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAVAAI

Q9CR41 Huntingtin-interacting protein K

5.4e-08

37.04

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Query:  DKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAVAAI
        +++TD  E++++ S+ ++ AM+ I      +  A   REKELA V I   D+++I  E+E+ +  AER+LREH G+ V A+
Subjt:  DKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAVAAI

Q9NX55 Huntingtin-interacting protein K

5.4e-08

37.04

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Query:  DKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAVAAI
        +++TD  E++++ S+ ++ AM+ I      +  A   REKELA V I   D+++I  E+E+ +  AER+LREH G+ V A+
Subjt:  DKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAVAAI

Arabidopsis top hits

e value

%identity

Alignment

AT3G06610.1 DNA-binding enhancer protein-related

1.3e-36

78.5

Show/hide

Query:  AGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAV
        A + G E  VDSKD+QQQSKAFDKLTDRVEDRQLDS+RVQ AMASIAAS EAD NA  LREKELA+VKIN ADV+ I NELE++K VAERTLREHKGDAV
Subjt:  AGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAV

Query:  AAIRYLL
        AA R LL
Subjt:  AAIRYLL

Sequences

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CDS sequence

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ATGGAAGCGGGAGACGATGGAGTCGAGAGTCTGGTAGATTCGAAGGATATGCAGCAACAGAGCAAAGCCTTCGATAAGCTCACTGATCGTGTTGAAGACCGGCAACTCGA
TTCCACTCGTGTTCAAGAGGCAATGGCATCTATTGCTGCATCGGCCGAAGCCGATTGGAACGCGATGATGTTGAGAGAGAAGGAGCTCGCTGCTGTCAAAATAAACGCAG
CTGACGTCGACATAATCGCCAACGAACTCGAGTTGGACAAGAAGGTTGCCGAGAGAACCTTGCGAGAGCACAAAGGCGACGCGGTTGCTGCTATACGGTATTTACTACGC
TGA

mRNA sequence

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ATAGTCGACGAGTTGGAAATTGTTACCGAGGGTTCGCTGTTCTTAGCTCCTTGCCGTCGCCGATTTGTTACGATTCTCAGTTGCAGCAGGTTCTTCGATTGTTGCTAAAA
ATCACAGAAAATACTGCTACGTTGTGAGTTTGAGAATTCACAGAAAATGGAAGCGGGAGACGATGGAGTCGAGAGTCTGGTAGATTCGAAGGATATGCAGCAACAGAGCA
AAGCCTTCGATAAGCTCACTGATCGTGTTGAAGACCGGCAACTCGATTCCACTCGTGTTCAAGAGGCAATGGCATCTATTGCTGCATCGGCCGAAGCCGATTGGAACGCG
ATGATGTTGAGAGAGAAGGAGCTCGCTGCTGTCAAAATAAACGCAGCTGACGTCGACATAATCGCCAACGAACTCGAGTTGGACAAGAAGGTTGCCGAGAGAACCTTGCG
AGAGCACAAAGGCGACGCGGTTGCTGCTATACGGTATTTACTACGCTGATTCATCAGGTGTTTGAAGAGACTCTGTTTACTTATTACTTGAAGTTTTACTGGGAAAACTA
ATCTGAAGTGCACAAGTGAGAATCATAAACATACTTTTTGTGAGTTCAGATTGTATGGAAATGCTGGAAGTTTCTTCTTTTTCCTTCTTTGTAAACCTTAAAATATTAGT
TCTAAATCTCTTTGCTGAAGGGGGATTCGATGAAAGTGGCCATGTCTTTAAAGCCCATTTGATGATACCCAGATAATCTGTGGTTGGTTGGGTTGGTGTTTAAAAAGGTT
TCAATACGTTCACGGGATTTATGCACATACCCCATAAATGGTTCCTTCCGAGGTGGAAAAGACTGAAAAGAATCGATGAAACCCGAGTTTAGCCTAATTCATAGGGTCAT
ATTTGTAATTTTGTTTCTTTGAAACTTATGTCTATTTGGTCTAAAATCTGTGATACAACTCCATGTTACTAAATTGACATGGAATAAAGCCAAAGCATTATAGTTTGAAT
AGTTTATAACTAGGCATGGTATGGAATTACATGAAATCATAAGAACTCGAAGAGCACCTAGTGGGAGCT

Protein sequence

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MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAVAAIRYLLR

Carg05551 (gene) of Silver-seed gourd (SMH-JMG-627) v2 genome