CuGenDBv2

Gene ID	Carg14259
Organism	Cucurbita argyrosperma subsp. argyrosperma cv. SMH-JMG-627 (Silver-seed gourd (SMH-JMG-627) v2)
Description	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
Genome location	Carg_Chr04:4679590..4679883
RNA-Seq Expression	Carg14259
Synteny	Carg14259
Gene Ontology terms	GO:0030148 - sphingolipid biosynthetic process (biological process) GO:0030497 - fatty acid elongation (biological process) GO:0042761 - very long-chain fatty acid biosynthetic process (biological process) GO:0030176 - integral component of endoplasmic reticulum membrane (cellular component) GO:0018812 - 3-hydroxyacyl-CoA dehydratase activity (molecular function) GO:0102158 - very-long-chain 3-hydroxyacyl-CoA dehydratase activity (molecular function) GO:0102343 - 3-hydroxy-arachidoyl-CoA dehydratase activity (molecular function) GO:0102344 - 3-hydroxy-behenoyl-CoA dehydratase activity (molecular function) GO:0102345 - 3-hydroxy-lignoceroyl-CoA dehydratase activity (molecular function)
InterPro domains	IPR007482 - Protein-tyrosine phosphatase-like, PTPLA

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6600692.1 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PASTICCINO 2, partial [Cucurbita argyrosperma subsp. sororia]

2.3e-25

98.39

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Query:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV
        MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLE+
Subjt:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV

KAG7031326.1 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PASTICCINO 2, partial [Cucurbita argyrosperma subsp. argyrosperma]

5.6e-32

100

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Query:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEVFPDRFWFMS
        MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEVFPDRFWFMS
Subjt:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEVFPDRFWFMS

XP_022942204.1 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PASTICCINO 2A-like isoform X2 [Cucurbita moschata]

2.3e-25

98.39

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Query:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV
        MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLE+
Subjt:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV

XP_022942935.1 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PASTICCINO 2A-like isoform X2 [Cucurbita moschata]

2.3e-25

98.39

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Query:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV
        MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLE+
Subjt:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV

XP_022975564.1 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PASTICCINO 2A isoform X2 [Cucurbita maxima]

2.3e-25

98.39

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Query:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV
        MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLE+
Subjt:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV

TrEMBL top hits

e value

%identity

Alignment

A0A0A0L3F8 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase

2.6e-22

83.87

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Query:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV
        MAGFL+T+RRLYL++YNWTLF GWVQVFYF +KQLKESGHQ VYNAVERPLQF+QTAAVLE+
Subjt:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV

A0A1S3BT98 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase

4.0e-23

87.1

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Query:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV
        MAGFL+T+RRLYL+IYNWTLF GWVQVFYF +KQLKESGHQQVYNAVERPLQF+QTAAVLE+
Subjt:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV

A0A6J1FQM5 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase

1.1e-25

98.39

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Query:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV
        MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLE+
Subjt:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV

A0A6J1FX62 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase

1.1e-25

98.39

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Query:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV
        MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLE+
Subjt:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV

A0A6J1IKY7 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase

1.1e-25

98.39

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Query:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV
        MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLE+
Subjt:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV

SwissProt top hits

e value

%identity

Alignment

Q5ZEJ0 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PASTICCINO 2B

9.1e-17

64.52

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Query:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV
        M G  + +RRLYLS+YNW +F GW QV Y++V  L ESGH+ VY AVERPLQFAQTAA LE+
Subjt:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV

Q7XSZ4 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PASTICCINO 2A

3.1e-17

66.13

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Query:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV
        MAG  + +RRLYLS+YNW +F GW QV Y++V  L ESGH+ VY AVERPLQFAQTAA LE+
Subjt:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV

Q8VZB2 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase PASTICCINO 2

2.4e-17

59.68

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Query:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV
        MAGFL+ +RR+YL++YNW +F GW QV Y ++  LKE+G++ VY+A+E+PLQ AQTAAVLE+
Subjt:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV

Arabidopsis top hits

e value

%identity

Alignment

AT5G10480.1 Protein-tyrosine phosphatase-like, PTPLA

1.7e-18

59.68

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Query:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV
        MAGFL+ +RR+YL++YNW +F GW QV Y ++  LKE+G++ VY+A+E+PLQ AQTAAVLE+
Subjt:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV

AT5G10480.2 Protein-tyrosine phosphatase-like, PTPLA

8.8e-07

58.33

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Query:  VFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV
        V Y ++  LKE+G++ VY+A+E+PLQ AQTAAVLE+
Subjt:  VFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV

AT5G10480.3 Protein-tyrosine phosphatase-like, PTPLA

1.7e-18

59.68

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Query:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV
        MAGFL+ +RR+YL++YNW +F GW QV Y ++  LKE+G++ VY+A+E+PLQ AQTAAVLE+
Subjt:  MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEV

Sequences

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CDS sequence

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ATGGCGGGATTTTTGGCAACTATTCGGCGCCTGTACCTCTCCATCTACAATTGGACTCTCTTCGTCGGATGGGTTCAGGTGTTCTACTTCTCAGTCAAGCAATTGAAGGA
ATCTGGTCACCAACAGGTATATAATGCCGTCGAACGTCCTCTTCAGTTTGCTCAAACTGCAGCTGTTTTAGAGGTATTCCCTGATCGTTTCTGGTTTATGAGCTGA

mRNA sequence

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Protein sequence

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MAGFLATIRRLYLSIYNWTLFVGWVQVFYFSVKQLKESGHQQVYNAVERPLQFAQTAAVLEVFPDRFWFMS

Carg14259 (gene) of Silver-seed gourd (SMH-JMG-627) v2 genome