CuGenDBv2

Gene ID	Carg17944
Organism	Cucurbita argyrosperma subsp. argyrosperma cv. SMH-JMG-627 (Silver-seed gourd (SMH-JMG-627) v2)
Description	dCTP pyrophosphatase 1
Genome location	Carg_Chr10:970411..971105
RNA-Seq Expression	Carg17944
Synteny	Carg17944
Gene Ontology terms	GO:0006253 - dCTP catabolic process (biological process) GO:0042262 - DNA protection (biological process) GO:0005829 - cytosol (cellular component) GO:0000287 - magnesium ion binding (molecular function) GO:0047840 - dCTP diphosphatase activity (molecular function)
InterPro domains	IPR025984 - dCTP pyrophosphatase 1

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6589527.1 dCTP pyrophosphatase 1, partial [Cucurbita argyrosperma subsp. sororia]

2.9e-63

100

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Query:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFARALP
        GHAALSKLVKNANKYPVAAFARALP
Subjt:  GHAALSKLVKNANKYPVAAFARALP

XP_004138182.1 dCTP pyrophosphatase 1 [Cucumis sativus]

2.1e-61

97.6

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Query:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEK AKDVSLQELRD LAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFARALP
        GHAALSKLVKNANKYPVAAF RALP
Subjt:  GHAALSKLVKNANKYPVAAFARALP

XP_022921755.1 dCTP pyrophosphatase 1-like [Cucurbita moschata]

1.4e-62

99.2

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Query:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEK AKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFARALP
        GHAALSKLVKNANKYPVAAFARALP
Subjt:  GHAALSKLVKNANKYPVAAFARALP

XP_022987438.1 dCTP pyrophosphatase 1-like [Cucurbita maxima]

5.4e-62

98.4

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Query:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEK AKDVSLQELRDML EFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFARALP
        GHAALSKLVKNANKYPVAAFARALP
Subjt:  GHAALSKLVKNANKYPVAAFARALP

XP_038880679.1 dCTP pyrophosphatase 1-like [Benincasa hispida]

1.0e-60

96.8

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Query:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        ME+ SYEPEK AKDVSLQELRD LAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFARALP
        GHAALSKLVKNANKYPVAAFARALP
Subjt:  GHAALSKLVKNANKYPVAAFARALP

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LP76 dCTP pyrophosphatase 1

9.9e-62

97.6

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Query:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEK AKDVSLQELRD LAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFARALP
        GHAALSKLVKNANKYPVAAF RALP
Subjt:  GHAALSKLVKNANKYPVAAFARALP

A0A1S3BWI5 dCTP pyrophosphatase 1

1.1e-60

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Query:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEK AKDVSLQELRD LAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFARALP
        GHAA+SKLVKNANKYPVAA  RALP
Subjt:  GHAALSKLVKNANKYPVAAFARALP

A0A5A7UWT3 dCTP pyrophosphatase 1

1.1e-60

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Query:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEK AKDVSLQELRD LAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFARALP
        GHAA+SKLVKNANKYPVAA  RALP
Subjt:  GHAALSKLVKNANKYPVAAFARALP

A0A6J1E6P9 dCTP pyrophosphatase 1

6.9e-63

99.2

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Query:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEK AKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFARALP
        GHAALSKLVKNANKYPVAAFARALP
Subjt:  GHAALSKLVKNANKYPVAAFARALP

A0A6J1JJF8 dCTP pyrophosphatase 1

2.6e-62

98.4

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Query:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
        MENRSYEPEK AKDVSLQELRDML EFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNANKYPVAAFARALP
        GHAALSKLVKNANKYPVAAFARALP
Subjt:  GHAALSKLVKNANKYPVAAFARALP

SwissProt top hits

e value

%identity

Alignment

Q32KY6 dCTP pyrophosphatase 1

1.0e-26

53.64

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Query:  PEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAALSK
        P   + + +L+++R + AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   WS  ER  L+EE+SD+L+YLV LA  C +DL  A L K
Subjt:  PEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAALSK

Query:  LVKNANKYPV
        +  N  +YPV
Subjt:  LVKNANKYPV

Q91VC0 dCTP pyrophosphatase 1

4.5e-27

53.98

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Query:  SYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAA
        S+ PE      +L+++R + AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   W   ER  L+EE+SDVL+YLV LA  C +DL  A 
Subjt:  SYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAA

Query:  LSKLVKNANKYPV
        +SK+  N  +YPV
Subjt:  LSKLVKNANKYPV

Q9H773 dCTP pyrophosphatase 1

2.2e-26

55.36

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Query:  SYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAA
        S+ PE      +L+++R + AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   WS  ER  L+EE+SDVL+YLV LA  C +DL  A 
Subjt:  SYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAA

Query:  LSKLVKNANKYP
        LSK+  N  +YP
Subjt:  LSKLVKNANKYP

Q9QY93 dCTP pyrophosphatase 1

5.9e-27

50.86

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Query:  ENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLG
        ++ +  P + + + +L+++R + AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   W   ER  L+EE+SDVL+YLV LA  C +DL 
Subjt:  ENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLG

Query:  HAALSKLVKNANKYPV
         A +SK+  N  +YPV
Subjt:  HAALSKLVKNANKYPV

Arabidopsis top hits

e value

%identity

Alignment

AT3G25400.1 CONTAINS InterPro DOMAIN/s: NTP Pyrophosphohydrolase MazG-related, RS21-C6 (InterPro:IPR011394), EAR (InterPro:IPR009039), NTP pyrophosphohydrolase MazG, putative catalytic core (InterPro:IPR004518); Has 1123 Blast hits to 1121 proteins in 452 species: Archae - 22; Bacteria - 753; Metazoa - 81; Fungi - 3; Plants - 83; Viruses - 0; Other Eukaryotes - 181 (source: NCBI BLink).

2.2e-37

64.35

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Query:  NRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGH
        N+  E  ++ + VSLQ L   + +FA+ R WE+YHSPRNLLLA+VGEVGELSEIFQWKGEV RG P+W   E+ HL EE+SDVLLYLVRL+D CG+DLG 
Subjt:  NRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGH

Query:  AALSKLVKNANKYPV
        AAL K+  NA KYPV
Subjt:  AALSKLVKNANKYPV

Sequences

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CDS sequence

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ATGGAGAATCGTTCTTACGAACCGGAGAAAAACGCCAAAGACGTCTCACTGCAGGAACTCAGAGACATGCTGGCAGAGTTCGCTCGAGTACGAGGATGGGAACAATACCA
CAGCCCAAGAAACCTTCTCCTAGCACTTGTTGGTGAGGTCGGAGAGCTATCGGAGATATTCCAGTGGAAGGGGGAGGTGGAGAGGGGGCTGCCAAACTGGAGCGCGGCGG
AGAGAGAGCATTTGGAAGAAGAGGTGTCTGATGTGTTACTCTATTTGGTGCGTCTCGCCGATGTGTGTGGCCTTGATTTGGGCCATGCCGCTCTCTCAAAGCTCGTCAAA
AATGCCAACAAGTACCCTGTCGCCGCTTTCGCGCGCGCGCTTCCATGA

mRNA sequence

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ACAGATCAAAGAGAGAGAGAAATGGAGAATCGTTCTTACGAACCGGAGAAAAACGCCAAAGACGTCTCACTGCAGGAACTCAGAGACATGCTGGCAGAGTTCGCTCGAGT
ACGAGGATGGGAACAATACCACAGCCCAAGAAACCTTCTCCTAGCACTTGTTGGTGAGGTCGGAGAGCTATCGGAGATATTCCAGTGGAAGGGGGAGGTGGAGAGGGGGC
TGCCAAACTGGAGCGCGGCGGAGAGAGAGCATTTGGAAGAAGAGGTGTCTGATGTGTTACTCTATTTGGTGCGTCTCGCCGATGTGTGTGGCCTTGATTTGGGCCATGCC
GCTCTCTCAAAGCTCGTCAAAAATGCCAACAAGTACCCTGTCGCCGCTTTCGCGCGCGCGCTTCCATGAACTTCGCGCCCCCTTCTCTTTCCTCCCTTCGCTGCTTTTCT
GTTTCTGTACTCGTTTCTGCTTCATATTGATATGCACGGAGATCCGTCTCAGTTTACTGGATACTCACACCGCTCTTATTCTTTAAATATTCTCCTT

Protein sequence

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MENRSYEPEKNAKDVSLQELRDMLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEREHLEEEVSDVLLYLVRLADVCGLDLGHAALSKLVK
NANKYPVAAFARALP

Carg17944 (gene) of Silver-seed gourd (SMH-JMG-627) v2 genome