CuGenDBv2

Gene ID	Carg19432
Organism	Cucurbita argyrosperma subsp. argyrosperma cv. SMH-JMG-627 (Silver-seed gourd (SMH-JMG-627) v2)
Description	DNA mismatch repair protein MLH3 isoform X2
Genome location	Carg_Chr16:10179598..10181308
RNA-Seq Expression	Carg19432
Synteny	Carg19432
Gene Ontology terms	NA
InterPro domains	IPR036890 - Histidine kinase/HSP90-like ATPase superfamily

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAG6577819.1 DNA mismatch repair protein MLH3, partial [Cucurbita argyrosperma subsp. sororia]

2.2e-68

98.48

Show/hide

Query:  SAISKVVEELIHNTLNADGWKVVKSRILRKETDMLASWKILNEFGFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYSKVMKGCKCLCLGID
        +AI+KVVEELIHNTLNADGWKVVKSRILRKETDMLASWKILNEFGFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYSKVMKGCKCLCLGID
Subjt:  SAISKVVEELIHNTLNADGWKVVKSRILRKETDMLASWKILNEFGFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYSKVMKGCKCLCLGID

Query:  DDMEDVGTTGNSFIIPQLHYIVKIAYHALRPC
        DDMEDVGTTGNSFIIPQLHYIVKIAYHALRPC
Subjt:  DDMEDVGTTGNSFIIPQLHYIVKIAYHALRPC

KAG7015858.1 DNA mismatch repair protein MLH3, partial [Cucurbita argyrosperma subsp. argyrosperma]

1.1e-83

100

Show/hide

Query:  MRRSTDVSKRNWLLSLRTVGKCGGSAISKVVEELIHNTLNADGWKVVKSRILRKETDMLASWKILNEFGFTTSDAQGGTFGSRGQAFASISDVSVVEIIT
        MRRSTDVSKRNWLLSLRTVGKCGGSAISKVVEELIHNTLNADGWKVVKSRILRKETDMLASWKILNEFGFTTSDAQGGTFGSRGQAFASISDVSVVEIIT
Subjt:  MRRSTDVSKRNWLLSLRTVGKCGGSAISKVVEELIHNTLNADGWKVVKSRILRKETDMLASWKILNEFGFTTSDAQGGTFGSRGQAFASISDVSVVEIIT

Query:  KACGRANGYSKVMKGCKCLCLGIDDDMEDVGTTGNSFIIPQLHYIVKIAYHALRPC
        KACGRANGYSKVMKGCKCLCLGIDDDMEDVGTTGNSFIIPQLHYIVKIAYHALRPC
Subjt:  KACGRANGYSKVMKGCKCLCLGIDDDMEDVGTTGNSFIIPQLHYIVKIAYHALRPC

XP_038903642.1 DNA mismatch repair protein MLH3 isoform X1 [Benincasa hispida]

5.2e-22

53.66

Show/hide

Query:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS
        ++KVVEEL++N+L+A   K+          VK     S I R    +L    + ++F      D++ GTFG RG+A ASISDVS+VEIIT+ACGRANGY 
Subjt:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS

Query:  KVMKGCKCLCLGIDDDMEDVGTT
        KV+KGCKCL LGIDDDMEDVGTT
Subjt:  KVMKGCKCLCLGIDDDMEDVGTT

XP_038903643.1 DNA mismatch repair protein MLH3 isoform X2 [Benincasa hispida]

5.2e-22

53.66

Show/hide

Query:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS
        ++KVVEEL++N+L+A   K+          VK     S I R    +L    + ++F      D++ GTFG RG+A ASISDVS+VEIIT+ACGRANGY 
Subjt:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS

Query:  KVMKGCKCLCLGIDDDMEDVGTT
        KV+KGCKCL LGIDDDMEDVGTT
Subjt:  KVMKGCKCLCLGIDDDMEDVGTT

XP_038903645.1 DNA mismatch repair protein MLH3 isoform X4 [Benincasa hispida]

5.2e-22

53.66

Show/hide

Query:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS
        ++KVVEEL++N+L+A   K+          VK     S I R    +L    + ++F      D++ GTFG RG+A ASISDVS+VEIIT+ACGRANGY 
Subjt:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS

Query:  KVMKGCKCLCLGIDDDMEDVGTT
        KV+KGCKCL LGIDDDMEDVGTT
Subjt:  KVMKGCKCLCLGIDDDMEDVGTT

TrEMBL top hits

e value

%identity

Alignment

A0A0A0L1I8 Uncharacterized protein

5.6e-22

52.85

Show/hide

Query:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS
        ++KVVEEL++N+L+A   K+          VK     S I R    +L    + ++F     +D +GGTFG RG+A ASISD S+VEIIT+ACGRANGY 
Subjt:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS

Query:  KVMKGCKCLCLGIDDDMEDVGTT
        KV+KGCKCL LGIDDDMED GTT
Subjt:  KVMKGCKCLCLGIDDDMEDVGTT

A0A6J1DVD7 DNA mismatch repair protein MLH3 isoform X2

4.3e-22

52.85

Show/hide

Query:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS
        +++VVEEL++N+L+A   K+          VK     S I R    +L    + ++F      DA+G TFG RG++ ASISDVS+VEIITK CGRANGY 
Subjt:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS

Query:  KVMKGCKCLCLGIDDDMEDVGTT
        KVMKGCKCL LG+DDDMEDVGTT
Subjt:  KVMKGCKCLCLGIDDDMEDVGTT

A0A6J1DVM2 DNA mismatch repair protein MLH3 isoform X5

4.3e-22

52.85

Show/hide

Query:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS
        +++VVEEL++N+L+A   K+          VK     S I R    +L    + ++F      DA+G TFG RG++ ASISDVS+VEIITK CGRANGY 
Subjt:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS

Query:  KVMKGCKCLCLGIDDDMEDVGTT
        KVMKGCKCL LG+DDDMEDVGTT
Subjt:  KVMKGCKCLCLGIDDDMEDVGTT

A0A6J1DWT6 DNA mismatch repair protein MLH3 isoform X4

4.3e-22

52.85

Show/hide

Query:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS
        +++VVEEL++N+L+A   K+          VK     S I R    +L    + ++F      DA+G TFG RG++ ASISDVS+VEIITK CGRANGY 
Subjt:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS

Query:  KVMKGCKCLCLGIDDDMEDVGTT
        KVMKGCKCL LG+DDDMEDVGTT
Subjt:  KVMKGCKCLCLGIDDDMEDVGTT

A0A6J1E0G9 DNA mismatch repair protein MLH3 isoform X3

4.3e-22

52.85

Show/hide

Query:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS
        +++VVEEL++N+L+A   K+          VK     S I R    +L    + ++F      DA+G TFG RG++ ASISDVS+VEIITK CGRANGY 
Subjt:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS

Query:  KVMKGCKCLCLGIDDDMEDVGTT
        KVMKGCKCL LG+DDDMEDVGTT
Subjt:  KVMKGCKCLCLGIDDDMEDVGTT

SwissProt top hits

e value

%identity

Alignment

F4JN26 DNA mismatch repair protein MLH3

2.8e-18

46.34

Show/hide

Query:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS
        +++VVEEL+ N+L+A   KV          VK     S + R +  +L      ++F  FT  +    TFG RG+A ASISD+S++E+ TKA GR NGY 
Subjt:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS

Query:  KVMKGCKCLCLGIDDDMEDVGTT
        KVMKG KCL LGIDDD +D GTT
Subjt:  KVMKGCKCLCLGIDDDMEDVGTT

Arabidopsis top hits

e value

%identity

Alignment

AT4G35520.1 MUTL protein homolog 3

2.0e-19

46.34

Show/hide

Query:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS
        +++VVEEL+ N+L+A   KV          VK     S + R +  +L      ++F  FT  +    TFG RG+A ASISD+S++E+ TKA GR NGY 
Subjt:  ISKVVEELIHNTLNADGWKV----------VK-----SRILRKETDMLASWKILNEF-GFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS

Query:  KVMKGCKCLCLGIDDDMEDVGTT
        KVMKG KCL LGIDDD +D GTT
Subjt:  KVMKGCKCLCLGIDDDMEDVGTT

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGCGGCGGAGCACAGACGTCTCGAAGAGGAATTGGCTTTTGAGCCTACGAACCGTCGGCAAATGTGGCGGTAGCGCCATCTCGAAGGTCGTGGAAGAGCTTATTCATAA
TACCTTGAATGCTGATGGGTGGAAGGTGGTGAAAAGTAGAATTCTAAGGAAGGAAACAGACATGTTAGCAAGCTGGAAAATACTTAATGAATTTGGATTTACTACCTCAG
ATGCCCAAGGTGGAACGTTTGGCTCCCGAGGACAGGCATTTGCTTCGATTTCAGATGTATCGGTGGTGGAGATCATAACCAAAGCATGTGGGAGGGCAAATGGATATTCT
AAAGTCATGAAGGGTTGCAAATGCTTGTGTCTTGGAATTGATGATGATATGGAAGATGTTGGTACTACTGGTAACAGTTTCATCATCCCTCAGTTACATTATATTGTGAA
AATCGCTTACCATGCTTTAAGACCTTGCTAG

mRNA sequence

Show/hide mRNA sequence

Protein sequence

Show/hide protein sequence

MRRSTDVSKRNWLLSLRTVGKCGGSAISKVVEELIHNTLNADGWKVVKSRILRKETDMLASWKILNEFGFTTSDAQGGTFGSRGQAFASISDVSVVEIITKACGRANGYS
KVMKGCKCLCLGIDDDMEDVGTTGNSFIIPQLHYIVKIAYHALRPC

Carg19432 (gene) of Silver-seed gourd (SMH-JMG-627) v2 genome