CuGenDBv2

Gene ID	Carg24791
Organism	Cucurbita argyrosperma subsp. argyrosperma cv. SMH-JMG-627 (Silver-seed gourd (SMH-JMG-627) v2)
Description	DNA topoisomerase
Genome location	Carg_Chr14:11371068..11389110
RNA-Seq Expression	Carg24791
Synteny	Carg24791
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0005634 - nucleus (cellular component) GO:0003677 - DNA binding (molecular function) GO:0003917 - DNA topoisomerase type I activity (molecular function)
InterPro domains	IPR000380 - DNA topoisomerase, type IA IPR003601 - DNA topoisomerase, type IA, domain 2 IPR003602 - DNA topoisomerase, type IA, DNA-binding domain IPR006171 - TOPRIM domain IPR013497 - DNA topoisomerase, type IA, central IPR013824 - DNA topoisomerase, type IA, central region, subdomain 1 IPR013825 - DNA topoisomerase, type IA, central region, subdomain 2 IPR013826 - DNA topoisomerase, type IA, central region, subdomain 3 IPR023405 - DNA topoisomerase, type IA, core domain IPR023406 - DNA topoisomerase, type IA, active site IPR034144 - DNA topoisomerase 3-like, TOPRIM domain

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6582102.1 DNA topoisomerase 3-beta, partial [Cucurbita argyrosperma subsp. sororia]

0.0e+00

100

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Query:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL
        MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL

Query:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW
        LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW
Subjt:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA
        EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA
Subjt:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP
        AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP

Query:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF
        LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF
Subjt:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF

XP_022955609.1 DNA topoisomerase 3-beta isoform X1 [Cucurbita moschata]

0.0e+00

99.88

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Query:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL
        MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL

Query:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW
        LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVR+LLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW
Subjt:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA
        EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA
Subjt:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP
        AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP

Query:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF
        LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF
Subjt:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF

XP_022979706.1 DNA topoisomerase 3-beta isoform X1 [Cucurbita maxima]

0.0e+00

99.54

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Query:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL
        MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNE RKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL

Query:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW
        LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW
Subjt:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKY+RTKIQFSIAGEIFNCTGSSV+VKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA
        EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGID LYGA
Subjt:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP
        AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP

Query:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF
        LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF
Subjt:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF

XP_023528530.1 DNA topoisomerase 3-beta isoform X1 [Cucurbita pepo subsp. pepo]

0.0e+00

99.42

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Query:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL
        MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIK ESNPKAHIRQHL
Subjt:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGN+YRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL

Query:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW
        LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW
Subjt:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKY+RTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA
        EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA
Subjt:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP
        AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP

Query:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGS--RGRGRGRGRGRGRGRSSGKLMDPKMSFRDF
        LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGS  RGRGRGRGRGRGRGRSSGKLMDPKMSFRDF
Subjt:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGS--RGRGRGRGRGRGRGRSSGKLMDPKMSFRDF

XP_038891105.1 DNA topoisomerase 3-beta isoform X1 [Benincasa hispida]

0.0e+00

94.58

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Query:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL
        MVAS+VLMVAEKPSIALSIASALSHGQMSTRKGST+VHEFDGRFLGHHAHYKVTSVIGHVFSIDFPA FQDWK+TDPLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNE RKKVYRARFSSVTEKDILKALDNLV+PN+NEALAVDARQEIDLKVGV+FTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTF PEKFWSVCPYIMQNGYELNLDWERG+LFDCDV  MFQKRV+EDGIAEVT+ISEKQE+KVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL

Query:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW
        LKVASSALG+GPQ+AMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLH+L+KN EWGDYVRMLLSDGYSKPRSGTDVGDHPPITPM LATEDM+GRDAW
Subjt:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKY+RTKIQFSIAGE+FNCTGS V+VKGFTSIMPWLAVNEKKLPQFLKG+KIEVA+VDLYQGNT+PPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRL PTNLGITL+RGYQCIDPDLCLPDIRSFIEQQIT VAKGQADH SVVQNVLQQFKQKY YFVKKIDHMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA
        EAQFSPLA+SGRALSKCGKCLRYMKFISSQPQRLYCG CEEVYYLPQ+GAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA
Subjt:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP
        AKTNPSSGASSKGMGMPCFLC HPTCRHSLITQGVCACPECSGTLVLDPV APNWKLNCNKCNCLVFLPQGAHRI+T NEKCA+CDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP

Query:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGR-GRGRGRSSGKLMDPKMSFRDF
        LEGGATLFVGCILCDEFLHSLLEMKHGKS FRGRGSRGRGRGRGR GRGRGR+SG+ MDPKMSFRDF
Subjt:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGR-GRGRGRSSGKLMDPKMSFRDF

TrEMBL top hits

e value

%identity

Alignment

A0A0A0L9C7 DNA topoisomerase

0.0e+00

93.77

Show/hide

Query:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL
        MVA +VLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHA+YKVTSVIGHVFSIDF A FQDWK+TDPLDLFQASVIKTESNPKAHI QHL
Subjt:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGN  RKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYI+Q GYELNLDWERG+LFDCDV  MFQKRV+EDGIAEVT+ISEKQE+KVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL

Query:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW
        LKVASSALG+GPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLH+LVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPM LATEDM+GRDAW
Subjt:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKY+RTKIQFSIAGEIFNCTGS V VKGFTSIMPWLAVNEKKLPQFLKG+KIEVA+VDLYQGNT+PPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIE QIT VAKGQADH SVVQ+VLQQF+QKYSYFVKKIDHMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA
        EAQFSPLA+SGRALSKCGKCLRYMKFISSQPQRLYCG CEEVYYLPQ+G IKLYKELTCPLDNFELLI+SLPGPEGKSFPLCPYCYNSPPFEGI+TLYGA
Subjt:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP
        +K NPSSG SSKGMGMPCF+CPHPTCRHSLITQGVCACPECSGTLVLDPV APNWKLNCNKCNCLVFLP+GAHRI+TT +KCA+CDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP

Query:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGR-GRGRSSGKLMDPKMSFRDF
        LE GATLFVGCILCDEFLHSLLEMKHGKSF R RGSRGRGRGRGRGR GRGRSSGK MDPKMSFRDF
Subjt:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGR-GRGRSSGKLMDPKMSFRDF

A0A1S3AYH7 DNA topoisomerase

0.0e+00

93.67

Show/hide

Query:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL
        MVAS+VLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHA+YKVTSVIGH+FSIDF A FQDWK T+PLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGN  RKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERG+LFDCDV  MFQKRV+EDGIAEVT+ISEKQE+KVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL

Query:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW
        LKVASSALG+GPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLH+LVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPM  ATEDM+GRDAW
Subjt:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKY+RTKIQFSIAGEIFNCTGS V VKGFTSIMPWLAVNEKKLPQFLKG+KIEVA+VDLYQGNT+PPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIE QIT VAKGQADH SVV++VLQQFKQKYSYFVKKID MDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA
        EAQFSPLA+SGRALSKCGKCLRYMKFISSQPQRLYCG CEEVYYLPQ+G IKLYKELTCPLDNFELLI SLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA
Subjt:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP
        +KTNPSSG SSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPV APNWKLNCNKCNCLVFLPQGAHRI+TT++KCA+CDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP

Query:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGR---GRGRSSGKLMDPKMSFRDF
        LE GATLFVGCILCDEFLHSLLEMKHG SF R R SRGRGRGRGRGR   GRGR+SGK MDPKMSFRDF
Subjt:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGR---GRGRSSGKLMDPKMSFRDF

A0A5A7VKD3 DNA topoisomerase

0.0e+00

93.46

Show/hide

Query:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL
        MVAS+VLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHA+YKVTSVIGH+FSIDF A FQDWK T+PLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGN  RKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERG+LFDCDV  MFQKRV+EDGIAEVT+ISEKQE+KVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL

Query:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW
        LKVASSALG+GPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLH+LVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPM  ATEDM+GRDAW
Subjt:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKY+RTKIQFSIAGEIFNCTGS V VKGFTSIMPWLAVNEKKLPQFLKG+KIEVA+VDLYQGNT+PPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIE QIT VAKGQADH SVV++VLQQFKQKYSYFVKKID MDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA
        EAQFSPLA+SGRALSKCGKCLRYMKFISSQPQRLYCG CEEVYYLPQ+G IKLYKELTCPLDNFELLI SLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA
Subjt:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP
        +KTNPSSG SSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPV APNWKLNCNKCNCLVFLPQGAHRI+TT++KCA+CDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP

Query:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGR-----GRGRSSGKLMDPKMSFRDF
        LE GATLFVGCILCDEFLHSLLEMKHG SF R R SRGRGRGRGRGR     GRGR+SGK MDPKMSFRDF
Subjt:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGR-----GRGRSSGKLMDPKMSFRDF

A0A6J1GWS0 DNA topoisomerase

0.0e+00

99.88

Show/hide

Query:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL
        MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL

Query:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW
        LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVR+LLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW
Subjt:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA
        EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA
Subjt:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP
        AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP

Query:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF
        LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF
Subjt:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF

A0A6J1IRJ0 DNA topoisomerase

0.0e+00

99.54

Show/hide

Query:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL
        MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNE RKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNL

Query:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW
        LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW
Subjt:  LKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKY+RTKIQFSIAGEIFNCTGSSV+VKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALF

Query:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA
        EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGID LYGA
Subjt:  EAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGA

Query:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP
        AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP
Subjt:  AKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTP

Query:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF
        LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF
Subjt:  LEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF

SwissProt top hits

e value

%identity

Alignment

F4ISQ7 DNA topoisomerase 3-beta

0.0e+00

76.42

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Query:  VLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHLSREAR
        VLMVAEKPSIALSIAS LSHGQMSTR+GSTEVHEFDG F G  AHY+VTSVIGHVFS+DFP ++Q+W   DP DLF A +IK ESNPKAHI +HLS EAR
Subjt:  VLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHLSREAR

Query:  GCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYGNLDSR
        GC  +VLWLDCDREGENICFEVIE TGF   + ++KVYRARFSSVTEKDI KA+DNLVEPNR+EALAVDARQEIDLKVGV+F+RFQT++FQGKY NLD R
Subjt:  GCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYGNLDSR

Query:  LISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNLLKVAS
        +ISYGPCQTPTLGFCVQR++ I TFKPEKFW++ PYI ++GYEL L+WER RLFD + AT+FQK V+E   A+V  +SEKQE K RP+GLNTVNLLKVAS
Subjt:  LISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNLLKVAS

Query:  SALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAWRLYQY
        SALG+GPQ AM LAERLYTQGFISYPRTESTAYPSSFDF  TL + V NP WG YV+ LLSDG+  P+SGTD GDHPPITPM  ATE MVG DAWRLYQY
Subjt:  SALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAWRLYQY

Query:  VCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHGIGTDA
        VCQHF+G++S +CKY+RTK++ SI GE F+CTG  V  KGFT+IMPW AV+EKKLP FLKG++IEV +V+LY+GNT+PPDYL+ESELISLMEKHGIGTDA
Subjt:  VCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHGIGTDA

Query:  SIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALFEAQFS
        SI VHINNIGERNYVQVQ+GR++VPT LGITLIRGYQCIDPDLCLPDIRSFIEQQIT VAKGQADH  VVQ+V+QQF++K+SYFV++I+HMDALFEAQFS
Subjt:  SIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALFEAQFS

Query:  PLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGAAKTNP
        PLA+SGRALSKCGKCLRYMK I++ P RL+CGTCEEVYYLPQ+G +KLYKELTCPLDNFEL+I+S+PGPEGKSFPLCPYCYNSPPFEGIDTL+GA+KT  
Subjt:  PLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGAAKTNP

Query:  SSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTPLEGGA
        +   +  G GMPC LCPHPTC+HS+  QGVCACPEC GTLVLDPV  P WKLNCN C+C+V LP+GAHRI TT+ +C ECDS IIE+DFNKKTTPLE GA
Subjt:  SSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTPLEGGA

Query:  TLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF
        TL  GC+LCDE L SL+E+KHG+SF R RG RGRGRGRGRGRG GR   K +DPKMSFRDF
Subjt:  TLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF

O95985 DNA topoisomerase 3-beta-1

1.4e-265

52.6

Show/hide

Query:  SVLMVAEKPSIALSIASALSHGQMSTRK---GSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLF-QASVIKTESNPKAHIRQHL
        +VLMVAEKPS+A SIA  LS G +S+ K   G+  VHE+ G F G    +K+TSV GHV ++DF  ++  W   DP +LF QA   K E+NPK ++ + L
Subjt:  SVLMVAEKPSIALSIASALSHGQMSTRK---GSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLF-QASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECT------GFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTF
          E RGCD +VLWLDCD+EGENICFEV++          GG    K V+RARFSS+T+ DI  A+  L EP+ NEAL+VDARQE+DL++G +FTRFQT +
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECT------GFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTF

Query:  FQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYI-MQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPS
        FQGKYG+LDS LIS+GPCQTPTLGFCV+RH +I +FKPE +W +   +       L LDW+R R+FD ++A MF      +  A+V   S K+++K RP 
Subjt:  FQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYI-MQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPS

Query:  GLNTVNLLKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATED
         LNTV +L+VASS+LG GPQ AMQ AERLYTQG+ISYPRTE+T YP +FD KG+L     +P W D V+ LL++G ++PR G D GDHPPITPM  ATE 
Subjt:  GLNTVNLLKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATED

Query:  MVGRDAWRLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVN-EKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESEL
         +G DAWRLY+Y+ +HFI ++S DCKYL++ I F I  E+F C+G +V+  GFT +MPW +V  E+ LP   +G    V +V + +  T+PPDYL+E+EL
Subjt:  MVGRDAWRLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVN-EKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESEL

Query:  ISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKK
        I+LMEKHGIGTDASIPVHINNI +RNYV V++GRRL PTNLGI L+ GY  ID +L LP IRS +E+Q+  +A+G+AD+  V+ + L  FK+K+ YFV  
Subjt:  ISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKK

Query:  IDHMDALFEAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFE
        I  MD L E  FSPLA +G+ LS+CGKC R+MK+I ++P RL+C  C+E Y LPQ G IKLYKEL CPLD+FEL+++S  G  GKS+PLCPYCYN PPF 
Subjt:  IDHMDALFEAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFE

Query:  GIDTLYGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPEC-SGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIE
         +                 KGMG  C  C HP+C+HSL   G+  C EC SG LVLDP   P WK+ CNKCN +    + AHR+  + + C+ C++ +++
Subjt:  GIDTLYGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPEC-SGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIE

Query:  VDFNKKTTPLEGGATLFVGCILCDEFLHSLLEMKHGKSFF-RGRGSRGRGRGRGRGRGRGRSSGK
        VDFNK  +PL G  T  +GC+ CD     L+E+KH  S     RG  GR +GRGRGR R R  GK
Subjt:  VDFNKKTTPLEGGATLFVGCILCDEFLHSLLEMKHGKSFF-RGRGSRGRGRGRGRGRGRGRSSGK

O96651 DNA topoisomerase 3-beta

2.1e-240

48.95

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Query:  SVLMVAEKPSIALSIASALSHGQMSTRKGS---TEVHEFDGRFLGH-HAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL
        SVLMVAEKPS+A S+A  LS+G+ + ++G+      HE+ G F      H+++TSV GHV S+DF  ++  W   DP+ LF  +  K E+NPK ++R+ L
Subjt:  SVLMVAEKPSIALSIASALSHGQMSTRKGS---TEVHEFDGRFLGH-HAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFG-GNEYRKKV-YRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGK
        + EARGCD LVLWLDCD+EGENICFEV++       N Y  +V YRA FS++TEKDI KA++ L  PN NEA +VDARQE+DL++G +FTRFQT FFQ +
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFG-GNEYRKKV-YRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGK

Query:  YGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTV
        YG+LDS LISYGPCQTPTLGFCV+RH  I TFKPE FW +   ++    E+ L+W RGR+F  D+A M   RV E   A V  ++ K+  K +P  LNTV
Subjt:  YGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTV

Query:  NLLKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRD
         L+++ SS LG GP  AMQ+AERLYTQG+ISYPRTE+  YP++FD    LH L  + ++G+  R +L D    PR G D GDHPPITPM L       RD
Subjt:  NLLKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRD

Query:  AWRLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAV-NEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLME
         WR+Y+++C+HF+G++S D KY  T  + S+  E F+CT S ++  GFT +M W A   ++  P F++G ++ +  V L +  T PPDYL+ESELI+LME
Subjt:  AWRLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAV-NEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLME

Query:  KHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMD
        +HGIGTDASIPVHINNI +RNYV ++ GR+L+PT LGI L+ GYQ IDP+L LP +R+ +E+ +T +A+G A+   V+++ ++ FK K+ YFVK ID MD
Subjt:  KHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMD

Query:  ALFEAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTL
        ALFE  FSPLAESG+A S+CGKC RYMK+I ++P RL+C  C+E Y LP  G +K+Y+E  CPLD+F+LL FS  G +G+S+P CPYCYN PPF  +  L
Subjt:  ALFEAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTL

Query:  YGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPEC-SGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNK
         G                  C  C +  C HSL T G+ +C EC +G LVLD   AP WKL CN+C+ ++   +GA +I     KC EC +  + V +  
Subjt:  YGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPEC-SGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNK

Query:  KTTPLEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSG
          +  + G+    GCI C      L+E KH     R   S G  RG   GRG G   G
Subjt:  KTTPLEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSG

Q0J0S6 DNA topoisomerase 3-beta

0.0e+00

72.7

Show/hide

Query:  VASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHLS
        +A +VLMVAEKPSIALSIASALS G+MSTRKGST+VHEFDG F G HA +KVTSVIGHV S+DFP  +Q+W+ TDP+DLF A V+++E NPKAHIR+HL+
Subjt:  VASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHLS

Query:  REARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYGN
        +EARGC  LVLWLDCDREGENIC+EVI+CTG   +E  ++++RA+FSSVTEKDI+ A++NLV P+++EALAVDARQEIDLKVGV+FTRFQT +FQGKYGN
Subjt:  REARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYGN

Query:  LDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNLL
        LDSR+ISYGPCQTPTLGFCVQR+ QITTFKPEKFWS+  Y++++G E+ L+W+R +LFD DV  MFQK V  DGI +VT IS K+E K RP GLNTVNLL
Subjt:  LDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNLL

Query:  KVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAWR
        KVASSALG GPQ AM LAERLYTQGFISYPRTESTAYPSSFDF+  L +L  NP W + VR LL  G+ KP+ G D GDHPPITPM LATE+ +G DAWR
Subjt:  KVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAWR

Query:  LYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHGI
        LYQY+CQHFIG++S DC+Y RT I+F+  GE F+C G+ V  KGFTSIMPWLAV+E  +P + KG  + + KVD+Y+G+T+PPDYLSESELISLMEK+GI
Subjt:  LYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHGI

Query:  GTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALFE
        GTDASIPVH+NNI ERNYVQV +GRRLVPT LG TLIRGYQCID DLCLPDIR FIEQQIT +AKG+ADH  VVQ+VLQQF +KYSYFVKKI++MDALFE
Subjt:  GTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALFE

Query:  AQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGAA
        AQFSPLA+SGR LSKCGKC RYMK+IS+QP RLYC TCEEVYYLPQ G+IKLYKE+ CPLD FELL+FS+ GP+ KSFPLCP+CYNSPPFEGID L+GA 
Subjt:  AQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGAA

Query:  KTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTPL
        K +  +G   KG GMPCFLC HPTC+ S+ITQGVCACPEC+GTL+LDPV AP W+L CN+CNC+V LP  AH+I+TT++KC  C+STIIEVDFNKKTTPL
Subjt:  KTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTPL

Query:  EGGATLFVGCILCDEFLHSLLEMKHGKSFF--RGRGSRGRGRGRGRGRGRG-RSSGKLMDPKMSFRDF
        + GATL  GCILCDE LHSL+EMKHGKSFF  RGRG RGRGRGRGRG  RG R S +  DPKMSFRDF
Subjt:  EGGATLFVGCILCDEFLHSLLEMKHGKSFF--RGRGSRGRGRGRGRGRGRG-RSSGKLMDPKMSFRDF

Q9Z321 DNA topoisomerase 3-beta-1

3.4e-267

53.36

Show/hide

Query:  SVLMVAEKPSIALSIASALSHGQMSTRK---GSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLF-QASVIKTESNPKAHIRQHL
        +VLMVAEKPS+A SIA  LS G MS+ K   G+  VH++ G F G   H+K+TSV GHV ++DF  ++  W   DP +LF QA   K E+NPK ++ + L
Subjt:  SVLMVAEKPSIALSIASALSHGQMSTRK---GSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLF-QASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIEC---TGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQG
          E RGCD +VLWLDCD+EGENICFEV++         +   K V+RARFSS+T+ DI  A+  L EP+ NEAL+VDARQE+DL++G +FTRFQT +FQG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIEC---TGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQG

Query:  KYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYE-LNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLN
        KYG+LDS LIS+GPCQTPTLGFCV+RH +I +FKPE +W +   +  +  E L LDW+R R+FD ++A MF      +  A V   S K+++K RP  LN
Subjt:  KYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYE-LNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLN

Query:  TVNLLKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVG
        TV +L+VASSALG GPQ AMQ+AERLYTQG+ISYPRTE+T YP +FD KG+L     +P W D V+ LL++G ++PR G D GDHPPITPM  ATE  +G
Subjt:  TVNLLKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVG

Query:  RDAWRLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVN-EKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISL
         DAWRLY+Y+ +HFI ++S DCKYL++ I F I  E F C G +V+  GFT IMPW +V  E+ LP   KG    V +V + +  TSPPDYL+E+ELI+L
Subjt:  RDAWRLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVN-EKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISL

Query:  MEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDH
        MEKHGIGTDASIPVHINNI +RNYV V++GRRL PTNLGI L+ GY  ID +L LP IRS +E+Q+  +A+G+AD+  V+ + L  FK+K+ YFV  I  
Subjt:  MEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDH

Query:  MDALFEAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGID
        MD L E  FSPLA +G+ LS+CGKC R+MK+I ++P RL+C  C+E Y LPQ G IKLYKEL CPLD+FEL+++S  G  GKS+PLCPYCYN PPF  + 
Subjt:  MDALFEAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGID

Query:  TLYGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPEC-SGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDF
                        KGMG  C  C HPTC+HSL   G+  C EC +G LVLDP   P WK+ CN CN +    + AHR+  + + C  C++ +++VDF
Subjt:  TLYGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPEC-SGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDF

Query:  NKKTTPLEGGATLFVGCILCDEFLHSLLEMKHGKSFF-RGRGSRGRGRGRGRGRGRGRSSGK
        NK  +PL G  T   GCI CD     L+E+KH  S     RG  GR +GRGRGRGR R  GK
Subjt:  NKKTTPLEGGATLFVGCILCDEFLHSLLEMKHGKSFF-RGRGSRGRGRGRGRGRGRGRSSGK

Arabidopsis top hits

e value

%identity

Alignment

AT2G32000.1 DNA topoisomerase, type IA, core

0.0e+00

76.42

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Query:  VLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHLSREAR
        VLMVAEKPSIALSIAS LSHGQMSTR+GSTEVHEFDG F G  AHY+VTSVIGHVFS+DFP ++Q+W   DP DLF A +IK ESNPKAHI +HLS EAR
Subjt:  VLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHLSREAR

Query:  GCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYGNLDSR
        GC  +VLWLDCDREGENICFEVIE TGF   + ++KVYRARFSSVTEKDI KA+DNLVEPNR+EALAVDARQEIDLKVGV+F+RFQT++FQGKY NLD R
Subjt:  GCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYGNLDSR

Query:  LISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNLLKVAS
        +ISYGPCQTPTLGFCVQR++ I TFKPEKFW++ PYI ++GYEL L+WER RLFD + AT+FQK V+E   A+V  +SEKQE K RP+GLNTVNLLKVAS
Subjt:  LISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNLLKVAS

Query:  SALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAWRLYQY
        SALG+GPQ AM LAERLYTQGFISYPRTESTAYPSSFDF  TL + V NP WG YV+ LLSDG+  P+SGTD GDHPPITPM  ATE MVG DAWRLYQY
Subjt:  SALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAWRLYQY

Query:  VCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHGIGTDA
        VCQHF+G++S +CKY+RTK++ SI GE F+CTG  V  KGFT+IMPW AV+EKKLP FLKG++IEV +V+LY+GNT+PPDYL+ESELISLMEKHGIGTDA
Subjt:  VCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHGIGTDA

Query:  SIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALFEAQFS
        SI VHINNIGERNYVQVQ+GR++VPT LGITLIRGYQCIDPDLCLPDIRSFIEQQIT VAKGQADH  VVQ+V+QQF++K+SYFV++I+HMDALFEAQFS
Subjt:  SIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALFEAQFS

Query:  PLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGAAKTNP
        PLA+SGRALSKCGKCLRYMK I++ P RL+CGTCEEVYYLPQ+G +KLYKELTCPLDNFEL+I+S+PGPEGKSFPLCPYCYNSPPFEGIDTL+GA+KT  
Subjt:  PLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGAAKTNP

Query:  SSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTPLEGGA
        +   +  G GMPC LCPHPTC+HS+  QGVCACPEC GTLVLDPV  P WKLNCN C+C+V LP+GAHRI TT+ +C ECDS IIE+DFNKKTTPLE GA
Subjt:  SSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTPLEGGA

Query:  TLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF
        TL  GC+LCDE L SL+E+KHG+SF R RG RGRGRGRGRGRG GR   K +DPKMSFRDF
Subjt:  TLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF

AT2G32000.2 DNA topoisomerase, type IA, core

0.0e+00

75.22

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Query:  HVFSI---DFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDI
        H+ S+   DFP ++Q+W   DP DLF A +IK ESNPKAHI +HLS EARGC  +VLWLDCDREGENICFEVIE TGF   + ++KVYRARFSSVTEKDI
Subjt:  HVFSI---DFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDI

Query:  LKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWER
         KA+DNLVEPNR+EALAVDARQEIDLKVGV+F+RFQT++FQGKY NLD R+ISYGPCQTPTLGFCVQR++ I TFKPEKFW++ PYI ++GYEL L+WER
Subjt:  LKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWER

Query:  GRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNLLKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNP
         RLFD + AT+FQK V+E   A+V  +SEKQE K RP+GLNTVNLLKVASSALG+GPQ AM LAERLYTQGFISYPRTESTAYPSSFDF  TL + V NP
Subjt:  GRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNLLKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNP

Query:  EWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAWRLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAV
         WG YV+ LLSDG+  P+SGTD GDHPPITPM  ATE MVG DAWRLYQYVCQHF+G++S +CKY+RTK++ SI GE F+CTG  V  KGFT+IMPW AV
Subjt:  EWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAWRLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAV

Query:  NEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRS
        +EKKLP FLKG++IEV +V+LY+GNT+PPDYL+ESELISLMEKHGIGTDASI VHINNIGERNYVQVQ+GR++VPT LGITLIRGYQCIDPDLCLPDIRS
Subjt:  NEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRS

Query:  FIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALFEAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYK
        FIEQQIT VAKGQADH  VVQ+V+QQF++K+SYFV++I+HMDALFEAQFSPLA+SGRALSKCGKCLRYMK I++ P RL+CGTCEEVYYLPQ+G +KLYK
Subjt:  FIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALFEAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYK

Query:  ELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNW
        ELTCPLDNFEL+I+S+PGPEGKSFPLCPYCYNSPPFEGIDTL+GA+KT  +   +  G GMPC LCPHPTC+HS+  QGVCACPEC GTLVLDPV  P W
Subjt:  ELTCPLDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNW

Query:  KLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTPLEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGK
        KLNCN C+C+V LP+GAHRI TT+ +C ECDS IIE+DFNKKTTPLE GATL  GC+LCDE L SL+E+KHG+SF R RG RGRGRGRGRGRG GR   K
Subjt:  KLNCNKCNCLVFLPQGAHRIATTNEKCAECDSTIIEVDFNKKTTPLEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGK

Query:  LMDPKMSFRDF
         +DPKMSFRDF
Subjt:  LMDPKMSFRDF

AT5G63920.1 topoisomerase 3alpha

5.9e-113

37.03

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Query:  SVLMVAEKPSIALSIASALSHGQMSTRKGST---EVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHLS
        +VL VAEKPS+A S+A  LS G   TR+G +   ++ EFD    G      +TSVIGH+  ++F  R++ W + DP DL+QA V+K     K  I++ L 
Subjt:  SVLMVAEKPSIALSIASALSHGQMSTRKGST---EVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHLS

Query:  REARGCDCLVLWLDCDREGENICFEVIE-CTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKY-
         EAR  D LVLWLDCDREGENI FEV++ C     N +   + RA FS++ ++DI +A+ NL +PN+  A AVDARQEIDL++G SFTRFQT   + ++ 
Subjt:  REARGCDCLVLWLDCDREGENICFEVIE-CTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKY-

Query:  ----GNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSV-CPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQES-KVRPS
            G   SR+ISYGPCQ PTLGF V+R+ +I   +PE+FW++ C +  + G     +W RG LFD   A +  +  +E+  A V  +   +E  K  P 
Subjt:  ----GNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSV-CPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQES-KVRPS

Query:  GLNTVNLLKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSD----GYSKPRSGTDVGDHPPITPMSL
         LNT+ L K AS       +  M++AE LY  GFISYPRTE+ ++ S  D +  +    ++P WG Y + LL        +    G D   HPPI P   
Subjt:  GLNTVNLLKVASSALGYGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSD----GYSKPRSGTDVGDHPPITPMSL

Query:  AT-EDMVGRDAWRLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLS
        ++ E    RD   +Y+ V +H++  +S       T ++  IAGE F+ +G +++ K +  +  + +     +P + KGQ+     + L    T PP  L 
Subjt:  AT-EDMVGRDAWRLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSSVMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLS

Query:  ESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKY-S
        E++L+S M+K GIGTDA++  HI  + +R Y    A  R  PTNLG  L+ GY  +  +L  P++R+ +E  +  V+ G+     V++  LQQ K  +  
Subjt:  ESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKY-S

Query:  YFVKK---IDHMDALFE----AQFSPLAESGRALSKCGKC
          VKK   ++ M   FE       S    +G  + +C  C
Subjt:  YFVKK---IDHMDALFE----AQFSPLAESGRALSKCGKC

Sequences

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CDS sequence

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ATGGTCGCTTCCTCGGTTCTTATGGTGGCTGAGAAGCCTAGCATTGCGCTCTCGATTGCTTCTGCACTCTCGCACGGCCAAATGTCTACAAGAAAGGGTAGCACAGAGGT
ACATGAATTCGATGGGAGATTTCTTGGGCATCATGCCCATTACAAAGTGACATCGGTTATCGGACATGTTTTCAGTATAGATTTCCCTGCTAGATTTCAAGATTGGAAGG
CAACTGATCCTTTGGATCTTTTTCAAGCTTCAGTAATTAAGACAGAATCAAACCCAAAGGCTCACATACGTCAACATTTAAGTCGGGAAGCTCGTGGTTGTGATTGTTTG
GTTTTATGGTTGGATTGTGATCGTGAAGGAGAAAATATTTGTTTTGAAGTTATTGAATGCACTGGATTTGGTGGCAATGAATATAGGAAAAAAGTGTATCGGGCAAGGTT
TTCTTCCGTTACTGAAAAAGATATTCTGAAGGCTTTGGATAACCTTGTTGAACCTAATAGAAATGAGGCACTGGCTGTAGATGCTCGACAAGAGATAGATTTGAAAGTTG
GAGTATCTTTTACACGATTTCAGACTACATTTTTTCAGGGAAAATATGGGAACCTTGATTCCAGACTCATCTCCTATGGGCCATGCCAAACTCCCACGCTTGGGTTTTGT
GTACAGCGTCATTTGCAAATAACTACTTTTAAGCCAGAAAAATTTTGGTCTGTGTGCCCTTATATCATGCAAAATGGCTATGAACTTAATCTAGACTGGGAGCGTGGCAG
GCTATTTGACTGTGATGTTGCTACAATGTTTCAAAAGCGAGTAATGGAAGATGGAATTGCAGAAGTAACACAAATATCAGAGAAGCAAGAAAGCAAAGTTCGACCTTCTG
GACTAAATACAGTTAACCTTCTGAAGGTTGCTTCAAGCGCACTAGGATACGGACCTCAAATGGCAATGCAACTAGCTGAACGATTGTATACCCAAGGGTTCATCAGCTAT
CCACGTACAGAAAGTACGGCTTATCCTTCTTCATTTGACTTCAAAGGCACTCTACATTCCCTAGTGAAAAATCCAGAATGGGGTGATTATGTAAGGATGCTTCTATCCGA
TGGATACAGTAAGCCACGATCAGGAACTGATGTAGGTGATCATCCTCCTATTACTCCAATGTCTTTAGCAACTGAAGACATGGTGGGGAGAGATGCTTGGAGATTGTACC
AATACGTGTGTCAACACTTCATTGGGTCTCTATCATCTGACTGCAAGTATCTTAGGACGAAGATACAGTTTTCAATCGCTGGGGAAATATTCAATTGTACTGGGTCCAGT
GTTATGGTAAAAGGATTCACCTCCATTATGCCATGGTTGGCAGTAAATGAAAAAAAATTACCTCAGTTTCTGAAGGGACAGAAAATAGAAGTTGCAAAAGTGGATCTTTA
TCAGGGGAACACCTCGCCTCCTGATTATTTAAGTGAGAGTGAGTTAATTTCTCTCATGGAGAAGCATGGAATAGGCACGGATGCATCAATACCTGTACACATTAACAACA
TAGGCGAGCGCAACTATGTGCAGGTTCAAGCTGGGAGGAGGTTGGTTCCAACTAACTTGGGCATCACCTTAATCAGAGGTTATCAGTGTATTGATCCAGATCTCTGCTTA
CCAGATATTAGAAGTTTCATCGAGCAACAGATCACTTTTGTTGCCAAAGGTCAAGCAGATCATTTTAGTGTTGTGCAGAATGTACTGCAACAGTTCAAGCAAAAGTATAG
CTACTTCGTTAAGAAGATCGATCATATGGATGCTCTGTTTGAAGCACAATTTTCTCCTCTTGCGGAGTCGGGACGTGCTTTGAGCAAATGTGGCAAATGCCTACGTTATA
TGAAGTTTATTTCTTCCCAACCACAGCGCCTGTACTGTGGTACATGTGAGGAGGTTTATTATCTTCCTCAAAGGGGAGCAATAAAGCTGTACAAGGAACTTACATGCCCT
TTGGATAACTTTGAGCTCTTGATTTTTTCCTTACCTGGTCCAGAAGGCAAGTCATTTCCTCTTTGCCCATACTGCTACAATAGTCCTCCATTCGAGGGTATCGACACATT
ATATGGTGCTGCTAAAACCAACCCGAGTTCTGGAGCATCGAGCAAGGGAATGGGCATGCCATGCTTCCTATGCCCGCACCCAACATGTCGACATTCTTTAATAACCCAAG
GAGTTTGCGCTTGCCCGGAATGTAGCGGGACGCTTGTCCTAGATCCAGTGGGTGCACCCAACTGGAAACTCAACTGCAACAAATGCAATTGTCTTGTCTTCCTTCCTCAG
GGTGCTCATAGGATTGCCACCACAAACGAGAAGTGTGCTGAATGTGACTCTACAATTATAGAAGTGGACTTCAACAAGAAAACTACTCCATTGGAGGGTGGAGCTACATT
GTTTGTTGGGTGCATTCTTTGCGATGAATTTCTCCACTCCCTTCTGGAGATGAAGCATGGAAAATCATTTTTCAGAGGGAGAGGTTCTAGAGGAAGGGGACGGGGACGGG
GAAGGGGAAGAGGAAGAGGACGTAGTTCTGGGAAACTGATGGACCCGAAAATGAGTTTCCGAGATTTCTGA

mRNA sequence

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Protein sequence

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MVASSVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAHYKVTSVIGHVFSIDFPARFQDWKATDPLDLFQASVIKTESNPKAHIRQHLSREARGCDCL
VLWLDCDREGENICFEVIECTGFGGNEYRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVSFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFC
VQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGRLFDCDVATMFQKRVMEDGIAEVTQISEKQESKVRPSGLNTVNLLKVASSALGYGPQMAMQLAERLYTQGFISY
PRTESTAYPSSFDFKGTLHSLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMSLATEDMVGRDAWRLYQYVCQHFIGSLSSDCKYLRTKIQFSIAGEIFNCTGSS
VMVKGFTSIMPWLAVNEKKLPQFLKGQKIEVAKVDLYQGNTSPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCL
PDIRSFIEQQITFVAKGQADHFSVVQNVLQQFKQKYSYFVKKIDHMDALFEAQFSPLAESGRALSKCGKCLRYMKFISSQPQRLYCGTCEEVYYLPQRGAIKLYKELTCP
LDNFELLIFSLPGPEGKSFPLCPYCYNSPPFEGIDTLYGAAKTNPSSGASSKGMGMPCFLCPHPTCRHSLITQGVCACPECSGTLVLDPVGAPNWKLNCNKCNCLVFLPQ
GAHRIATTNEKCAECDSTIIEVDFNKKTTPLEGGATLFVGCILCDEFLHSLLEMKHGKSFFRGRGSRGRGRGRGRGRGRGRSSGKLMDPKMSFRDF

Carg24791 (gene) of Silver-seed gourd (SMH-JMG-627) v2 genome