CuGenDBv2

Gene ID	Carg25262
Organism	Cucurbita argyrosperma subsp. argyrosperma cv. SMH-JMG-627 (Silver-seed gourd (SMH-JMG-627) v2)
Description	sodium/hydrogen exchanger 8
Genome location	Carg_Chr04:17023568..17023783
RNA-Seq Expression	Carg25262
Synteny	Carg25262
Gene Ontology terms	GO:0051453 - regulation of intracellular pH (biological process) GO:0071805 - potassium ion transmembrane transport (biological process) GO:0098656 - anion transmembrane transport (biological process) GO:0098719 - sodium ion import across plasma membrane (biological process) GO:1902600 - proton transmembrane transport (biological process) GO:0005886 - plasma membrane (cellular component) GO:0016021 - integral component of membrane (cellular component) GO:0015385 - sodium:proton antiporter activity (molecular function) GO:0015386 - potassium:proton antiporter activity (molecular function)
InterPro domains	IPR018409 - Na+/H+ exchanger, isoform 8 IPR018422 - Cation/H+ exchanger, CPA1 family

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6601902.1 Sodium/hydrogen exchanger 7, partial [Cucurbita argyrosperma subsp. sororia]

1.0e-28

100

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Query:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
        MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
Subjt:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI

KAG7032600.1 Sodium/hydrogen exchanger 7, partial [Cucurbita argyrosperma subsp. argyrosperma]

1.1e-30

100

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Query:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSIGW
        MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSIGW
Subjt:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSIGW

XP_022955949.1 sodium/hydrogen exchanger 8 isoform X1 [Cucurbita moschata]

1.0e-28

100

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Query:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
        MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
Subjt:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI

XP_022989835.1 sodium/hydrogen exchanger 8 isoform X1 [Cucurbita maxima]

1.0e-28

100

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Query:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
        MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
Subjt:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI

XP_023525783.1 sodium/hydrogen exchanger 8 isoform X1 [Cucurbita pepo subsp. pepo]

1.0e-28

100

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Query:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
        MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
Subjt:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI

TrEMBL top hits

e value

%identity

Alignment

A0A5D3BDF1 Son of sevenless-like protein 1

5.5e-25

88.41

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Query:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
        MA VELL++F +R+LEEGAI SSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGI+LGSI
Subjt:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI

A0A6J1CX31 sodium/hydrogen exchanger 8-like isoform X1

3.2e-25

88.41

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Query:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
        MA VELL++F +R+LEEGA GSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGI+LGSI
Subjt:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI

A0A6J1CZ50 sodium/hydrogen exchanger 8-like isoform X2

3.2e-25

88.41

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Query:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
        MA VELL++F +R+LEEGA GSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGI+LGSI
Subjt:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI

A0A6J1GXP6 sodium/hydrogen exchanger 8 isoform X1

4.8e-29

100

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Query:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
        MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
Subjt:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI

A0A6J1JNG7 sodium/hydrogen exchanger 8 isoform X1

4.8e-29

100

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Query:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
        MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
Subjt:  MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI

SwissProt top hits

e value

%identity

Alignment

Q3YL57 Sodium/hydrogen exchanger 8

2.6e-11

62.71

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Query:  EGAIGSS------DWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
        E AI SS      D +P DAV+F G SLVLG ACR+L  GTRVPYTV LLV+GI LGS+
Subjt:  EGAIGSS------DWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI

Q9LKW9 Sodium/hydrogen exchanger 7

1.6e-13

67.19

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Query:  RELEEGAIGSS-------DWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
        R LEE    SS       + +P DAVLFVG+SLVLGIA RHLLRGTRVPYTVALLV+GI LGS+
Subjt:  RELEEGAIGSS-------DWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI

Arabidopsis top hits

e value

%identity

Alignment

AT1G14660.1 Na+/H+ exchanger 8

1.8e-12

62.71

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Query:  EGAIGSS------DWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
        E AI SS      D +P DAV+F G SLVLG ACR+L  GTRVPYTV LLV+GI LGS+
Subjt:  EGAIGSS------DWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI

AT1G14660.2 Na+/H+ exchanger 8

1.8e-12

62.71

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Query:  EGAIGSS------DWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
        E AI SS      D +P DAV+F G SLVLG ACR+L  GTRVPYTV LLV+GI LGS+
Subjt:  EGAIGSS------DWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI

AT2G01980.1 sodium proton exchanger, putative (NHX7) (SOS1)

1.1e-14

67.19

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Query:  RELEEGAIGSS-------DWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI
        R LEE    SS       + +P DAVLFVG+SLVLGIA RHLLRGTRVPYTVALLV+GI LGS+
Subjt:  RELEEGAIGSS-------DWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSI

Sequences

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CDS sequence

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ATGGCGGAAGTAGAATTGCTGGAAATGTTTACAAACCGAGAGCTGGAAGAAGGAGCCATTGGTTCGTCTGATTGGAATCCAACTGATGCTGTGCTGTTCGTTGGACTGAG
TTTGGTGCTTGGAATCGCTTGTAGACACTTACTGCGAGGCACCAGAGTTCCTTATACAGTTGCCTTGCTTGTTCTTGGCATAATTCTTGGATCCATTGGTTGGTGA

mRNA sequence

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Protein sequence

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MAEVELLEMFTNRELEEGAIGSSDWNPTDAVLFVGLSLVLGIACRHLLRGTRVPYTVALLVLGIILGSIGW

Carg25262 (gene) of Silver-seed gourd (SMH-JMG-627) v2 genome