CuGenDBv2

Gene ID	CcUC01G013090
Organism	Citrullus colocynthis (Watermelon (PI 537277) v1)
Description	NADPH--cytochrome P450 reductase
Genome location	CicolChr01:25127753..25129559
RNA-Seq Expression	CcUC01G013090
Synteny	CcUC01G013090
Gene Ontology terms	GO:0005789 - endoplasmic reticulum membrane (cellular component) GO:0005829 - cytosol (cellular component) GO:0016021 - integral component of membrane (cellular component) GO:0003958 - NADPH-hemoprotein reductase activity (molecular function) GO:0010181 - FMN binding (molecular function) GO:0050660 - flavin adenine dinucleotide binding (molecular function) GO:0050661 - NADP binding (molecular function)
InterPro domains	IPR017938 - Riboflavin synthase-like beta-barrel IPR029039 - Flavoprotein-like superfamily

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

TYK11826.1 NADPH--cytochrome P450 reductase 2 [Cucumis melo var. makuwa]

2.9e-67

95.45

Show/hide

Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        IAKVVDELLETQG KRLVKVGLGDDDQCIEDDF+AWRESLWPELDQLLRDEDDA TVTTPYTAAISEYRVVFHDPADV D+NKNWMNANGHAVHDAQHPF
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK
        RSNVVVRKELH PASDRSCTHLEFDISGSALK
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK

XP_008453604.1 PREDICTED: NADPH--cytochrome P450 reductase 2 [Cucumis melo]

2.9e-67

95.45

Show/hide

Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        IAKVVDELLETQG KRLVKVGLGDDDQCIEDDF+AWRESLWPELDQLLRDEDDA TVTTPYTAAISEYRVVFHDPADV D+NKNWMNANGHAVHDAQHPF
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK
        RSNVVVRKELH PASDRSCTHLEFDISGSALK
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK

XP_022987440.1 NADPH--cytochrome P450 reductase-like [Cucurbita maxima]

8.6e-67

96.21

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Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        IAKVVDELLETQG KRLVKVGLGDDDQCIEDD AAWRE LWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPA VADENKNWMNANGHAVHDAQHP 
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK
        RSNVVVRKELHMPASDRSCTHLEFDISGSALK
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK

XP_023516288.1 NADPH--cytochrome P450 reductase-like [Cucurbita pepo subsp. pepo]

8.6e-67

96.21

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Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        IAKVVDELLETQG KRLVKVGLGDDDQCIEDD AAWRE LWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPA VADENKNWMNANGHAVHDAQHP 
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK
        RSNVVVRKELHMPASDRSCTHLEFDISGSALK
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK

XP_038879587.1 NADPH--cytochrome P450 reductase 1-like [Benincasa hispida]

3.5e-68

96.97

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Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        IAKVVDELLETQG KRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADV D+NKNWMNANGHAVHDAQHPF
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK
        RSNVVVRKELH PASDRSCTHLEFDISGSALK
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LXA1 NADPH--cytochrome P450 reductase

1.3e-65

93.18

Show/hide

Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        IAKVVDELLETQG KRLVKVGLGDDDQCIEDDF+AWRESLWPELDQLLRDEDDA TVTTPYTAAISEYRVVFHDP+DV D+ KNWMNANGHAVHDAQHPF
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK
        RSNVVVRKELH PASDRSCTHLEFDIS SALK
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK

A0A1S3BXG0 NADPH--cytochrome P450 reductase

1.4e-67

95.45

Show/hide

Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        IAKVVDELLETQG KRLVKVGLGDDDQCIEDDF+AWRESLWPELDQLLRDEDDA TVTTPYTAAISEYRVVFHDPADV D+NKNWMNANGHAVHDAQHPF
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK
        RSNVVVRKELH PASDRSCTHLEFDISGSALK
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK

A0A5D3CN13 NADPH--cytochrome P450 reductase

1.4e-67

95.45

Show/hide

Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        IAKVVDELLETQG KRLVKVGLGDDDQCIEDDF+AWRESLWPELDQLLRDEDDA TVTTPYTAAISEYRVVFHDPADV D+NKNWMNANGHAVHDAQHPF
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK
        RSNVVVRKELH PASDRSCTHLEFDISGSALK
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK

A0A6J1E2A5 NADPH--cytochrome P450 reductase

1.6e-66

95.45

Show/hide

Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        IAKVVDELLETQG KRLVKVGLGDDDQCIEDD AAWRE LWPELDQLLRDEDDAT VTTPYTAAISEYRVVFHDPA VADENKNWMNANGHAVHDAQHP 
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK
        RSNVVVRKELHMPASDRSCTHLEFDISGSALK
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK

A0A6J1JGV7 NADPH--cytochrome P450 reductase

4.1e-67

96.21

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Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        IAKVVDELLETQG KRLVKVGLGDDDQCIEDD AAWRE LWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPA VADENKNWMNANGHAVHDAQHP 
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK
        RSNVVVRKELHMPASDRSCTHLEFDISGSALK
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSALK

SwissProt top hits

e value

%identity

Alignment

A0A2U1LIM9 NADPH--cytochrome P450 reductase 1

2.9e-49

73.28

Show/hide

Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        IAKVVDE L  QGAKRLV VG+GDDDQCIEDDF AW+E +WPELDQLLRDEDD T+V TPYTAA++EYRVVFHD  +  D+++     NGHAVHDAQHP 
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL
        RSNV V+KELH P SDRSCTHLEFDIS + L
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL

C5YJG8 NADPH--cytochrome P450 reductase

1.4e-48

71.76

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Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        +AKVVDE+L  QG KRLV VGLGDDDQCIEDDF AW+E+LWPELD+LLRDE+DA+T TT YTAAI EYRV F  P + A   +N+  ANGHAVHDAQHP 
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL
        ++NV VR+ELH PASDRSCTHLEFDI+G+ L
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL

Q0J705 NADPH--cytochrome P450 reductase 2

2.4e-48

72.52

Show/hide

Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        +AKVVDELL  QG KRLV VGLGDDDQCIEDDF AW+E+LWPELDQLLRDE+D +T TT YTAAI EYRV F  P + A   +N+  ANG+AVHDAQHP 
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL
        R+NV VR+ELH PASDRSCTHLEFDI+G+ L
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL

Q7X7K8 NADPH--cytochrome P450 reductase 1

3.1e-51

73.28

Show/hide

Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        +AKVVDELLE QG KRLV VGLGDDDQCIEDDF AW+E +WPELDQLLRDEDD T  +TPYTAAI EYR+VF D +DV+ ++K+W  ANG  V D  HP 
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL
        RSNV VRKELH PASDRSC HLEFDISG+ L
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL

Q9SUM3 NADPH--cytochrome P450 reductase 2

1.5e-45

65.65

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Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        +AKVVD++L  QGA+RLV+VGLGDDDQCIEDDF AWRE+LWPELD +LR+E D T V TPYTAA+ EYRV  HD  D    + N  N NG+ V DAQHP+
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL
        ++NV V++ELH P SDRSC HLEFDI+GS L
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL

Arabidopsis top hits

e value

%identity

Alignment

AT4G24520.1 P450 reductase 1

3.4e-37

59.54

Show/hide

Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        I  V+DE L  +GAKRL++VGLGDDDQ IEDDF AW+ESLW ELD+LL+DEDD  +V TPYTA I EYRVV HDP     ++     ANG+   D  HP 
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL
        R +V V+KELH   SDRSC HLEFDIS + +
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL

AT4G24520.2 P450 reductase 1

3.4e-37

59.54

Show/hide

Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        I  V+DE L  +GAKRL++VGLGDDDQ IEDDF AW+ESLW ELD+LL+DEDD  +V TPYTA I EYRVV HDP     ++     ANG+   D  HP 
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL
        R +V V+KELH   SDRSC HLEFDIS + +
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL

AT4G30210.1 P450 reductase 2

1.0e-46

65.65

Show/hide

Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        +AKVVD++L  QGA+RLV+VGLGDDDQCIEDDF AWRE+LWPELD +LR+E D T V TPYTAA+ EYRV  HD  D    + N  N NG+ V DAQHP+
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL
        ++NV V++ELH P SDRSC HLEFDI+GS L
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL

AT4G30210.2 P450 reductase 2

1.0e-46

65.65

Show/hide

Query:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF
        +AKVVD++L  QGA+RLV+VGLGDDDQCIEDDF AWRE+LWPELD +LR+E D T V TPYTAA+ EYRV  HD  D    + N  N NG+ V DAQHP+
Subjt:  IAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHDAQHPF

Query:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL
        ++NV V++ELH P SDRSC HLEFDI+GS L
Subjt:  RSNVVVRKELHMPASDRSCTHLEFDISGSAL

Sequences

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CDS sequence

Show/hide CDS sequence

ATGGGGAATTGGGGAATGATATCTTTCCGCGTGACTGAGATTAGTATTGCAAAAGTGGTAGATGAGCTGCTTGAAACTCAGGGGGCGAAGCGCCTTGTAAAAGTTGGTCT
GGGAGATGATGACCAGTGCATAGAGGATGACTTCGCTGCTTGGCGAGAATCATTGTGGCCTGAGTTGGATCAATTGCTTCGGGATGAGGATGATGCAACAACAGTGACCA
CACCTTACACAGCTGCCATATCAGAATATCGAGTGGTATTCCATGATCCTGCTGATGTAGCTGATGAGAACAAGAACTGGATGAATGCAAATGGTCATGCTGTACATGAT
GCTCAACATCCATTCAGATCGAATGTGGTTGTGAGAAAGGAGCTCCATATGCCTGCATCTGATCGTTCTTGTACTCATCTAGAGTTCGATATTTCTGGGTCTGCACTCAA
GTAA

mRNA sequence

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Protein sequence

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MGNWGMISFRVTEISIAKVVDELLETQGAKRLVKVGLGDDDQCIEDDFAAWRESLWPELDQLLRDEDDATTVTTPYTAAISEYRVVFHDPADVADENKNWMNANGHAVHD
AQHPFRSNVVVRKELHMPASDRSCTHLEFDISGSALK

CcUC01G013090 (gene) of Watermelon (PI 537277) v1 genome