CuGenDBv2

Gene ID	CcUC04G067580
Organism	Citrullus colocynthis (Watermelon (PI 537277) v1)
Description	S-adenosylmethionine synthase
Genome location	CicolChr04:24309279..24309680
RNA-Seq Expression	CcUC04G067580
Synteny	CcUC04G067580
Gene Ontology terms	GO:0006556 - S-adenosylmethionine biosynthetic process (biological process) GO:0006730 - one-carbon metabolic process (biological process) GO:0005829 - cytosol (cellular component) GO:0004478 - methionine adenosyltransferase activity (molecular function) GO:0005524 - ATP binding (molecular function) GO:0046872 - metal ion binding (molecular function)
InterPro domains	IPR002133 - S-adenosylmethionine synthetase IPR022628 - S-adenosylmethionine synthetase, N-terminal IPR022636 - S-adenosylmethionine synthetase superfamily

Homology

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GenBank top hits

e value

%identity

Alignment

QHO39172.1 S-adenosylmethionine synthase [Arachis hypogaea]

1.9e-44

73.81

Show/hide

Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        METFLFT KSVNEGHPDK+CDQVSDAIL  CLEQD ES VACET TK+NMVMVF EIT KANVNYEKIV++TC GIGF+S D+GLDAD+C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GH+TKKPE+IGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

QHO50060.1 S-adenosylmethionine synthase [Arachis hypogaea]

1.9e-44

73.02

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Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        METFLFT +SVNEGHPDK+CDQVSDAIL  CLEQD ES VACET TK+NMVMVF EIT KANVNYEKIV++TC GIGF+S+D+GLDAD+C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GH+TKKPE+IGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

RYR77345.1 hypothetical protein Ahy_A01g001774 isoform A [Arachis hypogaea]

1.9e-44

73.02

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Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        METFLFT +SVNEGHPDK+CDQVSDAIL  CLEQD ES VACET TK+NMVMVF EIT KANVNYEKIV++TC GIGF+S+D+GLDAD+C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GH+TKKPE+IGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

RYR77347.1 hypothetical protein Ahy_A01g001774 isoform C [Arachis hypogaea]

1.9e-44

73.02

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Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        METFLFT +SVNEGHPDK+CDQVSDAIL  CLEQD ES VACET TK+NMVMVF EIT KANVNYEKIV++TC GIGF+S+D+GLDAD+C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GH+TKKPE+IGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

XP_025604425.1 S-adenosylmethionine synthase 3-like [Arachis hypogaea]

1.9e-44

73.02

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Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        METFLFT +SVNEGHPDK+CDQVSDAIL  CLEQD ES VACET TK+NMVMVF EIT KANVNYEKIV++TC GIGF+S+D+GLDAD+C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GH+TKKPE+IGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

TrEMBL top hits

e value

%identity

Alignment

A0A1J7ID88 S-adenosylmethionine synthase

1.2e-44

74.6

Show/hide

Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        METFLFT +SVNEGHPDK+CDQVSDAIL  CLEQD ES VACET TK+NMVMVF EIT KANVNYEKIV++TC GIGFIS D+GLDAD+C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GH+TKKPEDIGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

A0A1S3TR49 S-adenosylmethionine synthase

2.0e-44

73.81

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Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        METFLFT +SVNEGHPDKLCDQVSDAIL  CLEQD +S VACET TK+NMVMVF EIT KANVNYEKIV++TC GIGF+S D+GLDAD+C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GHLTKKPE+IGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

A0A445EPE5 Uncharacterized protein

9.0e-45

73.02

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Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        METFLFT +SVNEGHPDK+CDQVSDAIL  CLEQD ES VACET TK+NMVMVF EIT KANVNYEKIV++TC GIGF+S+D+GLDAD+C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GH+TKKPE+IGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

A0A445EPF3 Uncharacterized protein

9.0e-45

73.02

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Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        METFLFT +SVNEGHPDK+CDQVSDAIL  CLEQD ES VACET TK+NMVMVF EIT KANVNYEKIV++TC GIGF+S+D+GLDAD+C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GH+TKKPE+IGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

A0A445EPP0 Uncharacterized protein

9.0e-45

73.02

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Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        METFLFT +SVNEGHPDK+CDQVSDAIL  CLEQD ES VACET TK+NMVMVF EIT KANVNYEKIV++TC GIGF+S+D+GLDAD+C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GH+TKKPE+IGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

SwissProt top hits

e value

%identity

Alignment

A7PQS0 S-adenosylmethionine synthase 1

2.7e-46

73.02

Show/hide

Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        M+TFLFT +SVNEGHPDKLCDQVSDAIL  CLEQD ES VACET TK+NMVMVF EIT KA VNYEKIV++TC GIGF+S D+GLDAD+C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GHLTKKPE+IGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

A9NUH8 S-adenosylmethionine synthase 1

4.6e-46

70.63

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Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        M+TFLFT +SVNEGHPDKLCDQ+SDAIL  CLEQD ES VACET TK+NMVM+F EIT KAN++YEKIV++TC GIGF+S D+GLDAD+C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GHLTKKPE+IGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

P43282 S-adenosylmethionine synthase 3

4.6e-46

73.02

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Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        METFLFT +SVNEGHPDKLCDQVSDAIL  CLEQD ES VACET TK+NMVMVF EIT KA V+YEKIV++TC GIGF+S D+GLDAD+C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GHLTKKPE+IGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

Q96553 S-adenosylmethionine synthase 3

6.0e-46

73.81

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Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        METFLFT +SVNEGHPDKLCDQVSDAIL  CLEQD ES VACET TK+NMVMVF EIT KA VNYEKIV++TC GIGF S D+GLDAD+C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GHLTKKPE+IGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

Q9M7K8 S-adenosylmethionine synthase 1

1.3e-45

73.02

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Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        METFLFT +SVNEGHPDKLCDQVSDAIL  CLEQD ES VACET TK+NMVMVF EIT KA V+YEKIV++TC GIGF S D+GLDAD+C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GHLTKKPE+IGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

Arabidopsis top hits

e value

%identity

Alignment

AT2G36880.1 methionine adenosyltransferase 3

1.6e-46

73.02

Show/hide

Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        METFLFT +SVNEGHPDKLCDQ+SDAIL  CLEQD ES VACET TK+NMVMVF EIT  A V+YEKIV++TC  IGFIS D+GLDAD CN  +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GHLTKKPEDIGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

AT2G36880.2 methionine adenosyltransferase 3

1.6e-46

73.02

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Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        METFLFT +SVNEGHPDKLCDQ+SDAIL  CLEQD ES VACET TK+NMVMVF EIT  A V+YEKIV++TC  IGFIS D+GLDAD CN  +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GHLTKKPEDIGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

AT3G17390.1 S-adenosylmethionine synthetase family protein

1.1e-45

69.84

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Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        ME+FLFT +SVNEGHPDKLCDQ+SDAIL  CLEQD ES VACET TK+NMVMVF EIT KANV+YE+IV+ TC  IGF+S D+GLDAD+C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GHLTKKPE++GAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

AT4G01850.1 S-adenosylmethionine synthetase 2

4.0e-45

69.05

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Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        METFLFT +SVNEGHPDKLCDQ+SDA+L  CLEQD +S VACET TK+NMVMVF EIT KA ++YEKIV++TC  IGFIS D+GLDAD C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GH TK+PEDIGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

AT4G01850.2 S-adenosylmethionine synthetase 2

4.0e-45

69.05

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Query:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI
        METFLFT +SVNEGHPDKLCDQ+SDA+L  CLEQD +S VACET TK+NMVMVF EIT KA ++YEKIV++TC  IGFIS D+GLDAD C   +NIEQ+ 
Subjt:  METFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCN--MNIEQRI

Query:  PEPT----GHLTKKPEDIGAGDLGHM
        P+      GH TK+PEDIGAGD GHM
Subjt:  PEPT----GHLTKKPEDIGAGDLGHM

Sequences

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CDS sequence

Show/hide CDS sequence

ATGATGGAAACCTTCCTCTTCACTCATAAGTCTGTCAACGAGGGCCATCCCGACAAGCTTTGCGACCAAGTTTCCGATGCTATCCTCCACACTTGTCTTGAACAAGATTC
TGAGAGCAATGTCGCTTGTGAAACCTACACCAAATCCAACATGGTCATGGTGTTTGATGAGATAACAATCAAGGCTAATGTCAACTATGAGAAAATAGTTCAAAATACTT
GCGACGGAATTGGATTTATCTCTATTGATATCGGTCTTGATGCAGACGACTGCAACATGAATATTGAACAACGAATCCCAGAGCCGACTGGACACTTGACCAAGAAACCT
GAGGATATTGGAGCTGGTGATCTAGGCCACATGAGTTCTCACCCATGTCCTTGCTACAAAACTTGGTGCTAA

mRNA sequence

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Protein sequence

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MMETFLFTHKSVNEGHPDKLCDQVSDAILHTCLEQDSESNVACETYTKSNMVMVFDEITIKANVNYEKIVQNTCDGIGFISIDIGLDADDCNMNIEQRIPEPTGHLTKKP
EDIGAGDLGHMSSHPCPCYKTWC

CcUC04G067580 (gene) of Watermelon (PI 537277) v1 genome