CuGenDBv2

Gene ID	CcUC10G196220
Organism	Citrullus colocynthis (Watermelon (PI 537277) v1)
Description	PMEI domain-containing protein
Genome location	CicolChr10:22136258..22136806
RNA-Seq Expression	CcUC10G196220
Synteny	CcUC10G196220
Gene Ontology terms	GO:0043086 - negative regulation of catalytic activity (biological process) GO:0030599 - pectinesterase activity (molecular function) GO:0046910 - pectinesterase inhibitor activity (molecular function)
InterPro domains	IPR006501 - Pectinesterase inhibitor domain IPR035513 - Invertase/pectin methylesterase inhibitor domain superfamily

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0044390.1 putative invertase inhibitor [Cucumis melo var. makuwa]

1.3e-67

82.32

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Query:  MAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQGLFDCLDAYLNASQ
        MA QRLDAA  A +EG+  IE MCAQT+YKDLC+TSLTSDPNSFPADK+GLALVALRLASSNASDISESIKVM N+TS NEPAVQQGLFDCLD YL+ASQ
Subjt:  MAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQGLFDCLDAYLNASQ

Query:  QLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGTKPTVLTPKNEVFIKLCEIAMSISKIAE
        QLD SIAAIIAKAYGDVEKWV+AA+AD RTCE SF TKP+VLTP+NE FIKLC+IA+SIS+IAE
Subjt:  QLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGTKPTVLTPKNEVFIKLCEIAMSISKIAE

KAG6581280.1 Pectinesterase inhibitor, partial [Cucurbita argyrosperma subsp. sororia]

1.6e-62

69.95

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Query:  MKFVSAILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQ
        MKF+SAI++VL LCMA +R DA RP  EEG+ +IE MC+QT +K+LC+ SLTSDPNS+PADK GLALVALR ASSNASDISESIKVMFND++L++P VQ+
Subjt:  MKFVSAILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQ

Query:  GLFDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFG-TKPTVLTPKNEVFIKLCEIAMSISKIAEGEGN
         L DCLD YL+ASQQLD SIAA+  KAYGD+EKWVN AI D RTC    G  +P +LT +NEVFIKLCEIA++ISKIA+GEGN
Subjt:  GLFDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFG-TKPTVLTPKNEVFIKLCEIAMSISKIAEGEGN

XP_004152360.2 cell wall / vacuolar inhibitor of fructosidase 2 [Cucumis sativus]

3.9e-69

79.89

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Query:  MKFVSAILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSL-NEPAVQ
        MKF SAILLVL LCMA QRLDAA  A+EEGL MI+ MCAQT+YKDLCITSLTSDPNSFPADK+GLALVALRLASSNASDISESIKVM N+TS  NEP VQ
Subjt:  MKFVSAILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSL-NEPAVQ

Query:  QGLFDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGTKPTVLTPKNEVFIKLCEIAMSISKIAE
        Q LFDCLD YL ASQQLD SIAAIIAKAYGDV++WV  A+ + RTCE+SF TKP+VLTP+NE FIKLC+IA+SI+KIAE
Subjt:  QGLFDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGTKPTVLTPKNEVFIKLCEIAMSISKIAE

XP_022934353.1 pectinesterase inhibitor-like [Cucurbita moschata]

4.2e-63

70.49

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Query:  MKFVSAILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQ
        MKFVSAI++VL LCMA +R DA RP  EEG+ +IE MC+QT +K+LC+ SLTSDPNS+PADK GLALVALR ASSNASDISESIKVMFND++L++P VQ+
Subjt:  MKFVSAILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQ

Query:  GLFDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGT-KPTVLTPKNEVFIKLCEIAMSISKIAEGEGN
         L DCLD YL+ASQQLD SIAA+  KAYGD+EKWVN AI D RTC    G+ +P +LT +NEVFIKLCEIA++ISKIA+GEGN
Subjt:  GLFDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGT-KPTVLTPKNEVFIKLCEIAMSISKIAEGEGN

XP_038906317.1 cell wall / vacuolar inhibitor of fructosidase 2-like [Benincasa hispida]

7.1e-71

78.69

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Query:  MKFVSAILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQ
        MKFVSAIL VL L M  QRLDAA PA E+GL MI+HMCAQT+YKDLC+ SLTSDPNSFPADK+GLALVALR ASSNASDISESIKVM NDTSLN+P+VQQ
Subjt:  MKFVSAILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQ

Query:  GLFDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGTKPTVLTPKNEVFIKLCEIAMSISKIAE-GEGN
        GLFDCLD YL+ASQQLD +IAAI+ KAYGDVEKWV+AAIA  RTCE  F TKP++L PKN+VFIKLCEIA+SISK+A+  EGN
Subjt:  GLFDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGTKPTVLTPKNEVFIKLCEIAMSISKIAE-GEGN

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KY96 PMEI domain-containing protein

1.9e-69

79.89

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Query:  MKFVSAILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSL-NEPAVQ
        MKF SAILLVL LCMA QRLDAA  A+EEGL MI+ MCAQT+YKDLCITSLTSDPNSFPADK+GLALVALRLASSNASDISESIKVM N+TS  NEP VQ
Subjt:  MKFVSAILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSL-NEPAVQ

Query:  QGLFDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGTKPTVLTPKNEVFIKLCEIAMSISKIAE
        Q LFDCLD YL ASQQLD SIAAIIAKAYGDV++WV  A+ + RTCE+SF TKP+VLTP+NE FIKLC+IA+SI+KIAE
Subjt:  QGLFDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGTKPTVLTPKNEVFIKLCEIAMSISKIAE

A0A5D3E196 Putative invertase inhibitor

6.1e-68

82.32

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Query:  MAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQGLFDCLDAYLNASQ
        MA QRLDAA  A +EG+  IE MCAQT+YKDLC+TSLTSDPNSFPADK+GLALVALRLASSNASDISESIKVM N+TS NEPAVQQGLFDCLD YL+ASQ
Subjt:  MAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQGLFDCLDAYLNASQ

Query:  QLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGTKPTVLTPKNEVFIKLCEIAMSISKIAE
        QLD SIAAIIAKAYGDVEKWV+AA+AD RTCE SF TKP+VLTP+NE FIKLC+IA+SIS+IAE
Subjt:  QLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGTKPTVLTPKNEVFIKLCEIAMSISKIAE

A0A6J1DPW6 pectinesterase inhibitor-like

1.6e-52

64.77

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Query:  AILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSL-NEPAVQQGLFD
        A+L+V++L +A    +A RP K + + +IE  C+QT +  LC++SL SDPNSFPADK GLALVALRL SSNASDISE IKVM NDT L ++P VQQGL+D
Subjt:  AILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSL-NEPAVQQGLFD

Query:  CLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGTKPTVLTPKNEVFIKLCEIAMSISKIAEGE
        CLD YL+ASQQLD SIAA++ KAYGDV+KWVNAA+A  RTCEASF  KP+VLTP+N+ FIKLC+ A++I+ IAE E
Subjt:  CLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGTKPTVLTPKNEVFIKLCEIAMSISKIAEGE

A0A6J1F7F2 pectinesterase inhibitor-like

2.0e-63

70.49

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Query:  MKFVSAILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQ
        MKFVSAI++VL LCMA +R DA RP  EEG+ +IE MC+QT +K+LC+ SLTSDPNS+PADK GLALVALR ASSNASDISESIKVMFND++L++P VQ+
Subjt:  MKFVSAILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQ

Query:  GLFDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGT-KPTVLTPKNEVFIKLCEIAMSISKIAEGEGN
         L DCLD YL+ASQQLD SIAA+  KAYGD+EKWVN AI D RTC    G+ +P +LT +NEVFIKLCEIA++ISKIA+GEGN
Subjt:  GLFDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGT-KPTVLTPKNEVFIKLCEIAMSISKIAEGEGN

A0A6J1J9E7 pectinesterase inhibitor-like

1.4e-61

67.76

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Query:  MKFVSAILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQ
        MKF+SAI+++L LCMA +R DA RP  EEG+ +IE MC+QT +K+LC+ SLTSDPNS+PADK GLALVALR ASSNASDISESIKVMFND++L++P VQ+
Subjt:  MKFVSAILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQ

Query:  GLFDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGT-KPTVLTPKNEVFIKLCEIAMSISKIAEGEGN
         L DCLD YL+ASQQLD SIAA+  KAYGD+EKWVN A+ D RTC    G+ +P +LT +N+VFIKLCEIA++ISKIA+GE N
Subjt:  GLFDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGT-KPTVLTPKNEVFIKLCEIAMSISKIAEGEGN

SwissProt top hits

e value

%identity

Alignment

P83326 Pectinesterase inhibitor

1.1e-10

27.22

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Query:  FVSAILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQGL
        FVS +L++L++    Q     RP+ +    +I  +C +T    LC+ +L SDP S   D  GL   ++ +A ++A   S+ I  + N  +  +P ++   
Subjt:  FVSAILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQGL

Query:  FDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGTKPTVLTPKNEVFIK---LCEIAMSISKIAEG
          C + Y +A   L  +   + +  Y  +  + +AA   A TCE SF   P + T  ++  +K   LC+I + IS +  G
Subjt:  FDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGTKPTVLTPKNEVFIK---LCEIAMSISKIAEG

Q0J8J8 Pectinesterase inhibitor 28

4.3e-10

27.5

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Query:  PAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDT------SLNEPAVQQGLFDCLDAYLNASQQLDA
        P   +   ++   C  T Y D+C+++L +DP+S  AD  GL+ +A+ +A++NAS  +++   + N T      +  +  VQ  L  C   Y +A   L A
Subjt:  PAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDT------SLNEPAVQQGLFDCLDAYLNASQQLDA

Query:  SIAAIIAKAYGDVEKWVNAAIADARTCEASF-----GTKPTVLTPKNEVFIKLCEIAMSI
        +  ++  + Y      V+A     + C+A F     G  P  L  + E   KLC +A+ I
Subjt:  SIAAIIAKAYGDVEKWVNAAIADARTCEASF-----GTKPTVLTPKNEVFIKLCEIAMSI

Arabidopsis top hits

e value

%identity

Alignment

AT1G55770.1 Plant invertase/pectin methylesterase inhibitor superfamily protein

3.2e-21

38.26

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Query:  MIEHMCAQTDYKDLCITSLTSDPNS--FPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQGLFDCLDAYLNASQQLDASIAAIIAKAYGD
        MI  +C  +D  +LC++S+TS P S  F      + ++A+  AS+NAS  S  IK   ++  L EPA++  L DC   Y +A +QLD SI+A++A A+ D
Subjt:  MIEHMCAQTDYKDLCITSLTSDPNS--FPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQGLFDCLDAYLNASQQLDASIAAIIAKAYGD

Query:  VEKWVNAAIADARTCEASFGTK---PTVLTPKNEVFIKLCEIAMSISKI
        V+ W++AAI+   +C ++ G++      L+ +NEVF+KLC+ A+ I+K+
Subjt:  VEKWVNAAIADARTCEASFGTK---PTVLTPKNEVFIKLCEIAMSISKI

AT4G02250.1 Plant invertase/pectin methylesterase inhibitor superfamily protein

4.4e-18

39.71

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Query:  KDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQGLFDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADAR
        K  C+ SLTS P +  A    L ++AL +ASSNASD S  IK      +L EPA++  L DC   YL+A  QLD S+AA++  ++ DV+ W+N AI+D  
Subjt:  KDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQGLFDCLDAYLNASQQLDASIAAIIAKAYGDVEKWVNAAIADAR

Query:  TCEASFGTK---PTVLTPKNEVFIKLCEIAMSISKI
         CE +   +      L  +N   +KLC+ A+ I+ I
Subjt:  TCEASFGTK---PTVLTPKNEVFIKLCEIAMSISKI

Sequences

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CDS sequence

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ATGAAATTTGTCTCAGCCATTTTATTGGTCCTCTACCTTTGCATGGCGGTTCAGCGCCTTGACGCTGCCCGCCCGGCGAAGGAGGAGGGACTCCGCATGATCGAGCATAT
GTGTGCTCAAACTGACTACAAAGACCTTTGCATCACCTCGCTGACTTCCGACCCCAATAGCTTCCCCGCCGACAAGCTGGGGCTAGCCTTGGTTGCCCTCCGCCTCGCCT
CTTCCAATGCCTCTGACATATCAGAGAGTATCAAGGTGATGTTCAACGACACGAGCTTAAACGAGCCGGCAGTACAACAGGGCCTCTTTGATTGCCTTGATGCGTATCTG
AATGCATCGCAACAACTTGACGCCTCCATTGCTGCAATTATAGCGAAGGCCTATGGCGACGTCGAGAAATGGGTCAATGCGGCGATTGCTGATGCGCGCACGTGCGAGGC
TTCGTTCGGAACGAAGCCGACAGTGTTGACGCCGAAGAATGAAGTGTTTATTAAGCTATGTGAAATTGCAATGTCCATCTCCAAGATTGCGGAAGGAGAAGGAAATTAA

mRNA sequence

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Protein sequence

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MKFVSAILLVLYLCMAVQRLDAARPAKEEGLRMIEHMCAQTDYKDLCITSLTSDPNSFPADKLGLALVALRLASSNASDISESIKVMFNDTSLNEPAVQQGLFDCLDAYL
NASQQLDASIAAIIAKAYGDVEKWVNAAIADARTCEASFGTKPTVLTPKNEVFIKLCEIAMSISKIAEGEGN

CcUC10G196220 (gene) of Watermelon (PI 537277) v1 genome