CuGenDBv2

Gene ID	Chy4G079640
Organism	Cucumis hystrix (Cucumber (hystrix) v1)
Description	DNA topoisomerase 2
Genome location	chrH04:18984576..18991254
RNA-Seq Expression	Chy4G079640
Synteny	Chy4G079640
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0043231 - intracellular membrane-bounded organelle (cellular component) GO:0003677 - DNA binding (molecular function) GO:0046872 - metal ion binding (molecular function) GO:0005524 - ATP binding (molecular function) GO:0003918 - DNA topoisomerase type II (ATP-hydrolyzing) activity (molecular function)
InterPro domains	IPR013506 - DNA topoisomerase, type IIA, subunit B, domain 2 IPR036890 - Histidine kinase/HSP90-like ATPase superfamily IPR034157 - DNA topoisomerase 2, TOPRIM domain IPR031660 - C-terminal associated domain of TOPRIM IPR020568 - Ribosomal protein S5 domain 2-type fold IPR018522 - DNA topoisomerase, type IIA, conserved site IPR014721 - Ribosomal protein S5 domain 2-type fold, subgroup IPR013760 - DNA topoisomerase, type IIA-like domain superfamily IPR013759 - DNA topoisomerase, type IIA, subunit B, C-terminal IPR013758 - DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta IPR013757 - Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily IPR006171 - TOPRIM domain IPR003594 - Histidine kinase/HSP90-like ATPase IPR002205 - DNA topoisomerase, type IIA, subunit A/C-terminal IPR001241 - DNA topoisomerase, type IIA IPR001154 - DNA topoisomerase II, eukaryotic-type

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0048368.1 DNA topoisomerase 2 [Cucumis melo var. makuwa]

0.0

96.72

Show/hide

Query:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MV+EKKRPLQNSN ANVDSNP GPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPV+SFQDYVDLYLKSA S QAEPPKRYHIKPNERWEIVV
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVK+YLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQT  LIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRML+GETMLPMDPWYRGFSGTIEKTATKEGGTTYT+S
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDK  EKAAKDPFIEQADHHSDD+IVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPK
        TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLD LEKELDE+DRNDAQTMELRKQQR+K N DLKPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPK

Query:  ISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAMETEV
        ISRNAPKAPRN KKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAV D+D+DDEVLELKDRLAAYKIESSPEPS+VSAMETEV
Subjt:  ISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAMETEV

Query:  QEVQQAAKKKEPSKRAPAKKKTTAKSAQISISDD--DEDFEIKEVDPPAAKKGGGR---KAAAANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEKK
        QEVQ AAKKKEPSKRAPAKKKTTAKSAQISISDD  D+DFEIKEVDP AAKKGGGR   KAAAANGKTTK PAAG KLGQKLITQMLEPAENSGISPEKK
Subjt:  QEVQQAAKKKEPSKRAPAKKKTTAKSAQISISDD--DEDFEIKEVDPPAAKKGGGR---KAAAANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEKK

Query:  VRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEEV---QPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDEASLDED
        VRKIRASPFNKKSGSLLGR I EEEEED  +DEGK+MGSASSET+EEV   QPA GRSRRANRTQVRYVLSDSD E  SQDSDFDEDEASLDED
Subjt:  VRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEEV---QPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDEASLDED

XP_008461811.1 PREDICTED: DNA topoisomerase 2 [Cucumis melo]

0.0

96.72

Show/hide

Query:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MV+EKKRPLQNSN ANVDSNP GPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPV+SFQDYVDLYLKSA S QAEPPKRYHIKPNERWEIVV
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVK+YLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQT  LIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRML+GETMLPMDPWYRGFSGTIEKTATKEGGTTYT+S
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDK  EKAAKDPFIEQADHHSDD+IVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPK
        TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLD LEKELDE+DRNDAQTMELRKQQR+K N DLKPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPK

Query:  ISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAMETEV
        ISRNAPKAPRN KKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAV D+D+DDEVLELKDRLAAYKIESSPEPS+VSAMETEV
Subjt:  ISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAMETEV

Query:  QEVQQAAKKKEPSKRAPAKKKTTAKSAQISISDD--DEDFEIKEVDPPAAKKGGGR---KAAAANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEKK
        QEVQ AAKKKEPSKRAPAKKKTTAKSAQISISDD  D+DFEIKEVDP AAKKGGGR   KAAAANGKTTK PAAG KLGQKLITQMLEPAENSGISPEKK
Subjt:  QEVQQAAKKKEPSKRAPAKKKTTAKSAQISISDD--DEDFEIKEVDPPAAKKGGGR---KAAAANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEKK

Query:  VRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEEV---QPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDEASLDED
        VRKIRASPFNKKSGSLLGR I EEEEED  +DEGK+MGSASSET+EEV   QPA GRSRRANRTQVRYVLSDSD E  SQDSDFDEDEASLDED
Subjt:  VRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEEV---QPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDEASLDED

XP_011651769.2 DNA topoisomerase 2 [Cucumis sativus]

0.0

97.33

Show/hide

Query:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MV+EKKRPLQNSNAANVDSNP GPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEN+KMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFS+EFVIETADGRRLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVV
        PIITKCK GDNWTRVTFKPDL KFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSA SIQAEPPKRYHI+PNERWEIVV
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIAN+VMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYE+WKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQT  LIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
        RFLFP+DDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDD+IVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPK
        TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELC+DRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREK NIDLKPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPK

Query:  ISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDE---VLELKDRLAAYKIESSPEPSDVSAME
        +SRNAPKAPRN KKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDE   VLELKDRLAAYKIESSPEPS+VSAME
Subjt:  ISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDE---VLELKDRLAAYKIESSPEPSDVSAME

Query:  TEVQEVQQ-AAKKKEPSKRAPAKKKTTAKSAQISISDDDED--FEIKEVDPPAAKKGGGR-----KAAAANGKTTKPPAAGAKLGQKLITQMLEPA-ENS
        TEVQEVQQ AAKKKEPSKRAPAKKKTTAKSAQISISDDD D  FEIKEVDPPAAKKGGGR     KAAA N KTTKPPAAGAKLGQKLITQMLEPA ENS
Subjt:  TEVQEVQQ-AAKKKEPSKRAPAKKKTTAKSAQISISDDDED--FEIKEVDPPAAKKGGGR-----KAAAANGKTTKPPAAGAKLGQKLITQMLEPA-ENS

Query:  GISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEEVQPARGRSRRANRT-QVRYVLSDSDGEVASQDSDFDEDEASLDED
        GISPEKKVRKIRASPFNKKSGSLLGRTIGEEEE DENDDEGKLMGSAS ET+EEVQ ARGRSRRANRT QVRYVLSDSDGEVASQDSDFDEDEASLDED
Subjt:  GISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEEVQPARGRSRRANRT-QVRYVLSDSDGEVASQDSDFDEDEASLDED

XP_023527820.1 DNA topoisomerase 2 isoform X1 [Cucurbita pepo subsp. pepo]

0.0

90.89

Show/hide

Query:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M +EKKRPLQNSNAANVDS+P GPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLW+YENDKMVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVF+DNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPV+SFQDYVD YLKSA + Q EPPKRYHI+PNERWEIVV
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVKSYLWVFINALIDNP+FDSQTKETLT R +SFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD++DGEAIELAFSKKKIE+RKNWLRQFE GTHLDQ+E LIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRNVRRML GE MLPMDPWYRGFSGTIEKTATKEGGT+YTVS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRI ELPVRRWT+DYKDFLDSVTRV++K+DKDKEKAAKDPFIEQADHHSDD+ VSIDVHLTEENM+LA+QEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEF+EKRKR LL+NLE ELLKLENKVRFILAVVN EI VSNR++VDLFHELQ KGFTPFPKKTKSVEPE+AGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPK
        TDEAEESPEVVKGER+SDYEYLLAL IGTLTIEKVQELCN+RDK KGEV++LRKATPKSLWL DLDYLEKELDEMDRNDAQ  E+RKQQR K N D+KPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPK

Query:  ISRNAPKAPRNGKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAMETE
        ISRNAPKAPRN KKTSN ET+TESMD TT SSTTTEVANNPVVKPKGKAAPRKAPAKK+GKAAVLDDD+DDEVLELKDRLAAYK+ESSPEPS+VSAMETE
Subjt:  ISRNAPKAPRNGKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAMETE

Query:  VQEVQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDEDFEIKEVDPPAAKKGGGRKAAA--ANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEKKVR
        V +VQ AAKKKEPSKRA AKKKTTAKSAQIS   D+ DFEIKE+ PPAAKKGGGRKAAA     KTTK     A+LGQKLITQMLEP ENSGISPEKKVR
Subjt:  VQEVQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDEDFEIKEVDPPAAKKGGGRKAAA--ANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEKKVR

Query:  KIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEE----VQPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDEASLDED
        KIR SPFNKKSGS+LGR IGEEEEE E  +EGK+MGSASSETT+E    V  ARGRS+R NRTQVRYV+SDSD E   +DSDFDE EA LDED
Subjt:  KIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEE----VQPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDEASLDED

XP_038905935.1 DNA topoisomerase 2 [Benincasa hispida]

0.0

91.78

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Query:  MVIEKKRPLQNSNAANVDSNPE-GPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSM
        M +EKKRPLQNSNAANVDS+P  GPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRS+SYVPGLYKIFDEILVNAADNKQRDPSM
Subjt:  MVIEKKRPLQNSNAANVDSNPE-GPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSM

Query:  DSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKS
        DSVKV+IDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQVFNDNMGKKS
Subjt:  DSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKS

Query:  EPIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIV
        EPIITKCK GDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVP++SFQDYVDLYLKSA + Q EPPKRYHIKPN+RWEIV
Subjt:  EPIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKN
        VTLSEGQFQQVSFVNGI+TIKGGTHV+YITNQI+NYVMTAVNKKNKNANVKAHNVK+YLWVFINALIDNPSFDSQTKETLTKR+NSFGS CELTPEFLKN
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKN

Query:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA+SKQI
Subjt:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESL
        TENKEIQYIKQILGLQQGKEYNNA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESL
Subjt:  TENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESL

Query:  RGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQR
        RGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQT  LIKYSDFVNKELILFSMADLQR
Subjt:  RGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQR

Query:  SIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNV
        SIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRN GGKDHASSRYIYTKLSNV
Subjt:  SIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNV

Query:  TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTV
        TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDII+NVRRML+G TMLPMDPWYRGFSGTIEKTATKEGGT+YTV
Subjt:  TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTV

Query:  SGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMH
        SGIIEEVSDT LRIVELPVRRWT+DYKDFLDSVT+VA+KHDKDKEKAAK+PFIEQADHHSDD+IVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMH
Subjt:  SGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMH

Query:  LFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASN
        LFDANGVIKKYDTPEQILEEFFPLRL+FYEKRKR LL+NLEMELLKLENKVRFIL VVNEEI V NR+KVDLFHELQAKGFTPFPKK KSVEPE+AGAS+
Subjt:  LFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASN

Query:  ETDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKP
        E DEAEESPEVVK  R+SDYEYLL+L IGTLTIEKVQELCN+RDKLKGEVDDLRKATPK+LWLNDLD LEKELDEMD NDAQ ME RK+QR+K N DLKP
Subjt:  ETDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKP

Query:  KISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAMETE
        KISRNAPKAPRNGKKTSN E VTESMDTT+SSTT EVANNPVVKPKGKAAPRKAPAKK GKAAVLDDD DDEVLELKDRLAAYKIESSPEPS+VS METE
Subjt:  KISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAMETE

Query:  VQEVQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDED-----FEIKEVDPPAAKKGGGR----KAAAANGKTTKPPAAGAKLGQKLITQMLEPAENSGI
        V +VQ AAKKKEP+KRA AKKKTTAKSAQ+S+SDDD+D     FE+KEV PPA KKGGGR    KAAA N KTTKPPAA AKLGQKLIT+MLEPAENSGI
Subjt:  VQEVQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDED-----FEIKEVDPPAAKKGGGR----KAAAANGKTTKPPAAGAKLGQKLITQMLEPAENSGI

Query:  SPEKKVRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEG----KLMGSASSETTEE----VQPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDED
        SPEKKVRKIRASPFNKKSGS+LGRTIGEE+EE+E ++E     K+MGSASSETT+E    V PARGRS RANRTQVRYV+SD D E  S+DSD DED
Subjt:  SPEKKVRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEG----KLMGSASSETTEE----VQPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDED

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LEU2 DNA topoisomerase 2

0.0e+00

96.12

Show/hide

Query:  MYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQNCISVFNNGDGVPVEIHQEE
        MYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEN+KMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQNCISVFNNGDGVPVEIHQEE
Subjt:  MYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQNCISVFNNGDGVPVEIHQEE

Query:  KVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPIITKCKEGDNWTRVTFKPDLAKFNMTHLE
        KVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFS+EFVIETADGRRLKKYKQVFNDNMGKKSEPIITKCK GDNWTRVTFKPDL KFNMTHLE
Subjt:  KVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPIITKCKEGDNWTRVTFKPDLAKFNMTHLE

Query:  DDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVEYITN
        DDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSA SIQAEPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVEYITN
Subjt:  DDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVEYITN

Query:  QIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKT
        QIAN+VMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTP+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKT
Subjt:  QIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKT

Query:  EKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNARALRYGH
        EKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNARALRYGH
Subjt:  EKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNARALRYGH

Query:  LMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLT
        LMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYE+WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLT
Subjt:  LMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLT

Query:  KHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKV
        KHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFE               + +  ELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKV
Subjt:  KHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKV

Query:  SQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPI
        SQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFP+DDDKLLNYLNEDGQSIEPTWYMPI
Subjt:  SQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPI

Query:  IPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLD
        IPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLD
Subjt:  IPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLD

Query:  SVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEK
        SVTRVASKHDKDKEKAAKDPFIEQADHHSDD+IVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEK
Subjt:  SVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEK

Query:  RKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETDEAEESPEVVKGERISDYEYLLALPIGTL
        RKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETDEAEESPEVVKGERISDYEYLLALPIGTL
Subjt:  RKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETDEAEESPEVVKGERISDYEYLLALPIGTL

Query:  TIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPKISRNAPKAPRNGKKTSNVETVTESMDTTYS
        TIEKVQELC+DRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREK NIDLKPK+SRNAPKAPRN KKTSNVETVTESMDTTYS
Subjt:  TIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPKISRNAPKAPRNGKKTSNVETVTESMDTTYS

Query:  STTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLD---DDEDDEVLELKDRLAAYKIESSPEPSDVSAMETEVQEV-QQAAKKKEPSKRAPAKKKTTAKS
        STTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLD   DDEDDEVLELKDRLAAYKIESSPEPS+VSAMETEVQEV QQAAKKKEPSKRAPAKKKTTAKS
Subjt:  STTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLD---DDEDDEVLELKDRLAAYKIESSPEPSDVSAMETEVQEV-QQAAKKKEPSKRAPAKKKTTAKS

Query:  AQISISDDDE--DFEIKEVDPPAAKK------GGGRKAAAANGKTTKPPAAGAKLGQKLITQMLEP-AENSGISPEKKVRKIRASPFNKKSGSLLGRTIG
        AQISISDDD   DFEIKEVDPPAAKK      GGGRKAAA N KTTKPPAAGAKLGQKLITQMLEP AENSGISPEKKVRKIRASPFNKKSGSLLGRTIG
Subjt:  AQISISDDDE--DFEIKEVDPPAAKK------GGGRKAAAANGKTTKPPAAGAKLGQKLITQMLEP-AENSGISPEKKVRKIRASPFNKKSGSLLGRTIG

Query:  EEEEEDENDDEGKLMGSASSETTEEVQPARGRSRRANR-TQVRYVLSDSDGEVASQDSDFDEDEASLDED
         EEEEDENDDEGKLMGSAS ET+EEVQ ARGRSRRANR TQVRYVLSDSDGEVASQDSDFDEDEASLDED
Subjt:  EEEEEDENDDEGKLMGSASSETTEEVQPARGRSRRANR-TQVRYVLSDSDGEVASQDSDFDEDEASLDED

A0A1S3CFK5 DNA topoisomerase 2

0.0e+00

96.72

Show/hide

Query:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MV+EKKRPLQNSN ANVDSNP GPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPV+SFQDYVDLYLKSA S QAEPPKRYHIKPNERWEIVV
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVK+YLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQT  LIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRML+GETMLPMDPWYRGFSGTIEKTATKEGGTTYT+S
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKH  DKEKAAKDPFIEQADHHSDD+IVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPK
        TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLD LEKELDE+DRNDAQTMELRKQQR+K N DLKPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPK

Query:  ISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAMETEV
        ISRNAPKAPRN KKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAV D+D+DDEVLELKDRLAAYKIESSPEPS+VSAMETEV
Subjt:  ISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAMETEV

Query:  QEVQQAAKKKEPSKRAPAKKKTTAKSAQISISD--DDEDFEIKEVDPPAAKKG---GGRKAAAANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEKK
        QEV QAAKKKEPSKRAPAKKKTTAKSAQISISD  DD+DFEIKEVDP AAKKG   GGRKAAAANGKTTK PAAG KLGQKLITQMLEPAENSGISPEKK
Subjt:  QEVQQAAKKKEPSKRAPAKKKTTAKSAQISISD--DDEDFEIKEVDPPAAKKG---GGRKAAAANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEKK

Query:  VRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEEV---QPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDEASLDED
        VRKIRASPFNKKSGSLLGR I EEEEED  +DEGK+MGSASSET+EEV   QPA GRSRRANRTQVRYVLSDSD E  SQDSDFDEDEASLDED
Subjt:  VRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEEV---QPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDEASLDED

A0A5A7TZH5 DNA topoisomerase 2

0.0e+00

96.72

Show/hide

Query:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MV+EKKRPLQNSN ANVDSNP GPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPV+SFQDYVDLYLKSA S QAEPPKRYHIKPNERWEIVV
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVK+YLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQT  LIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRML+GETMLPMDPWYRGFSGTIEKTATKEGGTTYT+S
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKH  DKEKAAKDPFIEQADHHSDD+IVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPK
        TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLD LEKELDE+DRNDAQTMELRKQQR+K N DLKPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPK

Query:  ISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAMETEV
        ISRNAPKAPRN KKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAV D+D+DDEVLELKDRLAAYKIESSPEPS+VSAMETEV
Subjt:  ISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAMETEV

Query:  QEVQQAAKKKEPSKRAPAKKKTTAKSAQISISD--DDEDFEIKEVDPPAAKKG---GGRKAAAANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEKK
        QEV QAAKKKEPSKRAPAKKKTTAKSAQISISD  DD+DFEIKEVDP AAKKG   GGRKAAAANGKTTK PAAG KLGQKLITQMLEPAENSGISPEKK
Subjt:  QEVQQAAKKKEPSKRAPAKKKTTAKSAQISISD--DDEDFEIKEVDPPAAKKG---GGRKAAAANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEKK

Query:  VRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEEV---QPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDEASLDED
        VRKIRASPFNKKSGSLLGR I EEEEED  +DEGK+MGSASSET+EEV   QPA GRSRRANRTQVRYVLSDSD E  SQDSDFDEDEASLDED
Subjt:  VRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEEV---QPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDEASLDED

A0A6J1F3D6 DNA topoisomerase 2

0.0e+00

90.9

Show/hide

Query:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M +EKKRPLQNSNAANVDS+P GPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVF+DNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPV+SFQDYVD YLKSA + Q EPPKRYHI+PNERWEIVV
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVKSYLWVFINALIDNP+FDSQTKETLT R +SFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD++DGEAIELAFSKKKIE+RKNWLRQFE GTHLDQ+E LIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRNVRRML GE MLPMDPWYRGFSGTIEKTATKEGGT+YTVS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRI ELPVRRWT+DYKDFLDSVTRV++K+DKDKEKAAKDPFIEQADHHSDD+ VSIDVHLTEENM+LA+QEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEF+EKRKR LL+NLE ELLKLENKVRFILAVVN EI VSNR++VDLFHELQ KGFTPFPKKTKSVEPE+AGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPK
        TDEAEESPEVVKGER+SDYEYLLAL IGTLTIEKVQELCN+RDK KGEV++LRKATPKSLWL DLDYLEKELDEMDRNDAQ  E+RKQQR K N D+KPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPK

Query:  ISRNAPKAPRNGKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAMETE
        ISRNAPKAPRN KKTSN ET+TESMD TT SSTTTEVANNPVVKPKGKAAPRKAPA KKGK AVLDDD+DDEVLELKDRLAAYK+ESSPEPS+VSAMETE
Subjt:  ISRNAPKAPRNGKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAMETE

Query:  VQEVQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDEDFEIKEVDPPAAKKGGGRKAA--AANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEKKVR
        V +VQ AAKKKEPSKRA AKKKTTAKSAQIS   DD DFEIKE+ PPAAKKGGGRKAA  A   KTTK     A+LGQKLITQMLEP ENSGISPEKKVR
Subjt:  VQEVQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDEDFEIKEVDPPAAKKGGGRKAA--AANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEKKVR

Query:  KIRASPFNKKSGSLLGRTIGEEEEE-DENDDEGKLMGSASSETTEE----VQPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDEASLDED
        KIR SPFNKKSGS+LGR IGEEEEE +E  +EGK+MGSASSETT+E    V  ARGRS+R NRTQVRYV+SDSD E   +DSDFDE EA+LDED
Subjt:  KIRASPFNKKSGSLLGRTIGEEEEE-DENDDEGKLMGSASSETTEE----VQPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDEASLDED

A0A6J1F9E0 DNA topoisomerase 2

0.0e+00

90.9

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Query:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M +EKKRPLQNSNAANVDS+P GPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVF+DNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPV+SFQDYVD YLKSA + Q EPPKRYHI+PNERWEIVV
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVKSYLWVFINALIDNP+FDSQTKETLT R +SFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD++DGEAIELAFSKKKIE+RKNWLRQFE GTHLDQ+E LIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRNVRRML GE MLPMDPWYRGFSGTIEKTATKEGGT+YTVS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRI ELPVRRWT+DYKDFLDSVTRV++K+DKDKEKAAKDPFIEQADHHSDD+ VSIDVHLTEENM+LA+QEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEF+EKRKR LL+NLE ELLKLENKVRFILAVVN EI VSNR++VDLFHELQ KGFTPFPKKTKSVEPE+AGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPK
        TDEAEESPEVVKGER+SDYEYLLAL IGTLTIEKVQELCN+RDK KGEV++LRKATPKSLWL DLDYLEKELDEMDRNDAQ  E+RKQQR K N D+KPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPK

Query:  ISRNAPKAPRNGKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAMETE
        ISRNAPKAPRN KKTSN ET+TESMD TT SSTTTEVANNPVVKPKGKAAPRKAPAKK+GK AVLDDD+DDEVLELKDRLAAYK+ESSPEPS+VSAMETE
Subjt:  ISRNAPKAPRNGKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAMETE

Query:  VQEVQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDEDFEIKEVDPPAAKKGGGRKAA--AANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEKKVR
        V +VQ AAKKKEPSKRA AKKKTTAKSAQIS   DD DFEIKE+ PPAAKKGGGRKAA  A   KTTK     A+LGQKLITQMLEP ENSGISPEKKVR
Subjt:  VQEVQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDEDFEIKEVDPPAAKKGGGRKAA--AANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEKKVR

Query:  KIRASPFNKKSGSLLGRTIGEEEEE-DENDDEGKLMGSASSETTEE----VQPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDEASLDED
        KIR SPFNKKSGS+LGR IGEEEEE +E  +EGK+MGSASSETT+E    V  ARGRS+R NRTQVRYV+SDSD E   +DSDFDE EA+LDED
Subjt:  KIRASPFNKKSGSLLGRTIGEEEEE-DENDDEGKLMGSASSETTEE----VQPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDEASLDED

SwissProt top hits

e value

%identity

Alignment

O24308 DNA topoisomerase 2

0.0e+00

62.83

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Query:  KKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKV
        +KRPLQ SNAAN+      P KTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHR++SYVPGLYKIFDEILVNAADNKQRDPSMDS+KV
Subjt:  KKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKV

Query:  NIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPIIT
         ID E N +SV+NNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADGRRLKKYKQVF++NMG K EP+IT
Subjt:  NIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPIIT

Query:  KCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVVTLSE
        KCK  +NWT+VTFKPDL KF M +LE+DVVALMKKRVLD+AGC GKTVKVELNG  +  +SF+DY DL+LK A   +  P  R H K  +RWEI ++LS+
Subjt:  KCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVVTLSE

Query:  GQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNVATKS
        GQFQQVSFVN IATIKGGTHV+YITNQI  Y+M  VNKK K+ANVKAH VK++LWVF+N+LIDNP+FDSQTKETLT R  SFGS C++    LK+V  KS
Subjt:  GQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNVATKS

Query:  GIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKE
        GI+D++LSW +FKQSKDLKKTDG KT+++ G  K EDAN AGG+NSEKCTLILTEGDSAKALAMAGL VVGRD YGVFPLRGKLLNVREASSKQI +N+E
Subjt:  GIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKE

Query:  IQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNAS
        IQ IK+ILGLQQ KEY N ++LRYGHLMIM DQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEF TP+++A+H N T+ SFY+MPEYE+WKE L  +A+
Subjt:  IQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNAS

Query:  GWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRSIPSM
         W IKYYKGLGTST +EGREYF  L +H+KDFIW D+ DG AIELAFSKKK E RK W+R FEPGT  D    LI Y DFVNKELILFS AD        
Subjt:  GWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRSIPSM

Query:  VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLF
                   LF SFK+   KE KV+QF GYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL PNGQFGT N GGKDHAS+RYIYT+LS VTR LF
Subjt:  VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLF

Query:  PKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVSGIIE
         + DDKLL YLNEDG+SIEP WYMPIIP VLVNGSEGIGTGWSSY+PNYNPR+II NVRR+L GE ++PMDPWY+GF GTIEK+A KEGG  Y V+G + 
Subjt:  PKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYTVSGIIE

Query:  EVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDAN
        E+ + T RI ELP+R+WT DYK FL+S+T        D     KDP IE    + DD IV I++ +  E +   +QEGL KKFKLT+T+STSNMHLFDA 
Subjt:  EVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDAN

Query:  GVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETDEA
        G  KK+DTPEQILEEFFPLRL++YEK K  +L NL   LL L+NKVRFIL VVN EI VSNRKK +L  EL+ KGFTP P+K KS +P++AGA+++  E 
Subjt:  GVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETDEA

Query:  EESPE--------VVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNID
        +E  E         V+G    DY+ LL+LPIGTLT+E VQ+L +++ + + E + L      SLWL DLD  EK+LDE+D   A+    R  Q  K    
Subjt:  EESPE--------VVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNID

Query:  LKPKISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAM
           K ++  P+  +N KK  +VE   ++      +         V KPKG+AAP+K           +  + +D++  L++RLAAY IESS E S   AM
Subjt:  LKPKISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAM

Query:  ETEVQEVQQ-AAKKKEPSKRAPAKKKTT-------AKSAQISISDDDEDFEIKEVDPPAAK-KGGGRKAAAANGK------TTKPPAAGAK--------L
        E+E  EVQQ AA KK+ +KR  AKKK++       + +    + DDD+DFE  EV   AA  K GGRK AA N K        K PAA  K         
Subjt:  ETEVQEVQQ-AAKKKEPSKRAPAKKKTT-------AKSAQISISDDDEDFEIKEVDPPAAK-KGGGRKAAAANGK------TTKPPAAGAK--------L

Query:  GQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEE-------VQPARGRSRRANRTQVRYVLSDSD
        GQKL+T ML+PAE +G SPEKKVRK+R SPFNKKSGS+LGR    ++     D      GSAS+    E        QPAR R +RANRTQ++Y LS+S+
Subjt:  GQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEE-------VQPARGRSRRANRTQVRYVLSDSD

Query:  GEVASQDSDFDEDEASLDED
         E   +DSD D + +  +ED
Subjt:  GEVASQDSDFDEDEASLDED

P08096 DNA topoisomerase 2

0.0e+00

45.76

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Query:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVY--ENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPS
        M   ++ PL  +N  N +SN       +   YQ+ +  EH+L RPDTY+GSIE  T  +WV+  E +K+ +++++YVPGLYKIFDEI+VNAADNK RDP+
Subjt:  MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVY--ENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPS

Query:  MDSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKK
        M+++KV +D E N IS++NNG G+P+EIH +EK+Y+PELIFG+LLTSSNYDD +KK TGGRNGYGAKL NIFSTEFV+ETAD  R+KKYKQ + DNM +K
Subjt:  MDSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKK

Query:  SEPIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEI
        SEP+IT  K+ D +T++TFKPDLAKF M  ++DD+V+++K+R+ D+AG + +T KV LN +R+ +  F+ YV++YL S      EPP+  +   N+RW++
Subjt:  SEPIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEI

Query:  VVTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLK
           +S+GQF+QVSFVN I+TI+GGTHV Y+ N+I + +   V K+NK A VKA  +K+Y+ VF+N  I+NPSFDSQTKETLT + ++FGS C L+ +FLK
Subjt:  VVTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLK

Query:  NVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ
         +  KS +++ VL +   K  + L K DG    +I+G+ KLEDAN AG K S KC LILTEGDSAK+LA++GL VVGRD+YGVFPLRGKLLNVREAS  Q
Subjt:  NVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ

Query:  ITENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKES
        I  NKEIQ IK+I+G    K Y + + LRYGHLMIMTDQDHDGSHIKGL+IN++ S +PSLL++P FL++FITPI+K T  N  V +FYT+PEYE WKE+
Subjt:  ITENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKES

Query:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQ
           N  GW IKYYKGLGTS   + + YF  L +H K F    + D E IE+AF+KKK + RK WLR + PG ++D T+  I   DF+N+ELI FSMAD  
Subjt:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQ

Query:  RSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN
        RSIPS+VDGLKPGQRK+++  FKRN + E KVS+ +GYV+  +AYHHGE S+  TI+ +AQ+FVGSNNINLL+PNGQFGTR+ GGK+ ++SRY+ T LS 
Subjt:  RSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN

Query:  VTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYT
        + R LF  +DD+LLNY N++GQ IEP +Y+PI+P VLVNG+EGIGTGWS+++PNYNP+DI  N+R ML GE +  M PWYRGF G+I K A       Y 
Subjt:  VTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTYT

Query:  VSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNM
        +SGII ++ +  + I ELP+R WT D K++L++      K  K         FI   + H  +  V  +V LTE  M  A+ E L+ KFKL+ T +TSNM
Subjt:  VSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNM

Query:  HLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPF--PKKTKSVEPEIAG
          FDA+G IKKYD+ E IL EF+ +RL  Y++RK  +++ LE    +  N+ RFI  ++  E+ VS +KK DL  EL+ K F P   PKK   V+ E+  
Subjt:  HLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPF--PKKTKSVEPEIAG

Query:  ASNETDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNID
          N   E E+S +V + E    Y YLL++P+ +LT E+  EL   +D++  E+D L K TPK LWL+DLD  E   +++  +D Q   L ++Q  +  + 
Subjt:  ASNETDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNID

Query:  LKPKISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPE-PSDVSA
               N  K    GK T                           KP+  A    + A KK  ++   + +       +  L  +     PE  SD++ 
Subjt:  LKPKISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPE-PSDVSA

Query:  METEVQEVQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDEDFEIKEVDPPAAKKGGGRKAAAANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEK-
        ++TE      + ++   SK        + KS + S S D ED          +KK   + AA+A+G+       G K  + + T +    +   + P   
Subjt:  METEVQEVQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDEDFEIKEVDPPAAKKGGGRKAAAANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEK-

Query:  KVRKIRASPFNKKSGSLLGRTIGEEEEEDENDD---EGKLMGSASSETTEEV-----QPARGRSRRANRTQVR---YV--LSDSDGEVASQDSDF----D
        K   I ++  + K+      ++ ++  ED++DD    G      +S T  E       P R R  R     V+   YV    DS  E + QD  F    D
Subjt:  KVRKIRASPFNKKSGSLLGRTIGEEEEEDENDD---EGKLMGSASSETTEEV-----QPARGRSRRANRTQVR---YV--LSDSDGEVASQDSDF----D

Query:  EDEASLDE
        ED    DE
Subjt:  EDEASLDE

P11388 DNA topoisomerase 2-alpha

0.0e+00

44.5

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Query:  MVIEKKRPLQNSNAANVDSNPEGPKK--TIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMV-HRSISYVPGLYKIFDEILVNAADNKQRDP
        M +   +P+  +   N     E  KK  ++E +YQKK+QLEHILLRPDTY+GS+E  TQ +WVY+ D  + +R +++VPGLYKIFDEILVNAADNKQRDP
Subjt:  MVIEKKRPLQNSNAANVDSNPEGPKK--TIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMV-HRSISYVPGLYKIFDEILVNAADNKQRDP

Query:  SMDSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGK
         M  ++V ID E N IS++NNG G+PV  H+ EK+YVP LIFG LLTSSNYDD EKK TGGRNGYGAKL NIFST+F +ETA     K +KQ + DNMG+
Subjt:  SMDSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGK

Query:  KSEPIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWE
          E +  K   G+++T +TF+PDL+KF M  L+ D+VALM +R  D+AG   K VKV LNG ++PV+ F+ YVD+YLK          K  H + N RWE
Subjt:  KSEPIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWE

Query:  IVVTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNK-NANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEF
        + +T+SE  FQQ+SFVN IAT KGG HV+Y+ +QI   ++  V KKNK    VKAH VK+++W+F+NALI+NP+FDSQTKE +T +  SFGS C+L+ +F
Subjt:  IVVTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNK-NANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEF

Query:  LKNVATKSGIMDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREAS
        +K  A   GI++S+L+WV FK    L KK    K  +I GI KL+DAN AGG+NS +CTLILTEGDSAK LA++GLGVVGRD YGVFPLRGK+LNVREAS
Subjt:  LKNVATKSGIMDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREAS

Query:  SKQITENKEIQYIKQILGLQQGKEY---NNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEY
         KQI EN EI  I +I+GLQ  K Y   ++ + LRYG +MIMTDQD DGSHIKGLLINFIH  WPSLLR   FL EFITPIVK + KN   ++FY++PE+
Subjt:  SKQITENKEIQYIKQILGLQQGKEY---NNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEY

Query:  ESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFE-----------PGTHL-DQTENLIK
        E WK S   N   W +KYYKGLGTSTSKE +EYF  + +H+  F +    D  AI LAFSKK+I+DRK WL  F            P  +L  QT   + 
Subjt:  ESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFE-----------PGTHL-DQTENLIK

Query:  YSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRN
        Y+DF+NKELILFS +D +RSIPSMVDGLKPGQRK+LF  FKRN  +E KV+Q +G V+E S+YHHGE SL  TII +AQ+FVGSNN+NLL P GQFGTR 
Subjt:  YSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRN

Query:  HGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRG
        HGGKD AS RYI+T LS++ R LFP  DD  L +L +D Q +EP WY+PIIP VL+NG+EGIGTGWS  +PN++ R+I+ N+RR+++GE  LPM P Y+ 
Subjt:  HGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRG

Query:  FSGTIEKTATKEGGTTYTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQ
        F GTIE+ A  +    Y +SG +  ++ TT+ I ELPVR WT  YK+      +V        EK    P I     +  D  V   V +TEE +  A +
Subjt:  FSGTIEKTATKEGGTTYTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQ

Query:  EGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGF
         GL K FKL T+++ ++M LFD  G +KKYDT   IL +FF LRL++Y  RK  LL  L  E  KL N+ RFIL  ++ +I + N+ K +L   L  +G+
Subjt:  EGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGF

Query:  TPFPKKTKSVEPEIAGASNETDEAEESPEVVKGERISD----YEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMD
           P K      +      E +E++   E  K + ++D    + YLL +P+  LT EK  ELC  R++ + E+D L++ +P  LW  DL    +EL+ ++
Subjt:  TPFPKKTKSVEPEIAGASNETDEAEESPEVVKGERISD----YEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMD

Query:  RNDAQ------------------------------------TMELRKQQREKGNIDLKPKISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNP
          + Q                                    T+E++ +  +K    +K + +  +P+   +G +   ++   E        T T+     
Subjt:  RNDAQ------------------------------------TMELRKQQREKGNIDLKPKISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNP

Query:  VVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYK------IESSPEPSDVSAMETEVQEVQQAAKKKEPSKRAPAKKKTTAK------SAQ
          KP  K   R   +  +   +  + + D    E + R AA K      ++S  + SD      +   V        PS  +P K KT+ K        Q
Subjt:  VVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYK------IESSPEPSDVSAMETEVQEVQQAAKKKEPSKRAPAKKKTTAK------SAQ

Query:  ISISDDDEDFEIK------------------EVDPPAAKKGGGRKAAAANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGS
         S+  D E  ++K                  E+  P  KK    K  AA  +++       K      T+  +PA NSG+S +    K +     K S S
Subjt:  ISISDDDEDFEIK------------------EVDPPAAKKGGGRKAAAANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGS

Query:  ---------LLGRTIGEEEEEDENDD
                 ++ + +  ++ + E+DD
Subjt:  ---------LLGRTIGEEEEEDENDD

P30182 DNA topoisomerase 2

0.0e+00

63.48

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Query:  KRPLQNSNAANVDSNPEGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNAANV   P   +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNAANVDSNPEGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADG+RLKKYKQVF +NMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPP-KRYHIKPNERWEIV
        P+ITKC + +NWT+VTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PV+SF DYVDLYL +A   + E P  R   K N+RWE+ 
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPP-KRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKN
        V+LSEGQFQQVSFVN IATIKGGTHV+Y+T+QI N+++ AVNKKNKNANVKAHNVK++LWVF+NALIDNP+FDSQTKETLT R +SFGS CEL+ +FLK 
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKN

Query:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE
        T NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT K GT  VLSFY+MPEYE WKE
Subjt:  TENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADL
        SL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ +  + YSDFVNKELILFSMADL
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADL

Query:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTY
         VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I+ NVRR+L GE+M+PMDPWYRGF GTIEKTA+KEGG TY
Subjt:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTY

Query:  TVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSN
        T++G+ EEV +TT+RI ELP+RRW  DYK+FL S+     K D         PF +    ++D++ V  D+ L+EENML A QEG  KKFKLTTT++TSN
Subjt:  TVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSN

Query:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGA
        MHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  ++ N+E+ELLKLENK RFILAV++ EI V+ RKK D+  +L+ KGFTPFP+K +SVE  IAGA
Subjt:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGA

Query:  SNETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMEL--RKQ
         ++ D AEE  E++            S+Y+YLLA+ I +LTIEKV+EL  DRDK+   V D++K TPKSLWL+DL+ L+KEL+++D  DAQ  +     Q
Subjt:  SNETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMEL--RKQ

Query:  QREKGNIDLKPKISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKK----GKAAVLDDDEDDEVLELKDRLAAYKI
        ++ +       K+ R APK P   KKT+   + +E+ + +YS+  T+     VVKPK +   +K  ++ +      +A+  D+   EV++ K R  A K 
Subjt:  QREKGNIDLKPKISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKK----GKAAVLDDDEDDEVLELKDRLAAYKI

Query:  ESSPEPSDVSAMETEVQEVQQAAKKKEPSK--RAPAKKKTTAKSAQISISDDDEDFEIKEVDPPAAKKGGGRKAAAANGKTTKPPAAGAKLGQKLI--TQ
              +  +A E E  E+   A++        APA    TA++++    DDD+D  + EV P    K GGRK AA   K  KPPAA  K G++ +  T+
Subjt:  ESSPEPSDVSAMETEVQEVQQAAKKKEPSK--RAPAKKKTTAKSAQISISDDDEDFEIKEVDPPAAKKGGGRKAAAANGKTTKPPAAGAKLGQKLI--TQ

Query:  MLEPAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEEVQPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDE
        +L      G+SPEKKVRK+R+SPFNKKS S++ R    +EEE   +    + G++SSE +     A  R +RANR ++ YVLSDS+ E A+ DS+FD+ E
Subjt:  MLEPAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEEVQPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDE

Query:  ASLDED
           D++
Subjt:  ASLDED

Q55BP5 Probable DNA topoisomerase 2

0.0e+00

46.88

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Query:  EKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVK
        +K     N N     ++     K+IEE+YQKK  L+ ILLRPDTY+GS E+  + LWV+E+ +MVHR +S+VPG+YKIFDEILVNAADNKQR+ +M  +K
Subjt:  EKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVK

Query:  VNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPII
        V ID E+  ISV N+G G+P+++H E K+Y+PELIFG+LLTSS+YDD+EK+ TGGRNG+GAKL NIFST+F++E AD +  K YKQ F +NM  K +P I
Subjt:  VNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPII

Query:  TKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVVTLS
        T  +   ++T++TF P+L +F M   +DD+VAL+ KRV D+AGC   T+KV LN + + +RSF+ Y++LY       +   PK Y+ K ++RWE+ VTLS
Subjt:  TKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVVTLS

Query:  -EGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNK-NANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNVA
         E QF QVSFVN I T+KGGTHV +  + I   +   VNKKNK +A++K   +K++L VF+N LI+NP FDSQTKETLT + +SFGS CE + +F+K V 
Subjt:  -EGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNK-NANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNVA

Query:  -TKSGIMDSVLSWVNFKQSKDLKK--TDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ
         +KSGI+ S+L +  FK    LK+  + G K  K+S I KL+DAN AGG  SE CTLILTEGDSAK+LA AG+ VVG+D YG FPL+GKLLNVR+ S+K 
Subjt:  -TKSGIMDSVLSWVNFKQSKDLKK--TDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ

Query:  ITENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKES
        +  N EI  I  ILGL+ GK Y     LRYGHLMIMTDQDHDGSHIKGL+IN +H FWP+LLR+P FLVEFITPIVK    N   +SFYTMPE+  W+E+
Subjt:  ITENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKES

Query:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQ-TENLIKYSDFVNKELILFSMADL
           N  GW +KYYKGLGTST  EG+EYF  L +HK DF W D+   + IELAFSK + +DRK W+ +   GT L+Q     + YSDF+NKEL+LFS+AD 
Subjt:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQ-TENLIKYSDFVNKELILFSMADL

Query:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        +RSIP++VDGLK   RK L+  FKRN  KE KV+Q  GYVSEHSAYHHGE SL STI+GMAQ+FVGSNNINLL P G +GTR  GGKD +S+RYI+T+L+
Subjt:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIE-KTATKEGGTT
        ++ R ++  DDD +L+ + +DG+ ++P +Y+P+IP +LVNG  GIGTGWSS +PNYNPRD+I+N+R  ++G+ + P+ PWYRGF G+IE    +K  G  
Subjt:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIE-KTATKEGGTT

Query:  YTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSV----TRVASKHDKDKEKAAK---------DPFIEQADHHSDDRIVS-------------IDVHL
        Y   GI +++SD    I ELP+  WT DY++ LD +    TR   K +K+K+ A++             ++ D   D+  V+               +H 
Subjt:  YTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSV----TRVASKHDKDKEKAAK---------DPFIEQADHHSDDRIVS-------------IDVHL

Query:  TEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVD
          + +    +  ++K FKL +T++ +NM +FD  G I+++ T   + E FFPLR++ Y+ RK  L + L  E  +L NK RFILAVVN+E+ +SN KKVD
Subjt:  TEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVD

Query:  LFHELQAKGFTPFPKK--TKSVEPEIAGASNETDE------AEESPEVVKGERISD---YEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKS
        L ++L+   F     K   KS   +I    N  DE      ++E  +  + E+  D   Y+YLL+LP+ +LT+E+V++L  +RD  K E D L     + 
Subjt:  LFHELQAKGFTPFPKK--TKSVEPEIAGASNETDE------AEESPEVVKGERISD---YEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKS

Query:  LWLNDLDYLEKELDEMDRNDA----QTMELRKQQREKG---NIDLKPKISRNAPKAP--RNGKKTSNVETVTESM----------DTTYSSTTTEVANN-
        ++  DLD LEK LD+ D  D     QT  L+K+ + K       +  K+ ++  +AP  +  K T  + T T+S           DTT +ST+T  ++N 
Subjt:  LWLNDLDYLEKELDEMDRNDA----QTMELRKQQREKG---NIDLKPKISRNAPKAP--RNGKKTSNVETVTESM----------DTTYSSTTTEVANN-

Query:  -PVVKPKGKAAPRKAPAKKKGKAAVLDDD---EDDEVLELKDRLAAYKIESSPEPSDVSAMETEVQEVQQAAKKKEPSKRAPA----------KKKTTAK
         P+     K   +  PA KK     LD D   +DD V+  K +    K     E SD S  E++ QE  Q +  + P KR+ A          KK TT+K
Subjt:  -PVVKPKGKAAPRKAPAKKKGKAAVLDDD---EDDEVLELKDRLAAYKIESSPEPSDVSAMETEVQEVQQAAKKKEPSKRAPA----------KKKTTAK

Query:  SAQISISDDDED
        S  I     D++
Subjt:  SAQISISDDDED

Arabidopsis top hits

e value

%identity

Alignment

AT3G10270.1 DNA GYRASE B1

2.2e-22

23.77

Show/hide

Query:  GLYKIFDEILVNAADNKQRDPSMDSVKVNIDV---EQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFS
        GL+ +  EIL NA D  Q           IDV     + +S+ +NG G+P ++H        E +   L     +         +GG +G G  + N  S
Subjt:  GLYKIFDEILVNAADNKQRDPSMDSVKVNIDV---EQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFS

Query:  TEF-VIETADGRRLKKYKQVFNDNMGKKSEPIIT-KC------KEGDNWTRVTFKPDLAKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVP
            VI   DG    +++Q ++     + +P+ T  C        G   T + F PD   F      + + +A   + +  L   +  ++K E +     
Subjt:  TEF-VIETADGRRLKKYKQVFNDNMGKKSEPIIT-KC------KEGDNWTRVTFKPDLAKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVP

Query:  VRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVVTLSEGQFQ---------QVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHN
        V S   Y     +    +  +  K  H     R EI  +  +   Q          + + N I TI GGTH+E +   +    + ++ KK K   VK + 
Subjt:  VRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVVTLSEGQFQ---------QVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHN

Query:  VKSYLWV-------------------------------------FINALIDNPSFDSQTKETL----------TKRANSFGSACELTPEFLKNVATKSGI
        + S  W+                                      ++  + NP F+ QTK  L                     EL P+ L+++ +KS  
Subjt:  VKSYLWV-------------------------------------FINALIDNPSFDSQTKETL----------TKRANSFGSACELTPEFLKNVATKSGI

Query:  MDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEI
        +++  + +  K++++L ++    K+  + G  KL D +      SE   + + EGDSA   A  G     R F  + PLRGK+LN+       + +N+EI
Subjt:  MDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEI

Query:  QYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNASG
        Q +   LGL    E  N   LRY  ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K   +       Y     +    S  GNAS 
Subjt:  QYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNASG

Query:  WSIKYYKGLG
        ++I+ +KGLG
Subjt:  WSIKYYKGLG

AT3G23890.1 topoisomerase II

0.0e+00

63.48

Show/hide

Query:  KRPLQNSNAANVDSNPEGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNAANV   P   +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNAANVDSNPEGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADG+RLKKYKQVF +NMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPP-KRYHIKPNERWEIV
        P+ITKC + +NWT+VTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PV+SF DYVDLYL +A   + E P  R   K N+RWE+ 
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPP-KRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKN
        V+LSEGQFQQVSFVN IATIKGGTHV+Y+T+QI N+++ AVNKKNKNANVKAHNVK++LWVF+NALIDNP+FDSQTKETLT R +SFGS CEL+ +FLK 
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKN

Query:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE
        T NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT K GT  VLSFY+MPEYE WKE
Subjt:  TENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADL
        SL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ +  + YSDFVNKELILFSMADL
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADL

Query:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTY
         VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I+ NVRR+L GE+M+PMDPWYRGF GTIEKTA+KEGG TY
Subjt:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTY

Query:  TVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSN
        T++G+ EEV +TT+RI ELP+RRW  DYK+FL S+     K D         PF +    ++D++ V  D+ L+EENML A QEG  KKFKLTTT++TSN
Subjt:  TVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSN

Query:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGA
        MHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  ++ N+E+ELLKLENK RFILAV++ EI V+ RKK D+  +L+ KGFTPFP+K +SVE  IAGA
Subjt:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGA

Query:  SNETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMEL--RKQ
         ++ D AEE  E++            S+Y+YLLA+ I +LTIEKV+EL  DRDK+   V D++K TPKSLWL+DL+ L+KEL+++D  DAQ  +     Q
Subjt:  SNETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMEL--RKQ

Query:  QREKGNIDLKPKISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKK----GKAAVLDDDEDDEVLELKDRLAAYKI
        ++ +       K+ R APK P   KKT+   + +E+ + +YS+  T+     VVKPK +   +K  ++ +      +A+  D+   EV++ K R  A K 
Subjt:  QREKGNIDLKPKISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKK----GKAAVLDDDEDDEVLELKDRLAAYKI

Query:  ESSPEPSDVSAMETEVQEVQQAAKKKEPSK--RAPAKKKTTAKSAQISISDDDEDFEIKEVDPPAAKKGGGRKAAAANGKTTKPPAAGAKLGQKLI--TQ
              +  +A E E  E+   A++        APA    TA++++    DDD+D  + EV P    K GGRK AA   K  KPPAA  K G++ +  T+
Subjt:  ESSPEPSDVSAMETEVQEVQQAAKKKEPSK--RAPAKKKTTAKSAQISISDDDEDFEIKEVDPPAAKKGGGRKAAAANGKTTKPPAAGAKLGQKLI--TQ

Query:  MLEPAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEEVQPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDE
        +L      G+SPEKKVRK+R+SPFNKKS S++ R    +EEE   +    + G++SSE +     A  R +RANR ++ YVLSDS+ E A+ DS+FD+ E
Subjt:  MLEPAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEEVQPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDE

Query:  ASLDED
           D++
Subjt:  ASLDED

AT3G23890.2 topoisomerase II

0.0e+00

63.96

Show/hide

Query:  KRPLQNSNAANVDSNPEGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSNAANV   P   +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNAANVDSNPEGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADG+RLKKYKQVF +NMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPP-KRYHIKPNERWEIV
        P+ITKC + +NWT+VTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PV+SF DYVDLYL +A   + E P  R   K N+RWE+ 
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPP-KRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKN
        V+LSEGQFQQVSFVN IATIKGGTHV+Y+T+QI N+++ AVNKKNKNANVKAHNVK++LWVF+NALIDNP+FDSQTKETLT R +SFGS CEL+ +FLK 
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKN

Query:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE
        T NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT K GT  VLSFY+MPEYE WKE
Subjt:  TENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADL
        SL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ +  + YSDFVNKELILFSMADL
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADL

Query:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTY
         VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I+ NVRR+L GE+M+PMDPWYRGF GTIEKTA+KEGG TY
Subjt:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRGFSGTIEKTATKEGGTTY

Query:  TVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSN
        T++G+ EEV +TT+RI ELP+RRW  DYK+FL S+     K D         PF +    ++D++ V  D+ L+EENML A QEG  KKFKLTTT++TSN
Subjt:  TVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSN

Query:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGA
        MHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  ++ N+E+ELLKLENK RFILAV++ EI V+ RKK D+  +L+ KGFTPFP+K +SVE  IAGA
Subjt:  MHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGA

Query:  SNETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMEL--RKQ
         ++ D AEE  E++            S+Y+YLLA+ I +LTIEKV+EL  DRDK+   V D++K TPKSLWL+DL+ L+KEL+++D  DAQ  +     Q
Subjt:  SNETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMEL--RKQ

Query:  QREKGNIDLKPKISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGK-AAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESS
        ++ +       K+ R APK P   KKT+   + +E+ + +YS+  T+     VVKPKG+  A +KAPA  K       + E+DE+L+L  RLA Y   S+
Subjt:  QREKGNIDLKPKISRNAPKAPRNGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGK-AAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESS

Query:  PEPSDVSAMETEVQEVQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDEDFEIKEVDPPAAKKGGGRKAAAANGKTTKPPAAGAKLGQKLI--TQMLEPA
        P  S                             KT   S  I++ DDD+D  + EV P    K GGRK AA   K  KPPAA  K G++ +  T++L   
Subjt:  PEPSDVSAMETEVQEVQQAAKKKEPSKRAPAKKKTTAKSAQISISDDDEDFEIKEVDPPAAKKGGGRKAAAANGKTTKPPAAGAKLGQKLI--TQMLEPA

Query:  ENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEEVQPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDEASLDE
           G+SPEKKVRK+R+SPFNKKS S++ R    +EEE   +    + G++SSE +     A  R +RANR ++ YVLSDS+ E A+ DS+FD+ E   D+
Subjt:  ENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGKLMGSASSETTEEVQPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDEASLDE

Query:  D
        +
Subjt:  D

AT5G04130.1 DNA GYRASE B2

2.9e-27

24.76

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Query:  EMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVE-QNCISVFNNGDGVPVEIHQ
        E  Q    L+ +  RP  Y+GS                         GL+ +  EIL NA D  Q   +    KV++ +     +SV +NG G+P ++H 
Subjt:  EMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVE-QNCISVFNNGDGVPVEIHQ

Query:  EEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPIIT-KCK------EGDNWTRVTFKP
          K    E +   L     +  T      +GG +G G  + N  S    +E +  R   ++KQ ++     + +PI T  C+      +G   T + F P
Subjt:  EEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPIIT-KCK------EGDNWTRVTFKP

Query:  DLAKFNMTHLEDDVVALMKKRVLDLAGCLGK-TVKVELNGQRVPVRSFQDYVDL-YLKSAPSIQAEPPKRYHIKPNERWEIVVTLSEGQFQ---------
        D   F  T +E D   +   R+ +LA    K T+ ++          + +Y     L    S         H     R EI     +   Q         
Subjt:  DLAKFNMTHLEDDVVALMKKRVLDLAGCLGK-TVKVELNGQRVPVRSFQDYVDL-YLKSAPSIQAEPPKRYHIKPNERWEIVVTLSEGQFQ---------

Query:  QVSFVNGIATIKGGTHVEYITNQIANYVMTAVNK----KNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETL----------TKRANSFGSACELTP
         + + N I TI GGTH+E +   +   + T   K    K K+ ++   +V+  L   ++  + NP F+ QTK  L                     EL P
Subjt:  QVSFVNGIATIKGGTHVEYITNQIANYVMTAVNK----KNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETL----------TKRANSFGSACELTP

Query:  EFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVRE
        + L+++ +KS  +++  + +  K++++L ++    K+  + G  KL D +    + SE   + + EGDSA   A  G     R F  + PLRGK+LN+  
Subjt:  EFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVRE

Query:  ASSKQITENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYE
             + +N+EIQ +   LGL    E      LRY  ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K   +       Y   + +
Subjt:  ASSKQITENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYE

Query:  SWKESLRGNASGWSIKYYKGLG
            +   NAS ++I+ +KGLG
Subjt:  SWKESLRGNASGWSIKYYKGLG

Sequences

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CDS sequence

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ATGGTTATCGAAAAGAAACGGCCACTTCAGAACAGCAACGCCGCCAATGTCGACTCCAATCCGGAAGGTCCAAAGAAAACAATCGAAGAAATGTACCAAAAGAAGTCTCA
GCTCGAGCACATTCTTCTCAGGCCCGATACCTATGTCGGATCTATTGAAAAGCATACCCAAAACCTCTGGGTTTACGAGAATGACAAAATGGTCCACCGATCAATCTCTT
ACGTGCCTGGTCTTTACAAGATCTTTGATGAAATCTTGGTCAATGCTGCAGATAATAAGCAGAGAGACCCTTCCATGGATTCTGTCAAGGTCAATATTGATGTCGAACAG
AACTGTATCAGTGTTTTCAACAATGGAGATGGAGTTCCGGTTGAAATTCATCAGGAAGAGAAGGTTTATGTGCCTGAGTTGATCTTTGGACATTTGTTGACTAGTAGTAA
CTACGATGATACCGAAAAGAAAACCACTGGTGGACGGAATGGGTATGGTGCGAAACTTACCAATATTTTTTCTACTGAATTTGTGATCGAAACGGCTGATGGAAGGCGCC
TGAAGAAGTATAAGCAGGTATTCAATGATAACATGGGTAAAAAATCAGAGCCGATTATAACGAAGTGCAAGGAGGGTGATAATTGGACCAGAGTAACTTTTAAGCCAGAC
CTGGCAAAATTTAACATGACCCATCTTGAAGATGATGTTGTTGCACTGATGAAAAAGAGAGTCTTAGATTTGGCTGGATGCCTTGGTAAAACCGTGAAGGTTGAGCTGAA
TGGACAAAGGGTCCCTGTAAGATCATTTCAAGATTATGTAGATCTCTACCTCAAATCAGCACCCTCAATCCAGGCGGAACCTCCCAAAAGGTATCACATTAAGCCTAATG
AGAGATGGGAAATTGTGGTGACCTTAAGTGAGGGCCAGTTCCAACAGGTCAGCTTTGTGAACGGGATTGCAACAATCAAGGGTGGGACTCATGTTGAATACATCACTAAT
CAAATAGCAAATTATGTGATGACTGCTGTAAATAAGAAGAACAAAAATGCTAACGTGAAGGCTCATAATGTGAAGAGCTATTTGTGGGTTTTTATCAATGCTCTCATTGA
TAATCCATCCTTCGACTCCCAAACCAAGGAAACTTTGACAAAACGTGCAAACAGTTTCGGTTCTGCATGTGAACTTACGCCAGAATTTTTGAAGAATGTGGCCACAAAAT
CTGGAATTATGGACAGCGTTCTCTCATGGGTTAATTTCAAGCAAAGCAAAGATTTGAAGAAAACGGATGGAGCAAAAACAGAAAAGATTAGTGGCATCGAAAAGTTGGAG
GACGCCAATTGTGCTGGAGGGAAGAACTCAGAAAAATGTACCTTAATTTTGACGGAAGGAGATTCAGCTAAGGCCCTTGCAATGGCTGGGCTCGGTGTAGTAGGACGAGA
CTTTTATGGTGTATTCCCACTCAGAGGTAAATTGCTCAATGTGAGGGAAGCAAGTAGTAAACAAATAACAGAGAATAAAGAAATTCAGTACATCAAGCAAATTCTTGGAC
TTCAGCAAGGGAAGGAATACAACAATGCAAGGGCTTTGAGATACGGTCATTTGATGATTATGACCGATCAGGACCACGATGGCTCACACATTAAAGGACTCTTGATCAAC
TTTATTCATTCTTTTTGGCCTTCTCTCCTTAGAGTGCCATCGTTCTTGGTTGAATTCATAACGCCAATTGTCAAGGCTACTCATAAGAATGGAACTGTTTTATCTTTCTA
TACCATGCCCGAGTATGAATCCTGGAAAGAGAGCTTGAGGGGCAATGCAAGTGGCTGGTCAATCAAGTACTATAAGGGGTTGGGCACAAGCACATCAAAAGAAGGAAGAG
AGTACTTTGAACAGCTGACAAAGCACAAGAAAGATTTTATTTGGCAAGATGATAATGACGGGGAGGCAATTGAGCTTGCTTTCAGTAAGAAGAAGATTGAAGATAGAAAG
AATTGGCTCCGTCAATTTGAGCCTGGTACCCATCTAGATCAGACAGAAAACTTGATAAAATACAGTGACTTTGTTAACAAGGAGCTTATATTATTTTCAATGGCTGATTT
ACAAAGGTCTATTCCGTCAATGGTTGATGGCCTTAAGCCTGGCCAAAGGAAGATCCTTTTCTGTTCTTTCAAGAGGAACTTTATCAAAGAAGCAAAGGTTTCACAATTTT
CCGGTTACGTATCTGAGCACTCTGCTTATCATCATGGTGAGCAGAGTCTTGCTAGTACCATCATTGGAATGGCACAGGACTTTGTTGGCAGTAACAACATTAATCTTCTT
CTACCAAATGGACAGTTTGGCACACGGAACCATGGAGGCAAAGATCATGCAAGTTCTAGGTACATTTACACTAAACTTTCAAATGTCACACGGTTCCTTTTCCCGAAAGA
TGATGACAAGCTTCTTAACTACTTAAATGAAGATGGCCAGTCGATTGAACCAACCTGGTATATGCCTATCATCCCAACCGTTCTTGTCAATGGAAGTGAAGGAATTGGAA
CTGGTTGGAGTTCATACGTTCCAAACTATAATCCTAGAGACATCATTAGAAATGTCAGACGCATGTTGGAGGGTGAAACGATGTTGCCAATGGATCCGTGGTATAGAGGT
TTTTCAGGAACTATAGAGAAAACTGCCACTAAAGAAGGAGGTACTACTTACACTGTTAGTGGAATTATAGAGGAGGTCAGCGATACGACGTTGAGAATAGTTGAATTGCC
AGTCCGCCGATGGACTAGTGACTACAAGGACTTTCTTGACTCTGTCACAAGAGTTGCATCAAAGCATGACAAAGATAAAGAAAAAGCAGCAAAGGATCCTTTTATTGAGC
AAGCTGATCACCACAGCGATGACAGAATTGTTTCCATTGATGTTCACTTAACAGAGGAAAACATGTTATTGGCCATCCAGGAAGGTTTGAAGAAGAAATTCAAACTAACT
ACAACTGTCAGCACCAGCAACATGCACCTGTTTGATGCAAATGGCGTCATTAAGAAATATGACACCCCAGAACAAATTCTTGAGGAATTTTTCCCCCTTAGACTTGAATT
CTACGAGAAAAGAAAGAGAATTCTTTTGGATAACCTTGAAATGGAGTTGCTTAAACTGGAAAACAAGGTGAGGTTCATTCTTGCTGTTGTGAATGAAGAGATAAAAGTAA
GCAATAGAAAAAAGGTTGATTTGTTCCACGAGCTTCAAGCGAAAGGCTTTACACCCTTTCCAAAGAAGACTAAATCTGTTGAGCCGGAGATTGCTGGGGCATCTAATGAA
ACTGATGAAGCAGAGGAGAGCCCGGAAGTGGTAAAAGGGGAACGAATTAGTGATTATGAGTATCTACTAGCTCTGCCAATTGGAACCTTGACCATCGAGAAGGTTCAGGA
GCTATGTAATGATAGAGACAAGCTGAAAGGAGAAGTGGATGATTTGAGGAAGGCAACCCCCAAGTCTTTGTGGCTGAATGACCTTGATTATCTTGAGAAAGAGCTTGATG
AGATGGATAGAAATGATGCTCAGACAATGGAGTTAAGAAAACAACAGCGAGAGAAAGGAAATATCGATTTAAAGCCAAAAATCTCAAGAAATGCACCAAAAGCTCCACGT
AACGGTAAGAAAACCAGCAATGTGGAAACTGTCACCGAAAGTATGGACACAACATATAGTTCTACAACAACGGAAGTTGCAAATAACCCGGTGGTGAAGCCAAAAGGCAA
AGCAGCTCCAAGAAAAGCTCCTGCTAAAAAGAAGGGTAAAGCAGCAGTTCTTGACGATGACGAAGATGACGAAGTCCTCGAGCTTAAAGATCGTCTTGCTGCCTACAAAA
TTGAGTCATCTCCTGAACCATCAGACGTTTCAGCCATGGAAACTGAAGTGCAGGAAGTACAACAAGCGGCCAAGAAGAAAGAACCTAGCAAGAGAGCACCTGCCAAGAAG
AAAACTACTGCAAAGTCAGCTCAGATCTCCATTAGCGACGATGACGAAGATTTCGAAATAAAGGAAGTAGACCCTCCGGCAGCCAAGAAGGGAGGAGGAAGAAAGGCAGC
TGCAGCGAATGGCAAAACAACCAAGCCCCCTGCTGCAGGAGCGAAGTTGGGGCAGAAACTGATAACTCAAATGCTAGAACCAGCAGAGAACTCCGGCATCTCACCAGAGA
AGAAAGTGAGGAAGATAAGAGCATCACCTTTCAACAAGAAAAGTGGCTCTTTATTGGGAAGAACAATAGGGGAAGAAGAAGAAGAGGATGAAAATGACGATGAAGGGAAG
TTGATGGGTTCTGCTTCTTCCGAGACTACTGAAGAAGTTCAGCCGGCGAGAGGGAGATCTCGGAGAGCAAACAGAACACAGGTCAGGTATGTGCTTAGTGATTCAGATGG
TGAGGTAGCTTCTCAGGATTCAGACTTCGATGAAGACGAAGCCAGCCTTGATGAAGATTGA

mRNA sequence

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Protein sequence

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MVIEKKRPLQNSNAANVDSNPEGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQ
NCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPIITKCKEGDNWTRVTFKPD
LAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVRSFQDYVDLYLKSAPSIQAEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVEYITN
QIANYVMTAVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLE
DANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNARALRYGHLMIMTDQDHDGSHIKGLLIN
FIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRK
NWLRQFEPGTHLDQTENLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL
LPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLEGETMLPMDPWYRG
FSGTIEKTATKEGGTTYTVSGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKDKEKAAKDPFIEQADHHSDDRIVSIDVHLTEENMLLAIQEGLKKKFKLT
TTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDYLEKELDEMDRNDAQTMELRKQQREKGNIDLKPKISRNAPKAPR
NGKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVLDDDEDDEVLELKDRLAAYKIESSPEPSDVSAMETEVQEVQQAAKKKEPSKRAPAKK
KTTAKSAQISISDDDEDFEIKEVDPPAAKKGGGRKAAAANGKTTKPPAAGAKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSLLGRTIGEEEEEDENDDEGK
LMGSASSETTEEVQPARGRSRRANRTQVRYVLSDSDGEVASQDSDFDEDEASLDED

Chy4G079640 (gene) of Cucumber (hystrix) v1 genome