CuGenDBv2

Gene ID	Clc01G26150
Organism	Citrullus lanatus subsp. cordophanus (Watermelon (cordophanus) v2)
Description	Serine/threonine-protein kinase/endoribonuclease IRE1a
Genome location	ClcChr01:36212075..36214613
RNA-Seq Expression	Clc01G26150
Synteny	Clc01G26150
Gene Ontology terms	GO:0006397 - mRNA processing (biological process) GO:0006468 - protein phosphorylation (biological process) GO:0036498 - IRE1-mediated unfolded protein response (biological process) GO:0090502 - RNA phosphodiester bond hydrolysis, endonucleolytic (biological process) GO:0016021 - integral component of membrane (cellular component) GO:1990604 - IRE1-TRAF2-ASK1 complex (cellular component) GO:0004521 - endoribonuclease activity (molecular function) GO:0004674 - protein serine/threonine kinase activity (molecular function) GO:0004712 - protein serine/threonine/tyrosine kinase activity (molecular function) GO:0005524 - ATP binding (molecular function) GO:0008270 - zinc ion binding (molecular function) GO:0051082 - unfolded protein binding (molecular function) GO:0106310 - protein serine kinase activity (molecular function)
InterPro domains	IPR010513 - KEN domain IPR038357 - KEN domain superfamily

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0025572.1 pentatricopeptide repeat-containing protein [Cucumis melo var. makuwa]

6.3e-15

81.13

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Query:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD
        P    ELIGSV EGFDNYFASRFP+ L EVYRVISQYCREEEGF +YFKSHVD
Subjt:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD

TYK12446.1 serine/threonine-protein kinase/endoribonuclease IRE1a-like [Cucumis melo var. makuwa]

1.8e-14

79.25

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Query:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD
        P    ELIGSV EGFDNYFASRFP+ L EVYRVISQYCREEEGF +YFKSHV+
Subjt:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD

XP_004142048.1 serine/threonine-protein kinase/endoribonuclease IRE1a [Cucumis sativus]

1.8e-14

79.25

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Query:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD
        P    ELIGSV EGFDNYFASRFP+ L EVYRVISQYCREEEGF +YFKSHV+
Subjt:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD

XP_022950253.1 serine/threonine-protein kinase/endoribonuclease IRE1a-like isoform X1 [Cucurbita moschata]

1.8e-14

79.25

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Query:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD
        P    ELIGSV EGFDNYFASRFP+ L EVYRVISQYCREEEGF +YFKSHV+
Subjt:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD

XP_022977695.1 serine/threonine-protein kinase/endoribonuclease IRE1a-like isoform X2 [Cucurbita maxima]

1.8e-14

79.25

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Query:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD
        P    ELIGSV EGFDNYFASRFP+ L EVYRVISQYCREEEGF +YFKSHV+
Subjt:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD

TrEMBL top hits

e value

%identity

Alignment

A0A5A7SKB8 Non-specific serine/threonine protein kinase

3.0e-15

81.13

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Query:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD
        P    ELIGSV EGFDNYFASRFP+ L EVYRVISQYCREEEGF +YFKSHVD
Subjt:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD

A0A5D3CPU4 Non-specific serine/threonine protein kinase

8.8e-15

79.25

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Query:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD
        P    ELIGSV EGFDNYFASRFP+ L EVYRVISQYCREEEGF +YFKSHV+
Subjt:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD

A0A6J1GF96 Non-specific serine/threonine protein kinase

8.8e-15

79.25

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Query:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD
        P    ELIGSV EGFDNYFASRFP+ L EVYRVISQYCREEEGF +YFKSHV+
Subjt:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD

A0A6J1IJ73 Non-specific serine/threonine protein kinase

8.8e-15

79.25

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Query:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD
        P    ELIGSV EGFDNYFASRFP+ L EVYRVISQYCREEEGF +YFKSHV+
Subjt:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD

A0A6J1IN30 serine/threonine-protein kinase/endoribonuclease IRE1a-like isoform X2

8.8e-15

79.25

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Query:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD
        P    ELIGSV EGFDNYFASRFP+ L EVYRVISQYCREEEGF +YFKSHV+
Subjt:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHVD

SwissProt top hits

e value

%identity

Alignment

Q7XIT1 Serine/threonine-protein kinase/endoribonuclease IRE1

2.0e-08

58.14

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Query:  ELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYF
        EL+GS+ EGF  YF+SRFPK L +VY V+S++C++EE F +YF
Subjt:  ELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYF

Q93VJ2 Serine/threonine-protein kinase/endoribonuclease IRE1b

3.5e-08

53.85

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Query:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHV
        P    EL+GSV EGF+ YF+SRFPK L +VY V+  YC  EE F +Y K+ V
Subjt:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHV

Q9C5S2 Serine/threonine-protein kinase/endoribonuclease IRE1a

4.4e-11

63.46

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Query:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHV
        P    EL+G+V EGFD YFA RFPK L EVYRVIS +CREEE F +YFK  +
Subjt:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHV

Q9SF12 Inactive serine/threonine-protein kinase/endoribonuclease IRE1-like

1.2e-05

46.51

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Query:  ELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYF
        E++G V EG D +F +RFP  + E+Y  IS +C+ EE F +YF
Subjt:  ELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYF

Arabidopsis top hits

e value

%identity

Alignment

AT2G17520.1 Endoribonuclease/protein kinase IRE1-like

3.1e-12

63.46

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Query:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHV
        P    EL+G+V EGFD YFA RFPK L EVYRVIS +CREEE F +YFK  +
Subjt:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHV

AT3G11870.1 Endoribonuclease/protein kinase IRE1-like

8.7e-07

46.51

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Query:  ELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYF
        E++G V EG D +F +RFP  + E+Y  IS +C+ EE F +YF
Subjt:  ELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYF

AT5G24360.1 inositol requiring 1-1

2.5e-09

53.85

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Query:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHV
        P    EL+GSV EGF+ YF+SRFPK L +VY V+  YC  EE F +Y K+ V
Subjt:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHV

AT5G24360.2 inositol requiring 1-1

2.5e-09

53.85

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Query:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHV
        P    EL+GSV EGF+ YF+SRFPK L +VY V+  YC  EE F +Y K+ V
Subjt:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHV

AT5G24360.3 inositol requiring 1-1

2.5e-09

53.85

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Query:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHV
        P    EL+GSV EGF+ YF+SRFPK L +VY V+  YC  EE F +Y K+ V
Subjt:  PHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEEGFGEYFKSHV

Sequences

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CDS sequence

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ATGAGAGTCACTTCGCATCAATTTACTATCAATCTCGAGGTCAAAGTTTCGATCGTTTCCGGTTACGCTTCGTATATAACCCCAAATTTCTGTCGACCTGTGTCTGCACA
CAACCTGTTGGACAAAATTCCTTGGTTAGAATCAGGATTGGCCCAGCTTCATGAATTGGCCGCCCAAACTGCTGCTGCTGTGACCCCTAATCATCCTCACTATGCAACTG
AGCTCATAGGATCCGTTCATGAGGGATTTGATAACTACTTTGCTAGTCGGTTTCCAAAGCCCCTGCCTGAAGTATACAGAGTTATTAGCCAATACTGCAGGGAAGAGGAA
GGGTTTGGGGAGTACTTCAAAAGCCATGTGGATTAG

mRNA sequence

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Protein sequence

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MRVTSHQFTINLEVKVSIVSGYASYITPNFCRPVSAHNLLDKIPWLESGLAQLHELAAQTAAAVTPNHPHYATELIGSVHEGFDNYFASRFPKPLPEVYRVISQYCREEE
GFGEYFKSHVD

Clc01G26150 (gene) of Watermelon (cordophanus) v2 genome