CuGenDBv2

Gene ID	Clc06G16370
Organism	Citrullus lanatus subsp. cordophanus (Watermelon (cordophanus) v2)
Description	protein MIS12 homolog
Genome location	ClcChr06:27153385..27156457
RNA-Seq Expression	Clc06G16370
Synteny	Clc06G16370
Gene Ontology terms	GO:0000070 - mitotic sister chromatid segregation (biological process) GO:0034501 - protein localization to kinetochore (biological process) GO:0051301 - cell division (biological process) GO:0051382 - kinetochore assembly (biological process) GO:0000818 - nuclear MIS12/MIND complex (cellular component)
InterPro domains	IPR008685 - Centromere protein Mis12

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAA0058004.1 Centromere protein Mis12 [Cucumis melo var. makuwa]

7.9e-102

83.75

Show/hide

Query:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI
        MEGSKGE+VF+SLNLNPQLFINEALN VDDL+DDAFDFYQSQASAALKTEGSDRSQDLTLGIS+VRALVQLGLDKRLAMWEK+   + C   P       
Subjt:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI

Query:  EDESPGVTSISHDYDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGMEE
         DESPGVTSI+HD DVDLDTELD LRNKLSE RKENIVL+QELQALERQTASSNSQI+HFNEALQLYEQ+SVN+MFQEM+ TASELRAKIGK+KKR  EE
Subjt:  EDESPGVTSISHDYDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGMEE

Query:  AKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL
        AKL+KVEKVHTNGDISHHHNGFSNAKLDDIQEFL+DLK +
Subjt:  AKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL

KAA0058032.1 Centromere protein Mis12 [Cucumis melo var. makuwa]

5.1e-101

82.92

Show/hide

Query:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI
        MEGSKGE+VF+SLNLNPQLFINEALN VDDL+DDAFDFYQSQASA LKTEGSDRSQDLTLGIS+VRALVQLGLDKRLAMWEK+   + C   P       
Subjt:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI

Query:  EDESPGVTSISHDYDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGMEE
         DESPGVTSI+HD DVDLDTELD LRNKLSE RKENIVL+QELQALERQTASSNSQI+HFNEALQLYEQ+SVN+MFQEM+ TASELR+KIGK+KKR  EE
Subjt:  EDESPGVTSISHDYDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGMEE

Query:  AKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL
        AKL+KVEKVHTNGDISHHHNGFSNAKLDDIQEFL+DLK +
Subjt:  AKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL

KAG6589575.1 Protein MIS12-like protein, partial [Cucurbita argyrosperma subsp. sororia]

8.7e-101

83.06

Show/hide

Query:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI
        MEGSKGE VFDSLNLNPQLFINEALNIVDDL+DDAFDFYQ+QASA+LKTEGSDRSQDL LGISRVR  VQ GLDKRLAMWEK+   + C   P       
Subjt:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI

Query:  EDESPGVTSISHD--YDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGM
         DESP VTS+S D  YDVDLDTELDFLRNKLSE RKEN+VL+QELQALERQTASSNSQ+N FNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKR M
Subjt:  EDESPGVTSISHD--YDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGM

Query:  EEAKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL
        EE+KL+KVEK+HTNGDISHHH GFSNAKLDDIQEFLADLK L
Subjt:  EEAKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL

XP_023515499.1 protein MIS12 homolog isoform X2 [Cucurbita pepo subsp. pepo]

1.3e-101

83.47

Show/hide

Query:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI
        MEGSKGE VFDSLNLNPQLFINEALNIVDDL+DDAFDFYQ+QASA+LKTEGSDRSQDL+LGISRVR  VQ GLDKRLAMWEK+   + C   P       
Subjt:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI

Query:  EDESPGVTSISHD--YDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGM
         DESP VTS+S D  YDVDLDTELDFLRNKLSE RKEN+VL+QELQALERQTASSNSQ+N FNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKR M
Subjt:  EDESPGVTSISHD--YDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGM

Query:  EEAKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL
        EE+KL+KVEK+HTNGDISHHH GFSNAKLDDIQEFLADLKTL
Subjt:  EEAKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL

XP_038879945.1 protein MIS12 homolog [Benincasa hispida]

2.9e-104

86.25

Show/hide

Query:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI
        MEGSKGEAVFDSLNLNPQLFINEALNIVDDL+DDAF FYQSQASA LKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEK+   + C   P       
Subjt:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI

Query:  EDESPGVTSISHDYDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGMEE
         D+SPGVTSISHDYDV LDTELDFLRNKLSE RKENIVL+QELQALERQTA+SNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKR MEE
Subjt:  EDESPGVTSISHDYDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGMEE

Query:  AKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL
        +KL+KVEKVHTNGDISH+HNG SNAKLDDI+ FL DLKTL
Subjt:  AKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL

TrEMBL top hits

e value

%identity

Alignment

A0A5A7UQ95 Centromere protein Mis12

2.5e-101

82.92

Show/hide

Query:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI
        MEGSKGE+VF+SLNLNPQLFINEALN VDDL+DDAFDFYQSQASA LKTEGSDRSQDLTLGIS+VRALVQLGLDKRLAMWEK+   + C   P       
Subjt:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI

Query:  EDESPGVTSISHDYDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGMEE
         DESPGVTSI+HD DVDLDTELD LRNKLSE RKENIVL+QELQALERQTASSNSQI+HFNEALQLYEQ+SVN+MFQEM+ TASELR+KIGK+KKR  EE
Subjt:  EDESPGVTSISHDYDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGMEE

Query:  AKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL
        AKL+KVEKVHTNGDISHHHNGFSNAKLDDIQEFL+DLK +
Subjt:  AKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL

A0A5A7US57 Centromere protein Mis12

3.8e-102

83.75

Show/hide

Query:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI
        MEGSKGE+VF+SLNLNPQLFINEALN VDDL+DDAFDFYQSQASAALKTEGSDRSQDLTLGIS+VRALVQLGLDKRLAMWEK+   + C   P       
Subjt:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI

Query:  EDESPGVTSISHDYDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGMEE
         DESPGVTSI+HD DVDLDTELD LRNKLSE RKENIVL+QELQALERQTASSNSQI+HFNEALQLYEQ+SVN+MFQEM+ TASELRAKIGK+KKR  EE
Subjt:  EDESPGVTSISHDYDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGMEE

Query:  AKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL
        AKL+KVEKVHTNGDISHHHNGFSNAKLDDIQEFL+DLK +
Subjt:  AKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL

A0A6J1E0A1 protein MIS12 homolog

1.4e-99

82.23

Show/hide

Query:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI
        MEGSKGE VFDSLNLNPQLFINEALNIVDDL+DDAFDFYQ+QASA+LKTEGSDRSQDL LGISRVR  VQ GLDKRLAMWEK+   + C   P       
Subjt:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI

Query:  EDESPGVTSISHD--YDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGM
         DESP VTS+S D  YDVDLDTELDFLRNKLSE RKENIVL+QELQALERQ ASSNSQ+N FNEALQLYE+NSVNEMFQEMMGTASELRAKIGKLKKR M
Subjt:  EDESPGVTSISHD--YDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGM

Query:  EEAKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL
        EE+KL+KVEK+HTNGD SHHH GFSNAKLDDIQEFLADLK L
Subjt:  EEAKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL

A0A6J1JD43 protein MIS12 homolog isoform X1

3.3e-98

82.3

Show/hide

Query:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI
        MEGSKGE VFDSLNLNPQLFINEALNIVDDL+DDAFDFYQ+QASA+LKTEGSDRSQDL LGISRVR  VQ GLDKRLAMWEK+   + C   P       
Subjt:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI

Query:  EDESPGVTSISHD--YDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQ-EMMGTASELRAKIGKLKKRG
         DESP VTS+S D  YDVDLDTELDFLR  LSE RKENIVL+QELQALERQTASSNSQ+N FNEALQLYEQNSVNEMFQ EMMGTASELRAKIGKLKKR 
Subjt:  EDESPGVTSISHD--YDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQ-EMMGTASELRAKIGKLKKRG

Query:  MEEAKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL
        MEE+KL+KVEK+HTN DISHHH GFSNAKLDDIQEFLADLKTL
Subjt:  MEEAKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL

A0A6J1JME3 protein MIS12 homolog isoform X2

1.4e-99

82.64

Show/hide

Query:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI
        MEGSKGE VFDSLNLNPQLFINEALNIVDDL+DDAFDFYQ+QASA+LKTEGSDRSQDL LGISRVR  VQ GLDKRLAMWEK+   + C   P       
Subjt:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNI

Query:  EDESPGVTSISHD--YDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGM
         DESP VTS+S D  YDVDLDTELDFLR  LSE RKENIVL+QELQALERQTASSNSQ+N FNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKR M
Subjt:  EDESPGVTSISHD--YDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGM

Query:  EEAKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL
        EE+KL+KVEK+HTN DISHHH GFSNAKLDDIQEFLADLKTL
Subjt:  EEAKLSKVEKVHTNGDISHHHNGFSNAKLDDIQEFLADLKTL

SwissProt top hits

e value

%identity

Alignment

Q2V0Z5 Protein MIS12 homolog

2.4e-45

44.76

Show/hide

Query:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSD--RSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDK
        MEGSK EAVFDS+NLNPQ+FINEA+N V+D +D AFDFY   AS +LK +GSD  +SQ L+ GI+RVR L+   +D RL +WE +    FC   P   D 
Subjt:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSD--RSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDK

Query:  NIEDESPGVTSISHD--YDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKR
         +  +S   +S+  D  YD++LD ELD LR+KL+   K ++ L  ELQALER + S    +   NEAL+LY+++S++E+F+EM   ASELRA + +LK R
Subjt:  NIEDESPGVTSISHD--YDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKR

Query:  GMEEAKLSKVEKVHTNGDISHHHNGFS----NAKLDDIQEFLADLKTL
         M+ ++ +KV++      + +H   FS    + KL+D+++F A+L+ +
Subjt:  GMEEAKLSKVEKVHTNGDISHHHNGFS----NAKLDDIQEFLADLKTL

Arabidopsis top hits

e value

%identity

Alignment

AT5G35520.1 minichromosome instability 12 (mis12)-like

1.7e-46

44.76

Show/hide

Query:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSD--RSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDK
        MEGSK EAVFDS+NLNPQ+FINEA+N V+D +D AFDFY   AS +LK +GSD  +SQ L+ GI+RVR L+   +D RL +WE +    FC   P   D 
Subjt:  MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSD--RSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDK

Query:  NIEDESPGVTSISHD--YDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKR
         +  +S   +S+  D  YD++LD ELD LR+KL+   K ++ L  ELQALER + S    +   NEAL+LY+++S++E+F+EM   ASELRA + +LK R
Subjt:  NIEDESPGVTSISHD--YDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKR

Query:  GMEEAKLSKVEKVHTNGDISHHHNGFS----NAKLDDIQEFLADLKTL
         M+ ++ +KV++      + +H   FS    + KL+D+++F A+L+ +
Subjt:  GMEEAKLSKVEKVHTNGDISHHHNGFS----NAKLDDIQEFLADLKTL

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGGAAGGAAGTAAAGGCGAAGCAGTATTCGATTCACTGAATCTGAATCCGCAGCTCTTCATTAATGAAGCTCTCAATATTGTCGACGATTTGCTTGATGACGCTTTCGA
TTTCTATCAATCACAAGCATCGGCCGCCTTGAAGACCGAGGGCTCCGACAGATCCCAGGATCTTACCCTGGGAATATCGCGAGTCCGAGCGTTGGTCCAATTGGGTCTGG
ATAAGCGGTTGGCCATGTGGGAGAAGTTTTTCTTCTACTCTTTCTGTGATAAGGCTCCGGTGCCCAAGGATAAAAATATCGAAGATGAATCACCTGGTGTCACTTCAATA
AGTCATGACTATGACGTGGATCTGGATACAGAGTTAGATTTTTTGAGGAATAAGCTCTCTGAGGCCAGAAAAGAGAATATTGTATTGAGCCAAGAGCTACAAGCTTTGGA
AAGGCAAACTGCTTCCAGTAACTCCCAAATTAATCATTTCAACGAAGCATTACAACTATATGAGCAAAATTCTGTGAATGAGATGTTCCAGGAAATGATGGGAACTGCAT
CGGAGCTACGAGCGAAAATAGGAAAGCTGAAGAAAAGGGGGATGGAGGAAGCCAAGCTCAGTAAAGTAGAGAAGGTTCATACAAACGGAGACATCTCTCACCATCACAAT
GGTTTCTCTAATGCTAAGCTGGATGACATTCAAGAATTCTTAGCTGATTTGAAGACCCTTTGA

mRNA sequence

Show/hide mRNA sequence

Protein sequence

Show/hide protein sequence

MEGSKGEAVFDSLNLNPQLFINEALNIVDDLLDDAFDFYQSQASAALKTEGSDRSQDLTLGISRVRALVQLGLDKRLAMWEKFFFYSFCDKAPVPKDKNIEDESPGVTSI
SHDYDVDLDTELDFLRNKLSEARKENIVLSQELQALERQTASSNSQINHFNEALQLYEQNSVNEMFQEMMGTASELRAKIGKLKKRGMEEAKLSKVEKVHTNGDISHHHN
GFSNAKLDDIQEFLADLKTL

Clc06G16370 (gene) of Watermelon (cordophanus) v2 genome