CuGenDBv2

Gene ID	Clc11G20110
Organism	Citrullus lanatus subsp. cordophanus (Watermelon (cordophanus) v2)
Description	Niemann-Pick C1 protein isoform X1
Genome location	ClcChr11:30519143..30535128
RNA-Seq Expression	Clc11G20110
Synteny	Clc11G20110
Gene Ontology terms	GO:0006869 - lipid transport (biological process) GO:0016021 - integral component of membrane (cellular component) GO:0005319 - lipid transporter activity (molecular function)
InterPro domains	IPR000731 - Sterol-sensing domain IPR003392 - Protein patched/dispatched IPR004765 - NPC1-like IPR032190 - Niemann-Pick C1, N-terminal

Homology

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GenBank top hits

e value

%identity

Alignment

XP_008452964.1 PREDICTED: Niemann-Pick C1 protein isoform X1 [Cucumis melo]

0.0e+00

82.45

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Query:  MRLRLGFIALIYLLQVLCFILSYAERSNT----STNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQ
        MRLRLGFI  IYLLQVLCF+L YAE SNT    STNG SGEKHSEGYC MYGICAKRPDGKALNCPTGAPSVQ                           
Subjt:  MRLRLGFIALIYLLQVLCFILSYAERSNT----STNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQ

Query:  NLNPDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL
           PDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL
Subjt:  NLNPDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL

Query:  FESCKNVKFGTMNTRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK
        +ESCK+VKFGTMNTRAMQFIGADA+NFKEWFAFIGKQAGPGLPGSPYA+GFPSTV VSSGMKHMN SAYSCGDTSLGCSCGDCPSAPVCS+TATPVFHRK
Subjt:  FESCKNVKFGTMNTRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK

Query:  NSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR
         SCSVRIGSLKVKCVDFTLCILY IIASAFLGWSLFYRKSQKS SSGTKTMPNIMDG SLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR
Subjt:  NSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR

Query:  KYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKI
        KYG WVARNPTLVLISSLAIVLLLCLGL+RFKVETRPDKLWVGPGSKASQEKEFFD+HLAPFYRIEQIIIATVPD++HGKPPSILNDNNIKLLFDIQKKI
Subjt:  KYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKI

Query:  DGIRANYSGSSISLSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNN
        DGIRANYSG+SISLSDICLKPLDQECATQSVLQYFQMNPENVDNYGGV+HLEYCFQHYSSAD+CRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNN
Subjt:  DGIRANYSGSSISLSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNN

Query:  AINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVV
        AINKEGNESG AVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITIL+ S+  +F  I+      P+L+   +S  VLLGLSGVV
Subjt:  AINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVV

Query:  LVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP
        LVMLSVL SVGFFSAIGVKSTLIIMEVIPFLVLA         VGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP
Subjt:  LVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP

Query:  ACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISC
        ACRVFSMFA                                  ALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSS YAGSDK          
Subjt:  ACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISC

Query:  SSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI
                                    GITQR+PGLLARYMKEIHAPALSIW+VKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI
Subjt:  SSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI

Query:  SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS
        SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS
Subjt:  SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS

Query:  DGG-SCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQV
         GG SCGLNG+CKDCTT            CFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSV+LKDYENGVIQASSFRTYHTPLNKQV
Subjt:  DGG-SCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQV

Query:  DYINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGV
        DYINSMRAAQELSSR+SDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAI  +  + +       ++  S   S I +   + +  +LM         
Subjt:  DYINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGV

Query:  DNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSR
                               GVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSR
Subjt:  DNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSR

Query:  TEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS
        TEVFVVYYF +YLALVLLGFLHGLVFLPV+LSLFGPPSRCVFVEQQDNRPSTS
Subjt:  TEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS

XP_011654271.1 NPC intracellular cholesterol transporter 1 isoform X1 [Cucumis sativus]

0.0e+00

81.83

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Query:  MRLRLGFIALIYLLQVLCFILSYAERSNT----STNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQ
        MR+RLGFI  IYLLQVLCF+L YAE SNT    STNG SGEKHSEGYC MYGICAKRPDGKALNCPTGAPSVQ                           
Subjt:  MRLRLGFIALIYLLQVLCFILSYAERSNT----STNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQ

Query:  NLNPDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL
           PDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL
Subjt:  NLNPDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL

Query:  FESCKNVKFGTMNTRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK
        +ESCK+VK+GTMNTRAMQFIGADA+NFKEWFAFIGKQAGPGLPGSPYA+GFP T+ VSSGMKHMN SAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK
Subjt:  FESCKNVKFGTMNTRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK

Query:  NSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR
        NSCSV+IGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDG SLHSATR+KDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR
Subjt:  NSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR

Query:  KYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKI
        KYG WVARNPTLVLISSLAIVLLLC+GL+RFKVETRPDKLWVGPGSKASQEKEFFD+HLAPFYRIEQIIIATVPD++HGKPPSILNDNN+KLLFDIQKKI
Subjt:  KYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKI

Query:  DGIRANYSGSSISLSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNN
        DGIRANYSG SISLSDIC+KPLDQECATQSVLQYFQMNPENVDNYGGV+HLEYCFQHYSSAD+CRSAFEAPLDPSTALGG+SGNNYSEASAFLITYPVNN
Subjt:  DGIRANYSGSSISLSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNN

Query:  AINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVV
        AINKEGNESG AVAWEKAFIQLAKAELLTM QSQNLTLSFSSESSIEEELKRESTADVITIL+ S+  +F  I+      P+L+   +S  VLLGLSGVV
Subjt:  AINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVV

Query:  LVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP
        LVMLSVL SVGFFSAIGVKSTLIIMEVIPFLVLA         VGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP
Subjt:  LVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP

Query:  ACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISC
        ACRVFSMFA                                  ALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSS YAGSDK          
Subjt:  ACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISC

Query:  SSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI
                                    GITQ+NPGLLARYMKEIHAPALSIW+VKI+VISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI
Subjt:  SSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI

Query:  SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS
        SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS
Subjt:  SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS

Query:  -DGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQV
          GGSCGLNG+CKDCTT            CFLHSDL+GGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSV+LKDYENGVIQASSFRTYHTPLNKQV
Subjt:  -DGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQV

Query:  DYINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGV
        DYINSMRAAQELSSR+SDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAI  +  + +       ++  S   S I +   + +  +LM         
Subjt:  DYINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGV

Query:  DNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSR
                               GVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSR
Subjt:  DNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSR

Query:  TEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS
        TEVFVVYYF +YLALVLLGFLHGLVFLPV+LSLFGPPSRCVFVEQQDNRPSTS
Subjt:  TEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS

XP_031740283.1 NPC intracellular cholesterol transporter 1 isoform X2 [Cucumis sativus]

0.0e+00

81.85

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Query:  VLCFILSYAERSNT----STNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQNLNPDNLLSSKIQSL
        VLCF+L YAE SNT    STNG SGEKHSEGYC MYGICAKRPDGKALNCPTGAPSVQ                              PDNLLSSKIQSL
Subjt:  VLCFILSYAERSNT----STNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQNLNPDNLLSSKIQSL

Query:  CPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGLFESCKNVKFGTMNTR
        CPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL+ESCK+VK+GTMNTR
Subjt:  CPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGLFESCKNVKFGTMNTR

Query:  AMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVKCV
        AMQFIGADA+NFKEWFAFIGKQAGPGLPGSPYA+GFP T+ VSSGMKHMN SAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSV+IGSLKVKCV
Subjt:  AMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVKCV

Query:  DFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGAWVARNPTLVLI
        DFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDG SLHSATR+KDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYG WVARNPTLVLI
Subjt:  DFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGAWVARNPTLVLI

Query:  SSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKIDGIRANYSGSSISLS
        SSLAIVLLLC+GL+RFKVETRPDKLWVGPGSKASQEKEFFD+HLAPFYRIEQIIIATVPD++HGKPPSILNDNN+KLLFDIQKKIDGIRANYSG SISLS
Subjt:  SSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKIDGIRANYSGSSISLS

Query:  DICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAVAW
        DIC+KPLDQECATQSVLQYFQMNPENVDNYGGV+HLEYCFQHYSSAD+CRSAFEAPLDPSTALGG+SGNNYSEASAFLITYPVNNAINKEGNESG AVAW
Subjt:  DICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAVAW

Query:  EKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVVLVMLSVLGSVGFFSA
        EKAFIQLAKAELLTM QSQNLTLSFSSESSIEEELKRESTADVITIL+ S+  +F  I+      P+L+   +S  VLLGLSGVVLVMLSVL SVGFFSA
Subjt:  EKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVVLVMLSVLGSVGFFSA

Query:  IGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAGLTICP
        IGVKSTLIIMEVIPFLVLA         VGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFA      
Subjt:  IGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAGLTICP

Query:  LQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISCSSFLFKYACPDLLVH
                                    ALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSS YAGSDK                         
Subjt:  LQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISCSSFLFKYACPDLLVH

Query:  FIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFVVK
                     GITQ+NPGLLARYMKEIHAPALSIW+VKI+VISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFVVK
Subjt:  FIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFVVK

Query:  NYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS-DGGSCGLNGICKDC
        NYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS  GGSCGLNG+CKDC
Subjt:  NYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS-DGGSCGLNGICKDC

Query:  TTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSSR
        TT            CFLHSDL+GGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSV+LKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSSR
Subjt:  TTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSSR

Query:  ISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIPN
        +SDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAI  +  + +       ++  S   S I +   + +  +LM                        
Subjt:  ISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIPN

Query:  YLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLAL
                GVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYF +YLAL
Subjt:  YLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLAL

Query:  VLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS
        VLLGFLHGLVFLPV+LSLFGPPSRCVFVEQQDNRPSTS
Subjt:  VLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS

XP_038897902.1 NPC intracellular cholesterol transporter 1-like isoform X1 [Benincasa hispida]

0.0e+00

83.11

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Query:  LQVLCFILSYAERSNT----STNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQNLNPDNLLSSKIQ
        + VLCF  +YAERSNT    STNGIS EKHSEGYCAMYGICAKR DGKALNCPTGAPSVQ                              PDNLLSSKIQ
Subjt:  LQVLCFILSYAERSNT----STNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQNLNPDNLLSSKIQ

Query:  SLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGLFESCKNVKFGTMN
        SLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVD IDYYVADAFGEGLFESCK+VKFGTMN
Subjt:  SLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGLFESCKNVKFGTMN

Query:  TRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVK
        TRAMQFIGADA+NFKEWFAFIGKQAGPGLPGSPYA+GFPSTV VSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVK
Subjt:  TRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVK

Query:  CVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGAWVARNPTLV
        CVDFTLCILYIIIASAFL WS FYRKS+KSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYG WVARNPTLV
Subjt:  CVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGAWVARNPTLV

Query:  LISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKIDGIRANYSGSSIS
        LISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDT+HGKPPSILNDNNIKLLFDIQKK+D IR NYSGSS+S
Subjt:  LISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKIDGIRANYSGSSIS

Query:  LSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAV
        LSDICLKPLDQECATQSVLQYFQMN ENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNN+SEASAFLITYPVNNAINKEGNESGRAV
Subjt:  LSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAV

Query:  AWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVVLVMLSVLGSVGFF
        AWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITIL+ S+  +F  I+      P+L+   +S  VLLGLSGVVLVMLSVLGSVGFF
Subjt:  AWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVVLVMLSVLGSVGFF

Query:  SAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAGLTI
        SAIGVKSTLIIMEVIPFLVLA         VGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFA    
Subjt:  SAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAGLTI

Query:  CPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISCSSFLFKYACPDLL
                                      ALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDK                       
Subjt:  CPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISCSSFLFKYACPDLL

Query:  VHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFV
                       GITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFV
Subjt:  VHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFV

Query:  VKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSSDGGSCGLNGICKD
        VKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSSDGGSCGLNG+CKD
Subjt:  VKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSSDGGSCGLNGICKD

Query:  CTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSS
        CTT            CFLHSDLHGGRPST QFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELS 
Subjt:  CTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSS

Query:  RISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIP
        RISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAI  +  + +       ++  S   S I +   + +  +LM                       
Subjt:  RISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIP

Query:  NYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLA
                 GVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQ+YLA
Subjt:  NYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLA

Query:  LVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS
        LVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS
Subjt:  LVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS

XP_038897903.1 NPC intracellular cholesterol transporter 1-like isoform X2 [Benincasa hispida]

0.0e+00

83.26

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Query:  MRLRLGFIALIYLLQVLCFILSYAERSNT----STNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQ
        MR RLGFI LIYLLQVLCF  +YAERSNT    STNGIS EKHSEGYCAMYGICAKR DGKALNCPTGAPSVQ                           
Subjt:  MRLRLGFIALIYLLQVLCFILSYAERSNT----STNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQ

Query:  NLNPDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL
           PDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVD IDYYVADAFGEGL
Subjt:  NLNPDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL

Query:  FESCKNVKFGTMNTRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK
        FESCK+VKFGTMNTRAMQFIGADA+NFKEWFAFIGKQAGPGLPGSPYA+GFPSTV VSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK
Subjt:  FESCKNVKFGTMNTRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK

Query:  NSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR
        NSCSVRIGSLKVKCVDFTLCILYIIIASAFL WS FYRKS+KSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR
Subjt:  NSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR

Query:  KYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKI
        KYG WVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDT+HGKPPSILNDNNIKLLFDIQKK+
Subjt:  KYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKI

Query:  DGIRANYSGSSISLSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNN
        D IR NYSGSS+SLSDICLKPLDQECATQSVLQYFQMN ENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNN+SEASAFLITYPVNN
Subjt:  DGIRANYSGSSISLSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNN

Query:  AINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVV
        AINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITIL+ S+  +F  I+      P+L+   +S  VLLGLSGVV
Subjt:  AINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVV

Query:  LVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP
        LVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLA         VGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP
Subjt:  LVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP

Query:  ACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISC
        ACRVFSMFA                                  ALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDK          
Subjt:  ACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISC

Query:  SSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI
                                    GITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI
Subjt:  SSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI

Query:  SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS
        SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS
Subjt:  SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS

Query:  DGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVD
        DGGSCGLNG+CKDCTT            CFLHSDLHGGRPST QFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVD
Subjt:  DGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVD

Query:  YINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVD
        YINSMRAAQELS RISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAI  +  + +       ++  S   S I +   + +  +LM          
Subjt:  YINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVD

Query:  NDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRT
                              GVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRT
Subjt:  NDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRT

Query:  EVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS
        EVFVVYYFQ+YLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS
Subjt:  EVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS

TrEMBL top hits

e value

%identity

Alignment

A0A0A0L4L2 SSD domain-containing protein

0.0e+00

81.83

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Query:  MRLRLGFIALIYLLQVLCFILSYAERSNT----STNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQ
        MR+RLGFI  IYLLQVLCF+L YAE SNT    STNG SGEKHSEGYC MYGICAKRPDGKALNCPTGAPSVQ                           
Subjt:  MRLRLGFIALIYLLQVLCFILSYAERSNT----STNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQ

Query:  NLNPDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL
           PDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL
Subjt:  NLNPDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL

Query:  FESCKNVKFGTMNTRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK
        +ESCK+VK+GTMNTRAMQFIGADA+NFKEWFAFIGKQAGPGLPGSPYA+GFP T+ VSSGMKHMN SAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK
Subjt:  FESCKNVKFGTMNTRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK

Query:  NSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR
        NSCSV+IGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDG SLHSATR+KDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR
Subjt:  NSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR

Query:  KYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKI
        KYG WVARNPTLVLISSLAIVLLLC+GL+RFKVETRPDKLWVGPGSKASQEKEFFD+HLAPFYRIEQIIIATVPD++HGKPPSILNDNN+KLLFDIQKKI
Subjt:  KYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKI

Query:  DGIRANYSGSSISLSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNN
        DGIRANYSG SISLSDIC+KPLDQECATQSVLQYFQMNPENVDNYGGV+HLEYCFQHYSSAD+CRSAFEAPLDPSTALGG+SGNNYSEASAFLITYPVNN
Subjt:  DGIRANYSGSSISLSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNN

Query:  AINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVV
        AINKEGNESG AVAWEKAFIQLAKAELLTM QSQNLTLSFSSESSIEEELKRESTADVITIL+ S+  +F  I+      P+L+   +S  VLLGLSGVV
Subjt:  AINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVV

Query:  LVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP
        LVMLSVL SVGFFSAIGVKSTLIIMEVIPFLVLA         VGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP
Subjt:  LVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP

Query:  ACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISC
        ACRVFSMFA                                  ALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSS YAGSDK          
Subjt:  ACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISC

Query:  SSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI
                                    GITQ+NPGLLARYMKEIHAPALSIW+VKI+VISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI
Subjt:  SSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI

Query:  SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS
        SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS
Subjt:  SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS

Query:  -DGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQV
          GGSCGLNG+CKDCTT            CFLHSDL+GGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSV+LKDYENGVIQASSFRTYHTPLNKQV
Subjt:  -DGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQV

Query:  DYINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGV
        DYINSMRAAQELSSR+SDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAI  +  + +       ++  S   S I +   + +  +LM         
Subjt:  DYINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGV

Query:  DNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSR
                               GVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSR
Subjt:  DNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSR

Query:  TEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS
        TEVFVVYYF +YLALVLLGFLHGLVFLPV+LSLFGPPSRCVFVEQQDNRPSTS
Subjt:  TEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS

A0A1S3BV25 Niemann-Pick C1 protein isoform X1

0.0e+00

82.45

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Query:  MRLRLGFIALIYLLQVLCFILSYAERSNT----STNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQ
        MRLRLGFI  IYLLQVLCF+L YAE SNT    STNG SGEKHSEGYC MYGICAKRPDGKALNCPTGAPSVQ                           
Subjt:  MRLRLGFIALIYLLQVLCFILSYAERSNT----STNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQ

Query:  NLNPDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL
           PDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL
Subjt:  NLNPDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL

Query:  FESCKNVKFGTMNTRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK
        +ESCK+VKFGTMNTRAMQFIGADA+NFKEWFAFIGKQAGPGLPGSPYA+GFPSTV VSSGMKHMN SAYSCGDTSLGCSCGDCPSAPVCS+TATPVFHRK
Subjt:  FESCKNVKFGTMNTRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK

Query:  NSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR
         SCSVRIGSLKVKCVDFTLCILY IIASAFLGWSLFYRKSQKS SSGTKTMPNIMDG SLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR
Subjt:  NSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR

Query:  KYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKI
        KYG WVARNPTLVLISSLAIVLLLCLGL+RFKVETRPDKLWVGPGSKASQEKEFFD+HLAPFYRIEQIIIATVPD++HGKPPSILNDNNIKLLFDIQKKI
Subjt:  KYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKI

Query:  DGIRANYSGSSISLSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNN
        DGIRANYSG+SISLSDICLKPLDQECATQSVLQYFQMNPENVDNYGGV+HLEYCFQHYSSAD+CRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNN
Subjt:  DGIRANYSGSSISLSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNN

Query:  AINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVV
        AINKEGNESG AVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITIL+ S+  +F  I+      P+L+   +S  VLLGLSGVV
Subjt:  AINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVV

Query:  LVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP
        LVMLSVL SVGFFSAIGVKSTLIIMEVIPFLVLA         VGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP
Subjt:  LVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP

Query:  ACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISC
        ACRVFSMFA                                  ALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSS YAGSDK          
Subjt:  ACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISC

Query:  SSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI
                                    GITQR+PGLLARYMKEIHAPALSIW+VKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI
Subjt:  SSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI

Query:  SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS
        SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS
Subjt:  SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS

Query:  DGG-SCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQV
         GG SCGLNG+CKDCTT            CFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSV+LKDYENGVIQASSFRTYHTPLNKQV
Subjt:  DGG-SCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQV

Query:  DYINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGV
        DYINSMRAAQELSSR+SDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAI  +  + +       ++  S   S I +   + +  +LM         
Subjt:  DYINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGV

Query:  DNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSR
                               GVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSR
Subjt:  DNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSR

Query:  TEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS
        TEVFVVYYF +YLALVLLGFLHGLVFLPV+LSLFGPPSRCVFVEQQDNRPSTS
Subjt:  TEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS

A0A6J1F8S5 Niemann-Pick C1 protein-like isoform X2

0.0e+00

80.68

Show/hide

Query:  LQVLCFILSYAERSN----TSTNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQNLNPDNLLSSKIQ
        ++VL F+L+YAERSN     STNG SGEKHSEGYC MYGIC KRPDGK LNCPTG PSVQ                              PDNLLSSKIQ
Subjt:  LQVLCFILSYAERSN----TSTNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQNLNPDNLLSSKIQ

Query:  SLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGLFESCKNVKFGTMN
        SLCPTITGNVCCTE+QFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVN+SLTVDAIDYYVADAFGEGLFESCK+VKFGTMN
Subjt:  SLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGLFESCKNVKFGTMN

Query:  TRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVK
        TRAMQFIGA AQNFKEWFAFIGK+A P +PGSPYA+GFPST+  SSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSST+TPVFHRKNSCSVRIGSLKVK
Subjt:  TRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVK

Query:  CVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGAWVARNPTLV
        CVDF LCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYG WVARNPTLV
Subjt:  CVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGAWVARNPTLV

Query:  LISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKIDGIRANYSGSSIS
        LISSLAIVLLLCLGLIRFKVETRP+KLWVGPGS+ASQEKEFFD HLAPFYRIEQIIIATVPDT HGKPPSILNDNN+KLLF IQKKIDGIRANYSGSS+S
Subjt:  LISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKIDGIRANYSGSSIS

Query:  LSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAV
        L+DICLKPLD++CATQSVLQYFQMNPEN DNYGGVEHLEYCF+HYSSAD+CRSAF+APLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAV
Subjt:  LSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAV

Query:  AWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVVLVMLSVLGSVGFF
        AWEKAFIQLAK ELLTMVQSQNLTLSFSSESSIEEELKRESTADVITIL+ S+  +F  I+      P+L+   +S  VLLGLSGVVLVMLSVLGSVGFF
Subjt:  AWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVVLVMLSVLGSVGFF

Query:  SAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAGLTI
        SAIGVKSTLIIMEVIPFLVLA         VGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFA    
Subjt:  SAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAGLTI

Query:  CPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISCSSFLFKYACPDLL
                                      ALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIK+SGYAGSDK                       
Subjt:  CPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISCSSFLFKYACPDLL

Query:  VHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFV
                       GITQRNPGLLARYMKEIHAP LSIW VKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIG PVYFV
Subjt:  VHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFV

Query:  VKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSSDGGSCGLNGICKD
        VKNYNYSS+SRQTNQLCSISQCDS+SLLNEIAKASLIPESS+IAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQ PCC +S+GGSCGLNG+CKD
Subjt:  VKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSSDGGSCGLNGICKD

Query:  CTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSS
        CTT            CFLHSDLHGGRPST QFKEKLPWFLSALPSADCAKGGHGAYTSSVELK YENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSS
Subjt:  CTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSS

Query:  RISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIP
        R+SDSLKIE+FPYSVFYMFFEQYLNIWRTALINLAIAI  +  + +       ++  S   S I +   + +  +LM                       
Subjt:  RISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIP

Query:  NYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLA
                 GVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGD++QRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYF+MYLA
Subjt:  NYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLA

Query:  LVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS
        LVLLGFLHGLVFLPV+LSL GPPSRCVFVEQQDNRPSTS
Subjt:  LVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS

A0A6J1FF18 Niemann-Pick C1 protein-like isoform X1

0.0e+00

80.92

Show/hide

Query:  MRLRLGFIALIYLLQVLCFILSYAERSN----TSTNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQ
        MRLRLGFIA IYLLQVL F+L+YAERSN     STNG SGEKHSEGYC MYGIC KRPDGK LNCPTG PSVQ                           
Subjt:  MRLRLGFIALIYLLQVLCFILSYAERSN----TSTNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQ

Query:  NLNPDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL
           PDNLLSSKIQSLCPTITGNVCCTE+QFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVN+SLTVDAIDYYVADAFGEGL
Subjt:  NLNPDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL

Query:  FESCKNVKFGTMNTRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK
        FESCK+VKFGTMNTRAMQFIGA AQNFKEWFAFIGK+A P +PGSPYA+GFPST+  SSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSST+TPVFHRK
Subjt:  FESCKNVKFGTMNTRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK

Query:  NSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR
        NSCSVRIGSLKVKCVDF LCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR
Subjt:  NSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR

Query:  KYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKI
        KYG WVARNPTLVLISSLAIVLLLCLGLIRFKVETRP+KLWVGPGS+ASQEKEFFD HLAPFYRIEQIIIATVPDT HGKPPSILNDNN+KLLF IQKKI
Subjt:  KYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKI

Query:  DGIRANYSGSSISLSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNN
        DGIRANYSGSS+SL+DICLKPLD++CATQSVLQYFQMNPEN DNYGGVEHLEYCF+HYSSAD+CRSAF+APLDPSTALGGYSGNNYSEASAFLITYPVNN
Subjt:  DGIRANYSGSSISLSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNN

Query:  AINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVV
        AINKEGNESGRAVAWEKAFIQLAK ELLTMVQSQNLTLSFSSESSIEEELKRESTADVITIL+ S+  +F  I+      P+L+   +S  VLLGLSGVV
Subjt:  AINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVV

Query:  LVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP
        LVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLA         VGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP
Subjt:  LVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP

Query:  ACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISC
        ACRVFSMFA                                  ALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIK+SGYAGSDK          
Subjt:  ACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISC

Query:  SSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI
                                    GITQRNPGLLARYMKEIHAP LSIW VKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI
Subjt:  SSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI

Query:  SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS
        SEHLRIG PVYFVVKNYNYSS+SRQTNQLCSISQCDS+SLLNEIAKASLIPESS+IAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQ PCC +S
Subjt:  SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS

Query:  DGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVD
        +GGSCGLNG+CKDCTT            CFLHSDLHGGRPST QFKEKLPWFLSALPSADCAKGGHGAYTSSVELK YENGVIQASSFRTYHTPLNKQVD
Subjt:  DGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVD

Query:  YINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVD
        YINSMRAAQELSSR+SDSLKIE+FPYSVFYMFFEQYLNIWRTALINLAIAI  +  + +       ++  S   S I +   + +  +LM          
Subjt:  YINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVD

Query:  NDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRT
                              GVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGD++QRMKEALSTMGASVLSGITLTKLVGVLVLCFSRT
Subjt:  NDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRT

Query:  EVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS
        EVFVVYYF+MYLALVLLGFLHGLVFLPV+LSL GPPSRCVFVEQQDNRPSTS
Subjt:  EVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS

A0A6J1IFN2 Niemann-Pick C1 protein-like isoform X1

0.0e+00

80.51

Show/hide

Query:  MRLRLGFIALIYLLQVLCFILSYAERSN----TSTNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQ
        MRLRLGFIA IYLLQVL F+L+YAERSN     STNG SGEKHSEGYC MYGIC KRPDGK LNCPTG PSVQ                           
Subjt:  MRLRLGFIALIYLLQVLCFILSYAERSN----TSTNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQ

Query:  NLNPDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL
           PD+LLSSKIQSLCPTITGNVCCTE+QFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVN+SLTVDAIDYYVADAFGEGL
Subjt:  NLNPDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGL

Query:  FESCKNVKFGTMNTRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK
        FESCK+VKFGTMNTRAMQFIGA AQNFKEWFAFIGK+A P +PGSPYA+GFPST+  SSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK
Subjt:  FESCKNVKFGTMNTRAMQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRK

Query:  NSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR
        NSCSVR+GSLKVKCVDF LCILYIIIASAFLGWSLF+RKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR
Subjt:  NSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYR

Query:  KYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKI
        KYG WVARNPTLVLISSLA VLLLCLGLIRFKVETRP+KLWVGPGS+ASQEKEFFD HLAPFYRIEQIIIATVPDT HGKPPSILNDNN+KLLF IQKKI
Subjt:  KYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKI

Query:  DGIRANYSGSSISLSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNN
        DGIRANYSGSSISLSDICLKPLD +CATQSVLQYFQMNPEN DNYGGVEHLEYCF+HYSSAD+CRSAF+APLDPSTALGGYSGNNYSEASAFLITYPVNN
Subjt:  DGIRANYSGSSISLSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNN

Query:  AINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVV
        AINKEGNESGRAVAWEKAFIQLAK ELLTMVQSQNLTL+FSSESSIEEELKRESTADVITIL+ S+  +F  I+      PNL+   +S  VLLGLSGVV
Subjt:  AINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVV

Query:  LVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP
        LVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLA         VGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP
Subjt:  LVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMP

Query:  ACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISC
        ACRVFSMFA                                  ALAVLLDFLLQVTAFVALI FDFLRTEDKRVDCFPCIK+SGYAGSDK          
Subjt:  ACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISC

Query:  SSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI
                                    GITQRNPGLLARYMKEIHAP LSIW VKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI
Subjt:  SSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNI

Query:  SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS
        SEHLRIG PVYFVVKNYNYSS+SRQTNQLCSISQCDS+SLLNEIAKASLIPESS+IAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQ PCC +S
Subjt:  SEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSS

Query:  DGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVD
        +GGSCGLNG+CKDCTT            CFLHSDLHGGRPST QFKEKLPWFLSALPSADCAKGGHGAYTSSVELK YENGVIQASSFRTYHTPLNKQVD
Subjt:  DGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVD

Query:  YINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVD
        YINSMRAAQELSSR+SDSLKIE+FPYSVFYMFFEQYLNIWRTALINLAIAI  +  + +       ++  S   S I +   + +  +LM          
Subjt:  YINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVD

Query:  NDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRT
                              GVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAF VSSGD++QRMKEALSTMGASVLSGITLTKLVGVLVLCFSRT
Subjt:  NDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRT

Query:  EVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS
        EVFVVYYF+MYLALVLLGFLHGLVFLPV+LSL GP SRCVF+EQQDN+PSTS
Subjt:  EVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTS

SwissProt top hits

e value

%identity

Alignment

O15118 NPC intracellular cholesterol transporter 1

7.8e-166

32.66

Show/hide

Query:  IQSLCP-TITGNV--CCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLT------VDAIDYYVADAFGEGLFE
        +Q LCP    GNV  CC  +Q  TL+  +   + FL  CP+C  N LNLFCELTCSP QS F+NVT+     + +T      V  + YYV  +F   ++ 
Subjt:  IQSLCP-TITGNV--CCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLT------VDAIDYYVADAFGEGLFE

Query:  SCKNVKFGTMNTRAMQFI---GADAQNFKEWFAFIGKQAGPGLPG--SPYAMGFPSTVPVSSGMKHMNVSAYSCGDT----SLGCSCGDCPSAPVCSSTA
        +C++V+  + N +A+  +    ADA N   W  ++  +     P   +P    FP       GM+ MN +   C ++    +  CSC DC  + VC    
Subjt:  SCKNVKFGTMNTRAMQFI---GADAQNFKEWFAFIGKQAGPGLPG--SPYAMGFPSTVPVSSGMKHMNVSAYSCGDT----SLGCSCGDCPSAPVCSSTA

Query:  TPVFHRKNSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQG
         P         + + ++ V      +  L +   + F  W   YRK +   S  T    NI    +       K E+     +  A            +G
Subjt:  TPVFHRKNSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQG

Query:  YMSNFYRKYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPP----------S
         +   + ++G++  RNP  V+  SL  +     GL+  +V T P  LW  P S+A  EKE+FD H  PF+R EQ+II       H   P           
Subjt:  YMSNFYRKYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPP----------S

Query:  ILNDNNIKLLFDIQKKIDGIRANYSGSSISLSDICLKPL---DQECATQSVLQYFQMNPENVDNYGGVE---------HLEYCFQHYSSA-------DNC
         L+   +  + D+Q  I+ I A+Y   +++L DICL PL   +  C   SVL YFQ +   +D+  G +         H  YC +  +S        D C
Subjt:  ILNDNNIKLLFDIQKKIDGIRANYSGSSISLSDICLKPL---DQECATQSVLQYFQMNPENVDNYGGVE---------HLEYCFQHYSSA-------DNC

Query:  RSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVA
           F  P+ P   LGGY   NY+ A+A +IT+PVNN  N +  +  RA AWEK FI   K       ++ NLT+SF++E SIE+EL RES +DV T+++ 
Subjt:  RSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVA

Query:  SHRAIFPLIA-----NSPCLPNLTADKLSCNVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQS
        S+  +F  I+        C   L   K+S    LG++G+++V+ SV  S+G FS IG+  TLI++EVIPFLVLA         VGVDN+ ILV A +R  
Subjt:  SHRAIFPLIA-----NSPCLPNLTADKLSCNVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQS

Query:  --VELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAF
              L+ ++   L EV PS+ L+S SE +AF +G+   MPA   FS+FAG                                  LAV +DFLLQ+T F
Subjt:  --VELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAF

Query:  VALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISCSSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIV
        V+L+  D  R E  R+D F C++     G++ G+      SC                                     L R+ K  ++P L    ++ +
Subjt:  VALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISCSSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIV

Query:  VISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAK
        VI+IFVG    SIA+  +++ GL+Q + +P DSY+  YF +IS++L  GPPVYFV++  +  + S+  N +C    C++DSL+ +I  A+ +   + I  
Subjt:  VISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAK

Query:  PAASWLDDYLVWISPEAFGCCR-KFTNGSYCPPDDQPPCCTSSDGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALP
          +SW+DDY  W+ P++  CCR       +C      P C             C+  T         PE            RP    F   LP FLS  P
Subjt:  PAASWLDDYLVWISPEAFGCCR-KFTNGSYCPPDDQPPCCTSSDGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALP

Query:  SADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSSRISDSLKI-----EIFPYSVFYMFFEQYLNIWRTALINLAI---
        +  C KGGH AY+S+V +       + A+ F TYHT L    D+I++++ A+ ++S +++++ I      +FPYSVFY+F+EQYL I    + NL +   
Subjt:  SADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSSRISDSLKI-----EIFPYSVFYMFFEQYLNIWRTALINLAI---

Query:  AIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVE
        AI L+  +L+  E    V++                                  C +  +  +  +       GVM +  I LNA+S+VNLVMS GI+VE
Subjt:  AIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVE

Query:  FCVHLTHAFSVS-SGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGP
        FC H+T AF+VS  G R +R +EAL+ MG+SV SGITLTK  G++VL F+++++F ++YF+MYLA+VLLG  HGL+FLPV+LS  GP
Subjt:  FCVHLTHAFSVS-SGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGP

O35604 NPC intracellular cholesterol transporter 1

2.5e-164

32.57

Show/hide

Query:  IQSLCPTI---TGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSV------LKVNNSLTVDAIDYYVADAFGEGLFE
        +Q LCP +     ++CC  QQ  TL+S +   + FL  CP+C  N + LFCELTCSP+QS F+NVT+           N   V  ++Y+V  +F   ++ 
Subjt:  IQSLCPTI---TGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSV------LKVNNSLTVDAIDYYVADAFGEGLFE

Query:  SCKNVKFGTMNTRAMQFI-GADAQ--NFKEWFAFI-GKQAGPGLPGSPYAMGFPSTVPVSS-----GMKHMNVSAYSCGDT----SLGCSCGDCPSAPVC
        +C++V+  + N +A+  + G DA+  N   W  ++  K  G     +P+ +     +PV S     GM+ M  +   C ++    +  CSC DC  + VC
Subjt:  SCKNVKFGTMNTRAMQFI-GADAQ--NFKEWFAFI-GKQAGPGLPGSPYAMGFPSTVPVSS-----GMKHMNVSAYSCGDT----SLGCSCGDCPSAPVC

Query:  SSTATPVFHRKNSCSVRIGSLKVKCVDFTLCILYIIIASAFLG--WSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQ
             P          RI  L    V   + + Y+     F G   +++  + +   S  T    NI    S++S+   K E+     L  A        
Subjt:  SSTATPVFHRKNSCSVRIGSLKVKCVDFTLCILYIIIASAFLG--WSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQ

Query:  LSVVQGYMSNFYRKYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPP-----
               +   + K+GA+  RNPT ++  SLA + +   GL+  +V T P +LW  P S+A  EKE+FD H  PF+R EQ+II     ++H   P     
Subjt:  LSVVQGYMSNFYRKYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPP-----

Query:  -----SILNDNNIKLLFDIQKKIDGIRANYSGSSISLSDICLKPL---DQECATQSVLQYFQMNPENVDNYGGVE---------HLEYCFQHYSSADN--
               LN   +  + D+Q  I+ I A+Y+  +++L DIC+ PL   ++ C   SVL YFQ +   +D+  G +         H  YC +  +S ++  
Subjt:  -----SILNDNNIKLLFDIQKKIDGIRANYSGSSISLSDICLKPL---DQECATQSVLQYFQMNPENVDNYGGVE---------HLEYCFQHYSSADN--

Query:  -----CRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADV
             C   F  P+ P   LGGY   NY+ A+A +IT+PVNN  N +     RA AWEK FI   K       ++ NLT+SF++E SIE+EL RES +DV
Subjt:  -----CRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADV

Query:  ITILVASHRAIFPLIANS-----PCLPNLTADKLSCNVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVH
         T+++ S+  +F  I+ +      C   L   K+S    LG++G+++V+ SV  S+G FS +G+  TLI++EVIPFLVLA         VGVDN+ ILV 
Subjt:  ITILVASHRAIFPLIANS-----PCLPNLTADKLSCNVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVH

Query:  AVKRQS--VELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFL
          +R     E  L+ ++   L EV P++ L+S SE  AF  G+   MPA   FS+FAG                                  +AVL+DFL
Subjt:  AVKRQS--VELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFL

Query:  LQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISCSSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSI
        LQ+T FV+L+  D  R E   +D   C++    A   +GS      +  S+LF                                  R+ K   AP L  
Subjt:  LQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISCSSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSI

Query:  WVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFVV-KNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIP
          ++ +V+++FVG    S+A+  +++ GL+Q + +P DSY+  YF +++++L  GPPVYFV+ + YNYSS   Q N +C    CD+DSL+ +I  A+ + 
Subjt:  WVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFVV-KNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIP

Query:  ESSFIAKPAASWLDDYLVWISPEAFGCCRKF-TNGSYCPPDDQPPCCTSSDGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLP
          + +    +SW+DDY  W+SP++  CCR +     +C      P C             C+  T         PE            RP   +F + LP
Subjt:  ESSFIAKPAASWLDDYLVWISPEAFGCCRKF-TNGSYCPPDDQPPCCTSSDGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLP

Query:  WFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSSRISDSLK-----IEIFPYSVFYMFFEQYLNIWRTALI
         FLS  P+  C KGGH AY S+V +   ++  I A+ F TYHT L    DY ++M+ A+ ++S I+++++       +FPYSVFY+F+EQYL I    + 
Subjt:  WFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSSRISDSLK-----IEIFPYSVFYMFFEQYLNIWRTALI

Query:  NLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVG
        NL++++               + +V+  V G E+  +S++                  C +  +  +  +       GVM +  I LNA+S+VNLVMS G
Subjt:  NLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVG

Query:  IAVEFCVHLTHAFSVSS-GDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGP
        I+VEFC H+T AF++S+ G R  R +EAL+ MG+SV SGITLTK  G++VL F+++++F ++YF+MYLA+VLLG  HGL+FLPV+LS  GP
Subjt:  IAVEFCVHLTHAFSVSS-GDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGP

P56941 NPC intracellular cholesterol transporter 1

1.3e-165

32.54

Show/hide

Query:  IQSLCP-TITGNV--CCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLT------VDAIDYYVADAFGEGLFE
        +Q LCP    GNV  CC  QQ  TL+  +   + FL  CP+C  N +NLFCELTCSP QS F+NVT+     + +T      V  ++YYV + F   ++ 
Subjt:  IQSLCP-TITGNV--CCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLT------VDAIDYYVADAFGEGLFE

Query:  SCKNVKFGTMNTRAMQFI-GADAQ--NFKEWFAFIGKQAGPGLPG--SPYAMGFPSTVPVSSGMKHMNVSAYSCGDT----SLGCSCGDCPSAPVCSSTA
        +C++V+  + N +A+  + G +AQ  N   W  ++  +     P   +P     P     + GM+ MN +   C ++    +  CSC DC  + VC    
Subjt:  SCKNVKFGTMNTRAMQFI-GADAQ--NFKEWFAFIGKQAGPGLPG--SPYAMGFPSTVPVSSGMKHMNVSAYSCGDT----SLGCSCGDCPSAPVCSSTA

Query:  TPVFHRKNSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRK----SQKSPSSGTKTMPNIMDGSSLHSA-TRQKDESLPMQMLEDAPQIRSRIQL
         P         + + ++ V      +  L +   + F  W   YRK    S+ +P          +DG+   S  +  K ++     L  A         
Subjt:  TPVFHRKNSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRK----SQKSPSSGTKTMPNIMDGSSLHSA-TRQKDESLPMQMLEDAPQIRSRIQL

Query:  SVVQGYMSNFYRKYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPP------
           +  +   + ++GA+  R+P  V+  SLA ++    GL+  +V T P  LW  PGS+A +EKE+FD H  PF+R+EQ+II    +  H   P      
Subjt:  SVVQGYMSNFYRKYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPP------

Query:  ----SILNDNNIKLLFDIQKKIDGIRANYSGSSISLSDICLKPL---DQECATQSVLQYFQMNPENVDNYGG---------VEHLEYCFQHYSSA-----
              L+ + +  + D+Q  I+ I A+Y+  +++L DICL PL   ++ C   SVL YFQ +   +D+  G           H  YC +  +S      
Subjt:  ----SILNDNNIKLLFDIQKKIDGIRANYSGSSISLSDICLKPL---DQECATQSVLQYFQMNPENVDNYGG---------VEHLEYCFQHYSSA-----

Query:  --DNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVI
          D C   F  P+ P   LGGY   NY+ A+A +IT+PVNN  N +  +  RA AWE  FI   K       ++ NLT+SF +E SIE+EL RES +D+ 
Subjt:  --DNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVI

Query:  TILVASHRAIFPLIANS-----PCLPNLTADKLSCNVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHA
        TIL+ S+  +F  I+ +      C   L   K+S    LG++G+++V+ SV  S+G FS IGV  TLI++EVIPFLVLA         VGVDN+ ILV  
Subjt:  TILVASHRAIFPLIANS-----PCLPNLTADKLSCNVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHA

Query:  VKRQS--VELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLL
         +R        L+ ++   L EV PS+ L+S SE +AF +G    +PA   FS+FAG                                  +AVL+DFLL
Subjt:  VKRQS--VELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLL

Query:  QVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISCSSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIW
        Q+T FV+L+  D  R E  R+D   C++     G++ G+                                    G+ Q +   L R+ K  +AP L   
Subjt:  QVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISCSSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIW

Query:  VVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFVV-KNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPE
         ++ +VI++FVG    SIA+  ++E GL+Q + +P DSY+  YF ++S +L  GPPVYFVV + +NY+S   Q N +C    C++DSL+ +I  A+ +  
Subjt:  VVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFVV-KNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPE

Query:  SSFIAKPAASWLDDYLVWISPEAFGCCRKF-TNGSYCPPDDQPPCCTSSDGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPW
         + I    +SW+DDY  WI P++  CCR + +   +C      P C             C+  T+   +                  RP    F   LP 
Subjt:  SSFIAKPAASWLDDYLVWISPEAFGCCRKF-TNGSYCPPDDQPPCCTSSDGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPW

Query:  FLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSSRISDSLKIE-----IFPYSVFYMFFEQYLNIWRTALIN
        FLS  P+  C KGGH AY+S+V +    +GV  A+ F TYHT L    D+I++M+ A+ ++S I+ ++ +E     +FPYSVFY+F+EQYL +    + N
Subjt:  FLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSSRISDSLKIE-----IFPYSVFYMFFEQYLNIWRTALIN

Query:  LAIAIDLLRKILIPTEGMK--GVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSV
        L +++  +  + +   G +    +++   ++ I V+ +                                        GVM +  I LNA+S+VNLVMS 
Subjt:  LAIAIDLLRKILIPTEGMK--GVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSV

Query:  GIAVEFCVHLTHAFSVSS-GDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGP
        GI+VEFC H+T AF++S+ G R  R +EAL+ MG+SV SGITLTK  G++VL F+++++F ++YF+MYLA+VLLG  HGL+FLPV+LS  GP
Subjt:  GIAVEFCVHLTHAFSVSS-GDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGP

Q6T3U3 NPC1-like intracellular cholesterol transporter 1

9.6e-140

29.49

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Query:  KHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQNLNPDNLLSSKIQSLCPTI-----TGNVCCTEQQFDTLRSQ
        KH  G C  Y  C K P+        G  S+ +   +SN                   +++  ++L  + +Q +CP +     T   CC+ +Q  +L S 
Subjt:  KHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQNLNPDNLLSSKIQSLCPTI-----TGNVCCTEQQFDTLRSQ

Query:  VMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLK--VNNSLTVDAIDYYVADAFGEGLFESCKNVKFGTMNTRAMQFI----GADAQNFKEW
        +      L  CPAC  NF++L C  TCSP+QSLFINVT V++        V A + +   +F E  +ESC  V+     + A+  +    G+   N + W
Subjt:  VMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLK--VNNSLTVDAIDYYVADAFGEGLFESCKNVKFGTMNTRAMQFI----GADAQNFKEW

Query:  FAFIGKQAGPGLPGSPYAMGFPSTVP---VSSGMKHMNVSAYSC----GDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVKCVDFTLCILY
          F G   G GL  +P  + F    P   +  G++ +N     C    GD S  CSC DC  A  C     P   R +    R+       + FT     
Subjt:  FAFIGKQAGPGLPGSPYAMGFPSTVP---VSSGMKHMNVSAYSC----GDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVKCVDFTLCILY

Query:  IIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGAWVARNPTLVLISSLAIVLL
         ++ SA L          K+ + G                             ++AP++  + +LS     +  F++ +G  VA  P  VL  S  +V+ 
Subjt:  IIIASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGAWVARNPTLVLISSLAIVLL

Query:  LCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNN---------IKLLFDIQKKIDGIR--ANYSGSSI
        L  GL   ++ T P +LW  P S+A +EK F D H  PF+R  QI +     + +     +L   N         +  L ++Q+++  ++  +  +  +I
Subjt:  LCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNN---------IKLLFDIQKKIDGIR--ANYSGSSI

Query:  SLSDICLKPLD------QECATQSVLQYFQMN--------PENVDNYGGV----EHLEYC------FQHYSS-ADNCRSAFEAPLDPSTALGGYSGNNYS
        SL DIC  PL+       +C   S+LQYFQ N         + ++    +    +H  YC      F+  +S A +C + + AP+ P  A+GGY G +YS
Subjt:  SLSDICLKPLD------QECATQSVLQYFQMN--------PENVDNYGGV----EHLEYC------FQHYSS-ADNCRSAFEAPLDPSTALGGYSGNNYS

Query:  EASAFLITYPVNNAINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIANS-PCLPNLTADK
        EA A +IT+ +NN    +     +A  WE+AF  L + E      S    ++FS+E S+E+E+ R +  D + +   S+  +F  I+ +       +   
Subjt:  EASAFLITYPVNNAINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIANS-PCLPNLTADK

Query:  LSCNVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGR---ISNALVEVGPSITLAS
        +     LGL GV++V+ +VL ++GF+S +GV S+L+I++V+PFLVLA         VG DN+ I V   +R    +P E R   I   L  V PS+ L S
Subjt:  LSCNVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGR---ISNALVEVGPSITLAS

Query:  LSEVLAFAVGSFIPMPACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSG
        LSE + F +G+  PMPA R F++ +G                                  LA++LDFLLQ+TAFVAL+  D  R E  R           
Subjt:  LSEVLAFAVGSFIPMPACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSG

Query:  YAGSDKGSIFTLIISCSSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQK
                                 PD+L        C     L   +   GLL R+ ++I+AP L    ++ VV+ +F+    A++ L   I  GL+Q+
Subjt:  YAGSDKGSIFTLIISCSSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQK

Query:  IVLPKDSYLQGYFNNISEHLRIGPPVYFV-VKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFT
        + LPKDSYL  YF  ++ +L +GPPVYFV    +N+SSE+   N  CS + C S SL  +I  AS  P+ S++A  A+SW+DD++ W++P +  CCR + 
Subjt:  IVLPKDSYLQGYFNNISEHLRIGPPVYFV-VKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFT

Query:  NG----SYCPPDDQPPCCTSSDGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYE
         G     +CP  D    C              K+C                ++  L   RP+  QF + LPWFL+  P+  C KGG  AY +SV L    
Subjt:  NG----SYCPPDDQPPCCTSSDGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYE

Query:  NGVIQASSFRTYHTPLNKQVDYINSMRAAQELSSRISDSLK--------IEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVS
        +G + AS F  YH PL    D+  ++RA++ L++ I+  L+         E+FPY++  +F++QYL +    +  LA+         +PT       VV 
Subjt:  NGVIQASSFRTYHTPLNKQVDYINSMRAAQELSSRISDSLK--------IEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVS

Query:  DGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSS-GDRNQRMK
                              Y L G+D  C G   +  I   L + I  G+MA+  I  NA+S++NLV +VG++VEF  H+T +F+VS+   R +R K
Subjt:  DGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSS-GDRNQRMK

Query:  EALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQ
        +A   MG++V +G+ +T   G+L+L F++ ++  +++F++ L + LLG LHGLVFLPV+LS  GP      V+++
Subjt:  EALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQ

Q9UHC9 NPC1-like intracellular cholesterol transporter 1

1.0e-141

29.4

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Query:  HSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQNLNPDNLLSSKIQSLCPTI-TG---NVCCTEQQFDTLRSQVM
        H  GYCA Y  C K P+                     + G  +  +  + L     + +  D+L+   +Q +CP + TG     CC+ +Q  +L + + 
Subjt:  HSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQNLNPDNLLSSKIQSLCPTI-TG---NVCCTEQQFDTLRSQVM

Query:  QAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSV--LKVNNSLTVDAIDYYVADAFGEGLFESCKNVKFGTMNTRAMQFI----GADAQNFKEWFA
             L  CPAC  NF+NL C  TCSPNQSLFINVT V  L       V A + +   +F E  ++SC  V+     T A+  +    G+   N + W  
Subjt:  QAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSV--LKVNNSLTVDAIDYYVADAFGEGLFESCKNVKFGTMNTRAMQFI----GADAQNFKEWFA

Query:  FIGKQAGPGLPGSPYAMGFPSTVP---VSSGMKHMNVSAYSC----GDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVKCVDFTLCILYII
        F G   G GL  +P  + F    P   V SG++ +N     C    GD    CSC DC  A  C + A P   +    +  +G +    V      L II
Subjt:  FIGKQAGPGLPGSPYAMGFPSTVP---VSSGMKHMNVSAYSC----GDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVKCVDFTLCILYII

Query:  IASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGAWVARNPTLVLISSLAIVLLLC
        + S F   ++     + +P+     M +   G+SL         +L                       +  F++ +G WVA  P  +L+ S+  V+ L 
Subjt:  IASAFLGWSLFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGAWVARNPTLVLISSLAIVLLLC

Query:  LGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKID-----------GIRANYSGSSISL
         GL+  ++ T P +LW  P S+A  EK F D H  PF+R  Q+I+     + +     +L   N   + D+   ++            + +  +  +ISL
Subjt:  LGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKID-----------GIRANYSGSSISL

Query:  SDICLKPLD------QECATQSVLQYFQMNPE------------NVDNYGGVEHLEYC------FQHYSS-ADNCRSAFEAPLDPSTALGGYSGNNYSEA
         DIC  PL+       +C   S+LQYFQ N                      +H  YC      F+  ++ A +C + + AP+ P  A+GGY G +YSEA
Subjt:  SDICLKPLD------QECATQSVLQYFQMNPE------------NVDNYGGVEHLEYC------FQHYSS-ADNCRSAFEAPLDPSTALGGYSGNNYSEA

Query:  SAFLITYPVNNAINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIANS-PCLPNLTADKLS
         A ++T+ +NN          +A  WE+AF++  +A    M     +T  F +E S+E+E+ R +TA+ + I   S+  IF  I+ +     + +   + 
Subjt:  SAFLITYPVNNAINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIANS-PCLPNLTADKLS

Query:  CNVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKR--QSVELPLEGRISNALVEVGPSITLASLSE
            LGL GV +V+ +V+ ++GFFS +G++S+L+I++V+PFLVL+         VG DN+ I V   +R  +    P E  I  AL  V PS+ L SLSE
Subjt:  CNVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKR--QSVELPLEGRISNALVEVGPSITLASLSE

Query:  VLAFAVGSFIPMPACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAG
         + F +G+  PMPA R F++ +G                                  LAV+LDFLLQ++AFVAL+  D  R E  R+D   C+K      
Subjt:  VLAFAVGSFIPMPACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAG

Query:  SDKGSIFTLIISCSSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVL
          +G                                            GLL  + ++ +AP L  W+ + VV+ +F+     S+     I  GL+Q++ L
Subjt:  SDKGSIFTLIISCSSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVL

Query:  PKDSYLQGYFNNISEHLRIGPPVYFVVK-NYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGS
        PKDSYL  YF  ++ +  +G PVYFV    YN+SSE+   N +CS + C++ S   +I  A+  PE S++A PA+SW+DD++ W++P +  CCR + +G 
Subjt:  PKDSYLQGYFNNISEHLRIGPPVYFVVK-NYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGS

Query:  YCPPDDQPPCCTSSDGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKD---------
           P+    C ++ +  +C      K+C                +   +   RPS  QF + LPWFL+  P+  C KGG  AY++SV L           
Subjt:  YCPPDDQPPCCTSSDGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKD---------

Query:  ------YENGVIQA----------SSFRTYHTPLNKQVDYINSMRAAQELSSRISDSLK--------IEIFPYSVFYMFFEQYLNIWRTALINLAIAIDL
                +G I A          S F  YH PL    DY  ++RAA+EL++ I+  L+         E+FPY++  +F+EQYL I    L  L++    
Subjt:  ------YENGVIQA----------SSFRTYHTPLNKQVDYINSMRAAQELSSRISDSLK--------IEIFPYSVFYMFFEQYLNIWRTALINLAIAIDL

Query:  LRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVH
            L+PT  +  +L+  D  SG+      +L S +M L      VD                    + G MA+  I  NA+S++NLV +VG++VEF  H
Subjt:  LRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVH

Query:  LTHAFSVSSGDR-NQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGP
        +T +F++S+     +R KEA  +MG++V +G+ +T L G+LVL  ++ ++  +++F++ L + LLG LHGLVFLPV+LS  GP
Subjt:  LTHAFSVSSGDR-NQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGP

Arabidopsis top hits

e value

%identity

Alignment

AT1G42470.1 Patched family protein

0.0e+00

62.17

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Query:  KHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQNLNPDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAI
        K S GYCAMY IC  R DGK LNCP   PSV+                              PD+LLSSKIQSLCPTITGNVCCTE QFDTLRSQV QAI
Subjt:  KHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQNLNPDNLLSSKIQSLCPTITGNVCCTEQQFDTLRSQVMQAI

Query:  PFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGLFESCKNVKFGTMNTRAMQFIGADAQNFKEWFAFIGKQAGPG
        PF+VGCPACLRNFLNLFCELTCSP+QSLFINVTS  KV N+ TVD I YY+ D FG G++ESCKNVKFG+ N+RA+ F+GA A+NFKEWF FIG++AG  
Subjt:  PFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGLFESCKNVKFGTMNTRAMQFIGADAQNFKEWFAFIGKQAGPG

Query:  LPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQ
        LPGSPY + F  T PVSSGM+ MNVS YSCGD SLGCSCGDCPSA  CSS A     +K+SCS++IGSL+VKCVDF L ILYI++ S FLG  L +    
Subjt:  LPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWSLFYRKSQ

Query:  KSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLW
        K  +S   T+         +S  +QK +++  QML++ PQ R+  QLS VQG+++NFY KYG WVAR+PTLVL  S+++VLLLC+GLIRFKVETRPDKLW
Subjt:  KSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLW

Query:  VGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKIDGIRANYSGSSISLSDICLKPLDQECATQSVL-QYFQMNPE
        VG GS+A++EK+FFD HLAPFYRIEQ+IIATV  + H K P IL D+NIKLLFDIQKK+DG+RAN+SGS +SL+DIC+KPL ++CATQSVL QYF+M PE
Subjt:  VGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKIDGIRANYSGSSISLSDICLKPLDQECATQSVL-QYFQMNPE

Query:  NVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSF
        N D+YGGV+H++YCF+H++S ++C SAF+ PLDP+TALGG+SGN++SEASAFL+TYPV+N ++ +GN++ +AVAWEKAFIQLAK ELL MVQ++NLTLSF
Subjt:  NVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSF

Query:  SSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFI
        SSESSIEEELKRESTADVITI + S+  +F  I+      P L +  ++  VLLGLSGV+LVMLSVLGSVGFFSA+G+KSTLIIMEVIPFLVLA      
Subjt:  SSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFI

Query:  RFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSF
           VGVDNMCILVHAVKRQ  ELPLE RISNAL+EVGPSITLASL+E+LAFAVG+FI MPA RVFSMFA                               
Subjt:  RFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSF

Query:  SYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISCSSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLAR
           ALAVLLDFLLQ+TAFVALIVFDF RTEDKRVDCFPCIK+S      K SI                                   G+ QR  GLL R
Subjt:  SYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGYAGSDKGSIFTLIISCSSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLAR

Query:  YMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSL
        YMKE+HAP LS W+VKIVVI+ F G  +A IAL TRIE GLEQ+IVLP+DSYLQGYFNNIS +LRIGPP+YFV+KNYNYSSESR TNQLCSI++C+ +SL
Subjt:  YMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSL

Query:  LNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSSDGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRP
        LNEIA+ASL PE S+IAKPAASWLDD+LVW+SPEAFGCCRKFTNG++CPPDDQPPCC      SCGL+ +CKDCTT            CF H+DL   RP
Subjt:  LNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSSDGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRP

Query:  STAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIW
        ST QFKEKLPWFL+ALPSADCAKGGHGAY+SSV+L+ Y NG+IQASSFRTYHTPLNKQVD++NSMRAAQE S+++S SLK+EI+PYSVFYMFFEQYL+IW
Subjt:  STAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIW

Query:  RTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNL
        +TALINL+IAI  +  + +       ++  S   S I +   + +  +L+                                GVMA+ +IQLNA+SVVNL
Subjt:  RTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNL

Query:  VMSVGIAVEFCVHLTHAFS
        +MSVGIAVEFCVH+THAFS
Subjt:  VMSVGIAVEFCVHLTHAFS

AT4G38350.1 Patched family protein

0.0e+00

59.53

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Query:  LLQVLCFILSYAERSNTSTNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQNLNPDNLLSSKIQSLC
        LL +  F  S    +N + +  S  +HS+ YCAMY IC  R DGK LNCP  +PS+Q                              PD L S+KIQSLC
Subjt:  LLQVLCFILSYAERSNTSTNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQNLNPDNLLSSKIQSLC

Query:  PTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGLFESCKNVKFGTMNTRA
        PTI+GNVCCTE QFDTLRSQV QA+PFLVGCPACLRNFLNLFCEL+CSPNQSLFINVTSV +V+ +LTVD IDY++ D FGEGL+ESCK VKFGTMNTRA
Subjt:  PTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGLFESCKNVKFGTMNTRA

Query:  MQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVKCVD
        + F+G  A+NF+EWF FIG++A  G PGSPYA+ F S++P SS M  MNVS YSCGDTSLGCSCGDCPS+P CSS      H ++SCS+RIG LKV+C++
Subjt:  MQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVKCVD

Query:  FTLCILYIIIASAFLGWS-LFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGAWVARNPTLVLI
         ++ ++Y+++ S F GW+ L  R++   P   +K + + ++   ++S    K+  L +       +++   QLS VQ YM+ FYR YG+W+ARNP+LVL 
Subjt:  FTLCILYIIIASAFLGWS-LFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGAWVARNPTLVLI

Query:  SSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKIDGIRANYSGSSISLS
         S+AIVL LC GL  FKVETRP+KLWVGP SKA++EK+FFD HL+PFYRIEQ+I+ATVPD   G+ PSI+ D NI LLFDIQ+K+D IR NYSGS +SL 
Subjt:  SSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKIDGIRANYSGSSISLS

Query:  DICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAVAW
        DICLKPL ++CATQS+LQYF+M+    D+YGGVEH EYCFQHY+S++ C SAF+AP+DPS  LGG+SGNNYSEA+AF++TYPVNN I    NE+ RAVAW
Subjt:  DICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAVAW

Query:  EKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVVLVMLSVLGSVGFFSA
        EK+FIQLAK ELL MV+S+NL+LSFSSESSIEEELKRESTADVITI  AS+  +F  I+      P      +S  VLLGLSGVVLV+LSVLGSVG FSA
Subjt:  EKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCNVLLGLSGVVLVMLSVLGSVGFFSA

Query:  IGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAGLTICP
        +GVKSTLIIMEVIPFLVLA         VGVDNMCILVHAVKRQ  E+ LE RIS+ALVEVGPSITLASLSEVLAFAVG+F+PMPACR+FSMFA      
Subjt:  IGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAGLTICP

Query:  LQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIK--SSGYAGSDKGSIFTLIISCSSFLFKYACPDLL
                                    ALA++LDF LQ+TAFVALIVFD  R+ D R+DCFPCIK  SS     + G                      
Subjt:  LQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIK--SSGYAGSDKGSIFTLIISCSSFLFKYACPDLL

Query:  VHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFV
                           R PG L RYMKE+HAP L +W VK+VV+++F  F LASIA+  R+E GLEQKIVLP+DSYLQ YF+++SE+LR+GPP+YFV
Subjt:  VHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQGYFNNISEHLRIGPPVYFV

Query:  VKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSSDGGSCGLNGICKD
        VKNYNYSSESR TNQLCSISQC+S+SLLNEI++AS   ++S+IAKPAASWLDD+LVW+SPEAFGCCRKFTNGSYCPPDDQPPCCT+ +   C L+GICKD
Subjt:  VKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSSDGGSCGLNGICKD

Query:  CTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSS
        CTT            CF HSDL   RPSTAQF+EKLPWFL+ALPSADCAKGGHGAYT+SV+LK YE+GVIQAS FRTYHTPLN Q DY+N++RAA+E SS
Subjt:  CTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSS

Query:  RISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKI--LIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFF
        RIS+SLKI+IFPYSVFY+FFEQYLNIW  AL NLAIAI  +  +  LI +      ++V              L   L+DL                   
Subjt:  RISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKI--LIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFF

Query:  IPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMY
                   G+M IL IQLNA+SVVNL+MS+GIAVEFCVH++HAF +SSGDR  R +EAL TMGASV SGITLTKLVGV+VLCF+R+E+FVVYYFQMY
Subjt:  IPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMY

Query:  LALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTSLL
        LALV++GFLHGLVFLPV+LSL GPP   + +EQQ    ++S L
Subjt:  LALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTSLL

AT4G38350.2 Patched family protein

0.0e+00

58.55

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Query:  LLQVLCFILSYAERSNTSTNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQNLNPDNLLSSKIQSLC
        LL +  F  S    +N + +  S  +HS+ YCAMY IC  R DGK LNCP  +PS+Q                              PD L S+KIQSLC
Subjt:  LLQVLCFILSYAERSNTSTNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQNLNPDNLLSSKIQSLC

Query:  PTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGLFESCKNVKFGTMNTRA
        PTI+GNVCCTE QFDTLRSQV QA+PFLVGCPACLRNFLNLFCEL+CSPNQSLFINVTSV +V+ +LTVD IDY++ D FGEGL+ESCK VKFGTMNTRA
Subjt:  PTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGLFESCKNVKFGTMNTRA

Query:  MQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVKCVD
        + F+G  A+NF+EWF FIG++A  G PGSPYA+ F S++P SS M  MNVS YSCGDTSLGCSCGDCPS+P CSS      H ++SCS+RIG LKV+C++
Subjt:  MQFIGADAQNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVKCVD

Query:  FTLCILYIIIASAFLGWS-LFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGAWVARNPTLVLI
         ++ ++Y+++ S F GW+ L  R++   P   +K + + ++   ++S    K+  L +       +++   QLS VQ YM+ FYR YG+W+ARNP+LVL 
Subjt:  FTLCILYIIIASAFLGWS-LFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGAWVARNPTLVLI

Query:  SSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKIDGIRANYSGSSISLS
         S+AIVL LC GL  FKVETRP+KLWVGP SKA++EK+FFD HL+PFYRIEQ+I+ATVPD   G+ PSI+ D NI LLFDIQ+K+D IR NYSGS +SL 
Subjt:  SSLAIVLLLCLGLIRFKVETRPDKLWVGPGSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKIDGIRANYSGSSISLS

Query:  DICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSE------------------------ASA
        DICLKPL ++CATQS+LQYF+M+    D+YGGVEH EYCFQHY+S++ C SAF+AP+DPS  LGG+SGNNYSE                        A+A
Subjt:  DICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYCFQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSE------------------------ASA

Query:  FLITYPVNNAINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCN
        F++TYPVNN I    NE+ RAVAWEK+FIQLAK ELL MV+S+NL+LSFSSESSIEEELKRESTADVITI  AS+  +F  I+      P      +S  
Subjt:  FLITYPVNNAINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVASHRAIFPLIA-NSPCLPNLTADKLSCN

Query:  VLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAF
        VLLGLSGVVLV+LSVLGSVG FSA+GVKSTLIIMEVIPFLVLA         VGVDNMCILVHAVKRQ  E+ LE RIS+ALVEVGPSITLASLSEVLAF
Subjt:  VLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVEVGPSITLASLSEVLAF

Query:  AVGSFIPMPACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIK--SSGYAGSD
        AVG+F+PMPACR+FSMFA                                  ALA++LDF LQ+TAFVALIVFD  R+ D R+DCFPCIK  SS     +
Subjt:  AVGSFIPMPACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIK--SSGYAGSD

Query:  KGSIFTLIISCSSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPK
         G                                         R PG L RYMKE+HAP L +W VK+VV+++F  F LASIA+  R+E GLEQKIVLP+
Subjt:  KGSIFTLIISCSSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPK

Query:  DSYLQGYFNNISEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCP
        DSYLQ YF+++SE+LR+GPP+YFVVKNYNYSSESR TNQLCSISQC+S+SLLNEI++AS   ++S+IAKPAASWLDD+LVW+SPEAFGCCRKFTNGSYCP
Subjt:  DSYLQGYFNNISEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCP

Query:  PDDQPPCCTSSDGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFR
        PDDQPPCCT+ +   C L+GICKDCTT            CF HSDL   RPSTAQF+EKLPWFL+ALPSADCAKGGHGAYT+SV+LK YE+GVIQAS FR
Subjt:  PDDQPPCCTSSDGGSCGLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFR

Query:  TYHTPLNKQVDYINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKI--LIPTEGMKGVLVVSDGVSGIEVDRYSSLTS
        TYHTPLN Q DY+N++RAA+E SSRIS+SLKI+IFPYSVFY+FFEQYLNIW  AL NLAIAI  +  +  LI +      ++V              L  
Subjt:  TYHTPLNKQVDYINSMRAAQELSSRISDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKI--LIPTEGMKGVLVVSDGVSGIEVDRYSSLTS

Query:  NLMDLGYHLAGVDNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLT
         L+DL                              G+M IL IQLNA+SVVNL+MS+GIAVEFCVH++HAF +SSGDR  R +EAL TMGASV SGITLT
Subjt:  NLMDLGYHLAGVDNDCCGSHGIFFIPNYLWNAISEGVMAILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLT

Query:  KLVGVLVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTSLL
        KLVGV+VLCF+R+E+FVVYYFQMYLALV++GFLHGLVFLPV+LSL GPP   + +EQQ    ++S L
Subjt:  KLVGVLVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGPPSRCVFVEQQDNRPSTSLL

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGAGGCTCCGTCTAGGGTTTATCGCGTTAATTTATCTCCTCCAGGTTCTATGTTTTATCCTGTCGTATGCAGAGAGGTCTAATACATCTACGAATGGCATATCCGGGGA
AAAACACTCTGAAGGATATTGCGCAATGTATGGTATCTGTGCAAAACGACCCGATGGTAAAGCGCTGAACTGTCCTACTGGTGCCCCATCTGTGCAGCACTATCCATATG
TTAGTAATGTTGGCGGTTTTAAAGTAAAATATGCAGGATCAGCTGGTCTGCCTTTCTGTTTCCATCAAAATCTTAATCCAGATAATCTTCTATCGTCAAAGATCCAAAGT
CTATGTCCAACTATTACTGGCAATGTTTGTTGCACAGAACAACAATTCGACACCCTACGATCACAAGTAATGCAAGCTATTCCATTTCTTGTAGGTTGTCCAGCATGCTT
AAGAAACTTTTTGAACCTGTTCTGTGAGCTTACCTGTTCTCCAAATCAGAGCTTATTCATCAATGTAACTTCTGTTTTAAAGGTTAATAACAGCCTTACGGTTGATGCCA
TTGATTATTATGTAGCTGATGCTTTTGGTGAAGGGCTATTTGAGTCCTGCAAAAATGTAAAATTTGGTACGATGAACACTCGAGCCATGCAATTTATCGGTGCTGATGCT
CAAAATTTTAAAGAGTGGTTTGCTTTTATTGGTAAACAAGCTGGCCCTGGCTTGCCTGGTTCACCATATGCCATGGGATTTCCATCTACCGTGCCTGTGTCATCTGGAAT
GAAGCATATGAATGTATCTGCTTATTCTTGTGGAGATACTTCACTGGGATGTTCCTGTGGTGATTGCCCTTCAGCACCAGTCTGTAGTAGTACTGCAACCCCTGTTTTCC
ATAGAAAAAATTCTTGTTCAGTGAGAATTGGGTCTCTCAAGGTCAAATGTGTTGACTTCACTCTGTGTATCCTGTACATTATAATTGCCTCTGCTTTTCTTGGGTGGAGT
TTGTTTTATCGCAAATCCCAAAAGAGCCCTTCTTCGGGAACTAAAACAATGCCAAATATCATGGATGGGAGCAGTCTCCATTCTGCTACTAGGCAAAAGGATGAAAGTTT
GCCGATGCAGATGCTTGAAGATGCTCCTCAAATCAGAAGTAGGATTCAGCTTTCAGTTGTTCAGGGATACATGTCCAATTTTTACAGGAAATATGGAGCATGGGTGGCAA
GAAATCCAACATTGGTGTTGATTTCATCACTCGCCATTGTTCTGCTTCTGTGTTTAGGTCTCATTCGTTTCAAGGTGGAGACAAGGCCTGATAAGCTATGGGTAGGACCA
GGAAGCAAAGCATCCCAAGAGAAGGAATTTTTTGATGCACATCTAGCCCCTTTTTACAGGATTGAACAGATTATAATAGCCACAGTTCCAGATACCATGCATGGAAAGCC
GCCAAGTATTCTGAATGATAACAATATTAAGTTATTGTTTGACATACAAAAGAAGATAGATGGTATTCGAGCTAATTATTCTGGTTCAAGTATATCTCTAAGTGACATTT
GCTTGAAGCCACTGGATCAGGAATGTGCCACTCAGAGTGTCCTGCAGTATTTCCAGATGAATCCAGAAAATGTTGATAACTATGGAGGAGTCGAACATCTTGAATATTGT
TTTCAGCACTATTCCTCTGCAGACAATTGCAGGAGTGCATTTGAAGCTCCTCTTGATCCAAGCACCGCATTAGGGGGATACTCTGGGAACAACTATTCAGAAGCCTCTGC
TTTCTTAATAACATATCCAGTGAACAATGCTATTAACAAGGAAGGGAATGAATCTGGTCGAGCTGTGGCTTGGGAGAAAGCCTTTATTCAGTTGGCTAAGGCTGAGTTAT
TGACAATGGTGCAATCTCAAAATTTGACGCTTTCTTTTTCTTCGGAAAGCTCCATCGAAGAAGAATTAAAAAGAGAGAGCACTGCTGATGTCATCACAATCTTGGTGGCT
TCCCATCGTGCCATTTTCCCTCTAATTGCCAATTCACCCTGTTTACCTAATTTAACTGCAGATAAGCTATCTTGTAATGTGTTACTTGGTCTCTCTGGAGTTGTACTTGT
CATGTTGTCTGTTCTTGGATCAGTAGGTTTTTTCAGTGCTATTGGAGTTAAATCTACTCTAATCATTATGGAAGTTATTCCTTTCCTTGTTCTGGCAGTAAGTTCTGCCT
TCATCCGCTTCATTGTTGGGGTGGATAATATGTGTATATTGGTACATGCTGTTAAACGGCAGTCAGTAGAATTGCCTTTGGAAGGACGAATTAGCAATGCACTTGTAGAA
GTTGGACCATCCATCACACTAGCAAGTTTATCTGAGGTTCTTGCATTTGCAGTTGGAAGTTTCATTCCTATGCCAGCATGTCGTGTTTTTTCCATGTTTGCAGGTTTGAC
TATTTGTCCATTGCAAAGCTCTCAAGGATGCTTGAGATATATTTTAACTGAGACAGGCATAGATTTCCAATCACCATTTTCATTTTCTTATACAGCATTGGCCGTTCTTC
TGGACTTCCTGCTGCAAGTTACAGCTTTTGTTGCTCTCATAGTGTTTGATTTTTTAAGAACAGAGGATAAGAGAGTTGACTGTTTTCCATGTATTAAGAGCTCAGGATAT
GCTGGCAGTGATAAAGGTAGTATCTTCACACTTATTATATCTTGCTCTTCTTTTCTTTTTAAATATGCTTGTCCAGATTTATTGGTGCACTTCATCGGGATGATGCCTTG
TCTTGTTGAATATTATTTAGGCATCACTCAGAGGAATCCTGGCTTGTTAGCCCGATACATGAAGGAGATCCATGCACCAGCACTTAGCATCTGGGTAGTCAAAATAGTTG
TCATATCCATCTTTGTTGGGTTCACATTGGCAAGCATTGCACTATGCACAAGAATTGAAGCTGGTTTGGAACAAAAGATTGTCCTACCCAAAGATTCTTATCTTCAGGGG
TACTTCAATAACATTTCAGAACATCTCAGAATAGGTCCACCAGTATATTTCGTTGTAAAGAACTACAATTACAGCTCAGAATCAAGACAGACAAACCAATTATGCTCCAT
CAGTCAATGTGACTCAGACTCTCTTTTAAATGAGATTGCAAAAGCTTCACTAATTCCAGAGTCAAGTTTCATTGCTAAACCAGCTGCTTCATGGCTTGATGATTATCTTG
TGTGGATATCTCCAGAAGCATTTGGCTGCTGTCGGAAGTTCACAAATGGAAGCTATTGCCCCCCTGATGATCAGCCCCCTTGCTGTACTTCAAGTGATGGTGGTTCTTGT
GGTCTGAACGGAATATGCAAAGATTGTACAACGTATTTTGCTAAATTGGCAGCCAGTCCTGAGTCATGGTGTTTTCTTCACTCGGATCTGCATGGTGGTAGGCCATCTAC
TGCACAATTTAAGGAGAAATTGCCATGGTTCCTCAGTGCTCTACCTTCTGCTGACTGTGCTAAAGGAGGTCATGGGGCATATACTAGTAGTGTTGAACTGAAAGACTATG
AAAATGGTGTTATTCAAGCATCTTCCTTCAGAACGTACCATACACCCCTGAATAAGCAGGTTGACTATATTAATTCGATGAGGGCTGCTCAAGAATTGAGTTCAAGAATT
TCTGATTCTTTGAAGATAGAGATCTTTCCGTATTCTGTATTTTACATGTTTTTTGAGCAATACCTCAATATATGGAGAACAGCATTGATCAACCTTGCCATCGCTATTGA
CCTTCTAAGGAAAATTCTCATCCCAACTGAAGGTATGAAAGGTGTCTTGGTGGTTAGTGATGGTGTTTCTGGCATTGAAGTAGACAGATATTCTTCTCTTACGTCAAATC
TTATGGACCTCGGCTATCATCTTGCTGGTGTTGACAATGATTGTTGTGGATCTCATGGTATTTTCTTCATTCCTAATTATCTCTGGAACGCTATATCAGAAGGCGTGATG
GCAATTTTGAATATCCAATTGAACGCAATCTCTGTCGTCAATCTTGTCATGTCTGTGGGAATTGCTGTTGAATTTTGTGTGCATTTGACACATGCTTTCTCGGTAAGCAG
TGGAGATAGAAACCAACGGATGAAGGAGGCTCTTAGTACAATGGGAGCATCTGTTCTTAGTGGAATCACACTAACAAAGCTAGTTGGGGTCCTTGTACTTTGCTTCTCTA
GGACTGAAGTTTTTGTGGTTTATTATTTCCAAATGTACTTGGCATTAGTACTTCTTGGATTTTTGCACGGCCTCGTATTCTTGCCGGTAATGTTGAGCTTGTTTGGTCCA
CCTTCAAGATGTGTATTCGTCGAGCAACAAGACAATCGGCCCTCTACTTCGCTTTTGAAGGTCTGGCGCATTCATTGGCATACATGCTTAAACGCCAATAAAGAAAGGAA
GAGAAAATATATAAAAATGACATTTAAGTTGATGGTATCAGACAATTCTGATATCGTTGATTATCATGTTAGTGAATATTGTTGTGATTTTGGCAAATCCAAAGTAGATG
TGCAGAATTTTGCGTCCTGA

mRNA sequence

Show/hide mRNA sequence

TTTTTCTCTCCCGCTTTCCTCTCCTGGCGGTTTTGCTCTTCTTGGTACAGGACCCATCTTCTACTCATCTACTCCACAATGAGGCTCCGTCTAGGGTTTATCGCGTTAAT
TTATCTCCTCCAGGTTCTATGTTTTATCCTGTCGTATGCAGAGAGGTCTAATACATCTACGAATGGCATATCCGGGGAAAAACACTCTGAAGGATATTGCGCAATGTATG
GTATCTGTGCAAAACGACCCGATGGTAAAGCGCTGAACTGTCCTACTGGTGCCCCATCTGTGCAGCACTATCCATATGTTAGTAATGTTGGCGGTTTTAAAGTAAAATAT
GCAGGATCAGCTGGTCTGCCTTTCTGTTTCCATCAAAATCTTAATCCAGATAATCTTCTATCGTCAAAGATCCAAAGTCTATGTCCAACTATTACTGGCAATGTTTGTTG
CACAGAACAACAATTCGACACCCTACGATCACAAGTAATGCAAGCTATTCCATTTCTTGTAGGTTGTCCAGCATGCTTAAGAAACTTTTTGAACCTGTTCTGTGAGCTTA
CCTGTTCTCCAAATCAGAGCTTATTCATCAATGTAACTTCTGTTTTAAAGGTTAATAACAGCCTTACGGTTGATGCCATTGATTATTATGTAGCTGATGCTTTTGGTGAA
GGGCTATTTGAGTCCTGCAAAAATGTAAAATTTGGTACGATGAACACTCGAGCCATGCAATTTATCGGTGCTGATGCTCAAAATTTTAAAGAGTGGTTTGCTTTTATTGG
TAAACAAGCTGGCCCTGGCTTGCCTGGTTCACCATATGCCATGGGATTTCCATCTACCGTGCCTGTGTCATCTGGAATGAAGCATATGAATGTATCTGCTTATTCTTGTG
GAGATACTTCACTGGGATGTTCCTGTGGTGATTGCCCTTCAGCACCAGTCTGTAGTAGTACTGCAACCCCTGTTTTCCATAGAAAAAATTCTTGTTCAGTGAGAATTGGG
TCTCTCAAGGTCAAATGTGTTGACTTCACTCTGTGTATCCTGTACATTATAATTGCCTCTGCTTTTCTTGGGTGGAGTTTGTTTTATCGCAAATCCCAAAAGAGCCCTTC
TTCGGGAACTAAAACAATGCCAAATATCATGGATGGGAGCAGTCTCCATTCTGCTACTAGGCAAAAGGATGAAAGTTTGCCGATGCAGATGCTTGAAGATGCTCCTCAAA
TCAGAAGTAGGATTCAGCTTTCAGTTGTTCAGGGATACATGTCCAATTTTTACAGGAAATATGGAGCATGGGTGGCAAGAAATCCAACATTGGTGTTGATTTCATCACTC
GCCATTGTTCTGCTTCTGTGTTTAGGTCTCATTCGTTTCAAGGTGGAGACAAGGCCTGATAAGCTATGGGTAGGACCAGGAAGCAAAGCATCCCAAGAGAAGGAATTTTT
TGATGCACATCTAGCCCCTTTTTACAGGATTGAACAGATTATAATAGCCACAGTTCCAGATACCATGCATGGAAAGCCGCCAAGTATTCTGAATGATAACAATATTAAGT
TATTGTTTGACATACAAAAGAAGATAGATGGTATTCGAGCTAATTATTCTGGTTCAAGTATATCTCTAAGTGACATTTGCTTGAAGCCACTGGATCAGGAATGTGCCACT
CAGAGTGTCCTGCAGTATTTCCAGATGAATCCAGAAAATGTTGATAACTATGGAGGAGTCGAACATCTTGAATATTGTTTTCAGCACTATTCCTCTGCAGACAATTGCAG
GAGTGCATTTGAAGCTCCTCTTGATCCAAGCACCGCATTAGGGGGATACTCTGGGAACAACTATTCAGAAGCCTCTGCTTTCTTAATAACATATCCAGTGAACAATGCTA
TTAACAAGGAAGGGAATGAATCTGGTCGAGCTGTGGCTTGGGAGAAAGCCTTTATTCAGTTGGCTAAGGCTGAGTTATTGACAATGGTGCAATCTCAAAATTTGACGCTT
TCTTTTTCTTCGGAAAGCTCCATCGAAGAAGAATTAAAAAGAGAGAGCACTGCTGATGTCATCACAATCTTGGTGGCTTCCCATCGTGCCATTTTCCCTCTAATTGCCAA
TTCACCCTGTTTACCTAATTTAACTGCAGATAAGCTATCTTGTAATGTGTTACTTGGTCTCTCTGGAGTTGTACTTGTCATGTTGTCTGTTCTTGGATCAGTAGGTTTTT
TCAGTGCTATTGGAGTTAAATCTACTCTAATCATTATGGAAGTTATTCCTTTCCTTGTTCTGGCAGTAAGTTCTGCCTTCATCCGCTTCATTGTTGGGGTGGATAATATG
TGTATATTGGTACATGCTGTTAAACGGCAGTCAGTAGAATTGCCTTTGGAAGGACGAATTAGCAATGCACTTGTAGAAGTTGGACCATCCATCACACTAGCAAGTTTATC
TGAGGTTCTTGCATTTGCAGTTGGAAGTTTCATTCCTATGCCAGCATGTCGTGTTTTTTCCATGTTTGCAGGTTTGACTATTTGTCCATTGCAAAGCTCTCAAGGATGCT
TGAGATATATTTTAACTGAGACAGGCATAGATTTCCAATCACCATTTTCATTTTCTTATACAGCATTGGCCGTTCTTCTGGACTTCCTGCTGCAAGTTACAGCTTTTGTT
GCTCTCATAGTGTTTGATTTTTTAAGAACAGAGGATAAGAGAGTTGACTGTTTTCCATGTATTAAGAGCTCAGGATATGCTGGCAGTGATAAAGGTAGTATCTTCACACT
TATTATATCTTGCTCTTCTTTTCTTTTTAAATATGCTTGTCCAGATTTATTGGTGCACTTCATCGGGATGATGCCTTGTCTTGTTGAATATTATTTAGGCATCACTCAGA
GGAATCCTGGCTTGTTAGCCCGATACATGAAGGAGATCCATGCACCAGCACTTAGCATCTGGGTAGTCAAAATAGTTGTCATATCCATCTTTGTTGGGTTCACATTGGCA
AGCATTGCACTATGCACAAGAATTGAAGCTGGTTTGGAACAAAAGATTGTCCTACCCAAAGATTCTTATCTTCAGGGGTACTTCAATAACATTTCAGAACATCTCAGAAT
AGGTCCACCAGTATATTTCGTTGTAAAGAACTACAATTACAGCTCAGAATCAAGACAGACAAACCAATTATGCTCCATCAGTCAATGTGACTCAGACTCTCTTTTAAATG
AGATTGCAAAAGCTTCACTAATTCCAGAGTCAAGTTTCATTGCTAAACCAGCTGCTTCATGGCTTGATGATTATCTTGTGTGGATATCTCCAGAAGCATTTGGCTGCTGT
CGGAAGTTCACAAATGGAAGCTATTGCCCCCCTGATGATCAGCCCCCTTGCTGTACTTCAAGTGATGGTGGTTCTTGTGGTCTGAACGGAATATGCAAAGATTGTACAAC
GTATTTTGCTAAATTGGCAGCCAGTCCTGAGTCATGGTGTTTTCTTCACTCGGATCTGCATGGTGGTAGGCCATCTACTGCACAATTTAAGGAGAAATTGCCATGGTTCC
TCAGTGCTCTACCTTCTGCTGACTGTGCTAAAGGAGGTCATGGGGCATATACTAGTAGTGTTGAACTGAAAGACTATGAAAATGGTGTTATTCAAGCATCTTCCTTCAGA
ACGTACCATACACCCCTGAATAAGCAGGTTGACTATATTAATTCGATGAGGGCTGCTCAAGAATTGAGTTCAAGAATTTCTGATTCTTTGAAGATAGAGATCTTTCCGTA
TTCTGTATTTTACATGTTTTTTGAGCAATACCTCAATATATGGAGAACAGCATTGATCAACCTTGCCATCGCTATTGACCTTCTAAGGAAAATTCTCATCCCAACTGAAG
GTATGAAAGGTGTCTTGGTGGTTAGTGATGGTGTTTCTGGCATTGAAGTAGACAGATATTCTTCTCTTACGTCAAATCTTATGGACCTCGGCTATCATCTTGCTGGTGTT
GACAATGATTGTTGTGGATCTCATGGTATTTTCTTCATTCCTAATTATCTCTGGAACGCTATATCAGAAGGCGTGATGGCAATTTTGAATATCCAATTGAACGCAATCTC
TGTCGTCAATCTTGTCATGTCTGTGGGAATTGCTGTTGAATTTTGTGTGCATTTGACACATGCTTTCTCGGTAAGCAGTGGAGATAGAAACCAACGGATGAAGGAGGCTC
TTAGTACAATGGGAGCATCTGTTCTTAGTGGAATCACACTAACAAAGCTAGTTGGGGTCCTTGTACTTTGCTTCTCTAGGACTGAAGTTTTTGTGGTTTATTATTTCCAA
ATGTACTTGGCATTAGTACTTCTTGGATTTTTGCACGGCCTCGTATTCTTGCCGGTAATGTTGAGCTTGTTTGGTCCACCTTCAAGATGTGTATTCGTCGAGCAACAAGA
CAATCGGCCCTCTACTTCGCTTTTGAAGGTCTGGCGCATTCATTGGCATACATGCTTAAACGCCAATAAAGAAAGGAAGAGAAAATATATAAAAATGACATTTAAGTTGA
TGGTATCAGACAATTCTGATATCGTTGATTATCATGTTAGTGAATATTGTTGTGATTTTGGCAAATCCAAAGTAGATGTGCAGAATTTTGCGTCCTGA

Protein sequence

Show/hide protein sequence

MRLRLGFIALIYLLQVLCFILSYAERSNTSTNGISGEKHSEGYCAMYGICAKRPDGKALNCPTGAPSVQHYPYVSNVGGFKVKYAGSAGLPFCFHQNLNPDNLLSSKIQS
LCPTITGNVCCTEQQFDTLRSQVMQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVLKVNNSLTVDAIDYYVADAFGEGLFESCKNVKFGTMNTRAMQFIGADA
QNFKEWFAFIGKQAGPGLPGSPYAMGFPSTVPVSSGMKHMNVSAYSCGDTSLGCSCGDCPSAPVCSSTATPVFHRKNSCSVRIGSLKVKCVDFTLCILYIIIASAFLGWS
LFYRKSQKSPSSGTKTMPNIMDGSSLHSATRQKDESLPMQMLEDAPQIRSRIQLSVVQGYMSNFYRKYGAWVARNPTLVLISSLAIVLLLCLGLIRFKVETRPDKLWVGP
GSKASQEKEFFDAHLAPFYRIEQIIIATVPDTMHGKPPSILNDNNIKLLFDIQKKIDGIRANYSGSSISLSDICLKPLDQECATQSVLQYFQMNPENVDNYGGVEHLEYC
FQHYSSADNCRSAFEAPLDPSTALGGYSGNNYSEASAFLITYPVNNAINKEGNESGRAVAWEKAFIQLAKAELLTMVQSQNLTLSFSSESSIEEELKRESTADVITILVA
SHRAIFPLIANSPCLPNLTADKLSCNVLLGLSGVVLVMLSVLGSVGFFSAIGVKSTLIIMEVIPFLVLAVSSAFIRFIVGVDNMCILVHAVKRQSVELPLEGRISNALVE
VGPSITLASLSEVLAFAVGSFIPMPACRVFSMFAGLTICPLQSSQGCLRYILTETGIDFQSPFSFSYTALAVLLDFLLQVTAFVALIVFDFLRTEDKRVDCFPCIKSSGY
AGSDKGSIFTLIISCSSFLFKYACPDLLVHFIGMMPCLVEYYLGITQRNPGLLARYMKEIHAPALSIWVVKIVVISIFVGFTLASIALCTRIEAGLEQKIVLPKDSYLQG
YFNNISEHLRIGPPVYFVVKNYNYSSESRQTNQLCSISQCDSDSLLNEIAKASLIPESSFIAKPAASWLDDYLVWISPEAFGCCRKFTNGSYCPPDDQPPCCTSSDGGSC
GLNGICKDCTTYFAKLAASPESWCFLHSDLHGGRPSTAQFKEKLPWFLSALPSADCAKGGHGAYTSSVELKDYENGVIQASSFRTYHTPLNKQVDYINSMRAAQELSSRI
SDSLKIEIFPYSVFYMFFEQYLNIWRTALINLAIAIDLLRKILIPTEGMKGVLVVSDGVSGIEVDRYSSLTSNLMDLGYHLAGVDNDCCGSHGIFFIPNYLWNAISEGVM
AILNIQLNAISVVNLVMSVGIAVEFCVHLTHAFSVSSGDRNQRMKEALSTMGASVLSGITLTKLVGVLVLCFSRTEVFVVYYFQMYLALVLLGFLHGLVFLPVMLSLFGP
PSRCVFVEQQDNRPSTSLLKVWRIHWHTCLNANKERKRKYIKMTFKLMVSDNSDIVDYHVSEYCCDFGKSKVDVQNFAS

Clc11G20110 (gene) of Watermelon (cordophanus) v2 genome