CuGenDBv2

Gene ID	CmUC10G193640
Organism	Citrullus mucosospermus (Watermelon (USVL531) v1)
Description	DNA topoisomerase 2
Genome location	CmU531Chr10:24784872..24791764
RNA-Seq Expression	CmUC10G193640
Synteny	CmUC10G193640
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0043231 - intracellular membrane-bounded organelle (cellular component) GO:0003677 - DNA binding (molecular function) GO:0046872 - metal ion binding (molecular function) GO:0005524 - ATP binding (molecular function) GO:0003918 - DNA topoisomerase type II (ATP-hydrolyzing) activity (molecular function)
InterPro domains	IPR013506 - DNA topoisomerase, type IIA, subunit B, domain 2 IPR036890 - Histidine kinase/HSP90-like ATPase superfamily IPR034157 - DNA topoisomerase 2, TOPRIM domain IPR031660 - C-terminal associated domain of TOPRIM IPR020568 - Ribosomal protein S5 domain 2-type fold IPR018522 - DNA topoisomerase, type IIA, conserved site IPR014721 - Ribosomal protein S5 domain 2-type fold, subgroup IPR013760 - DNA topoisomerase, type IIA-like domain superfamily IPR013759 - DNA topoisomerase, type IIA, subunit B, C-terminal IPR013758 - DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta IPR013757 - Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily IPR006171 - TOPRIM domain IPR003594 - Histidine kinase/HSP90-like ATPase IPR002205 - DNA topoisomerase, type IIA, subunit A/C-terminal IPR001241 - DNA topoisomerase, type IIA IPR001154 - DNA topoisomerase II, eukaryotic-type

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0048368.1 DNA topoisomerase 2 [Cucumis melo var. makuwa]

0.0e+00

91.16

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Query:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSN  NVDS PAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VFNDNMGKKSEPIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P+KSFQDYVDLYLKSAS+FQ EPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVK+YLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNPSFDSQTKETLTKR NSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATH+NGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLT+HKKDFIWQDDNDGEAIELAFSKKKIEDRKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRMLDGE MLPMDPWYRGFSGTIEKT+TK+GGT+YT+SGIIEEVSDTTLRI+ELPVRRWT+DYKDFLDSVTRVA+KH  DKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKR LL+NLEMELLKLENKVRFILAVVN EI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
         VSNR++VDLFHELQAKGFTPFPKKTKSVEPE+AGASNETDEAEESPE VKGER+SDYEYLLAL IGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA
        LNDLD+LEKELDE+DRNDAQ ME+RKQQR+K+NNDLKPKISRNAPKAPRNSKKT N ETVTESMDTT SS+TTEVANNPVVKPKGKAAPRKAPA KKGKA
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA

Query:  AVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS--EDDDDLEIKEVAPPAAKKGGGRGGGRKA
        AV D++D+DE+LELKDRLAAYKIESSPEPSEVSAMETEV +VQAAKKKEPSKRA  KKKTTAKSAQISIS  EDDDD EIKEV P AAKKGGGR GGRKA
Subjt:  AVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS--EDDDDLEIKEVAPPAAKKGGGRGGGRKA

Query:  AAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPAR
        AAAN KTTK PAAG KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGS+LGR I       EEEEE+   +E K+MGSASSET+EEVAGF+PA 
Subjt:  AAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPAR

Query:  GRSQRANRTQVKYVVSDSESEAVSEDSDFDE-EASLDEE
        GRS+RANRTQV+YV+SDS+ EAVS+DSDFDE EASLDE+
Subjt:  GRSQRANRTQVKYVVSDSESEAVSEDSDFDE-EASLDEE

XP_008461811.1 PREDICTED: DNA topoisomerase 2 [Cucumis melo]

0.0e+00

91.16

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Query:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSN  NVDS PAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VFNDNMGKKSEPIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P+KSFQDYVDLYLKSAS+FQ EPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVK+YLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNPSFDSQTKETLTKR NSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATH+NGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLT+HKKDFIWQDDNDGEAIELAFSKKKIEDRKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRMLDGE MLPMDPWYRGFSGTIEKT+TK+GGT+YT+SGIIEEVSDTTLRI+ELPVRRWT+DYKDFLDSVTRVA+KH  DKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKR LL+NLEMELLKLENKVRFILAVVN EI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
         VSNR++VDLFHELQAKGFTPFPKKTKSVEPE+AGASNETDEAEESPE VKGER+SDYEYLLAL IGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA
        LNDLD+LEKELDE+DRNDAQ ME+RKQQR+K+NNDLKPKISRNAPKAPRNSKKT N ETVTESMDTT SS+TTEVANNPVVKPKGKAAPRKAPA KKGKA
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA

Query:  AVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS--EDDDDLEIKEVAPPAAKKGGGRGGGRKA
        AV D++D+DE+LELKDRLAAYKIESSPEPSEVSAMETEV +VQAAKKKEPSKRA  KKKTTAKSAQISIS  EDDDD EIKEV P AAKKGGGR GGRKA
Subjt:  AVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS--EDDDDLEIKEVAPPAAKKGGGRGGGRKA

Query:  AAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPAR
        AAAN KTTK PAAG KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGS+LGR I       EEEEE+   +E K+MGSASSET+EEVAGF+PA 
Subjt:  AAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPAR

Query:  GRSQRANRTQVKYVVSDSESEAVSEDSDFDE-EASLDEE
        GRS+RANRTQV+YV+SDS+ EAVS+DSDFDE EASLDE+
Subjt:  GRSQRANRTQVKYVVSDSESEAVSEDSDFDE-EASLDEE

XP_011651769.2 DNA topoisomerase 2 [Cucumis sativus]

0.0e+00

89.92

Show/hide

Query:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSN  NVDS PAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEN++MVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFS+EFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VFNDNMGKKSEPIITKCK GDNWT+VTFKPDL KFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P++SFQDYVDLYLKSAS+ Q EPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHV+YITNQIAN+VMT VNKKNKNANVKAHNVKSYLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNPSFDSQTKETLTKR NSFGSACELTP+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATH+NGTVLSFYTMPEYE+WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLT+HKKDFIWQDDNDGEAIELAFSKKKIEDRKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFP+DDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRML+GE MLPMDPWYRGFSGTIEKT+TK+GGT+YTVSGIIEEVSDTTLRI+ELPVRRWT+DYKDFLDSVTRVA+KHDKDKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKR LL+NLEMELLKLENKVRFILAVVN EI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
         VSNR++VDLFHELQAKGFTPFPKKTKSVEPE+AGASNETDEAEESPE VKGER+SDYEYLLAL IGTLTIEKVQELC+DRDKLKGEVDDLRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA
        LNDLD LEKELDEMDRNDAQ ME+RKQQREK+N DLKPK+SRNAPKAPRNSKKT N ETVTESMDTT SS+TTEVANNPVVKPKGKAAPRKAPA KKGKA
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA

Query:  AVLD---DEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQV--QAAKKKEPSKRAAPKKKTTAKSAQISISEDDD--DLEIKEVAPPAAKKGGGR-
        AVLD   D+++DE+LELKDRLAAYKIESSPEPSEVSAMETEV +V  QAAKKKEPSKRA  KKKTTAKSAQISIS+DD+  D EIKEV PPAAKKGGGR 
Subjt:  AVLD---DEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQV--QAAKKKEPSKRAAPKKKTTAKSAQISISEDDD--DLEIKEVAPPAAKKGGGR-

Query:  GGGRKAAAANAKTTKPPAAGVKLGQKLITQMLEP-AENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETTEEV
        GGGRKAAA N+KTTKPPAAG KLGQKLITQMLEP AENSGISPEKKVRKIRASPFNKKSGS+LGRTIGEEEE+E ++       E KLMGSAS ET+EEV
Subjt:  GGGRKAAAANAKTTKPPAAGVKLGQKLITQMLEP-AENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETTEEV

Query:  AGFRPARGRSQRANR-TQVKYVVSDSESEAVSEDSDFDE-EASLDEE
           + ARGRS+RANR TQV+YV+SDS+ E  S+DSDFDE EASLDE+
Subjt:  AGFRPARGRSQRANR-TQVKYVVSDSESEAVSEDSDFDE-EASLDEE

XP_022935016.1 DNA topoisomerase 2 isoform X2 [Cucurbita moschata]

0.0e+00

89.18

Show/hide

Query:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSN  NVDS PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VF+DNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P+KSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNP+FDSQTKETLT R +SFGSACELTP+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL +HKKDFIWQD++DGEAIELAFSKKKIE+RKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRML+GE MLPMDPWYRGFSGTIEKT+TK+GGTSYTVSGIIEEVSDTTLRI ELPVRRWTNDYKDFLDSVTRV+TK+DKDKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        K VSIDVHLTEENM+LA+QEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKVRFILAVVNGEI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
        IVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNETDEAEESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEV++LRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMD--TTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKA
        L DLD LEKELDEMDRNDAQA E+RKQQR K NND+KPKISRNAPKAPRNSKKT N+ET+TESMD  T+SS+TTEVANNPVVKPKGKAAPRKAPAKKGK 
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMD--TTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKA

Query:  AVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQ-AAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAA
        AVLDD+D+DE+LELKDRLAAYK+ESSPEPSEVSAMETEVP+VQ AAKKKEPSKRAA KKKTTAKSAQIS   DD D EIKE+APPAAKKGGGR      A
Subjt:  AVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQ-AAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAA

Query:  AANAKTTK-----PPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETT-EEVAG
        AANAKTTK      P A  +LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR IG     EEEEE EEAGNE K+MGSASSETT EEVA 
Subjt:  AANAKTTK-----PPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETT-EEVAG

Query:  FRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEE
           ARGRSQR NRTQV+YVVSDS+SE V EDSDFDEEA+LDE+
Subjt:  FRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEE

XP_038905935.1 DNA topoisomerase 2 [Benincasa hispida]

0.0e+00

91.34

Show/hide

Query:  MAVEKKRPLQNSNVTNVDSYP-AGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSM
        MAVEKKRPLQNSN  NVDS P AGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHRS+SYVPGLYKIFDEILVNAADNKQRDPSM
Subjt:  MAVEKKRPLQNSNVTNVDSYP-AGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSM

Query:  DSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTN
        DSVKV+IDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQ          
Subjt:  DSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTN

Query:  CSVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQR
                                     VFNDNMGKKSEPIITKCK GDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQR
Subjt:  CSVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQR

Query:  VPIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWV
        VPIKSFQDYVDLYLKSASTFQTEPPKRYHIKPN+RWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQI+NYVMT VNKKNKNANVKAHNVK+YLWV
Subjt:  VPIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWV

Query:  FINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG
        FINALIDNPSFDSQTKETLTKR NSFGS CELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG
Subjt:  FINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG

Query:  DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL
        DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA+SKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL
Subjt:  DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL

Query:  KVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRK
        +VPSFLVEFITPIVKATH+NGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLT+HKKDFIWQDDNDGEAIELAFSKKKIEDRK
Subjt:  KVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRK

Query:  NWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQD
        NWLRQFEPGTHLDQT KLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQD
Subjt:  NWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQD

Query:  FVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIR
        FVGSNNINLLLPNGQFGTRN GGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDII+
Subjt:  FVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIR

Query:  NVRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSD
        NVRRMLDG  MLPMDPWYRGFSGTIEKT+TK+GGTSYTVSGIIEEVSDT LRI+ELPVRRWTNDYKDFLDSVT+VATKHDKDKEKAAK+PFIEQADHHSD
Subjt:  NVRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSD

Query:  DKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGE
        DKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRL+FYEKRKRNLLENLEMELLKLENKVRFIL VVN E
Subjt:  DKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGE

Query:  IIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSL
        IIV NRR+VDLFHELQAKGFTPFPKK KSVEPEVAGAS+E DEAEESPE VK  RVSDYEYLL+L IGTLTIEKVQELCN+RDKLKGEVDDLRKATPK+L
Subjt:  IIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSL

Query:  WLNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSSSTT-EVANNPVVKPKGKAAPRKAPAKKGKA
        WLNDLD+LEKELDEMD NDAQAME RK+QR+K NNDLKPKISRNAPKAPRN KKT NAE VTESMDTT SSTT EVANNPVVKPKGKAAPRKAPAKKGKA
Subjt:  WLNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSSSTT-EVANNPVVKPKGKAAPRKAPAKKGKA

Query:  AVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS-----EDDDDLEIKEVAPPAAKKGGGRGGG
        AVLDD D+DE+LELKDRLAAYKIESSPEPSEVS METEVPQVQAAKKKEP+KRAA KKKTTAKSAQ+S+S     +DDDD E+KEVAPPA KKGGGRGGG
Subjt:  AVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS-----EDDDDLEIKEVAPPAAKKGGGRGGG

Query:  RKAAAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETT-EEVAGF
        RKAAA NAKTTKPPAA  KLGQKLIT+MLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIG  EE+EEEEEEEE+G EEK+MGSASSETT EEVAG 
Subjt:  RKAAAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETT-EEVAGF

Query:  RPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEE
         PARGRS RANRTQV+YVVSD +SE VSEDSD DE+
Subjt:  RPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEE

TrEMBL top hits

e value

%identity

Alignment

A0A1S3CFK5 DNA topoisomerase 2

0.0e+00

91.16

Show/hide

Query:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSN  NVDS PAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VFNDNMGKKSEPIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P+KSFQDYVDLYLKSAS+FQ EPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVK+YLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNPSFDSQTKETLTKR NSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATH+NGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLT+HKKDFIWQDDNDGEAIELAFSKKKIEDRKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRMLDGE MLPMDPWYRGFSGTIEKT+TK+GGT+YT+SGIIEEVSDTTLRI+ELPVRRWT+DYKDFLDSVTRVA+KH  DKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKR LL+NLEMELLKLENKVRFILAVVN EI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
         VSNR++VDLFHELQAKGFTPFPKKTKSVEPE+AGASNETDEAEESPE VKGER+SDYEYLLAL IGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA
        LNDLD+LEKELDE+DRNDAQ ME+RKQQR+K+NNDLKPKISRNAPKAPRNSKKT N ETVTESMDTT SS+TTEVANNPVVKPKGKAAPRKAPA KKGKA
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA

Query:  AVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS--EDDDDLEIKEVAPPAAKKGGGRGGGRKA
        AV D++D+DE+LELKDRLAAYKIESSPEPSEVSAMETEV +VQAAKKKEPSKRA  KKKTTAKSAQISIS  EDDDD EIKEV P AAKKGGGR GGRKA
Subjt:  AVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS--EDDDDLEIKEVAPPAAKKGGGRGGGRKA

Query:  AAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPAR
        AAAN KTTK PAAG KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGS+LGR I       EEEEE+   +E K+MGSASSET+EEVAGF+PA 
Subjt:  AAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPAR

Query:  GRSQRANRTQVKYVVSDSESEAVSEDSDFDE-EASLDEE
        GRS+RANRTQV+YV+SDS+ EAVS+DSDFDE EASLDE+
Subjt:  GRSQRANRTQVKYVVSDSESEAVSEDSDFDE-EASLDEE

A0A5A7TZH5 DNA topoisomerase 2

0.0e+00

91.16

Show/hide

Query:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSN  NVDS PAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VFNDNMGKKSEPIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P+KSFQDYVDLYLKSAS+FQ EPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVK+YLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNPSFDSQTKETLTKR NSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATH+NGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLT+HKKDFIWQDDNDGEAIELAFSKKKIEDRKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRMLDGE MLPMDPWYRGFSGTIEKT+TK+GGT+YT+SGIIEEVSDTTLRI+ELPVRRWT+DYKDFLDSVTRVA+KH  DKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKR LL+NLEMELLKLENKVRFILAVVN EI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
         VSNR++VDLFHELQAKGFTPFPKKTKSVEPE+AGASNETDEAEESPE VKGER+SDYEYLLAL IGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA
        LNDLD+LEKELDE+DRNDAQ ME+RKQQR+K+NNDLKPKISRNAPKAPRNSKKT N ETVTESMDTT SS+TTEVANNPVVKPKGKAAPRKAPA KKGKA
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTT-SSSTTEVANNPVVKPKGKAAPRKAPA-KKGKA

Query:  AVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS--EDDDDLEIKEVAPPAAKKGGGRGGGRKA
        AV D++D+DE+LELKDRLAAYKIESSPEPSEVSAMETEV +VQAAKKKEPSKRA  KKKTTAKSAQISIS  EDDDD EIKEV P AAKKGGGR GGRKA
Subjt:  AVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISIS--EDDDDLEIKEVAPPAAKKGGGRGGGRKA

Query:  AAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPAR
        AAAN KTTK PAAG KLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGS+LGR I       EEEEE+   +E K+MGSASSET+EEVAGF+PA 
Subjt:  AAANAKTTKPPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPAR

Query:  GRSQRANRTQVKYVVSDSESEAVSEDSDFDE-EASLDEE
        GRS+RANRTQV+YV+SDS+ EAVS+DSDFDE EASLDE+
Subjt:  GRSQRANRTQVKYVVSDSESEAVSEDSDFDE-EASLDEE

A0A6J1F3D6 DNA topoisomerase 2

0.0e+00

89.18

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Query:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSN  NVDS PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VF+DNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P+KSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNP+FDSQTKETLT R +SFGSACELTP+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL +HKKDFIWQD++DGEAIELAFSKKKIE+RKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRML+GE MLPMDPWYRGFSGTIEKT+TK+GGTSYTVSGIIEEVSDTTLRI ELPVRRWTNDYKDFLDSVTRV+TK+DKDKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        K VSIDVHLTEENM+LA+QEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKVRFILAVVNGEI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
        IVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNETDEAEESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEV++LRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMD--TTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKA
        L DLD LEKELDEMDRNDAQA E+RKQQR K NND+KPKISRNAPKAPRNSKKT N+ET+TESMD  T+SS+TTEVANNPVVKPKGKAAPRKAPAKKGK 
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMD--TTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKA

Query:  AVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQ-AAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAA
        AVLDD+D+DE+LELKDRLAAYK+ESSPEPSEVSAMETEVP+VQ AAKKKEPSKRAA KKKTTAKSAQIS   DD D EIKE+APPAAKKGGGR      A
Subjt:  AVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQ-AAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAA

Query:  AANAKTTK-----PPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETT-EEVAG
        AANAKTTK      P A  +LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR IG     EEEEE EEAGNE K+MGSASSETT EEVA 
Subjt:  AANAKTTK-----PPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETT-EEVAG

Query:  FRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEE
           ARGRSQR NRTQV+YVVSDS+SE V EDSDFDEEA+LDE+
Subjt:  FRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEE

A0A6J1F9E0 DNA topoisomerase 2

0.0e+00

89.12

Show/hide

Query:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVEKKRPLQNSN  NVDS PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VF+DNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P+KSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNP+FDSQTKETLT R +SFGSACELTP+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL +HKKDFIWQD++DGEAIELAFSKKKIE+RKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRML+GE MLPMDPWYRGFSGTIEKT+TK+GGTSYTVSGIIEEVSDTTLRI ELPVRRWTNDYKDFLDSVTRV+TK+DKDKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        K VSIDVHLTEENM+LA+QEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKVRFILAVVNGEI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
        IVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNETDEAEESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEV++LRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMD--TTSSSTTEVANNPVVKPKGKAAPRKAPAKK-GK
        L DLD LEKELDEMDRNDAQA E+RKQQR K NND+KPKISRNAPKAPRNSKKT N+ET+TESMD  T+SS+TTEVANNPVVKPKGKAAPRKAPAKK GK
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMD--TTSSSTTEVANNPVVKPKGKAAPRKAPAKK-GK

Query:  AAVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQ-AAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKA
         AVLDD+D+DE+LELKDRLAAYK+ESSPEPSEVSAMETEVP+VQ AAKKKEPSKRAA KKKTTAKSAQIS   DD D EIKE+APPAAKKGGGR      
Subjt:  AAVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQ-AAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKA

Query:  AAANAKTTK-----PPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETT-EEVA
        AAANAKTTK      P A  +LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR IG     EEEEE EEAGNE K+MGSASSETT EEVA
Subjt:  AAANAKTTK-----PPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETT-EEVA

Query:  GFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEE
            ARGRSQR NRTQV+YVVSDS+SE V EDSDFDEEA+LDE+
Subjt:  GFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEE

A0A6J1J555 DNA topoisomerase 2

0.0e+00

89.11

Show/hide

Query:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MAVE KRPLQNSN  NVDS PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLW+YEND+MVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        S+KV ID EQNCISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VF+DNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
        P+KSFQDYVD YLKSA+ FQTEPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGI+TIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF
Subjt:  PIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVF

Query:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
        INALIDNP+FDSQTKETLT R +SFGSACELTP+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD
Subjt:  INALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGD

Query:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK
        SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY+NAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL+
Subjt:  SAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLK

Query:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN
        VPSFLVEFITPIVKATHRNGTVLSFYTMPEYE+WK++LRGNASGWSIKYYKGLGTSTSKEGREYFEQL +HKKDFIWQD++DGEAIELAFSKKKIE+RKN
Subjt:  VPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKN

Query:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
        WLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNF+KEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF
Subjt:  WLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDF

Query:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN
        VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRN
Subjt:  VGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRN

Query:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD
        VRRMLDGE MLPMDPWYRGFSGTIEKT+TK+GGTSYTVSGIIEEVSDTTLRI ELPVRRWTNDYKDFLDSVTRV+TK+DKDKEKAAKDPFIEQADHHSDD
Subjt:  VRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDD

Query:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
        K VSI+VHLTEENM+LA+QEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEF+EKRKRNLLENLE ELLKLENKVRFILAVVNGEI
Subjt:  KIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI

Query:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW
        IVSNRRRVDLFHELQ KGFTPFPKKTKSVEPEVAGASNETDEAEESPE VKGERVSDYEYLLALAIGTLTIEKVQELCN+RDK KGEV++LRKATPKSLW
Subjt:  IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLW

Query:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMD--TTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKA
        L DLD LEKELDEMDRNDAQA E+RKQQR K NND+KPKISRNAPKAPRNSKKT N+ET+TESMD  T+SS+TTEVANNPVVKPKGKAAPRKAPAKKGKA
Subjt:  LNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMD--TTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKA

Query:  AVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQ-AAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAA
        AVLDD+ +DE+LELKDRLAAYK+ESSPEPSEVSAMETEVP+VQ AAKKKEPSKRAA KKKTTAKSAQIS   DD D EIKE+APPAAKKGGGR      A
Subjt:  AVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQ-AAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAA

Query:  AANAKTTK-----PPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETT-EEVAG
        AANAKTTK      P A  +LGQKLITQMLEP ENSGISPEKKVRKIR SPFNKKSGS+LGR IG     EEEEE EEAGNE K+MGSASSETT EEVA 
Subjt:  AANAKTTK-----PPAAGVKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETT-EEVAG

Query:  FRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEE
           ARGRSQR NRTQV+YVVSDS+SE V EDSDFDEEA LDE+
Subjt:  FRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEE

SwissProt top hits

e value

%identity

Alignment

O24308 DNA topoisomerase 2

0.0e+00

61.59

Show/hide

Query:  KKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKV
        +KRPLQ SN  N+      P KTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYEND MVHR++SYVPGLYKIFDEILVNAADNKQRDPSMDS+KV
Subjt:  KKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKV

Query:  NIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNCSVDF
         ID E N +SV+NNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADG+R+KKYKQ               
Subjt:  NIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNCSVDF

Query:  ELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIKS
                                VF++NMG K EP+ITKCK  +NWTKVTFKPDL KF M +LE+DVVALMKKRVLD+AGC GKTVKVELNG  +  KS
Subjt:  ELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIKS

Query:  FQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINAL
        F+DY DL+LK A   +  P  R H K  +RWEI ++LS+GQFQQVSFVN I+TIKGGTHVDYITNQI  Y+M  VNKK K+ANVKAH VK++LWVF+N+L
Subjt:  FQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINAL

Query:  IDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKA
        IDNP+FDSQTKETLT R  SFGS C++    LK+V  KSGI+D++LSW +FKQSKDLKKTDG KT+++ G  K EDAN AGG+NSEKCTLILTEGDSAKA
Subjt:  IDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKA

Query:  LAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSF
        LAMAGL VVGRD YGVFPLRGKLLNVREASSKQI +N+EIQ IK+ILGLQQ KEY+N K+LRYGHLMIM DQDHDGSHIKGLLINFIHSFWPSLLKVPSF
Subjt:  LAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSF

Query:  LVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQ
        LVEF TP+++A+H N T+ SFY+MPEYE+WKE L  +A+ W IKYYKGLGTST +EGREYF  L RH+KDFIW D+ DG AIELAFSKKK E RK W+R 
Subjt:  LVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQ

Query:  FEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSN
        FEPGT  D   KLI Y DFVNKELILFS AD                   LF SFK+   KE KV+QF GYVSEHSAYHHGEQSLASTIIGMAQDFVGSN
Subjt:  FEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSN

Query:  NINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRM
        NINLL PNGQFGT N GGKDHAS+RYIYT+LS VTR LF + DDKLL YLNEDG+SIEP WYMPIIP VLVNGSEGIGTGWSSY+PNYNPR+II NVRR+
Subjt:  NINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRM

Query:  LDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDDKIVS
        L+GE ++PMDPWY+GF GTIEK S K+GG  Y V+G + E+ + T RI ELP+R+WT DYK FL+S+T        D     KDP IE    + DD IV 
Subjt:  LDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDDKIVS

Query:  IDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSN
        I++ +  E +   +QEGL KKFKLT+T+STSNMHLFDA G  KK+DTPEQILEEFFPLRL++YEK K  +L NL   LL L+NKVRFIL VVNGEIIVSN
Subjt:  IDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSN

Query:  RRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEE--SPET------VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATP
        R++ +L  EL+ KGFTP P+K KS +P+VAGA+++  E +E   PET      V+G    DY+ LL+L IGTLT+E VQ+L +++ + + E + L     
Subjt:  RRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEE--SPET------VKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATP

Query:  KSLWLNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSSSTTEVAN-NPVVKPKGKAAPRKAPAKK
         SLWL DLD  EK+LDE+D   A+    R  Q  K  N    K ++  P+  +N+KK  + E   ++      +  E A    V KPKG+AAP+K     
Subjt:  KSLWLNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSSSTTEVAN-NPVVKPKGKAAPRKAPAKK

Query:  GKAAVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTT-------AKSAQISISEDDDDL-EIKEVAPPAAKKG
             +  E ED+I  L++RLAAY IESS E S+  AME+E  Q +AA KK+ +KR   KKK++       + +    + +DDDD  E+++ A P  K  
Subjt:  GKAAVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTT-------AKSAQISISEDDDDL-EIKEVAPPAAKKG

Query:  GGRGGGRKAAAANAK------TTKPPAAGVK--------LGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGN
            GGRK AA NAK        K PAA  K         GQKL+T ML+PAE +G SPEKKVRK+R SPFNKKSGSILGR    ++     +    + +
Subjt:  GGRGGGRKAAAANAK------TTKPPAAGVK--------LGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGN

Query:  EEKLMGSASSETTEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED
           L    S +   E+A  +PAR R QRANRTQ+KY +S+SESE   EDSD D E S  EED
Subjt:  EEKLMGSASSETTEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED

O46374 DNA topoisomerase 2-alpha

0.0e+00

46.68

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Query:  MAVEKKRPLQNSNVTNVDSYPAGPKK--TIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMV-HRSISYVPGLYKIFDEILVNAADNKQRDP
        M V   +P+  +   N        KK  +IE +YQKK+QLEHILLRPDTY+GS+E  TQ +WVY+ D  + +R +++VPGLYKIFDEILVNAADNKQRDP
Subjt:  MAVEKKRPLQNSNVTNVDSYPAGPKK--TIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMV-HRSISYVPGLYKIFDEILVNAADNKQRDP

Query:  SMDSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISS
         M  ++V ID E N IS++NNG G+PV  H+ EK+YVP LIFG LLTSSNYDD EKK TGGRNGYGAKL NIFST+F +ETA  +  K +KQ        
Subjt:  SMDSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISS

Query:  TNCSVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNG
                                        + DNMG+  E +  K   G+++T +TF PDL+KF M  L+ D+VALM +R  D+AG   K VKV LNG
Subjt:  TNCSVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNG

Query:  QRVPIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNK-NANVKAHNVKSY
         ++P+K F+ YVDLYLK        P K  H + N RWE+ +T+SE  FQQ+SFVN I+T KGG HVDY+ +QI   ++ VV KKNK    VKAH VK++
Subjt:  QRVPIKSFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNK-NANVKAHNVKSY

Query:  LWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLI
        +W+F+NALI+NP+FDSQTKE +T +  SFGS C+L+ +F+K  A   GI++S+L+WV FK    L KK    K  +I GI KL+DAN AGG+NS +CTLI
Subjt:  LWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLI

Query:  LTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY---SNAKALRYGHLMIMTDQDHDGSHIKGLLINFIH
        LTEGDSAK LA++GLGVVGRD YGVFPLRGK+LNVREAS KQI EN EI  I +I+GLQ  K Y    + K LRYG +MIMTDQD DGSHIKGLLINFIH
Subjt:  LTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEY---SNAKALRYGHLMIMTDQDHDGSHIKGLLINFIH

Query:  SFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSK
          WPSLL+   FL EFITPIVK + +N   ++FY++PE+E WK S   N   W +KYYKGLGTSTSKE +EYF  + RH+  F +    D  AI LAFSK
Subjt:  SFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSK

Query:  KKIEDRKNWLRQFE-----------PGTHL-DQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHS
        K+I+DRK WL  F            P  +L  QT   + Y+DF+NKELILFS +D +RSIPSMVDGLKPGQRK+LF  FKRN  +E KV+Q +G V+E S
Subjt:  KKIEDRKNWLRQFE-----------PGTHL-DQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHS

Query:  AYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEG
        +YHHGE SL  TII +AQ+FVGSNN+NLL P GQFGTR HGGKD AS RYI+T LS + R LFP  DD  L +L +D Q +EP WY+PIIP VL+NG+EG
Subjt:  AYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEG

Query:  IGTGWSSYVPNYNPRDIIRNVRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDK
        IGTGWS  +PN++ R+++ N+R ++DGE  LPM P Y+ F GTIE+ +       Y +SG +  ++ TT+ I ELP+R WT  YK+      +V      
Subjt:  IGTGWSSYVPNYNPRDIIRNVRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDK

Query:  DKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEM
          EK    P I     +  D  V   V +TEE +  A + GL K FKL T+++ ++M LFD  G +KKYDT   IL +FF LRL++Y  RK  LL  L  
Subjt:  DKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEM

Query:  ELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSD----YEYLLALAIGTLTIEKVQE
        E  KL N+ RFIL  ++G+II+ N+ + +L   L  +G+   P K      +      E +E++   E  K + V+D    + YLL + +  LT EK  E
Subjt:  ELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSD----YEYLLALAIGTLTIEKVQE

Query:  LCNDRDKLKGEVDDLRKATPKSLWLNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSSSTTEVAN
        LC  R++ + E++ L++ +P  LW  DL A  +EL        +A+E +++Q E        +I           KKT  AE +       S     V  
Subjt:  LCNDRDKLKGEVDDLRKATPKSLWLNDLDALEKELDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSSSTTEVAN

Query:  NPVVKPKGKAAPR-KAPAKKGKAAVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLE
           V+ K +A  + K   K         ED  E+  LK RL   + +   EP   +  +T +P        +P K+A  KK+     ++  IS D+ +  
Subjt:  NPVVKPKGKAAPR-KAPAKKGKAAVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLE

Query:  IKEVAPPAAKKGGGRGGGRKAAAANAKTT
        +    PP  K+        + AAA  K T
Subjt:  IKEVAPPAAKKGGGRGGGRKAAAANAKTT

P08096 DNA topoisomerase 2

0.0e+00

45.94

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Query:  IEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVY--ENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQNCISVFNNGDGVPVE
        +   YQ+ +  EH+L RPDTY+GSIE  T  +WV+  E +++ +++++YVPGLYKIFDEI+VNAADNK RDP+M+++KV +D E N IS++NNG G+P+E
Subjt:  IEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVY--ENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQNCISVFNNGDGVPVE

Query:  IHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNCSVDFELILSCMFDSYSFAEPHLKNY
        IH +EK+Y+PELIFG+LLTSSNYDD +KK TGGRNGYGAKL NIFSTEFV+ETAD +RMKKYKQ                                    
Subjt:  IHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNCSVDFELILSCMFDSYSFAEPHLKNY

Query:  SFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIKSFQDYVDLYLKSASTFQTEPPK
            + DNM +KSEP+IT  K+ D +TK+TFKPDLAKF M  ++DD+V+++K+R+ D+AG + +T KV LN +R+ I  F+ YV++YL S +    EPP+
Subjt:  SFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIKSFQDYVDLYLKSASTFQTEPPK

Query:  RYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSF
          +   N+RW++   +S+GQF+QVSFVN ISTI+GGTHV+Y+ N+I + +  VV K+NK A VKA  +K+Y+ VF+N  I+NPSFDSQTKETLT + ++F
Subjt:  RYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSF

Query:  GSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRG
        GS C L+ +FLK +  KS +++ VL +   K  + L K DG    +I+G+ KLEDAN AG K S KC LILTEGDSAK+LA++GL VVGRD+YGVFPLRG
Subjt:  GSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRG

Query:  KLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSF
        KLLNVREAS  QI  NKEIQ IK+I+G    K Y++ K LRYGHLMIMTDQDHDGSHIKGL+IN++ S +PSLL++P FL++FITPI+K T R   V +F
Subjt:  KLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSF

Query:  YTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVN
        YT+PEYE WKE+   N  GW IKYYKGLGTS   + + YF  L RH K F    + D E IE+AF+KKK + RK WLR + PG ++D T   I   DF+N
Subjt:  YTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVN

Query:  KELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDH
        +ELI FSMAD  RSIPS+VDGLKPGQRK+++  FKRN V E KVS+ +GYV+  +AYHHGE S+  TI+ +AQ+FVGSNNINLL+PNGQFGTR+ GGK+ 
Subjt:  KELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDH

Query:  ASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGEMMLPMDPWYRGFSGTIE
        ++SRY+ T LS + R LF  +DD+LLNY N++GQ IEP +Y+PI+P VLVNG+EGIGTGWS+++PNYNP+DI  N+R ML+GE +  M PWYRGF G+I 
Subjt:  ASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGEMMLPMDPWYRGFSGTIE

Query:  KTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKK
           TK     Y +SGII ++ +  + I ELP+R WT D K++L++   V T      EK  K  FI   + H  +  V  +V LTE  M  A+ E L+ K
Subjt:  KTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKK

Query:  FKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPF--P
        FKL+ T +TSNM  FDA+G IKKYD+ E IL EF+ +RL  Y++RK +++  LE    +  N+ RFI  ++ GE++VS +++ DL  EL+ K F P   P
Subjt:  FKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPF--P

Query:  KKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDALEKELDEMDRNDAQAME
        KK   V+ EV    N   E E+S +  + E    Y YLL++ + +LT E+  EL   +D++  E+D L K TPK LWL+DLDA E   +++  +D Q   
Subjt:  KKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDALEKELDEMDRNDAQAME

Query:  IRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKAAVLDDEDEDEILELKDRLAAYKIES
        + ++Q  +   +   K  R      R  +    + + T      SS +     N   +   + A  K P K     ++  ED    L +++   +     
Subjt:  IRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKAAVLDDEDEDEILELKDRLAAYKIES

Query:  SPEPSEVSAMETEVPQVQAAKKKEPSKRAAP------KKKTTAKSAQISISEDDDDLEIKEVAPP--AAKKGGGRGGGRKAAAANAKTTKPP-----AAG
            S  S   ++    + A  K+P K+ A       +K     +  I  S+D+DDL    + P    + K   +  G+KA++   ++ +         G
Subjt:  SPEPSEVSAMETEVPQVQAAKKKEPSKRAAP------KKKTTAKSAQISISEDDDDLEIKEVAPP--AAKKGGGRGGGRKAAAANAKTTKPP-----AAG

Query:  VKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEE
             K  +   EP E+S  SP +K R  R +    K+   +  +    +E   +++     N+E
Subjt:  VKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEE

P30182 DNA topoisomerase 2

0.0e+00

61.01

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Query:  KRPLQNSNVTNVDSYPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSN  NV   PA  +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ LWVYE D MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNVTNVDSYPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADGKR+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VF +NMGKKSEP+ITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWV
        P+KSF DYVDLYL +A+  +TE P  R   K N+RWE+ V+LSEGQFQQVSFVN I+TIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWV
Subjt:  PIKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWV

Query:  FINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG
        F+NALIDNP+FDSQTKETLT R +SFGS CEL+ +FLK V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEG
Subjt:  FINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG

Query:  DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL
        DSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QIT NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL
Subjt:  DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL

Query:  KVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIED
        +VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WKESL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE 
Subjt:  KVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIED

Query:  RKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA
        RKNWL  + PG HLDQ    + YSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMA
Subjt:  RKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA

Query:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI
        QD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I
Subjt:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI

Query:  IRNVRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHH
        + NVRR+L+GE M+PMDPWYRGF GTIEKT++K+GG +YT++G+ EEV +TT+RI ELP+RRW +DYK+FL S+     K D         PF +    +
Subjt:  IRNVRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHH

Query:  SDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVN
        +D+K V  D+ L+EENML A QEG  KKFKLTTT++TSNMHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  +++N+E+ELLKLENK RFILAV++
Subjt:  SDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVN

Query:  GEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERV--------SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVD
        GEIIV+ R++ D+  +L+ KGFTPFP+K +SVE  +AGA +  D+A E PE +  +          S+Y+YLLA+AI +LTIEKV+EL  DRDK+   V 
Subjt:  GEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERV--------SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVD

Query:  DLRKATPKSLWLNDLDALEKELDEMDRNDAQAMEI--RKQQREKSNNDLKPKISRNAPKAP---RNSKKTINAETVTES---MDT---------------
        D++K TPKSLWL+DL++L+KEL+++D  DAQ  +     Q++ ++ +    K+ R APK P   + +KK   +ET   S   MDT               
Subjt:  DLRKATPKSLWLNDLDALEKELDEMDRNDAQAMEI--RKQQREKSNNDLKPKISRNAPKAP---RNSKKTINAETVTES---MDT---------------

Query:  -----TSSSTTEVANN---------PVVKPKGKAAPRKAPAKKGKAAVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRA
             + S TTE +++          VVKPKG+       AKK   A   + +EDE+L+L  RLA Y   S+P                           
Subjt:  -----TSSSTTEVANN---------PVVKPKGKAAPRKAPAKKGKAAVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRA

Query:  APKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAAAANAKTTKPPAAGVKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPFNKKSGS
        A   KT   S  I++ +DDDD+ + EVAP   KK     GGRK AA   K  KPPAA  K G++ +  T++L      G+SPEKKVRK+R+SPFNKKS S
Subjt:  APKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAAAANAKTTKPPAAGVKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPFNKKSGS

Query:  ILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED
        ++ R     + +EEE  E  AGN           ++E+  G   A  R QRANR ++ YV+SDSESE+ + DS+FD+    DE+D
Subjt:  ILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED

Q55BP5 Probable DNA topoisomerase 2

0.0e+00

45.83

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Query:  EKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVK
        +K     N NV    +  A   K+IEE+YQKK  L+ ILLRPDTY+GS E+  + LWV+E+ RMVHR +S+VPG+YKIFDEILVNAADNKQR+ +M  +K
Subjt:  EKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVK

Query:  VNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNCSVD
        V ID E+  ISV N+G G+P+++H E K+Y+PELIFG+LLTSS+YDD+EK+ TGGRNG+GAKL NIFST+F++E AD K  K YKQ              
Subjt:  VNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNCSVD

Query:  FELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIK
                                  F +NM  K +P IT  +   ++TK+TF P+L +F M   +DD+VAL+ KRV D+AGC   T+KV LN + + I+
Subjt:  FELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIK

Query:  SFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLS-EGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNK-NANVKAHNVKSYLWVFI
        SF+ Y++LY       +   PK Y+ K ++RWE+ VTLS E QF QVSFVN I T+KGGTHV +  + I   +   VNKKNK +A++K   +K++L VF+
Subjt:  SFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLS-EGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNK-NANVKAHNVKSYLWVFI

Query:  NALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVA-TKSGIMDSVLSWVNFKQSKDLKK--TDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTE
        N LI+NP FDSQTKETLT + +SFGS CE + +F+K V  +KSGI+ S+L +  FK    LK+  + G K  K+S I KL+DAN AGG  SE CTLILTE
Subjt:  NALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVA-TKSGIMDSVLSWVNFKQSKDLKK--TDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTE

Query:  GDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSL
        GDSAK+LA AG+ VVG+D YG FPL+GKLLNVR+ S+K +  N EI  I  ILGL+ GK Y     LRYGHLMIMTDQDHDGSHIKGL+IN +H FWP+L
Subjt:  GDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSL

Query:  LKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDR
        L++P FLVEFITPIVK    N   +SFYTMPE+  W+E+   N  GW +KYYKGLGTST  EG+EYF  L RHK DF W D+   + IELAFSK + +DR
Subjt:  LKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDR

Query:  KNWLRQFEPGTHLDQTG-KLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA
        K W+ +   GT L+Q G K + YSDF+NKEL+LFS+AD +RSIP++VDGLK   RK L+  FKRN  KE KV+Q  GYVSEHSAYHHGE SL STI+GMA
Subjt:  KNWLRQFEPGTHLDQTG-KLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA

Query:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI
        Q+FVGSNNINLL P G +GTR  GGKD +S+RYI+T+L+++ R ++  DDD +L+ + +DG+ ++P +Y+P+IP +LVNG  GIGTGWSS +PNYNPRD+
Subjt:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI

Query:  IRNVRRMLDGEMMLPMDPWYRGFSGTIE-KTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSV----TRVATKHDKDKEKA------A
        I+N+R  +DG+ + P+ PWYRGF G+IE    +K  G  Y   GI +++SD    I ELP+  WT DY++ LD +    TR   K +K+K+ A      A
Subjt:  IRNVRRMLDGEMMLPMDPWYRGFSGTIE-KTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSV----TRVATKHDKDKEKA------A

Query:  KDPFIEQADHHSDD----KIVSIDV------------HLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKR
        K    +++    DD    K+    V            H   + +    +  ++K FKL +T++ +NM +FD  G I+++ T   + E FFPLR++ Y+ R
Subjt:  KDPFIEQADHHSDD----KIVSIDV------------HLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKR

Query:  KRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKK--TKSVEPEVAGASNETDE------AEESPETVKGERVSD---YE
        K  L E L  E  +L NK RFILAVVN E+++SN ++VDL ++L+   F     K   KS   ++    N  DE      ++E  +  + E+  D   Y+
Subjt:  KRNLLENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKK--TKSVEPEVAGASNETDE------AEESPETVKGERVSD---YE

Query:  YLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDALEKELDEMDRNDA----QAMEIRKQQREKS---NNDLKPKISRNAPKAPRNS-
        YLL+L + +LT+E+V++L  +RD  K E D L     + ++  DLDALEK LD+ D  D     Q   ++K+ + K+      +  K+ ++  +AP    
Subjt:  YLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDALEKELDEMDRNDA----QAMEIRKQQREKS---NNDLKPKISRNAPKAPRNS-

Query:  -KKTINAETVTESM----------DTTSSSTTEVANN---PVVKPKGKAAPRKAPA-KKGKAAVLD---DEDEDEILELKDRLAAYKIESSPEPSEVSAM
         K T+   T T+S           DTTS+ST+   ++   P+     K   +  PA KK     LD   D D+D ++  K +    K     E S+ S  
Subjt:  -KKTINAETVTESM----------DTTSSSTTEVANN---PVVKPKGKAAPRKAPA-KKGKAAVLD---DEDEDEILELKDRLAAYKIESSPEPSEVSAM

Query:  ETEVPQVQAAKKKEPSKRA----------APKKKTTAKSAQISISEDDDDL
        E++    Q +  + P KR+          A KK TT+KS  I     DD++
Subjt:  ETEVPQVQAAKKKEPSKRA----------APKKKTTAKSAQISISEDDDDL

Arabidopsis top hits

e value

%identity

Alignment

AT3G10270.1 DNA GYRASE B1

3.6e-20

23.2

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Query:  GLYKIFDEILVNAADNKQRDPSMDSVKVNIDV---EQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFS
        GL+ +  EIL NA D  Q           IDV     + +S+ +NG G+P ++H        E +   L     +         +GG +G G  + N  S
Subjt:  GLYKIFDEILVNAADNKQRDPSMDSVKVNIDV---EQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFS

Query:  TEF-VIETADGKRMKKYKQKEVISISSTNCSV-----------------DFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTK
            VI   DG   ++ K      +++  C V                 D E+  + +   ++     ++  +F      +  K E       E D +++
Subjt:  TEF-VIETADGKRMKKYKQKEVISISSTNCSV-----------------DFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTK

Query:  VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIK---SFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVS
          +   L ++ ++ L  D     KK + D+ G      + E+NG  V +        Y D  L  A++ +T      HI+   +  +  TL+       S
Subjt:  VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIK---SFQDYVDLYLKSASTFQTEPPKRYHIKPNERWEIVVTLSEGQFQQVS

Query:  FVNGISTIKGGTHVDY----------ITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETL----------TKRPNSFGSACE
            +  IK   ++ Y           ++ +  + +  +N + K+ ++   +V+  L   ++  + NP F+ QTK  L                     E
Subjt:  FVNGISTIKGGTHVDY----------ITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETL----------TKRPNSFGSACE

Query:  LTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN
        L P+ L+++ +KS  +++  + +  K++++L ++    K+  + G  KL D +      SE   + + EGDSA   A  G     R F  + PLRGK+LN
Subjt:  LTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLN

Query:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMP
        +       + +N+EIQ +   LGL    E  N + LRY  ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K   R       Y   
Subjt:  VREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMP

Query:  EYESWKESLRGNASGWSIKYYKGLG
          +    S  GNAS ++I+ +KGLG
Subjt:  EYESWKESLRGNASGWSIKYYKGLG

AT3G23890.1 topoisomerase II

0.0e+00

61.01

Show/hide

Query:  KRPLQNSNVTNVDSYPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSN  NV   PA  +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ LWVYE D MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNVTNVDSYPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADGKR+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VF +NMGKKSEP+ITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWV
        P+KSF DYVDLYL +A+  +TE P  R   K N+RWE+ V+LSEGQFQQVSFVN I+TIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWV
Subjt:  PIKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWV

Query:  FINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG
        F+NALIDNP+FDSQTKETLT R +SFGS CEL+ +FLK V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEG
Subjt:  FINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG

Query:  DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL
        DSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QIT NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL
Subjt:  DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL

Query:  KVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIED
        +VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WKESL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE 
Subjt:  KVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIED

Query:  RKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA
        RKNWL  + PG HLDQ    + YSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMA
Subjt:  RKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA

Query:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI
        QD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I
Subjt:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI

Query:  IRNVRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHH
        + NVRR+L+GE M+PMDPWYRGF GTIEKT++K+GG +YT++G+ EEV +TT+RI ELP+RRW +DYK+FL S+     K D         PF +    +
Subjt:  IRNVRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHH

Query:  SDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVN
        +D+K V  D+ L+EENML A QEG  KKFKLTTT++TSNMHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  +++N+E+ELLKLENK RFILAV++
Subjt:  SDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVN

Query:  GEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERV--------SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVD
        GEIIV+ R++ D+  +L+ KGFTPFP+K +SVE  +AGA +  D+A E PE +  +          S+Y+YLLA+AI +LTIEKV+EL  DRDK+   V 
Subjt:  GEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERV--------SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVD

Query:  DLRKATPKSLWLNDLDALEKELDEMDRNDAQAMEI--RKQQREKSNNDLKPKISRNAPKAP---RNSKKTINAETVTES---MDT---------------
        D++K TPKSLWL+DL++L+KEL+++D  DAQ  +     Q++ ++ +    K+ R APK P   + +KK   +ET   S   MDT               
Subjt:  DLRKATPKSLWLNDLDALEKELDEMDRNDAQAMEI--RKQQREKSNNDLKPKISRNAPKAP---RNSKKTINAETVTES---MDT---------------

Query:  -----TSSSTTEVANN---------PVVKPKGKAAPRKAPAKKGKAAVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRA
             + S TTE +++          VVKPKG+       AKK   A   + +EDE+L+L  RLA Y   S+P                           
Subjt:  -----TSSSTTEVANN---------PVVKPKGKAAPRKAPAKKGKAAVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRA

Query:  APKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAAAANAKTTKPPAAGVKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPFNKKSGS
        A   KT   S  I++ +DDDD+ + EVAP   KK     GGRK AA   K  KPPAA  K G++ +  T++L      G+SPEKKVRK+R+SPFNKKS S
Subjt:  APKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAAAANAKTTKPPAAGVKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPFNKKSGS

Query:  ILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED
        ++ R     + +EEE  E  AGN           ++E+  G   A  R QRANR ++ YV+SDSESE+ + DS+FD+    DE+D
Subjt:  ILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED

AT3G23890.2 topoisomerase II

0.0e+00

62.14

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Query:  KRPLQNSNVTNVDSYPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSN  NV   PA  +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ LWVYE D MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNVTNVDSYPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADGKR+KKYKQ           
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNC

Query:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV
                                    VF +NMGKKSEP+ITKC + +NWTKVTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++
Subjt:  SVDFELILSCMFDSYSFAEPHLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRV

Query:  PIKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWV
        P+KSF DYVDLYL +A+  +TE P  R   K N+RWE+ V+LSEGQFQQVSFVN I+TIKGGTHVDY+T+QI N+++  VNKKNKNANVKAHNVK++LWV
Subjt:  PIKSFQDYVDLYLKSASTFQTEPP-KRYHIKPNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWV

Query:  FINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG
        F+NALIDNP+FDSQTKETLT R +SFGS CEL+ +FLK V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEG
Subjt:  FINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEG

Query:  DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL
        DSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QIT NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL
Subjt:  DSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLL

Query:  KVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIED
        +VPSFLVEFITPIVKAT R GT  VLSFY+MPEYE WKESL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE 
Subjt:  KVPSFLVEFITPIVKATHRNGT--VLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIED

Query:  RKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA
        RKNWL  + PG HLDQ    + YSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMA
Subjt:  RKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMA

Query:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI
        QD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I
Subjt:  QDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDI

Query:  IRNVRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHH
        + NVRR+L+GE M+PMDPWYRGF GTIEKT++K+GG +YT++G+ EEV +TT+RI ELP+RRW +DYK+FL S+     K D         PF +    +
Subjt:  IRNVRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPFIEQADHH

Query:  SDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVN
        +D+K V  D+ L+EENML A QEG  KKFKLTTT++TSNMHLFD  GVIKKY TPEQILEEFF LR E+YEKRK  +++N+E+ELLKLENK RFILAV++
Subjt:  SDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVN

Query:  GEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERV--------SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVD
        GEIIV+ R++ D+  +L+ KGFTPFP+K +SVE  +AGA +  D+A E PE +  +          S+Y+YLLA+AI +LTIEKV+EL  DRDK+   V 
Subjt:  GEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERV--------SDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVD

Query:  DLRKATPKSLWLNDLDALEKELDEMDRNDAQAMEI--RKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSS-STTEVANN--PVVKPKG
        D++K TPKSLWL+DL++L+KEL+++D  DAQ  +     Q++ ++ +    K+ R APK P   K T  A   +ES  T +S S  +  NN   VVKPKG
Subjt:  DLRKATPKSLWLNDLDALEKELDEMDRNDAQAMEI--RKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSS-STTEVANN--PVVKPKG

Query:  KAAPRKAPAKKGKAAVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAA
        +       AKK   A   + +EDE+L+L  RLA Y   S+P                           A   KT   S  I++ +DDDD+ + EVAP   
Subjt:  KAAPRKAPAKKGKAAVLDDEDEDEILELKDRLAAYKIESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAA

Query:  KKGGGRGGGRKAAAANAKTTKPPAAGVKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSAS
        KK     GGRK AA   K  KPPAA  K G++ +  T++L      G+SPEKKVRK+R+SPFNKKS S++ R     + +EEE  E  AGN         
Subjt:  KKGGGRGGGRKAAAANAKTTKPPAAGVKLGQKLI--TQMLEPAENSGISPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSAS

Query:  SETTEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED
          ++E+  G   A  R QRANR ++ YV+SDSESE+ + DS+FD+    DE+D
Subjt:  SETTEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED

AT5G04130.1 DNA GYRASE B2

6.5e-22

27.41

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Query:  VSFVNGISTIKGGTHVDYITNQIANYVMTVVNK----KNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETL----------TKRPNSFGSACELTPE
        + + N I TI GGTH++ +   +   + T+  K    K K+ ++   +V+  L   ++  + NP F+ QTK  L                     EL P+
Subjt:  VSFVNGISTIKGGTHVDYITNQIANYVMTVVNK----KNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETL----------TKRPNSFGSACELTPE

Query:  FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA
         L+++ +KS  +++  + +  K++++L ++    K+  + G  KL D +    + SE   + + EGDSA   A  G     R F  + PLRGK+LN+   
Subjt:  FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA

Query:  SSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES
            + +N+EIQ +   LGL    E    + LRY  ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K   R       Y   + + 
Subjt:  SSKQITENKEIQYIKQILGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYES

Query:  WKESLRGNASGWSIKYYKGLG
           +   NAS ++I+ +KGLG
Subjt:  WKESLRGNASGWSIKYYKGLG

AT5G53960.1 ATP binding;DNA binding;DNA topoisomerase (ATP-hydrolyzing)s

3.6e-04

29.66

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Query:  ENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQ
        +++E +L+KLENK R+I  V +  I + +  R  L   L+ +GFTPFP                   +E+ P        S Y+YL       L I+K +
Subjt:  ENLEMELLKLENKVRFILAVVNGEIIVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQ

Query:  ELCNDRDKLKGEVDDLRK
        ELC+ ++ L+  V  L++
Subjt:  ELCNDRDKLKGEVDDLRK

Sequences

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CDS sequence

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ATGGCTGTCGAGAAGAAACGCCCACTGCAGAACAGCAACGTCACCAATGTCGACTCCTATCCGGCAGGTCCAAAGAAAACAATCGAAGAGATGTACCAGAAGAAGTCTCA
GCTCGAGCACATTCTCCTCAGACCCGATACCTATGTCGGATCTATTGAAAAGCACACCCAAAACCTCTGGGTTTACGAGAACGACAGAATGGTTCACCGATCCATCTCCT
ACGTGCCTGGTCTTTACAAGATCTTTGATGAAATTTTGGTCAATGCTGCAGATAATAAGCAGAGAGACCCTTCGATGGATTCAGTCAAGGTAAATATTGACGTCGAACAG
AACTGTATCAGCGTGTTCAACAATGGAGATGGTGTTCCGGTTGAAATTCATCAGGAAGAGAAGGTTTATGTGCCTGAGTTGATCTTTGGACATCTCTTGACTAGTAGTAA
CTATGATGATACTGAAAAGAAAACCACTGGTGGGCGCAATGGCTATGGTGCGAAACTTACCAATATCTTTTCCACTGAATTTGTGATCGAGACGGCTGATGGAAAACGCA
TGAAGAAGTATAAGCAGAAGGAAGTGATTAGCATCTCTTCGACTAATTGTTCGGTGGACTTTGAACTGATTTTATCTTGTATGTTTGATTCATACTCTTTTGCTGAGCCT
CATTTGAAAAATTACTCTTTCGATGTTTTCAATGATAACATGGGGAAAAAATCTGAGCCGATTATAACAAAGTGCAAGGAGGGTGATAATTGGACCAAGGTAACTTTTAA
GCCAGACTTGGCAAAGTTCAACATGACTCATCTTGAAGATGATGTTGTTGCCCTGATGAAAAAGAGAGTATTGGATTTGGCCGGATGTCTTGGTAAAACAGTGAAGGTTG
AGCTGAATGGACAAAGGGTCCCTATTAAATCATTTCAAGATTATGTAGATCTTTACCTCAAATCAGCATCAACATTTCAGACGGAACCTCCGAAAAGGTATCACATTAAG
CCTAACGAGAGATGGGAAATTGTGGTGACCTTAAGTGAGGGCCAGTTCCAGCAGGTCAGCTTTGTGAACGGGATTTCAACTATTAAGGGTGGGACTCATGTTGATTACAT
CACTAATCAAATAGCAAATTATGTGATGACTGTTGTAAATAAGAAGAACAAAAATGCTAACGTGAAGGCCCACAATGTGAAGAGTTATTTATGGGTTTTTATCAACGCTC
TCATTGATAATCCATCCTTTGACTCCCAAACTAAGGAAACTTTGACAAAACGTCCAAACAGTTTTGGTTCTGCATGCGAACTTACACCAGAGTTTTTGAAGAATGTGGCC
ACGAAATCTGGAATTATGGACAGCGTTCTCTCATGGGTTAATTTCAAGCAAAGCAAAGACCTGAAGAAAACAGATGGAGCAAAAACAGAAAAGATTAGTGGTATAGAAAA
GTTGGAGGATGCCAATTGCGCTGGAGGGAAGAACTCGGAAAAATGTACCTTAATTTTGACGGAAGGAGATTCAGCTAAGGCCCTTGCAATGGCTGGGCTTGGTGTAGTAG
GACGAGATTTTTATGGTGTATTCCCACTAAGAGGTAAATTGCTCAATGTGAGGGAAGCAAGTAGTAAACAGATCACAGAGAATAAAGAAATTCAATACATCAAGCAAATT
CTTGGACTTCAGCAAGGGAAGGAATACAGCAATGCTAAGGCTTTGAGATATGGTCATTTGATGATTATGACCGATCAGGATCATGATGGTTCACACATTAAAGGACTTTT
GATCAATTTTATTCATTCTTTCTGGCCTTCTCTCCTAAAAGTGCCGTCGTTCTTGGTTGAATTCATAACGCCTATTGTCAAGGCTACTCATAGGAATGGAACTGTTTTGT
CATTCTATACCATGCCCGAGTACGAGTCTTGGAAAGAGAGCTTGAGAGGCAATGCAAGTGGCTGGTCAATCAAGTACTATAAGGGGTTGGGAACAAGCACATCAAAAGAA
GGAAGAGAGTACTTTGAACAGCTGACAAGGCACAAGAAAGATTTTATTTGGCAAGATGATAATGATGGGGAGGCCATTGAGCTTGCTTTCAGTAAGAAGAAGATTGAAGA
TAGAAAGAATTGGCTCCGTCAATTTGAGCCTGGTACCCATCTAGATCAGACAGGAAAATTGATAAAGTACAGTGACTTCGTCAACAAGGAGCTTATATTATTTTCAATGG
CTGATTTACAAAGGTCTATTCCCTCAATGGTTGATGGCCTTAAGCCTGGCCAAAGGAAGATCCTTTTCTGTTCTTTCAAGAGGAACTTTGTCAAAGAAGCAAAGGTTTCT
CAATTTTCCGGTTATGTATCTGAGCACTCTGCATATCATCATGGTGAGCAGAGTCTTGCTAGTACCATCATTGGAATGGCACAGGACTTCGTTGGTAGCAACAACATTAA
TCTTCTTCTACCAAATGGACAGTTTGGCACACGGAACCATGGAGGCAAAGATCATGCAAGTTCTAGGTACATTTACACTAAACTTTCAAATGTCACACGGTTCCTTTTCC
CAAAAGACGACGACAAACTTCTTAACTACTTAAATGAAGACGGCCAGTCGATTGAACCAACCTGGTATATGCCTATCATACCAACTGTTCTTGTCAATGGAAGTGAAGGA
ATTGGAACCGGGTGGAGTTCGTACGTTCCAAATTATAATCCTAGAGACATCATTAGAAACGTAAGACGTATGTTGGATGGTGAAATGATGTTGCCAATGGATCCCTGGTA
TAGAGGTTTTTCAGGAACTATAGAGAAAACTTCCACTAAAGACGGAGGTACTAGTTACACTGTTAGTGGAATTATAGAGGAAGTCAGTGATACGACGTTGAGAATAATTG
AATTGCCAGTCCGCCGATGGACTAATGACTACAAGGACTTTCTGGACTCTGTCACAAGAGTTGCAACAAAGCATGACAAAGATAAAGAAAAAGCAGCGAAGGATCCTTTT
ATTGAGCAAGCTGATCACCACAGCGATGACAAAATTGTTTCCATTGATGTTCACTTAACGGAGGAAAACATGTTATTGGCCATCCAAGAAGGTTTGAAGAAGAAATTCAA
ATTAACTACAACTGTCAGCACTAGCAACATGCACTTGTTTGATGCAAATGGCGTGATTAAGAAATATGACACCCCAGAACAAATTCTTGAGGAATTTTTTCCCCTGAGAC
TTGAATTCTACGAGAAAAGAAAGAGGAATCTTTTGGAAAACCTTGAAATGGAGTTGCTTAAACTGGAAAACAAGGTGAGGTTTATCCTTGCTGTTGTGAATGGAGAGATA
ATAGTAAGCAATAGAAGAAGGGTTGATTTGTTCCATGAGCTTCAAGCGAAAGGCTTTACACCCTTTCCAAAGAAGACTAAATCTGTTGAGCCAGAAGTTGCTGGGGCATC
TAATGAAACAGATGAAGCAGAGGAGAGTCCGGAAACAGTAAAAGGCGAAAGAGTTAGTGATTACGAGTATTTACTAGCCCTGGCAATTGGAACCTTGACCATTGAGAAGG
TTCAGGAGCTATGTAATGATAGAGACAAGTTGAAAGGGGAAGTGGACGATCTGAGGAAGGCAACCCCCAAGTCTTTGTGGCTGAATGACCTTGATGCTCTTGAGAAAGAA
CTTGATGAGATGGATAGAAATGATGCTCAGGCAATGGAGATAAGAAAACAGCAGAGAGAAAAATCAAATAACGATTTAAAGCCAAAAATCTCTAGAAATGCTCCAAAAGC
TCCACGTAACAGTAAGAAAACCATCAATGCAGAAACTGTCACGGAAAGTATGGACACAACATCTAGTTCTACAACGGAAGTTGCAAATAATCCGGTGGTGAAGCCCAAAG
GCAAAGCAGCTCCAAGAAAAGCTCCCGCTAAGAAGGGTAAAGCTGCAGTTCTTGACGACGAGGACGAAGACGAAATCCTCGAGCTTAAAGACCGTCTTGCTGCCTACAAA
ATTGAGTCATCTCCTGAACCATCAGAAGTTTCAGCCATGGAAACTGAAGTGCCGCAAGTACAAGCGGCCAAGAAGAAAGAACCCAGCAAGAGAGCAGCTCCCAAGAAGAA
AACTACTGCAAAGTCTGCTCAGATCTCCATTAGCGAGGACGATGACGACTTGGAAATAAAGGAGGTAGCCCCTCCGGCAGCCAAGAAGGGAGGAGGAAGAGGAGGAGGAA
GAAAGGCGGCTGCTGCAAATGCCAAAACAACCAAGCCCCCTGCTGCAGGAGTGAAGTTGGGACAGAAACTGATAACTCAAATGCTGGAACCAGCAGAGAACTCCGGCATC
TCACCGGAGAAGAAAGTGAGGAAGATAAGAGCATCACCTTTCAATAAGAAAAGTGGCTCTATATTGGGAAGAACAATTGGGGAAGAGGAAGAAGAAGAAGAAGAAGAAGA
AGAAGAAGAAGCTGGAAATGAAGAGAAGTTGATGGGTTCTGCTTCTTCTGAGACCACTGAAGAAGTTGCCGGATTTCGGCCGGCGAGAGGAAGATCACAGAGAGCAAACA
GAACACAGGTGAAATATGTGGTTAGTGATTCAGAGAGTGAGGCAGTTTCTGAGGATTCGGACTTTGATGAAGAAGCCAGCCTTGATGAAGAAGATTGA

mRNA sequence

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Protein sequence

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MAVEKKRPLQNSNVTNVDSYPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDRMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQ
NCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGKRMKKYKQKEVISISSTNCSVDFELILSCMFDSYSFAEP
HLKNYSFDVFNDNMGKKSEPIITKCKEGDNWTKVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPIKSFQDYVDLYLKSASTFQTEPPKRYHIK
PNERWEIVVTLSEGQFQQVSFVNGISTIKGGTHVDYITNQIANYVMTVVNKKNKNANVKAHNVKSYLWVFINALIDNPSFDSQTKETLTKRPNSFGSACELTPEFLKNVA
TKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQI
LGLQQGKEYSNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFITPIVKATHRNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKE
GREYFEQLTRHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFVKEAKVS
QFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEG
IGTGWSSYVPNYNPRDIIRNVRRMLDGEMMLPMDPWYRGFSGTIEKTSTKDGGTSYTVSGIIEEVSDTTLRIIELPVRRWTNDYKDFLDSVTRVATKHDKDKEKAAKDPF
IEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRNLLENLEMELLKLENKVRFILAVVNGEI
IVSNRRRVDLFHELQAKGFTPFPKKTKSVEPEVAGASNETDEAEESPETVKGERVSDYEYLLALAIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDALEKE
LDEMDRNDAQAMEIRKQQREKSNNDLKPKISRNAPKAPRNSKKTINAETVTESMDTTSSSTTEVANNPVVKPKGKAAPRKAPAKKGKAAVLDDEDEDEILELKDRLAAYK
IESSPEPSEVSAMETEVPQVQAAKKKEPSKRAAPKKKTTAKSAQISISEDDDDLEIKEVAPPAAKKGGGRGGGRKAAAANAKTTKPPAAGVKLGQKLITQMLEPAENSGI
SPEKKVRKIRASPFNKKSGSILGRTIGEEEEEEEEEEEEEAGNEEKLMGSASSETTEEVAGFRPARGRSQRANRTQVKYVVSDSESEAVSEDSDFDEEASLDEED

CmUC10G193640 (gene) of Watermelon (USVL531) v1 genome