CuGenDBv2

Gene ID	CmUC10G198150
Organism	Citrullus mucosospermus (Watermelon (USVL531) v1)
Description	DNA topoisomerase
Genome location	CmU531Chr10:30024871..30049394
RNA-Seq Expression	CmUC10G198150
Synteny	CmUC10G198150
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0005634 - nucleus (cellular component) GO:0005694 - chromosome (cellular component) GO:0003677 - DNA binding (molecular function) GO:0008270 - zinc ion binding (molecular function) GO:0003917 - DNA topoisomerase type I activity (molecular function)
InterPro domains	IPR006171 - TOPRIM domain IPR036875 - Zinc finger, CCHC-type superfamily IPR034144 - DNA topoisomerase 3-like, TOPRIM domain IPR023406 - DNA topoisomerase, type IA, active site IPR023405 - DNA topoisomerase, type IA, core domain IPR013826 - DNA topoisomerase, type IA, central region, subdomain 3 IPR013824 - DNA topoisomerase, type IA, central region, subdomain 1 IPR013498 - DNA topoisomerase, type IA, zn finger IPR013497 - DNA topoisomerase, type IA, central IPR010666 - Zinc finger, GRF-type IPR003602 - DNA topoisomerase, type IA, DNA-binding domain IPR003601 - DNA topoisomerase, type IA, domain 2 IPR001878 - Zinc finger, CCHC-type IPR000380 - DNA topoisomerase, type IA

Homology

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GenBank top hits

e value

%identity

Alignment

XP_008443145.1 PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Cucumis melo]

0.0e+00

82.52

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Query:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK
        MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVR+GRSRYNKIFEFNYAIRGQSCNM+VTSVTGHLMEL FEERYRKW+SCDPVQLF+APV KFVPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        +DIKRTLEQEARR QWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQT+LL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY
        KDAFNIDSV DD+NIVLSYGPCQFPTLGFVVERYWEIQ+HEPEEFWTINCSHNSDDGISTF WTRGNLFDYTCAV+FYEMCVQESTATVVNVRRQETLKY
Subjt:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH                        GLWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHH+LYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYV+GQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPT+LGEALVMGYDDMGYNLWKPHLRAIME EMKAVSEGTKRKDEVLA+CLQQMK+C
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC

Query:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ
        FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQ CGLCQ+SDMVLKRNRDGNYMVGC AFPQCRNVVWLPGSIAEA VTSDRC LCTPGPVYLIQ
Subjt:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ

Query:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN
        FKFRQLEIPPNYNANHLGC+GGCDDILRQLTEICGTGSRVS                                    G+    +   + NP   V  F  
Subjt:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN

Query:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQR---ESSVSCSNCGTPCVLRTANTTNNRGRKFYKCQSQECNFFVWEDNVDNGNGGN
        +              HS+               S SV   + R R   ESSVSCS+CGTPCVLRTANTTNNRGRKFYKCQSQECNFFVWEDNVDN NGGN
Subjt:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQR---ESSVSCSNCGTPCVLRTANTTNNRGRKFYKCQSQECNFFVWEDNVDNGNGGN

Query:  SVPWSNIRSSGTTASNLNPSRNTGRGQG----------CGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG
        S   SN+RSSG+  SN NP +NTGRG+G           G+GQIA TFVSATGEPISDRRCFVCGDPSHFANVCPNRG
Subjt:  SVPWSNIRSSGTTASNLNPSRNTGRGQG----------CGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG

XP_011652135.2 DNA topoisomerase 3-alpha isoform X1 [Cucumis sativus]

0.0e+00

82.5

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Query:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK
        MSGGR ITVLNVAEKPSVAKSVATILSRNQGLRVR+GRSRYNKIFEFNYAIRGQSCNM+VTSVTGHLMEL FEERYRKWHSCDPVQLF+APV KFVPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        +DIKRTLEQE+RR QWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIH+AVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQT+LL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY
        KDAFNIDSV DD+NIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTF WTRGNLFDYTCAV+FYEMCVQESTATVVNVRRQETLKY
Subjt:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH                         LWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHH+LYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYV+GQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLG+ALVMGYDDMGYNLWKP+LRAIME EMKAVSEGTKRKDEVLA+CLQQMK+C
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC

Query:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ
        FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQ CGLCQDSDMVLKRNRDGNYMVGC AFPQCRNVVWLPGSIAEA VTSDRC LCTPGPVYLIQ
Subjt:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ

Query:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN
        FKFRQLEIPPNYNANHLGC+GGCDDILRQLTEICGTGSRVS                                    G+    +   + NP   V  F  
Subjt:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN

Query:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQRESSVSCSNCGTPCVLRTANTTNNRGRKFYKCQSQECNFFVWEDNVDNGNGGNSVP
        +              HS+           +   S S QR   +  ESSVSCS+CG+PCVLRTANT NNRGRKFYKCQSQECNFFVWEDNVDNGNGGNSV 
Subjt:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQRESSVSCSNCGTPCVLRTANTTNNRGRKFYKCQSQECNFFVWEDNVDNGNGGNSVP

Query:  WSNIRSSGTTASNLNPSRNTGRGQGCGR------------GQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG
         SN+RSSG+  SNLNP +NTGRG+G GR            GQIA TFVSATGEPISDRRCFVCGDPSHFANVCPNRG
Subjt:  WSNIRSSGTTASNLNPSRNTGRGQGCGR------------GQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG

XP_022982837.1 DNA topoisomerase 3-alpha isoform X1 [Cucurbita maxima]

0.0e+00

80.6

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Query:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK
        M+GGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPV+LFNAPVRK VPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCT VN HLNIKRAHFSALIERDIHEAVQNLVQPNK+FADAVDARQEIDLRIGASFTRFQTMLL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY
        KDAFNIDSV DD+N+VLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNS DGISTF WTRGNLFDYTCAV+ YEMCV+ESTATVVNVRRQETLKY
Subjt:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH                        GLWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHH+LYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTY +GQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGY LWKPHLRA+ME EMKAVSEG KRKDEVLATCLQQMKSC
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC

Query:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ
        FLDAR NKQKL EAMEVFFERSNGSGGDEN AVGEVVQRC LCQDSDMVLKRNRDGNYMVGC  FPQCRNVVWLPGSIAEAAVTS+RCN CTPGPVYLIQ
Subjt:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ

Query:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN
        FKFRQLEIPPNYN NHLGCIGGCDDILRQLTEICGTGSR+S                                                           
Subjt:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN

Query:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQR-------------------------------ESSVSCSNCGTPCVLRTANTTNNR
                                  ARGRGTSSSSVQR NT Q                                ESS SCSNCGTPCVLRTANTTNNR
Subjt:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQR-------------------------------ESSVSCSNCGTPCVLRTANTTNNR

Query:  GRKFYKCQSQECNFFVWEDNVDNGNGGNSVPWSNIRSSGTTASNLNPSRNTGR----GQGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG
        GRKFYKCQSQECNFF WED+VD+ NGGNS   SNIRSS + ASN NP RNTGR    GQG G+GQIA TFVSATGEPISDRRCFVCGDPSHFANVCPNRG
Subjt:  GRKFYKCQSQECNFFVWEDNVDNGNGGNSVPWSNIRSSGTTASNLNPSRNTGR----GQGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG

XP_023526238.1 DNA topoisomerase 3-alpha isoform X1 [Cucurbita pepo subsp. pepo]

0.0e+00

80.12

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Query:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK
        M+G RPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPV+LFNAPVRK VPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCT VN HLNIKRAHFSALIERDIHEAVQNLVQPNK+FADAVDARQEIDLRIGASFTRFQTMLL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY
        KDAFNIDSV DD+N+VLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNS DGISTF WTRGNLFDYTCAV+ YEMCV+ESTATVVNV+RQETLKY
Subjt:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH                        GLWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHH+LYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTY +GQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGY LWKPHLRA+ME EMKAVSEG KRKDEVLATCLQQMKSC
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC

Query:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ
        FLDAR NKQKL EAMEVFFERSNGSGGDEN AVGEVVQRC LCQDSDMVLKRNRDGNYMVGC  FPQCRNVVWLPGSIAEAAVTS+RCN CTPGPVYLIQ
Subjt:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ

Query:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN
        FKFRQLEIPPNYN NHLGCIGGCDDILRQLTEICGTGSR+S                                                           
Subjt:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN

Query:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNT----------------------------RQR---ESSVSCSNCGTPCVLRTANTTNNR
                                  ARGRGTSSSSVQR NT                            R+R   ESS SCSNCGTPCVLRTANTTNNR
Subjt:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNT----------------------------RQR---ESSVSCSNCGTPCVLRTANTTNNR

Query:  GRKFYKCQSQECNFFVWEDNVDNGNGGNSVPWSNIRSSGTTASNLNPSRNTGR----------GQGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFAN
        GRKFYKCQSQECNFF WED+VD+ NGGNS   SNIRSSG+ ASN NP RNTGR          GQG G+GQIA TFVSATGEPISDRRCFVCGDPSHFAN
Subjt:  GRKFYKCQSQECNFFVWEDNVDNGNGGNSVPWSNIRSSGTTASNLNPSRNTGR----------GQGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFAN

Query:  VCPNRG
        VCPNRG
Subjt:  VCPNRG

XP_038904101.1 DNA topoisomerase 3-alpha isoform X1 [Benincasa hispida]

0.0e+00

82.23

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Query:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK
        MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVR+GRSRYNKIFEFNYAIRGQSCNM+VTSVTGHLMELEFEERYRKWHSCDPVQLF+APVRK VPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        MDIKRTLEQEARRCQWL+LWLDCDREGENIAFEVVEVCTAVN HLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY
        KDAFNIDSV DD+NIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNS DGISTF WTRGNLFDYTCAV+FYEMCVQE TATVVNVRRQETLKY
Subjt:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH                        GLWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHH+LYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYV+GQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIME EMKAVSEGTKRKDEVLATCLQQMKSC
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC

Query:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ
        FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDS+MVLKRNRDGNYMVGC AFPQCRNVVWLPGSIAEAAVTSD CNLCTPGPVYLIQ
Subjt:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ

Query:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN
        FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVS                                                           
Subjt:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN

Query:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQR-------------------------------ESSVSCSNCGTPCVLRTANTTNNR
                                  ARGRGTSSSSVQRDNTRQ                                E SVSCSNCGTPCVLRTANTTNNR
Subjt:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQR-------------------------------ESSVSCSNCGTPCVLRTANTTNNR

Query:  GRKFYKCQSQECNFFVWEDNVDNGNGGNSVPWSNIRSSGTTASNLNPSRNTGRGQGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG
        GRKFYKCQSQECNFFVWEDNVDN NGGNS   SNIR+SG+ A N NP RNTGRG+G G  +IA TFVSATGEPISDRRCFVCGD SHFANVCPNRG
Subjt:  GRKFYKCQSQECNFFVWEDNVDNGNGGNSVPWSNIRSSGTTASNLNPSRNTGRGQGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LBG7 DNA topoisomerase

0.0e+00

82.5

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Query:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK
        MSGGR ITVLNVAEKPSVAKSVATILSRNQGLRVR+GRSRYNKIFEFNYAIRGQSCNM+VTSVTGHLMEL FEERYRKWHSCDPVQLF+APV KFVPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        +DIKRTLEQE+RR QWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIH+AVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQT+LL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY
        KDAFNIDSV DD+NIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTF WTRGNLFDYTCAV+FYEMCVQESTATVVNVRRQETLKY
Subjt:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH                         LWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHH+LYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYV+GQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKP+LRAIME EMKAVSEGTKRKDEVLA+CLQQMK+C
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC

Query:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ
        FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQ CGLCQDSDMVLKRNRDGNYMVGC  FPQCRNVVWLPGSIAEA VTSDRC LCTPGPVYLIQ
Subjt:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ

Query:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN
        FKFRQLEIPPNYNANHLGC+GGCDDILRQLTEICGTGSRVS                                    G+    +   + NP   V  F  
Subjt:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN

Query:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQRESSVSCSNCGTPCVLRTANTTNNRGRKFYKCQSQECNFFVWEDNVDNGNGGNSVP
        +              HS+           +   S S QR   +  ESSVSCS+CG+PCVLRTANT NNRGRKFYKCQSQECNFFVWEDNVDNGNGGNSV 
Subjt:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQRESSVSCSNCGTPCVLRTANTTNNRGRKFYKCQSQECNFFVWEDNVDNGNGGNSVP

Query:  WSNIRSSGTTASNLNPSRNTGRGQGCGR------------GQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG
         SN+RSSG+  SNLNP +NTGRG+G GR            GQIA TFVSATGEPISDRRCFVCGDPSHFANVCPNRG
Subjt:  WSNIRSSGTTASNLNPSRNTGRGQGCGR------------GQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG

A0A1S3B7B9 DNA topoisomerase

0.0e+00

82.52

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Query:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK
        MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVR+GRSRYNKIFEFNYAIRGQSCNM+VTSVTGHLMEL FEERYRKW+SCDPVQLF+APV KFVPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        +DIKRTLEQEARR QWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQT+LL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY
        KDAFNIDSV DD+NIVLSYGPCQFPTLGFVVERYWEIQ+HEPEEFWTINCSHNSDDGISTF WTRGNLFDYTCAV+FYEMCVQESTATVVNVRRQETLKY
Subjt:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH                        GLWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHH+LYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYV+GQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPT+LGEALVMGYDDMGYNLWKPHLRAIME EMKAVSEGTKRKDEVLA+CLQQMK+C
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC

Query:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ
        FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQ CGLCQ+SDMVLKRNRDGNYMVGC AFPQCRNVVWLPGSIAEA VTSDRC LCTPGPVYLIQ
Subjt:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ

Query:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN
        FKFRQLEIPPNYNANHLGC+GGCDDILRQLTEICGTGSRVS                                    G+    +   + NP   V  F  
Subjt:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN

Query:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQR---ESSVSCSNCGTPCVLRTANTTNNRGRKFYKCQSQECNFFVWEDNVDNGNGGN
        +              HS+               S SV   + R R   ESSVSCS+CGTPCVLRTANTTNNRGRKFYKCQSQECNFFVWEDNVDN NGGN
Subjt:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQR---ESSVSCSNCGTPCVLRTANTTNNRGRKFYKCQSQECNFFVWEDNVDNGNGGN

Query:  SVPWSNIRSSGTTASNLNPSRNTGRGQG----------CGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG
        S   SN+RSSG+  SN NP +NTGRG+G           G+GQIA TFVSATGEPISDRRCFVCGDPSHFANVCPNRG
Subjt:  SVPWSNIRSSGTTASNLNPSRNTGRGQG----------CGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG

A0A5A7TKA3 DNA topoisomerase

0.0e+00

80.18

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Query:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK
        MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVR+GRSRYNKIFEFNYAIRGQSCNM+VTSVTGHLMEL FEERYRKW+SCDPVQLF+APV KFVPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDAR-------------------
        +DIKRTLEQEARR QWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDAR                   
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDAR-------------------

Query:  -------QEIDLRIGASFTRFQTMLLKDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCA
               QEIDLRIGASFTRFQT+LLKDAFNIDSV DD+NIVLSYGPCQFPTLGFVVERYWEIQ+HEPEEFWTINCSHNSDDGISTF WTRGNLFDYTCA
Subjt:  -------QEIDLRIGASFTRFQTMLLKDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCA

Query:  VIFYEMCVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-------------------
        V+FYEMCVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH                   
Subjt:  VIFYEMCVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-------------------

Query:  ----VGLWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGST
             GLWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHH+LYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGST
Subjt:  ----VGLWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGST

Query:  IPTYVTGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMEL
        IPTYV+GQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPT+LGEALVMGYDDMGYNLWKPHLRAIME 
Subjt:  IPTYVTGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMEL

Query:  EMKAVSEGTKRKDEVLATCLQQMKSCFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWL
        EMKAVSEGTKRKDEVLA+CLQQMK+CFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQ CGLCQ+SDMVLKRNRDGNYMVGC AFPQCRNVVWL
Subjt:  EMKAVSEGTKRKDEVLATCLQQMKSCFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWL

Query:  PGSIAEAAVTSDRCNLCTPGPVYLIQFKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHN
        PGSIAEA VTSDRC LCTPGPVYLIQFKFRQLEIPPNYNANHLGC+GGCDDILRQLTEICGTGSRVSG                                
Subjt:  PGSIAEAAVTSDRCNLCTPGPVYLIQFKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHN

Query:  LEEGKLLHMTQEIKTNPFADVYDFSNKGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQR---ESSVSCSNCGTPCVLRTANTTNNRGR
           G+    +   + NP   V  F  +              HS+               S SV   + R R   ESSVSCS+CGTPCVLRTANTTNNRGR
Subjt:  LEEGKLLHMTQEIKTNPFADVYDFSNKGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQR---ESSVSCSNCGTPCVLRTANTTNNRGR

Query:  KFYKCQSQECNFFVWEDNVDNGNGGNSVPWSNIRSSGTTASNLNPSRNTGRGQGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG
        KFYKCQSQECNFFVWEDNVDN NGGNS   SN+RSSG+  SN NP+                TFVSATGEPISDRRCFVCGDPSHFANVCPNRG
Subjt:  KFYKCQSQECNFFVWEDNVDNGNGGNSVPWSNIRSSGTTASNLNPSRNTGRGQGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG

A0A6J1F0T9 DNA topoisomerase

0.0e+00

80.3

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Query:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK
        M+GGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPV+LFNAPVRK VPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        MDIKRTLEQEA RCQWLVLWLDCDREGENIAFEVVEVCT VN HLNIKRAHFSALIERDIHEAVQNLVQPNK++ADAVDARQEIDLRIGASFTRFQTMLL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY
        KDAFNIDSV DD+N+VLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNS DGISTF WTRGNLFDYTCAV+ YEMCV+ESTATVVNV+RQETLKY
Subjt:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH                        GLWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHH+LYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTY +GQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGY LWKPHLRA+ME EMKAVSEG KRKDEVLATCLQQMKSC
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC

Query:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ
        FLDAR NKQKL EAMEVFFERSNGSGGDEN AVGEVVQRC LCQDSDMVLKRNRDGNYMVGC  FPQCRNVVWLPGSIAEAAVTS+RCN CTPGPVYLIQ
Subjt:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ

Query:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN
        FKFRQLEIPPNYN NHLGCIGGCDDILRQLTEICGTGSR+S                                                           
Subjt:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN

Query:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQR-------------------------------ESSVSCSNCGTPCVLRTANTTNNR
                                  ARGRGTSSSSVQR NT Q                                ESS SCSNCGTPCVLRTANTTNNR
Subjt:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQR-------------------------------ESSVSCSNCGTPCVLRTANTTNNR

Query:  GRKFYKCQSQECNFFVWEDNVDNGNGGNSVPWSNIRSSGTTASNLNPSRNT----GRGQGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG
        GRKFYKCQSQECNFF WED+VD+ NGGNS   SNIRSSG+ ASN NP RNT    GRGQG G+GQIA TFVSA GEPISDRRCFVCGDPSHFANVCPNRG
Subjt:  GRKFYKCQSQECNFFVWEDNVDNGNGGNSVPWSNIRSSGTTASNLNPSRNT----GRGQGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG

A0A6J1IXM8 DNA topoisomerase

0.0e+00

80.6

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Query:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK
        M+GGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPV+LFNAPVRK VPEDK
Subjt:  MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDK

Query:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL
        MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCT VN HLNIKRAHFSALIERDIHEAVQNLVQPNK+FADAVDARQEIDLRIGASFTRFQTMLL
Subjt:  MDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLL

Query:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY
        KDAFNIDSV DD+N+VLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNS DGISTF WTRGNLFDYTCAV+ YEMCV+ESTATVVNVRRQETLKY
Subjt:  KDAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKY

Query:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP
        PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH                        GLWRNPSGGGHDDKAHPPIHP
Subjt:  PPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHP

Query:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP
        TKFSAGERGWSQDHH+LYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTY +GQQFVPTTLTLDSGVTRPPP
Subjt:  TKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPP

Query:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC
        LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGY LWKPHLRA+ME EMKAVSEG KRKDEVLATCLQQMKSC
Subjt:  LLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSC

Query:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ
        FLDAR NKQKL EAMEVFFERSNGSGGDEN AVGEVVQRC LCQDSDMVLKRNRDGNYMVGC  FPQCRNVVWLPGSIAEAAVTS+RCN CTPGPVYLIQ
Subjt:  FLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQ

Query:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN
        FKFRQLEIPPNYN NHLGCIGGCDDILRQLTEICGTGSR+S                                                           
Subjt:  FKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSN

Query:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQR-------------------------------ESSVSCSNCGTPCVLRTANTTNNR
                                  ARGRGTSSSSVQR NT Q                                ESS SCSNCGTPCVLRTANTTNNR
Subjt:  KGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQR-------------------------------ESSVSCSNCGTPCVLRTANTTNNR

Query:  GRKFYKCQSQECNFFVWEDNVDNGNGGNSVPWSNIRSSGTTASNLNPSRNTGR----GQGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG
        GRKFYKCQSQECNFF WED+VD+ NGGNS   SNIRSS + ASN NP RNTGR    GQG G+GQIA TFVSATGEPISDRRCFVCGDPSHFANVCPNRG
Subjt:  GRKFYKCQSQECNFFVWEDNVDNGNGGNSVPWSNIRSSGTTASNLNPSRNTGR----GQGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG

SwissProt top hits

e value

%identity

Alignment

C7J0A2 DNA topoisomerase 3-alpha

0.0e+00

62.78

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Query:  GGRPITVLNVAEKPSVAKSVATILSR-NQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDKM
        GG  I VLNVAEKPSVAKSVA ILSR + G+R REGRSRYN++FEF+Y+I G++C+MLVTSVTGHLMELEF++R+R+WHSCDP  LF+APVRK VP+DK 
Subjt:  GGRPITVLNVAEKPSVAKSVATILSR-NQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDKM

Query:  DIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLK
        DIKRTLE+EAR+CQWLVLWLDCDREGENIA+EV+++C   N  LNI RA FSALI+R+IHEAVQ+L +PNK FADAVDARQEIDLRIGASFTRFQTMLLK
Subjt:  DIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLK

Query:  DAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKYP
        DAF +D   DD+NI+LSYGPCQFPTLGF+VER+WEIQ+HEPEEFWTINCSH SD+G ++F W RG+LFDY+ AV+ YEMCV+E  ATV NVR QE LKYP
Subjt:  DAFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKYP

Query:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHPT
        P+PL+TIEL+KRASRYFRMSSEHTMKVAE+LYQAGFISYPRTETD FS  TDLH                         LWRNPS GGHDDKAHPPIHPT
Subjt:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLH-----------------------VGLWRNPSGGGHDDKAHPPIHPT

Query:  KFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPPL
        KFSAGE  W+ +H KLYELVVRHFLAC SQPAVGA TTVEIDIAGE F+ SGR++LA+NYLDVYRF+SWGG+ +PTY+ GQQFVPTTLTLDSG+TRPPPL
Subjt:  KFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPPL

Query:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSCF
        L+EADLL CMDK GIGTDATMHDHIKKLLDR YATKDANTRF+PTNLGEALVMGYD+MGY LWKP+LR++ME +MK+VS GTK K EVL  CLQQMK+CF
Subjt:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSCF

Query:  LDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQF
        LDAR NK KL +AM  FF RS+    +   ++ E V+ C  C +S+M LK+   G +MVGC  FPQCRNVVWLP S++ AAVT   C  C PGPVY IQF
Subjt:  LDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQF

Query:  KFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSNK
        KFR+ +IPPN++ +HLGCIGGCDDIL++L E+   GS         +                   + Q    + +G      Q++ T+ F     F+N 
Subjt:  KFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSNK

Query:  GTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQRESSVSCSNCGTPCVLRTANTTNNRGRKFYKCQSQECNFFVWEDNVDN----GNGGN
        G  P+  P      H+          +  G +S  VQ            C++C  PCVLRTANT  NRGRKFYKCQ+  C FF WED+V+N    G GG 
Subjt:  GTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQRESSVSCSNCGTPCVLRTANTTNNRGRKFYKCQSQECNFFVWEDNVDN----GNGGN

Query:  SVPW-SNIRSSGTTASNLNPSRNTGRG-QGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG
             S+ R S  +AS        GRG +G GR      FV+ATGEP+    CF+CGDP+HFANVCPN G
Subjt:  SVPW-SNIRSSGTTASNLNPSRNTGRG-QGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRG

O70157 DNA topoisomerase 3-alpha

8.9e-192

39.67

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Query:  VLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDKMDIKRTLE
        VL VAEK   AK +A +LS N  +R +EG S++NKI+EF+Y + GQ+  M++TSV+GHL+  +F+ ++RKW SC+P+ LF A + K+ PE+ +DIK+TLE
Subjt:  VLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDKMDIKRTLE

Query:  QEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNIDS
        +E   CQ LV+W DCDREGENI FE++ VC AV  +L + RA FS +    +  A +NL +P++  +DAVD RQE+DLRIGA+FTRFQT+ L+  F  + 
Subjt:  QEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNIDS

Query:  VADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKYPPHPLNTI
        +A+    ++SYG CQFPTLGFVVER+  IQ+  PE F  I  +H+  DG   F W R  LF++T  ++ Y++C+++  ATVV VR +   K+ P  L+T+
Subjt:  VADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKYPPHPLNTI

Query:  ELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCF-----------SQRTDLHVGLWR---------NPSGGGHDDKAHPPIHPTKFSAGERGWS
        ELEK ASR  R++++ TM++AE LY  G+ISYPRTET+ F            Q  D H G +           P  G   D+AHPPIHPTK+++G +G  
Subjt:  ELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCF-----------SQRTDLHVGLWR---------NPSGGGHDDKAHPPIHPTKFSAGERGWS

Query:  QDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPPLLSEADLLSCM
         D  +LYE +VRHFLAC SQ A G  TTVEIDIA E F   G +ILARNYLDVY ++ W    +P Y  G  F P+T+ +  G T PP LL+EADL++ M
Subjt:  QDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPPLLSEADLLSCM

Query:  DKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSCFLDARVNKQKL
        +K GIGTDAT  +HI+ +  R Y    ++ RF P +LG  LV GYD MGY + KP LRA +E ++K + EG K K +VL   +Q+ K  F++A    +KL
Subjt:  DKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSCFLDARVNKQKL

Query:  LEAMEVFF-ERSNGSGGDE-NRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQFKFRQLEIP
         EA+  +  ER+  +  +E   A+ E V++C  C + DMVLK  + G + + C  FP+CR+ VW P S+ EA+  +  C++C P PVY ++ KF++  +P
Subjt:  LEAMEVFF-ERSNGSGGDE-NRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQFKFRQLEIP

Query:  PNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLH---MTQEIKTNPFADVYDFSNKGTIPI
        P      +GCIGGCD+ L+                          E+F   F   L    Q + +L+  + L+    +Q   + P  + +   +K     
Subjt:  PNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLH---MTQEIKTNPFADVYDFSNKGTIPI

Query:  TFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQRESSVSCSNCGTPCVLRTANTTN-NRGRKFYKCQSQECNFFVWEDNVDNGNGG-----NSVP
          PP                               T    +SV+C NCG   VL T      N+GR FYKC + +CNFF+W D+  +  GG     +  P
Subjt:  TFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQRESSVSCSNCGTPCVLRTANTTN-NRGRKFYKCQSQECNFFVWEDNVDNGNGG-----NSVP

Query:  WSNIRSSGTTASNLNPSRNTGR----GQGCGRGQIATTFVSATGEPISDRRCFVCGDP
         S++    +  S+++   + G     G  C  GQ A T       P   R+   C  P
Subjt:  WSNIRSSGTTASNLNPSRNTGR----GQGCGRGQIATTFVSATGEPISDRRCFVCGDP

Q13472 DNA topoisomerase 3-alpha

4.3e-194

39.83

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Query:  VLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDKMDIKRTLE
        VL VAEK   AK +A +LS N  +R REG S++NKI+EF+Y + GQ+  M++TSV+GHL+  +F+ ++RKW SC+P+ LF A + K+ PE+ +DIK+TLE
Subjt:  VLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDKMDIKRTLE

Query:  QEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNIDS
        +E R+CQ LV+W DCDREGENI FE++ VC AV  +L + RA FS +    +  A +NL +P++  +DAVD RQE+DLRIGA+FTRFQT+ L+  F  + 
Subjt:  QEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNIDS

Query:  VADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKYPPHPLNTI
        +A+    ++SYG CQFPTLGFVVER+  IQ+  PE F  I  +H+  DGI  F W R  LF++T  ++ Y++CV++  ATVV VR +   K+ P  L+T+
Subjt:  VADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKYPPHPLNTI

Query:  ELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHVGL--------W------------RNPSGGGHDDKAHPPIHPTKFSAGERGWS
        ELEK ASR  R++++ TM++AE LY  G+ISYPRTET+ F +  +L V +        W              P  G   D+AHPPIHPTK++   +G  
Subjt:  ELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHVGL--------W------------RNPSGGGHDDKAHPPIHPTKFSAGERGWS

Query:  QDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPPLLSEADLLSCM
         D  +LYE +VRHFLAC SQ A G  TTVEIDIA E F   G MILARNYLDVY ++ W    +P Y  G  F P+T+ +  G T PP LL+EADL++ M
Subjt:  QDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPPLLSEADLLSCM

Query:  DKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSCFLDARVNKQKL
        +K GIGTDAT  +HI+ +  R Y     + RF P +LG  LV GYD MGY + KP LRA +E ++K + +G K K  VL   +Q+ K  F++A    +KL
Subjt:  DKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSCFLDARVNKQKL

Query:  LEAMEVFFERSNGSGGDEN--RAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQFKFRQLEIP
         EA+  +F         E+   A+ E +++C  C + DMVLK  ++G + + C  FP+CR+ VWLP S+ EA+  S  C +C P PVY ++ KF++  +P
Subjt:  LEAMEVFFERSNGSGGDEN--RAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQFKFRQLEIP

Query:  PNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSNKGTIPITFP
        P      + CIGGCDD LR++ ++  +G                                Q +  L+  + L+     +    AD     +   +  T P
Subjt:  PNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSNKGTIPITFP

Query:  PILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQRESSVSCSNCGTPCVLRTANTTN-NRGRKFYKCQSQECNFFVWEDNVDNGNGG------------
        P      SN                             SV+C NCG   VL T      NRGR+F+KC    CNFF+W D+ + G GG            
Subjt:  PILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQRESSVSCSNCGTPCVLRTANTTN-NRGRKFYKCQSQECNFFVWEDNVDNGNGG------------

Query:  -NSVPWSNIRSSGTTASNLNPSRNTGRGQGCGRGQIATTFVSATGEPISDRRCFVCGDP
            P   I   G      NP   +G G  C   Q + T       P   R+   C  P
Subjt:  -NSVPWSNIRSSGTTASNLNPSRNTGRGQGCGRGQIATTFVSATGEPISDRRCFVCGDP

Q8T2T7 DNA topoisomerase 3

4.5e-159

44.48

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Query:  VLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRG-QSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDKMDIKRTL
        +LNVAEKPS AK +A ILS N+   VREG S+YNK+++F Y I     C M  TSVTGHLME++  E+++ W SCDP+QLF+AP+RK VP DK  +K+TL
Subjt:  VLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRG-QSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDKMDIKRTL

Query:  EQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNID
        E+E ++   L+LWLDCDREGENIAFEV+EVC          RAHFSA+I R+I  A +NL +PN+  + AVD R EIDLRIGA+FTRFQT+ LK  F I 
Subjt:  EQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNID

Query:  SVADDK---------NI------------VLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGIS------TFCWTRGNLFDYTCAVIFYEM
        S +D++         NI            ++SYGPCQFPTLGFVVERY+ I + +PE+FW ++  H   D  S      TF W R  LFDYT A I YE 
Subjt:  SVADDK---------NI------------VLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGIS------TFCWTRGNLFDYTCAVIFYEM

Query:  CVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHVGLWRN-------------------
        C+  + ATVV+V  +E+ +Y P PL TIEL+K AS+  R+SS  TM+ AE+LY  G ISYPRTETD F   TDL  GL  N                   
Subjt:  CVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHVGLWRN-------------------

Query:  ---PSGGGHDDKAHPPIHPTKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTG
           P  G ++D +HPPIHPT  + G  G   +  K+Y+ + R FLAC S+ +V A TTV IDI GE FS +G M+L   YL+VY F+      IPTY  G
Subjt:  ---PSGGGHDDKAHPPIHPTKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTG

Query:  QQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSE
        ++F P  + L  G T  P  ++EA+LL+ MD   IGTDATM  HI+ + DRFY  K+ + +F P+NLG +LV  Y+ MG+   KP+LRA +E ++  +S 
Subjt:  QQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSE

Query:  GTKRKDEVLATCLQQMKSCFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLP--GSIA
        G K K EVL + +++ K  +  A  N      +   ++E ++  GG E R +     RCG C +  M  K +++          PQC +   LP  G I+
Subjt:  GTKRKDEVLATCLQQMKSCFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLP--GSIA

Query:  EAAVT---SDRCNLC
        +   +      C +C
Subjt:  EAAVT---SDRCNLC

Q9LVP1 DNA topoisomerase 3-alpha

0.0e+00

63.87

Show/hide

Query:  GGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDKMD
        GG P+TVLNVAEKPSVAKSVA ILSR    R REGRSRYNKIFEF+YAI GQ C ML+TSV GHLMELEF +RYRKWHSCDP  L+ APV K VPEDK D
Subjt:  GGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDKMD

Query:  IKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKD
        IK+TLE+EAR+  WLVLWLDCDREGENIAFEVV+VC AV H+L I+RAHFSALI+RDIHEAVQNL  PN+ FA+AVDARQEIDLRIGASFTRFQTMLL+D
Subjt:  IKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKD

Query:  AFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNV-RRQETLKYP
         F IDS  ++++ V+SYGPCQFPTLGF+VERYWEIQ+HEPEEFWTINCSH S++G++TF W RG+LFDY  AVI YEMCV+E TATV+NV   +E  KYP
Subjt:  AFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNV-RRQETLKYP

Query:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHV-----------------------GLWRNPSGGGHDDKAHPPIHPT
        P+PLNTIELEKRASRYFR+SSEHTMKVAE+LYQAGFISYPRTETD FS RTDL                         GLWRNP+ GGHDDKAHPPIHPT
Subjt:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHV-----------------------GLWRNPSGGGHDDKAHPPIHPT

Query:  KFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPPL
        KFS+GE  WS+DH  +YELVVRH+LACVSQPAV A TTVEIDIAGE FS SGR ILA+NYL+VYRFESWGGS IP Y  GQQF+PTTLTLD+ VTRPPPL
Subjt:  KFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPPL

Query:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSCF
        L EADLLSCMDK GIGTDATMHDHIKKLLDR YATKDANTRF+PTNLGEALVMGYDDMGY LWKP+LRA+ME +M  VS G K K EVL TCLQQMK+CF
Subjt:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSCF

Query:  LDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQF
        LDARV K KLLEAM +FFERSN +   E++  GEVV+RC LC +SDM L++NRDGN+MVGC  +PQCRN VWLPG   EA+VT++ C  C PGPVY I F
Subjt:  LDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQF

Query:  KFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSNK
        KFRQ+ IPP ++ NHLGC+GGCDDIL+QL +ICGTGSR                                                           S  
Subjt:  KFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSNK

Query:  GTIPITFPPILLFAHSNYVLKLCFAARGRGTSS------------SSVQRDNTRQRESSVSCSNCGTPCVLRTANTTNNRGRKFYKCQSQECNFFVWEDN
           P T P   +   +     +C   + RG +S            S     N R  ES+VSC+ CG+ CVLRTANT  NRGR+F+ C +Q C+FF WED+
Subjt:  GTIPITFPPILLFAHSNYVLKLCFAARGRGTSS------------SSVQRDNTRQRESSVSCSNCGTPCVLRTANTTNNRGRKFYKCQSQECNFFVWEDN

Query:  VDNGNGGNSVPWSNIRSSGTTASNLNPSRNTGRGQGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRGN
        ++N + GN+   SN   SG   S        G     GR    T+FVSATGEP+S  RCF CGDPSHFAN CPNR N
Subjt:  VDNGNGGNSVPWSNIRSSGTTASNLNPSRNTGRGQGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRGN

Arabidopsis top hits

e value

%identity

Alignment

AT2G32000.1 DNA topoisomerase, type IA, core

2.2e-105

35.61

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Query:  ITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDKMDIKRT
        + VL VAEKPS+A S+A++LS  Q +  R G +   ++ EF+   RG   +  VTSV GH+  ++F E+Y+ W + DP  LF+AP+ K     K  I R 
Subjt:  ITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDKMDIKRT

Query:  LEQEARRCQWLVLWLDCDREGENIAFEVVEVC--TAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAF
        L  EAR C ++VLWLDCDREGENI FEV+E       +    + RA FS++ E+DI +A+ NLV+PN+  A AVDARQEIDL++G +F+RFQT   +  +
Subjt:  LEQEARRCQWLVLWLDCDREGENIAFEVVEVC--TAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAF

Query:  -NIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKYPPH
         N+D        V+SYGPCQ PTLGF V+RY  I + +PE+FW +      D       W R  LFD   A +F ++ V+  TA V++V  ++ +K  P 
Subjt:  -NIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKYPPH

Query:  PLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQR---TDLHVGLWRNPSGGGH----------------DDKAHPPIHPTKFSAGE
         LNT+ L K AS       +  M +AE LY  GFISYPRTE+  +      TD       NP  GG+                D   HPPI P + +A E
Subjt:  PLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQR---TDLHVGLWRNPSGGGH----------------DDKAHPPIHPTKFSAGE

Query:  RGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPPLLSEADL
             D  +LY+ V +HFL  VS       T VE+ I GE F  +G+ +  + +  +  + +     +P+++ G++     + L  G T PP  L+E++L
Subjt:  RGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPPLLSEADL

Query:  LSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSCFLDARVN
        +S M+K GIGTDA++  HI  + +R Y    +  +  PT LG  L+ GY  +  +L  P +R+ +E ++  V++G      V+   +QQ +  F      
Subjt:  LSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSCFLDARVN

Query:  KQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFP------QCRNVVWLP
          + +E M+  FE       D  RA    + +CG C              YM   TA P       C  V +LP
Subjt:  KQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFP------QCRNVVWLP

AT2G32000.2 DNA topoisomerase, type IA, core

2.0e-93

35.02

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Query:  LMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDKMDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVC--TAVNHHLNIKRAHFSALIERDIHEAV
        +M  +F E+Y+ W + DP  LF+AP+ K     K  I R L  EAR C ++VLWLDCDREGENI FEV+E       +    + RA FS++ E+DI +A+
Subjt:  LMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDKMDIKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVC--TAVNHHLNIKRAHFSALIERDIHEAV

Query:  QNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAF-NIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCW
         NLV+PN+  A AVDARQEIDL++G +F+RFQT   +  + N+D        V+SYGPCQ PTLGF V+RY  I + +PE+FW +      D       W
Subjt:  QNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAF-NIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCW

Query:  TRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQR---TDLHVGLWR
         R  LFD   A +F ++ V+  TA V++V  ++ +K  P  LNT+ L K AS       +  M +AE LY  GFISYPRTE+  +      TD       
Subjt:  TRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKYPPHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQR---TDLHVGLWR

Query:  NPSGGGH----------------DDKAHPPIHPTKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRF
        NP  GG+                D   HPPI P + +A E     D  +LY+ V +HFL  VS       T VE+ I GE F  +G+ +  + +  +  +
Subjt:  NPSGGGH----------------DDKAHPPIHPTKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRF

Query:  ESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPH
         +     +P+++ G++     + L  G T PP  L+E++L+S M+K GIGTDA++  HI  + +R Y    +  +  PT LG  L+ GY  +  +L  P 
Subjt:  ESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPH

Query:  LRAIMELEMKAVSEGTKRKDEVLATCLQQMKSCFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFP-
        +R+ +E ++  V++G      V+   +QQ +  F        + +E M+  FE       D  RA    + +CG C              YM   TA P 
Subjt:  LRAIMELEMKAVSEGTKRKDEVLATCLQQMKSCFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFP-

Query:  -----QCRNVVWLP
              C  V +LP
Subjt:  -----QCRNVVWLP

AT3G42860.1 zinc knuckle (CCHC-type) family protein

6.5e-04

33.98

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Query:  CGTP-CVLRTANTTNNRGRKFYKCQSQE----CNFFVWEDNVDNGNGGNSVPWSNIRSSGTTASNLNPSRNTGRGQGCGRGQIATTFVSATGEPISDRRC
        CG   C++ T+NT  N GRKFYKC ++E    C FF W D V   + G S   SN   +G      N ++       CG G +     + TGE +  R+ 
Subjt:  CGTP-CVLRTANTTNNRGRKFYKCQSQE----CNFFVWEDNVDNGNGGNSVPWSNIRSSGTTASNLNPSRNTGRGQGCGRGQIATTFVSATGEPISDRRC

Query:  FVC
        + C
Subjt:  FVC

AT4G31210.1 DNA topoisomerase, type IA, core

3.2e-19

23.44

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Query:  LVLWLDCDREGENIAFEVVEVCT---AVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNIDSVADDK
        L+L  D DREGE IA+ ++E+     A++  + + R  F  + E  I  A+Q+  + +     A  AR+ +D  IG              FNI  +   K
Subjt:  LVLWLDCDREGENIAFEVVEVCT---AVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNIDSVADDK

Query:  -NIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNL---------FDYTCAVIFYEMCVQESTATVVNVRRQETLKYPPH
             S G  Q   L  V +R  EI   +P+E+WT+       D  +TF     +L                   E  ++     V   +   T K PP 
Subjt:  -NIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNL---------FDYTCAVIFYEMCVQESTATVVNVRRQETLKYPPH

Query:  PLNTIELEKRASRYFRMSSEHTMKVAEDLYQ---------AGFISYPRTE---------TDCFSQRTDLHVGLWRNPSGGGHDDK------AHPPIHPTK
        P  T  L++ A+     S+ HTMK+A+ LY+         AG I+Y RT+          D  S   + +   + + S   +  K      AH  I PT 
Subjt:  PLNTIELEKRASRYFRMSSEHTMKVAEDLYQ---------AGFISYPRTE---------TDCFSQRTDLHVGLWRNPSGGGHDDK------AHPPIHPTK

Query:  F----SAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGE--LFSTSGRMILARNYLDVY------------------RFESWGGSTIPTY
             S        D  KLY L+    +AC  +PA  A   ++I  A E  +F +S   +    Y  VY                  R E++   T+ + 
Subjt:  F----SAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGE--LFSTSGRMILARNYLDVY------------------RFESWGGSTIPTY

Query:  VTGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKA
          G       + L    T+ PP  SE  L+  +++ GIG  +T     + L  R Y T   N    P      +          +      A ME E+  
Subjt:  VTGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKA

Query:  VSEGTKRKDEVLATCLQQMKS-CFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDG-NYMVGCTAFPQCR
        VS G      +L     +  + C     V + ++ + +E  +E    S       +    + C  C +  +  K ++ G  Y +GC   P C+
Subjt:  VSEGTKRKDEVLATCLQQMKS-CFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDG-NYMVGCTAFPQCR

AT5G63920.1 topoisomerase 3alpha

0.0e+00

63.87

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Query:  GGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDKMD
        GG P+TVLNVAEKPSVAKSVA ILSR    R REGRSRYNKIFEF+YAI GQ C ML+TSV GHLMELEF +RYRKWHSCDP  L+ APV K VPEDK D
Subjt:  GGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDKMD

Query:  IKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKD
        IK+TLE+EAR+  WLVLWLDCDREGENIAFEVV+VC AV H+L I+RAHFSALI+RDIHEAVQNL  PN+ FA+AVDARQEIDLRIGASFTRFQTMLL+D
Subjt:  IKRTLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKD

Query:  AFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNV-RRQETLKYP
         F IDS  ++++ V+SYGPCQFPTLGF+VERYWEIQ+HEPEEFWTINCSH S++G++TF W RG+LFDY  AVI YEMCV+E TATV+NV   +E  KYP
Subjt:  AFNIDSVADDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNV-RRQETLKYP

Query:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHV-----------------------GLWRNPSGGGHDDKAHPPIHPT
        P+PLNTIELEKRASRYFR+SSEHTMKVAE+LYQAGFISYPRTETD FS RTDL                         GLWRNP+ GGHDDKAHPPIHPT
Subjt:  PHPLNTIELEKRASRYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHV-----------------------GLWRNPSGGGHDDKAHPPIHPT

Query:  KFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPPL
        KFS+GE  WS+DH  +YELVVRH+LACVSQPAV A TTVEIDIAGE FS SGR ILA+NYL+VYRFESWGGS IP Y  GQQF+PTTLTLD+ VTRPPPL
Subjt:  KFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEIDIAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPPL

Query:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSCF
        L EADLLSCMDK GIGTDATMHDHIKKLLDR YATKDANTRF+PTNLGEALVMGYDDMGY LWKP+LRA+ME +M  VS G K K EVL TCLQQMK+CF
Subjt:  LSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNLGEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSCF

Query:  LDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQF
        LDARV K KLLEAM +FFERSN +   E++  GEVV+RC LC +SDM L++NRDGN+MVGC  +PQCRN VWLPG   EA+VT++ C  C PGPVY I F
Subjt:  LDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRNRDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQF

Query:  KFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSNK
        KFRQ+ IPP ++ NHLGC+GGCDDIL+QL +ICGTGSR                                                           S  
Subjt:  KFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFIFCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSNK

Query:  GTIPITFPPILLFAHSNYVLKLCFAARGRGTSS------------SSVQRDNTRQRESSVSCSNCGTPCVLRTANTTNNRGRKFYKCQSQECNFFVWEDN
           P T P   +   +     +C   + RG +S            S     N R  ES+VSC+ CG+ CVLRTANT  NRGR+F+ C +Q C+FF WED+
Subjt:  GTIPITFPPILLFAHSNYVLKLCFAARGRGTSS------------SSVQRDNTRQRESSVSCSNCGTPCVLRTANTTNNRGRKFYKCQSQECNFFVWEDN

Query:  VDNGNGGNSVPWSNIRSSGTTASNLNPSRNTGRGQGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRGN
        ++N + GN+   SN   SG   S        G     GR    T+FVSATGEP+S  RCF CGDPSHFAN CPNR N
Subjt:  VDNGNGGNSVPWSNIRSSGTTASNLNPSRNTGRGQGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRGN

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGTCCGGCGGCCGTCCGATCACCGTCCTCAATGTGGCAGAGAAACCATCGGTGGCGAAATCTGTGGCCACCATACTCTCGAGGAACCAGGGTCTTCGAGTTCGC
GAAGGTCGCTCTCGCTACAACAAGATTTTCGAGTTCAACTACGCCATTCGAGGCCAGTCTTGCAATATGCTCGTCACCTCCGTCACTGGCCACCTCATGGAGCTC
GAGTTCGAAGAACGGTACCGCAAATGGCATTCGTGCGATCCAGTTCAGCTTTTCAACGCTCCCGTCCGCAAATTTGTCCCCGAGGACAAGATGGACATAAAGAGG
ACTTTGGAACAAGAAGCTAGAAGGTGTCAATGGCTCGTCCTTTGGCTTGATTGTGATAGAGAAGGAGAGAATATTGCATTTGAAGTGGTGGAAGTTTGCACAGCA
GTTAATCATCATCTTAACATTAAGAGAGCCCACTTCTCTGCTTTGATTGAAAGGGATATTCACGAAGCCGTGCAAAATCTTGTACAACCAAATAAATGGTTTGCT
GATGCAGTTGATGCTAGACAAGAAATTGATCTAAGAATTGGAGCTTCTTTCACTAGGTTCCAAACTATGCTGTTGAAAGATGCATTTAATATTGATTCTGTCGCA
GATGACAAAAATATTGTTTTGAGTTATGGGCCATGTCAGTTTCCTACTCTTGGCTTTGTTGTTGAGCGGTACTGGGAGATTCAATCCCATGAGCCAGAAGAATTT
TGGACGATCAACTGTTCACACAATTCTGATGATGGGATTTCTACATTTTGTTGGACAAGAGGGAATCTATTTGATTATACGTGTGCTGTTATATTTTATGAAATG
TGCGTACAAGAATCTACTGCTACAGTTGTAAATGTTAGACGACAAGAGACATTAAAGTACCCTCCTCATCCACTGAATACAATTGAGCTTGAAAAACGAGCTTCA
CGATACTTCCGAATGAGTTCTGAACACACCATGAAGGTGGCCGAAGATCTATACCAAGCAGGTTTCATTAGTTATCCTCGTACAGAGACTGATTGCTTTTCTCAA
AGGACCGATCTTCATGTAGGACTTTGGAGGAATCCTAGTGGTGGTGGGCATGATGACAAAGCCCATCCACCTATTCACCCAACCAAGTTCTCTGCTGGGGAACGC
GGATGGAGCCAAGATCACCATAAATTATATGAGCTAGTCGTTCGCCATTTCCTTGCATGTGTCTCACAGCCAGCTGTTGGTGCTGTGACTACTGTTGAAATTGAT
ATTGCTGGTGAATTGTTTTCTACATCTGGGAGAATGATACTAGCAAGAAATTACCTGGATGTTTACCGCTTTGAATCCTGGGGAGGTTCAACTATTCCAACTTAC
GTTACTGGGCAACAGTTTGTTCCAACAACATTAACTCTTGATTCGGGAGTCACAAGACCACCTCCCCTTCTGAGTGAAGCTGATTTGCTTTCTTGTATGGATAAG
GAGGGAATTGGTACAGATGCAACAATGCATGACCACATCAAGAAGCTGTTGGATAGATTTTATGCAACGAAGGATGCAAACACTCGGTTCACACCAACTAACCTT
GGTGAGGCTCTGGTTATGGGATATGATGACATGGGGTATAACCTGTGGAAACCACACCTTAGAGCAATCATGGAGCTTGAGATGAAAGCAGTTAGTGAGGGCACT
AAGAGAAAAGATGAAGTGTTGGCTACGTGCTTGCAGCAGATGAAATCTTGCTTTTTAGATGCAAGGGTCAATAAGCAAAAACTTCTTGAAGCTATGGAAGTTTTC
TTTGAGAGATCTAATGGTTCTGGCGGGGATGAAAATCGTGCAGTTGGAGAAGTTGTTCAGCGGTGTGGACTGTGTCAAGACTCAGATATGGTGCTTAAAAGAAAC
AGGGATGGAAATTACATGGTTGGATGTACGGCCTTCCCCCAGTGTAGAAATGTTGTCTGGCTCCCGGGATCCATTGCAGAAGCTGCAGTAACCTCTGATCGTTGC
AACTTGTGCACTCCAGGTCCTGTTTACTTAATCCAATTTAAGTTTCGCCAGCTGGAAATTCCACCAAACTACAATGCCAACCACTTGGGTTGTATAGGTGGTTGT
GATGATATTCTTAGGCAATTGACTGAAATCTGTGGTACTGGATCCCGCGTATCAGGCATGTACTTTTTGTGCAGTTATTTCTTCAAAATATTTGAGATGTTCATA
TTTTGTTTTTTTGTTTTTTTGGGAGTTGAGGATCAAGAAACACACAATTTAGAAGAAGGGAAACTACTCCACATGACCCAAGAAATAAAAACAAATCCTTTTGCA
GATGTCTATGATTTCAGCAACAAAGGAACAATTCCGATTACTTTTCCTCCCATTTTACTTTTTGCACATTCAAATTATGTACTCAAATTATGTTTTGCAGCTAGA
GGTCGAGGGACTTCATCTTCCAGTGTGCAGCGAGATAACACCAGGCAAAGAGAATCTTCGGTTTCATGTAGTAACTGTGGCACACCATGCGTCTTACGGACTGCT
AATACTACCAATAATAGAGGAAGAAAGTTCTACAAATGTCAATCTCAGGAGTGCAATTTCTTCGTATGGGAAGACAACGTAGACAATGGCAATGGAGGAAATAGT
GTTCCATGGTCAAATATCAGGAGCTCAGGCACCACAGCATCTAATCTTAACCCTAGTCGAAACACTGGACGTGGTCAAGGTTGTGGTCGGGGTCAGATTGCAACG
ACATTCGTGTCAGCTACTGGTGAGCCAATATCTGATAGAAGATGTTTTGTTTGTGGCGATCCATCACACTTTGCAAATGTTTGCCCTAACCGCGGCAACTTCACA
TATTTTTTCATCTTTGAATTTGGTTCCTGA

mRNA sequence

Show/hide mRNA sequence

AAACATTTTCCAAAAAAGGAAAAACCCAATTTATTCCTTCCCGCCATTTCGTCTAAAACCCTCCAAAATCTCAGAGCTGTTGCTCGGACACGGGGCGGTTCAGTA
GCCATGTCCGGCGGCCGTCCGATCACCGTCCTCAATGTGGCAGAGAAACCATCGGTGGCGAAATCTGTGGCCACCATACTCTCGAGGAACCAGGGTCTTCGAGTT
CGCGAAGGTCGCTCTCGCTACAACAAGATTTTCGAGTTCAACTACGCCATTCGAGGCCAGTCTTGCAATATGCTCGTCACCTCCGTCACTGGCCACCTCATGGAG
CTCGAGTTCGAAGAACGGTACCGCAAATGGCATTCGTGCGATCCAGTTCAGCTTTTCAACGCTCCCGTCCGCAAATTTGTCCCCGAGGACAAGATGGACATAAAG
AGGACTTTGGAACAAGAAGCTAGAAGGTGTCAATGGCTCGTCCTTTGGCTTGATTGTGATAGAGAAGGAGAGAATATTGCATTTGAAGTGGTGGAAGTTTGCACA
GCAGTTAATCATCATCTTAACATTAAGAGAGCCCACTTCTCTGCTTTGATTGAAAGGGATATTCACGAAGCCGTGCAAAATCTTGTACAACCAAATAAATGGTTT
GCTGATGCAGTTGATGCTAGACAAGAAATTGATCTAAGAATTGGAGCTTCTTTCACTAGGTTCCAAACTATGCTGTTGAAAGATGCATTTAATATTGATTCTGTC
GCAGATGACAAAAATATTGTTTTGAGTTATGGGCCATGTCAGTTTCCTACTCTTGGCTTTGTTGTTGAGCGGTACTGGGAGATTCAATCCCATGAGCCAGAAGAA
TTTTGGACGATCAACTGTTCACACAATTCTGATGATGGGATTTCTACATTTTGTTGGACAAGAGGGAATCTATTTGATTATACGTGTGCTGTTATATTTTATGAA
ATGTGCGTACAAGAATCTACTGCTACAGTTGTAAATGTTAGACGACAAGAGACATTAAAGTACCCTCCTCATCCACTGAATACAATTGAGCTTGAAAAACGAGCT
TCACGATACTTCCGAATGAGTTCTGAACACACCATGAAGGTGGCCGAAGATCTATACCAAGCAGGTTTCATTAGTTATCCTCGTACAGAGACTGATTGCTTTTCT
CAAAGGACCGATCTTCATGTAGGACTTTGGAGGAATCCTAGTGGTGGTGGGCATGATGACAAAGCCCATCCACCTATTCACCCAACCAAGTTCTCTGCTGGGGAA
CGCGGATGGAGCCAAGATCACCATAAATTATATGAGCTAGTCGTTCGCCATTTCCTTGCATGTGTCTCACAGCCAGCTGTTGGTGCTGTGACTACTGTTGAAATT
GATATTGCTGGTGAATTGTTTTCTACATCTGGGAGAATGATACTAGCAAGAAATTACCTGGATGTTTACCGCTTTGAATCCTGGGGAGGTTCAACTATTCCAACT
TACGTTACTGGGCAACAGTTTGTTCCAACAACATTAACTCTTGATTCGGGAGTCACAAGACCACCTCCCCTTCTGAGTGAAGCTGATTTGCTTTCTTGTATGGAT
AAGGAGGGAATTGGTACAGATGCAACAATGCATGACCACATCAAGAAGCTGTTGGATAGATTTTATGCAACGAAGGATGCAAACACTCGGTTCACACCAACTAAC
CTTGGTGAGGCTCTGGTTATGGGATATGATGACATGGGGTATAACCTGTGGAAACCACACCTTAGAGCAATCATGGAGCTTGAGATGAAAGCAGTTAGTGAGGGC
ACTAAGAGAAAAGATGAAGTGTTGGCTACGTGCTTGCAGCAGATGAAATCTTGCTTTTTAGATGCAAGGGTCAATAAGCAAAAACTTCTTGAAGCTATGGAAGTT
TTCTTTGAGAGATCTAATGGTTCTGGCGGGGATGAAAATCGTGCAGTTGGAGAAGTTGTTCAGCGGTGTGGACTGTGTCAAGACTCAGATATGGTGCTTAAAAGA
AACAGGGATGGAAATTACATGGTTGGATGTACGGCCTTCCCCCAGTGTAGAAATGTTGTCTGGCTCCCGGGATCCATTGCAGAAGCTGCAGTAACCTCTGATCGT
TGCAACTTGTGCACTCCAGGTCCTGTTTACTTAATCCAATTTAAGTTTCGCCAGCTGGAAATTCCACCAAACTACAATGCCAACCACTTGGGTTGTATAGGTGGT
TGTGATGATATTCTTAGGCAATTGACTGAAATCTGTGGTACTGGATCCCGCGTATCAGGCATGTACTTTTTGTGCAGTTATTTCTTCAAAATATTTGAGATGTTC
ATATTTTGTTTTTTTGTTTTTTTGGGAGTTGAGGATCAAGAAACACACAATTTAGAAGAAGGGAAACTACTCCACATGACCCAAGAAATAAAAACAAATCCTTTT
GCAGATGTCTATGATTTCAGCAACAAAGGAACAATTCCGATTACTTTTCCTCCCATTTTACTTTTTGCACATTCAAATTATGTACTCAAATTATGTTTTGCAGCT
AGAGGTCGAGGGACTTCATCTTCCAGTGTGCAGCGAGATAACACCAGGCAAAGAGAATCTTCGGTTTCATGTAGTAACTGTGGCACACCATGCGTCTTACGGACT
GCTAATACTACCAATAATAGAGGAAGAAAGTTCTACAAATGTCAATCTCAGGAGTGCAATTTCTTCGTATGGGAAGACAACGTAGACAATGGCAATGGAGGAAAT
AGTGTTCCATGGTCAAATATCAGGAGCTCAGGCACCACAGCATCTAATCTTAACCCTAGTCGAAACACTGGACGTGGTCAAGGTTGTGGTCGGGGTCAGATTGCA
ACGACATTCGTGTCAGCTACTGGTGAGCCAATATCTGATAGAAGATGTTTTGTTTGTGGCGATCCATCACACTTTGCAAATGTTTGCCCTAACCGCGGCAACTTC
ACATATTTTTTCATCTTTGAATTTGGTTCCTGA

Protein sequence

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MSGGRPITVLNVAEKPSVAKSVATILSRNQGLRVREGRSRYNKIFEFNYAIRGQSCNMLVTSVTGHLMELEFEERYRKWHSCDPVQLFNAPVRKFVPEDKMDIKR
TLEQEARRCQWLVLWLDCDREGENIAFEVVEVCTAVNHHLNIKRAHFSALIERDIHEAVQNLVQPNKWFADAVDARQEIDLRIGASFTRFQTMLLKDAFNIDSVA
DDKNIVLSYGPCQFPTLGFVVERYWEIQSHEPEEFWTINCSHNSDDGISTFCWTRGNLFDYTCAVIFYEMCVQESTATVVNVRRQETLKYPPHPLNTIELEKRAS
RYFRMSSEHTMKVAEDLYQAGFISYPRTETDCFSQRTDLHVGLWRNPSGGGHDDKAHPPIHPTKFSAGERGWSQDHHKLYELVVRHFLACVSQPAVGAVTTVEID
IAGELFSTSGRMILARNYLDVYRFESWGGSTIPTYVTGQQFVPTTLTLDSGVTRPPPLLSEADLLSCMDKEGIGTDATMHDHIKKLLDRFYATKDANTRFTPTNL
GEALVMGYDDMGYNLWKPHLRAIMELEMKAVSEGTKRKDEVLATCLQQMKSCFLDARVNKQKLLEAMEVFFERSNGSGGDENRAVGEVVQRCGLCQDSDMVLKRN
RDGNYMVGCTAFPQCRNVVWLPGSIAEAAVTSDRCNLCTPGPVYLIQFKFRQLEIPPNYNANHLGCIGGCDDILRQLTEICGTGSRVSGMYFLCSYFFKIFEMFI
FCFFVFLGVEDQETHNLEEGKLLHMTQEIKTNPFADVYDFSNKGTIPITFPPILLFAHSNYVLKLCFAARGRGTSSSSVQRDNTRQRESSVSCSNCGTPCVLRTA
NTTNNRGRKFYKCQSQECNFFVWEDNVDNGNGGNSVPWSNIRSSGTTASNLNPSRNTGRGQGCGRGQIATTFVSATGEPISDRRCFVCGDPSHFANVCPNRGNFT
YFFIFEFGS

CmUC10G198150 (gene) of Watermelon (USVL531) v1 genome