CuGenDBv2

Gene ID	Cmc02g0055941
Organism	Cucumis melo var. cantalupensis cv. Charmono (Melon (Charmono) v1.1)
Description	protein MIS12 homolog
Genome location	CMiso1.1chr02:22441854..22444750
RNA-Seq Expression	Cmc02g0055941
Synteny	Cmc02g0055941
Gene Ontology terms	GO:0000070 - mitotic sister chromatid segregation (biological process) GO:0034501 - protein localization to kinetochore (biological process) GO:0051301 - cell division (biological process) GO:0051382 - kinetochore assembly (biological process) GO:0000444 - MIS12/MIND type complex (cellular component) GO:0005634 - nucleus (cellular component)
InterPro domains	IPR008685 - Centromere protein Mis12

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAA0058004.1 Centromere protein Mis12 [Cucumis melo var. makuwa]

1.1e-124

99.16

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Query:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN
        MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASA LKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN
Subjt:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN

Query:  DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTEEA
        DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELR+KIGKMKKRRTEEA
Subjt:  DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTEEA

Query:  KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI
        KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI
Subjt:  KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI

KAA0058032.1 Centromere protein Mis12 [Cucumis melo var. makuwa]

1.3e-125

100

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Query:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN
        MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN
Subjt:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN

Query:  DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTEEA
        DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTEEA
Subjt:  DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTEEA

Query:  KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI
        KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI
Subjt:  KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI

XP_004138204.3 protein MIS12 homolog isoform X1 [Cucumis sativus]

9.5e-116

94.14

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Query:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN
        MEGSKGE VFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASA LKTE SDRSQDLTLGISQVRALVQLGL KRLAMWEKYCLNHCFSVPEGFSLPS+
Subjt:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN

Query:  DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTEEA
        DESPGVTSI+HD DVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMI+TASELR KIGK+KK RTEE 
Subjt:  DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTEEA

Query:  KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI
        KLA VEKVHTNGDISHHH GFSNAKLDDIQEFLSDLKKI
Subjt:  KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI

XP_023515499.1 protein MIS12 homolog isoform X2 [Cucurbita pepo subsp. pepo]

2.1e-107

85.06

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Query:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN
        MEGSKGE VF+SLNLNPQLFINEALN VDDLVDDAFDFYQ+QASA+LKTEGSDRSQDL+LGIS+VR  VQ GLDKRLAMWEKYCLNHCFSVPEGFSLPSN
Subjt:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN

Query:  DESPGVTSINHD--QDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTE
        DESP VTS++ D   DVDLDTELD LRNKLSEVRKEN+VLNQELQALERQTASSNSQ++ FNEALQLYEQ+SVN+MFQEM+ TASELR+KIGK+KKRR E
Subjt:  DESPGVTSINHD--QDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTE

Query:  EAKLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI
        E+KL KVEK+HTNGDISHHH GFSNAKLDDIQEFL+DLK +
Subjt:  EAKLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI

XP_038879945.1 protein MIS12 homolog [Benincasa hispida]

9.2e-111

88.28

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Query:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN
        MEGSKGE+VF+SLNLNPQLFINEALN VDDLVDDAF FYQSQASATLKTEGSDRSQDLTLGIS+VRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN
Subjt:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN

Query:  DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTEEA
        D+SPGVTSI+HD DV LDTELD LRNKLSEVRKENIVLNQELQALERQTA+SNSQI+HFNEALQLYEQ+SVN+MFQEM+ TASELR+KIGK+KKRR EE+
Subjt:  DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTEEA

Query:  KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI
        KL KVEKVHTNGDISH+HNG SNAKLDDI+ FL DLK +
Subjt:  KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LPL2 Uncharacterized protein

3.0e-115

93.72

Show/hide

Query:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN
        MEGSKGE VFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASA LKTE SDRSQDLTLGISQVRALVQLGL KRLAMWEKYCLNHCFSVPEGFSLPS+
Subjt:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN

Query:  DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTEEA
        DESPGVTSI+HD DVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMI+TASELR KIGK+KK RTEE 
Subjt:  DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTEEA

Query:  KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI
        KLA VEKVHTNGDISHHH GFSNAKLDDIQEFLS LKKI
Subjt:  KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI

A0A5A7UQ95 Centromere protein Mis12

6.4e-126

100

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Query:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN
        MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN
Subjt:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN

Query:  DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTEEA
        DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTEEA
Subjt:  DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTEEA

Query:  KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI
        KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI
Subjt:  KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI

A0A5A7US57 Centromere protein Mis12

5.4e-125

99.16

Show/hide

Query:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN
        MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASA LKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN
Subjt:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN

Query:  DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTEEA
        DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELR+KIGKMKKRRTEEA
Subjt:  DESPGVTSINHDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTEEA

Query:  KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI
        KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI
Subjt:  KLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI

A0A6J1E0A1 protein MIS12 homolog

5.6e-106

84.23

Show/hide

Query:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN
        MEGSKGE VF+SLNLNPQLFINEALN VDDLVDDAFDFYQ+QASA+LKTEGSDRSQDL LGIS+VR  VQ GLDKRLAMWEKYCLNHCFSVPEGFSLPSN
Subjt:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN

Query:  DESPGVTSINHD--QDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTE
        DESP VTS++ D   DVDLDTELD LRNKLSEVRKENIVLNQELQALERQ ASSNSQ++ FNEALQLYE++SVN+MFQEM+ TASELR+KIGK+KKRR E
Subjt:  DESPGVTSINHD--QDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTE

Query:  EAKLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI
        E+KL KVEK+HTNGD SHHH GFSNAKLDDIQEFL+DLK +
Subjt:  EAKLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI

A0A6J1JME3 protein MIS12 homolog isoform X2

2.1e-105

84.23

Show/hide

Query:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN
        MEGSKGE VF+SLNLNPQLFINEALN VDDLVDDAFDFYQ+QASA+LKTEGSDRSQDL LGIS+VR  VQ GLDKRLAMWEKYCLNHCFSVPEGFSLPSN
Subjt:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSN

Query:  DESPGVTSINHD--QDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTE
        DESP VTS++ D   DVDLDTELD LR  LSEVRKENIVLNQELQALERQTASSNSQ++ FNEALQLYEQ+SVN+MFQEM+ TASELR+KIGK+KKRR E
Subjt:  DESPGVTSINHD--QDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTE

Query:  EAKLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI
        E+KL KVEK+HTN DISHHH GFSNAKLDDIQEFL+DLK +
Subjt:  EAKLAKVEKVHTNGDISHHHNGFSNAKLDDIQEFLSDLKKI

SwissProt top hits

e value

%identity

Alignment

Q2V0Z5 Protein MIS12 homolog

4.5e-52

46.96

Show/hide

Query:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSD--RSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLP
        MEGSK E+VF+S+NLNPQ+FINEA+N+V+D VD AFDFY   AS +LK +GSD  +SQ L+ GI++VR L+   +D RL +WE Y L  CF+VP+GF LP
Subjt:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSD--RSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLP

Query:  SNDESPGVTSINHD--QDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRR
         ++ES   +S++ D   D++LD ELD LR+KL+ V K ++ L+ ELQALER + S    +   NEAL+LY++SS++++F+EM K ASELR+ + ++K RR
Subjt:  SNDESPGVTSINHD--QDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRR

Query:  TEEAKLAKVEKVHTNGDISHHHNGFS----NAKLDDIQEFLSDLKKI
         + ++ AKV++      + +H   FS    + KL+D+++F ++L+K+
Subjt:  TEEAKLAKVEKVHTNGDISHHHNGFS----NAKLDDIQEFLSDLKKI

Arabidopsis top hits

e value

%identity

Alignment

AT5G35520.1 minichromosome instability 12 (mis12)-like

3.2e-53

46.96

Show/hide

Query:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSD--RSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLP
        MEGSK E+VF+S+NLNPQ+FINEA+N+V+D VD AFDFY   AS +LK +GSD  +SQ L+ GI++VR L+   +D RL +WE Y L  CF+VP+GF LP
Subjt:  MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSD--RSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLP

Query:  SNDESPGVTSINHD--QDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRR
         ++ES   +S++ D   D++LD ELD LR+KL+ V K ++ L+ ELQALER + S    +   NEAL+LY++SS++++F+EM K ASELR+ + ++K RR
Subjt:  SNDESPGVTSINHD--QDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRR

Query:  TEEAKLAKVEKVHTNGDISHHHNGFS----NAKLDDIQEFLSDLKKI
         + ++ AKV++      + +H   FS    + KL+D+++F ++L+K+
Subjt:  TEEAKLAKVEKVHTNGDISHHHNGFS----NAKLDDIQEFLSDLKKI

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGGAAGGAAGTAAAGGCGAATCGGTATTCAATTCCCTCAATCTCAATCCACAGCTCTTCATTAATGAAGCTCTCAATACTGTCGACGATTTGGTTGATGATGCTTTCGA
TTTCTATCAATCACAAGCATCGGCTACCTTGAAGACCGAGGGCTCGGATAGATCTCAGGATCTTACTCTGGGAATATCGCAAGTCCGAGCGTTGGTCCAATTGGGTCTGG
ATAAGCGATTGGCCATGTGGGAAAAGTACTGTCTTAATCACTGTTTTTCAGTGCCTGAAGGTTTTTCTTTACCCTCAAATGATGAATCACCTGGTGTCACTTCAATAAAT
CATGACCAAGACGTGGATCTGGATACAGAGCTAGATCTTTTGAGAAATAAGCTCTCCGAGGTCAGAAAAGAGAATATTGTATTAAACCAAGAGCTACAAGCTTTGGAAAG
GCAAACTGCTTCCAGTAACTCCCAAATCAGTCATTTCAACGAAGCATTACAACTATATGAGCAAAGTTCTGTGAATGACATGTTCCAGGAAATGATCAAAACTGCATCAG
AGCTCCGTTCAAAAATAGGAAAGATGAAGAAAAGGAGGACGGAGGAAGCCAAGCTCGCTAAAGTAGAGAAGGTTCATACAAATGGAGACATCTCTCACCATCACAATGGT
TTCTCTAATGCTAAGCTGGATGATATTCAAGAATTTTTATCTGATTTGAAGAAGATTTGA

mRNA sequence

Show/hide mRNA sequence

Protein sequence

Show/hide protein sequence

MEGSKGESVFNSLNLNPQLFINEALNTVDDLVDDAFDFYQSQASATLKTEGSDRSQDLTLGISQVRALVQLGLDKRLAMWEKYCLNHCFSVPEGFSLPSNDESPGVTSIN
HDQDVDLDTELDLLRNKLSEVRKENIVLNQELQALERQTASSNSQISHFNEALQLYEQSSVNDMFQEMIKTASELRSKIGKMKKRRTEEAKLAKVEKVHTNGDISHHHNG
FSNAKLDDIQEFLSDLKKI

Cmc02g0055941 (gene) of Melon (Charmono) v1.1 genome