CuGenDBv2

Gene ID	Cmc06g0172071
Organism	Cucumis melo var. cantalupensis cv. Charmono (Melon (Charmono) v1.1)
Description	Reverse transcriptase
Genome location	CMiso1.1chr06:27933111..27933578
RNA-Seq Expression	Cmc06g0172071
Synteny	Cmc06g0172071
Gene Ontology terms	GO:0006278 - RNA-dependent DNA biosynthetic process (biological process) GO:0006355 - regulation of transcription, DNA-templated (biological process) GO:0006508 - proteolysis (biological process) GO:0015074 - DNA integration (biological process) GO:0003700 - DNA-binding transcription factor activity (molecular function) GO:0003964 - RNA-directed DNA polymerase activity (molecular function) GO:0004190 - aspartic-type endopeptidase activity (molecular function) GO:0008270 - zinc ion binding (molecular function) GO:0043565 - sequence-specific DNA binding (molecular function)
InterPro domains	IPR000477 - Reverse transcriptase domain IPR043128 - Reverse transcriptase/Diguanylate cyclase domain IPR043502 - DNA/RNA polymerase superfamily

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0041715.1 pol protein [Cucumis melo var. makuwa]

4.1e-59

81.51

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Query:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW
        MSFGLTNAP + MDLMN VF++FLDTFVIVFIDDIL+YSK EAEHE+HLCMVL+TLR NKLYAK S  +F LKQVSFLGHVV+K GVSV PAKIEAVTSW
Subjt:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW

Query:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIGGPFVWS
        ++PSTV+EVRSFLGLAGYYRRFVE+FS IATP TQLTR G PFVWS
Subjt:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIGGPFVWS

KAA0042119.1 pol protein [Cucumis melo var. makuwa]

1.3e-57

81.51

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Query:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW
        MSFGLTNAP + MDLMN VF++FLDTFVIVFIDDIL+YSK EAEHEEHL MVL+TLR NKLYAK S  +F LKQVSFLGHVV K GVSV PAKIEAVTSW
Subjt:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW

Query:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIGGPFVWS
        ++PSTV+EVRSFLGLAGYYRRFVE+FS IATP TQLTR G PFVWS
Subjt:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIGGPFVWS

KAA0047130.1 reverse transcriptase [Cucumis melo var. makuwa]

3.4e-58

82.19

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Query:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW
        MSFGLTNAPTM MDLMN VF++FLDTFVIVFIDDIL+YSK EAEHEEHL +VL+TLR NKLYAK S  +F LKQVSFLGHVV K GVSV PAKIEAVT W
Subjt:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW

Query:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIGGPFVWS
        +QPSTV+EVRSFLGLAGYYRRFVE+FS IATP TQLTR G PFVWS
Subjt:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIGGPFVWS

KAA0062265.1 ty3-gypsy retrotransposon protein [Cucumis melo var. makuwa]

1.3e-57

81.51

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Query:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW
        MSFGLTNAP + MDLMN VF++FLDTFVIVFIDDIL+YSK EAEHEEHL MVL+TLR NKLYAK S  +F LKQVSFLGHVV K GVSV PAKIEAVT W
Subjt:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW

Query:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIGGPFVWS
        +QPSTV+EVRSFLGLAGYYRRFVE+FS IATP TQLTR G PFVWS
Subjt:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIGGPFVWS

TYK03208.1 reverse transcriptase [Cucumis melo var. makuwa]

2.0e-66

95.71

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Query:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW
        MSFGL NAPTM MDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKL AKLSNF+FLLKQVSFLGHVVFKEGVSV PAKIEAVTSW
Subjt:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW

Query:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIG
        SQPSTV+EVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIG
Subjt:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIG

TrEMBL top hits

e value

%identity

Alignment

A0A5A7TJV4 Pol protein

2.0e-59

81.51

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Query:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW
        MSFGLTNAP + MDLMN VF++FLDTFVIVFIDDIL+YSK EAEHE+HLCMVL+TLR NKLYAK S  +F LKQVSFLGHVV+K GVSV PAKIEAVTSW
Subjt:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW

Query:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIGGPFVWS
        ++PSTV+EVRSFLGLAGYYRRFVE+FS IATP TQLTR G PFVWS
Subjt:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIGGPFVWS

A0A5A7TLA3 Pol protein

6.3e-58

81.51

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Query:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW
        MSFGLTNAP + MDLMN VF++FLDTFVIVFIDDIL+YSK EAEHEEHL MVL+TLR NKLYAK S  +F LKQVSFLGHVV K GVSV PAKIEAVTSW
Subjt:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW

Query:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIGGPFVWS
        ++PSTV+EVRSFLGLAGYYRRFVE+FS IATP TQLTR G PFVWS
Subjt:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIGGPFVWS

A0A5A7TVD9 Reverse transcriptase

1.7e-58

82.19

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Query:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW
        MSFGLTNAPTM MDLMN VF++FLDTFVIVFIDDIL+YSK EAEHEEHL +VL+TLR NKLYAK S  +F LKQVSFLGHVV K GVSV PAKIEAVT W
Subjt:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW

Query:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIGGPFVWS
        +QPSTV+EVRSFLGLAGYYRRFVE+FS IATP TQLTR G PFVWS
Subjt:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIGGPFVWS

A0A5A7V8N8 Ty3-gypsy retrotransposon protein

6.3e-58

81.51

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Query:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW
        MSFGLTNAP + MDLMN VF++FLDTFVIVFIDDIL+YSK EAEHEEHL MVL+TLR NKLYAK S  +F LKQVSFLGHVV K GVSV PAKIEAVT W
Subjt:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW

Query:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIGGPFVWS
        +QPSTV+EVRSFLGLAGYYRRFVE+FS IATP TQLTR G PFVWS
Subjt:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIGGPFVWS

A0A5D3BW62 Reverse transcriptase

9.7e-67

95.71

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Query:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW
        MSFGL NAPTM MDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKL AKLSNF+FLLKQVSFLGHVVFKEGVSV PAKIEAVTSW
Subjt:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW

Query:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIG
        SQPSTV+EVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIG
Subjt:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTRIG

SwissProt top hits

e value

%identity

Alignment

P04323 Retrovirus-related Pol polyprotein from transposon 17.6

7.0e-22

38.52

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Query:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW
        M FGL NAP      MN + +  L+   +V++DDI+++S    EH + L +V E L    L  +L   +FL ++ +FLGHV+  +G+   P KIEA+  +
Subjt:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW

Query:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQ
          P+   E+++FLGL GYYR+F+ +F+ IA P T+
Subjt:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQ

P10401 Retrovirus-related Pol polyprotein from transposon gypsy

1.1e-19

33.33

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Query:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW
        + FGL NA ++    ++ V ++ +     V++DD++++S+ E++H  H+  VL+ L    +       +F  + V +LG +V K+G    P K++A+  +
Subjt:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW

Query:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTR
         +P  V +VRSFLGLA YYR F++DF+ IA P T + +
Subjt:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTR

P20825 Retrovirus-related Pol polyprotein from transposon 297

2.0e-21

37.31

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Query:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW
        M FGL NAP      MN + +  L+   +V++DDI+++S    EH   + +V   L    L  +L   +FL K+ +FLGH+V  +G+   P K++A+ S+
Subjt:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW

Query:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFT
          P+   E+R+FLGL GYYR+F+ +++ IA P T
Subjt:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFT

Q8I7P9 Retrovirus-related Pol polyprotein from transposon opus

3.5e-21

34.78

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Query:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW
        + FGL NAP +   +++ + ++ +     V+IDDI+++S+    H ++L +VL +L    L   L    FL  QV FLG++V  +G+   P K+ A++  
Subjt:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW

Query:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTR
          P++V E++ FLG+  YYR+F++D++ +A P T LTR
Subjt:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTR

Q99315 Transposon Ty3-G Gag-Pol polyprotein

3.1e-17

37.88

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Query:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW
        M FGL NAP+     M   F+D    FV V++DDIL++S+   EH +HL  VLE L+   L  K    KF  ++  FLG+ +  + ++    K  A+  +
Subjt:  MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSW

Query:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATP
          P TV + + FLG+  YYRRF+ + S IA P
Subjt:  SQPSTVNEVRSFLGLAGYYRRFVEDFSHIATP

Arabidopsis top hits

e value

%identity

Alignment

ATMG00860.1 DNA/RNA polymerases superfamily protein

1.2e-16

43.01

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Query:  HLCMVLETLRTNKLYAKLSNFKFLLKQVSFLG--HVVFKEGVSVYPAKIEAVTSWSQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTR
        HL MVL+    ++ YA      F   Q+++LG  H++  EGVS  PAK+EA+  W +P    E+R FLGL GYYRRFV+++  I  P T+L +
Subjt:  HLCMVLETLRTNKLYAKLSNFKFLLKQVSFLG--HVVFKEGVSVYPAKIEAVTSWSQPSTVNEVRSFLGLAGYYRRFVEDFSHIATPFTQLTR

Sequences

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CDS sequence

Show/hide CDS sequence

ATGTCTTTTGGATTGACGAATGCTCCAACAATGCTTATGGATTTGATGAACATAGTGTTTAAGGATTTCTTAGACACTTTTGTAATTGTGTTTATTGATGATATCTTGCT
GTATTCCAAGAAAGAGGCAGAACATGAAGAGCATTTATGCATGGTTCTAGAGACCCTTAGAACCAATAAACTATATGCCAAGTTGTCAAATTTTAAGTTTTTGTTGAAGC
AGGTATCTTTTCTAGGCCATGTGGTTTTTAAAGAAGGTGTTTCTGTGTATCCAGCTAAGATAGAAGCTGTTACCAGTTGGTCCCAACCTTCCACAGTTAATGAAGTTCGT
AGCTTTCTTGGTTTAGCAGGCTATTATCGACGGTTTGTGGAAGACTTCTCCCATATAGCTACTCCCTTTACTCAGTTGACTAGGATAGGAGGTCCATTTGTTTGGAGCTG
TAACCCCCCAAAATTTAAGGCAATTTAG

mRNA sequence

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Protein sequence

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MSFGLTNAPTMLMDLMNIVFKDFLDTFVIVFIDDILLYSKKEAEHEEHLCMVLETLRTNKLYAKLSNFKFLLKQVSFLGHVVFKEGVSVYPAKIEAVTSWSQPSTVNEVR
SFLGLAGYYRRFVEDFSHIATPFTQLTRIGGPFVWSCNPPKFKAI

Cmc06g0172071 (gene) of Melon (Charmono) v1.1 genome