CuGenDBv2

Gene ID	CmoCh08G011870
Organism	Cucurbita moschata Rifu (Cucurbita moschata (Rifu) v1)
Description	E3 ubiquitin-protein ligase Topors isoform X1
Genome location	Cmo_Chr08:7547250..7549998
RNA-Seq Expression	CmoCh08G011870
Synteny	CmoCh08G011870
Gene Ontology terms	GO:0000209 - protein polyubiquitination (biological process) GO:0006513 - protein monoubiquitination (biological process) GO:0046872 - metal ion binding (molecular function) GO:0061630 - ubiquitin protein ligase activity (molecular function)
InterPro domains	NA

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6593954.1 E3 ubiquitin-protein ligase Topors, partial [Cucurbita argyrosperma subsp. sororia]

4.7e-115

79.78

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Query:  MLEGKIMKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERL
        ML GKIM HS  EPARKL GENFVV                                             KRTCPLCNAQFDSWFSKIKLSSRSFRKERL
Subjt:  MLEGKIMKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERL

Query:  PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEA
        PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQA PSSVRSCLVMNLTGSHGVKEA
Subjt:  PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEA

Query:  ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI
        ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELR F   S+
Subjt:  ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI

KAG7026294.1 E3 ubiquitin-protein ligase Topors, partial [Cucurbita argyrosperma subsp. argyrosperma]

1.9e-111

79.34

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Query:  MKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERLPNLNCA
        M HS  EPARKL GENFVV                                             KRTCPLCNAQFDSWFSKIKLSSRSFRKERLPNLNCA
Subjt:  MKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERLPNLNCA

Query:  DNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEAILERIK
        DNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDR IQA PSSVRSCLVMNLTGSHGVKEAILERIK
Subjt:  DNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEAILERIK

Query:  PWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI
        PWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELR F   S+
Subjt:  PWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI

XP_022930345.1 E3 ubiquitin-protein ligase Topors isoform X1 [Cucurbita moschata]

2.5e-116

80.14

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Query:  MLEGKIMKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERL
        ML GKI KHS  EPARKLNGENFVV                                             KRTCPLCNAQFDSWFSKIKLSSRSFRKERL
Subjt:  MLEGKIMKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERL

Query:  PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEA
        PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQA+PSSVRSCLVMNLTGSHGVKEA
Subjt:  PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEA

Query:  ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI
        ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELR F   S+
Subjt:  ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI

XP_022999966.1 E3 ubiquitin-protein ligase Topors isoform X1 [Cucurbita maxima]

1.3e-117

80.51

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Query:  MLEGKIMKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERL
        MLEGKIMKHS GEPARKLNGENFVV                                             KRTCPLCNAQFDSWF KI LSSRSFRKERL
Subjt:  MLEGKIMKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERL

Query:  PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEA
        PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQA+PSSVRSCLVMNLTGSHGVKEA
Subjt:  PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEA

Query:  ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI
        ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELR F   S+
Subjt:  ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI

XP_023514952.1 E3 ubiquitin-protein ligase Topors [Cucurbita pepo subsp. pepo]

5.4e-111

78.6

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Query:  MKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERLPNLNCA
        M+HS  EPARKLNGENFVV                                             KRTCPLCNAQFDSWF  IKLSSRSFRKERLPNLNCA
Subjt:  MKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERLPNLNCA

Query:  DNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEAILERIK
        DNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWR SIYDRRIQA+PSSVRSCLVMNLT SHGVKEAILERIK
Subjt:  DNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEAILERIK

Query:  PWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI
        PWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELR F   S+
Subjt:  PWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KCD1 RING-type domain-containing protein

1.8e-88

63.74

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Query:  LEGKIMKHSAG--EPARKLNGENFV---------------------------------------------VKRTCPLCNAQFDSWFSKIKLSSRSFRKER
        L+ ++MK S+   EPARKLNGENF+                                             +KRTCPLCNAQFDSWF+KI LSS+SFRKER
Subjt:  LEGKIMKHSAG--EPARKLNGENFV---------------------------------------------VKRTCPLCNAQFDSWFSKIKLSSRSFRKER

Query:  LPNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKE
        L   NC+D LK+G+GSS+ DAR ILQSTR EL+R+RRSER LTWRRSFGRRGP+S+P DV+  RK QWRASIY+R IQA+PSSVRSCL +N+ GS G KE
Subjt:  LPNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKE

Query:  AILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYF
         ILERIKPWIQREL+ IL DPDPTIIVHLV SLFVAR+EA SSQLNAE+DFLSPLRPFL+EKTDLFWHELR F
Subjt:  AILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYF

A0A6J1EQ79 E3 ubiquitin-protein ligase Topors isoform X1

1.2e-116

80.14

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Query:  MLEGKIMKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERL
        ML GKI KHS  EPARKLNGENFVV                                             KRTCPLCNAQFDSWFSKIKLSSRSFRKERL
Subjt:  MLEGKIMKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERL

Query:  PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEA
        PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQA+PSSVRSCLVMNLTGSHGVKEA
Subjt:  PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEA

Query:  ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI
        ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELR F   S+
Subjt:  ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI

A0A6J1EUW6 E3 ubiquitin-protein ligase Topors isoform X2

2.3e-91

67.87

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Query:  MLEGKIMKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERL
        ML GKI KHS  EPARKLNGENFVV                                             KRTCPLCNAQFDSWFSKIKLSSRSFRKERL
Subjt:  MLEGKIMKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERL

Query:  PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEA
        PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQA+PSSVRSCLVMNLTGSHGVKEA
Subjt:  PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEA

Query:  ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI
        ILERIKPWIQRELEAI                                  LSPLRPFLYEKTDLFWHELR F   S+
Subjt:  ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI

A0A6J1KC79 E3 ubiquitin-protein ligase Topors isoform X2

1.2e-92

68.23

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Query:  MLEGKIMKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERL
        MLEGKIMKHS GEPARKLNGENFVV                                             KRTCPLCNAQFDSWF KI LSSRSFRKERL
Subjt:  MLEGKIMKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERL

Query:  PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEA
        PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQA+PSSVRSCLVMNLTGSHGVKEA
Subjt:  PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEA

Query:  ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI
        ILERIKPWIQRELEAI                                  LSPLRPFLYEKTDLFWHELR F   S+
Subjt:  ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI

A0A6J1KEK6 E3 ubiquitin-protein ligase Topors isoform X1

6.5e-118

80.51

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Query:  MLEGKIMKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERL
        MLEGKIMKHS GEPARKLNGENFVV                                             KRTCPLCNAQFDSWF KI LSSRSFRKERL
Subjt:  MLEGKIMKHSAGEPARKLNGENFVV---------------------------------------------KRTCPLCNAQFDSWFSKIKLSSRSFRKERL

Query:  PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEA
        PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQA+PSSVRSCLVMNLTGSHGVKEA
Subjt:  PNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEA

Query:  ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI
        ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELR F   S+
Subjt:  ILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLFWHELRYFTHCSI

SwissProt top hits	e value	%identity	Alignment
No hits found

Arabidopsis top hits

e value

%identity

Alignment

AT2G39100.1 RING/U-box superfamily protein

3.8e-46

47.34

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Query:  KRTCPLCNAQFDSWFSKIKLSSRSFRKERLPNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRAS
        KR CPLCN +FDSWF     +SR + KE+LP L   + L     ++ +D RRI+Q +R+ L       RPL WRRSFGR  P SVP  VI  RKLQWRAS
Subjt:  KRTCPLCNAQFDSWFSKIKLSSRSFRKERLPNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESVPTDVIAWRKLQWRAS

Query:  IYDRRIQAIPSSVRSCLVMNLTGSHGVKEAILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAE-----NDFLSPLRPFLYEKTDLF
        IY ++++A+    R  L ++L  +   K  I ERI+PWI+REL+A+LGDPDP++IVH  ++LF+ RLE  +++   +      D +S LR FL +K D+F
Subjt:  IYDRRIQAIPSSVRSCLVMNLTGSHGVKEAILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAE-----NDFLSPLRPFLYEKTDLF

Query:  WHELRYF
        WHELR F
Subjt:  WHELRYF

Sequences

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CDS sequence

Show/hide CDS sequence

mRNA sequence

Show/hide mRNA sequence

ATGCTTGAGGGGAAAATCATGAAGCATTCGGCTGGAGAACCGGCGCGAAAGCTTAACGGCGAAAACTTCGTAGTGAAGCGAACCTGCCCTCTCTGTAACGCTCAATTCGA
TTCATGGTTCTCCAAAATCAAGCTCTCATCGCGAAGCTTCCGGAAAGAAAGATTGCCAAACTTGAATTGTGCCGACAATCTCAAGATTGGAATCGGATCATCCCGGACCG
ACGCTCGCAGGATTCTTCAGAGCACAAGGAATGAATTGAGCAGAGATAGACGGTCGGAGAGACCACTGACATGGCGGCGTTCATTTGGCCGGCGAGGGCCGGAATCTGTA
CCTACTGATGTTATTGCCTGGCGAAAACTTCAATGGCGAGCAAGCATATACGACCGACGTATACAAGCTATCCCATCTTCGGTCAGATCGTGTTTAGTAATGAACTTAAC
AGGAAGTCATGGAGTCAAAGAAGCAATACTAGAAAGGATTAAACCATGGATACAAAGAGAGTTGGAGGCCATCCTTGGAGACCCAGATCCAACTATAATTGTTCATCTGG
TTACCTCACTATTTGTGGCAAGACTTGAAGCTCCTTCCTCACAGCTTAATGCTGAAAATGACTTCCTTTCGCCTTTGCGGCCGTTCCTCTATGAAAAAACTGATTTGTTT
TGGCATGAATTAAGGTACTTTACTCACTGTTCAATATTTCAAATTCTCGTGTTTTTTCCCTGATGCATCTAAATTTTGAAATGAATTTAAGATTTCTGAGTATTGATTTC
TGTTAGCACAATCATAGAAGTAGGATGTATTGAGGGTGTTGTTCACTGCTAGATTCAGTAACAATACCATACACCAGAGAATTGGCGACCAGGAATTACAAGACCATTGT
ATCTTCCCCTGAGTTGAAACCCAGATTTGAAGTAAATTTTCCATATTACTCTCAGTACCTTTTGGTGCTCTTGTCCCATTTGTTCACAATGCCTCTAGCTCGAATGCAAT
AATATAACTAATACCATCTCCTTTCAAGCAACGCCCGAGACTATCCTTGGATATTAATACCCGAGAATTTGCGACCAGGAATTGCATGACCATTGTATCTGCCAGCTGAA
ACCCAGATGAGTTCGAGTAAATTTTCCATATTACTCAATATTTTTTGGTTCCCTTGTCCCATTTGTTCCAAATCCCTCTAGCTCGAATGCAAAAATATAACTAATCCTCA
TCTCCTTTCAAGCAATGTCCCAGACTATCCTTGGCTATTGACTTACTGTATTAACTTGCTCGGAGCAACCCTCTTATATATGGAGTAAGAAAATGCAGGAATGGATTTTG
ATAGAATTCAGAGAAATGAAATGACTTACCAAACAAGAAAATACAGAAGAATGTCGAGTATTTTGAGAATCTCGGACACCTCCCTCTTGAGTGTACTTGAGCACAAACAA
CTAAATTATATCTCGCCTTCATCCCCTCCTACTAGCGAAATTTATGATGGCCACCTGCCTAAGAAATTAAAATATCACGAGTTCCTTTACAACATAATCACGACTGGTTC
ACTCATAAAGCTCCCGCGAGTAGTGTTTGTTTCTTTATCACAATACAAGACTGCATCTTTTATGCTCATCATTTTTCTACTGCCATTTTTATTTAGAAAGTTTTCCTCTC
AGATGTTTTGCAGGAAGTTCATTAC

Protein sequence

Show/hide protein sequence

MLEGKIMKHSAGEPARKLNGENFVVKRTCPLCNAQFDSWFSKIKLSSRSFRKERLPNLNCADNLKIGIGSSRTDARRILQSTRNELSRDRRSERPLTWRRSFGRRGPESV
PTDVIAWRKLQWRASIYDRRIQAIPSSVRSCLVMNLTGSHGVKEAILERIKPWIQRELEAILGDPDPTIIVHLVTSLFVARLEAPSSQLNAENDFLSPLRPFLYEKTDLF
WHELRYFTHCSIFQILVFFP

CmoCh08G011870 (gene) of Cucurbita moschata (Rifu) v1 genome