CuGenDBv2

Gene ID	CmoCh15G003600
Organism	Cucurbita moschata Rifu (Cucurbita moschata (Rifu) v1)
Description	Isocitrate dehydrogenase [NADP]
Genome location	Cmo_Chr15:1689031..1689755
RNA-Seq Expression	CmoCh15G003600
Synteny	CmoCh15G003600
Gene Ontology terms	GO:0006099 - tricarboxylic acid cycle (biological process) GO:0006102 - isocitrate metabolic process (biological process) GO:0006739 - NADP metabolic process (biological process) GO:0005739 - mitochondrion (cellular component) GO:0016021 - integral component of membrane (cellular component) GO:0000287 - magnesium ion binding (molecular function) GO:0004450 - isocitrate dehydrogenase (NADP+) activity (molecular function) GO:0051287 - NAD binding (molecular function)
InterPro domains	IPR004790 - Isocitrate dehydrogenase NADP-dependent IPR024084 - Isopropylmalate dehydrogenase-like domain

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0037553.1 isocitrate dehydrogenase [Cucumis melo var. makuwa]

2.7e-23

90.48

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Query:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI
        GFG+LGLMTSVLLSSDGKTLEAEAAHGTV RHYRLHQKGQETSTNSIASIFAWTRG EH  K+
Subjt:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI

KAG6602427.1 Isocitrate dehydrogenase [NADP], chloroplastic/mitochondrial, partial [Cucurbita argyrosperma subsp. sororia]

2.7e-23

85.07

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Query:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKILQGQ
        GFG+LGLMTSVLLSSDGKTLEAEAAHGTV RHYRLHQKGQETSTNSIASIFAW+RG EH  K+ Q +
Subjt:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKILQGQ

XP_004142794.2 isocitrate dehydrogenase [NADP] [Cucumis sativus]

1.6e-23

89.23

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Query:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKILQ
        GFG+LGLMTSVLLSSDGKTLEAEAAHGTV RHYRLHQKGQETSTNSIASIFAWTRG EH  K+ Q
Subjt:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKILQ

XP_023515364.1 isocitrate dehydrogenase [NADP] [Cucurbita pepo subsp. pepo]

2.7e-23

85.07

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Query:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKILQGQ
        GFG+LGLMTSVLLSSDGKTLEAEAAHGTV RHYRLHQKGQETSTNSIASIFAW+RG EH  K+ Q +
Subjt:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKILQGQ

XP_038890600.1 isocitrate dehydrogenase [NADP] isoform X2 [Benincasa hispida]

2.7e-23

90.48

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Query:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI
        GFG+LGLMTSVLLSSDGKTLEAEAAHGTV RHYRLHQKGQETSTNSIASIFAWTRG EH  K+
Subjt:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KP32 Isocitrate dehydrogenase [NADP]

7.7e-24

89.23

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Query:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKILQ
        GFG+LGLMTSVLLSSDGKTLEAEAAHGTV RHYRLHQKGQETSTNSIASIFAWTRG EH  K+ Q
Subjt:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKILQ

A0A5A7T3K6 Isocitrate dehydrogenase [NADP]

1.3e-23

90.48

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Query:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI
        GFG+LGLMTSVLLSSDGKTLEAEAAHGTV RHYRLHQKGQETSTNSIASIFAWTRG EH  K+
Subjt:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI

A0A6J1HH92 Isocitrate dehydrogenase [NADP]

1.3e-23

85.07

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Query:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKILQGQ
        GFG+LGLMTSVLLSSDGKTLEAEAAHGTV RHYRLHQKGQETSTNSIASIFAW+RG EH  K+ Q +
Subjt:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKILQGQ

A0A6J1JP31 Isocitrate dehydrogenase [NADP]

1.3e-23

85.07

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Query:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKILQGQ
        GFG+LGLMTSVLLSSDGKTLEAEAAHGTV RHYRLHQKGQETSTNSIASIFAW+RG EH  K+ Q +
Subjt:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKILQGQ

A0A803MWP2 Uncharacterized protein

1.3e-23

85.07

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Query:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKILQGQ
        GFG+LGLMTSVLLSSDGKTLEAEAAHGTV RH+RLHQKGQETSTNSIASIFAWTRG EH  K+ + Q
Subjt:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKILQGQ

SwissProt top hits

e value

%identity

Alignment

P50217 Isocitrate dehydrogenase [NADP]

4.0e-22

79.37

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Query:  FPLAGFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEH
        F   GFG+LGLMTSVL+  DGKT+EAEAAHGTV RHYR+HQKG ETSTNSIASIFAWTRG  H
Subjt:  FPLAGFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEH

Q06197 Isocitrate dehydrogenase [NADP]

3.1e-22

74.63

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Query:  FPLAGFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI
        F   GFG+LGLMTSVL+  DGKT+EAEAAHGTV RH+R+HQKG ETSTNSIASIFAWTRG  H  K+
Subjt:  FPLAGFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI

Q40345 Isocitrate dehydrogenase [NADP], chloroplastic (Fragment)

3.1e-22

74.63

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Query:  FPLAGFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI
        F   GFG+LGLMTSVL+  DGKT+EAEAAHGTV RH+R+HQKG ETSTNSIASIFAWTRG  H  K+
Subjt:  FPLAGFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI

Q8LPJ5 Isocitrate dehydrogenase [NADP], chloroplastic/mitochondrial

5.1e-25

85.71

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Query:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI
        GFG+LGLMTSVLLS+DGKTLE+EAAHGTV RH+RLHQKGQETSTNSIASIFAWTRG EH  K+
Subjt:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI

Q9SRZ6 Cytosolic isocitrate dehydrogenase [NADP]

3.1e-22

74.63

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Query:  FPLAGFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI
        F   GFG+LGLMTSVL+  DGKT+EAEAAHGTV RH+R+HQKG ETSTNSIASIFAWTRG  H  K+
Subjt:  FPLAGFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI

Arabidopsis top hits

e value

%identity

Alignment

AT1G54340.1 isocitrate dehydrogenase

8.4e-23

71.64

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Query:  FPLAGFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI
        F   G+G+LG+MTSVL+  DGKT+EAEAAHGTV RHYR+HQKG ETSTNSIASIFAW+RG  H  K+
Subjt:  FPLAGFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI

AT1G65930.1 cytosolic NADP+-dependent isocitrate dehydrogenase

2.2e-23

74.63

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Query:  FPLAGFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI
        F   GFG+LGLMTSVL+  DGKT+EAEAAHGTV RH+R+HQKG ETSTNSIASIFAWTRG  H  K+
Subjt:  FPLAGFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI

AT5G14590.1 Isocitrate/isopropylmalate dehydrogenase family protein

3.6e-26

85.71

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Query:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI
        GFG+LGLMTSVLLS+DGKTLE+EAAHGTV RH+RLHQKGQETSTNSIASIFAWTRG EH  K+
Subjt:  GFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKI

Sequences

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CDS sequence

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ATGATCTCTGTTGTTTTCGTTATGGTTTGCATCGAGTCGAATGCTTATTTTCCATTGGCAGGATTTGGTAATTTGGGGCTAATGACTTCTGTGTTGTTGTCATCTGATGG
GAAGACATTGGAAGCCGAGGCGGCTCATGGCACTGTAATGCGGCATTACCGATTACATCAAAAGGGACAAGAAACCAGTACAAATAGTATTGCCTCTATTTTTGCATGGA
CACGGGGCTTTGAGCATAGTATTAAAATATTGCAGGGCCAAATTAGATAA

mRNA sequence

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Protein sequence

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MISVVFVMVCIESNAYFPLAGFGNLGLMTSVLLSSDGKTLEAEAAHGTVMRHYRLHQKGQETSTNSIASIFAWTRGFEHSIKILQGQIR

CmoCh15G003600 (gene) of Cucurbita moschata (Rifu) v1 genome