CuGenDBv2

Gene ID	CmoCh20G001960
Organism	Cucurbita moschata Rifu (Cucurbita moschata (Rifu) v1)
Description	DNA polymerase epsilon catalytic subunit A-like
Genome location	Cmo_Chr20:963617..965860
RNA-Seq Expression	CmoCh20G001960
Synteny	CmoCh20G001960
Gene Ontology terms	GO:0006260 - DNA replication (biological process) GO:0006281 - DNA repair (biological process) GO:0071897 - DNA biosynthetic process (biological process) GO:0008622 - epsilon DNA polymerase complex (cellular component) GO:0000166 - nucleotide binding (molecular function) GO:0003677 - DNA binding (molecular function) GO:0003887 - DNA-directed DNA polymerase activity (molecular function) GO:0008270 - zinc ion binding (molecular function) GO:0051539 - 4 iron, 4 sulfur cluster binding (molecular function)
InterPro domains	NA

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6570491.1 DNA polymerase epsilon catalytic subunit A, partial [Cucurbita argyrosperma subsp. sororia]

1.6e-18

96.3

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Query:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFAP
        MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKL FDIFSEGDKRLGWL TFAP
Subjt:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFAP

XP_004145799.1 DNA polymerase epsilon catalytic subunit A isoform X1 [Cucumis sativus]

7.4e-16

75.38

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Query:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFAPVLGWQQTAAKI
        MSGESR RGRA+KSSRSKKQR+IRS  EEIESKLGFD+FSEGDKRLGWL TFAP     Q   K+
Subjt:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFAPVLGWQQTAAKI

XP_022943508.1 DNA polymerase epsilon catalytic subunit A-like [Cucurbita moschata]

7.1e-43

100

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Query:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFAPVLGWQQTAAKIGTQRGVASTQWLNERISLARYARTIRKF
        MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFAPVLGWQQTAAKIGTQRGVASTQWLNERISLARYARTIRKF
Subjt:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFAPVLGWQQTAAKIGTQRGVASTQWLNERISLARYARTIRKF

XP_038901114.1 DNA polymerase epsilon catalytic subunit A-like isoform X1 [Benincasa hispida]

4.4e-16

74.63

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Query:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFAPVLGWQQTAAKIGT
        MSGESR RGR DKSSRSKKQRIIRS  EEIESKLGFD+FSEGDKRLGWL TFAP     Q   K+ +
Subjt:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFAPVLGWQQTAAKIGT

XP_038901115.1 DNA polymerase epsilon catalytic subunit A-like isoform X2 [Benincasa hispida]

4.4e-16

74.63

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Query:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFAPVLGWQQTAAKIGT
        MSGESR RGR DKSSRSKKQRIIRS  EEIESKLGFD+FSEGDKRLGWL TFAP     Q   K+ +
Subjt:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFAPVLGWQQTAAKIGT

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KEV5 DNA polymerase epsilon catalytic subunit

3.6e-16

75.38

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Query:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFAPVLGWQQTAAKI
        MSGESR RGRA+KSSRSKKQR+IRS  EEIESKLGFD+FSEGDKRLGWL TFAP     Q   K+
Subjt:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFAPVLGWQQTAAKI

A0A1S3C879 DNA polymerase epsilon catalytic subunit

3.4e-06

87.88

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Query:  VLGWQQTAAKIGTQRGVASTQWLNERISLARYA
        VLGWQQTAAKIG QR  AS+QWLNERISLARYA
Subjt:  VLGWQQTAAKIGTQRGVASTQWLNERISLARYA

A0A1S4E210 DNA polymerase epsilon catalytic subunit

4.0e-15

86.79

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Query:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFA
        MSGESR RGRA+KSSRSKKQR+IRS  EEIESKLGFD+FSEGDKRLGWL TFA
Subjt:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFA

A0A1S4E210 DNA polymerase epsilon catalytic subunit

3.4e-06

87.88

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Query:  VLGWQQTAAKIGTQRGVASTQWLNERISLARYA
        VLGWQQTAAKIG QR  AS+QWLNERISLARYA
Subjt:  VLGWQQTAAKIGTQRGVASTQWLNERISLARYA

A0A1S4E210 DNA polymerase epsilon catalytic subunit

4.0e-15

86.79

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Query:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFA
        MSGESR RGRA+KSSRSKKQR+IRS  EEIESKLGFD+FSEGDKRLGWL TFA
Subjt:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFA

A0A5A7SVB8 DNA polymerase epsilon catalytic subunit

4.0e-15

86.79

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Query:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFA
        MSGESR RGRA+KSSRSKKQR+IRS  EEIESKLGFD+FSEGDKRLGWL TFA
Subjt:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFA

A0A6J1FX14 DNA polymerase epsilon catalytic subunit A-like

3.5e-43

100

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Query:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFAPVLGWQQTAAKIGTQRGVASTQWLNERISLARYARTIRKF
        MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFAPVLGWQQTAAKIGTQRGVASTQWLNERISLARYARTIRKF
Subjt:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFAPVLGWQQTAAKIGTQRGVASTQWLNERISLARYARTIRKF

SwissProt top hits

e value

%identity

Alignment

F4HW04 DNA polymerase epsilon catalytic subunit A

2.3e-07

52.83

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Query:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFA
        MSG++R R R D +  SKK +++ +  +E+ESKLGF +FSEG+ RLGWL TF+
Subjt:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFA

F4IFN6 DNA polymerase epsilon catalytic subunit B

6.8e-04

62.07

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Query:  SPGEEIESKLGFDIFSEGDKRLGWLFTFA
        S  +E+E+KLGF +FS+G+ RLGWL TFA
Subjt:  SPGEEIESKLGFDIFSEGDKRLGWLFTFA

Arabidopsis top hits

e value

%identity

Alignment

AT1G08260.1 DNA polymerase epsilon catalytic subunit

1.6e-08

52.83

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Query:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFA
        MSG++R R R D +  SKK +++ +  +E+ESKLGF +FSEG+ RLGWL TF+
Subjt:  MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFA

AT2G27120.1 DNA polymerase epsilon catalytic subunit

4.8e-05

62.07

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Query:  SPGEEIESKLGFDIFSEGDKRLGWLFTFA
        S  +E+E+KLGF +FS+G+ RLGWL TFA
Subjt:  SPGEEIESKLGFDIFSEGDKRLGWLFTFA

Sequences

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CDS sequence

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ATGAGCGGCGAAAGCCGAGGGCGAGGCCGAGCAGACAAGAGTAGTAGGTCGAAGAAGCAGAGGATAATCCGTTCCCCCGGGGAGGAGATCGAATCAAAGCTTGGATTTGA
TATCTTCTCTGAAGGCGATAAGAGGCTTGGATGGTTGTTCACTTTTGCTCCTGTTCTTGGTTGGCAACAAACAGCTGCAAAGATTGGAACGCAACGCGGTGTTGCATCAA
CCCAATGGTTGAATGAGAGAATCTCTCTTGCAAGATATGCCCGTACCATAAGGAAATTTTGA

mRNA sequence

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Protein sequence

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MSGESRGRGRADKSSRSKKQRIIRSPGEEIESKLGFDIFSEGDKRLGWLFTFAPVLGWQQTAAKIGTQRGVASTQWLNERISLARYARTIRKF

CmoCh20G001960 (gene) of Cucurbita moschata (Rifu) v1 genome