CuGenDBv2

Gene ID	Cp4.1LG12g03280
Organism	Cucurbita pepo var. pepo MU-CU-16 (Cucurbita pepo (MU-CU-16) v4.1)
Description	HYPK_UBA domain-containing protein
Genome location	Cp4.1LG12:2146617..2149254
RNA-Seq Expression	Cp4.1LG12g03280
Synteny	Cp4.1LG12g03280
Gene Ontology terms	GO:0043066 - negative regulation of apoptotic process (biological process) GO:0050821 - protein stabilization (biological process) GO:0110165 - cellular anatomical structure (cellular component)
InterPro domains	IPR038922 - Huntingtin-interacting protein K, UBA-like domain IPR044034 - Nascent polypeptide-associated complex subunit alpha-like, UBA domain

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6575116.1 Huntingtin-interacting protein K, partial [Cucurbita argyrosperma subsp. sororia]

2.62e-63

100

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Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLLR
        AVAAIRYLLR
Subjt:  AVAAIRYLLR

XP_004148802.1 huntingtin-interacting protein K [Cucumis sativus]

1.48e-64

98.18

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Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDG+E LVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLLR
        AVAAIRYLLR
Subjt:  AVAAIRYLLR

XP_008458350.1 PREDICTED: huntingtin-interacting protein K [Cucumis melo]

6.03e-64

98.17

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Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDG+E LVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLL
        AVAAIRYLL
Subjt:  AVAAIRYLL

XP_022958793.1 huntingtin-interacting protein K [Cucurbita moschata]

1.80e-65

100

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Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLLR
        AVAAIRYLLR
Subjt:  AVAAIRYLLR

XP_038906945.1 huntingtin-interacting protein K [Benincasa hispida]

5.29e-64

99.09

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Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDGVE LVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLLR
        AVAAIRYLLR
Subjt:  AVAAIRYLLR

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KI65 HYPK_UBA domain-containing protein

7.17e-65

98.18

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Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDG+E LVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLLR
        AVAAIRYLLR
Subjt:  AVAAIRYLLR

A0A1S3C895 huntingtin-interacting protein K

2.92e-64

98.17

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Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDG+E LVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLL
        AVAAIRYLL
Subjt:  AVAAIRYLL

A0A6J1CC39 huntingtin-interacting protein K

2.40e-63

97.25

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Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        ME GDDGVE LVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAAD+DIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLL
        AVAAIRYLL
Subjt:  AVAAIRYLL

A0A6J1H656 huntingtin-interacting protein K

8.71e-66

100

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Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLLR
        AVAAIRYLLR
Subjt:  AVAAIRYLLR

A0A6J1L4Y3 huntingtin-interacting protein K

8.71e-66

100

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Query:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
        MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD
Subjt:  MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGD

Query:  AVAAIRYLLR
        AVAAIRYLLR
Subjt:  AVAAIRYLLR

SwissProt top hits

e value

%identity

Alignment

Q2PFU1 Huntingtin-interacting protein K

5.4e-08

37.04

Show/hide

Query:  DKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAVAAI
        +++TD  E++++ S+ ++ AM+ I      +  A   REKELA V I   D+++I  E+E+ +  AER+LREH G+ V A+
Subjt:  DKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAVAAI

Q9CR41 Huntingtin-interacting protein K

5.4e-08

37.04

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Query:  DKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAVAAI
        +++TD  E++++ S+ ++ AM+ I      +  A   REKELA V I   D+++I  E+E+ +  AER+LREH G+ V A+
Subjt:  DKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAVAAI

Q9NX55 Huntingtin-interacting protein K

5.4e-08

37.04

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Query:  DKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAVAAI
        +++TD  E++++ S+ ++ AM+ I      +  A   REKELA V I   D+++I  E+E+ +  AER+LREH G+ V A+
Subjt:  DKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAVAAI

Arabidopsis top hits

e value

%identity

Alignment

AT3G06610.1 DNA-binding enhancer protein-related

1.3e-36

78.5

Show/hide

Query:  AGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAV
        A + G E  VDSKD+QQQSKAFDKLTDRVEDRQLDS+RVQ AMASIAAS EAD NA  LREKELA+VKIN ADV+ I NELE++K VAERTLREHKGDAV
Subjt:  AGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAV

Query:  AAIRYLL
        AA R LL
Subjt:  AAIRYLL

Sequences

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CDS sequence

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ATGGAAGCGGGAGACGATGGAGTCGAGAGTCTGGTAGATTCGAAGGATATGCAGCAACAGAGCAAAGCCTTCGATAAGCTCACTGATCGCGTTGAAGACCGGCAACTCGA
TTCCACTCGTGTTCAAGAGGCAATGGCATCTATTGCTGCATCGGCCGAAGCCGATTGGAACGCGATGATGTTGAGAGAGAAGGAGCTTGCTGCTGTCAAAATAAACGCAG
CTGATGTCGACATAATCGCAAACGAACTCGAGTTGGACAAGAAGGTTGCCGAGAGAACCTTGCGCGAGCACAAAGGCGACGCGGTTGCTGCTATACGGTATTTACTACGC
TGA

mRNA sequence

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TTGAGCTAGTTCTACAGTTTGTCTTGAGTTGGGCTTGGGCTTGGGCTCGTTCTACTGTTTGTGCTTTGGGTTGGGCTTGAGCTTGGGCTTGGGCTTCAGCTCGTTTTACT
ATTTGGGCTTAGGTTGGGCTGAAATTTGGGCTTTGTACTTTTATGGACGCCGCTTTTCTCCAACTAACTTTAGTGGGCTTATCGACGTTCGGGCTCATCTGGATCGGGCT
TACGTTTTATTTTTGGGCTTGAAGTTGGGCTTGAAGTAGTAGCGGATCAGTTCTTGTGGGCTTTCTCTAAGAATTGGGCTTTGCGCTCAGGCTCGAGTTGGGCTCTTTAC
TTATTGGGCTTGATTTTGGGGTCGCGCTGAAGACTATTGGGCTTTAATTTGGGCCTGGACGACGCTCTTTGTAGTCTGTCTCAGTGGATTGTCCCATAGTCGTCGAGTTG
GAAATTGTAACCGAGGGTTAGCTGTTCTTAGCTCCTTGCCGTCGCCGATTTGTTACGATTCTCAGTTGCAGCAGGTTCTTCGAGTGTTGCTAAAAATCACAGAAAATACT
GCTACGTTGTGAGTTTGAGAATTCACAGAAAATGGAAGCGGGAGACGATGGAGTCGAGAGTCTGGTAGATTCGAAGGATATGCAGCAACAGAGCAAAGCCTTCGATAAGC
TCACTGATCGCGTTGAAGACCGGCAACTCGATTCCACTCGTGTTCAAGAGGCAATGGCATCTATTGCTGCATCGGCCGAAGCCGATTGGAACGCGATGATGTTGAGAGAG
AAGGAGCTTGCTGCTGTCAAAATAAACGCAGCTGATGTCGACATAATCGCAAACGAACTCGAGTTGGACAAGAAGGTTGCCGAGAGAACCTTGCGCGAGCACAAAGGCGA
CGCGGTTGCTGCTATACGGTATTTACTACGCTGATTCATCAGGTGTTTGAAGAGACTCTGTTTACTTATTACTTGAAGTTTTACTGGGAAAACTATTCTGAAGTGCACAA
GTGAGAATCATAAACATACTTTTTGTGAGTTCAGATTGTATGGAAATGCTGGAAGTTTCTTCTTTTTTCTTCTTTGTAAACCTTAAATATTAGTTCTAAATCTCTTTGCT
GAAGGGGTGATTCGATGAAATTGGCCATGTCTTTAAAGCCATTTGATGATACCCAGATAATCTGTGGTAGGTTGGTGTTTAAAAAGGTTTCAATACGTTCACGGGATTTA
TGCACATACCCCATAAATGGTTCCATCTGAGGTGGAAAAGACCGAAAAGAACCGATGAAACCCGAGTTTAACCTAATTCATAGGGTCATATTTGTAATTTTATTTATTTG
AAATTTGTGTCTATTTGGT

Protein sequence

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MEAGDDGVESLVDSKDMQQQSKAFDKLTDRVEDRQLDSTRVQEAMASIAASAEADWNAMMLREKELAAVKINAADVDIIANELELDKKVAERTLREHKGDAVAAIRYLLR

Cp4.1LG12g03280 (gene) of Cucurbita pepo (MU-CU-16) v4.1 genome