CuGenDBv2

Gene ID	CsGy5G004380
Organism	Cucumis sativus L. var. sativus cv. Gy14 (Cucumber (Gy14) v2.1)
Description	DNA mismatch repair protein MSH4
Genome location	Gy14Chr5:2889998..2890524
RNA-Seq Expression	CsGy5G004380
Synteny	CsGy5G004380
Gene Ontology terms	GO:0006857 - oligopeptide transport (biological process) GO:0007129 - synapsis (biological process) GO:0010777 - meiotic mismatch repair involved in reciprocal meiotic recombination (biological process) GO:0055085 - transmembrane transport (biological process) GO:0000794 - condensed nuclear chromosome (cellular component) GO:0009705 - plant-type vacuole membrane (cellular component) GO:0016021 - integral component of membrane (cellular component) GO:0043073 - germ cell nucleus (cellular component) GO:0005524 - ATP binding (molecular function) GO:0022857 - transmembrane transporter activity (molecular function) GO:0030983 - mismatched DNA binding (molecular function)
InterPro domains	IPR007696 - DNA mismatch repair protein MutS, core IPR036187 - DNA mismatch repair protein MutS, core domain superfamily IPR045076 - DNA mismatch repair MutS family

Homology

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GenBank top hits

e value

%identity

Alignment

XP_008437055.1 PREDICTED: DNA mismatch repair protein MSH4 [Cucumis melo]

3.31e-30

98.39

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Query:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL
        SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLL ANLLQPLKDIETINARLDCL
Subjt:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL

XP_031741354.1 DNA mismatch repair protein MSH4 isoform X1 [Cucumis sativus]

3.31e-30

98.39

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Query:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL
        SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLL ANLLQPLKDIETINARLDCL
Subjt:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL

XP_031741356.1 DNA mismatch repair protein MSH4 isoform X2 [Cucumis sativus]

2.81e-30

98.39

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Query:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL
        SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLL ANLLQPLKDIETINARLDCL
Subjt:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL

XP_031741357.1 DNA mismatch repair protein MSH4 isoform X3 [Cucumis sativus]

2.76e-30

98.39

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Query:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL
        SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLL ANLLQPLKDIETINARLDCL
Subjt:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL

XP_038907063.1 DNA mismatch repair protein MSH4 isoform X2 [Benincasa hispida]

3.32e-30

98.39

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Query:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL
        SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLL ANLLQPLKDIETINARLDCL
Subjt:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KKQ1 MUTSd domain-containing protein

1.15e-36

97.06

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Query:  VQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCLVSIIRAL
        VQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLL ANLLQPLKDIETINARLDCLVSI+RAL
Subjt:  VQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCLVSIIRAL

A0A1S3ATN6 DNA mismatch repair protein MSH4

1.60e-30

98.39

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Query:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL
        SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLL ANLLQPLKDIETINARLDCL
Subjt:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL

A0A438K278 DNA mismatch repair protein MSH4

5.24e-30

90.48

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Query:  GSVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL
        GSVQNLEIIEPLHS+LWGTSNKKRSL++MLKTTKT GG+RLL ANLLQPLKDIETINARLDCL
Subjt:  GSVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL

A0A5A7TER1 DNA mismatch repair protein MSH4

1.60e-30

98.39

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Query:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL
        SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLL ANLLQPLKDIETINARLDCL
Subjt:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL

A0A7J6XDD3 DNA mismatch repair protein MutS

1.37e-29

87.1

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Query:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL
        SVQNLEI+EPLHSNLWG+SNKKRSL++MLKTT+TIGG+RLL ANLLQPLKDIET+NARLDCL
Subjt:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL

SwissProt top hits

e value

%identity

Alignment

B7GW85 DNA mismatch repair protein MutS

4.7e-04

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Query:  QNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCLVSIIR
        +NLEIIEPL  +  GT     SL+ ++   +T  G RLL   L+QP++D   ++ARLD +  +I+
Subjt:  QNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCLVSIIR

B7IBV9 DNA mismatch repair protein MutS

4.7e-04

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Query:  QNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCLVSIIR
        +NLEIIEPL  +  GT     SL+ ++   +T  G RLL   L+QP++D   ++ARLD +  +I+
Subjt:  QNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCLVSIIR

F4JP48 DNA mismatch repair protein MSH4

3.6e-20

77.42

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Query:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL
        SV+NLE+I+P H+ L GTSNKKRSL+ M KTTKT GG+RLL ANLLQPLKDIETIN RLDCL
Subjt:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL

O15457 MutS protein homolog 4

1.3e-06

45.21

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Query:  AELFGGSVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCLVSIIR
        A +   S QNLE+   L +N    +N   +L+ +L  TKT GGSR L +N+L+PL DIETIN RLDC+  +++
Subjt:  AELFGGSVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCLVSIIR

Q99MT2 MutS protein homolog 4

1.7e-06

43.84

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Query:  AELFGGSVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCLVSIIR
        A +   S QNLE+   L +N    SN   +L+ +L  TKT GGSR L +N+L+PL D+ETI+ RLDC+  +++
Subjt:  AELFGGSVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCLVSIIR

Arabidopsis top hits

e value

%identity

Alignment

AT4G17380.1 MUTS-like protein 4

2.5e-21

77.42

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Query:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL
        SV+NLE+I+P H+ L GTSNKKRSL+ M KTTKT GG+RLL ANLLQPLKDIETIN RLDCL
Subjt:  SVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCL

Sequences

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CDS sequence

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ATGACTGCAGATTTCTCATTAAATGCTGAATTGTTTGGTGGCAGCGTTCAGAATTTAGAAATTATCGAGCCACTTCACTCCAATCTTTGGGGAACAAGTAACAAGAAGAG
AAGTCTGTATAACATGCTCAAAACAACAAAAACTATAGGAGGGTCTAGACTTCTTCCTGCCAATCTTTTACAGCCATTAAAAGATATCGAAACCATTAATGCCCGTCTGG
ATTGCTTGGTCAGTATCATACGAGCTTTATGA

mRNA sequence

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Protein sequence

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MTADFSLNAELFGGSVQNLEIIEPLHSNLWGTSNKKRSLYNMLKTTKTIGGSRLLPANLLQPLKDIETINARLDCLVSIIRAL

CsGy5G004380 (gene) of Cucumber (Gy14) v2.1 genome