CuGenDBv2

Gene ID	Cucsat.G1633
Organism	Cucumis sativus L. var. sativus cv. B10 (Cucumber (B10) v3)
Description	E3 ubiquitin-protein ligase RFWD3
Genome location	ctg1000:834458..846113
RNA-Seq Expression	Cucsat.G1633
Synteny	Cucsat.G1633
Gene Ontology terms	GO:0016567 - protein ubiquitination (biological process) GO:0036297 - interstrand cross-link repair (biological process) GO:0005634 - nucleus (cellular component) GO:0005515 - protein binding (molecular function) GO:0046872 - metal ion binding (molecular function) GO:0061630 - ubiquitin protein ligase activity (molecular function)
InterPro domains	NA

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

XP_004143360.1 E3 ubiquitin-protein ligase RFWD3 isoform X1 [Cucumis sativus]

0.0

100

Show/hide

Query:  MPDSDILHVHYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEASSSQN
        MPDSDILHVHYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEASSSQN
Subjt:  MPDSDILHVHYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEASSSQN

Query:  EWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKKEA
        EWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKKEA
Subjt:  EWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKKEA

Query:  NWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELLVDGARLIDVDASNQIVLVAR
        NWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELLVDGARLIDVDASNQIVLVAR
Subjt:  NWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELLVDGARLIDVDASNQIVLVAR

Query:  RGFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLVMFD
        RGFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLVMFD
Subjt:  RGFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLVMFD

Query:  MRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSNDKSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRPKVGMSNEIVYSQPS
        MRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSNDKSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRPKVGMSNEIVYSQPS
Subjt:  MRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSNDKSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRPKVGMSNEIVYSQPS

Query:  PSPSHTAGHRVDGCHVAFKKEDHHQFSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRSVQHLKVHKHPVRDVKYSYGFDGGL
        PSPSHTAGHRVDGCHVAFKKEDHHQFSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRSVQHLKVHKHPVRDVKYSYGFDGGL
Subjt:  PSPSHTAGHRVDGCHVAFKKEDHHQFSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRSVQHLKVHKHPVRDVKYSYGFDGGL

Query:  LGCLSDDILQLFCTKGS
        LGCLSDDILQLFCTKGS
Subjt:  LGCLSDDILQLFCTKGS

XP_008462482.1 PREDICTED: E3 ubiquitin-protein ligase RFWD3 [Cucumis melo]

0.0

94.68

Show/hide

Query:  MPDSDILHVHYEVEDVDDGGGEEEQEQEEEEEE-EETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEASSSQ
        MPDSDILHVHYEVEDVDDGGGEEE+E+EE++++ EETD+SEETVEGHAEE VDYVPEVLQSPRASQTGT GSAQARVSFWVEEE+DKRRRTEGGEASSSQ
Subjt:  MPDSDILHVHYEVEDVDDGGGEEEQEQEEEEEE-EETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEASSSQ

Query:  NEWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKKE
        NEWNR+ENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRK+FAPRIVAADGESQKRIKSLEATCASLEKK+
Subjt:  NEWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKKE

Query:  ANWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELLVDGARLIDVDASNQIVLVA
        ANWC+KEVEWKKRETD+Q KL+ELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFS QVSSCSFILKKEL+VDGARLIDVDASNQIVLVA
Subjt:  ANWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELLVDGARLIDVDASNQIVLVA

Query:  RR--GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLV
        RR  GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLP+AAWSCSWDQNSSHHVYAGLKNGLLV
Subjt:  RR--GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLV

Query:  MFDMRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSNDKSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRPKVGMSNEIVYS
        MFDMRQTVGPLKILQGLTNNPIHTIHSLSS+STVSNDKS+LSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRPKVGMSNEIVYS
Subjt:  MFDMRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSNDKSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRPKVGMSNEIVYS

Query:  QPSPSPSHTAGHRVDGCHVAFKKEDHHQFSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRSVQHLKVHKHPVRDVKYSYGFD
        QPSPSPSHT GHRVDGCHVAFKKEDHHQFSKLGSA+ANIDAIRLPKSTIIDL  CNSLFVSADA+MGDLILQELPSFRSVQHLKVHKHPVRDVKYSYGFD
Subjt:  QPSPSPSHTAGHRVDGCHVAFKKEDHHQFSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRSVQHLKVHKHPVRDVKYSYGFD

Query:  GGLLGCLSDDILQLFCTKGS
         GLL CLSDDIL LFCTKGS
Subjt:  GGLLGCLSDDILQLFCTKGS

XP_022972717.1 E3 ubiquitin-protein ligase RFWD3 isoform X1 [Cucurbita maxima]

0.0

79.41

Show/hide

Query:  MPDS-----DILHV-----HYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRT
        MPDS     DI +V      YEVED DDG      E+EEE+++EETDD EETVEGHAEE  D V E  QSPRASQTG   S QARVSFWVEEE DKRRRT
Subjt:  MPDS-----DILHV-----HYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRT

Query:  EGGEASSSQ----------NEWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGE
        +GGEASSS           NEWNR+E D + C ICM+AWTNYG+HHICCLPCGHLYGMSCINRWLQQR+ AGKCPQCNRKCS KDVRK+FA RIVAAD E
Subjt:  EGGEASSSQ----------NEWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGE

Query:  SQKRIKSLEATCASLEKKEANWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELL
        SQKRI+SLEATCASLE K ANWCKKEVEWKK+ETD+QSK+ EL+ERTNYLEHLLED++RK  +A+LDC F+GKSVS+HNFGLRFSGQVSSC FIL+KELL
Subjt:  SQKRIKSLEATCASLEKKEANWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELL

Query:  VDGARLIDVDASNQIVLVARR--GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCS
        VDGAR IDVD+SNQ+VLVARR  GFGGTHV+TKISLMSPYEREDI IPFCTNAV+DLHISPAARNLVL+SSLGKKLA+LSMESN+IILDYDLPDAAWSCS
Subjt:  VDGARLIDVDASNQIVLVARR--GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCS

Query:  WDQNSSHHVYAGLKNGLLVMFDMRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSND-KSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSR
        WDQNSSH+VYAGLKNG L+MFDMRQTVGPLK LQG+T+NP+HTIHSLS++ T+SND KSVLSASAYG+CQWNFDA EEGPFL+PETNQGVCTSLAYCSSR
Subjt:  WDQNSSHHVYAGLKNGLLVMFDMRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSND-KSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSR

Query:  DELVASYRPKVGMSNEIVYSQPSPSPSHTAGHRVDGCHVAFKKEDHHQ-FSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRS
        DE+VASYRPKVGMS+EI YSQ SPSPSHTAGHRVDGCH+AFKKE++ Q FSKLGSA ANIDAIRLPKST+IDL DC+SLFV  DA+M +LILQELPSFRS
Subjt:  DELVASYRPKVGMSNEIVYSQPSPSPSHTAGHRVDGCHVAFKKEDHHQ-FSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRS

Query:  VQHLKVHKHPVRDVKYSYGFDGGLLGCLSDDILQLFCTKGS
         QHLKVHKHPVRDVKYSYGF  GLL CLSDD LQL CT GS
Subjt:  VQHLKVHKHPVRDVKYSYGFDGGLLGCLSDDILQLFCTKGS

XP_038882129.1 E3 ubiquitin-protein ligase RFWD3 isoform X1 [Benincasa hispida]

0.0

85.44

Show/hide

Query:  MPDS-----DILHVHYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEA
        MPDS     DI+HVHYEVED D+GG EEE +       EETDD EETVE HA EE+DYV E++QSPRASQTG   SAQARVSFWVEEEVDKRRRTEGGEA
Subjt:  MPDS-----DILHVHYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEA

Query:  SSSQNEWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASL
        +SSQNE N    +D  CSICM+ WTNYG+HHICCLPCGHLYGM CINRWL+Q KNAGKCPQCNRKCSTKDVRK+FAPRI AADGESQKRI+SLEATCASL
Subjt:  SSSQNEWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASL

Query:  EKKEANWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELLVDGARLIDVDASNQI
        EKK+A+W KKEVEWKKRETD+Q K+REL+ERTNYLEHLLEDSQRKPVLANLDCTF GKSVSEHNFGLRFSGQV+SCSFILKKELLVDGARLIDVDASNQ+
Subjt:  EKKEANWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELLVDGARLIDVDASNQI

Query:  VLVARR--GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKN
        VLVARR  GFGGTHVLTKISLMSPYEREDI IPFCTNAVRDLHISPA RNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSH++YAGLKN
Subjt:  VLVARR--GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKN

Query:  GLLVMFDMRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSND-KSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRPKVGMSN
        G LVMFDMRQTVGPLK LQGLTNNPIHTIHSLSS+ST+SND KSVLSASAYG+CQWNFDA+ EGPFL+PETNQGVCTSLAYC  RDE+VASYRPKVGMSN
Subjt:  GLLVMFDMRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSND-KSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRPKVGMSN

Query:  EIVYSQPSPSPSHTAGHRVDGCHVAFKKEDH-HQFSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRSVQHLKVHKHPVRDVK
        EIVYSQPSPSPSHTAGH V GCHVAFKKED+  QFSKLGSA+A +DAIRLPKSTIIDL DCNSLFVSADA+MGDLILQELPSFRS+QHLKVHKHPVRDVK
Subjt:  EIVYSQPSPSPSHTAGHRVDGCHVAFKKEDH-HQFSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRSVQHLKVHKHPVRDVK

Query:  YSYGFDGGLLGCLSDDILQLFCTKG
        YS G D GLL CLSDD L LFCTKG
Subjt:  YSYGFDGGLLGCLSDDILQLFCTKG

XP_038882130.1 E3 ubiquitin-protein ligase RFWD3 isoform X2 [Benincasa hispida]

0.0

84.8

Show/hide

Query:  MPDS-----DILHVHYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEA
        MPDS     DI+HVHYEVED D+GG EEE +       EETDD EETVE HA EE+DYV E++QSPRASQTG   SAQARVSFWVEEEVDKRRRTEGGEA
Subjt:  MPDS-----DILHVHYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEA

Query:  SSSQNEWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASL
        +SSQNE N    +D  CSICM+ WTNYG+HHICCLPCGHLYGM CINRWL+Q KNAGKCPQCNRKCSTKDVRK+FAPRI AADGESQKRI+SLEATCASL
Subjt:  SSSQNEWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASL

Query:  EKKEANWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELLVDGARLIDVDASNQI
        EKK+A+W KKEVEWKKRETD+Q K      RTNYLEHLLEDSQRKPVLANLDCTF GKSVSEHNFGLRFSGQV+SCSFILKKELLVDGARLIDVDASNQ+
Subjt:  EKKEANWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELLVDGARLIDVDASNQI

Query:  VLVARR--GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKN
        VLVARR  GFGGTHVLTKISLMSPYEREDI IPFCTNAVRDLHISPA RNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSH++YAGLKN
Subjt:  VLVARR--GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKN

Query:  GLLVMFDMRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSND-KSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRPKVGMSN
        G LVMFDMRQTVGPLK LQGLTNNPIHTIHSLSS+ST+SND KSVLSASAYG+CQWNFDA+ EGPFL+PETNQGVCTSLAYC  RDE+VASYRPKVGMSN
Subjt:  GLLVMFDMRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSND-KSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRPKVGMSN

Query:  EIVYSQPSPSPSHTAGHRVDGCHVAFKKEDH-HQFSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRSVQHLKVHKHPVRDVK
        EIVYSQPSPSPSHTAGH V GCHVAFKKED+  QFSKLGSA+A +DAIRLPKSTIIDL DCNSLFVSADA+MGDLILQELPSFRS+QHLKVHKHPVRDVK
Subjt:  EIVYSQPSPSPSHTAGHRVDGCHVAFKKEDH-HQFSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRSVQHLKVHKHPVRDVK

Query:  YSYGFDGGLLGCLSDDILQLFCTKG
        YS G D GLL CLSDD L LFCTKG
Subjt:  YSYGFDGGLLGCLSDDILQLFCTKG

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KER3 RING-type domain-containing protein

0.0

100

Show/hide

Query:  MPDSDILHVHYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEASSSQN
        MPDSDILHVHYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEASSSQN
Subjt:  MPDSDILHVHYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEASSSQN

Query:  EWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKKEA
        EWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKKEA
Subjt:  EWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKKEA

Query:  NWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELLVDGARLIDVDASNQIVLVAR
        NWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELLVDGARLIDVDASNQIVLVAR
Subjt:  NWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELLVDGARLIDVDASNQIVLVAR

Query:  RGFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLVMFD
        RGFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLVMFD
Subjt:  RGFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLVMFD

Query:  MRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSNDKSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRPKVGMSNEIVYSQPS
        MRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSNDKSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRPKVGMSNEIVYSQPS
Subjt:  MRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSNDKSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRPKVGMSNEIVYSQPS

Query:  PSPSHTAGHRVDGCHVAFKKEDHHQFSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRSVQHLKVHKHPVRDVKYSYGFDGGL
        PSPSHTAGHRVDGCHVAFKKEDHHQFSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRSVQHLKVHKHPVRDVKYSYGFDGGL
Subjt:  PSPSHTAGHRVDGCHVAFKKEDHHQFSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRSVQHLKVHKHPVRDVKYSYGFDGGL

Query:  LGCLSDDILQLFCTKGS
        LGCLSDDILQLFCTKGS
Subjt:  LGCLSDDILQLFCTKGS

A0A1S3CH35 E3 ubiquitin-protein ligase RFWD3

0.0

94.68

Show/hide

Query:  MPDSDILHVHYEVEDVDDGGGEEEQEQEEEEEE-EETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEASSSQ
        MPDSDILHVHYEVEDVDDGGGEEE+E+EE++++ EETD+SEETVEGHAEE VDYVPEVLQSPRASQTGT GSAQARVSFWVEEE+DKRRRTEGGEASSSQ
Subjt:  MPDSDILHVHYEVEDVDDGGGEEEQEQEEEEEE-EETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEASSSQ

Query:  NEWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKKE
        NEWNR+ENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRK+FAPRIVAADGESQKRIKSLEATCASLEKK+
Subjt:  NEWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKKE

Query:  ANWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELLVDGARLIDVDASNQIVLVA
        ANWC+KEVEWKKRETD+Q KL+ELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFS QVSSCSFILKKEL+VDGARLIDVDASNQIVLVA
Subjt:  ANWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELLVDGARLIDVDASNQIVLVA

Query:  RR--GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLV
        RR  GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLP+AAWSCSWDQNSSHHVYAGLKNGLLV
Subjt:  RR--GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLV

Query:  MFDMRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSNDKSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRPKVGMSNEIVYS
        MFDMRQTVGPLKILQGLTNNPIHTIHSLSS+STVSNDKS+LSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRPKVGMSNEIVYS
Subjt:  MFDMRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSNDKSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRPKVGMSNEIVYS

Query:  QPSPSPSHTAGHRVDGCHVAFKKEDHHQFSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRSVQHLKVHKHPVRDVKYSYGFD
        QPSPSPSHT GHRVDGCHVAFKKEDHHQFSKLGSA+ANIDAIRLPKSTIIDL  CNSLFVSADA+MGDLILQELPSFRSVQHLKVHKHPVRDVKYSYGFD
Subjt:  QPSPSPSHTAGHRVDGCHVAFKKEDHHQFSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRSVQHLKVHKHPVRDVKYSYGFD

Query:  GGLLGCLSDDILQLFCTKGS
         GLL CLSDDIL LFCTKGS
Subjt:  GGLLGCLSDDILQLFCTKGS

A0A6J1HDN7 E3 ubiquitin-protein ligase RFWD3 isoform X1

0.0

79.41

Show/hide

Query:  MPDS-----DILHV-----HYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRT
        MPDS     DI +V      YEVED DDG      E+EEE+++EETDD EETVEGHAEE  D V E  QSPRASQTG   S QARVSFWVEEE DKRRRT
Subjt:  MPDS-----DILHV-----HYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRT

Query:  EGGEASSSQ----------NEWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGE
        EGGE SSS           NEWNR+E D + C ICM+AWTNYGEHHICCLPCGHLYGMSCINRWLQQR+ AGKCPQCNRKCS KDVRK+FA RIVAAD E
Subjt:  EGGEASSSQ----------NEWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGE

Query:  SQKRIKSLEATCASLEKKEANWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELL
        SQKRI+SLEATCASLE K ANWCKKEVEWKK+ETD+QSK+ EL+ERTNYLEHLLED++RK  +A+LDC F+GKSVS+HNFGLRFSGQVSSC FIL+KELL
Subjt:  SQKRIKSLEATCASLEKKEANWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELL

Query:  VDGARLIDVDASNQIVLVARR--GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCS
        VDGAR IDVD+SNQ+VLVARR  GFGGTHV+TKISLMSPYEREDI IPFCTNAV+DLHISPAAR LVL+SSLGKKLA+LSMESN+IILDYDLPDAAWSCS
Subjt:  VDGARLIDVDASNQIVLVARR--GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCS

Query:  WDQNSSHHVYAGLKNGLLVMFDMRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSND-KSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSR
        WDQNSSH+VYAGLKNG L+MFDMRQTVGPLK L+G+T+NP+HTIHSLS++ T+SND KSVLSASAYG+CQWNFDA EEGPFL+PETNQGVCTSLAYCSSR
Subjt:  WDQNSSHHVYAGLKNGLLVMFDMRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSND-KSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSR

Query:  DELVASYRPKVGMSNEIVYSQPSPSPSHTAGHRVDGCHVAFKKEDHHQ-FSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRS
        DE+VASYRPKVGM +EI YSQ SPSPSHTAGHRVDGCH+AFKKE++ Q FSKLGSA ANIDAIRLPKSTIIDL DC+SLFV  DA+M +LILQELPSFRS
Subjt:  DELVASYRPKVGMSNEIVYSQPSPSPSHTAGHRVDGCHVAFKKEDHHQ-FSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRS

Query:  VQHLKVHKHPVRDVKYSYGFDGGLLGCLSDDILQLFCTKGS
         QHLKVHKHPVRDVKYSYGF  GLL CLSDD LQL CTKGS
Subjt:  VQHLKVHKHPVRDVKYSYGFDGGLLGCLSDDILQLFCTKGS

A0A6J1I5M2 E3 ubiquitin-protein ligase RFWD3 isoform X1

0.0

79.41

Show/hide

Query:  MPDS-----DILHV-----HYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRT
        MPDS     DI +V      YEVED DDG      E+EEE+++EETDD EETVEGHAEE  D V E  QSPRASQTG   S QARVSFWVEEE DKRRRT
Subjt:  MPDS-----DILHV-----HYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRT

Query:  EGGEASSSQ----------NEWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGE
        +GGEASSS           NEWNR+E D + C ICM+AWTNYG+HHICCLPCGHLYGMSCINRWLQQR+ AGKCPQCNRKCS KDVRK+FA RIVAAD E
Subjt:  EGGEASSSQ----------NEWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGE

Query:  SQKRIKSLEATCASLEKKEANWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELL
        SQKRI+SLEATCASLE K ANWCKKEVEWKK+ETD+QSK+ EL+ERTNYLEHLLED++RK  +A+LDC F+GKSVS+HNFGLRFSGQVSSC FIL+KELL
Subjt:  SQKRIKSLEATCASLEKKEANWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELL

Query:  VDGARLIDVDASNQIVLVARR--GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCS
        VDGAR IDVD+SNQ+VLVARR  GFGGTHV+TKISLMSPYEREDI IPFCTNAV+DLHISPAARNLVL+SSLGKKLA+LSMESN+IILDYDLPDAAWSCS
Subjt:  VDGARLIDVDASNQIVLVARR--GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCS

Query:  WDQNSSHHVYAGLKNGLLVMFDMRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSND-KSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSR
        WDQNSSH+VYAGLKNG L+MFDMRQTVGPLK LQG+T+NP+HTIHSLS++ T+SND KSVLSASAYG+CQWNFDA EEGPFL+PETNQGVCTSLAYCSSR
Subjt:  WDQNSSHHVYAGLKNGLLVMFDMRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSND-KSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSR

Query:  DELVASYRPKVGMSNEIVYSQPSPSPSHTAGHRVDGCHVAFKKEDHHQ-FSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRS
        DE+VASYRPKVGMS+EI YSQ SPSPSHTAGHRVDGCH+AFKKE++ Q FSKLGSA ANIDAIRLPKST+IDL DC+SLFV  DA+M +LILQELPSFRS
Subjt:  DELVASYRPKVGMSNEIVYSQPSPSPSHTAGHRVDGCHVAFKKEDHHQ-FSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRS

Query:  VQHLKVHKHPVRDVKYSYGFDGGLLGCLSDDILQLFCTKGS
         QHLKVHKHPVRDVKYSYGF  GLL CLSDD LQL CT GS
Subjt:  VQHLKVHKHPVRDVKYSYGFDGGLLGCLSDDILQLFCTKGS

A0A6J1IAX3 E3 ubiquitin-protein ligase RFWD3 isoform X2

0.0

76.29

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Query:  MPDS-----DILHV-----HYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRT
        MPDS     DI +V      YEVED DDG      E+EEE+++EETDD EETVEGHAEE  D V E  QSPRASQTG   S QARVSFWVEEE DKRRRT
Subjt:  MPDS-----DILHV-----HYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRT

Query:  EGGEASSSQ----------NEWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGE
        +GGEASSS           NEWNR+E D + C ICM+AWTNYG+HHICCLPCGHLYGMSCINRWLQQR+ AGKCPQCNRKCS KDVRK+FA RIVAAD E
Subjt:  EGGEASSSQ----------NEWNRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGE

Query:  SQKRIKSLEATCASLEKKEANWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELL
        SQKRI+SLEATCASLE K ANWCKKEVEWKK+ETD+QSK+ EL+ERTNYLEHLLED++RK  +A+LDC F+GKSVS+HNFGLRFSGQVSSC FIL+KELL
Subjt:  SQKRIKSLEATCASLEKKEANWCKKEVEWKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELL

Query:  VDGARLIDVDASNQIVLVARR--GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCS
        VDGAR IDVD+SNQ+VLVARR  GFGGTHV+TK                      DLHISPAARNLVL+SSLGKKLA+LSMESN+IILDYDLPDAAWSCS
Subjt:  VDGARLIDVDASNQIVLVARR--GFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCS

Query:  WDQNSSHHVYAGLKNGLLVMFDMRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSND-KSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSR
        WDQNSSH+VYAGLKNG L+MFDMRQTVGPLK LQG+T+NP+HTIHSLS++ T+SND KSVLSASAYG+CQWNFDA EEGPFL+PETNQGVCTSLAYCSSR
Subjt:  WDQNSSHHVYAGLKNGLLVMFDMRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSND-KSVLSASAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSR

Query:  DELVASYRPKVGMSNEIVYSQPSPSPSHTAGHRVDGCHVAFKKEDHHQ-FSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRS
        DE+VASYRPKVGMS+EI YSQ SPSPSHTAGHRVDGCH+AFKKE++ Q FSKLGSA ANIDAIRLPKST+IDL DC+SLFV  DA+M +LILQELPSFRS
Subjt:  DELVASYRPKVGMSNEIVYSQPSPSPSHTAGHRVDGCHVAFKKEDHHQ-FSKLGSAHANIDAIRLPKSTIIDLPDCNSLFVSADAIMGDLILQELPSFRS

Query:  VQHLKVHKHPVRDVKYSYGFDGGLLGCLSDDILQLFCTKGS
         QHLKVHKHPVRDVKYSYGF  GLL CLSDD LQL CT GS
Subjt:  VQHLKVHKHPVRDVKYSYGFDGGLLGCLSDDILQLFCTKGS

SwissProt top hits

e value

%identity

Alignment

D2HWM5 E3 ubiquitin-protein ligase RFWD3

3.7e-29

Show/hide

Query:  NRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKK---E
        ++ + +   C+IC + WTN G+H +  L CGHL+G  CI++WL  +  A KCPQCN+K    D+  ++A  + A D    +R+KS       L K+   E
Subjt:  NRSENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKK---E

Query:  ANWCKKEVEWKKRE-TDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFS-GQVSSCSFILKKELLVDGARLIDVDASNQIVL
        +  C+ +++    E + + S++++L + T      +  S       +L+C    ++  +++F   F+     +C  +   + L   + L+    S Q   
Subjt:  ANWCKKEVEWKKRE-TDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFS-GQVSSCSFILKKELLVDGARLIDVDASNQIVL

Query:  VARRGFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLV
        +   GFG   + T     S Y      +P     +R L  S  ++ L+L +SL   + + S+E+N ++  Y+     WSC W  + S+H+YAGL NG ++
Subjt:  VARRGFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLV

Query:  MFDMRQTVGPL-KILQGLTNNPIHTIHSL-SSHSTVSNDKSVLSASAYGICQWNFD-ALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRP
        ++D+R T   + +++      P+ ++  +  + S       VL+ +      W         P ++P    G C      SS    + +YRP
Subjt:  MFDMRQTVGPL-KILQGLTNNPIHTIHSL-SSHSTVSNDKSVLSASAYGICQWNFD-ALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRP

Q6PCD5 E3 ubiquitin-protein ligase RFWD3

1.8e-28

28.76

Show/hide

Query:  ENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKK---EANW
        E +   C+IC++ WTN G+H +  L CGHL+G  CI+ WL  +    KCPQCN+K    D+  ++A  + A D   Q+R+KS       L K+   E+  
Subjt:  ENDDMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKK---EANW

Query:  CKKEVE-WKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDC--TFQGKSVSEHNFGLRFS-GQVSSCSFILKKELLVDGARLIDVDASNQIVLV
        C+ +++    + T +Q ++++L + T++    L+  +       L C  + QG+   +++F   F+  Q  +C  +   + L   + L+    S Q   +
Subjt:  CKKEVE-WKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDC--TFQGKSVSEHNFGLRFS-GQVSSCSFILKKELLVDGARLIDVDASNQIVLV

Query:  ARRGFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLVM
           GFG   + T     S Y      IP     +R L  S   R L+L +SL   + + S+E+N ++  Y+     WSC W  + ++++YAGL NG +++
Subjt:  ARRGFGGTHVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLVM

Query:  FDMRQT
        +D+R T
Subjt:  FDMRQT

Q8CIK8 E3 ubiquitin-protein ligase RFWD3

5.1e-23

25.85

Show/hide

Query:  EEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEASSSQNEWNRSENDDMICSICMDAWTNYGEHHIC
        + E       ++   +G AE+E   V          + G   + Q   S   ++ V K    +    S+ ++E      +   C+IC++ WTN G+H I 
Subjt:  EEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEASSSQNEWNRSENDDMICSICMDAWTNYGEHHIC

Query:  CLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKK---EANWCKKEVE-WKKRETDMQSKLRELS
         L CGHL+G  CI++WL+ +    KCPQCN+K    D+  I+A  + A D   Q+R+KS       L K+   E+  C+ +++    + T + S++++L 
Subjt:  CLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKK---EANWCKKEVE-WKKRETDMQSKLRELS

Query:  E-RTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFS-GQVSSCSFILKKELLVDG-ARLIDVDASNQIVLVARRGFGGTHVLTKISLMSPYERE
        +    +     +   R   L    C    +S  +++    F+  Q   C  +       DG + L+    S Q   +   GFG   + T     S Y   
Subjt:  E-RTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFS-GQVSSCSFILKKELLVDG-ARLIDVDASNQIVLVARRGFGGTHVLTKISLMSPYERE

Query:  DIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLVMFDMRQT
           IP     +R L  S  ++ L+L +SL   + + S+E+N ++  Y+     WSC W  + +++VYAGL +G ++++D+R T
Subjt:  DIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLVMFDMRQT

Arabidopsis top hits

e value

%identity

Alignment

AT5G03450.1 Transducin/WD40 repeat-like superfamily protein

6.4e-138

44.7

Show/hide

Query:  GEEEQEQEEEEEE--------EETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEASSSQN----EWNRSEND
        GEEE E+EE+EEE        +E D+ EE  E    +  +Y+ +VL SP             RVS    E ++ + R++G  +SSS +    EW + + +
Subjt:  GEEEQEQEEEEEE--------EETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEASSSQN----EWNRSEND

Query:  DMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKKEANWCKKEVE
         + CSICM+ WT+ G+H +CCLPCGHLYG SCIN+W QQR++ GKCP CN+ CS +DVRKI+A R+ A D E+ KRI  LEA   S+E+K A+W  KEV+
Subjt:  DMICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKKEANWCKKEVE

Query:  WKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELLVDGARLIDVDASNQIVLVARR--GFGGT
        WK  E +++ ++ +L ++   +E   + SQ +  +A+     Q K +  HN      GQ  SCSF  + +LL++G R+ D+D   QI+L ARR  G GGT
Subjt:  WKKRETDMQSKLRELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELLVDGARLIDVDASNQIVLVARR--GFGGT

Query:  HVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLVMFDMRQTVG
         VLT++SL SP E +DI +P  T A++DLH+SP    L +F SLGKKL+++S+ES++ +L YDLP A WSCSWD  SSHH+YAGL+NG++++FDMRQT G
Subjt:  HVLTKISLMSPYEREDIGIPFCTNAVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLVMFDMRQTVG

Query:  PLKILQGLTNNPIHTIHSLSSHSTVSND-KSVLSASAYGICQWNFDALEEGPFLIPET-NQGVCTSLAYCSSRDELVASYRPKVGMSNEIVYSQPS---P
        P   + GLT NP+HT+H LS +ST ++D +++LSAS+ G+CQWN    E  P L+ ET N GVC S +YC   + +VASYRP+VG S++ V +QPS    
Subjt:  PLKILQGLTNNPIHTIHSLSSHSTVSND-KSVLSASAYGICQWNFDALEEGPFLIPET-NQGVCTSLAYCSSRDELVASYRPKVGMSNEIVYSQPS---P

Query:  SPSHTAGHRVDGCHVAFKKED-HHQFSKLGSAHANIDAIRLPKSTIIDL-PDCNSLFVSADAIMGDLILQELPSFRSVQHLKVHKH-PVRDVKYSYGFDG
          S++  + VDG HV  K+      + KL S  A +D IRLP++ IID   +   LF S D    +LILQ+  +F   Q L +  H P++DVKY +    
Subjt:  SPSHTAGHRVDGCHVAFKKED-HHQFSKLGSAHANIDAIRLPKSTIIDL-PDCNSLFVSADAIMGDLILQELPSFRSVQHLKVHKH-PVRDVKYSYGFDG

Query:  GLLGCLSDDILQL
         LLG L+DD LQ+
Subjt:  GLLGCLSDDILQL

AT5G03750.1 BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT5G03450.1)

5.1e-10

55.32

Show/hide

Query:  SCSWDQNSSHHVYAGLKNGLLVMFDMRQTVGPLKILQGLTNNPIHTI
        SCSWD N+ H+VYAGL+NG++++FDMRQ  GPL  L  +T+N +H +
Subjt:  SCSWDQNSSHHVYAGLKNGLLVMFDMRQTVGPLKILQGLTNNPIHTI

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGCCGGACTCCGACATTCTGCATGTTCATTACGAAGTCGAAGATGTTGACGACGGGGGAGGAGAAGAAGAACAAGAACAAGAAGAAGAAGAAGAAGAAGAGGAGACTGA
CGACAGTGAGGAAACAGTAGAAGGGCACGCGGAAGAAGAAGTTGATTATGTTCCTGAGGTGTTGCAATCGCCTAGGGCTTCACAAACGGGTACTCCTGGATCTGCTCAAG
CTAGGGTTTCGTTTTGGGTCGAGGAAGAGGTAGACAAGCGGAGAAGGACCGAGGGAGGTGAAGCGAGTTCTTCGCAGAATGAATGGAATCGGAGTGAAAATGATGACATG
ATTTGCTCTATTTGCATGGATGCGTGGACCAATTACGGTGAACATCATATTTGTTGTCTTCCTTGTGGGCACTTGTATGGCATGTCTTGTATCAATAGATGGTTGCAACA
ACGTAAAAATGCAGGGAAGTGTCCACAGTGTAATAGAAAGTGTTCCACGAAGGATGTCAGGAAAATTTTTGCACCACGAATTGTTGCTGCTGATGGAGAATCTCAAAAGA
GAATCAAGTCACTTGAAGCTACTTGTGCCTCTCTTGAGAAGAAGGAGGCAAATTGGTGTAAGAAAGAAGTTGAATGGAAAAAGAGAGAAACAGATATGCAATCTAAACTT
CGAGAACTTTCTGAGAGGACAAATTATTTGGAGCATTTATTAGAAGATTCACAGAGAAAACCTGTGCTAGCCAATCTTGATTGCACCTTTCAGGGGAAATCTGTATCTGA
GCATAACTTTGGCTTAAGGTTTAGCGGCCAGGTTTCTTCTTGCAGTTTCATATTAAAGAAAGAGCTTCTGGTGGATGGTGCACGATTGATCGATGTAGATGCCTCTAACC
AAATTGTTTTGGTTGCAAGAAGGGGTTTTGGTGGGACACATGTACTTACTAAGATAAGCTTAATGTCTCCATATGAAAGGGAAGATATAGGAATTCCCTTTTGTACTAAT
GCTGTAAGGGACTTGCATATTTCTCCGGCTGCTAGAAACCTTGTGCTTTTTTCTTCATTAGGGAAGAAATTAGCTATACTCAGTATGGAAAGCAACCATATCATCCTTGA
CTATGATTTACCGGATGCTGCTTGGTCGTGTTCATGGGATCAGAATAGTTCACACCATGTTTATGCTGGATTGAAGAATGGATTGCTGGTGATGTTTGATATGCGACAAA
CTGTGGGTCCCCTGAAAATCTTGCAAGGGTTGACAAACAATCCAATCCATACAATACATTCTCTTTCAAGTCACTCAACTGTTTCTAATGATAAATCTGTTTTATCTGCT
TCTGCATATGGCATATGTCAATGGAACTTTGATGCATTAGAAGAAGGGCCGTTTTTGATTCCAGAAACAAATCAAGGAGTTTGTACGTCTCTTGCCTATTGCTCAAGTAG
AGACGAACTTGTTGCTTCGTACCGTCCCAAAGTTGGAATGTCCAATGAGATAGTTTATTCTCAGCCTTCACCTTCCCCTTCTCATACTGCTGGACATAGAGTTGATGGCT
GCCACGTGGCATTTAAGAAAGAAGACCATCACCAATTTTCAAAGTTGGGTTCAGCACATGCCAATATAGACGCGATACGCTTGCCGAAGTCTACCATCATAGATCTCCCA
GACTGCAATAGCTTGTTTGTATCCGCAGATGCAATAATGGGTGACTTGATCTTGCAAGAACTGCCTTCTTTTAGGTCTGTTCAGCATCTTAAAGTGCATAAGCATCCTGT
TCGTGATGTGAAGTATTCGTATGGCTTCGATGGAGGATTGCTTGGTTGTTTAAGTGATGATATCCTTCAACTTTTCTGCACGAAAGGCTCATGA

mRNA sequence

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Protein sequence

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MPDSDILHVHYEVEDVDDGGGEEEQEQEEEEEEEETDDSEETVEGHAEEEVDYVPEVLQSPRASQTGTPGSAQARVSFWVEEEVDKRRRTEGGEASSSQNEWNRSENDDM
ICSICMDAWTNYGEHHICCLPCGHLYGMSCINRWLQQRKNAGKCPQCNRKCSTKDVRKIFAPRIVAADGESQKRIKSLEATCASLEKKEANWCKKEVEWKKRETDMQSKL
RELSERTNYLEHLLEDSQRKPVLANLDCTFQGKSVSEHNFGLRFSGQVSSCSFILKKELLVDGARLIDVDASNQIVLVARRGFGGTHVLTKISLMSPYEREDIGIPFCTN
AVRDLHISPAARNLVLFSSLGKKLAILSMESNHIILDYDLPDAAWSCSWDQNSSHHVYAGLKNGLLVMFDMRQTVGPLKILQGLTNNPIHTIHSLSSHSTVSNDKSVLSA
SAYGICQWNFDALEEGPFLIPETNQGVCTSLAYCSSRDELVASYRPKVGMSNEIVYSQPSPSPSHTAGHRVDGCHVAFKKEDHHQFSKLGSAHANIDAIRLPKSTIIDLP
DCNSLFVSADAIMGDLILQELPSFRSVQHLKVHKHPVRDVKYSYGFDGGLLGCLSDDILQLFCTKGS

Cucsat.G1633 (gene) of Cucumber (B10) v3 genome