CuGenDBv2

Gene ID	Cucsat.G6193
Organism	Cucumis sativus L. var. sativus cv. B10 (Cucumber (B10) v3)
Description	Hypoxanthine phosphoribosyltransferase
Genome location	ctg1425:1010563..1012978
RNA-Seq Expression	Cucsat.G6193
Synteny	Cucsat.G6193
Gene Ontology terms	GO:0006166 - purine ribonucleoside salvage (biological process) GO:0006178 - guanine salvage (biological process) GO:0009845 - seed germination (biological process) GO:0032263 - GMP salvage (biological process) GO:0032264 - IMP salvage (biological process) GO:0046100 - hypoxanthine metabolic process (biological process) GO:0005737 - cytoplasm (cellular component) GO:0016021 - integral component of membrane (cellular component) GO:0000166 - nucleotide binding (molecular function) GO:0000287 - magnesium ion binding (molecular function) GO:0004422 - hypoxanthine phosphoribosyltransferase activity (molecular function) GO:0052657 - guanine phosphoribosyltransferase activity (molecular function)
InterPro domains	IPR000836 - Phosphoribosyltransferase domain IPR005904 - Hypoxanthine phosphoribosyl transferase IPR029057 - Phosphoribosyltransferase-like

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0031631.1 hypoxanthine-guanine phosphoribosyltransferase [Cucumis melo var. makuwa]

8.19e-100

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Query:  PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR
        PPV VGVATGAFIFLADLVR INIPIAVDFVRVESYGFGT SNG+PTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR
Subjt:  PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR

Query:  RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK
        RQVNF LVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECY+
Subjt:  RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK

XP_004140948.1 uncharacterized protein LOC101219321 isoform X1 [Cucumis sativus]

4.46e-104

99.33

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Query:  PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR
        PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNG+PTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR
Subjt:  PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR

Query:  RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK
        RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK
Subjt:  RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK

XP_008456720.1 PREDICTED: hypoxanthine-guanine phosphoribosyltransferase [Cucumis melo]

1.58e-99

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Query:  PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR
        PPV VGVATGAFIFLADLVR INIPIAVDFVRVESYGFGT SNG+PTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR
Subjt:  PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR

Query:  RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK
        RQVNF LVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECY+
Subjt:  RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK

XP_023527455.1 uncharacterized protein LOC111790677 [Cucurbita pepo subsp. pepo]

2.89e-93

85.16

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Query:  TEPLPPPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFL
        +E   PPV VGVATGAFIFLADLVRRIN+PI +DFVRVESYG GT+SNG+P ISSDLKVDVKNKHVILVEDIVD+GNTLSCL+AHME KGASSVSVCTFL
Subjt:  TEPLPPPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFL

Query:  DKPTRRQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK
        DKPTRR+V+F LVGEGKFY GF+CPDYFVVGYGMDFAELYRNLPY+G+LKPECY+
Subjt:  DKPTRRQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK

XP_038885606.1 hypoxanthine-guanine phosphoribosyltransferase [Benincasa hispida]

5.25e-96

90.67

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Query:  PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR
        PPV VGVATG+FIFLADLVRRIN+P+AVDFVRVESYGFGTQSNG+P ISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHME KGASSVSVCTFLDKP R
Subjt:  PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR

Query:  RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK
        R+VNF LVGEGKFY GF+CPDYFVVGYGMDFAELYRNLPYVG+LKPECY+
Subjt:  RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK

TrEMBL top hits

e value

%identity

Alignment

A0A0A0K9G9 Hypoxanthine phosphoribosyltransferase

2.16e-104

99.33

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Query:  PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR
        PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNG+PTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR
Subjt:  PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR

Query:  RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK
        RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK
Subjt:  RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK

A0A1S3C3Z8 Hypoxanthine phosphoribosyltransferase

7.64e-100

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Query:  PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR
        PPV VGVATGAFIFLADLVR INIPIAVDFVRVESYGFGT SNG+PTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR
Subjt:  PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR

Query:  RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK
        RQVNF LVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECY+
Subjt:  RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK

A0A5A7SQ16 Hypoxanthine phosphoribosyltransferase

3.97e-100

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Query:  PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR
        PPV VGVATGAFIFLADLVR INIPIAVDFVRVESYGFGT SNG+PTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR
Subjt:  PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR

Query:  RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK
        RQVNF LVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECY+
Subjt:  RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK

A0A6J1BZ71 Hypoxanthine phosphoribosyltransferase

4.00e-93

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Query:  PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR
        PPV VGVATGAF+FLADLVR IN+PI+VD VRVESYGFGT SNG+P ISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHME KGASSVSVCTFLDKPTR
Subjt:  PPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTR

Query:  RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK
        R+V+F LVGEGKFY GF+CPDYFVVGYGMDFAE YRNLPYVG+LKPECY+
Subjt:  RQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK

A0A6J1JQ71 Hypoxanthine phosphoribosyltransferase

5.68e-93

84.52

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Query:  TEPLPPPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFL
        +E   PPV VGVATGAFIFLADLVRRIN+PI +DFVRVESYG GT+SNG+P ISSDLKVDVKNKHVILVEDIVD+GNTLSCL+AHME KGAS+VSVCTFL
Subjt:  TEPLPPPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFL

Query:  DKPTRRQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK
        DKPTRR+V+F LVGEGKFY GF+CPDYFVVGYGMDFAELYRNLPY+G+LKPECY+
Subjt:  DKPTRRQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK

SwissProt top hits

e value

%identity

Alignment

P45078 Hypoxanthine phosphoribosyltransferase

3.5e-32

45.71

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Query:  VFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTRRQ
        V VG+  G+F+F+AD+VR+IN+P+ ++F+   SYG G  +N    I+ DL  D+K KHV++VEDI+DTG TL  +   + ++  +S+++CT LDKP+RR+
Subjt:  VFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTRRQ

Query:  VNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVG
        V  P+      + GF+ PD FVVGYG+D+A+ +RNL Y+G
Subjt:  VNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVG

Q724J4 Bifunctional protein TilS/HprT

1.0e-31

47.3

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Query:  PVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTRR
        P+ VGV  GA  F+ DL++R++  + +DF+ V SYG GT S+G   I  DL   V+ + V+++EDI+D+G TLS L+  ++ + A SV + T LDKP  R
Subjt:  PVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTRR

Query:  QVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECY
         V          Y GF  P+ FVVGYG+D+AE YRNLPY+GILKPE Y
Subjt:  QVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECY

Q839B2 Hypoxanthine-guanine phosphoribosyltransferase

7.0e-33

46.98

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Query:  PVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTRR
        P+ VG+  GA  F+ADL R IN  + +DF+ V SYG  T S+G   I  DL  +V+ +H+++VEDI+D+G TL+ L+     + A+SV + T LDKP  R
Subjt:  PVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTRR

Query:  QVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK
         V+         Y GF  P+ FVVGYG+D+AE YRNLPY+G+LKPE Y+
Subjt:  QVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK

Q8YAC7 Bifunctional protein TilS/HprT

1.0e-31

47.3

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Query:  PVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTRR
        P+ VGV  GA  F+ DL++R++  + +DF+ V SYG GT S+G   I  DL   V+ + V+++EDI+D+G TLS L+  ++ + A SV + T LDKP  R
Subjt:  PVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTRR

Query:  QVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECY
         V          Y GF  P+ FVVGYG+D+AE YRNLPY+GILKPE Y
Subjt:  QVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECY

Q92F56 Bifunctional protein TilS/HprT

1.0e-31

47.97

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Query:  PVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTRR
        P+ VGV  GA  F+ DL++RI+  + +DF+ V SYG GT S+G   I  DL   V+ + V+++EDI+D+G TLS L+  ++ + A SV + T LDKP  R
Subjt:  PVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTRR

Query:  QVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECY
         V          Y GF  P+ FVVGYG+D+AE YRNLPY+GILKPE Y
Subjt:  QVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECY

Arabidopsis top hits

e value

%identity

Alignment

AT1G71750.1 Hypoxanthine-guanine phosphoribosyltransferase

1.8e-63

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Query:  PVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTRR
        P+FVGVATGA +FLADLVRRI++PIA+DF+R ESYG GT S+G P +S DLK+D+ NKHV+LVEDIVDTGNTLSCLI HM+ K ASSVSVCT LDKP+RR
Subjt:  PVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTRR

Query:  QVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECY
        +V++ LVG+GKFYSGF+CPD FVVGYGMDFAE YRNL Y+G+LKPE Y
Subjt:  QVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECY

AT1G71750.2 Hypoxanthine-guanine phosphoribosyltransferase

4.8e-61

70.25

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Query:  PVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTRR
        P+FVGVATGA +FLADLVRRI++PIA+DF+R ESYG GT S+G P +S DLK+D+ NKHV+LVEDIVDTGNTLSCLI HM+ K ASSVSVCT LDKP+RR
Subjt:  PVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSDLKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTRR

Query:  QVNFPLVGEGKFYSGFQ----------CPDYFVVGYGMDFAELYRNLPYVGILKPECY
        +V++ LVG+GKFYSGF+          CPD FVVGYGMDFAE YRNL Y+G+LKPE Y
Subjt:  QVNFPLVGEGKFYSGFQ----------CPDYFVVGYGMDFAELYRNLPYVGILKPECY

Sequences

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CDS sequence

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ATGGTAAGAAGAGAGCATATCGAATTCATAGTCACTTGGCCGGTCGTCCCAACCTACCATCGTCCATGGCACTTCACTCTCACATTGAGAGAGTGCTCTGGACCCATGAC
CAAATTTCGGCTCGAGTCTCTGACCTTGCCTCCCAAATCTCCATCGCCTTTGACGGAGCCTCTTCCCCCCCCAGTCTTTGTCGGCGTCGCCACCGGAGCCTTCATTTTCC
TCGCCGACTTGGTCCGCCGCATCAACATTCCAATCGCTGTTGACTTCGTTCGTGTCGAATCTTACGGTTTCGGTACTCAGTCTAATGGTTCTCCTACAATCTCATCGGAC
TTGAAGGTCGATGTTAAGAACAAGCATGTAATTCTGGTCGAGGATATTGTAGATACTGGGAATACTTTATCATGTCTCATTGCTCACATGGAGGTAAAAGGAGCATCATC
TGTATCAGTATGCACTTTTCTTGATAAACCAACAAGACGACAAGTTAATTTTCCGTTAGTAGGCGAAGGAAAGTTCTACTCCGGATTCCAATGTCCAGATTATTTTGTGG
TCGGGTATGGAATGGACTTTGCGGAGCTGTACAGAAATTTACCATATGTTGGCATTTTGAAACCTGAATGTTACAAGTGA

mRNA sequence

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Protein sequence

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MVRREHIEFIVTWPVVPTYHRPWHFTLTLRECSGPMTKFRLESLTLPPKSPSPLTEPLPPPVFVGVATGAFIFLADLVRRINIPIAVDFVRVESYGFGTQSNGSPTISSD
LKVDVKNKHVILVEDIVDTGNTLSCLIAHMEVKGASSVSVCTFLDKPTRRQVNFPLVGEGKFYSGFQCPDYFVVGYGMDFAELYRNLPYVGILKPECYK

Cucsat.G6193 (gene) of Cucumber (B10) v3 genome