CuGenDBv2

Gene ID	HG10001210
Organism	Lagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
Description	protein N-lysine methyltransferase METTL21A
Genome location	Chr09:14983154..14987675
RNA-Seq Expression	HG10001210
Synteny	HG10001210
Gene Ontology terms	GO:0006479 - protein methylation (biological process) GO:0110165 - cellular anatomical structure (cellular component) GO:0008276 - protein methyltransferase activity (molecular function)
InterPro domains	IPR019410 - Lysine methyltransferase IPR038899 - Methyltransferase-like protein 22

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6570431.1 Protein N-lysine methyltransferase METTL21A, partial [Cucurbita argyrosperma subsp. sororia]

1.8e-61

72.43

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Query:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGV----------------
        MEREEEEEDIVCLDASFFMNNDYQLTTF FGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLS HAHLLQGCSIIELGSGV                
Subjt:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGV----------------

Query:  ----------------------------GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADIYILILSCSFFSRNVKMTKSVLVL
                                    GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADIYIL LS SF SRNV+MTKSVL+L
Subjt:  ----------------------------GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADIYILILSCSFFSRNVKMTKSVLVL

XP_022943521.1 protein N-lysine methyltransferase METTL21A [Cucurbita moschata]

1.6e-52

71.6

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Query:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGV----------------
        MEREEEEEDIVCLDASFFMNNDYQLTTF FGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLS HAHLLQGCSIIELGSGV                
Subjt:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGV----------------

Query:  ----------------------------GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI
                                    GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI
Subjt:  ----------------------------GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI

XP_022985666.1 protein N-lysine methyltransferase METTL21A [Cucurbita maxima]

1.6e-52

71.6

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Query:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGV----------------
        MEREEEEEDIVCLDASFFMNNDYQLTTF FGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLS HAHLLQGCSIIELGSGV                
Subjt:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGV----------------

Query:  ----------------------------GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI
                                    GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI
Subjt:  ----------------------------GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI

XP_023513367.1 protein N-lysine methyltransferase METTL21A [Cucurbita pepo subsp. pepo]

1.6e-52

71.6

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Query:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGV----------------
        MEREEEEEDIVCLDASFFMNNDYQLTTF FGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLS HAHLLQGCSIIELGSGV                
Subjt:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGV----------------

Query:  ----------------------------GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI
                                    GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI
Subjt:  ----------------------------GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI

XP_038901029.1 protein N-lysine methyltransferase METTL21A [Benincasa hispida]

7.8e-52

69.75

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Query:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGV----------------
        MEREEEE+DIVCLD SFF+NNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGH+HLLQGCSIIELGSGV                
Subjt:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGV----------------

Query:  ----------------------------GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI
                                    GL AEKLEWGNSDQITQVIDKYSGGFDLILGADI
Subjt:  ----------------------------GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KI86 Uncharacterized protein

5.6e-56

70.52

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Query:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGVG---------------
        MEREEEEEDIVCLD SFFMNNDYQLTTFTFGSHEIEL CLQSASTDFDLTGQLVWPGALLMNNYLS HAHLLQGCSIIELGSGVG               
Subjt:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGVG---------------

Query:  -----------------------------LVAEKLEWGNSDQITQVIDKYSGGFDLILGADIYILILSCSFFS
                                     L AEKLEWGNSDQITQV+DK+SGGFDLILGADIYILILS SFFS
Subjt:  -----------------------------LVAEKLEWGNSDQITQVIDKYSGGFDLILGADIYILILSCSFFS

A0A1S3BNE5 protein N-lysine methyltransferase METTL21A isoform X1

5.4e-51

69.14

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Query:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGVG---------------
        MEREEEEEDIVCLD SFFMNNDYQLTTFTFGSHEIEL CLQSASTDFDLTGQLVWPGALLMNNYLS HAHLLQGCSIIELGSGVG               
Subjt:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGVG---------------

Query:  -----------------------------LVAEKLEWGNSDQITQVIDKYSGGFDLILGADI
                                     L AEKLEWGNSDQITQV+DK+SGGFDLILGADI
Subjt:  -----------------------------LVAEKLEWGNSDQITQVIDKYSGGFDLILGADI

A0A6J1DFS1 protein N-lysine methyltransferase METTL21A

1.9e-51

69.14

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Query:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGV----------------
        MEREEEEEDIVCLDASFFMNNDY+LTTFTFGSH IELLCLQSASTDFDLTGQLVWPGALL+NNYLS HAHLLQGCSIIELGSGV                
Subjt:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGV----------------

Query:  ----------------------------GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI
                                    GLVAEKLEWGNSDQITQ++DKYSGGFDLILGADI
Subjt:  ----------------------------GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI

A0A6J1FRY5 protein N-lysine methyltransferase METTL21A

7.6e-53

71.6

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Query:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGV----------------
        MEREEEEEDIVCLDASFFMNNDYQLTTF FGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLS HAHLLQGCSIIELGSGV                
Subjt:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGV----------------

Query:  ----------------------------GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI
                                    GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI
Subjt:  ----------------------------GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI

A0A6J1J8W1 protein N-lysine methyltransferase METTL21A

7.6e-53

71.6

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Query:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGV----------------
        MEREEEEEDIVCLDASFFMNNDYQLTTF FGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLS HAHLLQGCSIIELGSGV                
Subjt:  MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGV----------------

Query:  ----------------------------GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI
                                    GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI
Subjt:  ----------------------------GLVAEKLEWGNSDQITQVIDKYSGGFDLILGADI

SwissProt top hits

e value

%identity

Alignment

Q8R1C6 Methyltransferase-like protein 22

6.3e-04

42.22

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Query:  STDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGVGLVA
        +T  +  G+ VW GALL+ +Y+     L QGC+++ELG+G GL +
Subjt:  STDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGVGLVA

Arabidopsis top hits

e value

%identity

Alignment

AT2G26810.1 Putative methyltransferase family protein

1.5e-40

55.35

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Query:  EEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGVG------------------
        EEEEE+IVCL+ SFF+N+DYQLT FTFGSH +EL CLQSASTDFDLTGQLVWPGA+LMN YLS +A +LQGCS++ELGSGVG                  
Subjt:  EEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGVG------------------

Query:  --------------------------LVAEKLEWGNSDQITQVIDKYSGGFDLILGADI
                                  L A KLEWGNSDQ+ Q++ K++ GFDLILGADI
Subjt:  --------------------------LVAEKLEWGNSDQITQVIDKYSGGFDLILGADI

AT2G26810.2 Putative methyltransferase family protein

1.5e-40

55.35

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Query:  EEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGVG------------------
        EEEEE+IVCL+ SFF+N+DYQLT FTFGSH +EL CLQSASTDFDLTGQLVWPGA+LMN YLS +A +LQGCS++ELGSGVG                  
Subjt:  EEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGVG------------------

Query:  --------------------------LVAEKLEWGNSDQITQVIDKYSGGFDLILGADI
                                  L A KLEWGNSDQ+ Q++ K++ GFDLILGADI
Subjt:  --------------------------LVAEKLEWGNSDQITQVIDKYSGGFDLILGADI

AT2G26810.3 Putative methyltransferase family protein

9.2e-43

55.03

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Query:  EEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGVG------------------
        EEEEE+IVCL+ SFF+N+DYQLT FTFGSH +EL CLQSASTDFDLTGQLVWPGA+LMN YLS +A +LQGCS++ELGSGVG                  
Subjt:  EEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGVG------------------

Query:  --------------------------LVAEKLEWGNSDQITQVIDKYSGGFDLILGADIYILILSCSFF
                                  L A KLEWGNSDQ+ Q++ K++ GFDLILGADIYIL+    FF
Subjt:  --------------------------LVAEKLEWGNSDQITQVIDKYSGGFDLILGADIYILILSCSFF

Sequences

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CDS sequence

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ATGGAGAGAGAAGAGGAAGAAGAAGACATAGTTTGTTTAGATGCCTCATTCTTTATGAACAACGACTATCAGCTCACCACGTTTACATTCGGCTCCCATGAGATTGAACT
CCTCTGTCTTCAGTCTGCTTCCACTGATTTTGATTTAACGGGGCAATTAGTGTGGCCCGGTGCCTTGCTGATGAACAATTATCTTTCCGGACACGCTCACCTGCTTCAAG
GATGTTCTATCATTGAATTAGGATCTGGTGTCGGACTAGTAGCTGAGAAGCTTGAATGGGGAAATTCTGATCAGATAACCCAAGTTATAGACAAGTATTCTGGTGGATTT
GATCTAATTCTTGGTGCTGATATCTATATCCTGATTCTTTCTTGTTCATTTTTCTCAAGAAATGTTAAAATGACAAAATCAGTTTTGGTGTTAGACAGTAGAGATATAGA
ATGA

mRNA sequence

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Protein sequence

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MEREEEEEDIVCLDASFFMNNDYQLTTFTFGSHEIELLCLQSASTDFDLTGQLVWPGALLMNNYLSGHAHLLQGCSIIELGSGVGLVAEKLEWGNSDQITQVIDKYSGGF
DLILGADIYILILSCSFFSRNVKMTKSVLVLDSRDIE

HG10001210 (gene) of Bottle gourd (Hangzhou Gourd) v1 genome