CuGenDBv2

Gene ID	HG10002934
Organism	Lagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
Description	Methionine gamma-lyase
Genome location	Chr11:15557083..15557382
RNA-Seq Expression	HG10002934
Synteny	HG10002934
Gene Ontology terms	GO:0019343 - cysteine biosynthetic process via cystathionine (biological process) GO:0019346 - transsulfuration (biological process) GO:0005737 - cytoplasm (cellular component) GO:0004123 - cystathionine gamma-lyase activity (molecular function) GO:0030170 - pyridoxal phosphate binding (molecular function)
InterPro domains	IPR000277 - Cys/Met metabolism, pyridoxal phosphate-dependent enzyme IPR015422 - Pyridoxal phosphate-dependent transferase, small domain IPR015424 - Pyridoxal phosphate-dependent transferase

Homology

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GenBank top hits

e value

%identity

Alignment

ADN33936.1 cystathionine gamma-synthase [Cucumis melo subsp. melo]

1.9e-46

95.96

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Query:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN
        MLCVDMGTEERANKLM+ILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEE+ELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQD+G+PFCNN
Subjt:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN

KAA0052969.1 methionine gamma-lyase-like [Cucumis melo var. makuwa]

1.9e-46

95.96

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Query:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN
        MLCVDMGTEERANKLM+ILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEE+ELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQD+G+PFCNN
Subjt:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN

NP_001315378.1 methionine gamma-lyase-like [Cucumis melo]

1.9e-46

95.96

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Query:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN
        MLCVDMGTEERANKLM+ILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEE+ELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQD+G+PFCNN
Subjt:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN

XP_004146134.1 methionine gamma-lyase [Cucumis sativus]

9.6e-46

94.95

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Query:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN
        MLCVDMGTEE+ANKLM+ILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEE+ELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQD G+PFCNN
Subjt:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN

XP_038876588.1 methionine gamma-lyase-like [Benincasa hispida]

2.1e-45

93.94

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Query:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN
        MLC+DMGTEERANKLMN+LQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTL+QKWSQFEKALAK+QDMGLP  NN
Subjt:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN

TrEMBL top hits

e value

%identity

Alignment

A0A0A0L129 Uncharacterized protein

4.6e-46

94.95

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Query:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN
        MLCVDMGTEE+ANKLM+ILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEE+ELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQD G+PFCNN
Subjt:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN

A0A1S3BKU9 methionine gamma-lyase-like

9.3e-47

95.96

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Query:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN
        MLCVDMGTEERANKLM+ILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEE+ELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQD+G+PFCNN
Subjt:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN

A0A5A7UHF4 Methionine gamma-lyase-like

9.3e-47

95.96

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Query:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN
        MLCVDMGTEERANKLM+ILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEE+ELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQD+G+PFCNN
Subjt:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN

E5RDC8 Cystathionine gamma-synthase

9.3e-47

95.96

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Query:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN
        MLCVDMGTEERANKLM+ILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEE+ELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQD+G+PFCNN
Subjt:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN

M1NFB7 Methionine gamma-lyase

9.3e-47

95.96

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Query:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN
        MLCVDMGTEERANKLM+ILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEE+ELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQD+G+PFCNN
Subjt:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN

SwissProt top hits

e value

%identity

Alignment

Q8L0X4 L-methionine gamma-lyase

2.5e-04

40.85

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Query:  LQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKV
        L N  +   +AVSLG  ETL+    S T S  + EE+E AGI+ GLVR+S+G +  +E   +  E+ L K+
Subjt:  LQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKV

Q8RDT4 L-methionine gamma-lyase

1.5e-04

40.85

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Query:  LQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKV
        L N  +   +AVSLG  ETL+    S T S  + EE+E+AGI+ GLVR+S+G +  +E   +  E+ L K+
Subjt:  LQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKV

Q9SGU9 Methionine gamma-lyase

7.4e-33

76.4

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Query:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKV
        +L +DM TEE+ANKLM  LQN TQFGFMAVSLGYYETLMSCSGSSTSSE+   +KE AGISPGLVRMS+GY+GTLEQKW+QFEKA  ++
Subjt:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKV

Arabidopsis top hits

e value

%identity

Alignment

AT1G64660.1 methionine gamma-lyase

5.3e-34

76.4

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Query:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKV
        +L +DM TEE+ANKLM  LQN TQFGFMAVSLGYYETLMSCSGSSTSSE+   +KE AGISPGLVRMS+GY+GTLEQKW+QFEKA  ++
Subjt:  MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKV

Sequences

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CDS sequence

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ATGTTGTGCGTGGACATGGGGACCGAGGAAAGGGCAAACAAGCTCATGAACATACTCCAAAACACTACCCAATTTGGGTTCATGGCAGTGAGTTTAGGGTACTATGAAAC
CCTAATGTCATGCTCAGGCAGCAGCACAAGCAGTGAAATGAGTGGAGAGGAAAAGGAATTGGCTGGAATCTCACCAGGGCTTGTAAGAATGTCTATTGGATATATGGGCA
CATTGGAGCAAAAGTGGAGCCAATTTGAGAAGGCTCTTGCCAAAGTGCAAGACATGGGGCTTCCATTTTGCAACAATTAA

mRNA sequence

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Protein sequence

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MLCVDMGTEERANKLMNILQNTTQFGFMAVSLGYYETLMSCSGSSTSSEMSGEEKELAGISPGLVRMSIGYMGTLEQKWSQFEKALAKVQDMGLPFCNN

HG10002934 (gene) of Bottle gourd (Hangzhou Gourd) v1 genome