CuGenDBv2

Gene ID	HG10003420
Organism	Lagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
Description	E3 ubiquitin-protein ligase
Genome location	Chr08:1065077..1065364
RNA-Seq Expression	HG10003420
Synteny	HG10003420
Gene Ontology terms	GO:0000209 - protein polyubiquitination (biological process) GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process (biological process) GO:0000151 - ubiquitin ligase complex (cellular component) GO:0005737 - cytoplasm (cellular component) GO:0031624 - ubiquitin conjugating enzyme binding (molecular function) GO:0046872 - metal ion binding (molecular function) GO:0061630 - ubiquitin protein ligase activity (molecular function)
InterPro domains	IPR013083 - Zinc finger, RING/FYVE/PHD-type IPR017907 - Zinc finger, RING-type, conserved site IPR031127 - E3 ubiquitin ligase RBR family

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0039247.1 putative E3 ubiquitin-protein ligase RNF217 isoform X2 [Cucumis melo var. makuwa]

8.1e-34

73.33

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Query:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL-YCPFVDCSVMLINDG
        MFT++ECSH FCKDCIS+HIAAK+EDNIAN+KCP+  C+ +L P+ICHSF+PKNL DRWGDVLCE  ILG  RL YCPF+DCSV LI+DG
Subjt:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL-YCPFVDCSVMLINDG

KAE8649011.1 hypothetical protein Csa_009107 [Cucumis sativus]

5.1e-36

72.63

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Query:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL-YCPFVDCSVMLINDGGRVSE
        MFT++ECSH FCKDCISNHIAAK+EDNIAN+KCP+PGCE VL P++CHSF+PKN+LDRWG VLCE  ILG  RL YCPF+DCSV LI+DG   ++
Subjt:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL-YCPFVDCSVMLINDGGRVSE

XP_004141646.1 probable E3 ubiquitin-protein ligase ARI3 [Cucumis sativus]

5.1e-36

72.63

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Query:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL-YCPFVDCSVMLINDGGRVSE
        MFT++ECSH FCKDCISNHIAAK+EDNIAN+KCP+PGCE VL P++CHSF+PKN+LDRWG VLCE  ILG  RL YCPF+DCSV LI+DG   ++
Subjt:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL-YCPFVDCSVMLINDGGRVSE

XP_022152679.1 E3 ubiquitin-protein ligase RNF144A-like [Momordica charantia]

4.9e-31

65.59

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Query:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRLYCPFVDCSVMLINDGGRVS
        MFTS+ CSH FC DCIS HIAAK+EDNIA +KCPEP CE+ L+P +C SF+P+ +L+RWGD LCE  ILGI R+YCPFVDCS  +I+DGG  +
Subjt:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRLYCPFVDCSVMLINDGGRVS

XP_030968567.1 E3 ubiquitin-protein ligase RNF144A-like [Quercus lobata]

5.6e-27

53.26

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Query:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRLYCPFVDCSVMLINDGGRV
        MFT+N C+H FC  CIS ++A K++DNI+++KCP+P C  +L+P  C   +P+ + DRWGD LCE  ILG Q+ YCP+ DCS ML++DGG V
Subjt:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRLYCPFVDCSVMLINDGGRV

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KSV5 Uncharacterized protein

2.4e-36

72.63

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Query:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL-YCPFVDCSVMLINDGGRVSE
        MFT++ECSH FCKDCISNHIAAK+EDNIAN+KCP+PGCE VL P++CHSF+PKN+LDRWG VLCE  ILG  RL YCPF+DCSV LI+DG   ++
Subjt:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL-YCPFVDCSVMLINDGGRVSE

A0A5A7TCD1 Putative E3 ubiquitin-protein ligase RNF217 isoform X2

3.9e-34

73.33

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Query:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL-YCPFVDCSVMLINDG
        MFT++ECSH FCKDCIS+HIAAK+EDNIAN+KCP+  C+ +L P+ICHSF+PKNL DRWGDVLCE  ILG  RL YCPF+DCSV LI+DG
Subjt:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL-YCPFVDCSVMLINDG

A0A6J1DGR7 E3 ubiquitin-protein ligase RNF144A-like

2.4e-31

65.59

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Query:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRLYCPFVDCSVMLINDGGRVS
        MFTS+ CSH FC DCIS HIAAK+EDNIA +KCPEP CE+ L+P +C SF+P+ +L+RWGD LCE  ILGI R+YCPFVDCS  +I+DGG  +
Subjt:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRLYCPFVDCSVMLINDGGRVS

A0A7N2LM99 Uncharacterized protein

2.7e-27

53.26

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Query:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRLYCPFVDCSVMLINDGGRV
        MFT+N C+H FC  CIS ++A K++DNI+++KCP+P C  +L+P  C   +P+ + DRWGD LCE  ILG Q+ YCP+ DCS ML++DGG V
Subjt:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRLYCPFVDCSVMLINDGGRV

A0A7N2R445 Uncharacterized protein

2.7e-27

53.26

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Query:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRLYCPFVDCSVMLINDGGRV
        MFT+N C+H FC  CIS ++A K++DNI+++KCP+P C  +L+P  C   +P+ + DRWGD LCE  ILG Q+ YCP+ DCS ML++DGG V
Subjt:  MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRLYCPFVDCSVMLINDGGRV

SwissProt top hits

e value

%identity

Alignment

A2VEA3 E3 ubiquitin-protein ligase ARIH1

6.9e-04

29.76

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Query:  FTSNECSHFFCKDCISNHIAAKV--EDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL--YCPFVDC
        FT  EC H FC  C S ++  K+  E     I CP  GC+ ++D N     +  + +      L   + +   RL  +CP  DC
Subjt:  FTSNECSHFFCKDCISNHIAAKV--EDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL--YCPFVDC

B1H1E4 E3 ubiquitin-protein ligase arih1

6.9e-04

29.76

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Query:  FTSNECSHFFCKDCISNHIAAKV--EDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL--YCPFVDC
        FT  EC H FC  C S ++  K+  E     I CP  GC+ ++D N     +  + +      L   + +   RL  +CP  DC
Subjt:  FTSNECSHFFCKDCISNHIAAKV--EDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL--YCPFVDC

Q9Y4X5 E3 ubiquitin-protein ligase ARIH1

6.9e-04

29.76

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Query:  FTSNECSHFFCKDCISNHIAAKV--EDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL--YCPFVDC
        FT  EC H FC  C S ++  K+  E     I CP  GC+ ++D N     +  + +      L   + +   RL  +CP  DC
Subjt:  FTSNECSHFFCKDCISNHIAAKV--EDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL--YCPFVDC

Q9Z1K5 E3 ubiquitin-protein ligase ARIH1

6.9e-04

29.76

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Query:  FTSNECSHFFCKDCISNHIAAKV--EDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL--YCPFVDC
        FT  EC H FC  C S ++  K+  E     I CP  GC+ ++D N     +  + +      L   + +   RL  +CP  DC
Subjt:  FTSNECSHFFCKDCISNHIAAKV--EDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRL--YCPFVDC

Arabidopsis top hits

e value

%identity

Alignment

AT3G14250.1 RING/U-box superfamily protein

1.9e-20

38.82

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Query:  SNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRLYCPFVDCSVMLIND
        +  C+H +C DC   ++A K+++N + IKCP+  C  +++P  C   +PK++ DRW  +LCE  I    + YCPF DCS M++N+
Subjt:  SNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRLYCPFVDCSVMLIND

AT3G53690.1 RING/U-box superfamily protein

7.3e-25

46.15

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Query:  FTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRLYCPFVDCSVMLINDGGRV
        F    CSHF+C DC+S +IAAK++DNI +I+CP  GC   L+P+ C   LPK + DRWGD LCE  ++  ++ YCP+ DCS ++  +   V
Subjt:  FTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRLYCPFVDCSVMLINDGGRV

Sequences

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CDS sequence

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ATGTTCACAAGCAACGAGTGCTCCCATTTCTTCTGCAAAGATTGCATCTCTAATCACATAGCGGCCAAAGTGGAAGACAATATAGCCAACATCAAGTGTCCAGAGCCAGG
TTGTGAGACAGTGCTAGACCCCAACATCTGCCATTCATTCCTCCCCAAAAACCTGTTGGATCGCTGGGGAGATGTGTTATGTGAGGTCGCCATTCTCGGCATCCAGAGAC
TCTACTGCCCCTTCGTGGACTGCTCGGTGATGCTTATCAATGATGGAGGCCGAGTGTCTGAGCTGTAA

mRNA sequence

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Protein sequence

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MFTSNECSHFFCKDCISNHIAAKVEDNIANIKCPEPGCETVLDPNICHSFLPKNLLDRWGDVLCEVAILGIQRLYCPFVDCSVMLINDGGRVSEL

HG10003420 (gene) of Bottle gourd (Hangzhou Gourd) v1 genome