CuGenDBv2

Gene ID	HG10004893
Organism	Lagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
Description	mediator of RNA polymerase II transcription subunit 18
Genome location	Chr08:21236516..21237839
RNA-Seq Expression	HG10004893
Synteny	HG10004893
Gene Ontology terms	GO:0006357 - regulation of transcription by RNA polymerase II (biological process) GO:0006369 - termination of RNA polymerase II transcription (biological process) GO:0016592 - mediator complex (cellular component) GO:0070847 - core mediator complex (cellular component) GO:0003712 - transcription coregulator activity (molecular function)
InterPro domains	IPR019095 - Mediator complex, subunit Med18

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0065265.1 mediator of RNA polymerase II transcription subunit 18 [Cucumis melo var. makuwa]

2.0e-86

99.42

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Query:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST
        LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRF+RGAHITVTVSSVNKMLKLHST
Subjt:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST

Query:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
        DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
Subjt:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM

XP_008444669.1 PREDICTED: mediator of RNA polymerase II transcription subunit 18 [Cucumis melo]

2.0e-86

99.42

Show/hide

Query:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST
        LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRF+RGAHITVTVSSVNKMLKLHST
Subjt:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST

Query:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
        DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
Subjt:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM

XP_011649597.2 mediator of RNA polymerase II transcription subunit 18 isoform X1 [Cucumis sativus]

4.0e-87

100

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Query:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST
        LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST
Subjt:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST

Query:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
        DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
Subjt:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM

XP_011649598.2 mediator of RNA polymerase II transcription subunit 18 isoform X2 [Cucumis sativus]

3.0e-87

99.43

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Query:  MLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHS
        +LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHS
Subjt:  MLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHS

Query:  TDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
        TDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
Subjt:  TDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM

XP_038885244.1 mediator of RNA polymerase II transcription subunit 18 [Benincasa hispida]

5.2e-87

99.42

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Query:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST
        LGAVASE+RILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST
Subjt:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST

Query:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
        DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
Subjt:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LNJ4 Uncharacterized protein

4.7e-86

99.43

Show/hide

Query:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST
        LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST
Subjt:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST

Query:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS-DGAGTTM
        DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS DGAGTTM
Subjt:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLS-DGAGTTM

A0A1S3BBM1 mediator of RNA polymerase II transcription subunit 18

9.5e-87

99.42

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Query:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST
        LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRF+RGAHITVTVSSVNKMLKLHST
Subjt:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST

Query:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
        DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
Subjt:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM

A0A5A7VHE6 Mediator of RNA polymerase II transcription subunit 18

9.5e-87

99.42

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Query:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST
        LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRF+RGAHITVTVSSVNKMLKLHST
Subjt:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST

Query:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
        DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
Subjt:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM

A0A6J1CS50 mediator of RNA polymerase II transcription subunit 18

4.7e-86

98.27

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Query:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST
        LGAVASEVRILCDLEQAEP WTVKHIGGA+RGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST
Subjt:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST

Query:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
        DEAVPVTPGIQLVEVTAPATS+NYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
Subjt:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM

A0A6J1GHW3 mediator of RNA polymerase II transcription subunit 18

2.6e-84

95.38

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Query:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST
        LGAVASEVRI+CDLEQ EP+WTVKHIGGA+RG+GAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGF+FRFHRG HITVTVSSVNKMLKLHST
Subjt:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST

Query:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
        DEAVPVTPGIQLVEVTAPATS+NYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
Subjt:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM

SwissProt top hits

e value

%identity

Alignment

Q9SJZ6 Mediator of RNA polymerase II transcription subunit 18

1.4e-74

79.77

Show/hide

Query:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST
        LG V+SEVR+LCDL+Q EPTWTVKH+GGA+RGAGA+Q+SVLVR M+ESKVSKN LR+FYALGYKLDHELL+VGFAF F R AHI+V+VSSVNKM K+H+ 
Subjt:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST

Query:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
        DEAVPVTPG+Q+V+VTAPATS+NYSEVA AVS+FCE+LAPL+HLSKP ISTGVVPTAAAAAASL+SDG GTT+
Subjt:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM

Arabidopsis top hits

e value

%identity

Alignment

AT2G22370.1 unknown protein

9.8e-76

79.77

Show/hide

Query:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST
        LG V+SEVR+LCDL+Q EPTWTVKH+GGA+RGAGA+Q+SVLVR M+ESKVSKN LR+FYALGYKLDHELL+VGFAF F R AHI+V+VSSVNKM K+H+ 
Subjt:  LGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHST

Query:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM
        DEAVPVTPG+Q+V+VTAPATS+NYSEVA AVS+FCE+LAPL+HLSKP ISTGVVPTAAAAAASL+SDG GTT+
Subjt:  DEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM

Sequences

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CDS sequence

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ATGTTAGGTGCTGTGGCATCGGAGGTTCGGATCTTGTGCGACCTTGAGCAGGCTGAACCAACATGGACGGTTAAACATATTGGAGGGGCAATAAGAGGTGCAGGTGCTGA
ACAACTTTCTGTTCTGGTTAGGACAATGGTAGAAAGCAAAGTTAGCAAGAATGTGCTTCGTCTATTCTATGCACTTGGCTATAAGTTAGATCATGAGCTGTTGAGAGTTG
GTTTTGCTTTCCGCTTCCACCGGGGTGCCCACATAACAGTGACAGTTTCATCAGTTAATAAGATGTTAAAGCTACATTCAACTGATGAGGCTGTCCCTGTAACACCTGGT
ATACAGCTGGTCGAAGTGACAGCCCCAGCAACTTCTGATAACTATTCTGAAGTAGCTGGTGCAGTGTCGACTTTCTGTGAATATCTTGCACCGCTGCTGCATTTGTCAAA
ACCGGGAATATCGACAGGTGTTGTTCCTACTGCTGCTGCAGCTGCAGCATCTCTTCTATCTGATGGTGCAGGAACAACAATGTAG

mRNA sequence

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Protein sequence

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MLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRVGFAFRFHRGAHITVTVSSVNKMLKLHSTDEAVPVTPG
IQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM

HG10004893 (gene) of Bottle gourd (Hangzhou Gourd) v1 genome