CuGenDBv2

Gene ID	HG10007871
Organism	Lagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
Description	pseudouridylate synthase 7 homolog isoform X1
Genome location	Chr10:16285283..16286931
RNA-Seq Expression	HG10007871
Synteny	HG10007871
Gene Ontology terms	GO:0001522 - pseudouridine synthesis (biological process) GO:0008033 - tRNA processing (biological process) GO:0003723 - RNA binding (molecular function) GO:0009982 - pseudouridine synthase activity (molecular function)
InterPro domains	IPR001656 - Pseudouridine synthase, TruD IPR020103 - Pseudouridine synthase, catalytic domain superfamily IPR042214 - Pseudouridine synthase, TruD, catalytic domain

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAE8653626.1 hypothetical protein Csa_007629 [Cucumis sativus]

5.4e-50

89.43

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Query:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL
        MTGSYRRVFQ+PKDYEWELISYVDRNLPLAQSDL NLLKSQSVEISKE+KIADKSKNED LDST+QS CCKKN++LEAG    ENENGQGTQDPQMALKL
Subjt:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL

Query:  SFTLPTSSYATMAIRELLKTSTS
        SFTLP SSYATMAIRELLKTSTS
Subjt:  SFTLPTSSYATMAIRELLKTSTS

XP_031745921.1 multisubstrate pseudouridine synthase 7-like, partial [Cucumis sativus]

5.4e-50

89.43

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Query:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL
        MTGSYRRVFQ+PKDYEWELISYVDRNLPLAQSDL NLLKSQSVEISKE+KIADKSKNED LDST+QS CCKKN++LEAG    ENENGQGTQDPQMALKL
Subjt:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL

Query:  SFTLPTSSYATMAIRELLKTSTS
        SFTLP SSYATMAIRELLKTSTS
Subjt:  SFTLPTSSYATMAIRELLKTSTS

XP_038878530.1 pseudouridylate synthase 7 homolog isoform X1 [Benincasa hispida]

4.1e-50

87.6

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Query:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENE--NGQGTQDPQMAL
        MTGSYRRVFQ+PKDYEWELISYVDRNLPLAQSDL NLLKSQSVEISKE+KIADKS NEDLLDSTEQSGCCKKNV+LEAGENENENE  N QG+QD Q+AL
Subjt:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENE--NGQGTQDPQMAL

Query:  KLSFTLPTSSYATMAIRELLKTSTSNKEV
        KLSFTLP SSYATMAIRELLKTSTS + +
Subjt:  KLSFTLPTSSYATMAIRELLKTSTSNKEV

XP_038878531.1 pseudouridylate synthase 7 homolog isoform X2 [Benincasa hispida]

5.4e-50

90.4

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Query:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENE--NGQGTQDPQMAL
        MTGSYRRVFQ+PKDYEWELISYVDRNLPLAQSDL NLLKSQSVEISKE+KIADKS NEDLLDSTEQSGCCKKNV+LEAGENENENE  N QG+QD Q+AL
Subjt:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENE--NGQGTQDPQMAL

Query:  KLSFTLPTSSYATMAIRELLKTSTS
        KLSFTLP SSYATMAIRELLKTSTS
Subjt:  KLSFTLPTSSYATMAIRELLKTSTS

XP_038878533.1 pseudouridylate synthase 7 homolog isoform X3 [Benincasa hispida]

4.1e-50

87.6

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Query:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENE--NGQGTQDPQMAL
        MTGSYRRVFQ+PKDYEWELISYVDRNLPLAQSDL NLLKSQSVEISKE+KIADKS NEDLLDSTEQSGCCKKNV+LEAGENENENE  N QG+QD Q+AL
Subjt:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENE--NGQGTQDPQMAL

Query:  KLSFTLPTSSYATMAIRELLKTSTSNKEV
        KLSFTLP SSYATMAIRELLKTSTS + +
Subjt:  KLSFTLPTSSYATMAIRELLKTSTSNKEV

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LYD2 Uncharacterized protein

2.6e-50

89.43

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Query:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL
        MTGSYRRVFQ+PKDYEWELISYVDRNLPLAQSDL NLLKSQSVEISKE+KIADKSKNED LDST+QS CCKKN++LEAG    ENENGQGTQDPQMALKL
Subjt:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL

Query:  SFTLPTSSYATMAIRELLKTSTS
        SFTLP SSYATMAIRELLKTSTS
Subjt:  SFTLPTSSYATMAIRELLKTSTS

A0A1S3CHJ1 pseudouridylate synthase 7 homolog isoform X1

8.7e-46

84.55

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Query:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL
        MTGSYRRVFQ+PKDYEWELISYVDRNLPLAQSDL  LLKSQSVEISKE+KIA+KSK ED LDST+QS CCKK+++LEAG   NE E GQGT DPQMALKL
Subjt:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL

Query:  SFTLPTSSYATMAIRELLKTSTS
        SFTLP SSYATMAIRELLKTSTS
Subjt:  SFTLPTSSYATMAIRELLKTSTS

A0A1S3CI40 pseudouridylate synthase 7 homolog isoform X2

8.7e-46

84.55

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Query:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL
        MTGSYRRVFQ+PKDYEWELISYVDRNLPLAQSDL  LLKSQSVEISKE+KIA+KSK ED LDST+QS CCKK+++LEAG   NE E GQGT DPQMALKL
Subjt:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL

Query:  SFTLPTSSYATMAIRELLKTSTS
        SFTLP SSYATMAIRELLKTSTS
Subjt:  SFTLPTSSYATMAIRELLKTSTS

A0A5A7V3D9 Pseudouridylate synthase 7-like protein isoform X1

5.6e-45

83.74

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Query:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL
        MTGSYRRVFQ+PKDYEWELISYVDRNLPLAQSDL  LLKSQSV ISKE+KIA+KSK ED LDST+QS CCKK+++LEAG   NE E GQGT DPQMALKL
Subjt:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL

Query:  SFTLPTSSYATMAIRELLKTSTS
        SFTLP SSYATMAIRELLKTSTS
Subjt:  SFTLPTSSYATMAIRELLKTSTS

A0A5D3DZA9 Pseudouridylate synthase 7-like protein isoform X2

5.6e-45

83.74

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Query:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL
        MTGSYRRVFQ+PKDYEWELISYVDRNLPLAQSDL  LLKSQSV ISKE+KIA+KSK ED LDST+QS CCKK+++LEAG   NE E GQGT DPQMALKL
Subjt:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL

Query:  SFTLPTSSYATMAIRELLKTSTS
        SFTLP SSYATMAIRELLKTSTS
Subjt:  SFTLPTSSYATMAIRELLKTSTS

SwissProt top hits

e value

%identity

Alignment

Q08647 Multisubstrate pseudouridine synthase 7

8.5e-06

31.82

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Query:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL
        + GSYR V QKPK  E+ +I Y D +  L  +DL                        D+L++T      +K +K +  +    ++ G+ T     A+ L
Subjt:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL

Query:  SFTLPTSSYATMAIRELLKTSTSNKEVFGDVR
         F L TS+YATMA+REL+K  TS +    DV+
Subjt:  SFTLPTSSYATMAIRELLKTSTSNKEVFGDVR

Q08DI8 Pseudouridylate synthase 7 homolog

1.1e-05

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Query:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL
        ++G+YR++  +P++  WE+++Y D  +PL  +D+ NL        + E K                                              ALK+
Subjt:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL

Query:  SFTLPTSSYATMAIRELLKTSTSNK
         F+LP S+YATMAIRE+LK  TS K
Subjt:  SFTLPTSSYATMAIRELLKTSTSNK

Q91VU7 Pseudouridylate synthase 7 homolog

5.0e-06

28.8

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Query:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL
        ++G+YRR+  +P+   WE+++Y D  +PL  +D+ NL        + E K                                              ALK+
Subjt:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL

Query:  SFTLPTSSYATMAIRELLKTSTSNK
         F+LP S+YATMAIRE+LK  TS K
Subjt:  SFTLPTSSYATMAIRELLKTSTSNK

Q96PZ0 Pseudouridylate synthase 7 homolog

8.5e-06

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Query:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL
        ++G+YR++  +P++  WE+++Y D  +PL  +D+ NL        + E K                                              ALK+
Subjt:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKL

Query:  SFTLPTSSYATMAIRELLKTSTSNK
         F+LP S+YATMAIRE+LK  TS K
Subjt:  SFTLPTSSYATMAIRELLKTSTSNK

Arabidopsis top hits

e value

%identity

Alignment

AT3G04820.1 Pseudouridine synthase family protein

3.0e-22

48.8

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Query:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVE-ISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQ-GTQDPQMAL
        MTG YRRVFQKP D+EWEL++Y D N PLA++DL  +  ++ VE +   ++I D+S   D    T      + N+K +   NE E + G   ++  QMAL
Subjt:  MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVE-ISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQ-GTQDPQMAL

Query:  KLSFTLPTSSYATMAIRELLKTSTS
        K++ TLP+S YATMAIRELLKTSTS
Subjt:  KLSFTLPTSSYATMAIRELLKTSTS

Sequences

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CDS sequence

Show/hide CDS sequence

ATGACTGGAAGCTACCGGAGAGTTTTTCAAAAACCAAAGGACTATGAGTGGGAATTGATCTCATATGTTGATCGTAATTTACCCCTGGCACAGAGTGATTTACAGAACCT
TTTGAAGTCTCAAAGTGTTGAAATTAGCAAGGAAGACAAGATAGCCGATAAATCTAAAAATGAAGATTTATTGGATTCCACAGAACAATCAGGGTGCTGTAAAAAGAATG
TTAAACTTGAAGCAGGTGAAAATGAAAATGAAAATGAAAATGGGCAAGGCACTCAGGATCCTCAGATGGCTCTCAAGTTGAGCTTTACTCTGCCCACGTCTTCTTATGCT
ACGATGGCAATTAGAGAATTGTTGAAAACATCAACTTCTAATAAAGAGGTTTTTGGTGATGTTAGGCCGAAAAAACAAGAGATTTTGGCTAAGATTGAGGGGTTGGATGA
TTTGGAGGTGAAGCGTCTTCTTGATGACCAGTGCAAGGCCGAAAGGGATTCCCTTAGCCTCCACTTTGCTGAGGTGGTTAGGAAGGTGACCTTCAGTTGGTGGCAAAAAG
TCAAGGTGGCTTGGGCTAAGGAAGGAGACTGTAATACTTCTTTCTTCACAAAATGGCTAGTGGTCGGAAGAGTAGGAATAGGATTGGCCTTCTGGTCAAGGAGTCTGGGA
AGGTCCTCAAGGAAGATAAGGAGGTGGAGGAAGAGATTATTTCCTTCTTTTCGAATCTCTATGGGCTAG

mRNA sequence

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Protein sequence

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MTGSYRRVFQKPKDYEWELISYVDRNLPLAQSDLQNLLKSQSVEISKEDKIADKSKNEDLLDSTEQSGCCKKNVKLEAGENENENENGQGTQDPQMALKLSFTLPTSSYA
TMAIRELLKTSTSNKEVFGDVRPKKQEILAKIEGLDDLEVKRLLDDQCKAERDSLSLHFAEVVRKVTFSWWQKVKVAWAKEGDCNTSFFTKWLVVGRVGIGLAFWSRSLG
RSSRKIRRWRKRLFPSFRISMG

HG10007871 (gene) of Bottle gourd (Hangzhou Gourd) v1 genome