CuGenDBv2

Gene ID	HG10008166
Organism	Lagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
Description	Eukaryotic translation initiation factor 5A
Genome location	Chr10:20454244..20459035
RNA-Seq Expression	HG10008166
Synteny	HG10008166
Gene Ontology terms	GO:0006413 - translational initiation (biological process) GO:0045901 - positive regulation of translational elongation (biological process) GO:0045905 - positive regulation of translational termination (biological process) GO:0003743 - translation initiation factor activity (molecular function) GO:0003746 - translation elongation factor activity (molecular function) GO:0043022 - ribosome binding (molecular function)
InterPro domains	IPR001884 - Translation elongation factor IF5A-like IPR008991 - Translation protein SH3-like domain superfamily IPR012340 - Nucleic acid-binding, OB-fold IPR014722 - Ribosomal protein L2, domain 2 IPR019769 - Translation elongation factor, IF5A, hypusine site IPR020189 - Translation elongation factor, IF5A C-terminal

Homology

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GenBank top hits

e value

%identity

Alignment

PSS08119.1 Eukaryotic translation initiation factor 5A-2 [Actinidia chinensis var. chinensis]

5.5e-65

97.62

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSDEEHHF+SKADAGASKT+PQQAG IRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLLTQ
        FVSLLTENGNTKDDLRLPTDDNLLTQ
Subjt:  FVSLLTENGNTKDDLRLPTDDNLLTQ

XP_004146682.1 eukaryotic translation initiation factor 5A-2 [Cucumis sativus]

2.9e-66

100

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLLTQ
        FVSLLTENGNTKDDLRLPTDDNLLTQ
Subjt:  FVSLLTENGNTKDDLRLPTDDNLLTQ

XP_008443857.1 PREDICTED: eukaryotic translation initiation factor 5A-2 [Cucumis melo]

8.4e-66

99.21

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSDEEHHFDSKADAGASKTFPQQAG IRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLLTQ
        FVSLLTENGNTKDDLRLPTDDNLLTQ
Subjt:  FVSLLTENGNTKDDLRLPTDDNLLTQ

XP_022135162.1 eukaryotic translation initiation factor 5A-2-like [Momordica charantia]

1.9e-65

98.41

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSDEEHHFDSKADAGASKTFPQQAG IRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLLTQ
        FVSLLTENGNTKDDL+LPTDDNLLTQ
Subjt:  FVSLLTENGNTKDDLRLPTDDNLLTQ

XP_022930431.1 eukaryotic translation initiation factor 5A-2-like [Cucurbita moschata]

8.4e-66

99.21

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSDEEHHFDSKADAGASKTFPQQAG IRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLLTQ
        FVSLLTENGNTKDDLRLPTDDNLLTQ
Subjt:  FVSLLTENGNTKDDLRLPTDDNLLTQ

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LTB3 Eukaryotic translation initiation factor 5A

1.4e-66

100

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLLTQ
        FVSLLTENGNTKDDLRLPTDDNLLTQ
Subjt:  FVSLLTENGNTKDDLRLPTDDNLLTQ

A0A1S3B9T8 Eukaryotic translation initiation factor 5A

4.1e-66

99.21

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSDEEHHFDSKADAGASKTFPQQAG IRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLLTQ
        FVSLLTENGNTKDDLRLPTDDNLLTQ
Subjt:  FVSLLTENGNTKDDLRLPTDDNLLTQ

A0A5A7T0H1 Eukaryotic translation initiation factor 5A

4.1e-66

99.21

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSDEEHHFDSKADAGASKTFPQQAG IRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLLTQ
        FVSLLTENGNTKDDLRLPTDDNLLTQ
Subjt:  FVSLLTENGNTKDDLRLPTDDNLLTQ

A0A6J1EQX3 Eukaryotic translation initiation factor 5A

4.1e-66

99.21

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSDEEHHFDSKADAGASKTFPQQAG IRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLLTQ
        FVSLLTENGNTKDDLRLPTDDNLLTQ
Subjt:  FVSLLTENGNTKDDLRLPTDDNLLTQ

A0A6J1I076 Eukaryotic translation initiation factor 5A

4.1e-66

99.21

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSDEEHHFDSKADAGASKTFPQQAG IRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLLTQ
        FVSLLTENGNTKDDLRLPTDDNLLTQ
Subjt:  FVSLLTENGNTKDDLRLPTDDNLLTQ

SwissProt top hits

e value

%identity

Alignment

P69039 Eukaryotic translation initiation factor 5A-1

2.0e-65

95.97

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSDEEHHF+SKADAGASKT+PQQAG IRKNG+IVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIF GKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLL
        FVSLLTENGNTKDDLRLPTDDNLL
Subjt:  FVSLLTENGNTKDDLRLPTDDNLL

P69040 Eukaryotic translation initiation factor 5A-1

2.0e-65

95.97

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSDEEHHF+SKADAGASKT+PQQAG IRKNG+IVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIF GKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLL
        FVSLLTENGNTKDDLRLPTDDNLL
Subjt:  FVSLLTENGNTKDDLRLPTDDNLL

Q9AXJ4 Eukaryotic translation initiation factor 5A

8.8e-66

94.44

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSDEEHHF+SKADAGASKTFPQQAG IRKNGYIVIKNRPCKV+EVSTSKTGKHGHAKCHFV IDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLLTQ
        FVSLLTE GNTKDDLRLPTD+NLL+Q
Subjt:  FVSLLTENGNTKDDLRLPTDDNLLTQ

Q9AXQ3 Eukaryotic translation initiation factor 5A-4

3.3e-65

94.44

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSDEEHHF+SKADAGASKT+PQQAG IRKNGYIVIK RPCKVVEVSTSKTGKHGHAKCHFVAIDIFN KKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLLTQ
        FVSLLTENGNTKDDLRLPTDD LL Q
Subjt:  FVSLLTENGNTKDDLRLPTDDNLLTQ

Q9AXQ5 Eukaryotic translation initiation factor 5A-2

6.7e-66

93.02

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSDEEHHF+SKADAGASKTFPQQAG IRKNGYIVIK RPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLLTQTME
        FVSLLTE+GNTKDDLRLPTD+NLL Q  +
Subjt:  FVSLLTENGNTKDDLRLPTDDNLLTQTME

Arabidopsis top hits

e value

%identity

Alignment

AT1G13950.1 eukaryotic elongation factor 5A-1

1.0e-61

88.89

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSDEEHHF+S +DAGASKT+PQQAG IRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIF  KKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLLTQ
        +VSLLT+NG+TKDDL+LP DD LL Q
Subjt:  FVSLLTENGNTKDDLRLPTDDNLLTQ

AT1G26630.1 Eukaryotic translation initiation factor 5A-1 (eIF-5A 1) protein

5.8e-57

81.75

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSD+EHHF++ +++GASKT+PQ AG IRK G+IVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIF  KKLEDIVPSSHNCDVPHVNR DYQLIDI+EDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLLTQ
        FVSLLT++G TKDDL+LPTDD L  Q
Subjt:  FVSLLTENGNTKDDLRLPTDDNLLTQ

AT1G26630.2 Eukaryotic translation initiation factor 5A-1 (eIF-5A 1) protein

2.0e-57

77.21

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSD+EHHF++ +++GASKT+PQ AG IRK G+IVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIF  KKLEDIVPSSHNCDVPHVNR DYQLIDI+EDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLLTQTMELVTVLES
        FVSLLT++G TKDDL+LPTDD L  Q +  V   E+
Subjt:  FVSLLTENGNTKDDLRLPTDDNLLTQTMELVTVLES

AT1G69410.1 eukaryotic elongation factor 5A-3

1.6e-59

86.51

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Query:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG
        MSD+EHHF+S +DAGASKT+PQQAG IRK G+IVIK RPCKVVEVSTSKTGKHGHAKCHFVAIDIF  KKLEDIVPSSHNCDVPHVNR DYQLIDISEDG
Subjt:  MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDG

Query:  FVSLLTENGNTKDDLRLPTDDNLLTQ
        FVSLLT+NG+TKDDL+LPTD+ LLTQ
Subjt:  FVSLLTENGNTKDDLRLPTDDNLLTQ

Sequences

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CDS sequence

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ATGTCGGACGAGGAGCACCACTTCGACTCCAAGGCCGACGCCGGAGCTTCCAAGACTTTCCCTCAGCAAGCTGGAGCCATTCGCAAAAATGGCTACATCGTAATCAAGAA
CAGACCCTGCAAGGTTGTTGAAGTTTCGACTTCAAAAACTGGAAAGCACGGACATGCAAAGTGCCACTTTGTGGCAATTGACATATTCAATGGGAAGAAACTTGAAGATA
TTGTTCCTTCTTCTCATAACTGTGATGTTCCCCATGTTAATCGCACTGACTATCAGCTGATTGATATATCCGAGGATGGTTTTGTCAGTCTCCTTACTGAAAATGGAAAC
ACCAAGGATGACCTGAGGCTTCCCACCGATGATAACCTGCTTACGCAGACAATGGAATTAGTCACTGTATTAGAGTCAAAAGAGAAGCCTCCATGTGGCTATAAACGTCG
TGAAAACAAAACCGTCAAACCAAAAGAATCCAATGGTGATGAAACCATTGAACAAGATCCGACGGCTGTAGAGTAA

mRNA sequence

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Protein sequence

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MSDEEHHFDSKADAGASKTFPQQAGAIRKNGYIVIKNRPCKVVEVSTSKTGKHGHAKCHFVAIDIFNGKKLEDIVPSSHNCDVPHVNRTDYQLIDISEDGFVSLLTENGN
TKDDLRLPTDDNLLTQTMELVTVLESKEKPPCGYKRRENKTVKPKESNGDETIEQDPTAVE

HG10008166 (gene) of Bottle gourd (Hangzhou Gourd) v1 genome