CuGenDBv2

Gene ID	HG10008563
Organism	Lagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
Description	dCTP pyrophosphatase 1
Genome location	Chr10:24204712..24205243
RNA-Seq Expression	HG10008563
Synteny	HG10008563
Gene Ontology terms	GO:0006253 - dCTP catabolic process (biological process) GO:0042262 - DNA protection (biological process) GO:0005829 - cytosol (cellular component) GO:0000287 - magnesium ion binding (molecular function) GO:0047840 - dCTP diphosphatase activity (molecular function)
InterPro domains	IPR025984 - dCTP pyrophosphatase 1

Homology

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GenBank top hits

e value

%identity

Alignment

XP_004138182.1 dCTP pyrophosphatase 1 [Cucumis sativus]

1.6e-61

96.8

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL
        ME+RSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNGNKYPVAAFSRALP
        GHAALSKLVKN NKYPVAAF+RALP
Subjt:  GHAALSKLVKNGNKYPVAAFSRALP

XP_008453231.1 PREDICTED: dCTP pyrophosphatase 1-like [Cucumis melo]

1.7e-60

95.2

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL
        ME+RSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNGNKYPVAAFSRALP
        GHAA+SKLVKN NKYPVAA +RALP
Subjt:  GHAALSKLVKNGNKYPVAAFSRALP

XP_022921755.1 dCTP pyrophosphatase 1-like [Cucurbita moschata]

7.8e-61

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL
        ME+RSYEPEKTAKDVSLQELRD LAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNGNKYPVAAFSRALP
        GHAALSKLVKN NKYPVAAF+RALP
Subjt:  GHAALSKLVKNGNKYPVAAFSRALP

XP_022933743.1 dCTP pyrophosphatase 1-like isoform X2 [Cucurbita moschata]

3.0e-60

94.4

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL
        MESRSYEPEKTAKDVSL ELRDRLAEFA+VRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEE+SDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNGNKYPVAAFSRALP
        GHAALSK+VKN NKYPVAAF+RALP
Subjt:  GHAALSKLVKNGNKYPVAAFSRALP

XP_038880679.1 dCTP pyrophosphatase 1-like [Benincasa hispida]

2.7e-61

96.8

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL
        MES SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNGNKYPVAAFSRALP
        GHAALSKLVKN NKYPVAAF+RALP
Subjt:  GHAALSKLVKNGNKYPVAAFSRALP

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LP76 dCTP pyrophosphatase 1

7.6e-62

96.8

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL
        ME+RSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNGNKYPVAAFSRALP
        GHAALSKLVKN NKYPVAAF+RALP
Subjt:  GHAALSKLVKNGNKYPVAAFSRALP

A0A1S3BWI5 dCTP pyrophosphatase 1

8.4e-61

95.2

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL
        ME+RSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNGNKYPVAAFSRALP
        GHAA+SKLVKN NKYPVAA +RALP
Subjt:  GHAALSKLVKNGNKYPVAAFSRALP

A0A5A7UWT3 dCTP pyrophosphatase 1

8.4e-61

95.2

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL
        ME+RSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNGNKYPVAAFSRALP
        GHAA+SKLVKN NKYPVAA +RALP
Subjt:  GHAALSKLVKNGNKYPVAAFSRALP

A0A6J1E6P9 dCTP pyrophosphatase 1

3.8e-61

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL
        ME+RSYEPEKTAKDVSLQELRD LAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNGNKYPVAAFSRALP
        GHAALSKLVKN NKYPVAAF+RALP
Subjt:  GHAALSKLVKNGNKYPVAAFSRALP

A0A6J1JJF8 dCTP pyrophosphatase 1

1.4e-60

95.2

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Query:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL
        ME+RSYEPEKTAKDVSLQELRD L EFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAE+EHLEEEVSDVLLYLVRLADVCGLDL
Subjt:  MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDL

Query:  GHAALSKLVKNGNKYPVAAFSRALP
        GHAALSKLVKN NKYPVAAF+RALP
Subjt:  GHAALSKLVKNGNKYPVAAFSRALP

SwissProt top hits

e value

%identity

Alignment

Q32KY6 dCTP pyrophosphatase 1

8.5e-26

52.73

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Query:  PEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGHAALSK
        P   + + +L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   WS  E+  L+EE+SD+L+YLV LA  C +DL  A L K
Subjt:  PEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGHAALSK

Query:  LVKNGNKYPV
        +  N  +YPV
Subjt:  LVKNGNKYPV

Q91VC0 dCTP pyrophosphatase 1

1.3e-26

53.98

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Query:  SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGHAA
        S+ PE T     L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   W   E+  L+EE+SDVL+YLV LA  C +DL  A 
Subjt:  SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGHAA

Query:  LSKLVKNGNKYPV
        +SK+  N  +YPV
Subjt:  LSKLVKNGNKYPV

Q9H773 dCTP pyrophosphatase 1

8.5e-26

55.36

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Query:  SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGHAA
        S+ PE T     L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   WS  E+  L+EE+SDVL+YLV LA  C +DL  A 
Subjt:  SYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGHAA

Query:  LSKLVKNGNKYP
        LSK+  N  +YP
Subjt:  LSKLVKNGNKYP

Q9QY93 dCTP pyrophosphatase 1

1.7e-26

50.86

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Query:  ESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLG
        +S +  P + + + +L+++R   AEFA  R WEQ+H PRNLLLALVGEVGEL+E+FQWK + E G   W   E+  L+EE+SDVL+YLV LA  C +DL 
Subjt:  ESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLG

Query:  HAALSKLVKNGNKYPV
         A +SK+  N  +YPV
Subjt:  HAALSKLVKNGNKYPV

Arabidopsis top hits

e value

%identity

Alignment

AT3G25400.1 CONTAINS InterPro DOMAIN/s: NTP Pyrophosphohydrolase MazG-related, RS21-C6 (InterPro:IPR011394), EAR (InterPro:IPR009039), NTP pyrophosphohydrolase MazG, putative catalytic core (InterPro:IPR004518); Has 1123 Blast hits to 1121 proteins in 452 species: Archae - 22; Bacteria - 753; Metazoa - 81; Fungi - 3; Plants - 83; Viruses - 0; Other Eukaryotes - 181 (source: NCBI BLink).

3.8e-37

69.9

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Query:  VSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGHAALSKLVKNGNK
        VSLQ L  ++ +FA+ R WE+YHSPRNLLLA+VGEVGELSEIFQWKGEV RG P+W   EK HL EE+SDVLLYLVRL+D CG+DLG AAL K+  N  K
Subjt:  VSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGHAALSKLVKNGNK

Query:  YPV
        YPV
Subjt:  YPV

Sequences

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CDS sequence

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ATGGAGAGTCGTTCTTACGAACCTGAGAAAACCGCCAAAGACGTCTCACTGCAGGAACTCAGAGACAGGCTCGCAGAGTTCGCTCGAGTTCGAGGATGGGAACAATACCA
CAGCCCTAGAAACCTGCTCCTAGCACTTGTTGGTGAAGTCGGAGAGCTATCGGAGATATTCCAGTGGAAGGGCGAGGTGGAGAGGGGGCTGCCGAACTGGAGCGCGGCGG
AGAAAGAGCATTTGGAAGAAGAGGTATCGGATGTGTTGCTCTATTTGGTGCGTCTCGCCGATGTGTGTGGCCTTGATCTCGGCCATGCCGCTCTCTCAAAGCTCGTCAAA
AATGGCAACAAGTACCCTGTCGCGGCTTTCTCTCGCGCGCTCCCATGA

mRNA sequence

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Protein sequence

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MESRSYEPEKTAKDVSLQELRDRLAEFARVRGWEQYHSPRNLLLALVGEVGELSEIFQWKGEVERGLPNWSAAEKEHLEEEVSDVLLYLVRLADVCGLDLGHAALSKLVK
NGNKYPVAAFSRALP

HG10008563 (gene) of Bottle gourd (Hangzhou Gourd) v1 genome