CuGenDBv2

Gene ID	HG10009196
Organism	Lagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
Description	ubiquitin carboxyl-terminal hydrolase MINDY-1-like
Genome location	Chr06:3403669..3413811
RNA-Seq Expression	HG10009196
Synteny	HG10009196
Gene Ontology terms	GO:0071108 - protein K48-linked deubiquitination (biological process) GO:0004843 - thiol-dependent ubiquitin-specific protease activity (molecular function) GO:0016807 - cysteine-type carboxypeptidase activity (molecular function) GO:1990380 - Lys48-specific deubiquitinase activity (molecular function)
InterPro domains	IPR007518 - MINDY deubiquitinase IPR033979 - MINDY deubiquitinase domain

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

XP_004143997.2 ubiquitin carboxyl-terminal hydrolase MINDY-1 [Cucumis sativus]

0.0e+00

82.07

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Query:  MASSSSSEEPQNQPPQEQQQHLV------KEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE----
        MASSSS EE  NQPPQE  QH +      KEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLG DATEVSQEKLLSLVAE    
Subjt:  MASSSSSEEPQNQPPQEQQQHLV------KEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE----

Query:  -----------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHME
                                                 RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETAS+IDSKSYNAIMEELVALETQHME
Subjt:  -----------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHME

Query:  DPC-NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKV
        + C NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESP SISDEQ +RKGDLEEEAELLKAL+LSE+ETPIL+ NHGV SAEG+T   KLDEEPSP KV
Subjt:  DPC-NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKV

Query:  SVIDAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSG
        SVI+ VEKTIVKDICAADNNLN+QSDS   D+GKTS+SKSD DVSPFPNATEQ  SSS LKTDAG+HLDQ  ESEG+ I P  +EKDNHETL++TVTSSG
Subjt:  SVIDAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSG

Query:  RDGALVNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYE
        RDGAL NES E+ S MND  PFPAA ETVDHRPVDKEDP E+SG SP++ CTDS  G IQCIEAPEGLTS+VGSEPIYEGEECILDPRSTVLEDREPVYE
Subjt:  RDGALVNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYE

Query:  GEVVLAEQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKL
        GEVVLAEQGCGSSINF N QSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKL
Subjt:  GEVVLAEQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKL

Query:  NEVNGDTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQMVKS
        NEVNGDTLFMTSNFKEFKVESPSNESWDE NAMTSTADYLASIDATKH GMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQ+ ++
Subjt:  NEVNGDTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQMVKS

XP_008437192.1 PREDICTED: protein FAM63A isoform X2 [Cucumis melo]

7.7e-309

81.7

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Query:  ASSSSSEEPQNQPPQEQQQ----HLVKEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE-------
        +SSSSSEE QNQPPQE  Q       KEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLG DATEVSQEKLLSLVAE       
Subjt:  ASSSSSEEPQNQPPQEQQQ----HLVKEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE-------

Query:  --------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPC
                                              RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDH+TASAIDSKSYNAIMEELVALETQHMED C
Subjt:  --------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPC

Query:  -NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKVSVI
         NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESP SISDEQ +RKGDLEEEAELLKAL+LSE+ETPILM NHGV  AEG+T   KLDE PSP  VSVI
Subjt:  -NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKVSVI

Query:  DAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSGRDG
        + VEKTI KDICAADNNLN+QSDS   D+GKTS+SKSD DVSPFPNATEQ  SSS LK DAGKHLDQT ESEG+ ICP  +EK+NHETL++TVTSS  DG
Subjt:  DAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSGRDG

Query:  ALVNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEV
        AL NES E +S MND   FPAACETVDHRPVDKEDP E+SG SP+V CTDS  GKIQCIEAPEGLTS+VGSEPIYEGEECILDPRSTVLEDREPVYEGEV
Subjt:  ALVNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEV

Query:  VLAEQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEV
        VLAEQGCGSSINF N QSKVEISP+QGELIRNFLKNNASQLTFYGLFCLQ+GLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEV
Subjt:  VLAEQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEV

Query:  NGDTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQMVKS
        NGDTLFMTSNFKEFKVESPSNESWDE NAMTSTADYLASIDATKH G+DLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQ+ ++
Subjt:  NGDTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQMVKS

XP_016898824.1 PREDICTED: protein FAM63A isoform X1 [Cucumis melo]

9.5e-307

80.88

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Query:  ASSSSSEEPQNQPPQEQQQ----HLVKEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE-------
        +SSSSSEE QNQPPQE  Q       KEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLG DATEVSQEKLLSLVAE       
Subjt:  ASSSSSEEPQNQPPQEQQQ----HLVKEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE-------

Query:  --------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPC
                                              RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDH+TASAIDSKSYNAIMEELVALETQHMED C
Subjt:  --------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPC

Query:  -NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKVSVI
         NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESP SISDEQ +RKGDLEEEAELLKAL+LSE+ETPILM NHGV  AEG+T   KLDE PSP  VSVI
Subjt:  -NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKVSVI

Query:  DAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSGRDG
        + VEKTI KDICAADNNLN+QSDS   D+GKTS+SKSD DVSPFPNATEQ  SSS LK DAGKHLDQT ESEG+ ICP  +EK+NHETL++TVTSS  DG
Subjt:  DAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSGRDG

Query:  ALVNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEV
        AL NES E +S MND   FPAACETVDHRPVDKEDP E+SG SP+V CTDS  GKIQCIEAPEGLTS+VGSEPIYEGEECILDPRSTVLEDREPVYEGEV
Subjt:  ALVNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEV

Query:  VLAEQGCGSSINFCNTQSKVEISPKQ-------GELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLV
        VLAEQGCGSSINF N QSKVEISP+Q       GELIRNFLKNNASQLTFYGLFCLQ+GLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLV
Subjt:  VLAEQGCGSSINFCNTQSKVEISPKQ-------GELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLV

Query:  WEKLNEVNGDTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQMVK
        WEKLNEVNGDTLFMTSNFKEFKVESPSNESWDE NAMTSTADYLASIDATKH G+DLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQ+ +
Subjt:  WEKLNEVNGDTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQMVK

Query:  S
        +
Subjt:  S

XP_023549714.1 ubiquitin carboxyl-terminal hydrolase MINDY-1-like [Cucurbita pepo subsp. pepo]

1.1e-299

80.52

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Query:  MASSSSSEEPQNQPPQEQQQHLVKEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE----------
        MAS SSS+EP NQ  QEQQQ  VKEKEKECVYKTK IQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLG DATEVSQEKLLSLVAE          
Subjt:  MASSSSSEEPQNQPPQEQQQHLVKEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE----------

Query:  -----------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPC-NN
                                           RIDDFEFTPECAIFDLLDIPLYHGWIVD QDH+TA+AI SKSYNAIMEELVALETQHME  C NN
Subjt:  -----------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPC-NN

Query:  PEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKVSVIDAV
        PEDDCIDFVAATTATLGVPSP+LSK RSFDESP S+ DEQQMRKGDLEEEAELL+ALKLSE+ETPILM+NHGV +AEGDTN  KLDEE SPEKVSVID+V
Subjt:  PEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKVSVIDAV

Query:  EKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSGRDGALV
         KT+ KD CAADNNL+QQSDSSI DS K SLSK+DEDVSP  NATE   SSS L TDAGK LD+T ESEG+KICP  +EKDNHETL ETVTSSGR+GALV
Subjt:  EKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSGRDGALV

Query:  NESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEVVLA
        N+S E  S MNDK  F AA ETVDHRPVDKE PIELSGLSP+VTCTDS GGK QCI+ PEGLTS VGSEPIYEGEECILDP S+VLE REPVYEGEVV+A
Subjt:  NESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEVVLA

Query:  EQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGD
        EQGCGSS+NFC+  SK EISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGD
Subjt:  EQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGD

Query:  TLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQM
        TLFMTSNFKEFKVES SNESWDE NA+TSTADYLASIDA KH G+D NSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSS LVVGPQ+
Subjt:  TLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQM

XP_038874614.1 uncharacterized protein LOC120067199 [Benincasa hispida]

0.0e+00

88.01

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Query:  MASSSSSEEPQNQPPQE-QQQHLV--KEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE-------
        MASSSSSEE QNQPPQE QQQH V  KEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLG DATEVSQEKLLSLVAE       
Subjt:  MASSSSSEEPQNQPPQE-QQQHLV--KEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE-------

Query:  --------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPC
                                              RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHME  C
Subjt:  --------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPC

Query:  -NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKVSVI
         NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESP SISDEQQMRKGDLEEEAELLKALKLSETETPI MANHG+VSAEGDTN IKLDEEPSPEKVSVI
Subjt:  -NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKVSVI

Query:  DAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICPVEKDNHETLIETVTSSGRDGAL
        DAVEKTIVKDICAADNNLNQQS SSI DSGKTSL+ SDEDVSP PN TEQA SSS LKTDAGKHLDQT ESEGYKIC VEKDN ETLIETVTSSGRDGAL
Subjt:  DAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICPVEKDNHETLIETVTSSGRDGAL

Query:  VNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEVVL
        VNESSE  SQMNDK PFPAACETVDHRPVDKEDPIELSGLSP+VTCTDSEGGKIQCIE PEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEVVL
Subjt:  VNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEVVL

Query:  AEQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNG
        AEQGCGSSINFCNT SKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNG
Subjt:  AEQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNG

Query:  DTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQMVKS
        DTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKH G DLNSDLQLAIALQQQEFEQQPQR NVQQPSSGGSSRL+VGPQ+ ++
Subjt:  DTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQMVKS

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KR01 MINDY_DUB domain-containing protein

0.0e+00

82.07

Show/hide

Query:  MASSSSSEEPQNQPPQEQQQHLV------KEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE----
        MASSSS EE  NQPPQE  QH +      KEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLG DATEVSQEKLLSLVAE    
Subjt:  MASSSSSEEPQNQPPQEQQQHLV------KEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE----

Query:  -----------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHME
                                                 RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETAS+IDSKSYNAIMEELVALETQHME
Subjt:  -----------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHME

Query:  DPC-NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKV
        + C NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESP SISDEQ +RKGDLEEEAELLKAL+LSE+ETPIL+ NHGV SAEG+T   KLDEEPSP KV
Subjt:  DPC-NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKV

Query:  SVIDAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSG
        SVI+ VEKTIVKDICAADNNLN+QSDS   D+GKTS+SKSD DVSPFPNATEQ  SSS LKTDAG+HLDQ  ESEG+ I P  +EKDNHETL++TVTSSG
Subjt:  SVIDAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSG

Query:  RDGALVNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYE
        RDGAL NES E+ S MND  PFPAA ETVDHRPVDKEDP E+SG SP++ CTDS  G IQCIEAPEGLTS+VGSEPIYEGEECILDPRSTVLEDREPVYE
Subjt:  RDGALVNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYE

Query:  GEVVLAEQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKL
        GEVVLAEQGCGSSINF N QSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKL
Subjt:  GEVVLAEQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKL

Query:  NEVNGDTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQMVKS
        NEVNGDTLFMTSNFKEFKVESPSNESWDE NAMTSTADYLASIDATKH GMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQ+ ++
Subjt:  NEVNGDTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQMVKS

A0A1S3ATJ6 protein FAM63A isoform X2

3.7e-309

81.7

Show/hide

Query:  ASSSSSEEPQNQPPQEQQQ----HLVKEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE-------
        +SSSSSEE QNQPPQE  Q       KEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLG DATEVSQEKLLSLVAE       
Subjt:  ASSSSSEEPQNQPPQEQQQ----HLVKEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE-------

Query:  --------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPC
                                              RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDH+TASAIDSKSYNAIMEELVALETQHMED C
Subjt:  --------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPC

Query:  -NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKVSVI
         NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESP SISDEQ +RKGDLEEEAELLKAL+LSE+ETPILM NHGV  AEG+T   KLDE PSP  VSVI
Subjt:  -NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKVSVI

Query:  DAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSGRDG
        + VEKTI KDICAADNNLN+QSDS   D+GKTS+SKSD DVSPFPNATEQ  SSS LK DAGKHLDQT ESEG+ ICP  +EK+NHETL++TVTSS  DG
Subjt:  DAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSGRDG

Query:  ALVNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEV
        AL NES E +S MND   FPAACETVDHRPVDKEDP E+SG SP+V CTDS  GKIQCIEAPEGLTS+VGSEPIYEGEECILDPRSTVLEDREPVYEGEV
Subjt:  ALVNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEV

Query:  VLAEQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEV
        VLAEQGCGSSINF N QSKVEISP+QGELIRNFLKNNASQLTFYGLFCLQ+GLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEV
Subjt:  VLAEQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEV

Query:  NGDTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQMVKS
        NGDTLFMTSNFKEFKVESPSNESWDE NAMTSTADYLASIDATKH G+DLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQ+ ++
Subjt:  NGDTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQMVKS

A0A1S4DS61 protein FAM63A isoform X1

4.6e-307

80.88

Show/hide

Query:  ASSSSSEEPQNQPPQEQQQ----HLVKEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE-------
        +SSSSSEE QNQPPQE  Q       KEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLG DATEVSQEKLLSLVAE       
Subjt:  ASSSSSEEPQNQPPQEQQQ----HLVKEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE-------

Query:  --------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPC
                                              RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDH+TASAIDSKSYNAIMEELVALETQHMED C
Subjt:  --------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPC

Query:  -NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKVSVI
         NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESP SISDEQ +RKGDLEEEAELLKAL+LSE+ETPILM NHGV  AEG+T   KLDE PSP  VSVI
Subjt:  -NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKVSVI

Query:  DAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSGRDG
        + VEKTI KDICAADNNLN+QSDS   D+GKTS+SKSD DVSPFPNATEQ  SSS LK DAGKHLDQT ESEG+ ICP  +EK+NHETL++TVTSS  DG
Subjt:  DAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSGRDG

Query:  ALVNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEV
        AL NES E +S MND   FPAACETVDHRPVDKEDP E+SG SP+V CTDS  GKIQCIEAPEGLTS+VGSEPIYEGEECILDPRSTVLEDREPVYEGEV
Subjt:  ALVNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEV

Query:  VLAEQGCGSSINFCNTQSKVEISPKQ-------GELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLV
        VLAEQGCGSSINF N QSKVEISP+Q       GELIRNFLKNNASQLTFYGLFCLQ+GLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLV
Subjt:  VLAEQGCGSSINFCNTQSKVEISPKQ-------GELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLV

Query:  WEKLNEVNGDTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQMVK
        WEKLNEVNGDTLFMTSNFKEFKVESPSNESWDE NAMTSTADYLASIDATKH G+DLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQ+ +
Subjt:  WEKLNEVNGDTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQMVK

Query:  S
        +
Subjt:  S

A0A5A7TJ49 Protein FAM63A isoform X2

3.7e-309

81.7

Show/hide

Query:  ASSSSSEEPQNQPPQEQQQ----HLVKEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE-------
        +SSSSSEE QNQPPQE  Q       KEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLG DATEVSQEKLLSLVAE       
Subjt:  ASSSSSEEPQNQPPQEQQQ----HLVKEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE-------

Query:  --------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPC
                                              RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDH+TASAIDSKSYNAIMEELVALETQHMED C
Subjt:  --------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPC

Query:  -NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKVSVI
         NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESP SISDEQ +RKGDLEEEAELLKAL+LSE+ETPILM NHGV  AEG+T   KLDE PSP  VSVI
Subjt:  -NNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKVSVI

Query:  DAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSGRDG
        + VEKTI KDICAADNNLN+QSDS   D+GKTS+SKSD DVSPFPNATEQ  SSS LK DAGKHLDQT ESEG+ ICP  +EK+NHETL++TVTSS  DG
Subjt:  DAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSGRDG

Query:  ALVNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEV
        AL NES E +S MND   FPAACETVDHRPVDKEDP E+SG SP+V CTDS  GKIQCIEAPEGLTS+VGSEPIYEGEECILDPRSTVLEDREPVYEGEV
Subjt:  ALVNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEV

Query:  VLAEQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEV
        VLAEQGCGSSINF N QSKVEISP+QGELIRNFLKNNASQLTFYGLFCLQ+GLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEV
Subjt:  VLAEQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEV

Query:  NGDTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQMVKS
        NGDTLFMTSNFKEFKVESPSNESWDE NAMTSTADYLASIDATKH G+DLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQ+ ++
Subjt:  NGDTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQMVKS

A0A6J1I1B4 ubiquitin carboxyl-terminal hydrolase MINDY-1-like

1.2e-299

80.38

Show/hide

Query:  MASSSSSEEPQNQPPQEQQQHLVKEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE----------
        MAS SSS+EP NQ  QEQQQ  VKEKEKECVYKTK +QFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLG DATEVSQEKLLSLVAE          
Subjt:  MASSSSSEEPQNQPPQEQQQHLVKEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE----------

Query:  -----------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPC-NN
                                           RIDDFEFTPECAIFDLLDIPLYHGWIVD QDH+TA+AI SKSYNAIMEELVALETQHME  C NN
Subjt:  -----------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPC-NN

Query:  PEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKVSVIDAV
        PEDDCIDFVAATTATLGVPSP+LSK RSFDESP S+ DEQQMRKGDLEEEAELL+ALKLSE+ETPILM+NHGV +AEGDT   KLDEE SPEKVSVID+V
Subjt:  PEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKVSVIDAV

Query:  EKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSGRDGALV
         KT+ KD CAADNNL+QQSDSSI DS K SLSK+DEDV P  NATE   SSS L TDAGKHLDQT ESEG+KICP  +EKDNHETL E+VTSSGR+GALV
Subjt:  EKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICP--VEKDNHETLIETVTSSGRDGALV

Query:  NESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEVVLA
        N+S E  S MNDK  F AA ETVDHRPVDKE PIELSGLSP+VTCTDS GGKIQCI+ PEGLTS VGSEPIYEGEECILDP S+VLE REPVYEGEVV+A
Subjt:  NESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEVVLA

Query:  EQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGD
        EQGCGSS+NFC+  SK EISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGD
Subjt:  EQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGD

Query:  TLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQM
        TLFMTSNFKEFKVES SNESWDE NA+TSTADYLASIDA KH G+D NSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSS LVVGPQ+
Subjt:  TLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQM

SwissProt top hits

e value

%identity

Alignment

A3KQS4 Ubiquitin carboxyl-terminal hydrolase MINDY-1

7.7e-25

35.44

Show/hide

Query:  PEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEVVLAEQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVF
        PE +   +   P+Y G   ++DP+S      E V     +   Q     I F ++    ++S  +G +   FL++ A+QL+++GL  L    KE EL VF
Subjt:  PEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEVVLAEQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVF

Query:  FRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGDTLFMTSNFK-----EFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLN--SDL
        FRNNHFSTM K  G LYLL TDQG++ +  +VWE L+ V GD  F  S+F+     +    + +  S  +   M    DYL ++   +  G      SDL
Subjt:  FRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGDTLFMTSNFK-----EFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLN--SDL

Query:  QLAIALQQQEFEQ-QPQRQNVQQPSSGGSSRLVVGPQ
        +LA  LQQ+E++Q Q Q+Q  QQPS+G        PQ
Subjt:  QLAIALQQQEFEQ-QPQRQNVQQPSSGGSSRLVVGPQ

A3KQS4 Ubiquitin carboxyl-terminal hydrolase MINDY-1

4.1e-18

30.56

Show/hide

Query:  SSSSSEEPQNQPPQEQQQHLV------KEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE------
        SS+ S    NQ   ++ +  V       E      Y  K I +  + T ++ Q++NGPCPL+AI N+LLLR  +   +    V+ E+L++ + E      
Subjt:  SSSSSEEPQNQPPQEQQQHLV------KEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE------

Query:  -------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPCN
                                              + DFE+TPEC +FDLLDIPLYHGW+VDPQ  E  SA+   SYN ++E+++  E +H  D   
Subjt:  -------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPCN

Query:  NPEDDCIDFVAATTAT
          E    +    +TAT
Subjt:  NPEDDCIDFVAATTAT

Q2KJ22 Ubiquitin carboxyl-terminal hydrolase MINDY-1

9.7e-20

Show/hide

Query:  QGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGDTLFMTSNF----KEFKVESPSN
        +G +   FL+  A+QLT++GL  L    KE EL VFFRNNHFSTM K  G LYLL TDQG++ +  +VWE L+ V+GD+ F  S+F       K      
Subjt:  QGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGDTLFMTSNF----KEFKVESPSN

Query:  ESWDEHNAMTSTADYLASIDATKH----TGMDLNSDLQLAIALQQQEFEQQPQRQ
         S           DYL ++   +      G    SDL+LA  LQQ+E++Q    Q
Subjt:  ESWDEHNAMTSTADYLASIDATKH----TGMDLNSDLQLAIALQQQEFEQQPQRQ

Q2KJ22 Ubiquitin carboxyl-terminal hydrolase MINDY-1

1.1e-18

32.68

Show/hide

Query:  YKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE-----------------------------------------
        Y  K I + G  TPI+ Q+ NGPCPL+AI N+L L+  + L      ++ ++L++ + +                                         
Subjt:  YKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE-----------------------------------------

Query:  --RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELV
           + DFE+TPEC++FDLL IPLYHGW+VDPQ  E  SA+   SYN ++E+++
Subjt:  --RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELV

Q5BJQ2 Ubiquitin carboxyl-terminal hydrolase MINDY-1

8.8e-21

37.5

Show/hide

Query:  QGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGDTLFMTSNF----KEFKVESPSN
        +G +   FL+  A+QLT++GL  L    KE EL VFFRNNHFSTM K    LYLL TDQG++ +  +VWE L+ V+GD+ F  S+F       K      
Subjt:  QGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGDTLFMTSNF----KEFKVESPSN

Query:  ESWDEHNAMTSTADYLASIDATKH---TGMDLNSDLQLAIALQQQEFEQQPQRQNVQ-----QPSSGGSSRLVVGPQMVKSQLD
         S      +    DYL ++   +     GM   SDL+LA  LQQ+E++QQ   Q V+      P  G +S    G +  +S+ +
Subjt:  ESWDEHNAMTSTADYLASIDATKH---TGMDLNSDLQLAIALQQQEFEQQPQRQNVQ-----QPSSGGSSRLVVGPQMVKSQLD

Q5BJQ2 Ubiquitin carboxyl-terminal hydrolase MINDY-1

2.7e-17

30.77

Show/hide

Query:  SSSSSEEPQNQPPQEQQQHLVKEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE------------
        S   + E  ++P Q  Q   +++ + +  Y  K I + G  TPI+ Q+ NGPCPLLAI N+L L+  + L      ++ ++LL+ +              
Subjt:  SSSSSEEPQNQPPQEQQQHLVKEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE------------

Query:  -------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELV
                                        + DFE+TPEC++FDLL +PLYHGW+VDPQ  E  SA+   SYN ++E+++
Subjt:  -------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELV

Q6PDI6 Ubiquitin carboxyl-terminal hydrolase MINDY-2

3.3e-20

40.36

Show/hide

Query:  QGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGDTLFMTSNFKEFKVESPSN-ESW
        +G +   FL N A+QLT++GL  L   ++E ELCVFFRNNHFSTM K  GQLYLL TDQG++ +  +VWE L+ V+GD  F  S   EF +  PS+ E+ 
Subjt:  QGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGDTLFMTSNFKEFKVESPSN-ESW

Query:  DEHNAMTSTADYLASID-ATKHTGMDLN--------SDLQLAIALQQQE-------FEQQPQRQNV
         +        DYL ++    +    ++N        SDL+LA  LQ++E       +++Q Q Q V
Subjt:  DEHNAMTSTADYLASID-ATKHTGMDLN--------SDLQLAIALQQQE-------FEQQPQRQNV

Q6PDI6 Ubiquitin carboxyl-terminal hydrolase MINDY-2

1.8e-18

33.53

Show/hide

Query:  QEQQQHLVKEKEK---ECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAERIDD------------------
        ++  Q L   KE+   + VY  K IQ+    TPI+ QN+NGPCPLLAI NVLLL   + L      ++ E+L+  + + + +                  
Subjt:  QEQQQHLVKEKEK---ECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAERIDD------------------

Query:  -------------------------FEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVA
                                 FE+TPEC +FDLLDIPLYHGW+VDPQ  +   A+ + SYN ++E++++
Subjt:  -------------------------FEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVA

Q8NBR6 Ubiquitin carboxyl-terminal hydrolase MINDY-2

5.7e-20

38.69

Show/hide

Query:  QGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGDTLFMTSNFKEFKVESPSN-ESW
        +G +   FL N A+QLT++GL  L   ++E ELCVFFRNNHFSTM K  GQLYLL TDQG++ +  +VWE L+ V+GD  F  S   EF +  PS+ E+ 
Subjt:  QGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGDTLFMTSNFKEFKVESPSN-ESW

Query:  DEHNAMTSTADYLASID-ATKHTGMDLN--------SDLQLAIALQQQEFEQQPQRQNVQQPSSGGSS
         +        DYL ++    +    ++N        SDL+LA  LQ++E  +  Q    Q+ ++  ++
Subjt:  DEHNAMTSTADYLASID-ATKHTGMDLN--------SDLQLAIALQQQEFEQQPQRQNVQQPSSGGSS

Q8NBR6 Ubiquitin carboxyl-terminal hydrolase MINDY-2

2.8e-19

34.68

Show/hide

Query:  QEQQQHLVKEKEK---ECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAERIDD------------------
        +E  Q L   KE+   + VY  K IQ+    TPI+ QN+NGPCPLLAI NVLLL   + L      ++ E+L+  + + + D                  
Subjt:  QEQQQHLVKEKEK---ECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAERIDD------------------

Query:  -------------------------FEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVA
                                 FE+TPEC +FDLLDIPLYHGW+VDPQ  +   A+ + SYN ++E++++
Subjt:  -------------------------FEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVA

Arabidopsis top hits

e value

%identity

Alignment

AT4G11860.1 Protein of unknown function (DUF544)

2.4e-146

47.87

Show/hide

Query:  MASSSSSEEP--QNQPPQE--QQQHLVKE--KEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE----
        MA++SSSE P  + Q  QE  QQQ L KE   E+E +YKTK IQFLGR TPI+LQN+NGPCPLLAICNVLLLRNNLNL  D  EVSQE+L+SLV +    
Subjt:  MASSSSSEEP--QNQPPQE--QQQHLVKE--KEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAE----

Query:  -----------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHME
                                                 RIDDFEFTPECAIFDLLDIPLYHGWIVDPQD E A+AI SKSYNA+M ELVALETQ++E
Subjt:  -----------------------------------------RIDDFEFTPECAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHME

Query:  -DPCNNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKV
             NP +D +DF AATTA LGVPSP LSK RSFD+SP + ++ ++MRKGDLEEE ELL+AL+LS+ +      N    S   D+     D  P+   +
Subjt:  -DPCNNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPILMANHGVVSAEGDTNPIKLDEEPSPEKV

Query:  SVIDAVEKTIVKDICAADNNLNQQSDSSIVDSGK--TSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICPVEKDNHETLIETVTSSG
        + I  +++    D  A++N      D +++  GK  T+++   ED++      +Q SS                +S G   C VE            SS 
Subjt:  SVIDAVEKTIVKDICAADNNLNQQSDSSIVDSGK--TSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICPVEKDNHETLIETVTSSG

Query:  RDGALVNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGS-EPIYEGEECILDPRSTVLEDREPVY
        ++  +   SSE+ S   DK    +A        V K D    + + P ++C      + Q  +AP      V + EP+YEGEEC+ +    V  D+EPVY
Subjt:  RDGALVNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGS-EPIYEGEECILDPRSTVLEDREPVY

Query:  EGEVVLAEQGCGSSINFCNTQSKVE--ISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVW
        EGE +L ++     +  C+++ +    ++ ++GELIRNF+KN+ASQLTF GLF LQ+GLKERELCVFFRNNHF TMFK +G+LYLLATDQGY++QPDLVW
Subjt:  EGEVVLAEQGCGSSINFCNTQSKVE--ISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVW

Query:  EKLNEVNGDTLFMTSNFKEFKVESP---SNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQN-VQQPSSGGSSRLVVGPQ
        EKLNEVNGDT FMT+ FK+F ++S    ++ +WDE NA+T+TADYLASI+     G+D+NSDLQLAIALQQQEFE Q  R N   QP+S  +SRLV GPQ
Subjt:  EKLNEVNGDTLFMTSNFKEFKVESP---SNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQN-VQQPSSGGSSRLVVGPQ

Query:  MVKS
        + +S
Subjt:  MVKS

AT4G22960.1 Protein of unknown function (DUF544)

2.1e-49

29.52

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Query:  ECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVA----------------------------ERIDDFEFTPE
        E  YKTK I + G+   I+LQ+ NGPCPL+AICNVL+L++ +NL +  ++VS+E L++LV                             ERI DFE TPE
Subjt:  ECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVA----------------------------ERIDDFEFTPE

Query:  CAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPCNNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGD
          IF  L IPLYHGW+VDP D E  +AI  +S + +   L  L+TQ +           +DF AA+   LG                        + KGD
Subjt:  CAIFDLLDIPLYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPCNNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGD

Query:  LEEEAELLKALKLSETETPI--LMANHGVVSAEGDTNPIKLDEEPSPEKVSVIDAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNA
        +EE+  + KAL LSE E  +        VVS   D N I  +++     V +      T+  +IC                     LSK D+  S    +
Subjt:  LEEEAELLKALKLSETETPI--LMANHGVVSAEGDTNPIKLDEEPSPEKVSVIDAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNA

Query:  TEQASSSSQLKTDAGKHLDQTAESEGYKICPVEKDNHETL--IETVTSSGRDGALVN-ESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTV
        TE        KT+ G+ +  T   +            ET   +ET  SS     L++ E +   S  ND                          +S  +
Subjt:  TEQASSSSQLKTDAGKHLDQTAESEGYKICPVEKDNHETL--IETVTSSGRDGALVN-ESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTV

Query:  TCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEVVLAEQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGL
        T  +++                             L  +S   +  + VYE + +L +    SS     T+    ++ ++GELI+ F + + +QLT++GL
Subjt:  TCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLEDREPVYEGEVVLAEQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGL

Query:  FCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGDTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHT
        F L+D LKE ELCV FRNNHF+TM + + +LY L T +GY  Q DLVWE+ N+++GD+ F T  F +F  +       D+ +A++ T +   SI   K  
Subjt:  FCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVNGDTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHT

Query:  GMDLNS-DLQLAIALQQQEF
         MD    D  LA+ L+Q ++
Subjt:  GMDLNS-DLQLAIALQQQEF

Sequences

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CDS sequence

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ATGGCGTCGTCTTCTTCCTCTGAAGAACCTCAAAATCAACCACCACAAGAACAGCAGCAACACCTGGTGAAGGAGAAGGAAAAGGAGTGCGTATACAAGACCAAACCCAT
TCAATTTCTCGGTCGCCCTACGCCTATTGTCCTCCAGAACGATAATGGCCCTTGCCCTCTCCTCGCCATATGTAATGTTCTCTTGTTGCGGAACAACTTAAATTTGGGTT
CAGATGCTACTGAAGTATCACAGGAAAAATTGTTATCTCTGGTTGCTGAACGGATTGATGATTTTGAATTCACTCCAGAATGTGCAATTTTTGATTTGCTGGATATTCCT
CTATATCATGGTTGGATAGTTGATCCTCAGGATCACGAAACTGCTAGTGCAATTGATTCCAAGTCCTACAATGCTATTATGGAGGAGCTTGTTGCTCTGGAAACGCAACA
CATGGAGGATCCGTGTAACAATCCTGAAGATGATTGTATTGATTTTGTAGCTGCAACAACAGCCACGCTTGGAGTCCCGTCTCCAAATCTTTCAAAAGTTCGATCTTTTG
ATGAATCACCTTGTTCAATCTCTGATGAGCAACAAATGAGAAAAGGAGATCTTGAAGAAGAGGCAGAGTTATTGAAAGCCTTGAAATTGTCTGAAACTGAAACACCAATC
TTAATGGCTAATCATGGAGTGGTCAGTGCTGAGGGGGACACTAACCCTATTAAATTGGATGAGGAGCCATCTCCGGAGAAGGTTTCGGTCATAGATGCTGTGGAGAAGAC
CATAGTAAAAGACATCTGTGCTGCAGACAATAATCTTAACCAGCAGTCAGATTCATCCATTGTAGATTCTGGCAAGACCTCATTGAGCAAGAGTGATGAAGATGTGTCAC
CTTTTCCCAATGCCACAGAGCAAGCAAGCTCTTCTTCACAATTGAAGACTGATGCGGGAAAGCACCTTGATCAGACTGCTGAGTCTGAAGGGTATAAGATTTGCCCTGTG
GAGAAGGACAATCATGAAACATTGATCGAGACTGTCACCAGTTCTGGAAGAGATGGTGCATTGGTGAATGAGAGTTCTGAGAGTAATTCGCAAATGAATGATAAATGCCC
TTTTCCAGCTGCTTGTGAAACAGTTGATCATAGACCAGTTGATAAGGAAGACCCAATTGAACTATCAGGGCTATCTCCGACTGTTACTTGTACAGATTCAGAAGGTGGTA
AAATCCAATGTATTGAGGCACCTGAAGGTTTGACTTCAACTGTTGGTAGTGAGCCCATATATGAAGGTGAGGAATGTATACTGGATCCAAGAAGTACAGTTCTTGAAGAT
CGAGAGCCCGTATATGAAGGTGAAGTTGTTCTTGCGGAACAGGGTTGTGGAAGCTCCATAAATTTCTGTAATACACAGTCAAAGGTTGAAATCAGTCCAAAACAAGGGGA
GCTGATCAGGAATTTTTTAAAGAACAATGCAAGCCAGCTAACTTTTTATGGCCTTTTCTGCTTACAAGATGGTCTGAAAGAGCGTGAGCTTTGTGTTTTCTTCCGTAATA
ATCACTTCAGCACCATGTTTAAGCTTGATGGCCAGCTTTATCTCTTAGCTACAGACCAAGGTTACATTCATCAACCTGACTTGGTGTGGGAAAAGCTAAATGAGGTAAAT
GGAGACACATTATTTATGACGAGTAATTTCAAAGAATTCAAAGTAGAAAGTCCTTCAAATGAGTCTTGGGATGAACATAATGCCATGACAAGCACAGCGGACTATCTTGC
AAGCATTGATGCTACCAAACATACCGGAATGGATTTGAATTCTGACCTGCAATTAGCAATAGCCCTGCAACAGCAAGAGTTTGAACAACAACCACAGCGACAAAATGTGC
AGCAGCCATCTTCAGGCGGCAGTTCAAGGCTGGTCGTGGGTCCTCAGATGGTTAAGTCTCAACTGGATCTGTGCCCGGGGTACCCTAAAAAACGTTACGAATATGGGTCT
TTATGTGCTGGTTTGAGTTGA

mRNA sequence

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Protein sequence

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MASSSSSEEPQNQPPQEQQQHLVKEKEKECVYKTKPIQFLGRPTPIVLQNDNGPCPLLAICNVLLLRNNLNLGSDATEVSQEKLLSLVAERIDDFEFTPECAIFDLLDIP
LYHGWIVDPQDHETASAIDSKSYNAIMEELVALETQHMEDPCNNPEDDCIDFVAATTATLGVPSPNLSKVRSFDESPCSISDEQQMRKGDLEEEAELLKALKLSETETPI
LMANHGVVSAEGDTNPIKLDEEPSPEKVSVIDAVEKTIVKDICAADNNLNQQSDSSIVDSGKTSLSKSDEDVSPFPNATEQASSSSQLKTDAGKHLDQTAESEGYKICPV
EKDNHETLIETVTSSGRDGALVNESSESNSQMNDKCPFPAACETVDHRPVDKEDPIELSGLSPTVTCTDSEGGKIQCIEAPEGLTSTVGSEPIYEGEECILDPRSTVLED
REPVYEGEVVLAEQGCGSSINFCNTQSKVEISPKQGELIRNFLKNNASQLTFYGLFCLQDGLKERELCVFFRNNHFSTMFKLDGQLYLLATDQGYIHQPDLVWEKLNEVN
GDTLFMTSNFKEFKVESPSNESWDEHNAMTSTADYLASIDATKHTGMDLNSDLQLAIALQQQEFEQQPQRQNVQQPSSGGSSRLVVGPQMVKSQLDLCPGYPKKRYEYGS
LCAGLS

HG10009196 (gene) of Bottle gourd (Hangzhou Gourd) v1 genome