CuGenDBv2

Gene ID	HG10009452
Organism	Lagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
Description	protein phosphatase inhibitor 2
Genome location	Chr06:6110623..6114621
RNA-Seq Expression	HG10009452
Synteny	HG10009452
Gene Ontology terms	GO:0009966 - regulation of signal transduction (biological process) GO:0043086 - negative regulation of catalytic activity (biological process) GO:0043666 - regulation of phosphoprotein phosphatase activity (biological process) GO:0004864 - protein phosphatase inhibitor activity (molecular function)
InterPro domains	IPR007062 - Protein phosphatase inhibitor 2 (IPP-2)

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAA0055165.1 protein phosphatase inhibitor 2 [Cucumis melo var. makuwa]

4.7e-83

90.66

Show/hide

Query:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEAD
        MS KESKSG  RHVKWDE NIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVR+ FDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDE+D
Subjt:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEAD

Query:  AMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGKGVRNIDIEKKNKGNFSQQSPPPANGVGG
        AMDQD+EDK +LSFKEHRRAHYDEFRKIRELRRNGSLLVD+DDEDDVEMDMMGKGVR+IDIEKKNKG+ SQ S PP NGVGG
Subjt:  AMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGKGVRNIDIEKKNKGNFSQQSPPPANGVGG

XP_004143631.1 protein phosphatase inhibitor 2 isoform X1 [Cucumis sativus]

8.9e-82

90.11

Show/hide

Query:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEAD
        MS KESKSG  RHVKWDE NIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRD FDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDE+D
Subjt:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEAD

Query:  AMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGKGVRNIDIEKKNKGNFSQQSPPPANGVGG
        AMDQD+EDK +LSFKEHRRAHYDEFRKIRELRRNGSLLVD+DDEDDVEMDMMGKGVR+IDIEKKNKG+  Q S P  NGVGG
Subjt:  AMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGKGVRNIDIEKKNKGNFSQQSPPPANGVGG

XP_008467230.1 PREDICTED: protein phosphatase inhibitor 2 [Cucumis melo]

4.7e-83

90.66

Show/hide

Query:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEAD
        MS KESKSG  RHVKWDE NIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVR+ FDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDE+D
Subjt:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEAD

Query:  AMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGKGVRNIDIEKKNKGNFSQQSPPPANGVGG
        AMDQD+EDK +LSFKEHRRAHYDEFRKIRELRRNGSLLVD+DDEDDVEMDMMGKGVR+IDIEKKNKG+ SQ S PP NGVGG
Subjt:  AMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGKGVRNIDIEKKNKGNFSQQSPPPANGVGG

XP_031741140.1 protein phosphatase inhibitor 2 isoform X2 [Cucumis sativus]

5.4e-79

90.29

Show/hide

Query:  SGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEADAMDQDDE
        SG  RHVKWDE NIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRD FDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDE+DAMDQD+E
Subjt:  SGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEADAMDQDDE

Query:  DKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGKGVRNIDIEKKNKGNFSQQSPPPANGVGG
        DK +LSFKEHRRAHYDEFRKIRELRRNGSLLVD+DDEDDVEMDMMGKGVR+IDIEKKNKG+  Q S P  NGVGG
Subjt:  DKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGKGVRNIDIEKKNKGNFSQQSPPPANGVGG

XP_038874678.1 protein phosphatase inhibitor 2 isoform X1 [Benincasa hispida]

2.6e-89

94.51

Show/hide

Query:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEAD
        MS KESKSG  RHVKWDE NIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFD+CVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEAD
Subjt:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEAD

Query:  AMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGKGVRNIDIEKKNKGNFSQQSPPPANGVGG
        AMDQDDEDK +LSFKEHRRAHYDEFRKIRELRRNGS+LVD+DDEDDVEMDMMGKGVR+IDIEKKNKGNFSQQSPPPANGVGG
Subjt:  AMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGKGVRNIDIEKKNKGNFSQQSPPPANGVGG

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KLC2 Uncharacterized protein

4.3e-82

90.11

Show/hide

Query:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEAD
        MS KESKSG  RHVKWDE NIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRD FDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDE+D
Subjt:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEAD

Query:  AMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGKGVRNIDIEKKNKGNFSQQSPPPANGVGG
        AMDQD+EDK +LSFKEHRRAHYDEFRKIRELRRNGSLLVD+DDEDDVEMDMMGKGVR+IDIEKKNKG+  Q S P  NGVGG
Subjt:  AMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGKGVRNIDIEKKNKGNFSQQSPPPANGVGG

A0A1S3CT19 protein phosphatase inhibitor 2

2.3e-83

90.66

Show/hide

Query:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEAD
        MS KESKSG  RHVKWDE NIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVR+ FDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDE+D
Subjt:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEAD

Query:  AMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGKGVRNIDIEKKNKGNFSQQSPPPANGVGG
        AMDQD+EDK +LSFKEHRRAHYDEFRKIRELRRNGSLLVD+DDEDDVEMDMMGKGVR+IDIEKKNKG+ SQ S PP NGVGG
Subjt:  AMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGKGVRNIDIEKKNKGNFSQQSPPPANGVGG

A0A5D3BMG4 Protein phosphatase inhibitor 2

2.3e-83

90.66

Show/hide

Query:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEAD
        MS KESKSG  RHVKWDE NIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVR+ FDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDE+D
Subjt:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEAD

Query:  AMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGKGVRNIDIEKKNKGNFSQQSPPPANGVGG
        AMDQD+EDK +LSFKEHRRAHYDEFRKIRELRRNGSLLVD+DDEDDVEMDMMGKGVR+IDIEKKNKG+ SQ S PP NGVGG
Subjt:  AMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGKGVRNIDIEKKNKGNFSQQSPPPANGVGG

A0A6J1H2I0 protein phosphatase inhibitor 2-like

3.0e-75

80.73

Show/hide

Query:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVA-SSSGKSSQRSSGWTSSEDEA
        MS KESKSG  R VKWDE NIG IEANKPVRQKITEPKTPYHPMIDDD+SLSPVRDRFDLCVGDAMHAEAIRTALNDVA SSSGKSSQRSSGWTSSEDEA
Subjt:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVA-SSSGKSSQRSSGWTSSEDEA

Query:  DAMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGK---------GVRNIDIEKKNKGNFSQQSPPPANGVGG
        DAMDQDDEDK +LSFKEHRRAHYDEFRK+REL RNGSLLV++DD++++EMD+  +         GV++I IEKK+K NFSQQSP PANGVGG
Subjt:  DAMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGK---------GVRNIDIEKKNKGNFSQQSPPPANGVGG

A0A6J1JZT5 protein phosphatase inhibitor 2-like isoform X1

1.3e-75

81.25

Show/hide

Query:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVA-SSSGKSSQRSSGWTSSEDEA
        MS KESKSG  R VKWDE NIG IEANKPVRQKITEPKTPYHPMIDDD+SLSPVRDRFDLCVGDAMHAEAIRTALNDVA SSSGKSSQRSSGWTSSEDEA
Subjt:  MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVA-SSSGKSSQRSSGWTSSEDEA

Query:  DAMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDM---------MGKGVRNIDIEKKNKGNFSQQSPPPANGVGG
        DAMDQDDEDK +LSFKEHRRAHYDEFRK+REL RNGSLLV++DD+++VEMD+         +  GV++I IEKK+K NFSQQSP PANGVGG
Subjt:  DAMDQDDEDKTSLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDM---------MGKGVRNIDIEKKNKGNFSQQSPPPANGVGG

SwissProt top hits

e value

%identity

Alignment

Q9LTK0 Protein phosphatase inhibitor 2

1.1e-34

49.44

Show/hide

Query:  VKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSS---GWTSS---EDEADAMDQDDE
        V+WDE NI +IE+NKPVRQKITEPKTPYHPM+DDD SLSP    FD CV D   AE +R  LND A+SS ++S + S   GW+SS   E+EAD MDQD+E
Subjt:  VKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSS---GWTSS---EDEADAMDQDDE

Query:  DKTS---LSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGK----------GVRNIDIEKKNKGNFSQQSP
           S     F  HR+AHYDEFRK++ELR +GS   ++++EDD       +          G + +D  K   G  S  SP
Subjt:  DKTS---LSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGK----------GVRNIDIEKKNKGNFSQQSP

Arabidopsis top hits

e value

%identity

Alignment

AT5G52200.1 phosphoprotein phosphatase inhibitors

7.9e-36

49.44

Show/hide

Query:  VKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSS---GWTSS---EDEADAMDQDDE
        V+WDE NI +IE+NKPVRQKITEPKTPYHPM+DDD SLSP    FD CV D   AE +R  LND A+SS ++S + S   GW+SS   E+EAD MDQD+E
Subjt:  VKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSS---GWTSS---EDEADAMDQDDE

Query:  DKTS---LSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGK----------GVRNIDIEKKNKGNFSQQSP
           S     F  HR+AHYDEFRK++ELR +GS   ++++EDD       +          G + +D  K   G  S  SP
Subjt:  DKTS---LSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGK----------GVRNIDIEKKNKGNFSQQSP

AT5G52200.2 phosphoprotein phosphatase inhibitors

7.9e-36

49.44

Show/hide

Query:  VKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSS---GWTSS---EDEADAMDQDDE
        V+WDE NI +IE+NKPVRQKITEPKTPYHPM+DDD SLSP    FD CV D   AE +R  LND A+SS ++S + S   GW+SS   E+EAD MDQD+E
Subjt:  VKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSS---GWTSS---EDEADAMDQDDE

Query:  DKTS---LSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGK----------GVRNIDIEKKNKGNFSQQSP
           S     F  HR+AHYDEFRK++ELR +GS   ++++EDD       +          G + +D  K   G  S  SP
Subjt:  DKTS---LSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGK----------GVRNIDIEKKNKGNFSQQSP

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGAGTAGAAAAGAATCAAAGAGTGGCTGCAGTCGCCATGTGAAATGGGATGAAGGTAATATTGGTCAAATTGAAGCAAATAAACCTGTGCGACAGAAAATTACCGAACC
TAAGACGCCTTATCATCCCATGATTGATGATGATGATTCTCTATCTCCTGTGCGGGACAGGTTTGATTTGTGTGTTGGTGATGCAATGCATGCAGAAGCGATTCGAACTG
CATTGAATGATGTGGCTTCCTCAAGTGGTAAAAGCAGCCAGCGATCTAGTGGTTGGACATCTTCTGAGGATGAAGCAGATGCCATGGACCAAGATGATGAAGACAAGACC
AGTTTGAGCTTTAAGGAGCACAGAAGAGCACACTACGATGAATTTAGGAAGATTAGAGAGCTCCGAAGGAATGGGTCGCTTTTAGTGGACGATGACGATGAAGACGATGT
TGAGATGGATATGATGGGGAAAGGTGTGAGGAATATTGATATTGAGAAAAAGAACAAGGGTAATTTTTCTCAACAATCACCTCCACCAGCCAATGGAGTTGGAGGTTGA

mRNA sequence

Show/hide mRNA sequence

Protein sequence

Show/hide protein sequence

MSRKESKSGCSRHVKWDEGNIGQIEANKPVRQKITEPKTPYHPMIDDDDSLSPVRDRFDLCVGDAMHAEAIRTALNDVASSSGKSSQRSSGWTSSEDEADAMDQDDEDKT
SLSFKEHRRAHYDEFRKIRELRRNGSLLVDDDDEDDVEMDMMGKGVRNIDIEKKNKGNFSQQSPPPANGVGG

HG10009452 (gene) of Bottle gourd (Hangzhou Gourd) v1 genome