CuGenDBv2

Gene ID	HG10012814
Organism	Lagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
Description	dCTP pyrophosphatase 1
Genome location	Chr01:24439639..24440246
RNA-Seq Expression	HG10012814
Synteny	HG10012814
Gene Ontology terms	GO:0006253 - dCTP catabolic process (biological process) GO:0042262 - DNA protection (biological process) GO:0005829 - cytosol (cellular component) GO:0000287 - magnesium ion binding (molecular function) GO:0047840 - dCTP diphosphatase activity (molecular function)
InterPro domains	IPR004518 - NTP pyrophosphohydrolase MazG, putative catalytic core IPR025984 - dCTP pyrophosphatase 1

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0049237.1 dCTP pyrophosphatase 1-like [Cucumis melo var. makuwa]

1.3e-52

93.1

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Query:  MGGGKQVDITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP
        MGGGKQVD  VDDISLKDLS KLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGL DWEESDKEHLGEELSDVLLYLIRLADICGINL 
Subjt:  MGGGKQVDITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP

Query:  DAATKKLIKNSIKYPS
        +AATKKL+KNSIKYP+
Subjt:  DAATKKLIKNSIKYPS

XP_004134058.1 dCTP pyrophosphatase 1 [Cucumis sativus]

7.4e-53

91.53

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Query:  MGGGKQVD--ITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGIN
        MGGGKQVD  + VDDISLKDLS KLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGL DWEESDKEHLGEELSDVLLYLIRLADICGIN
Subjt:  MGGGKQVD--ITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGIN

Query:  LPDAATKKLIKNSIKYPS
        L +AATKKL+KNSIKYP+
Subjt:  LPDAATKKLIKNSIKYPS

XP_008438499.1 PREDICTED: dCTP pyrophosphatase 1-like [Cucumis melo]

5.7e-53

91.53

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Query:  MGGGKQVDIT--VDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGIN
        MGGGKQVD+   VDDISLKDLS KLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGL DWEESDKEHLGEELSDVLLYLIRLADICGIN
Subjt:  MGGGKQVDIT--VDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGIN

Query:  LPDAATKKLIKNSIKYPS
        L +AATKKL+KNSIKYP+
Subjt:  LPDAATKKLIKNSIKYPS

XP_022924788.1 dCTP pyrophosphatase 1-like [Cucurbita moschata]

1.8e-54

91.67

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Query:  MGGGKQVDITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP
        MGG +Q D+ V DISLKDLSSKLEEFAK RNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP
Subjt:  MGGGKQVDITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP

Query:  DAATKKLIKNSIKY--PSQP
        DAATKKL+KNSIKY  PSQP
Subjt:  DAATKKLIKNSIKY--PSQP

XP_038878506.1 dCTP pyrophosphatase 1-like [Benincasa hispida]

7.7e-58

97.44

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Query:  MGGGKQVDITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP
        MGGGKQVDI VDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP
Subjt:  MGGGKQVDITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP

Query:  DAATKKLIKNSIKYPSQ
        DAATKKL+KNSIKYP Q
Subjt:  DAATKKLIKNSIKYPSQ

TrEMBL top hits

e value

%identity

Alignment

A0A0A0L514 dCTP pyrophosphatase 1

3.6e-53

91.53

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Query:  MGGGKQVD--ITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGIN
        MGGGKQVD  + VDDISLKDLS KLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGL DWEESDKEHLGEELSDVLLYLIRLADICGIN
Subjt:  MGGGKQVD--ITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGIN

Query:  LPDAATKKLIKNSIKYPS
        L +AATKKL+KNSIKYP+
Subjt:  LPDAATKKLIKNSIKYPS

A0A1S3AW64 dCTP pyrophosphatase 1

2.8e-53

91.53

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Query:  MGGGKQVDIT--VDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGIN
        MGGGKQVD+   VDDISLKDLS KLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGL DWEESDKEHLGEELSDVLLYLIRLADICGIN
Subjt:  MGGGKQVDIT--VDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGIN

Query:  LPDAATKKLIKNSIKYPS
        L +AATKKL+KNSIKYP+
Subjt:  LPDAATKKLIKNSIKYPS

A0A5A7U4H7 dCTP pyrophosphatase 1

6.1e-53

93.1

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Query:  MGGGKQVDITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP
        MGGGKQVD  VDDISLKDLS KLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGL DWEESDKEHLGEELSDVLLYLIRLADICGINL 
Subjt:  MGGGKQVDITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP

Query:  DAATKKLIKNSIKYPS
        +AATKKL+KNSIKYP+
Subjt:  DAATKKLIKNSIKYPS

A0A6J1EDH1 dCTP pyrophosphatase 1

8.6e-55

91.67

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Query:  MGGGKQVDITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP
        MGG +Q D+ V DISLKDLSSKLEEFAK RNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP
Subjt:  MGGGKQVDITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP

Query:  DAATKKLIKNSIKY--PSQP
        DAATKKL+KNSIKY  PSQP
Subjt:  DAATKKLIKNSIKY--PSQP

A0A6J1IR36 dCTP pyrophosphatase 1

8.6e-55

91.67

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Query:  MGGGKQVDITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP
        MGG +Q D+ V DISLKDLSSKLEEFAK RNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP
Subjt:  MGGGKQVDITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP

Query:  DAATKKLIKNSIKY--PSQP
        DAATKKL+KNSIKY  PSQP
Subjt:  DAATKKLIKNSIKY--PSQP

SwissProt top hits

e value

%identity

Alignment

Q32KY6 dCTP pyrophosphatase 1

2.4e-22

48.51

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Query:  SLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLPDAATKKLIKNSIKY
        +L+D+     EFA  R+WE++H PRNLLLA+VGEVGEL+E+FQW+ + E G   W   ++  L EELSD+L+YL+ LA  C ++LP A   K+  N  +Y
Subjt:  SLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLPDAATKKLIKNSIKY

Query:  P
        P
Subjt:  P

Q91VC0 dCTP pyrophosphatase 1

2.2e-23

49.5

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Query:  SLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLPDAATKKLIKNSIKY
        +L+D+     EFA  R+WE++H PRNLLLA+VGEVGEL+E+FQW+ + E G   W+  ++  L EELSDVL+YL+ LA  C ++LP A   K+  N  +Y
Subjt:  SLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLPDAATKKLIKNSIKY

Query:  P
        P
Subjt:  P

Q9H773 dCTP pyrophosphatase 1

3.2e-22

49.02

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Query:  SLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLPDAATKKLIKNSIKY
        +L+D+     EFA  R+WE++H PRNLLLA+VGEVGEL+E+FQW+ + E G   W   ++  L EELSDVL+YL+ LA  C ++LP A   K+  N  +Y
Subjt:  SLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLPDAATKKLIKNSIKY

Query:  PS
        P+
Subjt:  PS

Q9QY93 dCTP pyrophosphatase 1

2.9e-23

49.5

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Query:  SLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLPDAATKKLIKNSIKY
        +L+D+     EFA  R+WE++H PRNLLLA+VGEVGEL+E+FQW+ + E G   W   ++  L EELSDVL+YL+ LA  C ++LP A   K+  N  +Y
Subjt:  SLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLPDAATKKLIKNSIKY

Query:  P
        P
Subjt:  P

Arabidopsis top hits

e value

%identity

Alignment

AT3G25400.1 CONTAINS InterPro DOMAIN/s: NTP Pyrophosphohydrolase MazG-related, RS21-C6 (InterPro:IPR011394), EAR (InterPro:IPR009039), NTP pyrophosphohydrolase MazG, putative catalytic core (InterPro:IPR004518); Has 1123 Blast hits to 1121 proteins in 452 species: Archae - 22; Bacteria - 753; Metazoa - 81; Fungi - 3; Plants - 83; Viruses - 0; Other Eukaryotes - 181 (source: NCBI BLink).

2.6e-40

65.22

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Query:  MGGGKQVDITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP
        M  G++     + +SL+ LS K+++FAKAR+WEKYHSPRNLLLAMVGEVGELSEIFQW+GEV +G PDW+E +K HLGEELSDVLLYL+RL+D CG++L 
Subjt:  MGGGKQVDITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLP

Query:  DAATKKLIKNSIKYP
         AA +K+  N+IKYP
Subjt:  DAATKKLIKNSIKYP

Sequences

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CDS sequence

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ATGGGAGGGGGCAAGCAGGTCGATATCACGGTCGACGACATTAGCCTCAAGGACCTCTCGTCCAAGCTCGAGGAGTTTGCCAAGGCCAGAAATTGGGAGAAGTATCATAG
TCCTAGAAACCTTCTCCTTGCCATGGTAGGAGAAGTAGGGGAGCTATCAGAAATATTCCAATGGAGAGGGGAAGTGGAGAAAGGGCTGCCAGATTGGGAGGAATCAGATA
AAGAGCATCTTGGGGAAGAACTTTCTGATGTGTTGCTTTATCTTATCAGATTGGCTGATATTTGTGGAATCAATCTGCCTGATGCTGCAACTAAGAAGCTTATTAAGAAC
TCCATCAAATACCCATCCCAACCCCAATAG

mRNA sequence

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Protein sequence

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MGGGKQVDITVDDISLKDLSSKLEEFAKARNWEKYHSPRNLLLAMVGEVGELSEIFQWRGEVEKGLPDWEESDKEHLGEELSDVLLYLIRLADICGINLPDAATKKLIKN
SIKYPSQPQ

HG10012814 (gene) of Bottle gourd (Hangzhou Gourd) v1 genome