CuGenDBv2

Gene ID	HG10018593
Organism	Lagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
Description	AIR carboxylase
Genome location	Chr04:5598444..5600143
RNA-Seq Expression	HG10018593
Synteny	HG10018593
Gene Ontology terms	GO:0006189 - 'de novo' IMP biosynthetic process (biological process) GO:0004638 - phosphoribosylaminoimidazole carboxylase activity (molecular function) GO:0005524 - ATP binding (molecular function) GO:0043727 - 5-amino-4-imidazole carboxylate lyase activity (molecular function) GO:0046872 - metal ion binding (molecular function)
InterPro domains	IPR000031 - PurE domain IPR024694 - PurE, prokaryotic type IPR033747 - Class I PurE

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAA0037050.1 phosphoribosylaminoimidazole carboxylase [Cucumis melo var. makuwa]

1.6e-71

93.08

Show/hide

Query:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
        MGSDSDFPVMRDAAKVLDTF VPYEIKIVSAHRTPDWMFSYASSAQERGI++IIAGAG      GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
Subjt:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG

Query:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
        VPVATVAINNATNAG LAVRMLGVAD DLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
Subjt:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ

KAG7033417.1 Phosphoribosylaminoimidazole carboxylase, chloroplastic, partial [Cucurbita argyrosperma subsp. argyrosperma]

1.2e-71

95.42

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Query:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAGGMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRGVPVATV
        MGSDSDFPVMRDAAKVLDTF  PYEIKIVSAHRTP WMFSYASSAQERGIQIIIAGAGGMVASLTPLPVIGVPVRAS LDG+DSLLSIVQMPRGVPVATV
Subjt:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAGGMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRGVPVATV

Query:  AINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
        AINNATNAG LAVRMLGVAD DLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
Subjt:  AINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ

XP_008441168.1 PREDICTED: phosphoribosylaminoimidazole carboxylase, chloroplastic isoform X1 [Cucumis melo]

1.6e-71

93.08

Show/hide

Query:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
        MGSDSDFPVMRDAAKVLDTF VPYEIKIVSAHRTPDWMFSYASSAQERGI++IIAGAG      GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
Subjt:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG

Query:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
        VPVATVAINNATNAG LAVRMLGVAD DLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
Subjt:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ

XP_016899416.1 PREDICTED: phosphoribosylaminoimidazole carboxylase, chloroplastic isoform X2 [Cucumis melo]

1.6e-71

93.08

Show/hide

Query:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
        MGSDSDFPVMRDAAKVLDTF VPYEIKIVSAHRTPDWMFSYASSAQERGI++IIAGAG      GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
Subjt:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG

Query:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
        VPVATVAINNATNAG LAVRMLGVAD DLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
Subjt:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ

XP_016899417.1 PREDICTED: phosphoribosylaminoimidazole carboxylase, chloroplastic isoform X4 [Cucumis melo]

1.6e-71

93.08

Show/hide

Query:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
        MGSDSDFPVMRDAAKVLDTF VPYEIKIVSAHRTPDWMFSYASSAQERGI++IIAGAG      GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
Subjt:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG

Query:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
        VPVATVAINNATNAG LAVRMLGVAD DLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
Subjt:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ

TrEMBL top hits

e value

%identity

Alignment

A0A1S3B3F9 AIR carboxylase

7.6e-72

93.08

Show/hide

Query:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
        MGSDSDFPVMRDAAKVLDTF VPYEIKIVSAHRTPDWMFSYASSAQERGI++IIAGAG      GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
Subjt:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG

Query:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
        VPVATVAINNATNAG LAVRMLGVAD DLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
Subjt:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ

A0A1S3B3J7 AIR carboxylase

7.6e-72

93.08

Show/hide

Query:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
        MGSDSDFPVMRDAAKVLDTF VPYEIKIVSAHRTPDWMFSYASSAQERGI++IIAGAG      GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
Subjt:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG

Query:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
        VPVATVAINNATNAG LAVRMLGVAD DLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
Subjt:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ

A0A1S4DTU3 AIR carboxylase

7.6e-72

93.08

Show/hide

Query:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
        MGSDSDFPVMRDAAKVLDTF VPYEIKIVSAHRTPDWMFSYASSAQERGI++IIAGAG      GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
Subjt:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG

Query:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
        VPVATVAINNATNAG LAVRMLGVAD DLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
Subjt:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ

A0A1S4DTU8 AIR carboxylase

7.6e-72

93.08

Show/hide

Query:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
        MGSDSDFPVMRDAAKVLDTF VPYEIKIVSAHRTPDWMFSYASSAQERGI++IIAGAG      GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
Subjt:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG

Query:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
        VPVATVAINNATNAG LAVRMLGVAD DLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
Subjt:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ

A0A5D3C3X4 AIR carboxylase

7.6e-72

93.08

Show/hide

Query:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
        MGSDSDFPVMRDAAKVLDTF VPYEIKIVSAHRTPDWMFSYASSAQERGI++IIAGAG      GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
Subjt:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG

Query:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
        VPVATVAINNATNAG LAVRMLGVAD DLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ
Subjt:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ

SwissProt top hits

e value

%identity

Alignment

O58058 N5-carboxyaminoimidazole ribonucleotide mutase

6.9e-46

57.96

Show/hide

Query:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
        MGSDSD PVM++AA++L+ F VPYEI I+SAHRTP+  + YA  A+ERGI++IIAGAG      G++ASLT LPVIGVP+++ AL+GLDSLLSIVQMP G
Subjt:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG

Query:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWD
        +PVATVAI+NA NA  LA+R+LG+  P++  ++ ++ +D K+ V  KA++LE+ GW+
Subjt:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWD

O74197 Phosphoribosylaminoimidazole carboxylase

2.6e-45

62.42

Show/hide

Query:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
        MGSDSD PVM  A K+L+ F+VP+E+ IVSAHRTP  M  YAS A  RGI++IIAGAG      GMVA++TP+PVIGVPV+ S LDG+DSL SIVQMPRG
Subjt:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG

Query:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWD
        VPVATVAINN+TNAG LAVRMLG+ + D + +M +F    ++ VL KA KLE  G++
Subjt:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWD

P15567 Phosphoribosylaminoimidazole carboxylase

4.8e-47

64.1

Show/hide

Query:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
        MGSDSD   M+DAA +LD F VPYE+ IVSAHRTPD M +YA +A  RG+++IIAGAG      GMVA++TPLPVIGVPV+ S LDG+DSL SIVQMPRG
Subjt:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG

Query:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGW
        VPVATVAINN+ NAG LA R+L    P LL+ M  F ++ K+ VL KA+KLEK GW
Subjt:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGW

P55195 Phosphoribosylaminoimidazole carboxylase, chloroplastic (Fragment)

1.3e-57

73.89

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Query:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
        MGSDSD PVM+ AA++++ F VP+E++IVSAHRTP+ MF YASSA ERG Q+IIAGAG      GMVASLTPLPV+GVPVRAS LDGLDSLLSIVQMPRG
Subjt:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG

Query:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWD
        VPVATVA+NNATNAG LAVRMLGVA+ +LLSRMSQ+QED K+ VL + +KLEK GW+
Subjt:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWD

Q9WYS7 N5-carboxyaminoimidazole ribonucleotide mutase

5.3e-46

61.54

Show/hide

Query:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
        MGSDSD PVM+ AA++L+ F + YEI IVSAHRTPD MF YA +A+ERGI++IIAGAG      GMVAS+T LPVIGVPV+ S L+GLDSL SIVQMP G
Subjt:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG

Query:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGW
        VPVATVAINNA NAG LA  +LG+  P++  ++ +++E  K+ VL KA++LE+ G+
Subjt:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGW

Arabidopsis top hits

e value

%identity

Alignment

AT2G05140.1 phosphoribosylaminoimidazole carboxylase family protein / AIR carboxylase family protein

1.7e-55

70.06

Show/hide

Query:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
        MGSD+D  VM+DAAK+LD F V +E+KIVSAHRTP+ M++YA+SA  RG+Q+IIAGAG      GMVASLTPLPVIGVPV+A+ LDG+DSLLSIVQMPRG
Subjt:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG

Query:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWD
        VPVATVAINNATNA  LAVRMLG++D DL+SRM Q+QED +   L+K EKLE  GW+
Subjt:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWD

AT2G37690.1 phosphoribosylaminoimidazole carboxylase, putative / AIR carboxylase, putative

1.8e-57

71.34

Show/hide

Query:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG
        MGSD+D PVM+DAAK+LD F V +E+KIVSAHRTP+ M++YA+SA  RG+Q+IIAGAG      GMVASLTPLPVIGVPVRA+ LDG+DSLLSIVQMPRG
Subjt:  MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAG------GMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRG

Query:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWD
        VPVATVAINNATNA  LAVRMLG++D DL+SRM Q+QED +   L+K EKLE +GW+
Subjt:  VPVATVAINNATNAGSLAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWD

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGGGCTCTGATTCGGATTTTCCTGTAATGAGAGATGCTGCAAAGGTCCTTGACACGTTTGATGTGCCTTATGAGATAAAGATAGTTTCTGCACATCGGACCCCCGATTG
GATGTTTTCTTACGCGTCATCCGCTCAGGAGAGAGGGATACAGATTATCATTGCGGGTGCTGGGGGTATGGTTGCCTCTCTTACGCCGTTGCCTGTTATCGGCGTCCCTG
TGCGTGCTTCAGCATTGGATGGACTTGATTCTCTTCTGTCAATTGTGCAGATGCCGAGGGGAGTTCCGGTTGCTACTGTTGCAATCAATAACGCAACCAATGCTGGTTCG
TTGGCAGTAAGGATGTTGGGGGTGGCAGATCCGGATCTACTCTCAAGGATGAGCCAATTTCAAGAAGACACCAAGAAAAATGTATTGAGCAAGGCAGAAAAGTTAGAAAA
AGATGGTTGGGATCTGCAGTGA

mRNA sequence

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Protein sequence

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MGSDSDFPVMRDAAKVLDTFDVPYEIKIVSAHRTPDWMFSYASSAQERGIQIIIAGAGGMVASLTPLPVIGVPVRASALDGLDSLLSIVQMPRGVPVATVAINNATNAGS
LAVRMLGVADPDLLSRMSQFQEDTKKNVLSKAEKLEKDGWDLQ

HG10018593 (gene) of Bottle gourd (Hangzhou Gourd) v1 genome