CuGenDBv2

Gene ID	HG10019484
Organism	Lagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
Description	phosphatidyl-N-methylethanolamine N-methyltransferase
Genome location	Chr04:22311982..22318128
RNA-Seq Expression	HG10019484
Synteny	HG10019484
Gene Ontology terms	GO:0006656 - phosphatidylcholine biosynthetic process (biological process) GO:0032259 - methylation (biological process) GO:0005789 - endoplasmic reticulum membrane (cellular component) GO:0016021 - integral component of membrane (cellular component) GO:0000773 - phosphatidyl-N-methylethanolamine N-methyltransferase activity (molecular function) GO:0004608 - phosphatidylethanolamine N-methyltransferase activity (molecular function) GO:0080101 - phosphatidyl-N-dimethylethanolamine N-methyltransferase activity (molecular function)
InterPro domains	IPR007318 - Phospholipid methyltransferase IPR024960 - Phosphatidyl-N-methylethanolamine/Phosphatidylethanolamine N-methyltransferase

Homology

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GenBank top hits

e value

%identity

Alignment

KAG7036543.1 Phosphatidyl-N-methylethanolamine N-methyltransferase [Cucurbita argyrosperma subsp. argyrosperma]

1.3e-82

90.24

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Query:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        M +LAVIGVLLPFPYYYVLW RPQLWVNLCGK  EP KLMAQVSVFLKLLQFLSI HVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGE+GVYYGVRFGK
Subjt:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS
        NIPWVTEFPFGYIKDPQYVGS+LSL ACLSWVPLQYILLWT+GY+FMM +ESKED  TRAKPQS
Subjt:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS

XP_004137657.1 phosphatidyl-N-methylethanolamine N-methyltransferase [Cucumis sativus]

6.0e-88

95.73

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Query:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MGI AVIGVLLPFPYYYVLWNRPQLWVNLCGKS EPCKLMAQVSVFLKLLQFLSI HVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
Subjt:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS
        NIPWVTEFPFGYIKDPQYVGS+LSLFACLSWVPL+YILLWTLGYIFMMH+ESKED ATRAKPQS
Subjt:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS

XP_008465151.2 PREDICTED: phosphatidyl-N-methylethanolamine N-methyltransferase [Cucumis melo]

1.4e-89

96.95

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Query:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKS EPCKLMAQVSVFLKLLQFLSI HVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
Subjt:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS
        NIPWVTEFPFGYIKDPQYVGS+LSLFACLSWVPL+YILLWTLGYIFMMH+ESKEDPATRAKPQS
Subjt:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS

XP_023523751.1 phosphatidyl-N-methylethanolamine N-methyltransferase [Cucurbita pepo subsp. pepo]

2.9e-82

89.63

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Query:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        M +LAVIGVLLPFPYYYVLW RPQLWVNLCGK  EP KLMAQVSVFLKLLQFLSI HVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGE+GVYYGVRFGK
Subjt:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS
        NIPWVTEFPFGYIKDPQYVGS+LSL ACLSWVPLQYILLWT+GY+FMM +ESKED  TRAKPQ+
Subjt:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS

XP_038903463.1 phosphatidyl-N-methylethanolamine N-methyltransferase [Benincasa hispida]

6.0e-88

94.51

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Query:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MGILAV+GVLLPFPYYYVLW+RPQLWVNLCGKS +PCKLMAQVSVFLKLLQFLSIFHVSSF+WPPPLYFWPLMAFGQFLNFRVYQLLGE+GVYYGVRFGK
Subjt:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS
        NIPWVTEFPFGYIKDPQYVGS+LSLFACLSWVPLQYI+LWTLGYIFMMHIESKE PATRAKPQS
Subjt:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS

TrEMBL top hits

e value

%identity

Alignment

A0A1S3CPQ5 phosphatidyl-N-methylethanolamine N-methyltransferase

6.9e-90

96.95

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Query:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKS EPCKLMAQVSVFLKLLQFLSI HVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
Subjt:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS
        NIPWVTEFPFGYIKDPQYVGS+LSLFACLSWVPL+YILLWTLGYIFMMH+ESKEDPATRAKPQS
Subjt:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS

A0A540MA33 Phosphatidyl-N-methylethanolamine N-methyltransferase

2.8e-75

80.49

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Query:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MGI A IGVL PFP+YY LW+ PQ WV LCGK  +PCK+MA VS FLKL+QFLS+F VS+FSWPPPLYFWPL+AFGQFLNFRVYQLLGESG YYGVRFGK
Subjt:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS
        NIPWVTEFPFGY+KDPQYVGS+LSLFAC+SWVP QYI LWTLGY+ M+++ESKEDPATRAKP S
Subjt:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS

A0A6J1DHC8 phosphatidyl-N-methylethanolamine N-methyltransferase

3.1e-82

88.41

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Query:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MGI+A IGVLLPFP+YYVLW RPQLW N CGK  EPCKLMA+VS+FLKLLQFLSI HVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
Subjt:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS
        NIPWVTEFPFGYI+DPQYVGS+LS+FACLSWVPLQYILL TLGY+FMM +ESKEDP TRAKPQS
Subjt:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS

A0A6J1GCG7 phosphatidyl-N-methylethanolamine N-methyltransferase

3.1e-82

89.63

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Query:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        M +LAVIGVLLPFPYYYVLW RPQLWVNLCGK  EP KLMAQVSVFLKLLQ LSI HVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGE+GVYYGVRFGK
Subjt:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS
        NIPWVTEFPFGYIKDPQYVGS+LSL ACLSWVPLQYILLWT+GY+FMM +ESKED  TRAKPQS
Subjt:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS

A0A6J1KB80 phosphatidyl-N-methylethanolamine N-methyltransferase

1.4e-82

89.63

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Query:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        M +LAVIGVLLPFPYYY+LW RPQLWVNLCGK  EP KLMAQVSVFLKLLQFLSI HVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGE+GVYYGVRFGK
Subjt:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS
        NIPWVTEFPFGYIKDPQYVGS+LSL ACLSWVPLQYILLWT+GY+FMM +ESKED  TRAKPQS
Subjt:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAKPQS

SwissProt top hits

e value

%identity

Alignment

Q9SAH5 Phosphatidyl-N-methylethanolamine N-methyltransferase

3.4e-70

75.16

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Query:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MG+LA IGVLLPFP+Y+ LW   Q WVNLCG+  +P  +MA+VS  LK  Q LS+F V+S SWPPPLYFWPLMAFGQFLNFRVYQLLGE+G YYGVRFGK
Subjt:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAK
        NIPWVTEFPFG I+DPQYVGS++SL ACLSWVP QYILLW+LGY+FMM +ESKEDP  RAK
Subjt:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAK

Arabidopsis top hits

e value

%identity

Alignment

AT1G80860.1 phospholipid N-methyltransferase

2.5e-71

75.16

Show/hide

Query:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MG+LA IGVLLPFP+Y+ LW   Q WVNLCG+  +P  +MA+VS  LK  Q LS+F V+S SWPPPLYFWPLMAFGQFLNFRVYQLLGE+G YYGVRFGK
Subjt:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAK
        NIPWVTEFPFG I+DPQYVGS++SL ACLSWVP QYILLW+LGY+FMM +ESKEDP  RAK
Subjt:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAK

AT1G80860.2 phospholipid N-methyltransferase

2.5e-71

75.16

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Query:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK
        MG+LA IGVLLPFP+Y+ LW   Q WVNLCG+  +P  +MA+VS  LK  Q LS+F V+S SWPPPLYFWPLMAFGQFLNFRVYQLLGE+G YYGVRFGK
Subjt:  MGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLLQFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGK

Query:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAK
        NIPWVTEFPFG I+DPQYVGS++SL ACLSWVP QYILLW+LGY+FMM +ESKEDP  RAK
Subjt:  NIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRAK

Sequences

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CDS sequence

Show/hide CDS sequence

ATGGTGGAGGCCGCAAGGAGGGGAGGAGAGAGAAAGCCCAATAACTTGACCCAACACAGGGCCCAGGGCCCATATCGGTTCCAACGTATACCGGTCGAAAGGGCTACTCT
GCATCTTCGTCTTCCTGTGAATCATTTTCCCGAGAAAGTGGGGAGAAAATCCGGCGACAAAATTATCAGAATGGGCATTTTGGCAGTAATTGGAGTGTTGTTGCCATTTC
CGTACTACTACGTATTATGGAATCGTCCACAGTTGTGGGTAAACTTGTGCGGCAAATCGCTCGAACCCTGCAAATTGATGGCCCAGGTCTCGGTTTTTCTCAAGTTGCTT
CAGTTCCTCTCCATCTTTCATGTCTCCTCCTTCTCATGGCCGCCGCCGCTATACTTCTGGCCTCTCATGGCCTTCGGACAGTTCTTGAACTTCAGGGTCTACCAGTTACT
TGGTGAATCTGGTGTTTACTACGGAGTACGATTTGGGAAGAACATTCCATGGGTAACAGAATTTCCATTTGGATATATAAAAGATCCTCAGTATGTGGGAAGCATGTTGA
GCCTTTTTGCTTGTCTTTCCTGGGTACCCTTACAATATATTCTGCTCTGGACTCTGGGGTACATTTTTATGATGCATATTGAATCCAAGGAAGATCCTGCAACTCGGGCA
AAGCCTCAAAGTTGA

mRNA sequence

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Protein sequence

Show/hide protein sequence

MVEAARRGGERKPNNLTQHRAQGPYRFQRIPVERATLHLRLPVNHFPEKVGRKSGDKIIRMGILAVIGVLLPFPYYYVLWNRPQLWVNLCGKSLEPCKLMAQVSVFLKLL
QFLSIFHVSSFSWPPPLYFWPLMAFGQFLNFRVYQLLGESGVYYGVRFGKNIPWVTEFPFGYIKDPQYVGSMLSLFACLSWVPLQYILLWTLGYIFMMHIESKEDPATRA
KPQS

HG10019484 (gene) of Bottle gourd (Hangzhou Gourd) v1 genome