CuGenDBv2

Gene ID	HG10020714
Organism	Lagenaria siceraria cv. Hangzhou Gourd (Bottle gourd (Hangzhou Gourd) v1)
Description	exonuclease 1
Genome location	Chr05:1765290..1770182
RNA-Seq Expression	HG10020714
Synteny	HG10020714
Gene Ontology terms	GO:0006281 - DNA repair (biological process) GO:0090305 - nucleic acid phosphodiester bond hydrolysis (biological process) GO:0003677 - DNA binding (molecular function) GO:0004527 - exonuclease activity (molecular function) GO:0017108 - 5'-flap endonuclease activity (molecular function) GO:0046872 - metal ion binding (molecular function)
InterPro domains	IPR006084 - XPG/Rad2 endonuclease IPR006085 - XPG, N-terminal IPR006086 - XPG-I domain IPR008918 - Helix-hairpin-helix motif, class 2 IPR029060 - PIN-like domain superfamily IPR036279 - 5'-3' exonuclease, C-terminal domain superfamily IPR044752 - Exonuclease 1-like, PIN-like domain

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

XP_022923945.1 exonuclease 1 [Cucurbita moschata]

1.9e-258

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Query:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
        MGIKDLLRFMKPYIEPIHIKKYAGKRV   A S                  G Y         SMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
Subjt:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV

Query:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
        FDGGNVPCK  TEQ+RHRRRE NRELAMEKLKEGNVGAASELFQ               LLREH IEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
Subjt:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS

Query:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK
        DLIAYGCKATIFKMDRYGNGEEM+LDKIFDSAGCTPSFR FDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEK K+MPEDYFK
Subjt:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK

Query:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP
        LFR+AMAVFQHAQIYDAETRKL+HMKPLPLELLQ LDEEIDFLGP          DMPPSIA SIAEGRLNPITMEAF+Y PSEE RQDL+QIKNNERLP
Subjt:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP

Query:  RTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSK-ELALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEEVSV
        R EAAE    +SCFMVFV KD+ERHIPDKR KP+V  +NSK ELALEKL TPL VQ TNEDK VL YKS+KIPDNNPFKRRK DELH+DL QSVDEEV V
Subjt:  RTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSK-ELALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEEVSV

Query:  IIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNSILN
        I EDECEE SC + DNL LKSS+K K+N+AL DQMDNV+E +SG+TQEEDLVLLE TPESQKSVSS +SSVIGRKRVVGKENKRKS+C SS  PKNSILN
Subjt:  IIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNSILN

Query:  FFSRV
        FF RV
Subjt:  FFSRV

XP_023001042.1 exonuclease 1 [Cucurbita maxima]

7.2e-258

80.1

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Query:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
        MGIKDLLRFMKPYIEPIHIKKYAGKRV   A S                  G Y         SMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
Subjt:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV

Query:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
        FDGGNVPCK  TEQERHRRREANRELAMEKLKEGNVGAASELFQ               LLREH IEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
Subjt:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS

Query:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK
        DLIAYGCKATIFKMDRYGNGEEM+LDKIFDSAGCTPSFR FDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEK KQMPEDYFK
Subjt:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK

Query:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP
        LFR+AMAVFQHAQIYDAETRKL+HMKPLPLELLQ LDEEIDFLGP          DMPPSIA SIAEG LNPITMEAF+Y PSEE RQDL+QIKNNERLP
Subjt:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP

Query:  R---TEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSK-ELALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEE
        R    EAAE   K+SCFMVFV KD+ERHIPDKR KP+V   NSK ELALEKL TPL VQ TNEDK VL YKS+KIPDNNPFKRRK DELH+DL QSVDEE
Subjt:  R---TEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSK-ELALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEE

Query:  VSVIIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNS
          VI EDECEE SC + DNL LKSS+K K+NEAL DQMDNV+E +SG+TQEEDLVLLE TPESQKSVSS +SSVIGRKRVVGKENKRKS+C SS  PKNS
Subjt:  VSVIIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNS

Query:  ILNFFSRV
        ILNFF RV
Subjt:  ILNFFSRV

XP_023519641.1 exonuclease 1 [Cucurbita pepo subsp. pepo]

2.7e-257

79.61

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Query:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
        MGIKDLLRFMKPYIEPIHIKKYAGKRV   A S                  G Y         SMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
Subjt:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV

Query:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
        FDGGNVPCK  TEQERHRRREANRELAMEKLKEGNVGAASELFQ               LLREH IEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
Subjt:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS

Query:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK
        DLIAYGCKATIFKMDRYGNGEEM+LDKIFDSAGCTPSFR FD ELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEK K+MPEDYFK
Subjt:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK

Query:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP
        LFR+AMAVFQHAQIYDAETRKL+HMKPLPLELLQ LDEEIDFLGP          D+PPSIA SIAEGRLNPITMEAF+Y PSEE RQDL+QIKNNERLP
Subjt:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP

Query:  R---TEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSK-ELALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEE
        R    EAAE   K+SCFMVFV KD+ERHIPDKR KP+V   NSK +LALEKL TPL VQ TNEDK VL YKS+KIPDNNPFKRRK DELH+DL QSVDEE
Subjt:  R---TEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSK-ELALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEE

Query:  VSVIIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNS
        V VI ED CEE SC + DNL LKSS+K K+NEAL DQMDNV+E +SG+TQEEDL+LLE TPESQKSVSS +SSVIGRKRVVGKENKRKS+C SSG PKNS
Subjt:  VSVIIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNS

Query:  ILNFFSRV
        ILNFF RV
Subjt:  ILNFFSRV

XP_038893924.1 exonuclease 1 isoform X1 [Benincasa hispida]

2.1e-273

83.28

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Query:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
        MGIKDLLRFMKPYIEPIHIKKYAGKRV   A S                  G Y         SMEICLNS+ DKKWRYLDYCMHRINLLRHYKIVPVVV
Subjt:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV

Query:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
        FDGGN PCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ               LLREH IEFVVAPYEADAQLAYLSSLG QNGGIAAVITEDS
Subjt:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS

Query:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK
        DLIAYGCKA IFKMDRYGNGEEM+LDKIF+SA CTPSFRNFD ELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLER LSVLKLEKKKQMPEDYFK
Subjt:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK

Query:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP
        LFRQAMAVFQHAQIYD E RKLRHMKPL  ELLQ+LDEEIDFLGP          DMPPSIAVSIAEGRLNPITMEAFNYF SEEC QDLIQIKNNERLP
Subjt:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP

Query:  RTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSKELALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEEVSVI
        RTEAAEV GKESCF VFV KDRERHIPDKR KP+VGDKNSKELA+EKLITPL++QRTNEDK VLDYKSIK PDNNPFKRRK DEL LDL QSVD+EVSVI
Subjt:  RTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSKELALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEEVSVI

Query:  IEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNSILNF
         ED+ EELSCETPDNLILKSS+K K +EALSDQMDNVTEHISGITQEEDL+LLE TPESQKSVSSKTSSVIGRKRVVGKENKRK+NC S+GIPKNSILNF
Subjt:  IEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNSILNF

Query:  FSRV
        FSRV
Subjt:  FSRV

XP_038893925.1 exonuclease 1 isoform X2 [Benincasa hispida]

1.2e-263

87.18

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Query:  LAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVVFDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ--------------
        +AAQGSMEICLNS+ DKKWRYLDYCMHRINLLRHYKIVPVVVFDGGN PCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ              
Subjt:  LAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVVFDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ--------------

Query:  -LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDSDLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFL
         LLREH IEFVVAPYEADAQLAYLSSLG QNGGIAAVITEDSDLIAYGCKA IFKMDRYGNGEEM+LDKIF+SA CTPSFRNFD ELLTGMCVLAGCDFL
Subjt:  -LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDSDLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFL

Query:  PSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFKLFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMP
        PSVPGIGIAKAYALVSKYRNLER LSVLKLEKKKQMPEDYFKLFRQAMAVFQHAQIYD E RKLRHMKPL  ELLQ+LDEEIDFLGP          DMP
Subjt:  PSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFKLFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMP

Query:  PSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLPRTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSKELALEKLITPLNVQRTN
        PSIAVSIAEGRLNPITMEAFNYF SEEC QDLIQIKNNERLPRTEAAEV GKESCF VFV KDRERHIPDKR KP+VGDKNSKELA+EKLITPL++QRTN
Subjt:  PSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLPRTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSKELALEKLITPLNVQRTN

Query:  EDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEEVSVIIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPE
        EDK VLDYKSIK PDNNPFKRRK DEL LDL QSVD+EVSVI ED+ EELSCETPDNLILKSS+K K +EALSDQMDNVTEHISGITQEEDL+LLE TPE
Subjt:  EDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEEVSVIIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPE

Query:  SQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNSILNFFSRV
        SQKSVSSKTSSVIGRKRVVGKENKRK+NC S+GIPKNSILNFFSRV
Subjt:  SQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNSILNFFSRV

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LVU6 Uncharacterized protein

1.8e-246

77.69

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Query:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
        MGIKDLLRFMKPYIEPIHIKKYAG+RV   A S                  G Y         SMEICLNS+SDKKWRY+DYCMHRINLLRHY+IVPVVV
Subjt:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV

Query:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
        FDGGN+PCKAVT QERHR++E NRELAMEKLKEGNV AASELFQ               LLREH IEFVVAPYEADAQLAYLSSLGT NGGIAAVITEDS
Subjt:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS

Query:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK
        D+IAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSF++FDKELLTGMCVLAGCDFLPSVPGIGIA+AYALVSKYRNLER LS LKL+KK+QMPEDYFK
Subjt:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK

Query:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP
        LFRQAMAVFQHA+IYDAETRKL  MKPLPLELLQ L EEIDFLGP          DMPPSIAVSIAEGRLNP+TMEAFNYF SEEC QDLI IKN E LP
Subjt:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP

Query:  RTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSKE-LALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEEVSV
        RTE AEV  +ESCFMV V KDRERHIPDK+ KPV G K SKE  ALEKLITP +V RTNE K VL+YKSIK PDNNPFKRRKVDEL L+ TQ VDEEVSV
Subjt:  RTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSKE-LALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEEVSV

Query:  IIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNSILN
        + EDEC  LS  T DNLI KSS K KLNEAL+DQ DN  EHISG+TQEEDLVLLE  PESQKSV+SK SS IGRKRVVGKENK KSN  SSGIPKNSILN
Subjt:  IIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNSILN

Query:  FFSRV
        FFSRV
Subjt:  FFSRV

A0A1S3CHX5 exonuclease 1

4.6e-250

78.02

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Query:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
        MGIKDLLRFMKPYIEPIHIKKYAG+RV   A S                  G Y         SMEICLNS+SDKKWRY+DYCMHRINLLRHYKIVPVVV
Subjt:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV

Query:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
        FDGGN+PCKAVT+QERHR++E NRELAMEKLKEGN+ AASELFQ               LLREH IEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
Subjt:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS

Query:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK
        D+IAYGCKATIFKMDRYGNGEEMMLDKIF+SA CTPSFR+FDKELLTGMCVLAGCDFLPSVPGIGIA+AYALVSK+RNLE  LS LKL+KK++MPEDYFK
Subjt:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK

Query:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP
        LFRQAMAVFQHAQIYDAETRKL  MKPLPLELLQ+LDEEIDFLGP          DMPPSIAVSIAEGRLNP+TMEAF+YF SEEC QDLI IKNNE LP
Subjt:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP

Query:  RTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSK-ELALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEEVSV
        RTE AEV GKESCFMV V KDRERHIPDKR KPV G KNSK E ALEKLITP +V RTNEDK VL YKSIK PDNNPFKRRKVDEL LDL Q VDEEVSV
Subjt:  RTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSK-ELALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEEVSV

Query:  IIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNSILN
        + EDEC  LSC T DNLI KSS K KLNEAL+ Q DN TEHISG+TQEED VLLE  PESQKS+++K SSVIGRKRVVGKENK KS   SSGIPKNSILN
Subjt:  IIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNSILN

Query:  FFSRV
        FFS+V
Subjt:  FFSRV

A0A6J1C8B0 exonuclease 1

2.2e-252

78.35

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Query:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
        MGIKDLLRFMKPYI+PIHIKKYAGKRV   A S                  G Y         SMEICLNSDSD+K RYLDYCMHRINLLRHYKIVPVVV
Subjt:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV

Query:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
        FDGGNVPCKA TEQERHR+REAN+ELAMEKLKEGNVGAASELFQ               LLRE  IEFVVAPYEADAQLAYLSSL TQNGGIAAVITEDS
Subjt:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS

Query:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK
        DLIAYGCKA IFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEK+KQMPEDYFK
Subjt:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK

Query:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP
         FRQAMAVFQHAQIYD ETRKLRHMK LP+ LLQSLD EIDFLGP          DMPPSIA SIAEGRLNPITMEAF+YFPS ECRQD ++IKN  RLP
Subjt:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP

Query:  RTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSK-ELALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEEVSV
        R EAAEV  KESCFMVF  KD ER IPDKR KPVV +KN K ELALEKL TPL+VQRTNEDK V+DYKS+K P+NNPFKRRK D+L LDLT S DEE+ V
Subjt:  RTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSK-ELALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEEVSV

Query:  IIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNSILN
        I EDECEE SC+T DNLIL+SS+K KL + LS Q+DN +E+ S +TQEEDLVLLE TPESQKSVSSK S+VIGRKRVVGKENKRKSNC SSGI KNSILN
Subjt:  IIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNSILN

Query:  FFSRV
        FFSRV
Subjt:  FFSRV

A0A6J1EDD8 exonuclease 1

9.2e-259

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Query:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
        MGIKDLLRFMKPYIEPIHIKKYAGKRV   A S                  G Y         SMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
Subjt:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV

Query:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
        FDGGNVPCK  TEQ+RHRRRE NRELAMEKLKEGNVGAASELFQ               LLREH IEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
Subjt:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS

Query:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK
        DLIAYGCKATIFKMDRYGNGEEM+LDKIFDSAGCTPSFR FDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEK K+MPEDYFK
Subjt:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK

Query:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP
        LFR+AMAVFQHAQIYDAETRKL+HMKPLPLELLQ LDEEIDFLGP          DMPPSIA SIAEGRLNPITMEAF+Y PSEE RQDL+QIKNNERLP
Subjt:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP

Query:  RTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSK-ELALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEEVSV
        R EAAE    +SCFMVFV KD+ERHIPDKR KP+V  +NSK ELALEKL TPL VQ TNEDK VL YKS+KIPDNNPFKRRK DELH+DL QSVDEEV V
Subjt:  RTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSK-ELALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEEVSV

Query:  IIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNSILN
        I EDECEE SC + DNL LKSS+K K+N+AL DQMDNV+E +SG+TQEEDLVLLE TPESQKSVSS +SSVIGRKRVVGKENKRKS+C SS  PKNSILN
Subjt:  IIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNSILN

Query:  FFSRV
        FF RV
Subjt:  FFSRV

A0A6J1KFC4 exonuclease 1

3.5e-258

80.1

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Query:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
        MGIKDLLRFMKPYIEPIHIKKYAGKRV   A S                  G Y         SMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
Subjt:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV

Query:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
        FDGGNVPCK  TEQERHRRREANRELAMEKLKEGNVGAASELFQ               LLREH IEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
Subjt:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQ---------------LLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS

Query:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK
        DLIAYGCKATIFKMDRYGNGEEM+LDKIFDSAGCTPSFR FDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEK KQMPEDYFK
Subjt:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK

Query:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP
        LFR+AMAVFQHAQIYDAETRKL+HMKPLPLELLQ LDEEIDFLGP          DMPPSIA SIAEG LNPITMEAF+Y PSEE RQDL+QIKNNERLP
Subjt:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLP

Query:  R---TEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSK-ELALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEE
        R    EAAE   K+SCFMVFV KD+ERHIPDKR KP+V   NSK ELALEKL TPL VQ TNEDK VL YKS+KIPDNNPFKRRK DELH+DL QSVDEE
Subjt:  R---TEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSK-ELALEKLITPLNVQRTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEE

Query:  VSVIIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNS
          VI EDECEE SC + DNL LKSS+K K+NEAL DQMDNV+E +SG+TQEEDLVLLE TPESQKSVSS +SSVIGRKRVVGKENKRKS+C SS  PKNS
Subjt:  VSVIIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSSKTSSVIGRKRVVGKENKRKSNCISSGIPKNS

Query:  ILNFFSRV
        ILNFF RV
Subjt:  ILNFFSRV

SwissProt top hits

e value

%identity

Alignment

P53695 Exodeoxyribonuclease 1

5.0e-44

32.19

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Query:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
        MGIK LL  +KP  +  H+++++GK +                    + +   ++ +F  A    E+  N ++DK   YL Y +H+  +L++Y + P++V
Subjt:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV

Query:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAAS---------------ELFQLLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
        FDGG +PCKA TEQ+R  RR+   EL  +   EG    A                +L   LREH IE +VAPYEADAQL YL      +G    +ITEDS
Subjt:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAAS---------------ELFQLLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS

Query:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK
        D++ +G +  +FKMD +GN    +  +  D A           E L  M + +GCD+   V G+G+  A   + KY      +  ++L+K  ++P  + K
Subjt:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK

Query:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFN
         F  A   F+H ++Y  + + L H+ P   EL  S+ E+  F+G F              +A+ IAEGR NPIT  AF+
Subjt:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFN

Q54ED2 Exonuclease 1

1.2e-48

36.97

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Query:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQG-SMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVV
        MGI  LL  + P  + IH+K YA KRV                         GY  L   A   S EI L   +     Y++Y + RI +L  YK++PVV
Subjt:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQG-SMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVV

Query:  VFDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQL---------------LREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITED
        +FDGG +P K + EQER R RE  +  A   L EGN   A+  FQ                LR  K+E++VAPYEADAQL YLS      G + A+ITED
Subjt:  VFDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELFQL---------------LREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITED

Query:  SDLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYF
        SDL+A+G    IFKMD+YG  +E+  + +         F +F++ +L  MC+L+GCD+LPS+ G+G+  ++ L+ ++R++E+V   LK E K    ++Y 
Subjt:  SDLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYF

Query:  KLFRQAMAVFQHAQIYDAETRKLRHMKPLP
        + F +A   F+H +++D  +R L  + PLP
Subjt:  KLFRQAMAVFQHAQIYDAETRKLRHMKPLP

Q60GC1 Exonuclease 1

4.8e-55

38.74

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Query:  RYLDYCMHRINLLRHYKIVPVVVFDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGA---------------ASELFQLLREHKIEFVVAPYEADA
        R+++YCMHR+N+LRH+ + P++VFDGG++P K   E +R R R+ N E A E    GN  A               A EL Q+L++ K++++VAPYEADA
Subjt:  RYLDYCMHRINLLRHYKIVPVVVFDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGA---------------ASELFQLLREHKIEFVVAPYEADA

Query:  QLAYLSSLGTQNGGIAAVITEDSDLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTP-SFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKY
        Q+ +LS     N  + AVITEDSDLI +GC   IFKMD++G G E  + ++     C       F  ++L  MC+L+GCD+LPS+PG+G+ +A+AL+ K 
Subjt:  QLAYLSSLGTQNGGIAAVITEDSDLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTP-SFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKY

Query:  RNLERVLSVLKLEKKKQMPEDYFKLFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITME
        +  E+V+  L+      +P  Y + FR+A+  FQ  ++YD  T  + H+  +P        E++DFLGP+          +P ++A  IA+G ++PIT E
Subjt:  RNLERVLSVLKLEKKKQMPEDYFKLFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITME

Query:  AF
         F
Subjt:  AF

Q8L6Z7 Exonuclease 1

7.5e-56

35.45

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Query:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
        MGI+ LL  +K  + PIHIK+  G       V++ ++S L                   A   S E+C    +    R++ YCMHR+NLLRH+ + P++V
Subjt:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV

Query:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGA---------------ASELFQLLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
        FDGG +P K   E +R R R+ N   A+E    GN  A               A EL Q+LR+  +++VVAPYEADAQ+A+L+        + A+ITEDS
Subjt:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGA---------------ASELFQLLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS

Query:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK
        DLI +GC   IFKMD++G+G E    K+  +     S   F  ++L  MC+L+GCD+L S+PG+G+ +A+AL++K+++ +RV+  LK      +P  Y +
Subjt:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK

Query:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAF
         F++A+  F+H ++YD     + H+     ++  +L E+ DF+GP           MP  IA  IA G+L+P T   F
Subjt:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAF

Q9W6K2 Exonuclease 1

1.2e-42

30.93

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Query:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
        MGI+ LL+F+K   EP+H+KKY GK V                    + +   ++  F  A+   ++     +D   +Y+ +CM  +++L  + + P++V
Subjt:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV

Query:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELF---------------QLLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
        FDG  +P K   E+ R  +R+ N +   + L+EG +  A E F               +  R   ++++VAPYEAD+QLAYL+    +N    A+ITEDS
Subjt:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELF---------------QLLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS

Query:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLK----LEKKKQMPE
        DL+A+GCK  + KMD++GNG E+   +      C      F +E    MC+L+GCD+LPS+ GIG+AKA  L+    N +    + K    L+    +PE
Subjt:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLK----LEKKKQMPE

Query:  DYFKLFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLN
         Y + F +A   F +  ++D   RKL  + P   ++     EE+++ GP          +M  S+A+ IA G ++
Subjt:  DYFKLFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLN

Arabidopsis top hits

e value

%identity

Alignment

AT1G18090.1 5'-3' exonuclease family protein

2.9e-124

43.79

Show/hide

Query:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
        MGIKDLLRFMKPYI PIHI+KYAGKRV   A S                  G Y         SME+CL++D  KK RY+DY MHR+NLL+HY+I+PVVV
Subjt:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV

Query:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELF---------------QLLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
         DGGN+PCKA T  ERHR+R+AN + AM KLKEGNV AA+ELF               Q+L+   +EF+VAPYEADAQLAYLSSL  + GGIAAVITEDS
Subjt:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELF---------------QLLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS

Query:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK
        DL+AYGCKA IFKMDRYG GEE++LD +F +    PSF+NFD+EL T MCVLAGCDFLPSVPG+GI++A+A +SKY+++E VLS LK +K K +P+DY  
Subjt:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK

Query:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYF--PSEECRQDLIQIKNNER
         F +A++VFQHA++YD + +KL+H+KPL   LL    E+++FLGP          D+ PS+AV+IAEG ++PITM+AFN+F    +  +  +   K  E+
Subjt:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYF--PSEECRQDLIQIKNNER

Query:  LPRTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSKELALEKLITPLNVQRTNEDKIVLDYKSIK-IPDNNPFKRRKVDELHLDLTQSVDEEV
                +   E    +    D     P+   K  +  K   +  L KL+      + N D++V    +   IPDNNPFK RK DE++L++ +   +E+
Subjt:  LPRTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSKELALEKLITPLNVQRTNEDKIVLDYKSIK-IPDNNPFKRRKVDELHLDLTQSVDEEV

Query:  --SVIIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHIS-----GITQEEDLVLLEQT--------PESQKSVSSKTSSVIGRKRVVGKENK
          S + + +  +++  +P+            +    DQ + VT  +S     GI Q+ +   +++T         E Q  V+  T  V G K    +  K
Subjt:  --SVIIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHIS-----GITQEEDLVLLEQT--------PESQKSVSSKTSSVIGRKRVVGKENK

Query:  RKSNCISSG------IPKNSILNFFSRV
         K++C SS         K+SIL+FF R+
Subjt:  RKSNCISSG------IPKNSILNFFSRV

AT1G18090.2 5'-3' exonuclease family protein

3.8e-124

43.79

Show/hide

Query:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
        MGIKDLLRFMKPYI PIHI+KYAGKRV   A S                  G Y         SME+CL++D  KK RY+DY MHR+NLL+HY+I+PVVV
Subjt:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV

Query:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELF---------------QLLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
         DGGN+PCKA T  ERHR+R+AN + AM KLKEGNV AA+ELF               Q+L+   +EF+VAPYEADAQLAYLSSL  + GGIAAVITEDS
Subjt:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGAASELF---------------QLLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS

Query:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK
        DL+AYGCKA IFKMDRYG GEE++LD +F +    PSF+NFD+EL T MCVLAGCDFLPSVPG+GI++A+A +SKY+++E VLS LK +K K +P+DY  
Subjt:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK

Query:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYF--PSEECRQDLIQIKNNER
         F +A++VFQHA++YD + +KL+H+KPL   LL    E+++FLGP          D+ PS+AV+IAEG ++PITM+AFN+F    +  +  +   K  E+
Subjt:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYF--PSEECRQDLIQIKNNER

Query:  LPRTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSKELALEKLITPLNVQRTNEDKIVLDYKSIK-IPDNNPFKRRKVDELHLDLTQSVDEEV
                +   E    +    D     P+   K  +  K   +  L KL+      + N D++V    +   IPDNNPFK RK DE++L++ +   +E+
Subjt:  LPRTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSKELALEKLITPLNVQRTNEDKIVLDYKSIK-IPDNNPFKRRKVDELHLDLTQSVDEEV

Query:  --SVIIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHIS-----GITQEEDLVLLEQT--------PESQKSVSSKTSSVIGRKRVVGKENK
          S + + +  +++  +P+            +    DQ + VT  +S     GI Q+ +   +++T         E Q  V+  T  V G K    +  K
Subjt:  --SVIIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHIS-----GITQEEDLVLLEQT--------PESQKSVSSKTSSVIGRKRVVGKENK

Query:  RKSNCISSG------IPKNSILNFFSRV
         K++C SS         K+SIL+FF R+
Subjt:  RKSNCISSG------IPKNSILNFFSRV

AT1G29630.1 5'-3' exonuclease family protein

9.7e-27

36.97

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Query:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
        MGI+ LL  +K  + PIHIK+  G       V++ ++S L                   A   S E+C    +    R++ YCMHR+NLLRH+ + P++V
Subjt:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV

Query:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGA---------------ASELFQLLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
        FDGG +P K   E +R R R+ N   A+E    GN  A               A EL Q+LR+  +++VVAPYEADAQ+A+L+        + A+ITEDS
Subjt:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGA---------------ASELFQLLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS

Query:  DLIAYGCKATI
        DLI +GC   I
Subjt:  DLIAYGCKATI

AT1G29630.2 5'-3' exonuclease family protein

5.3e-57

35.45

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Query:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV
        MGI+ LL  +K  + PIHIK+  G       V++ ++S L                   A   S E+C    +    R++ YCMHR+NLLRH+ + P++V
Subjt:  MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVV

Query:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGA---------------ASELFQLLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS
        FDGG +P K   E +R R R+ N   A+E    GN  A               A EL Q+LR+  +++VVAPYEADAQ+A+L+        + A+ITEDS
Subjt:  FDGGNVPCKAVTEQERHRRREANRELAMEKLKEGNVGA---------------ASELFQLLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDS

Query:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK
        DLI +GC   IFKMD++G+G E    K+  +     S   F  ++L  MC+L+GCD+L S+PG+G+ +A+AL++K+++ +RV+  LK      +P  Y +
Subjt:  DLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFK

Query:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAF
         F++A+  F+H ++YD     + H+     ++  +L E+ DF+GP           MP  IA  IA G+L+P T   F
Subjt:  LFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAF

AT1G29630.3 5'-3' exonuclease family protein

7.2e-30

36.36

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Query:  IAAVITEDSDLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKK
        + A+ITEDSDLI +GC   IFKMD++G+G E    K+  +     S   F  ++L  MC+L+GCD+L S+PG+G+ +A+AL++K+++ +RV+  LK    
Subjt:  IAAVITEDSDLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCTPSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKK

Query:  KQMPEDYFKLFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAF
          +P  Y + F++A+  F+H ++YD     + H+     ++  +L E+ DF+GP           MP  IA  IA G+L+P T   F
Subjt:  KQMPEDYFKLFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGPFSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAF

Sequences

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CDS sequence

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ATGGGCATAAAAGACCTCCTCAGATTCATGAAGCCCTACATTGAGCCCATTCACATCAAGAAATACGCGGGCAAACGTGTAAAGTATCGCGCTGTTTCTATTTGTTCGTT
TAGTCCACTTGATTCACTGATCTCTGAATCGAACTTTTTTGCAGGTGGGTATCGACGCCTATTCCTGGCTGCACAAGGGAGTATGGAGATCTGCCTTAATTCTGACAGTG
ATAAGAAATGGCGATATTTAGACTACTGTATGCATAGAATCAATCTGCTTCGTCATTACAAGATAGTCCCGGTTGTTGTTTTTGATGGTGGGAATGTTCCGTGTAAGGCA
GTCACTGAGCAAGAGAGGCACAGAAGAAGAGAGGCGAACAGGGAATTAGCGATGGAGAAGTTGAAGGAAGGGAATGTTGGTGCTGCCTCTGAGCTTTTCCAGCTTCTTAG
AGAACACAAAATCGAATTTGTGGTAGCACCTTATGAGGCTGATGCGCAGTTGGCATATCTTTCGAGCCTCGGAACACAAAACGGAGGAATTGCAGCTGTGATTACAGAGG
ATAGTGACCTGATTGCATATGGTTGTAAAGCTACAATCTTTAAGATGGACCGATATGGCAATGGTGAAGAGATGATGCTAGATAAGATTTTTGACTCCGCAGGCTGCACA
CCTTCCTTCCGAAATTTTGATAAGGAATTGCTCACGGGTATGTGTGTCCTAGCTGGTTGTGATTTTCTTCCTTCTGTTCCTGGAATTGGCATTGCAAAGGCTTATGCTCT
GGTCTCCAAGTATCGGAATTTGGAACGTGTTCTTTCTGTTCTGAAGCTTGAGAAAAAGAAACAAATGCCTGAAGATTACTTCAAACTTTTCAGACAAGCTATGGCAGTCT
TTCAGCATGCACAAATATATGATGCTGAAACGAGGAAGCTTAGACACATGAAACCACTTCCCCTAGAGCTTCTGCAGTCCCTAGATGAAGAAATTGATTTTTTGGGACCT
TTTTCTTTAACCAATTATGGTGGACATAGAGATATGCCTCCTTCAATAGCTGTTTCAATAGCCGAAGGAAGGTTAAACCCCATAACTATGGAGGCCTTTAATTATTTCCC
AAGTGAAGAATGTCGCCAAGACCTTATACAAATAAAGAATAACGAAAGACTTCCAAGGACCGAGGCAGCTGAGGTACCTGGGAAGGAGAGCTGTTTTATGGTCTTCGTCG
ATAAGGACAGAGAAAGACATATCCCGGATAAGAGAAATAAACCGGTTGTAGGTGATAAGAATTCTAAAGAACTGGCACTTGAGAAGCTAATTACACCGTTGAATGTTCAA
AGAACAAATGAAGACAAAATCGTTCTTGACTACAAATCAATAAAGATTCCTGACAACAATCCATTCAAGCGAAGGAAAGTTGATGAATTGCACTTGGATCTCACGCAGAG
TGTTGATGAGGAAGTTTCAGTCATAATTGAGGATGAATGTGAGGAACTATCGTGTGAGACTCCAGATAACTTAATATTAAAATCTTCCAGAAAAATAAAACTAAATGAAG
CTCTCTCTGATCAAATGGATAATGTTACTGAGCATATATCAGGGATAACCCAAGAAGAGGATTTGGTGCTGTTAGAACAGACACCGGAATCCCAAAAGAGTGTAAGCTCA
AAGACAAGCAGTGTCATAGGTAGAAAAAGAGTTGTAGGCAAGGAGAACAAGAGAAAAAGTAACTGTATCAGTTCAGGGATTCCAAAGAATAGTATATTGAACTTTTTCTC
TAGAGTATGA

mRNA sequence

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Protein sequence

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MGIKDLLRFMKPYIEPIHIKKYAGKRVKYRAVSICSFSPLDSLISESNFFAGGYRRLFLAAQGSMEICLNSDSDKKWRYLDYCMHRINLLRHYKIVPVVVFDGGNVPCKA
VTEQERHRRREANRELAMEKLKEGNVGAASELFQLLREHKIEFVVAPYEADAQLAYLSSLGTQNGGIAAVITEDSDLIAYGCKATIFKMDRYGNGEEMMLDKIFDSAGCT
PSFRNFDKELLTGMCVLAGCDFLPSVPGIGIAKAYALVSKYRNLERVLSVLKLEKKKQMPEDYFKLFRQAMAVFQHAQIYDAETRKLRHMKPLPLELLQSLDEEIDFLGP
FSLTNYGGHRDMPPSIAVSIAEGRLNPITMEAFNYFPSEECRQDLIQIKNNERLPRTEAAEVPGKESCFMVFVDKDRERHIPDKRNKPVVGDKNSKELALEKLITPLNVQ
RTNEDKIVLDYKSIKIPDNNPFKRRKVDELHLDLTQSVDEEVSVIIEDECEELSCETPDNLILKSSRKIKLNEALSDQMDNVTEHISGITQEEDLVLLEQTPESQKSVSS
KTSSVIGRKRVVGKENKRKSNCISSGIPKNSILNFFSRV

HG10020714 (gene) of Bottle gourd (Hangzhou Gourd) v1 genome