CuGenDBv2

Gene ID	IVF0017749
Organism	Cucumis melo ssp. agrestis cv. IVF77 (Melon (IVF77) v1)
Description	mediator of RNA polymerase II transcription subunit 18
Genome location	chr03:25782859..25784831
RNA-Seq Expression	IVF0017749
Synteny	IVF0017749
Gene Ontology terms	GO:0006357 - regulation of transcription by RNA polymerase II (biological process) GO:0006369 - termination of RNA polymerase II transcription (biological process) GO:0016592 - mediator complex (cellular component) GO:0070847 - core mediator complex (cellular component) GO:0003712 - transcription coregulator activity (molecular function)
InterPro domains	IPR019095 - Mediator complex, subunit Med18

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

XP_008444669.1 PREDICTED: mediator of RNA polymerase II transcription subunit 18 [Cucumis melo]

2.15e-139

97.24

Show/hide

Query:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR
        MECVVQGIIETQ      ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR
Subjt:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR

Query:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
        LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
Subjt:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT

Query:  AAAAAASLLSDGAGTTM
        AAAAAASLLSDGAGTTM
Subjt:  AAAAAASLLSDGAGTTM

XP_011649597.2 mediator of RNA polymerase II transcription subunit 18 isoform X1 [Cucumis sativus]

1.24e-138

96.77

Show/hide

Query:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR
        MECVVQGIIETQ      ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR
Subjt:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR

Query:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
        LFYALGYKLDHELLRVGFAFRF+RGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
Subjt:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT

Query:  AAAAAASLLSDGAGTTM
        AAAAAASLLSDGAGTTM
Subjt:  AAAAAASLLSDGAGTTM

XP_022144379.1 mediator of RNA polymerase II transcription subunit 18 [Momordica charantia]

2.41e-136

94.93

Show/hide

Query:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR
        MECVVQGIIETQ      ILLQGICGVPRERLRLHEICLKSGP+LGAVASEVRILCDLEQAEP WTVKHIGGA+RGAGAEQLSVLVRTMVESKVSKNVLR
Subjt:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR

Query:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
        LFYALGYKLDHELLRVGFAFRF+RGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
Subjt:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT

Query:  AAAAAASLLSDGAGTTM
        AAAAAASLLSDGAGTTM
Subjt:  AAAAAASLLSDGAGTTM

XP_022951149.1 mediator of RNA polymerase II transcription subunit 18 [Cucurbita moschata]

4.65e-134

92.63

Show/hide

Query:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR
        MECVVQGIIETQ      ILLQGICGVPRERLRLHEICLKSGP+LGAVASEVRI+CDLEQ EP+WTVKHIGGA+RG+GAEQLSVLVRTMVESKVSKNVLR
Subjt:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR

Query:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
        LFYALGYKLDHELLRVGF+FRF+RG HITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
Subjt:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT

Query:  AAAAAASLLSDGAGTTM
        AAAAAASLLSDGAGTTM
Subjt:  AAAAAASLLSDGAGTTM

XP_038885244.1 mediator of RNA polymerase II transcription subunit 18 [Benincasa hispida]

1.77e-138

96.31

Show/hide

Query:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR
        MECVVQGIIETQ      ILLQGICGVPRERLRLHEICLKSGPSLGAVASE+RILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR
Subjt:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR

Query:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
        LFYALGYKLDHELLRVGFAFRF+RGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
Subjt:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT

Query:  AAAAAASLLSDGAGTTM
        AAAAAASLLSDGAGTTM
Subjt:  AAAAAASLLSDGAGTTM

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LNJ4 Uncharacterized protein

2.9e-106

96.33

Show/hide

Query:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR
        MECVVQGIIETQ      ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR
Subjt:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR

Query:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
        LFYALGYKLDHELLRVGFAFRF+RGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
Subjt:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT

Query:  AAAAAASLLS-DGAGTTM
        AAAAAASLLS DGAGTTM
Subjt:  AAAAAASLLS-DGAGTTM

A0A1S3BBM1 mediator of RNA polymerase II transcription subunit 18

3.1e-108

97.24

Show/hide

Query:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR
        MECVVQGIIETQ      ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR
Subjt:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR

Query:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
        LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
Subjt:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT

Query:  AAAAAASLLSDGAGTTM
        AAAAAASLLSDGAGTTM
Subjt:  AAAAAASLLSDGAGTTM

A0A6J1CS50 mediator of RNA polymerase II transcription subunit 18

6.5e-106

94.93

Show/hide

Query:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR
        MECVVQGIIETQ      ILLQGICGVPRERLRLHEICLKSGP+LGAVASEVRILCDLEQAEP WTVKHIGGA+RGAGAEQLSVLVRTMVESKVSKNVLR
Subjt:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR

Query:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
        LFYALGYKLDHELLRVGFAFRF+RGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
Subjt:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT

Query:  AAAAAASLLSDGAGTTM
        AAAAAASLLSDGAGTTM
Subjt:  AAAAAASLLSDGAGTTM

A0A6J1GHW3 mediator of RNA polymerase II transcription subunit 18

3.6e-104

92.63

Show/hide

Query:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR
        MECVVQGIIETQ      ILLQGICGVPRERLRLHEICLKSGP+LGAVASEVRI+CDLEQ EP+WTVKHIGGA+RG+GAEQLSVLVRTMVESKVSKNVLR
Subjt:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR

Query:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
        LFYALGYKLDHELLRVGF+FRF+RG HITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
Subjt:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT

Query:  AAAAAASLLSDGAGTTM
        AAAAAASLLSDGAGTTM
Subjt:  AAAAAASLLSDGAGTTM

A0A6J1KK74 mediator of RNA polymerase II transcription subunit 18

1.8e-103

92.17

Show/hide

Query:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR
        MECVVQGIIETQ      ILLQGICGVPRERLRLHEICLKSGP+LGAVASEVRI+CDLEQ EP+WTVKHIGGA+RG+GAEQLSVLVRTMVESKVSKNVLR
Subjt:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR

Query:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
        LFYALGYKLDHELLRVGF+FRF+RG HITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATS+NYSEVA AVSTFCEYLAPLLHLSKPGISTGVVPT
Subjt:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT

Query:  AAAAAASLLSDGAGTTM
        AAAAAASLLSDGAGTTM
Subjt:  AAAAAASLLSDGAGTTM

SwissProt top hits

e value

%identity

Alignment

Q9SJZ6 Mediator of RNA polymerase II transcription subunit 18

6.1e-93

78.34

Show/hide

Query:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR
        MECVVQGIIETQ      ILLQG+CGV RERLR+HE+CL+SGP+LG V+SEVR+LCDL+Q EPTWTVKH+GGA+RGAGA+Q+SVLVR M+ESKVSKN LR
Subjt:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR

Query:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
        +FYALGYKLDHELL+VGFAF F R AHI+V+VSSVNKM K+H+ DEAVPVTPG+Q+V+VTAPATS+NYSEVA AVS+FCE+LAPL+HLSKP ISTGVVPT
Subjt:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT

Query:  AAAAAASLLSDGAGTTM
        AAAAAASL+SDG GTT+
Subjt:  AAAAAASLLSDGAGTTM

Arabidopsis top hits

e value

%identity

Alignment

AT2G22370.1 unknown protein

4.3e-94

78.34

Show/hide

Query:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR
        MECVVQGIIETQ      ILLQG+CGV RERLR+HE+CL+SGP+LG V+SEVR+LCDL+Q EPTWTVKH+GGA+RGAGA+Q+SVLVR M+ESKVSKN LR
Subjt:  MECVVQGIIETQ------ILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLR

Query:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT
        +FYALGYKLDHELL+VGFAF F R AHI+V+VSSVNKM K+H+ DEAVPVTPG+Q+V+VTAPATS+NYSEVA AVS+FCE+LAPL+HLSKP ISTGVVPT
Subjt:  LFYALGYKLDHELLRVGFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPT

Query:  AAAAAASLLSDGAGTTM
        AAAAAASL+SDG GTT+
Subjt:  AAAAAASLLSDGAGTTM

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGGAGTGTGTGGTTCAGGGCATAATTGAGACCCAGATTCTTCTTCAAGGTATTTGCGGCGTTCCTAGAGAAAGATTGAGGCTCCATGAAATATGCCTAAAAAGTGGACC
TAGCCTAGGTGCTGTAGCATCTGAGGTTCGGATCTTATGCGACCTTGAGCAGGCTGAACCGACATGGACGGTTAAACATATTGGAGGGGCAATTAGAGGTGCAGGTGCTG
AACAACTCTCTGTTCTGGTTAGGACAATGGTAGAAAGCAAAGTTAGCAAGAATGTGCTTCGTCTATTCTATGCACTTGGCTATAAGTTAGATCATGAGCTGCTGAGAGTT
GGTTTTGCCTTCCGCTTCTATCGGGGTGCCCACATAACAGTGACAGTTTCATCAGTTAATAAGATGTTAAAGCTACATTCAACTGATGAGGCTGTACCTGTAACACCTGG
TATACAGCTGGTCGAAGTGACAGCCCCAGCAACTTCTGATAACTATTCTGAAGTAGCCGGTGCAGTGTCGACTTTCTGTGAATATCTTGCACCGCTGCTGCATTTGTCGA
AACCAGGAATATCCACAGGTGTTGTTCCTACTGCTGCGGCCGCGGCAGCCTCGCTTCTATCTGATGGTGCCGGAACAACAATGTAG

mRNA sequence

Show/hide mRNA sequence

Protein sequence

Show/hide protein sequence

MECVVQGIIETQILLQGICGVPRERLRLHEICLKSGPSLGAVASEVRILCDLEQAEPTWTVKHIGGAIRGAGAEQLSVLVRTMVESKVSKNVLRLFYALGYKLDHELLRV
GFAFRFYRGAHITVTVSSVNKMLKLHSTDEAVPVTPGIQLVEVTAPATSDNYSEVAGAVSTFCEYLAPLLHLSKPGISTGVVPTAAAAAASLLSDGAGTTM

IVF0017749 (gene) of Melon (IVF77) v1 genome