CuGenDBv2

Gene ID	IVF0025580
Organism	Cucumis melo ssp. agrestis cv. IVF77 (Melon (IVF77) v1)
Description	DNA topoisomerase 2
Genome location	chr04:23003012..23010097
RNA-Seq Expression	IVF0025580
Synteny	IVF0025580
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0043231 - intracellular membrane-bounded organelle (cellular component) GO:0003677 - DNA binding (molecular function) GO:0046872 - metal ion binding (molecular function) GO:0005524 - ATP binding (molecular function) GO:0003918 - DNA topoisomerase type II (ATP-hydrolyzing) activity (molecular function)
InterPro domains	IPR013506 - DNA topoisomerase, type IIA, subunit B, domain 2 IPR036890 - Histidine kinase/HSP90-like ATPase superfamily IPR034157 - DNA topoisomerase 2, TOPRIM domain IPR031660 - C-terminal associated domain of TOPRIM IPR020568 - Ribosomal protein S5 domain 2-type fold IPR018522 - DNA topoisomerase, type IIA, conserved site IPR014721 - Ribosomal protein S5 domain 2-type fold, subgroup IPR013760 - DNA topoisomerase, type IIA-like domain superfamily IPR013759 - DNA topoisomerase, type IIA, subunit B, C-terminal IPR013758 - DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta IPR013757 - Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily IPR006171 - TOPRIM domain IPR003594 - Histidine kinase/HSP90-like ATPase IPR002205 - DNA topoisomerase, type IIA, subunit A/C-terminal IPR001241 - DNA topoisomerase, type IIA IPR001154 - DNA topoisomerase II, eukaryotic-type

Homology

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GenBank top hits

e value

%identity

Alignment

KAA0048368.1 DNA topoisomerase 2 [Cucumis melo var. makuwa]

0.0

100

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Query:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFD
        GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFD
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFD

Query:  ANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETD
        ANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETD
Subjt:  ANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETD

Query:  EAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPKIS
        EAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPKIS
Subjt:  EAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPKIS

Query:  RNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQE
        RNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQE
Subjt:  RNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQE

Query:  VQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLITQMLEPAENSGISPEKKVRK
        VQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLITQMLEPAENSGISPEKKVRK
Subjt:  VQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLITQMLEPAENSGISPEKKVRK

Query:  IRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEASLDED
        IRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEASLDED
Subjt:  IRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEASLDED

KAG7018075.1 DNA topoisomerase 2 [Cucurbita argyrosperma subsp. argyrosperma]

0.0

90.43

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Query:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSN ANVDS+PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVF+DNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA++FQ EPPKRYHI+PNERWEIVV
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVK+YLWVFINALIDNP+FDSQTKETLT R +SFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD++DGEAIELAFSKKKIE+RKNWLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRNVRRML+GE MLPMDPWYRGFSGTIEKTATKEGGT+YT+S
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDK--EKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRI ELPVRRWT+DYKDFLDSVTRV++K+DK  EKAAKDPFIEQADHHSDDK VSIDVHLTEENM+LA+QEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDK--EKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEF+EKRKR LL+NLE ELLKLENKVRFILAVVN EI VSNR++VDLFHELQ KGFTPFPKKTKSVEPE+AGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPK
        TDEAEESPEVVKGER+SDYEYLLAL IGTLTIEKVQELCN+RDK KGEV++LRKATPKSLWL DLD LEKELDE+DRNDAQ  E+RKQQR K NND+KPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPK

Query:  ISRNAPKAPRNSKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETE
        ISRNAPKAPRNSKKTSN ET+TESMD TT SSTTTEVANNPVVKPKGKAAPRKAPAKK+GKAAV D+DDDDEVLELKDRLAAYK+ESSPEPSEVSAMETE
Subjt:  ISRNAPKAPRNSKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETE

Query:  VQEVQAA-KKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKA--------PAAGGKLGQKLITQMLEPAE
        V +VQAA KKKEPSKRA AKKKTTAKSAQIS  DD DD DFEIKE+ P AAKKGGGR     AAAN KTTK         P A  +LGQKLITQMLEP E
Subjt:  VQEVQAA-KKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKA--------PAAGGKLGQKLITQMLEPAE

Query:  NSGISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIE--DEGKVMGSASSETS-EEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEA
        NSGISPEKKVRKIR SPFNKKSGS+LGR I EEEE+  E  +EGK+MGSASSET+ EEVA    A GRS+R NRTQVRYV+SDSD E V +DSDFDE EA
Subjt:  NSGISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIE--DEGKVMGSASSETS-EEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEA

Query:  SLDED
        +LDED
Subjt:  SLDED

XP_008461811.1 PREDICTED: DNA topoisomerase 2 [Cucumis melo]

0.0

100

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Query:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFD
        GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFD
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFD

Query:  ANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETD
        ANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETD
Subjt:  ANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETD

Query:  EAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPKIS
        EAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPKIS
Subjt:  EAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPKIS

Query:  RNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQE
        RNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQE
Subjt:  RNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQE

Query:  VQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLITQMLEPAENSGISPEKKVRK
        VQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLITQMLEPAENSGISPEKKVRK
Subjt:  VQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLITQMLEPAENSGISPEKKVRK

Query:  IRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEASLDED
        IRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEASLDED
Subjt:  IRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEASLDED

XP_011651769.2 DNA topoisomerase 2 [Cucumis sativus]

0.0

96.07

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Query:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MVVEKKRPLQNSN ANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEN+KMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFS+EFVIETADGRRLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV
        PIITKCK GDNWTRVTFKPDL KFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPV+SFQDYVDLYLKSASS QAEPPKRYHI+PNERWEIVV
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIAN+VMTAVNKKNKNANVKAHNVK+YLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNA+ALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYE+WKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS
        RFLFP+DDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRML+GETMLPMDPWYRGFSGTIEKTATKEGGTTYT+S
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDK--EKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDK  EKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDK--EKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPK
        TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELC+DRDKLKGEVDDLRKATPKSLWLNDLD LEKELDE+DRNDAQTMELRKQQR+KAN DLKPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPK

Query:  ISRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDE---VLELKDRLAAYKIESSPEPSEVSAME
        +SRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAV D+D+DDE   VLELKDRLAAYKIESSPEPSEVSAME
Subjt:  ISRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDE---VLELKDRLAAYKIESSPEPSEVSAME

Query:  TEVQEVQ--AAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGG--RKAAAANGKTTKAPAAGGKLGQKLITQMLEPA-ENS
        TEVQEVQ  AAKKKEPSKRAPAKKKTTAKSAQISISDD++D DFEIKEVDP AAKKGGGRGG  RKAAA N KTTK PAAG KLGQKLITQMLEPA ENS
Subjt:  TEVQEVQ--AAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGG--RKAAAANGKTTKAPAAGGKLGQKLITQMLEPA-ENS

Query:  GISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRT-QVRYVLSDSDDEAVSQDSDFDEDEASLDE
        GISPEKKVRKIRASPFNKKSGSLLGR I EEEED  +DEGK+MGSAS ETSEEV   Q A GRSRRANRT QVRYVLSDSD E  SQDSDFDEDEASLDE
Subjt:  GISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRT-QVRYVLSDSDDEAVSQDSDFDEDEASLDE

Query:  D
        D
Subjt:  D

XP_038905935.1 DNA topoisomerase 2 [Benincasa hispida]

0.0

92.52

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Query:  MVVEKKRPLQNSNTANVDSNPA-GPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSM
        M VEKKRPLQNSN ANVDS+PA GPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRS+SYVPGLYKIFDEILVNAADNKQRDPSM
Subjt:  MVVEKKRPLQNSNTANVDSNPA-GPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSM

Query:  DSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKS
        DSVKV+IDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADG+R+KKYKQVFNDNMGKKS
Subjt:  DSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKS

Query:  EPIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIV
        EPIITKCK GDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVP+KSFQDYVDLYLKSAS+FQ EPPKRYHIKPN+RWEIV
Subjt:  EPIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKN
        VTLSEGQFQQVSFVNGI+TIKGGTHV+YITNQI+NYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKR+NSFGS CELTPEFLKN
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKN

Query:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREA+SKQI
Subjt:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESL
        TENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESL
Subjt:  TENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESL

Query:  RGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQR
        RGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQT KLIKYSDFVNKELILFSMADLQR
Subjt:  RGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQR

Query:  SIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNV
        SIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRN GGKDHASSRYIYTKLSNV
Subjt:  SIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNV

Query:  TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTI
        TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDII+NVRRMLDG TMLPMDPWYRGFSGTIEKTATKEGGT+YT+
Subjt:  TRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTI

Query:  SGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDK--EKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMH
        SGIIEEVSDT LRIVELPVRRWT+DYKDFLDSVT+VA+KHDK  EKAAK+PFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMH
Subjt:  SGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDK--EKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMH

Query:  LFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASN
        LFDANGVIKKYDTPEQILEEFFPLRL+FYEKRKR LL+NLEMELLKLENKVRFIL VVNEEI V NR+KVDLFHELQAKGFTPFPKK KSVEPE+AGAS+
Subjt:  LFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASN

Query:  ETDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKP
        E DEAEESPEVVK  R+SDYEYLL+L IGTLTIEKVQELCN+RDKLKGEVDDLRKATPK+LWLNDLDSLEKELDE+D NDAQ ME RK+QRDK NNDLKP
Subjt:  ETDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKP

Query:  KISRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETE
        KISRNAPKAPRN KKTSN E VTESMDTT+SSTT EVANNPVVKPKGKAAPRKAPAKK GKAAV D DDDDEVLELKDRLAAYKIESSPEPSEVS METE
Subjt:  KISRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETE

Query:  VQEVQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDD---FEIKEVDPQAAKKGGGRGG-RKAAAANGKTTKAPAAGGKLGQKLITQMLEPAENSGIS
        V +VQAAKKKEP+KRA AKKKTTAKSAQ+S+SDD+DDDD   FE+KEV P A KKGGGRGG RKAAA N KTTK PAA  KLGQKLIT+MLEPAENSGIS
Subjt:  VQEVQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDD---FEIKEVDPQAAKKGGGRGG-RKAAAANGKTTKAPAAGGKLGQKLITQMLEPAENSGIS

Query:  PEKKVRKIRASPFNKKSGSLLGRAI-------EEEEEDGIEDEGKVMGSASSETS-EEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDED
        PEKKVRKIRASPFNKKSGS+LGR I       EEEEE GIE+  KVMGSASSET+ EEVAG  PA GRS RANRTQVRYV+SD D E VS+DSD DED
Subjt:  PEKKVRKIRASPFNKKSGSLLGRAI-------EEEEEDGIEDEGKVMGSASSETS-EEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDED

TrEMBL top hits

e value

%identity

Alignment

A0A0A0LEU2 DNA topoisomerase 2

0.0e+00

94.77

Show/hide

Query:  MYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQNCISVFNNGDGVPVEIHQEE
        MYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEN+KMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQNCISVFNNGDGVPVEIHQEE
Subjt:  MYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQNCISVFNNGDGVPVEIHQEE

Query:  KVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPIITKCKEGDNWTRVTFKPDLAKFNMTHLE
        KVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFS+EFVIETADGRRLKKYKQVFNDNMGKKSEPIITKCK GDNWTRVTFKPDL KFNMTHLE
Subjt:  KVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPIITKCKEGDNWTRVTFKPDLAKFNMTHLE

Query:  DDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVEYITN
        DDVVALMKKRVLDLAGCLGKTVKVELNGQRVPV+SFQDYVDLYLKSASS QAEPPKRYHI+PNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVEYITN
Subjt:  DDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVEYITN

Query:  QIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKT
        QIAN+VMTAVNKKNKNANVKAHNVK+YLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTP+FLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKT
Subjt:  QIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKT

Query:  EKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGH
        EKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNA+ALRYGH
Subjt:  EKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGH

Query:  LMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLT
        LMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYE+WKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLT
Subjt:  LMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLT

Query:  KHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKV
        KHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFE         KL    + +  ELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKV
Subjt:  KHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKV

Query:  SQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPI
        SQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFP+DDDKLLNYLNEDGQSIEPTWYMPI
Subjt:  SQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPI

Query:  IPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTISGIIEEVSDTTLRIVELPVRRWTSDYKDFLD
        IPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRML+GETMLPMDPWYRGFSGTIEKTATKEGGTTYT+SGIIEEVSDTTLRIVELPVRRWTSDYKDFLD
Subjt:  IPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTISGIIEEVSDTTLRIVELPVRRWTSDYKDFLD

Query:  SVTRVASKH--DKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEK
        SVTRVASKH  DKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEK
Subjt:  SVTRVASKH--DKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEK

Query:  RKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETDEAEESPEVVKGERISDYEYLLALPIGTL
        RKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETDEAEESPEVVKGERISDYEYLLALPIGTL
Subjt:  RKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETDEAEESPEVVKGERISDYEYLLALPIGTL

Query:  TIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPKISRNAPKAPRNSKKTSNVETVTESMDTTYS
        TIEKVQELC+DRDKLKGEVDDLRKATPKSLWLNDLD LEKELDE+DRNDAQTMELRKQQR+KAN DLKPK+SRNAPKAPRNSKKTSNVETVTESMDTTYS
Subjt:  TIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPKISRNAPKAPRNSKKTSNVETVTESMDTTYS

Query:  STTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPD---EDDDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQEV--QAAKKKEPSKRAPAKKKTTAKS
        STTTEVANNPVVKPKGKAAPRKAPAKKKGKAAV D   +D+DDEVLELKDRLAAYKIESSPEPSEVSAMETEVQEV  QAAKKKEPSKRAPAKKKTTAKS
Subjt:  STTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPD---EDDDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQEV--QAAKKKEPSKRAPAKKKTTAKS

Query:  AQISISDDEDDDDFEIKEVDPQAAKKGGGR---GGRKAAAANGKTTKAPAAGGKLGQKLITQMLEP-AENSGISPEKKVRKIRASPFNKKSGSLLGRAIE
        AQISISDD++D DFEIKEVDP AAKKGGGR   GGRKAAA N KTTK PAAG KLGQKLITQMLEP AENSGISPEKKVRKIRASPFNKKSGSLLGR I 
Subjt:  AQISISDDEDDDDFEIKEVDPQAAKKGGGR---GGRKAAAANGKTTKAPAAGGKLGQKLITQMLEP-AENSGISPEKKVRKIRASPFNKKSGSLLGRAIE

Query:  EEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANR-TQVRYVLSDSDDEAVSQDSDFDEDEASLDED
        EEEED  +DEGK+MGSAS ETSEEV   Q A GRSRRANR TQVRYVLSDSD E  SQDSDFDEDEASLDED
Subjt:  EEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANR-TQVRYVLSDSDDEAVSQDSDFDEDEASLDED

A0A1S3CFK5 DNA topoisomerase 2

0.0e+00

100

Show/hide

Query:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFD
        GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFD
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFD

Query:  ANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETD
        ANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETD
Subjt:  ANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETD

Query:  EAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPKIS
        EAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPKIS
Subjt:  EAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPKIS

Query:  RNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQE
        RNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQE
Subjt:  RNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQE

Query:  VQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLITQMLEPAENSGISPEKKVRK
        VQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLITQMLEPAENSGISPEKKVRK
Subjt:  VQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLITQMLEPAENSGISPEKKVRK

Query:  IRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEASLDED
        IRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEASLDED
Subjt:  IRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEASLDED

A0A5A7TZH5 DNA topoisomerase 2

0.0e+00

100

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Query:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
Subjt:  ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFD
        GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFD
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFD

Query:  ANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETD
        ANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETD
Subjt:  ANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETD

Query:  EAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPKIS
        EAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPKIS
Subjt:  EAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPKIS

Query:  RNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQE
        RNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQE
Subjt:  RNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQE

Query:  VQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLITQMLEPAENSGISPEKKVRK
        VQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLITQMLEPAENSGISPEKKVRK
Subjt:  VQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLITQMLEPAENSGISPEKKVRK

Query:  IRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEASLDED
        IRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEASLDED
Subjt:  IRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEASLDED

A0A6J1F3D6 DNA topoisomerase 2

0.0e+00

90.55

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Query:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSN ANVDS+PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVF+DNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA++FQ EPPKRYHI+PNERWEIVV
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVK+YLWVFINALIDNP+FDSQTKETLT R +SFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD++DGEAIELAFSKKKIE+RKNWLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRNVRRML+GE MLPMDPWYRGFSGTIEKTATKEGGT+YT+S
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKH--DKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRI ELPVRRWT+DYKDFLDSVTRV++K+  DKEKAAKDPFIEQADHHSDDK VSIDVHLTEENM+LA+QEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKH--DKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEF+EKRKR LL+NLE ELLKLENKVRFILAVVN EI VSNR++VDLFHELQ KGFTPFPKKTKSVEPE+AGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPK
        TDEAEESPEVVKGER+SDYEYLLAL IGTLTIEKVQELCN+RDK KGEV++LRKATPKSLWL DLD LEKELDE+DRNDAQ  E+RKQQR K NND+KPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPK

Query:  ISRNAPKAPRNSKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETE
        ISRNAPKAPRNSKKTSN ET+TESMD TT SSTTTEVANNPVVKPKGKAAPRKAPA KKGK AV D+DDDDEVLELKDRLAAYK+ESSPEPSEVSAMETE
Subjt:  ISRNAPKAPRNSKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETE

Query:  VQEVQ-AAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKA-----PAAGGKLGQKLITQMLEPAENSG
        V +VQ AAKKKEPSKRA AKKKTTAKSAQ  ISDD DD DFEIKE+ P AAKKGGGR     AAAN KTTK      P A  +LGQKLITQMLEP ENSG
Subjt:  VQEVQ-AAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKA-----PAAGGKLGQKLITQMLEPAENSG

Query:  ISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIE--DEGKVMGSASSETS-EEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEASLD
        ISPEKKVRKIR SPFNKKSGS+LGR I EEEE+  E  +EGK+MGSASSET+ EEVA    A GRS+R NRTQVRYV+SDSD E V +DSDFDE EA+LD
Subjt:  ISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIE--DEGKVMGSASSETS-EEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEASLD

Query:  ED
        ED
Subjt:  ED

A0A6J1F9E0 DNA topoisomerase 2

0.0e+00

90.55

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Query:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        M VEKKRPLQNSN ANVDS+PAGPKKTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRS++YVPGLYKIFDEILVNAADNKQRDPSMD
Subjt:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        S+KV ID EQN ISVFNNGDGVPVE+HQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVF+DNMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV
        PIITKCKEGDNWT+VTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVD YLKSA++FQ EPPKRYHI+PNERWEIVV
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVV

Query:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV
        TLSEGQFQQVSFVNGIATIKGGTHV+YITNQIANYVMT VNKKNKNANVKAHNVK+YLWVFINALIDNP+FDSQTKETLT R +SFGSACELTP+FLKNV
Subjt:  TLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNV

Query:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
        ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT
Subjt:  ATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQIT

Query:  ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR
        ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATH+NGTVLSFYTMPEYE+WK++LR
Subjt:  ENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLR

Query:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS
        GNASGWSIKYYKGLGTSTSKEGREYFEQL KHKKDFIWQD++DGEAIELAFSKKKIE+RKNWLRQFE GTHLDQ+ KLIKYSDFVNKELILFSMADLQRS
Subjt:  GNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRS

Query:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT
        IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN T
Subjt:  IPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVT

Query:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS
        RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSY+PNYNPRDIIRNVRRML+GE MLPMDPWYRGFSGTIEKTATKEGGT+YT+S
Subjt:  RFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTIS

Query:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKH--DKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        GIIEEVSDTTLRI ELPVRRWT+DYKDFLDSVTRV++K+  DKEKAAKDPFIEQADHHSDDK VSIDVHLTEENM+LA+QEGLKKKFKLTTTVSTSNMHL
Subjt:  GIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKH--DKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE
        FDANGVIKKYDTPEQILEEFFPLRLEF+EKRKR LL+NLE ELLKLENKVRFILAVVN EI VSNR++VDLFHELQ KGFTPFPKKTKSVEPE+AGASNE
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNE

Query:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPK
        TDEAEESPEVVKGER+SDYEYLLAL IGTLTIEKVQELCN+RDK KGEV++LRKATPKSLWL DLD LEKELDE+DRNDAQ  E+RKQQR K NND+KPK
Subjt:  TDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPK

Query:  ISRNAPKAPRNSKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETE
        ISRNAPKAPRNSKKTSN ET+TESMD TT SSTTTEVANNPVVKPKGKAAPRKAPAKK+GK AV D+DDDDEVLELKDRLAAYK+ESSPEPSEVSAMETE
Subjt:  ISRNAPKAPRNSKKTSNVETVTESMD-TTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETE

Query:  VQEVQ-AAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKA-----PAAGGKLGQKLITQMLEPAENSG
        V +VQ AAKKKEPSKRA AKKKTTAKSAQ  ISDD DD DFEIKE+ P AAKKGGGR     AAAN KTTK      P A  +LGQKLITQMLEP ENSG
Subjt:  VQEVQ-AAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKA-----PAAGGKLGQKLITQMLEPAENSG

Query:  ISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIE--DEGKVMGSASSETS-EEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEASLD
        ISPEKKVRKIR SPFNKKSGS+LGR I EEEE+  E  +EGK+MGSASSET+ EEVA    A GRS+R NRTQVRYV+SDSD E V +DSDFDE EA+LD
Subjt:  ISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIE--DEGKVMGSASSETS-EEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEASLD

Query:  ED
        ED
Subjt:  ED

SwissProt top hits

e value

%identity

Alignment

O24308 DNA topoisomerase 2

0.0e+00

63.05

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Query:  KKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKV
        +KRPLQ SN AN+      P KTIEEMYQKK+QLEHILLRPDTYVGSIEKHTQNLWVYEND+MVHR++SYVPGLYKIFDEILVNAADNKQRDPSMDS+KV
Subjt:  KKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKV

Query:  NIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPIIT
         ID E N +SV+NNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADGRRLKKYKQVF++NMG K EP+IT
Subjt:  NIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPIIT

Query:  KCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVVTLSE
        KCK  +NWT+VTFKPDL KF M +LE+DVVALMKKRVLD+AGC GKTVKVELNG  +  KSF+DY DL+LK A   +  P  R H K  +RWEI ++LS+
Subjt:  KCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVVTLSE

Query:  GQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNVATKS
        GQFQQVSFVN IATIKGGTHV+YITNQI  Y+M  VNKK K+ANVKAH VKN+LWVF+N+LIDNP+FDSQTKETLT R  SFGS C++    LK+V  KS
Subjt:  GQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNVATKS

Query:  GIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKE
        GI+D++LSW +FKQSKDLKKTDG KT+++ G  K EDAN AGG+NSEKCTLILTEGDSAKALAMAGL VVGRD YGVFPLRGKLLNVREASSKQI +N+E
Subjt:  GIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKE

Query:  IQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNAS
        IQ IK+ILGLQQ KEY N K+LRYGHLMIM DQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEF TP+++A+H N T+ SFY+MPEYE+WKE L  +A+
Subjt:  IQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNAS

Query:  GWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSM
         W IKYYKGLGTST +EGREYF  L +H+KDFIW D+ DG AIELAFSKKK E RK W+R FEPGT  D   KLI Y DFVNKELILFS AD        
Subjt:  GWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSM

Query:  VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLF
                   LF SFK+   KE KV+QF GYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL PNGQFGT N GGKDHAS+RYIYT+LS VTR LF
Subjt:  VDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLF

Query:  PKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTISGIIE
         + DDKLL YLNEDG+SIEP WYMPIIP VLVNGSEGIGTGWSSY+PNYNPR+II NVRR+L+GE ++PMDPWY+GF GTIEK+A KEGG  Y ++G + 
Subjt:  PKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYTISGIIE

Query:  EVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGV
        E+ + T RI ELP+R+WT DYK FL+S+T      D     KDP IE    + DD IV I++ +  E +   +QEGL KKFKLT+T+STSNMHLFDA G 
Subjt:  EVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGV

Query:  IKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETDEAEE
         KK+DTPEQILEEFFPLRL++YEK K  +L NL   LL L+NKVRFIL VVN EI VSNRKK +L  EL+ KGFTP P+K KS +P++AGA+++  E +E
Subjt:  IKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETDEAEE

Query:  SPE--------VVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLK
          E         V+G    DY+ LL+LPIGTLT+E VQ+L +++ + + E + L      SLWL DLD  EK+LDE+D   A+    R  Q  K  N   
Subjt:  SPE--------VVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLK

Query:  PKISRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMET
         K ++  P+  +N+KK  +VE   ++      +         V KPKG+AAP+K   K          + +D++  L++RLAAY IESS E S+  AME+
Subjt:  PKISRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMET

Query:  EVQEVQAAKKKEPSKRAPAKKKTTA---KSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGK------TTKAPAAGGK--------LGQKL
        E  + +AA KK+ +KR  AKKK++    +S   +  +D DDDD + +EV  +AA     +GGRK AA N K        KAPAA  K         GQKL
Subjt:  EVQEVQAAKKKEPSKRAPAKKKTTA---KSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGK------TTKAPAAGGK--------LGQKL

Query:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGF--QPAIGRSRRANRTQVRYVLSDSDDEAVSQD
        +T ML+PAE +G SPEKKVRK+R SPFNKKSGS+LGRA   ++   I D      S +  + +EV     QPA  R +RANRTQ++Y LS+S+ E   +D
Subjt:  ITQMLEPAENSGISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGF--QPAIGRSRRANRTQVRYVLSDSDDEAVSQD

Query:  SDFDEDEASLDED
        SD D + +  +ED
Subjt:  SDFDEDEASLDED

P08096 DNA topoisomerase 2

0.0e+00

46.8

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Query:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVY--ENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPS
        M   ++ PL  +N  N +SN       +   YQ+ +  EH+L RPDTY+GSIE  T  +WV+  E +K+ +++++YVPGLYKIFDEI+VNAADNK RDP+
Subjt:  MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVY--ENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPS

Query:  MDSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKK
        M+++KV +D E N IS++NNG G+P+EIH +EK+Y+PELIFG+LLTSSNYDD +KK TGGRNGYGAKL NIFSTEFV+ETAD  R+KKYKQ + DNM +K
Subjt:  MDSVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKK

Query:  SEPIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEI
        SEP+IT  K+ D +T++TFKPDLAKF M  ++DD+V+++K+R+ D+AG + +T KV LN +R+ +  F+ YV++YL S +    EPP+  +   N+RW++
Subjt:  SEPIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEI

Query:  VVTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLK
           +S+GQF+QVSFVN I+TI+GGTHV Y+ N+I + +   V K+NK A VKA  +KNY+ VF+N  I+NPSFDSQTKETLT + ++FGS C L+ +FLK
Subjt:  VVTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLK

Query:  NVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ
         +  KS +++ VL +   K  + L K DG    +I+G+ KLEDAN AG K S KC LILTEGDSAK+LA++GL VVGRD+YGVFPLRGKLLNVREAS  Q
Subjt:  NVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ

Query:  ITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKES
        I  NKEIQ IK+I+G    K Y + K LRYGHLMIMTDQDHDGSHIKGL+IN++ S +PSLL++P FL++FITPI+K T  N  V +FYT+PEYE WKE+
Subjt:  ITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKES

Query:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQ
           N  GW IKYYKGLGTS   + + YF  L +H K F    + D E IE+AF+KKK + RK WLR + PG ++D T   I   DF+N+ELI FSMAD  
Subjt:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQ

Query:  RSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN
        RSIPS+VDGLKPGQRK+++  FKRN + E KVS+ +GYV+  +AYHHGE S+  TI+ +AQ+FVGSNNINLL+PNGQFGTR+ GGK+ ++SRY+ T LS 
Subjt:  RSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLSN

Query:  VTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYT
        + R LF  +DD+LLNY N++GQ IEP +Y+PI+P VLVNG+EGIGTGWS+++PNYNP+DI  N+R ML+GE +  M PWYRGF G+I K A       Y 
Subjt:  VTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTYT

Query:  ISGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL
        ISGII ++ +  + I ELP+R WT D K++L+     A     EK  K  FI   + H  +  V  +V LTE  M  A+ E L+ KFKL+ T +TSNM  
Subjt:  ISGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMHL

Query:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPF--PKKTKSVEPEIAGAS
        FDA+G IKKYD+ E IL EF+ +RL  Y++RK  +++ LE    +  N+ RFI  ++  E+ VS +KK DL  EL+ K F P   PKK   V+ E+    
Subjt:  FDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPF--PKKTKSVEPEIAGAS

Query:  NETDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLE----KELDEVDRNDAQTMELRKQQRDKAN
        N   E E+S +V + E    Y YLL++P+ +LT E+  EL   +D++  E+D L K TPK LWL+DLD+ E    K +D++ R   + +E  +  RD  N
Subjt:  NETDEAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLE----KELDEVDRNDAQTMELRKQQRDKAN

Query:  -NDLKPKISRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEV
            KP+      + PR    +S+   V +   +    +TT      ++    + A  K P K      V  ED+   +   ++R++      S +  + 
Subjt:  -NDLKPKISRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEV

Query:  SAMETEVQEVQAAKKKEPSK---RAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQ---AAKKGGGRGGRKAAAANGKTTKAP-----AAGGKLGQKLI
              V    A  KK   K    A  + + T K    +I   +D+DD     + P    + K      G+KA++   ++ +         G     K  
Subjt:  SAMETEVQEVQAAKKKEPSK---RAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQ---AAKKGGGRGGRKAAAANGKTTKAP-----AAGGKLGQKLI

Query:  TQMLEPAENSGISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVM
        +   EP E+S  SP +K R  R +    K+   +  + +  +E  ++D+  ++
Subjt:  TQMLEPAENSGISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVM

P30182 DNA topoisomerase 2

0.0e+00

63.79

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Query:  KRPLQNSNTANVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSN ANV   PA  +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNTANVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADG+RLKKYKQVF +NMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPP-KRYHIKPNERWEIV
        P+ITKC + +NWT+VTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+  + E P  R   K N+RWE+ 
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPP-KRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKN
        V+LSEGQFQQVSFVN IATIKGGTHV+Y+T+QI N+++ AVNKKNKNANVKAHNVKN+LWVF+NALIDNP+FDSQTKETLT R +SFGS CEL+ +FLK 
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKN

Query:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE
        T NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT K GT  VLSFY+MPEYE WKE
Subjt:  TENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADL
        SL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ    + YSDFVNKELILFSMADL
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADL

Query:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTY
         VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I+ NVRR+L+GE+M+PMDPWYRGF GTIEKTA+KEGG TY
Subjt:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTY

Query:  TISGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMH
        TI+G+ EEV +TT+RI ELP+RRW  DYK+FL S+     K D       PF +    ++D+K V  D+ L+EENML A QEG  KKFKLTTT++TSNMH
Subjt:  TISGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMH

Query:  LFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASN
        LFD  GVIKKY TPEQILEEFF LR E+YEKRK  ++ N+E+ELLKLENK RFILAV++ EI V+ RKK D+  +L+ KGFTPFP+K +SVE  IAGA +
Subjt:  LFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASN

Query:  ETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMEL--RKQQR
        + D AEE  E++            S+Y+YLLA+ I +LTIEKV+EL  DRDK+   V D++K TPKSLWL+DL+SL+KEL+++D  DAQ  +     Q++
Subjt:  ETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMEL--RKQQR

Query:  DKANNDLKPKISRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGK-AAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPE
         +A +    K+ R APK P   KKT+   + +E+ + +YS+  T+     VVKPK +  A +KA   +  +A+    D D+ V E+         +    
Subjt:  DKANNDLKPKISRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGK-AAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPE

Query:  PSEVSAMETEVQEVQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLI--TQMLE
         +     E E+ ++     +     APA    TA++++    DD+DDD   + EV P        +GGRK AA   K  K PAA  K G++ +  T++L 
Subjt:  PSEVSAMETEVQEVQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLI--TQMLE

Query:  PAENSGISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEA
             G+SPEKKVRK+R+SPFNKKS S++ R  + +EE+  E+   V G++SSE S    G   AI R +RANR ++ YVLSDS+ E+ + DS+FD+ E 
Subjt:  PAENSGISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEA

Query:  SLDED
          D++
Subjt:  SLDED

Q02880 DNA topoisomerase 2-beta

0.0e+00

48.66

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Query:  QNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEND-KMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDV
        + S TAN   N +  K ++E +YQKK+QLEHILLRPDTY+GS+E  TQ +WVY+ D  M  R +++VPGLYKIFDEILVNAADNKQRD +M  +KV+ID 
Subjt:  QNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYEND-KMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDV

Query:  EQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPIITKCKE
        E N IS++NNG G+PV  H+ EKVYVP LIFG LLTSSNYDD EKK TGGRNGYGAKL NIFST+F +ETA       +KQ + +NM K SE  I K  +
Subjt:  EQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPIITKCKE

Query:  GDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAG-CLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVVTLSEGQF
        G+++T +TF+PDL+KF M  L+ D+VALM +R  DLAG C G  VKV  NG+++PV  F+ YVDLY+K          K  H   NERW++ +TLSE  F
Subjt:  GDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAG-CLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVVTLSEGQF

Query:  QQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNK-NANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNVATKSGI
        QQ+SFVN IAT KGG HV+Y+ +Q+   ++  V KKNK   +VK   VKN++WVFIN LI+NP+FDSQTKE +T +  SFGS C+L+ +F K  A+  GI
Subjt:  QQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNK-NANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNVATKSGI

Query:  MDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEI
        ++S+L+WV FK    L KK    K  KI GI KL+DAN AGGK+S +CTLILTEGDSAK+LA++GLGV+GRD YGVFPLRGK+LNVREAS KQI EN EI
Subjt:  MDSVLSWVNFKQSKDL-KKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEI

Query:  QYIKQILGLQQGKEYNNA---KALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGN
          I +I+GLQ  K Y++A   K LRYG +MIMTDQD DGSHIKGLLINFIH  WPSLL+   FL EFITPIVKA+ KN   LSFY++PE++ WK+ +  N
Subjt:  QYIKQILGLQQGKEYNNA---KALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGN

Query:  ASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFE-----------PGTHLDQTG-KLIKYSDFVNKELI
           W IKYYKGLGTST+KE +EYF  + +H+  F +    D  AI LAFSKKKI+DRK WL  F            P   L  T  K + Y+DF+NKELI
Subjt:  ASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFE-----------PGTHLDQTG-KLIKYSDFVNKELI

Query:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR
        LFS +D +RSIPS+VDG KPGQRK+LF  FKRN  +E KV+Q +G V+E SAYHHGEQ+L  TI+ +AQ+FVGSNNINLL P GQFGTR HGGKD AS R
Subjt:  LFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSR

Query:  YIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTAT
        YI+T LS + R LFP  DD LL +L +D Q +EP WY+PIIP VL+NG+EGIGTGW+  +PNY+ R+I+ NVRRMLDG    PM P Y+ F GTI++   
Subjt:  YIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTAT

Query:  KEGGTTYTISGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTT
          G   Y +SG I  V   T+ I ELPVR WT  YK+    +  + +  DK  A     I     +  D  V   V +TEE +  A   GL K FKL TT
Subjt:  KEGGTTYTISGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTT

Query:  VSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEP
        ++ ++M LFD  G +KKY+T + IL+EFF LRL +Y  RK  L+  L  E  KL N+ RFIL  +  +I + NR K DL   L  +G+   P K      
Subjt:  VSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEP

Query:  EIAGASNETDEAEESPEVVKGERIS-DYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRD
        E A   +ET    +      G     D+ Y+L + + +LT EKV+EL   RD    EV+DL++ +P  LW  DL +  +ELD+V+           Q+R+
Subjt:  EIAGASNETDEAEESPEVVKGERIS-DYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRD

Query:  KANNDLKPKISRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPS
            D+   +S  A K      K   ++ + E+M + Y          P +      A +K   KKKG     D D     +E  +  +   +E + E +
Subjt:  KANNDLKPKISRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPS

Query:  EVSAMETEVQEVQAAKKKEPSKRAPAKKKTTAKSAQISI------SDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTT
           ++          +KKEP  R      ++ K +   +      SDDE   + +++E +P    +      R+AAA   K T
Subjt:  EVSAMETEVQEVQAAKKKEPSKRAPAKKKTTAKSAQISI------SDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTT

Q55BP5 Probable DNA topoisomerase 2

0.0e+00

47.38

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Query:  EKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVK
        +K     N N     ++ A   K+IEE+YQKK  L+ ILLRPDTY+GS E+  + LWV+E+ +MVHR +S+VPG+YKIFDEILVNAADNKQR+ +M  +K
Subjt:  EKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVK

Query:  VNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPII
        V ID E+  ISV N+G G+P+++H E K+Y+PELIFG+LLTSS+YDD+EK+ TGGRNG+GAKL NIFST+F++E AD +  K YKQ F +NM  K +P I
Subjt:  VNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPII

Query:  TKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVVTLS
        T  +   ++T++TF P+L +F M   +DD+VAL+ KRV D+AGC   T+KV LN + + ++SF+ Y++LY       +   PK Y+ K ++RWE+ VTLS
Subjt:  TKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVVTLS

Query:  -EGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNK-NANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNVA
         E QF QVSFVN I T+KGGTHV +  + I   +   VNKKNK +A++K   +KN+L VF+N LI+NP FDSQTKETLT + +SFGS CE + +F+K V 
Subjt:  -EGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNK-NANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNVA

Query:  -TKSGIMDSVLSWVNFKQSKDLKK--TDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ
         +KSGI+ S+L +  FK    LK+  + G K  K+S I KL+DAN AGG  SE CTLILTEGDSAK+LA AG+ VVG+D YG FPL+GKLLNVR+ S+K 
Subjt:  -TKSGIMDSVLSWVNFKQSKDLKK--TDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQ

Query:  ITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKES
        +  N EI  I  ILGL+ GK Y     LRYGHLMIMTDQDHDGSHIKGL+IN +H FWP+LLR+P FLVEFITPIVK    N   +SFYTMPE+  W+E+
Subjt:  ITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKES

Query:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTG-KLIKYSDFVNKELILFSMADL
           N  GW +KYYKGLGTST  EG+EYF  L +HK DF W D+   + IELAFSK + +DRK W+ +   GT L+Q G K + YSDF+NKEL+LFS+AD 
Subjt:  LRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTG-KLIKYSDFVNKELILFSMADL

Query:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        +RSIP++VDGLK   RK L+  FKRN  KE KV+Q  GYVSEHSAYHHGE SL STI+GMAQ+FVGSNNINLL P G +GTR  GGKD +S+RYI+T+L+
Subjt:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIE-KTATKEGGTT
        ++ R ++  DDD +L+ + +DG+ ++P +Y+P+IP +LVNG  GIGTGWSS +PNYNPRD+I+N+R  +DG+ + P+ PWYRGF G+IE    +K  G  
Subjt:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIE-KTATKEGGTT

Query:  YTISGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSV----TRVASKHDKEKAAKDPFIEQA------------DHHSDDKIVSIDV------------HL
        Y   GI +++SD    I ELP+  WT DY++ LD +    TR   K +KEK A      +A            D   ++K+    V            H 
Subjt:  YTISGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSV----TRVASKHDKEKAAKDPFIEQA------------DHHSDDKIVSIDV------------HL

Query:  TEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVD
          + +    +  ++K FKL +T++ +NM +FD  G I+++ T   + E FFPLR++ Y+ RK  L + L  E  +L NK RFILAVVN+E+ +SN KKVD
Subjt:  TEENMLLAIQEGLKKKFKLTTTVSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVD

Query:  LFHELQAKGFTPFPKK--TKSVEPEIAGASNETDE------AEESPEVVKGERISD---YEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKS
        L ++L+   F     K   KS   +I    N  DE      ++E  +  + E+  D   Y+YLL+LP+ +LT+E+V++L  +RD  K E D L     + 
Subjt:  LFHELQAKGFTPFPKK--TKSVEPEIAGASNETDE------AEESPEVVKGERISD---YEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKS

Query:  LWLNDLDSLEKELDEVDRNDA----QTMELRKQQRDKA---NNDLKPKISRNAPKAPRNS--KKTSNVETVTESM----------DTTYSSTTTEVANN-
        ++  DLD+LEK LD+ D  D     QT  L+K+ + KA      +  K+ ++  +AP     K T  + T T+S           DTT +ST+T  ++N 
Subjt:  LWLNDLDSLEKELDEVDRNDA----QTMELRKQQRDKA---NNDLKPKISRNAPKAPRNS--KKTSNVETVTESM----------DTTYSSTTTEVANN-

Query:  -PVVKPKGKAAPRKAPAKKKGKAAVPDED---DDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQEVQAAKKKEPSKR--APAKKKTT-----AKSAQI
         P+     K   +  PA KK      D D   DDD V+  K +    K     E S+ S  E++ +  Q +  + P KR  AP KK TT     A +++ 
Subjt:  -PVVKPKGKAAPRKAPAKKKGKAAVPDED---DDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQEVQAAKKKEPSKR--APAKKKTT-----AKSAQI

Query:  SISDDEDDDDFEIK
         + DD+  DD  IK
Subjt:  SISDDEDDDDFEIK

Arabidopsis top hits

e value

%identity

Alignment

AT3G10270.1 DNA GYRASE B1

2.8e-22

23.77

Show/hide

Query:  GLYKIFDEILVNAADNKQRDPSMDSVKVNIDV---EQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFS
        GL+ +  EIL NA D  Q           IDV     + +S+ +NG G+P ++H        E +   L     +         +GG +G G  + N  S
Subjt:  GLYKIFDEILVNAADNKQRDPSMDSVKVNIDV---EQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFS

Query:  TEF-VIETADGRRLKKYKQVFNDNMGKKSEPIIT-KC------KEGDNWTRVTFKPDLAKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVP
            VI   DG    +++Q ++     + +P+ T  C        G   T + F PD   F      + + +A   + +  L   +  ++K E +     
Subjt:  TEF-VIETADGRRLKKYKQVFNDNMGKKSEPIIT-KC------KEGDNWTRVTFKPDLAKFNMT-HLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVP

Query:  VKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVVTLSEGQFQ---------QVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHN
        V S   Y     +  S    +  K  H     R EI  +  +   Q          + + N I TI GGTH+E +   +    + ++ KK K   VK + 
Subjt:  VKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVVTLSEGQFQ---------QVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHN

Query:  VKNYLWV-------------------------------------FINALIDNPSFDSQTKETL----------TKRANSFGSACELTPEFLKNVATKSGI
        + +  W+                                      ++  + NP F+ QTK  L                     EL P+ L+++ +KS  
Subjt:  VKNYLWV-------------------------------------FINALIDNPSFDSQTKETL----------TKRANSFGSACELTPEFLKNVATKSGI

Query:  MDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEI
        +++  + +  K++++L ++    K+  + G  KL D +      SE   + + EGDSA   A  G     R F  + PLRGK+LN+       + +N+EI
Subjt:  MDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEI

Query:  QYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNASG
        Q +   LGL    E  N + LRY  ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K   +       Y     +    S  GNAS 
Subjt:  QYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNASG

Query:  WSIKYYKGLG
        ++I+ +KGLG
Subjt:  WSIKYYKGLG

AT3G23890.1 topoisomerase II

0.0e+00

63.79

Show/hide

Query:  KRPLQNSNTANVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSN ANV   PA  +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNTANVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADG+RLKKYKQVF +NMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPP-KRYHIKPNERWEIV
        P+ITKC + +NWT+VTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+  + E P  R   K N+RWE+ 
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPP-KRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKN
        V+LSEGQFQQVSFVN IATIKGGTHV+Y+T+QI N+++ AVNKKNKNANVKAHNVKN+LWVF+NALIDNP+FDSQTKETLT R +SFGS CEL+ +FLK 
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKN

Query:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE
        T NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT K GT  VLSFY+MPEYE WKE
Subjt:  TENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADL
        SL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ    + YSDFVNKELILFSMADL
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADL

Query:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTY
         VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I+ NVRR+L+GE+M+PMDPWYRGF GTIEKTA+KEGG TY
Subjt:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTY

Query:  TISGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMH
        TI+G+ EEV +TT+RI ELP+RRW  DYK+FL S+     K D       PF +    ++D+K V  D+ L+EENML A QEG  KKFKLTTT++TSNMH
Subjt:  TISGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMH

Query:  LFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASN
        LFD  GVIKKY TPEQILEEFF LR E+YEKRK  ++ N+E+ELLKLENK RFILAV++ EI V+ RKK D+  +L+ KGFTPFP+K +SVE  IAGA +
Subjt:  LFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASN

Query:  ETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMEL--RKQQR
        + D AEE  E++            S+Y+YLLA+ I +LTIEKV+EL  DRDK+   V D++K TPKSLWL+DL+SL+KEL+++D  DAQ  +     Q++
Subjt:  ETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMEL--RKQQR

Query:  DKANNDLKPKISRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGK-AAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPE
         +A +    K+ R APK P   KKT+   + +E+ + +YS+  T+     VVKPK +  A +KA   +  +A+    D D+ V E+         +    
Subjt:  DKANNDLKPKISRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGK-AAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPE

Query:  PSEVSAMETEVQEVQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLI--TQMLE
         +     E E+ ++     +     APA    TA++++    DD+DDD   + EV P        +GGRK AA   K  K PAA  K G++ +  T++L 
Subjt:  PSEVSAMETEVQEVQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLI--TQMLE

Query:  PAENSGISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEA
             G+SPEKKVRK+R+SPFNKKS S++ R  + +EE+  E+   V G++SSE S    G   AI R +RANR ++ YVLSDS+ E+ + DS+FD+ E 
Subjt:  PAENSGISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEA

Query:  SLDED
          D++
Subjt:  SLDED

AT3G23890.2 topoisomerase II

0.0e+00

64.19

Show/hide

Query:  KRPLQNSNTANVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD
        K PLQNSN ANV   PA  +     KTIEEMYQKKSQLEHILLRPDTY+GSIEKHTQ LWVYE D+MV R ++YVPGLYKIFDEILVNAADNKQRD  MD
Subjt:  KRPLQNSNTANVDSNPAGPK-----KTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMD

Query:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE
        SV+V IDVEQN ISV N+G GVPVEIHQEE +YVPE+IFGHLLTSSNYDD  KKTTGGRNGYGAKLTNIFSTEF+IETADG+RLKKYKQVF +NMGKKSE
Subjt:  SVKVNIDVEQNCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSE

Query:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPP-KRYHIKPNERWEIV
        P+ITKC + +NWT+VTFKPDL KFNMT LEDDVVALM KRV D+AGCLGK+VKVELNG+++PVKSF DYVDLYL +A+  + E P  R   K N+RWE+ 
Subjt:  PIITKCKEGDNWTRVTFKPDLAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPP-KRYHIKPNERWEIV

Query:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKN
        V+LSEGQFQQVSFVN IATIKGGTHV+Y+T+QI N+++ AVNKKNKNANVKAHNVKN+LWVF+NALIDNP+FDSQTKETLT R +SFGS CEL+ +FLK 
Subjt:  VTLSEGQFQQVSFVNGIATIKGGTHVEYITNQIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKN

Query:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI
        V  KSG+++++LSW +FKQ+KDLKK+DGAKT ++  +EKL+DA  AGGKNS  CTLILTEGDSAK+LA+AG  V+G ++ GVFPLRGKLLNVREAS+ QI
Subjt:  VATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQI

Query:  TENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE
        T NKEI+ +K+ILGL+Q  +Y N  +LRYG +MIMTDQDHDGSHIKGLLINFIHSFWPSLL+VPSFLVEFITPIVKAT K GT  VLSFY+MPEYE WKE
Subjt:  TENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGT--VLSFYTMPEYESWKE

Query:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADL
        SL+GNA+GW IKYYKGLGTST++EG+EYF  L  HKKDF+W+D+ DGEAIELAFSKKKIE RKNWL  + PG HLDQ    + YSDFVNKELILFSMADL
Subjt:  SLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRKNWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADL

Query:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS
        QRSIPSMVDGLKPGQRKILF +FK+   KE KV+Q  GYVS  SAYHHGEQSLAS IIGMAQD+VGSNNINLLLPNGQFGTR  GGKD AS+RYI+TKLS
Subjt:  QRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLLPNGQFGTRNHGGKDHASSRYIYTKLS

Query:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTY
         VTR LFPKDDD LL+YLNEDGQ IEPTWYMPIIPTVLVNG+EGIGTGWS+++PNYNPR+I+ NVRR+L+GE+M+PMDPWYRGF GTIEKTA+KEGG TY
Subjt:  NVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRGFSGTIEKTATKEGGTTY

Query:  TISGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMH
        TI+G+ EEV +TT+RI ELP+RRW  DYK+FL S+     K D       PF +    ++D+K V  D+ L+EENML A QEG  KKFKLTTT++TSNMH
Subjt:  TISGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTTVSTSNMH

Query:  LFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASN
        LFD  GVIKKY TPEQILEEFF LR E+YEKRK  ++ N+E+ELLKLENK RFILAV++ EI V+ RKK D+  +L+ KGFTPFP+K +SVE  IAGA +
Subjt:  LFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASN

Query:  ETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMEL--RKQQR
        + D AEE  E++            S+Y+YLLA+ I +LTIEKV+EL  DRDK+   V D++K TPKSLWL+DL+SL+KEL+++D  DAQ  +     Q++
Subjt:  ETDEAEESPEVVKGERI-------SDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMEL--RKQQR

Query:  DKANNDLKPKISRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGK-AAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPE
         +A +    K+ R APK P   KKT+   + +E+ + +YS+  T+     VVKPKG+  A +KAPA  K       E ++DE+L+L  RLA Y   S+P 
Subjt:  DKANNDLKPKISRNAPKAPRNSKKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGK-AAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPE

Query:  PSEVSAMETEVQEVQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLI--TQMLE
         S                            KT   S  I++ DD+DD   E+  V          +GGRK AA   K  K PAA  K G++ +  T++L 
Subjt:  PSEVSAMETEVQEVQAAKKKEPSKRAPAKKKTTAKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLI--TQMLE

Query:  PAENSGISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEA
             G+SPEKKVRK+R+SPFNKKS S++ R  + +EE+  E+   V G++SSE S    G   AI R +RANR ++ YVLSDS+ E+ + DS+FD+ E 
Subjt:  PAENSGISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIEDEGKVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEA

Query:  SLDED
          D++
Subjt:  SLDED

AT5G04130.1 DNA GYRASE B2

1.0e-27

24.76

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Query:  EMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVE-QNCISVFNNGDGVPVEIHQ
        E  Q    L+ +  RP  Y+GS                         GL+ +  EIL NA D  Q   +    KV++ +     +SV +NG G+P ++H 
Subjt:  EMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVE-QNCISVFNNGDGVPVEIHQ

Query:  EEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPIIT-KCK------EGDNWTRVTFKP
          K    E +   L     +  T      +GG +G G  + N  S    +E +  R   ++KQ ++     + +PI T  C+      +G   T + F P
Subjt:  EEKVYVPELIFGHLLTSSNYDDTEK--KTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPIIT-KCK------EGDNWTRVTFKP

Query:  DLAKFNMTHLEDDVVALMKKRVLDLAGCLGK-TVKVELNGQRVPVKSFQDYVDL-YLKSASSFQAEPPKRYHIKPNERWEIVVTLSEGQFQ---------
        D   F  T +E D   +   R+ +LA    K T+ ++          + +Y     L    S+        H     R EI     +   Q         
Subjt:  DLAKFNMTHLEDDVVALMKKRVLDLAGCLGK-TVKVELNGQRVPVKSFQDYVDL-YLKSASSFQAEPPKRYHIKPNERWEIVVTLSEGQFQ---------

Query:  QVSFVNGIATIKGGTHVEYITNQIANYVMTAVNK----KNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETL----------TKRANSFGSACELTP
         + + N I TI GGTH+E +   +   + T   K    K K+ ++   +V+  L   ++  + NP F+ QTK  L                     EL P
Subjt:  QVSFVNGIATIKGGTHVEYITNQIANYVMTAVNK----KNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETL----------TKRANSFGSACELTP

Query:  EFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVRE
        + L+++ +KS  +++  + +  K++++L ++    K+  + G  KL D +    + SE   + + EGDSA   A  G     R F  + PLRGK+LN+  
Subjt:  EFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGA-KTEKISGIEKLEDANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVRE

Query:  ASSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYE
             + +N+EIQ +   LGL    E    + LRY  ++I+TD D DG+HI+ LL+ F   +  +L       V  + P+ K   +       Y   + +
Subjt:  ASSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLINFIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYE

Query:  SWKESLRGNASGWSIKYYKGLG
            +   NAS ++I+ +KGLG
Subjt:  SWKESLRGNASGWSIKYYKGLG

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGGTTGTGGAAAAGAAACGGCCACTTCAGAACAGCAACACCGCCAATGTCGACTCCAATCCCGCAGGTCCAAAGAAAACAATCGAAGAAATGTACCAAAAGAAGTCTCA
GCTCGAGCACATTCTTCTCAGGCCCGATACCTATGTCGGATCTATTGAAAAGCATACCCAAAACCTCTGGGTTTACGAGAATGACAAGATGGTCCACCGATCAATCTCTT
ATGTGCCTGGTCTTTACAAGATCTTTGATGAAATCTTGGTCAATGCTGCAGATAATAAGCAGAGAGACCCTTCCATGGATTCTGTCAAGGTCAATATTGATGTCGAGCAG
AACTGTATCAGTGTTTTTAACAATGGAGATGGAGTTCCGGTTGAAATTCATCAGGAAGAGAAGGTTTATGTTCCTGAGTTGATCTTTGGACATTTGTTGACTAGTAGTAA
CTATGATGATACCGAAAAGAAAACCACTGGTGGACGCAATGGGTATGGTGCGAAACTTACCAATATTTTTTCTACTGAATTTGTGATCGAAACGGCTGATGGAAGACGCC
TGAAGAAGTATAAGCAGGTATTCAATGATAACATGGGGAAAAAATCAGAGCCGATTATAACAAAGTGTAAGGAGGGTGATAATTGGACCAGGGTAACTTTTAAGCCGGAC
TTGGCAAAATTTAACATGACCCATCTTGAAGATGATGTTGTTGCACTGATGAAAAAGAGAGTCTTGGATTTGGCTGGATGCCTTGGTAAAACCGTGAAGGTTGAGCTGAA
TGGACAAAGGGTCCCTGTTAAATCATTTCAAGATTATGTAGATCTCTACCTCAAATCAGCATCCTCATTCCAGGCGGAACCTCCCAAAAGGTATCACATTAAGCCTAATG
AGAGATGGGAAATTGTGGTGACCTTAAGTGAGGGCCAGTTCCAACAGGTCAGCTTTGTGAACGGGATTGCAACAATTAAGGGTGGGACTCATGTTGAATACATCACTAAT
CAAATAGCAAATTACGTGATGACTGCTGTAAATAAGAAGAACAAAAATGCTAACGTGAAGGCTCATAATGTGAAGAACTATTTGTGGGTTTTTATCAATGCTCTCATTGA
TAATCCATCGTTCGACTCCCAAACCAAGGAAACTTTGACAAAACGTGCAAACAGTTTCGGTTCTGCATGTGAACTTACGCCAGAATTTTTGAAGAATGTGGCCACAAAAT
CTGGAATTATGGACAGCGTTCTCTCATGGGTTAATTTCAAGCAAAGCAAAGATTTGAAGAAAACGGATGGAGCAAAAACAGAAAAGATTAGTGGTATCGAAAAGTTAGAG
GATGCCAATTGTGCTGGAGGGAAGAACTCAGAAAAATGTACCTTAATTTTGACGGAAGGAGATTCAGCTAAGGCCCTTGCAATGGCTGGGCTCGGTGTAGTAGGACGAGA
CTTTTATGGTGTATTCCCACTCAGAGGTAAATTGCTCAATGTGAGGGAAGCAAGTAGTAAACAAATCACAGAGAATAAAGAAATTCAGTACATCAAGCAAATTCTTGGAC
TTCAGCAAGGGAAGGAATACAACAATGCTAAGGCTTTGAGATACGGTCATTTGATGATTATGACCGATCAGGACCATGATGGCTCACACATTAAAGGACTCTTGATCAAC
TTTATTCATTCTTTTTGGCCTTCTCTCCTAAGAGTGCCATCGTTCTTGGTTGAATTCATAACGCCAATTGTCAAGGCTACTCATAAGAATGGAACTGTTTTATCTTTCTA
TACCATGCCCGAGTACGAATCCTGGAAAGAGAGCTTGAGGGGCAATGCAAGTGGCTGGTCAATCAAGTACTATAAGGGGTTGGGAACAAGCACATCAAAAGAAGGGAGAG
AGTACTTTGAACAGCTAACAAAGCACAAGAAAGATTTTATTTGGCAAGATGATAACGACGGGGAGGCCATTGAGCTTGCTTTCAGTAAGAAGAAGATTGAAGATAGAAAG
AATTGGCTCCGTCAATTTGAGCCTGGTACCCATCTAGATCAGACAGGAAAATTGATCAAATACAGCGACTTCGTTAACAAGGAGCTTATATTATTTTCAATGGCTGATTT
ACAAAGGTCTATTCCCTCAATGGTTGATGGCCTTAAGCCTGGCCAAAGGAAGATCCTTTTCTGTTCTTTCAAGAGGAACTTTATCAAAGAAGCAAAGGTTTCACAATTTT
CCGGTTACGTATCTGAGCACTCTGCTTATCATCATGGTGAGCAGAGTCTTGCTAGTACCATCATTGGAATGGCACAGGACTTTGTTGGCAGTAACAACATTAATCTTCTT
CTACCAAATGGACAGTTTGGCACACGGAACCATGGAGGCAAAGATCATGCAAGTTCTAGGTACATTTACACTAAACTTTCAAATGTCACACGGTTCCTTTTCCCGAAAGA
TGATGACAAGCTTCTTAACTACTTAAATGAAGATGGCCAGTCGATTGAACCAACCTGGTATATGCCTATCATCCCAACCGTTCTTGTCAATGGAAGTGAAGGAATTGGAA
CTGGGTGGAGTTCATACGTTCCAAACTATAATCCTAGAGACATCATTAGAAATGTCAGACGCATGTTGGATGGTGAAACGATGTTGCCGATGGATCCATGGTATAGAGGT
TTTTCAGGAACTATAGAGAAAACTGCCACTAAAGAAGGAGGTACTACTTACACTATTAGTGGAATTATAGAGGAAGTCAGTGATACAACGTTGAGAATAGTTGAATTGCC
AGTCCGCCGATGGACTAGTGACTACAAGGACTTTCTCGACTCTGTCACAAGAGTTGCATCAAAGCATGACAAAGAAAAAGCAGCAAAGGATCCTTTTATTGAGCAAGCTG
ACCACCACAGCGATGACAAAATTGTTTCCATTGATGTTCACTTAACAGAGGAAAACATGTTATTGGCCATCCAGGAAGGTTTGAAGAAGAAATTCAAACTAACTACAACT
GTCAGCACTAGCAACATGCACCTGTTTGATGCAAATGGCGTCATTAAGAAATATGACACCCCAGAACAAATTCTTGAGGAATTTTTCCCCCTTAGACTTGAATTCTACGA
GAAAAGGAAGAGAATTCTTTTGGATAACCTTGAAATGGAGTTGCTTAAACTGGAAAACAAGGTGAGGTTCATTCTTGCTGTTGTGAATGAAGAGATAAAAGTAAGCAATA
GAAAAAAGGTTGATTTGTTCCACGAGCTTCAAGCGAAAGGCTTTACACCCTTTCCAAAGAAGACTAAATCTGTTGAGCCGGAGATTGCTGGGGCATCTAATGAAACTGAT
GAAGCAGAGGAGAGCCCGGAAGTGGTAAAAGGCGAACGAATTAGTGATTATGAGTATCTACTTGCTCTGCCAATTGGAACCTTGACCATCGAGAAGGTACAGGAGCTATG
TAATGATAGAGACAAGCTGAAAGGAGAAGTGGACGATCTGAGGAAGGCAACCCCCAAATCTTTGTGGCTGAATGACCTTGATTCTCTTGAGAAAGAGCTTGATGAGGTGG
ATAGAAATGATGCTCAGACGATGGAGTTAAGAAAACAACAGCGAGACAAAGCAAATAACGATTTAAAGCCAAAAATCTCAAGAAATGCACCAAAAGCTCCACGTAACAGT
AAGAAAACCAGCAATGTGGAAACTGTCACCGAAAGTATGGACACAACATATAGTTCTACAACAACGGAAGTTGCAAATAACCCGGTGGTGAAGCCAAAAGGCAAGGCAGC
TCCAAGAAAAGCTCCTGCTAAGAAGAAGGGTAAAGCAGCAGTTCCTGACGAGGACGACGATGATGAAGTCCTCGAGCTTAAAGATCGTCTTGCTGCCTACAAAATTGAGT
CATCTCCTGAACCATCAGAAGTTTCAGCCATGGAAACTGAAGTGCAGGAAGTACAAGCGGCCAAGAAGAAAGAACCTAGCAAGAGAGCACCTGCCAAGAAGAAAACTACT
GCAAAGTCAGCTCAGATCTCTATTAGTGATGACGAGGACGACGACGATTTTGAAATAAAGGAGGTAGACCCTCAGGCAGCCAAGAAGGGAGGAGGAAGAGGAGGAAGAAA
GGCAGCTGCAGCAAATGGCAAAACCACCAAGGCCCCTGCTGCAGGAGGGAAGTTGGGGCAGAAACTGATAACTCAAATGCTAGAACCAGCAGAGAACTCCGGCATCTCAC
CAGAAAAGAAAGTGAGGAAGATAAGAGCATCACCTTTCAACAAGAAAAGTGGCTCTTTATTGGGAAGAGCAATAGAGGAAGAAGAAGAGGACGGAATTGAAGATGAAGGG
AAGGTGATGGGTTCGGCTTCTTCCGAGACTAGTGAAGAAGTGGCCGGGTTTCAGCCGGCAATAGGAAGATCACGGAGAGCAAACAGAACACAGGTCAGGTATGTGCTTAG
TGATTCAGATGATGAGGCAGTTTCTCAGGATTCAGACTTTGATGAAGACGAAGCCAGCCTTGATGAAGATTGA

mRNA sequence

Show/hide mRNA sequence

ACCATCTCTGTGTCTTCTCTCTCTCAACAACATCTCCTTGTCTTTTCTCTCTCGCTCTCTCAAGAACAGGTTCTTCCGATCACCATGGTTGTGGAAAAGAAACGGCCACT
TCAGAACAGCAACACCGCCAATGTCGACTCCAATCCCGCAGGTCCAAAGAAAACAATCGAAGAAATGTACCAAAAGAAGTCTCAGCTCGAGCACATTCTTCTCAGGCCCG
ATACCTATGTCGGATCTATTGAAAAGCATACCCAAAACCTCTGGGTTTACGAGAATGACAAGATGGTCCACCGATCAATCTCTTATGTGCCTGGTCTTTACAAGATCTTT
GATGAAATCTTGGTCAATGCTGCAGATAATAAGCAGAGAGACCCTTCCATGGATTCTGTCAAGGTCAATATTGATGTCGAGCAGAACTGTATCAGTGTTTTTAACAATGG
AGATGGAGTTCCGGTTGAAATTCATCAGGAAGAGAAGGTTTATGTTCCTGAGTTGATCTTTGGACATTTGTTGACTAGTAGTAACTATGATGATACCGAAAAGAAAACCA
CTGGTGGACGCAATGGGTATGGTGCGAAACTTACCAATATTTTTTCTACTGAATTTGTGATCGAAACGGCTGATGGAAGACGCCTGAAGAAGTATAAGCAGGTATTCAAT
GATAACATGGGGAAAAAATCAGAGCCGATTATAACAAAGTGTAAGGAGGGTGATAATTGGACCAGGGTAACTTTTAAGCCGGACTTGGCAAAATTTAACATGACCCATCT
TGAAGATGATGTTGTTGCACTGATGAAAAAGAGAGTCTTGGATTTGGCTGGATGCCTTGGTAAAACCGTGAAGGTTGAGCTGAATGGACAAAGGGTCCCTGTTAAATCAT
TTCAAGATTATGTAGATCTCTACCTCAAATCAGCATCCTCATTCCAGGCGGAACCTCCCAAAAGGTATCACATTAAGCCTAATGAGAGATGGGAAATTGTGGTGACCTTA
AGTGAGGGCCAGTTCCAACAGGTCAGCTTTGTGAACGGGATTGCAACAATTAAGGGTGGGACTCATGTTGAATACATCACTAATCAAATAGCAAATTACGTGATGACTGC
TGTAAATAAGAAGAACAAAAATGCTAACGTGAAGGCTCATAATGTGAAGAACTATTTGTGGGTTTTTATCAATGCTCTCATTGATAATCCATCGTTCGACTCCCAAACCA
AGGAAACTTTGACAAAACGTGCAAACAGTTTCGGTTCTGCATGTGAACTTACGCCAGAATTTTTGAAGAATGTGGCCACAAAATCTGGAATTATGGACAGCGTTCTCTCA
TGGGTTAATTTCAAGCAAAGCAAAGATTTGAAGAAAACGGATGGAGCAAAAACAGAAAAGATTAGTGGTATCGAAAAGTTAGAGGATGCCAATTGTGCTGGAGGGAAGAA
CTCAGAAAAATGTACCTTAATTTTGACGGAAGGAGATTCAGCTAAGGCCCTTGCAATGGCTGGGCTCGGTGTAGTAGGACGAGACTTTTATGGTGTATTCCCACTCAGAG
GTAAATTGCTCAATGTGAGGGAAGCAAGTAGTAAACAAATCACAGAGAATAAAGAAATTCAGTACATCAAGCAAATTCTTGGACTTCAGCAAGGGAAGGAATACAACAAT
GCTAAGGCTTTGAGATACGGTCATTTGATGATTATGACCGATCAGGACCATGATGGCTCACACATTAAAGGACTCTTGATCAACTTTATTCATTCTTTTTGGCCTTCTCT
CCTAAGAGTGCCATCGTTCTTGGTTGAATTCATAACGCCAATTGTCAAGGCTACTCATAAGAATGGAACTGTTTTATCTTTCTATACCATGCCCGAGTACGAATCCTGGA
AAGAGAGCTTGAGGGGCAATGCAAGTGGCTGGTCAATCAAGTACTATAAGGGGTTGGGAACAAGCACATCAAAAGAAGGGAGAGAGTACTTTGAACAGCTAACAAAGCAC
AAGAAAGATTTTATTTGGCAAGATGATAACGACGGGGAGGCCATTGAGCTTGCTTTCAGTAAGAAGAAGATTGAAGATAGAAAGAATTGGCTCCGTCAATTTGAGCCTGG
TACCCATCTAGATCAGACAGGAAAATTGATCAAATACAGCGACTTCGTTAACAAGGAGCTTATATTATTTTCAATGGCTGATTTACAAAGGTCTATTCCCTCAATGGTTG
ATGGCCTTAAGCCTGGCCAAAGGAAGATCCTTTTCTGTTCTTTCAAGAGGAACTTTATCAAAGAAGCAAAGGTTTCACAATTTTCCGGTTACGTATCTGAGCACTCTGCT
TATCATCATGGTGAGCAGAGTCTTGCTAGTACCATCATTGGAATGGCACAGGACTTTGTTGGCAGTAACAACATTAATCTTCTTCTACCAAATGGACAGTTTGGCACACG
GAACCATGGAGGCAAAGATCATGCAAGTTCTAGGTACATTTACACTAAACTTTCAAATGTCACACGGTTCCTTTTCCCGAAAGATGATGACAAGCTTCTTAACTACTTAA
ATGAAGATGGCCAGTCGATTGAACCAACCTGGTATATGCCTATCATCCCAACCGTTCTTGTCAATGGAAGTGAAGGAATTGGAACTGGGTGGAGTTCATACGTTCCAAAC
TATAATCCTAGAGACATCATTAGAAATGTCAGACGCATGTTGGATGGTGAAACGATGTTGCCGATGGATCCATGGTATAGAGGTTTTTCAGGAACTATAGAGAAAACTGC
CACTAAAGAAGGAGGTACTACTTACACTATTAGTGGAATTATAGAGGAAGTCAGTGATACAACGTTGAGAATAGTTGAATTGCCAGTCCGCCGATGGACTAGTGACTACA
AGGACTTTCTCGACTCTGTCACAAGAGTTGCATCAAAGCATGACAAAGAAAAAGCAGCAAAGGATCCTTTTATTGAGCAAGCTGACCACCACAGCGATGACAAAATTGTT
TCCATTGATGTTCACTTAACAGAGGAAAACATGTTATTGGCCATCCAGGAAGGTTTGAAGAAGAAATTCAAACTAACTACAACTGTCAGCACTAGCAACATGCACCTGTT
TGATGCAAATGGCGTCATTAAGAAATATGACACCCCAGAACAAATTCTTGAGGAATTTTTCCCCCTTAGACTTGAATTCTACGAGAAAAGGAAGAGAATTCTTTTGGATA
ACCTTGAAATGGAGTTGCTTAAACTGGAAAACAAGGTGAGGTTCATTCTTGCTGTTGTGAATGAAGAGATAAAAGTAAGCAATAGAAAAAAGGTTGATTTGTTCCACGAG
CTTCAAGCGAAAGGCTTTACACCCTTTCCAAAGAAGACTAAATCTGTTGAGCCGGAGATTGCTGGGGCATCTAATGAAACTGATGAAGCAGAGGAGAGCCCGGAAGTGGT
AAAAGGCGAACGAATTAGTGATTATGAGTATCTACTTGCTCTGCCAATTGGAACCTTGACCATCGAGAAGGTACAGGAGCTATGTAATGATAGAGACAAGCTGAAAGGAG
AAGTGGACGATCTGAGGAAGGCAACCCCCAAATCTTTGTGGCTGAATGACCTTGATTCTCTTGAGAAAGAGCTTGATGAGGTGGATAGAAATGATGCTCAGACGATGGAG
TTAAGAAAACAACAGCGAGACAAAGCAAATAACGATTTAAAGCCAAAAATCTCAAGAAATGCACCAAAAGCTCCACGTAACAGTAAGAAAACCAGCAATGTGGAAACTGT
CACCGAAAGTATGGACACAACATATAGTTCTACAACAACGGAAGTTGCAAATAACCCGGTGGTGAAGCCAAAAGGCAAGGCAGCTCCAAGAAAAGCTCCTGCTAAGAAGA
AGGGTAAAGCAGCAGTTCCTGACGAGGACGACGATGATGAAGTCCTCGAGCTTAAAGATCGTCTTGCTGCCTACAAAATTGAGTCATCTCCTGAACCATCAGAAGTTTCA
GCCATGGAAACTGAAGTGCAGGAAGTACAAGCGGCCAAGAAGAAAGAACCTAGCAAGAGAGCACCTGCCAAGAAGAAAACTACTGCAAAGTCAGCTCAGATCTCTATTAG
TGATGACGAGGACGACGACGATTTTGAAATAAAGGAGGTAGACCCTCAGGCAGCCAAGAAGGGAGGAGGAAGAGGAGGAAGAAAGGCAGCTGCAGCAAATGGCAAAACCA
CCAAGGCCCCTGCTGCAGGAGGGAAGTTGGGGCAGAAACTGATAACTCAAATGCTAGAACCAGCAGAGAACTCCGGCATCTCACCAGAAAAGAAAGTGAGGAAGATAAGA
GCATCACCTTTCAACAAGAAAAGTGGCTCTTTATTGGGAAGAGCAATAGAGGAAGAAGAAGAGGACGGAATTGAAGATGAAGGGAAGGTGATGGGTTCGGCTTCTTCCGA
GACTAGTGAAGAAGTGGCCGGGTTTCAGCCGGCAATAGGAAGATCACGGAGAGCAAACAGAACACAGGTCAGGTATGTGCTTAGTGATTCAGATGATGAGGCAGTTTCTC
AGGATTCAGACTTTGATGAAGACGAAGCCAGCCTTGATGAAGATTGATTGAAGAAATCTCTTTGTATATAATATAGTTAACTTTTTCCTGTGAAGAAAAATTGAGATCGT
CCGGACTCCGTTTATCTTCTCATGGTGTAAGAGTATTTGTTTGCTAGAATTTAGGAAGTCAGTGTTGTTATTGGGGGATCGCATCTTATATGAAGATTTTGCATTTGATG
CAACTTTTCTATGTAACGTTGACTGACATCCAGAACAAAAGAAGAACAGAAGTCTACCCATGCTTTGGGTGGTATTTTAATATTCATTCCTATGGAAGAAAACGAAGAGT
TCTGTAAAGATGAAGCATAGTTGCACTAATATCAAATGATTC

Protein sequence

Show/hide protein sequence

MVVEKKRPLQNSNTANVDSNPAGPKKTIEEMYQKKSQLEHILLRPDTYVGSIEKHTQNLWVYENDKMVHRSISYVPGLYKIFDEILVNAADNKQRDPSMDSVKVNIDVEQ
NCISVFNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDTEKKTTGGRNGYGAKLTNIFSTEFVIETADGRRLKKYKQVFNDNMGKKSEPIITKCKEGDNWTRVTFKPD
LAKFNMTHLEDDVVALMKKRVLDLAGCLGKTVKVELNGQRVPVKSFQDYVDLYLKSASSFQAEPPKRYHIKPNERWEIVVTLSEGQFQQVSFVNGIATIKGGTHVEYITN
QIANYVMTAVNKKNKNANVKAHNVKNYLWVFINALIDNPSFDSQTKETLTKRANSFGSACELTPEFLKNVATKSGIMDSVLSWVNFKQSKDLKKTDGAKTEKISGIEKLE
DANCAGGKNSEKCTLILTEGDSAKALAMAGLGVVGRDFYGVFPLRGKLLNVREASSKQITENKEIQYIKQILGLQQGKEYNNAKALRYGHLMIMTDQDHDGSHIKGLLIN
FIHSFWPSLLRVPSFLVEFITPIVKATHKNGTVLSFYTMPEYESWKESLRGNASGWSIKYYKGLGTSTSKEGREYFEQLTKHKKDFIWQDDNDGEAIELAFSKKKIEDRK
NWLRQFEPGTHLDQTGKLIKYSDFVNKELILFSMADLQRSIPSMVDGLKPGQRKILFCSFKRNFIKEAKVSQFSGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLL
LPNGQFGTRNHGGKDHASSRYIYTKLSNVTRFLFPKDDDKLLNYLNEDGQSIEPTWYMPIIPTVLVNGSEGIGTGWSSYVPNYNPRDIIRNVRRMLDGETMLPMDPWYRG
FSGTIEKTATKEGGTTYTISGIIEEVSDTTLRIVELPVRRWTSDYKDFLDSVTRVASKHDKEKAAKDPFIEQADHHSDDKIVSIDVHLTEENMLLAIQEGLKKKFKLTTT
VSTSNMHLFDANGVIKKYDTPEQILEEFFPLRLEFYEKRKRILLDNLEMELLKLENKVRFILAVVNEEIKVSNRKKVDLFHELQAKGFTPFPKKTKSVEPEIAGASNETD
EAEESPEVVKGERISDYEYLLALPIGTLTIEKVQELCNDRDKLKGEVDDLRKATPKSLWLNDLDSLEKELDEVDRNDAQTMELRKQQRDKANNDLKPKISRNAPKAPRNS
KKTSNVETVTESMDTTYSSTTTEVANNPVVKPKGKAAPRKAPAKKKGKAAVPDEDDDDEVLELKDRLAAYKIESSPEPSEVSAMETEVQEVQAAKKKEPSKRAPAKKKTT
AKSAQISISDDEDDDDFEIKEVDPQAAKKGGGRGGRKAAAANGKTTKAPAAGGKLGQKLITQMLEPAENSGISPEKKVRKIRASPFNKKSGSLLGRAIEEEEEDGIEDEG
KVMGSASSETSEEVAGFQPAIGRSRRANRTQVRYVLSDSDDEAVSQDSDFDEDEASLDED

IVF0025580 (gene) of Melon (IVF77) v1 genome