CuGenDBv2

Gene ID	IVF0025733
Organism	Cucumis melo ssp. agrestis cv. IVF77 (Melon (IVF77) v1)
Description	DNA topoisomerase
Genome location	tig00000656:560179..572867
RNA-Seq Expression	IVF0025733
Synteny	IVF0025733
Gene Ontology terms	GO:0006265 - DNA topological change (biological process) GO:0005634 - nucleus (cellular component) GO:0003677 - DNA binding (molecular function) GO:0003917 - DNA topoisomerase type I activity (molecular function)
InterPro domains	IPR000380 - DNA topoisomerase, type IA IPR003601 - DNA topoisomerase, type IA, domain 2 IPR003602 - DNA topoisomerase, type IA, DNA-binding domain IPR006171 - TOPRIM domain IPR013497 - DNA topoisomerase, type IA, central IPR013824 - DNA topoisomerase, type IA, central region, subdomain 1 IPR013826 - DNA topoisomerase, type IA, central region, subdomain 3 IPR023405 - DNA topoisomerase, type IA, core domain IPR023406 - DNA topoisomerase, type IA, active site IPR034144 - DNA topoisomerase 3-like, TOPRIM domain

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAA0067650.1 DNA topoisomerase 3-beta [Cucumis melo var. makuwa]

0.0

96.17

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL
        MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW
        LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA                        GNTTPPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV
        EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIK+
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV

XP_004147675.1 DNA topoisomerase 3-beta isoform X1 [Cucumis sativus]

0.0

94.49

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Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL
        MVA TVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGH+FSIDFQAGFQDWK+T+PLDLFQASVIKTESNPKAHI QHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYI+Q GYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW
        LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMC ATEDMLGRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA                        GNTTPPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVV+SVLQQF+QKYSYFVKKID MDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV
        EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIK+
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV

XP_008439059.1 PREDICTED: DNA topoisomerase 3-beta [Cucumis melo]

0.0

96.17

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL
        MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW
        LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA                        GNTTPPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV
        EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIK+
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV

XP_022979706.1 DNA topoisomerase 3-beta isoform X1 [Cucurbita maxima]

0.0

90.96

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Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL
        MVAS+VLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHA+YKVTSVIGH+FSIDF A FQDWK T+PLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGN  RKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERG+LFDCDV  MFQKRV+EDGIAEVT+ISEKQE+KVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW
        LKVASSALG+GPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLH+LVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPM  ATEDM+GRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGS V VKGFTSIMPWLA                        GNT+PPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIE QIT VAKGQADH SVV++VLQQFKQKYSYFVKKID MDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV
        EAQFSPLA+SGRALSKCGKCLRYMKFISSQPQRLYCG CEEVYYLPQ+G IK+
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV

XP_038891105.1 DNA topoisomerase 3-beta isoform X1 [Benincasa hispida]

0.0

92.34

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL
        MVASTVLMVAEKPSIALSIASALSHGQMSTRKGST+VHEFDGRFLGHHA+YKVTSVIGH+FSIDF AGFQDWK+T+PLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGN  RKKVYRARFSSVTEKDILKALDNLV+PN+NEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTF PEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW
        LKVASSALGFGPQ+AMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTL+KN EWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMC ATEDMLGRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGE+FNCTGSRV VKGFTSIMPWLA                        GNTTPPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRL PTNLGITL+RGYQCIDPDLCLPDIRSFIE QITLVAKGQADHSSVV++VLQQFKQKY YFVKKID MDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV
        EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKG IK+
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV

TrEMBL top hits

e value

%identity

Alignment

A0A0A0L9C7 DNA topoisomerase

0.0e+00

94.49

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL
        MVA TVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGH+FSIDFQAGFQDWK+T+PLDLFQASVIKTESNPKAHI QHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYI+Q GYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW
        LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMC ATEDMLGRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA                        GNTTPPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVV+SVLQQF+QKYSYFVKKID MDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV
        EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIK+
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV

A0A1S3AYH7 DNA topoisomerase

0.0e+00

96.17

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL
        MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW
        LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA                        GNTTPPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV
        EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIK+
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV

A0A5A7VKD3 DNA topoisomerase

0.0e+00

96.17

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL
        MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW
        LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA                        GNTTPPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV
        EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIK+
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV

A0A6J1GWS0 DNA topoisomerase

0.0e+00

90.66

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL
        MVAS+VLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHA+YKVTSVIGH+FSIDF A FQDWK T+PLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGN  RKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERG+LFDCDV  MFQKRV+EDGIAEVT+ISEKQE+KVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW
        LKVASSALG+GPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLH+LVKNPEWGDYVR+LLSDGYSKPRSGTDVGDHPPITPM  ATEDM+GRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKY+RTKIQFSIAGEIFNCTGS V VKGFTSIMPWLA                        GNT+PPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIE QIT VAKGQADH SVV++VLQQFKQKYSYFVKKID MDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV
        EAQFSPLA+SGRALSKCGKCLRYMKFISSQPQRLYCG CEEVYYLPQ+G IK+
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV

A0A6J1IRJ0 DNA topoisomerase

0.0e+00

90.96

Show/hide

Query:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL
        MVAS+VLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHA+YKVTSVIGH+FSIDF A FQDWK T+PLDLFQASVIKTESNPKAHIRQHL
Subjt:  MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG
        SREARGCDCLVLWLDCDREGENICFEVIECTGFGGN  RKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGV+FTRFQTTFFQGKYG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYG

Query:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL
        NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERG+LFDCDV  MFQKRV+EDGIAEVT+ISEKQE+KVRPSGLNTVNL
Subjt:  NLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNL

Query:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW
        LKVASSALG+GPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLH+LVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPM  ATEDM+GRDAW
Subjt:  LKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAW

Query:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG
        RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGS V VKGFTSIMPWLA                        GNT+PPDYLSESELISLMEKHG
Subjt:  RLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHG

Query:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF
        IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIE QIT VAKGQADH SVV++VLQQFKQKYSYFVKKID MDALF
Subjt:  IGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALF

Query:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV
        EAQFSPLA+SGRALSKCGKCLRYMKFISSQPQRLYCG CEEVYYLPQ+G IK+
Subjt:  EAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV

SwissProt top hits

e value

%identity

Alignment

F4ISQ7 DNA topoisomerase 3-beta

4.3e-291

74.23

Show/hide

Query:  VLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHLSREAR
        VLMVAEKPSIALSIAS LSHGQMSTR+GSTEVHEFDG F G  A+Y+VTSVIGH+FS+DF   +Q+W T +P DLF A +IK ESNPKAHI +HLS EAR
Subjt:  VLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHLSREAR

Query:  GCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSR
        GC  +VLWLDCDREGENICFEVIE TGF    +++KVYRARFSSVTEKDI KA+DNLVEPNR+EALAVDARQEIDLKVGVAF+RFQT++FQGKY NLD R
Subjt:  GCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSR

Query:  LISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNLLKVAS
        +ISYGPCQTPTLGFCVQR++ I TFKPEKFW++ PYI ++GYEL L+WER +LFD +   +FQK V+E   A+V ++SEKQE K RP+GLNTVNLLKVAS
Subjt:  LISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNLLKVAS

Query:  SALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAWRLYQY
        SALGFGPQ AM LAERLYTQGFISYPRTESTAYPSSFDF  TL   V NP WG YV+ LLSDG+  P+SGTD GDHPPITPM +ATE M+G DAWRLYQY
Subjt:  SALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAWRLYQY

Query:  VCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHGIGTDA
        VCQHF+G++S +CKYIRTK++ SI GE F+CTG RVT KGFT+IMPW A                        GNT PPDYL+ESELISLMEKHGIGTDA
Subjt:  VCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHGIGTDA

Query:  SIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALFEAQFS
        SI VHINNIGERNYVQVQ+GR++VPT LGITLIRGYQCIDPDLCLPDIRSFIE QITLVAKGQADHS VV+ V+QQF++K+SYFV++I+ MDALFEAQFS
Subjt:  SIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALFEAQFS

Query:  PLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV
        PLADSGRALSKCGKCLRYMK I++ P RL+CG CEEVYYLPQKGT+K+
Subjt:  PLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV

O95985 DNA topoisomerase 3-beta-1

6.1e-205

53.65

Show/hide

Query:  TVLMVAEKPSIALSIASALSHGQMSTRK---GSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLF-QASVIKTESNPKAHIRQHL
        TVLMVAEKPS+A SIA  LS G +S+ K   G+  VHE+ G F G    +K+TSV GH+ ++DF   +  W   +P +LF QA   K E+NPK ++ + L
Subjt:  TVLMVAEKPSIALSIASALSHGQMSTRK---GSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLF-QASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIEC---TGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQG
          E RGCD +VLWLDCD+EGENICFEV++         +G  K V+RARFSS+T+ DI  A+  L EP+ NEAL+VDARQE+DL++G AFTRFQT +FQG
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIEC---TGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQG

Query:  KYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYI-MQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLN
        KYG+LDS LIS+GPCQTPTLGFCV+RH +I +FKPE +W +   +       L LDW+R ++FD ++  MF      +  A+V   S K++ K RP  LN
Subjt:  KYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYI-MQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLN

Query:  TVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLG
        TV +L+VASS+LG GPQ AMQ AERLYTQG+ISYPRTE+T YP +FD KG+L     +P W D V+ LL++G ++PR G D GDHPPITPM SATE  LG
Subjt:  TVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLG

Query:  RDAWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPW-------------------------LAGNTTPPDYLSESELISL
         DAWRLY+Y+ +HFI ++S DCKY+++ I F I  E+F C+G  V   GFT +MPW                         L   T PPDYL+E+ELI+L
Subjt:  RDAWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPW-------------------------LAGNTTPPDYLSESELISL

Query:  MEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDR
        MEKHGIGTDASIPVHINNI +RNYV V++GRRL PTNLGI L+ GY  ID +L LP IRS +E Q+ L+A+G+AD+  V+   L  FK+K+ YFV  I  
Subjt:  MEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDR

Query:  MDALFEAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV
        MD L E  FSPLA +G+ LS+CGKC R+MK+I ++P RL+C  C+E Y LPQ GTIK+
Subjt:  MDALFEAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV

O96651 DNA topoisomerase 3-beta

2.4e-193

50.46

Show/hide

Query:  TVLMVAEKPSIALSIASALSHGQMSTRKGS---TEVHEFDGRFLGH-HAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL
        +VLMVAEKPS+A S+A  LS+G+ + ++G+      HE+ G F      ++++TSV GH+ S+DF   +  W   +P+ LF  +  K E+NPK ++R+ L
Subjt:  TVLMVAEKPSIALSIASALSHGQMSTRKGS---TEVHEFDGRFLGH-HAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNG--TRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGK
        + EARGCD LVLWLDCD+EGENICFEV++      N   + +  YRA FS++TEKDI KA++ L  PN NEA +VDARQE+DL++G AFTRFQT FFQ +
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECTGFGGNG--TRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGK

Query:  YGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTV
        YG+LDS LISYGPCQTPTLGFCV+RH  I TFKPE FW +   ++    E+ L+W RG++F  D+  M   RV E   A V  ++ K+  K +P  LNTV
Subjt:  YGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTV

Query:  NLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRD
         L+++ SS LG GP  AMQ+AERLYTQG+ISYPRTE+  YP++FD    LH L  + ++G+  R +L D    PR G D GDHPPITPM         RD
Subjt:  NLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRD

Query:  AWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA-------------------------GNTTPPDYLSESELISLME
         WR+Y+++C+HF+G++S D KY  T  + S+  E F+CT S +   GFT +M W A                           T PPDYL+ESELI+LME
Subjt:  AWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA-------------------------GNTTPPDYLSESELISLME

Query:  KHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMD
        +HGIGTDASIPVHINNI +RNYV ++ GR+L+PT LGI L+ GYQ IDP+L LP +R+ +E  +TL+A+G A+   V+   ++ FK K+ YFVK ID MD
Subjt:  KHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMD

Query:  ALFEAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV
        ALFE  FSPLA+SG+A S+CGKC RYMK+I ++P RL+C  C+E Y LP  G +KV
Subjt:  ALFEAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV

Q0J0S6 DNA topoisomerase 3-beta

8.1e-282

71.63

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Query:  VASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHLS
        +A TVLMVAEKPSIALSIASALS G+MSTRKGST+VHEFDG F G HA++KVTSVIGH+ S+DF   +Q+W+ T+P+DLF A V+++E NPKAHIR+HL+
Subjt:  VASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHLS

Query:  REARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGN
        +EARGC  LVLWLDCDREGENIC+EVI+CTG   +   ++++RA+FSSVTEKDI+ A++NLV P+++EALAVDARQEIDLKVGVAFTRFQT +FQGKYGN
Subjt:  REARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGN

Query:  LDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNLL
        LDSR+ISYGPCQTPTLGFCVQR+ QITTFKPEKFWS+  Y++++G E+ L+W+R KLFD DVT MFQK V  DGI +VT+IS K+E K RP GLNTVNLL
Subjt:  LDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNLL

Query:  KVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAWR
        KVASSALG GPQ AM LAERLYTQGFISYPRTESTAYPSSFDF+  L  L  NP W + VR LL  G+ KP+ G D GDHPPITPM  ATE+ LG DAWR
Subjt:  KVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAWR

Query:  LYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHGI
        LYQY+CQHFIG++S DC+Y RT I+F+  GE F+C G+RVT KGFTSIMPWLA                        G+TTPPDYLSESELISLMEK+GI
Subjt:  LYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHGI

Query:  GTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALFE
        GTDASIPVH+NNI ERNYVQV +GRRLVPT LG TLIRGYQCID DLCLPDIR FIE QITL+AKG+ADH  VV+ VLQQF +KYSYFVKKI+ MDALFE
Subjt:  GTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALFE

Query:  AQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV
        AQFSPLADSGR LSKCGKC RYMK+IS+QP RLYC  CEEVYYLPQ G+IK+
Subjt:  AQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV

Q9Z321 DNA topoisomerase 3-beta-1

2.8e-205

54.17

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Query:  TVLMVAEKPSIALSIASALSHGQMSTRK---GSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLF-QASVIKTESNPKAHIRQHL
        TVLMVAEKPS+A SIA  LS G MS+ K   G+  VH++ G F G   ++K+TSV GH+ ++DF   +  W   +P +LF QA   K E+NPK ++ + L
Subjt:  TVLMVAEKPSIALSIASALSHGQMSTRK---GSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLF-QASVIKTESNPKAHIRQHL

Query:  SREARGCDCLVLWLDCDREGENICFEVIECT----GFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQ
          E RGCD +VLWLDCD+EGENICFEV++          NG  K V+RARFSS+T+ DI  A+  L EP+ NEAL+VDARQE+DL++G AFTRFQT +FQ
Subjt:  SREARGCDCLVLWLDCDREGENICFEVIECT----GFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQ

Query:  GKYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYE-LNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGL
        GKYG+LDS LIS+GPCQTPTLGFCV+RH +I +FKPE +W +   +  +  E L LDW+R ++FD ++  MF      +  A V   S K++ K RP  L
Subjt:  GKYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYE-LNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGL

Query:  NTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDML
        NTV +L+VASSALG GPQ AMQ+AERLYTQG+ISYPRTE+T YP +FD KG+L     +P W D V+ LL++G ++PR G D GDHPPITPM SATE  L
Subjt:  NTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDML

Query:  GRDAWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPW-------------------------LAGNTTPPDYLSESELIS
        G DAWRLY+Y+ +HFI ++S DCKY+++ I F I  E F C G  V   GFT IMPW                         L   T+PPDYL+E+ELI+
Subjt:  GRDAWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPW-------------------------LAGNTTPPDYLSESELIS

Query:  LMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKID
        LMEKHGIGTDASIPVHINNI +RNYV V++GRRL PTNLGI L+ GY  ID +L LP IRS +E Q+ L+A+G+AD+  V+   L  FK+K+ YFV  I 
Subjt:  LMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKID

Query:  RMDALFEAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV
         MD L E  FSPLA +G+ LS+CGKC R+MK+I ++P RL+C  C+E Y LPQ GTIK+
Subjt:  RMDALFEAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV

Arabidopsis top hits

e value

%identity

Alignment

AT2G32000.1 DNA topoisomerase, type IA, core

3.0e-292

74.23

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Query:  VLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHLSREAR
        VLMVAEKPSIALSIAS LSHGQMSTR+GSTEVHEFDG F G  A+Y+VTSVIGH+FS+DF   +Q+W T +P DLF A +IK ESNPKAHI +HLS EAR
Subjt:  VLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHLSREAR

Query:  GCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSR
        GC  +VLWLDCDREGENICFEVIE TGF    +++KVYRARFSSVTEKDI KA+DNLVEPNR+EALAVDARQEIDLKVGVAF+RFQT++FQGKY NLD R
Subjt:  GCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSR

Query:  LISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNLLKVAS
        +ISYGPCQTPTLGFCVQR++ I TFKPEKFW++ PYI ++GYEL L+WER +LFD +   +FQK V+E   A+V ++SEKQE K RP+GLNTVNLLKVAS
Subjt:  LISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNLLKVAS

Query:  SALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAWRLYQY
        SALGFGPQ AM LAERLYTQGFISYPRTESTAYPSSFDF  TL   V NP WG YV+ LLSDG+  P+SGTD GDHPPITPM +ATE M+G DAWRLYQY
Subjt:  SALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAWRLYQY

Query:  VCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHGIGTDA
        VCQHF+G++S +CKYIRTK++ SI GE F+CTG RVT KGFT+IMPW A                        GNT PPDYL+ESELISLMEKHGIGTDA
Subjt:  VCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA------------------------GNTTPPDYLSESELISLMEKHGIGTDA

Query:  SIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALFEAQFS
        SI VHINNIGERNYVQVQ+GR++VPT LGITLIRGYQCIDPDLCLPDIRSFIE QITLVAKGQADHS VV+ V+QQF++K+SYFV++I+ MDALFEAQFS
Subjt:  SIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALFEAQFS

Query:  PLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV
        PLADSGRALSKCGKCLRYMK I++ P RL+CG CEEVYYLPQKGT+K+
Subjt:  PLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV

AT2G32000.2 DNA topoisomerase, type IA, core

9.2e-265

72.74

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Query:  HIFSI---DFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDI
        H+ S+   DF   +Q+W T +P DLF A +IK ESNPKAHI +HLS EARGC  +VLWLDCDREGENICFEVIE TGF    +++KVYRARFSSVTEKDI
Subjt:  HIFSI---DFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHLSREARGCDCLVLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDI

Query:  LKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWER
         KA+DNLVEPNR+EALAVDARQEIDLKVGVAF+RFQT++FQGKY NLD R+ISYGPCQTPTLGFCVQR++ I TFKPEKFW++ PYI ++GYEL L+WER
Subjt:  LKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWER

Query:  GKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNP
         +LFD +   +FQK V+E   A+V ++SEKQE K RP+GLNTVNLLKVASSALGFGPQ AM LAERLYTQGFISYPRTESTAYPSSFDF  TL   V NP
Subjt:  GKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNP

Query:  EWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA-
         WG YV+ LLSDG+  P+SGTD GDHPPITPM +ATE M+G DAWRLYQYVCQHF+G++S +CKYIRTK++ SI GE F+CTG RVT KGFT+IMPW A 
Subjt:  EWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFTSIMPWLA-

Query:  -----------------------GNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRS
                               GNT PPDYL+ESELISLMEKHGIGTDASI VHINNIGERNYVQVQ+GR++VPT LGITLIRGYQCIDPDLCLPDIRS
Subjt:  -----------------------GNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRS

Query:  FIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALFEAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV
        FIE QITLVAKGQADHS VV+ V+QQF++K+SYFV++I+ MDALFEAQFSPLADSGRALSKCGKCLRYMK I++ P RL+CG CEEVYYLPQKGT+K+
Subjt:  FIEHQITLVAKGQADHSSVVESVLQQFKQKYSYFVKKIDRMDALFEAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKV

AT5G63920.1 topoisomerase 3alpha

1.2e-107

36.72

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Query:  TVLMVAEKPSIALSIASALSHGQMSTRKGST---EVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHLS
        TVL VAEKPS+A S+A  LS G   TR+G +   ++ EFD    G      +TSVIGH+  ++F   ++ W + +P DL+QA V+K     K  I++ L 
Subjt:  TVLMVAEKPSIALSIASALSHGQMSTRKGST---EVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHLS

Query:  REARGCDCLVLWLDCDREGENICFEVIE-CTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKY-
         EAR  D LVLWLDCDREGENI FEV++ C     N     + RA FS++ ++DI +A+ NL +PN+  A AVDARQEIDL++G +FTRFQT   + ++ 
Subjt:  REARGCDCLVLWLDCDREGENICFEVIE-CTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKY-

Query:  ----GNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSV-CPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQEN-KVRPS
            G   SR+ISYGPCQ PTLGF V+R+ +I   +PE+FW++ C +  + G     +W RG LFD     +  +  +E+  A V  +   +E  K  P 
Subjt:  ----GNLDSRLISYGPCQTPTLGFCVQRHLQITTFKPEKFWSV-CPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQEN-KVRPS

Query:  GLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSD----GYSKPRSGTDVGDHPPITP-MC
         LNT+ L K AS       +  M++AE LY  GFISYPRTE+ ++ S  D +  +    ++P WG Y + LL        +    G D   HPPI P   
Subjt:  GLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISYPRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSD----GYSKPRSGTDVGDHPPITP-MC

Query:  SATEDMLGRDAWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFT----------SIMPWL--------------AGNTTPPDYLS
        S+ E    RD   +Y+ V +H++  +S       T ++  IAGE F+ +G  +  K +           S++P                A  T PP  L 
Subjt:  SATEDMLGRDAWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSRVTVKGFT----------SIMPWL--------------AGNTTPPDYLS

Query:  ESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKY-S
        E++L+S M+K GIGTDA++  HI  + +R Y    A  R  PTNLG  L+ GY  +  +L  P++R+ +EH +  V+ G+   + V+E+ LQQ K  +  
Subjt:  ESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSVVESVLQQFKQKY-S

Query:  YFVKK---IDRMDALFE----AQFSPLADSGRALSKCGKC
          VKK   ++ M   FE       S    +G  + +C  C
Subjt:  YFVKK---IDRMDALFE----AQFSPLADSGRALSKCGKC

Sequences

Show/hide sequences

CDS sequence

Show/hide CDS sequence

ATGGTTGCTTCAACGGTTCTTATGGTTGCAGAGAAGCCTAGCATTGCGCTTTCAATTGCTTCTGCACTCTCCCATGGCCAAATGTCTACAAGAAAGGGTAGCACAGAGGT
ACATGAATTTGATGGGAGATTTCTTGGGCATCATGCTTATTATAAAGTGACATCGGTTATTGGACATATTTTCAGTATAGATTTCCAAGCTGGATTTCAAGATTGGAAGA
CCACCAATCCTTTGGATCTTTTTCAAGCTTCAGTAATTAAGACAGAATCAAACCCAAAGGCGCACATACGTCAACATTTAAGTCGAGAAGCGCGTGGTTGTGATTGTTTG
GTTTTATGGTTGGATTGTGATCGTGAAGGAGAAAATATTTGTTTTGAAGTTATTGAGTGCACTGGATTTGGTGGCAATGGAACGAGGAAAAAAGTGTATCGTGCAAGGTT
TTCTTCTGTTACTGAGAAAGATATTCTGAAGGCTTTGGATAACCTTGTTGAACCTAATAGAAATGAGGCACTTGCTGTTGATGCTCGACAAGAGATAGATTTGAAAGTTG
GAGTAGCCTTTACGCGATTTCAGACTACCTTTTTTCAGGGAAAATATGGAAACCTCGATTCCAGACTCATTTCCTATGGACCATGCCAAACTCCCACGCTTGGGTTTTGT
GTACAGCGTCATTTGCAAATAACCACCTTTAAACCAGAAAAATTTTGGTCTGTATGCCCTTATATTATGCAAAACGGCTATGAGCTTAATTTGGACTGGGAACGTGGCAA
GTTATTCGACTGTGATGTTACTGCAATGTTTCAAAAGCGAGTAATAGAAGATGGAATTGCAGAAGTAACAGAAATATCAGAGAAGCAAGAAAACAAAGTTCGGCCTTCTG
GACTAAATACAGTTAACCTTCTGAAGGTTGCTTCAAGTGCACTAGGATTTGGACCTCAAATGGCAATGCAACTAGCCGAAAGATTGTATACACAAGGATTCATCAGCTAT
CCACGTACAGAAAGTACGGCTTATCCTTCTTCGTTTGACTTCAAAGGCACTCTACATACCCTAGTGAAAAATCCAGAATGGGGTGATTATGTACGGATGCTTCTGTCTGA
TGGATACAGTAAACCACGATCAGGAACTGACGTGGGTGATCATCCTCCCATTACTCCAATGTGTTCAGCAACAGAAGATATGTTAGGGAGAGATGCTTGGAGATTGTACC
AATATGTGTGTCAACATTTCATTGGATCTCTGTCTTCTGACTGCAAGTATATTAGGACGAAGATACAGTTTTCAATCGCTGGAGAAATATTCAATTGTACTGGGTCACGT
GTTACAGTAAAAGGATTCACCTCCATTATGCCATGGTTGGCAGGGAATACCACGCCTCCGGATTATTTAAGTGAAAGTGAGTTGATTTCTCTCATGGAGAAGCATGGAAT
AGGCACGGATGCATCAATACCCGTACACATTAACAACATAGGCGAGCGCAACTATGTTCAGGTTCAAGCTGGGAGGAGGTTGGTTCCAACTAACTTGGGCATCACCTTAA
TTAGAGGATATCAATGTATTGATCCAGATCTCTGTTTACCAGATATTCGAAGTTTCATCGAGCATCAGATCACTCTTGTTGCGAAAGGTCAAGCAGATCATTCTAGTGTT
GTGGAGAGTGTATTGCAACAGTTCAAGCAAAAGTATAGCTACTTCGTTAAGAAGATTGATCGTATGGATGCTCTATTTGAAGCACAATTTTCTCCCCTTGCCGATTCAGG
ACGTGCTTTGAGCAAATGTGGAAAGTGCCTACGGTATATGAAGTTTATTTCTTCCCAACCACAGCGTCTGTACTGTGGTATATGTGAGGAGGTTTATTATCTTCCTCAAA
AGGGAACAATAAAGGTAAATATCCCACAAAATAGTTCCAATTCCTTCCATTGA

mRNA sequence

Show/hide mRNA sequence

Protein sequence

Show/hide protein sequence

MVASTVLMVAEKPSIALSIASALSHGQMSTRKGSTEVHEFDGRFLGHHAYYKVTSVIGHIFSIDFQAGFQDWKTTNPLDLFQASVIKTESNPKAHIRQHLSREARGCDCL
VLWLDCDREGENICFEVIECTGFGGNGTRKKVYRARFSSVTEKDILKALDNLVEPNRNEALAVDARQEIDLKVGVAFTRFQTTFFQGKYGNLDSRLISYGPCQTPTLGFC
VQRHLQITTFKPEKFWSVCPYIMQNGYELNLDWERGKLFDCDVTAMFQKRVIEDGIAEVTEISEKQENKVRPSGLNTVNLLKVASSALGFGPQMAMQLAERLYTQGFISY
PRTESTAYPSSFDFKGTLHTLVKNPEWGDYVRMLLSDGYSKPRSGTDVGDHPPITPMCSATEDMLGRDAWRLYQYVCQHFIGSLSSDCKYIRTKIQFSIAGEIFNCTGSR
VTVKGFTSIMPWLAGNTTPPDYLSESELISLMEKHGIGTDASIPVHINNIGERNYVQVQAGRRLVPTNLGITLIRGYQCIDPDLCLPDIRSFIEHQITLVAKGQADHSSV
VESVLQQFKQKYSYFVKKIDRMDALFEAQFSPLADSGRALSKCGKCLRYMKFISSQPQRLYCGICEEVYYLPQKGTIKVNIPQNSSNSFH

IVF0025733 (gene) of Melon (IVF77) v1 genome