CuGenDBv2

Gene ID	Lag0002399
Organism	Luffa acutangula AG-4 (Sponge gourd (AG-4) v1)
Description	Pre-mRNA-splicing factor 18
Genome location	chr4:42454207..42455643
RNA-Seq Expression	Lag0002399
Synteny	Lag0002399
Gene Ontology terms	GO:0000350 - generation of catalytic spliceosome for second transesterification step (biological process) GO:0071048 - nuclear retention of unspliced pre-mRNA at the site of transcription (biological process) GO:0005682 - U5 snRNP (cellular component) GO:0046540 - U4/U6 x U5 tri-snRNP complex (cellular component) GO:0071021 - U2-type post-spliceosomal complex (cellular component)
InterPro domains	IPR004098 - Prp18 IPR039979 - Pre-mRNA-splicing factor 18

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

KAG6575910.1 Pre-mRNA-splicing factor 18, partial [Cucurbita argyrosperma subsp. sororia]

6.8e-70

97.84

Show/hide

Query:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
        K+LPDDIRQAL+VVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
Subjt:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF

Query:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS
        NSLANGSDLQSLLAEERVSGGGK GSDERLRIMPAPEDS
Subjt:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS

XP_004146980.1 pre-mRNA-splicing factor 18 [Cucumis sativus]

1.2e-69

97.84

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Query:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
        K+LPDDIRQAL+VVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
Subjt:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF

Query:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS
        NSLANGSDLQSLLAEERVSGGGK GSDERLRIMPAPEDS
Subjt:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS

XP_022954136.1 pre-mRNA-splicing factor 18 [Cucurbita moschata]

6.8e-70

97.84

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Query:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
        K+LPDDIRQAL+VVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
Subjt:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF

Query:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS
        NSLANGSDLQSLLAEERVSGGGK GSDERLRIMPAPEDS
Subjt:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS

XP_022992522.1 pre-mRNA-splicing factor 18-like [Cucurbita maxima]

6.8e-70

97.84

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Query:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
        K+LPDDIRQAL+VVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
Subjt:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF

Query:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS
        NSLANGSDLQSLLAEERVSGGGK GSDERLRIMPAPEDS
Subjt:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS

XP_023549183.1 pre-mRNA-splicing factor 18-like [Cucurbita pepo subsp. pepo]

6.8e-70

97.84

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Query:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
        K+LPDDIRQAL+VVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
Subjt:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF

Query:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS
        NSLANGSDLQSLLAEERVSGGGK GSDERLRIMPAPEDS
Subjt:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS

TrEMBL top hits

e value

%identity

Alignment

A0A0A0K7C9 Pre-mRNA-splicing factor 18

5.6e-70

97.84

Show/hide

Query:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
        K+LPDDIRQAL+VVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
Subjt:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF

Query:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS
        NSLANGSDLQSLLAEERVSGGGK GSDERLRIMPAPEDS
Subjt:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS

A0A1S3BS26 Pre-mRNA-splicing factor 18

5.6e-70

97.84

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Query:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
        K+LPDDIRQAL+VVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
Subjt:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF

Query:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS
        NSLANGSDLQSLLAEERVSGGGK GSDERLRIMPAPEDS
Subjt:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS

A0A5D3DRE9 Pre-mRNA-splicing factor 18

5.6e-70

97.84

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Query:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
        K+LPDDIRQAL+VVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
Subjt:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF

Query:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS
        NSLANGSDLQSLLAEERVSGGGK GSDERLRIMPAPEDS
Subjt:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS

A0A6J1GQ96 Pre-mRNA-splicing factor 18

3.3e-70

97.84

Show/hide

Query:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
        K+LPDDIRQAL+VVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
Subjt:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF

Query:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS
        NSLANGSDLQSLLAEERVSGGGK GSDERLRIMPAPEDS
Subjt:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS

A0A6J1JZG6 Pre-mRNA-splicing factor 18

3.3e-70

97.84

Show/hide

Query:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
        K+LPDDIRQAL+VVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
Subjt:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF

Query:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS
        NSLANGSDLQSLLAEERVSGGGK GSDERLRIMPAPEDS
Subjt:  NSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS

SwissProt top hits

e value

%identity

Alignment

Q2HJ41 Pre-mRNA-splicing factor 18

1.3e-31

58.42

Show/hide

Query:  LPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEFNS
        LP DI++++  +++  ++R+Y+ A D Y++MAIGNAPWPIGVTMVGIH R+ REKI++  VAH++NDET RKY+Q +KRLMT CQ+ +PT PSK VE+N+
Subjt:  LPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEFNS

Query:  L
        L
Subjt:  L

Q5RE03 Pre-mRNA-splicing factor 18

1.3e-31

58.42

Show/hide

Query:  LPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEFNS
        LP DI++++  +++  ++R+Y+ A D Y++MAIGNAPWPIGVTMVGIH R+ REKI++  VAH++NDET RKY+Q +KRLMT CQ+ +PT PSK VE+N+
Subjt:  LPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEFNS

Query:  L
        L
Subjt:  L

Q6GMH0 Pre-mRNA-splicing factor 18

7.6e-32

58.25

Show/hide

Query:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
        K LP DI++++  +++  ++R+Y+ A D Y++MAIGNAPWPIGVTMVGIH R+ REKI++  VAH++NDET RKY+Q +KRLMT CQ+ +PT PSK VE+
Subjt:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF

Query:  NSL
        N+L
Subjt:  NSL

Q8BM39 Pre-mRNA-splicing factor 18

1.3e-31

58.42

Show/hide

Query:  LPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEFNS
        LP DI++++  +++  ++R+Y+ A D Y++MAIGNAPWPIGVTMVGIH R+ REKI++  VAH++NDET RKY+Q +KRLMT CQ+ +PT PSK VE+N+
Subjt:  LPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEFNS

Query:  L
        L
Subjt:  L

Q99633 Pre-mRNA-splicing factor 18

1.3e-31

58.42

Show/hide

Query:  LPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEFNS
        LP DI++++  +++  ++R+Y+ A D Y++MAIGNAPWPIGVTMVGIH R+ REKI++  VAH++NDET RKY+Q +KRLMT CQ+ +PT PSK VE+N+
Subjt:  LPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEFNS

Query:  L
        L
Subjt:  L

Arabidopsis top hits

e value

%identity

Alignment

AT1G03140.1 splicing factor Prp18 family protein

1.0e-60

83.57

Show/hide

Query:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF
        K LP DIRQAL+V+V  C+KRDYLAAMD YIK+AIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQS+KRLMTFCQRRYPTMPSKAVEF
Subjt:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEF

Query:  NSLANGSDLQSLLAEERVSGGGKPG-SDERLRIMPAPEDS
        NSLANGSDLQSLLAEER  GG +   S+ERLR+MP+  +S
Subjt:  NSLANGSDLQSLLAEERVSGGGKPG-SDERLRIMPAPEDS

AT1G54590.1 INVOLVED IN: RNA splicing

1.6e-48

72.26

Show/hide

Query:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYT-NSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVE
        K LP DIRQ L+V+V C +KRDYL A  Q+IK+AIGNAPWPIGVTMVGIHERSAREKI T +SVAHIMN+ETTRKYLQS+KRLMTFCQRRY  +PSK++E
Subjt:  KILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIGVTMVGIHERSAREKIYT-NSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVE

Query:  FNSLANGSDLQSLLAEERVSGGGKPG-SDERLRIMPA
        FNSLANGS+L SLLAEER     +   S+ERL +MP+
Subjt:  FNSLANGSDLQSLLAEERVSGGGKPG-SDERLRIMPA

Sequences

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CDS sequence

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ATGAGAGAGAGCATCTCCTCTCGGAAGCGCTTGAAAGTGGATCATTACCCATCCAAAAGTCATTCCCATAGCTTTTATTCTTGTCATTCCAATCGAGACTTTGATCCTAT
TGGAGATGAATTCGTTTTAATTGATAATAGAGCTGAATGCTTAACTTTTGGCCTAATAGCCTTCTCAGTTAGACCCTTTGCGTCCTGTGTGAAGATTCTTCCCGACGATA
TTCGGCAAGCATTGGTGGTGGTCGTCGAATGCTGCATGAAGCGCGACTATCTAGCTGCCATGGATCAGTACATTAAGATGGCTATTGGAAATGCCCCCTGGCCTATTGGT
GTCACTATGGTTGGTATTCACGAACGTTCAGCTCGTGAGAAGATTTACACCAACAGTGTGGCCCATATCATGAATGATGAAACAACAAGGAAGTACTTGCAATCGATCAA
GAGATTGATGACATTTTGTCAACGGCGCTATCCAACAATGCCATCCAAGGCAGTAGAATTTAACAGCTTGGCAAATGGCAGCGACCTGCAGTCCCTGCTAGCAGAAGAGA
GAGTTTCTGGAGGAGGTAAGCCGGGTTCCGATGAAAGGCTGCGAATCATGCCCGCCCCAGAAGATAGCTAG

mRNA sequence

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Protein sequence

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MRESISSRKRLKVDHYPSKSHSHSFYSCHSNRDFDPIGDEFVLIDNRAECLTFGLIAFSVRPFASCVKILPDDIRQALVVVVECCMKRDYLAAMDQYIKMAIGNAPWPIG
VTMVGIHERSAREKIYTNSVAHIMNDETTRKYLQSIKRLMTFCQRRYPTMPSKAVEFNSLANGSDLQSLLAEERVSGGGKPGSDERLRIMPAPEDS

Lag0002399 (gene) of Sponge gourd (AG-4) v1 genome