CuGenDBv2

Gene ID	Lag0015429
Organism	Luffa acutangula AG-4 (Sponge gourd (AG-4) v1)
Description	tyrosyl-DNA phosphodiesterase 1
Genome location	chr12:12889761..12896536
RNA-Seq Expression	Lag0015429
Synteny	Lag0015429
Gene Ontology terms	GO:0006281 - DNA repair (biological process) GO:0005634 - nucleus (cellular component) GO:0008081 - phosphoric diester hydrolase activity (molecular function)
InterPro domains	IPR010347 - Tyrosyl-DNA phosphodiesterase I

Homology

Show/hide homology

GenBank top hits

e value

%identity

Alignment

XP_022978029.1 tyrosyl-DNA phosphodiesterase 1 isoform X1 [Cucurbita maxima]

4.0e-33

45.97

Show/hide

Query:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC
        MGGPLEN Q+GI QSK D+SVE IRNF+V DD+ PMTFRL S KGLPPWANTSCVRI+DVIQGDILF VLSNYMVD+D  LIP                C
Subjt:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC

Query:  FTFVQ---FLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFED
         T  +    L +H         + RKKPANW+                                                        QNSS RGCAFED
Subjt:  FTFVQ---FLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFED

Query:  ELVDYLSALKF
        +LVDYLSALK+
Subjt:  ELVDYLSALKF

XP_022978031.1 tyrosyl-DNA phosphodiesterase 1 isoform X2 [Cucurbita maxima]

4.0e-33

45.97

Show/hide

Query:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC
        MGGPLEN Q+GI QSK D+SVE IRNF+V DD+ PMTFRL S KGLPPWANTSCVRI+DVIQGDILF VLSNYMVD+D  LIP                C
Subjt:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC

Query:  FTFVQ---FLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFED
         T  +    L +H         + RKKPANW+                                                        QNSS RGCAFED
Subjt:  FTFVQ---FLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFED

Query:  ELVDYLSALKF
        +LVDYLSALK+
Subjt:  ELVDYLSALKF

XP_022978032.1 tyrosyl-DNA phosphodiesterase 1 isoform X3 [Cucurbita maxima]

4.0e-33

45.97

Show/hide

Query:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC
        MGGPLEN Q+GI QSK D+SVE IRNF+V DD+ PMTFRL S KGLPPWANTSCVRI+DVIQGDILF VLSNYMVD+D  LIP                C
Subjt:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC

Query:  FTFVQ---FLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFED
         T  +    L +H         + RKKPANW+                                                        QNSS RGCAFED
Subjt:  FTFVQ---FLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFED

Query:  ELVDYLSALKF
        +LVDYLSALK+
Subjt:  ELVDYLSALKF

XP_023544483.1 tyrosyl-DNA phosphodiesterase 1 isoform X1 [Cucurbita pepo subsp. pepo]

5.3e-33

46.45

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Query:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC
        MGGPLEN Q+GI QSK D+SVE IRNF+V DD+ PMTFRL S KGLPPWANTSCVRI+DVIQGDILF VLSNYMVDID  LIP                C
Subjt:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC

Query:  FTFVQ---FLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFED
         T  +    L  H         + RKKPANW+                                                        QNSS RGCAFED
Subjt:  FTFVQ---FLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFED

Query:  ELVDYLSALKF
        +LVDYLSALK+
Subjt:  ELVDYLSALKF

XP_023544485.1 tyrosyl-DNA phosphodiesterase 1 isoform X3 [Cucurbita pepo subsp. pepo]

5.3e-33

46.45

Show/hide

Query:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC
        MGGPLEN Q+GI QSK D+SVE IRNF+V DD+ PMTFRL S KGLPPWANTSCVRI+DVIQGDILF VLSNYMVDID  LIP                C
Subjt:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC

Query:  FTFVQ---FLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFED
         T  +    L  H         + RKKPANW+                                                        QNSS RGCAFED
Subjt:  FTFVQ---FLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFED

Query:  ELVDYLSALKF
        +LVDYLSALK+
Subjt:  ELVDYLSALKF

TrEMBL top hits

e value

%identity

Alignment

A0A1S3AZK7 tyrosyl-DNA phosphodiesterase 1 isoform X1

7.4e-33

46.63

Show/hide

Query:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC
        MG PLEN QSG  QSK D+SVE IRNF++ DDR PMTFRL S KGLPPWANTSCVRITD+IQGDILF VLSNYMVDID  LIP        A   L+   
Subjt:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC

Query:  FTFVQFLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFEDELV
            Q L +H         + RKKPANW+                                                        QNSS RGCAFED+LV
Subjt:  FTFVQFLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFEDELV

Query:  DYLSALKF
        +YLSALK+
Subjt:  DYLSALKF

A0A1S3B014 tyrosyl-DNA phosphodiesterase 1 isoform X2

7.4e-33

46.63

Show/hide

Query:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC
        MG PLEN QSG  QSK D+SVE IRNF++ DDR PMTFRL S KGLPPWANTSCVRITD+IQGDILF VLSNYMVDID  LIP        A   L+   
Subjt:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC

Query:  FTFVQFLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFEDELV
            Q L +H         + RKKPANW+                                                        QNSS RGCAFED+LV
Subjt:  FTFVQFLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFEDELV

Query:  DYLSALKF
        +YLSALK+
Subjt:  DYLSALKF

A0A6J1IK17 tyrosyl-DNA phosphodiesterase 1 isoform X3

2.0e-33

45.97

Show/hide

Query:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC
        MGGPLEN Q+GI QSK D+SVE IRNF+V DD+ PMTFRL S KGLPPWANTSCVRI+DVIQGDILF VLSNYMVD+D  LIP                C
Subjt:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC

Query:  FTFVQ---FLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFED
         T  +    L +H         + RKKPANW+                                                        QNSS RGCAFED
Subjt:  FTFVQ---FLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFED

Query:  ELVDYLSALKF
        +LVDYLSALK+
Subjt:  ELVDYLSALKF

A0A6J1ILM7 tyrosyl-DNA phosphodiesterase 1 isoform X2

2.0e-33

45.97

Show/hide

Query:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC
        MGGPLEN Q+GI QSK D+SVE IRNF+V DD+ PMTFRL S KGLPPWANTSCVRI+DVIQGDILF VLSNYMVD+D  LIP                C
Subjt:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC

Query:  FTFVQ---FLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFED
         T  +    L +H         + RKKPANW+                                                        QNSS RGCAFED
Subjt:  FTFVQ---FLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFED

Query:  ELVDYLSALKF
        +LVDYLSALK+
Subjt:  ELVDYLSALKF

A0A6J1INX7 tyrosyl-DNA phosphodiesterase 1 isoform X1

2.0e-33

45.97

Show/hide

Query:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC
        MGGPLEN Q+GI QSK D+SVE IRNF+V DD+ PMTFRL S KGLPPWANTSCVRI+DVIQGDILF VLSNYMVD+D  LIP                C
Subjt:  MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNC

Query:  FTFVQ---FLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFED
         T  +    L +H         + RKKPANW+                                                        QNSS RGCAFED
Subjt:  FTFVQ---FLAVH------RSCLSRKKPANWVY-------------------------------------------------------QNSSARGCAFED

Query:  ELVDYLSALKF
        +LVDYLSALK+
Subjt:  ELVDYLSALKF

SwissProt top hits

e value

%identity

Alignment

Q8H1D9 Tyrosyl-DNA phosphodiesterase 1

2.7e-16

30.53

Show/hide

Query:  LENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNCFTFV
        L N ++     K +D VE IR F   +++ P TFRL S   LP WANTSCV I DVI+GD++  +LSNYMVDID          L  A   L+       
Subjt:  LENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNCFTFV

Query:  QFLAVH------RSCLSRKKPANWV---------------------------------------YQNSS-----------------ARGCAFEDELVDYL
        Q + +H      +  + RKKPANW+                                       + N S                  +GC FE +L+DYL
Subjt:  QFLAVH------RSCLSRKKPANWV---------------------------------------YQNSS-----------------ARGCAFEDELVDYL

Query:  SALKFNTKNPFTQEQLDEGSTKITEA
        + LK+     FT      G+ KI  A
Subjt:  SALKFNTKNPFTQEQLDEGSTKITEA

Arabidopsis top hits

e value

%identity

Alignment

AT5G15170.1 tyrosyl-DNA phosphodiesterase-related

1.9e-17

30.53

Show/hide

Query:  LENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNCFTFV
        L N ++     K +D VE IR F   +++ P TFRL S   LP WANTSCV I DVI+GD++  +LSNYMVDID          L  A   L+       
Subjt:  LENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNCFTFV

Query:  QFLAVH------RSCLSRKKPANWV---------------------------------------YQNSS-----------------ARGCAFEDELVDYL
        Q + +H      +  + RKKPANW+                                       + N S                  +GC FE +L+DYL
Subjt:  QFLAVH------RSCLSRKKPANWV---------------------------------------YQNSS-----------------ARGCAFEDELVDYL

Query:  SALKFNTKNPFTQEQLDEGSTKITEA
        + LK+     FT      G+ KI  A
Subjt:  SALKFNTKNPFTQEQLDEGSTKITEA

Sequences

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CDS sequence

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ATGGGAGGCCCTTTGGAGAATTCACAATCTGGGATCTTGCAGTCTAAGATGGATGATAGTGTGGAGGTCATTCGCAATTTTTATGTTTCGGATGACAGATGGCCAATGAC
TTTCAGACTTTCGAGCTTTAAAGGCCTGCCACCATGGGCTAATACATCATGTGTGAGGATTACTGATGTTATACAGGGAGACATTCTCTTTGTCGTCCTGTCAAATTACA
TGGTGGATATTGATTGCTGCTTGATACCTGGTGAGTTCAACCCCCTCTTTTTGGCTCGTGAAATTCTGTCTTTGAATTGTTTCACATTTGTCCAATTCCTCGCAGTGCAT
CGAAGTTGCCTCAGTAGGAAGAAGCCTGCAAATTGGGTTTATCAAAATTCATCTGCAAGAGGATGTGCATTTGAAGATGAGCTGGTTGATTATCTTAGCGCTTTGAAGTT
TAATACTAAGAATCCGTTCACACAAGAACAGTTGGACGAGGGGTCGACAAAGATCACAGAGGCAATAGATGACGTCGAAAGAGGTCGGCAGCGACCAGTAGTTAGAGGTC
GACGGTGGCGATCGGTCAACGAAGGCTGGTCAGCGGAGGTTGACAACGACCGATCGTCGGAGGTCGATTGCGGCCTGTTTGCAGAGCGGAGGTCGGCGGCACCTGGTAGT
TGTAGGTTGACGGTGGCACCCAATAGTCAGAGGTTGATAGTGGCGGTCAGTCAGCAGAGGTCGATCAATGGAGGTCAGCGACGACTAATAGTTAGAGGACGGTGGCGATC
GGTCAGTGGAGGTCGGTGGCGAATAGTAGTCGGAGGTCAATGGTGGCTGTTGGTCAACAGAGGCTGGTCAGCGGAGATCTACAACGGTCGATCGTCGAAGGTCGACGATG
GCAACTGGTCAACGGAGGTTGGTGACGATCAGTTGTCGGAGGTGGATGGTGACAGACGGTCGGCGGAGGTCGATGCTGGCAGTCGATCGAAGGAGGCTCGCCAGCGGAGT
TCGACAACATTCGGTCGTCATAGGTCGACGATAGCGGTCAGCTGCGGCTGGTGGTTAGAGGTTGACAATGGCGACCGATTGACAAAGGTTTACGACGACCAGTAG

mRNA sequence

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Protein sequence

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MGGPLENSQSGILQSKMDDSVEVIRNFYVSDDRWPMTFRLSSFKGLPPWANTSCVRITDVIQGDILFVVLSNYMVDIDCCLIPGEFNPLFLAREILSLNCFTFVQFLAVH
RSCLSRKKPANWVYQNSSARGCAFEDELVDYLSALKFNTKNPFTQEQLDEGSTKITEAIDDVERGRQRPVVRGRRWRSVNEGWSAEVDNDRSSEVDCGLFAERRSAAPGS
CRLTVAPNSQRLIVAVSQQRSINGGQRRLIVRGRWRSVSGGRWRIVVGGQWWLLVNRGWSAEIYNGRSSKVDDGNWSTEVGDDQLSEVDGDRRSAEVDAGSRSKEARQRS
STTFGRHRSTIAVSCGWWLEVDNGDRLTKVYDDQ

Lag0015429 (gene) of Sponge gourd (AG-4) v1 genome