CuGenDBv2

Gene ID	Lag0015533
Organism	Luffa acutangula AG-4 (Sponge gourd (AG-4) v1)
Description	sodium/hydrogen exchanger 8
Genome location	chr12:15396664..15398371
RNA-Seq Expression	Lag0015533
Synteny	Lag0015533
Gene Ontology terms	GO:0051453 - regulation of intracellular pH (biological process) GO:0071805 - potassium ion transmembrane transport (biological process) GO:0098656 - anion transmembrane transport (biological process) GO:0098719 - sodium ion import across plasma membrane (biological process) GO:1902600 - proton transmembrane transport (biological process) GO:0005886 - plasma membrane (cellular component) GO:0016021 - integral component of membrane (cellular component) GO:0015385 - sodium:proton antiporter activity (molecular function) GO:0015386 - potassium:proton antiporter activity (molecular function)
InterPro domains	IPR018422 - Cation/H+ exchanger, CPA1 family

Homology

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GenBank top hits

e value

%identity

Alignment

KAG6601902.1 Sodium/hydrogen exchanger 7, partial [Cucurbita argyrosperma subsp. sororia]

4.4e-16

88.89

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Query:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL
        R   EGA GSSDWNPTDAVLFVGL LVLGIACRHLL+GTRVPYTVALLVLGIIL
Subjt:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL

XP_022955949.1 sodium/hydrogen exchanger 8 isoform X1 [Cucurbita moschata]

4.4e-16

88.89

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Query:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL
        R   EGA GSSDWNPTDAVLFVGL LVLGIACRHLL+GTRVPYTVALLVLGIIL
Subjt:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL

XP_022989835.1 sodium/hydrogen exchanger 8 isoform X1 [Cucurbita maxima]

4.4e-16

88.89

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Query:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL
        R   EGA GSSDWNPTDAVLFVGL LVLGIACRHLL+GTRVPYTVALLVLGIIL
Subjt:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL

XP_023525783.1 sodium/hydrogen exchanger 8 isoform X1 [Cucurbita pepo subsp. pepo]

4.4e-16

88.89

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Query:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL
        R   EGA GSSDWNPTDAVLFVGL LVLGIACRHLL+GTRVPYTVALLVLGIIL
Subjt:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL

XP_038875389.1 sodium/hydrogen exchanger 8 isoform X1 [Benincasa hispida]

1.5e-16

88.89

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Query:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL
        R   EGATGSSDWNPTDAVLFVGL LVLGIACRHLL+GTRVPYTVALLVLGI+L
Subjt:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL

TrEMBL top hits

e value

%identity

Alignment

A0A0A0KJ31 Cyclic nucleotide-binding domain-containing protein

1.4e-15

85.19

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Query:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL
        R   EGAT SSDWNPTDAVLF GL LVLGIACRHLL+GTRVPYTVALLVLGI+L
Subjt:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL

A0A6J1CX31 sodium/hydrogen exchanger 8-like isoform X1

2.8e-16

87.04

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Query:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL
        R   EGA GSSDWNPTDAVLFVGL LVLGIACRHLL+GTRVPYTVALLVLGI+L
Subjt:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL

A0A6J1CZ50 sodium/hydrogen exchanger 8-like isoform X2

2.8e-16

87.04

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Query:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL
        R   EGA GSSDWNPTDAVLFVGL LVLGIACRHLL+GTRVPYTVALLVLGI+L
Subjt:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL

A0A6J1GXP6 sodium/hydrogen exchanger 8 isoform X1

2.1e-16

88.89

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Query:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL
        R   EGA GSSDWNPTDAVLFVGL LVLGIACRHLL+GTRVPYTVALLVLGIIL
Subjt:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL

A0A6J1JNG7 sodium/hydrogen exchanger 8 isoform X1

2.1e-16

88.89

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Query:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL
        R   EGA GSSDWNPTDAVLFVGL LVLGIACRHLL+GTRVPYTVALLVLGIIL
Subjt:  RVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL

SwissProt top hits

e value

%identity

Alignment

Q3YL57 Sodium/hydrogen exchanger 8

1.2e-08

61.7

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Query:  TGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL
        +  +D +P DAV+F G  LVLG ACR+L  GTRVPYTV LLV+GI L
Subjt:  TGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL

Q9LKW9 Sodium/hydrogen exchanger 7

4.9e-10

58.21

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Query:  DSTGLGRVTREGATGSS-------DWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL
        D+T   R   E    SS       + +P DAVLFVG+ LVLGIA RHLL+GTRVPYTVALLV+GI L
Subjt:  DSTGLGRVTREGATGSS-------DWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL

Arabidopsis top hits

e value

%identity

Alignment

AT1G14660.1 Na+/H+ exchanger 8

8.6e-10

61.7

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Query:  TGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL
        +  +D +P DAV+F G  LVLG ACR+L  GTRVPYTV LLV+GI L
Subjt:  TGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL

AT1G14660.2 Na+/H+ exchanger 8

8.6e-10

61.7

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Query:  TGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL
        +  +D +P DAV+F G  LVLG ACR+L  GTRVPYTV LLV+GI L
Subjt:  TGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL

AT2G01980.1 sodium proton exchanger, putative (NHX7) (SOS1)

3.5e-11

58.21

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Query:  DSTGLGRVTREGATGSS-------DWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL
        D+T   R   E    SS       + +P DAVLFVG+ LVLGIA RHLL+GTRVPYTVALLV+GI L
Subjt:  DSTGLGRVTREGATGSS-------DWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL

Sequences

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CDS sequence

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ATGACTCTGAGACTTCTAGAGGCAGGAGACTGGTGGGAGTCTAGAGGTACGACTGTAAAAATTCCGGGATGGGTCGGTTGTACGGACAAATCGACCCGACCCGACCCATG
GTCGGTTGTACGGACAACCCGGACCGACCCGGTCCAGAGTGACTCGACTGGGTTGGGTCGGGTTACCCGCGAGGGAGCCACTGGTTCGTCTGATTGGAATCCAACTGATG
CTGTGCTTTTTGTTGGGCTGATTTTGGTGCTTGGAATTGCTTGCAGACACCTATTGCAAGGCACAAGAGTTCCTTATACAGTTGCCTTGCTCGTTCTTGGCATAATTCTA
ATATCAAGAATTCAACAGTCACGAAATACAACTCGAGCTCGAGCAACCAGTTTTAAGTTTGACGCGGAGGACGATGAGAAGCGTTACGAAAATAAGAACCCCGCAGGCAA
CAACCCAGAAGCTTCAATCAATTACTCTCAATTTCATATCTAA

mRNA sequence

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Protein sequence

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MTLRLLEAGDWWESRGTTVKIPGWVGCTDKSTRPDPWSVVRTTRTDPVQSDSTGLGRVTREGATGSSDWNPTDAVLFVGLILVLGIACRHLLQGTRVPYTVALLVLGIIL
ISRIQQSRNTTRARATSFKFDAEDDEKRYENKNPAGNNPEASINYSQFHI

Lag0015533 (gene) of Sponge gourd (AG-4) v1 genome